Best TWAS P=2.39e-35 · Best GWAS P=7.23e-33 conditioned to 5.47e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | SWAP70 | 0.37 | 0.31 | lasso | 4 | 0.30 | 2.2e-10 | 5.21 | 5.6 | 2.2e-08 | 0.08 | 0.99 | 0.00 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | SWAP70 | 0.17 | 0.05 | lasso | 6 | 0.10 | 1.3e-08 | -11.22 | -7.4 | 1.4e-13 | -0.18 | 0.53 | 0.44 | FALSE |
| 3 | GTEx | Thyroid | SBF2 | 0.11 | 0.01 | enet | 30 | 0.07 | 8.3e-06 | -3.75 | -5.3 | 1.2e-07 | -0.16 | 0.36 | 0.04 | FALSE |
| 4 | NTR | Blood | MRVI1 | 0.07 | 0.00 | blup | 635 | 0.03 | 7.5e-09 | -0.97 | -5.4 | 6.2e-08 | -0.31 | 0.99 | 0.00 | TRUE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | RNF141 | 0.14 | 0.03 | blup | 523 | 0.08 | 1.0e-10 | -4.17 | -5.9 | 3.8e-09 | 0.15 | 0.98 | 0.00 | TRUE |
| 6 | YFS | Blood | ADM | 0.08 | 0.11 | enet | 25 | 0.12 | 9.4e-36 | -5.55 | 8.3 | 7.6e-17 | 0.47 | 1.00 | 0.00 | TRUE |
| 7 | YFS | Blood | SWAP70 | 0.09 | 0.07 | bslmm | 379 | 0.08 | 1.6e-24 | -11.22 | -12.4 | 2.4e-35 | -0.17 | 0.66 | 0.34 | TRUE |
| 8 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SWAP70 | 0.17 | 0.02 | blup | 77 | 0.06 | 1.9e-03 | -11.06 | -9.8 | 1.0e-22 | -0.11 | 0.01 | 0.84 | FALSE |
| 9 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | ST5 | 0.41 | 0.02 | blup | 128 | 0.13 | 2.3e-05 | -3.71 | 5.3 | 1.1e-07 | -0.02 | 0.06 | 0.18 | TRUE |
| 10 | The Cancer Genome Atlas | Thyroid Carcinoma | RPL27A | 0.10 | 0.09 | lasso | 3 | 0.08 | 2.2e-08 | 5.57 | -5.1 | 3.0e-07 | -0.07 | 0.00 | 1.00 | FALSE |