Hub : Genes

MRVI1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2270	0.0460	1.3e-08	0.146	0.096	0.152	0.152	0.143	2.1e-17	8.8e-12	4.5e-18	4.4e-18	4.4e-17
2	METSIM	Adipose	0.0534	0.0197	2.1e-03	0.008	0.019	0.008	0.022	0.009	1.8e-02	6.5e-04	2.0e-02	2.5e-04	1.5e-02
3	NTR	Blood	0.0686	0.0171	2.4e-07	0.001	0.026	0.025	0.023	0.022	2.0e-01	7.5e-09	1.4e-08	4.9e-08	9.1e-08
4	ROSMAP	Brain Pre-frontal Cortex	0.3676	0.0417	0.0e+00	0.295	0.219	0.298	0.298	0.305	2.4e-38	1.1e-27	9.1e-39	8.1e-39	9.4e-40
5	YFS	Blood	0.4907	0.0305	0.0e+00	0.476	0.558	0.587	0.532	0.578	2.5e-179	9.8e-226	8.6e-245	3.4e-210	8.1e-239
6	TCGA	Breast Invasive Carcinoma	0.0445	0.0176	5.2e-05	0.022	0.022	0.010	NA	0.015	1.7e-05	2.3e-05	2.5e-03	NA	3.3e-04
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1500	0.0590	2.6e-03	0.011	0.030	0.057	NA	0.024	7.4e-02	8.0e-03	3.5e-04	NA	1.6e-02
8	TCGA	Brain Lower Grade Glioma	0.0714	0.0286	7.9e-04	0.009	0.030	0.024	NA	0.023	2.8e-02	2.1e-04	7.8e-04	NA	1.1e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.0	1.6	7.0	0.1	1.4	-0.1	0.6	2.6	-1.5	1.1	0.3
Bipolar Disorder or Schizophrenia	0.3	0.8	3.4	-0.3	0.7	-1.0	-0.0	1.8	-1.2	0.2	0.3
Depressed Affect (Nagel 2018)	0.6	1.2	3.9	-1.0	0.8	2.0	-0.9	-0.4	0.6	-0.7	-1.3
Depression (Nagel 2018)	0.7	1.1	4.4	-0.1	1.1	2.1	-0.0	1.3	0.4	-1.0	-0.5
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.7	1.3	-0.3	-0.6	1.2	-1.1	-0.4	0.6	0.8
Neuroticism (Nagel 2018)	0.8	2.0	3.1	-1.6	0.1	1.5	-1.4	-1.0	-1.2	-1.8	-1.8
Schizophrenia (2018)	0.2	0.3	1.4	-0.5	-0.2	-1.2	-0.5	0.3	-0.4	-0.7	0.1
Schizophrenia vs Biploar Disorder	0.7	0.9	1.3	1.1	-1.2	-0.7	0.8	-1.1	1.1	0.8	0.9
Worry (Nagel 2018)	0.6	1.4	4.9	-0.7	-1.1	-0.2	-0.6	-1.1	-1.3	-2.2	-1.0
Alzheimer’s Disease (in mother)	1.4	1.6	3.0	1.3	1.3	0.9	1.7	0.5	1.7	0.2	1.7
Alzheimer’s Disease (in father)	0.7	0.8	2.0	0.7	0.9	0.6	1.0	-0.5	1.4	0.9	-0.6
Alzheimer’s Disease (including proxy)	1.1	1.5	5.4	0.8	1.6	1.3	1.3	-0.0	2.3	0.3	-0.0
Crohns Disease (2017)	1.5	3.4	7.6	-2.0	0.5	1.2	-2.6	-0.1	-2.1	-1.4	-2.8
Irritable Bowel Disease (IBD)	1.7	4.1	10.2	-2.2	1.0	1.5	-2.9	-0.9	-2.2	-0.8	-3.2
Ulcerative Colitis (UC)	1.0	1.9	3.9	-1.3	1.1	1.3	-1.8	-1.0	-1.7	-0.4	-2.0
Major Depression (MDD)	1.3	1.6	4.8	-1.6	1.1	1.2	-2.2	0.2	-0.1	0.0	-1.7
Reaction Time	0.5	1.0	3.6	-0.6	1.9	-0.1	-0.4	-0.6	1.2	-0.6	-1.4
Verbal and Numeric Reasoning (VNR)	0.9	2.1	6.2	-0.7	1.8	1.4	-0.2	0.4	-2.2	-2.5	-0.3
Breast Cancer	0.6	1.4	6.1	0.3	-1.0	-0.2	0.5	-2.5	0.1	0.4	1.9
Ovarian Cancer	1.1	1.5	4.6	2.1	-0.7	-0.7	1.9	0.1	0.6	0.7	1.5
Prostate Cancer	0.4	0.6	2.9	0.4	0.4	0.0	1.0	0.0	-0.2	-0.9	1.7
Age at First Birth	0.2	0.3	0.9	0.5	-0.3	-0.1	0.9	0.5	-0.9	0.4	0.3
Bipolar Disorder (2011)	1.5	1.5	4.9	-1.4	1.1	0.1	-1.3	1.1	-2.2	-0.5	-0.7
Body Mass Index (BMI) (2010)	0.3	0.4	2.0	0.3	-0.6	0.1	0.5	1.4	0.5	0.0	0.6
Coronary Artery Disease (CAD)	0.5	0.7	2.0	-0.9	-1.4	-0.2	-0.9	0.6	0.3	-0.9	0.4
Crohns Disease (2012)	2.0	3.3	8.8	-2.1	0.4	1.1	-2.6	-0.2	-1.5	-1.7	-3.0
Mean Putamen Volume	1.4	1.6	5.1	-1.4	1.3	-1.1	-0.8	0.8	-2.2	-1.1	-0.5
Fasting Glucose	1.0	1.2	2.8	-1.6	0.9	-0.0	-1.7	0.9	-0.4	-1.0	-1.1
HbA1C	0.3	0.4	1.1	-0.6	-1.1	0.1	-0.2	-0.6	0.9	0.2	-0.4
HDL Cholesterol	0.4	0.7	2.0	-0.3	-1.0	1.4	-0.6	1.1	-1.0	0.1	-0.0
LDL Cholesterol	0.6	1.0	3.1	0.9	-0.9	1.8	0.1	-0.9	-0.0	0.8	1.1
Lupus	0.4	0.6	2.2	0.2	1.1	0.6	-0.3	1.5	-0.8	-0.3	-0.7
Neuroticism (2016)	2.8	4.0	10.8	-2.4	-0.8	1.1	-2.9	-0.4	-0.8	-2.1	-3.3
Primary Biliary Cirrhosis	1.4	2.0	5.1	-2.3	0.7	0.7	-1.5	1.2	-1.9	-1.5	-0.7
Rheumatoid Arthritis	0.8	1.1	3.3	-0.1	1.5	0.8	-0.9	-0.0	-1.1	-1.8	-0.3
Schizophrenia (2014)	0.3	0.6	2.1	-0.3	0.3	-1.4	0.3	1.2	0.1	0.3	1.0
Triglycerides	0.8	1.3	4.0	1.1	1.5	-0.4	1.0	-0.6	2.0	0.7	0.8
Type 2 Diabetes (T2D) (2012)	0.9	1.0	3.2	1.8	1.4	1.1	0.7	0.1	-0.8	-0.4	0.4
Ulcerative Colitis	2.3	3.4	8.8	-2.5	0.2	0.2	-2.5	-1.7	-1.6	-0.4	-3.0
Blood Eosinophil Count	0.3	2.3	3.7	-1.6	1.4	-0.2	-1.6	1.9	-1.0	-1.7	-1.9
Blood Platelet Count	0.4	4.6	19.3	0.8	2.5	4.4	0.6	0.9	1.7	-0.5	2.5
Blood Red Count	0.8	7.7	13.5	2.8	1.9	3.1	3.1	1.4	3.5	2.0	3.7
Blood White Count	0.1	0.8	2.8	-0.3	1.7	-0.6	-0.3	-1.2	-0.4	0.9	-0.6
Heel T-Score	0.1	0.7	2.7	-0.0	-0.1	1.0	0.7	-0.8	-1.6	-0.6	-0.8
BMI	0.3	1.6	6.2	0.7	0.2	0.3	0.8	-2.5	1.5	1.5	-1.0
Height	0.1	2.4	7.8	-1.3	1.7	2.8	-1.7	1.2	-1.1	-0.3	-1.1
Waist Hip Ratio (WHR)	1.3	5.8	22.3	-2.3	-0.9	4.7	-2.1	2.1	-0.8	-2.8	-0.5
Systolic Blood Pressure	1.9	9.6	29.3	2.9	-2.3	-5.4	3.4	-4.4	-0.8	0.3	1.5
Smoking Status	0.6	1.5	5.2	0.8	1.9	1.5	0.6	2.3	-0.3	-0.0	0.5
Allergy or Eczema	2.9	7.5	17.0	-4.1	0.3	0.9	-3.8	0.6	-3.6	-2.0	-3.2
Cardiovascular Disease	1.1	3.8	8.6	2.1	0.1	-1.5	2.4	-2.9	1.7	1.6	1.8
Hypothyroidism (self reported)	1.0	2.4	6.8	1.7	-0.2	-1.3	2.6	1.4	1.1	0.2	2.0
Respiratory disease	1.2	2.7	5.7	-1.6	-1.9	-1.4	-1.3	-2.2	-2.4	-0.9	-0.9
Type 2 Diabetes (T2D) (2018)	1.2	2.3	5.2	0.8	0.9	1.2	1.2	-1.8	2.0	1.3	2.3
Lung FEV1/FVC ratio	1.5	7.6	21.3	-2.0	2.0	4.6	-2.9	4.2	-0.7	-1.4	-1.5
Lung FVC	0.8	4.2	9.3	2.3	0.7	1.1	2.6	2.8	1.2	1.0	3.0
Neuroticism	0.4	1.0	2.9	-1.2	-0.7	0.3	-1.0	-1.4	-0.2	-1.7	-0.5
Chronotype (morning person)	1.0	2.2	4.5	-1.5	0.4	1.5	-2.1	-0.6	1.1	-2.0	-1.7
Hair Pigment	0.0	0.8	2.8	0.6	1.4	1.7	0.0	0.8	0.8	0.4	0.3
Tanning	0.2	2.0	10.6	-0.2	-3.2	-1.4	-0.4	-1.0	1.1	0.9	0.8
Hand grip strength (left)	0.1	0.3	1.1	0.5	1.1	0.3	0.3	-0.2	0.5	0.5	0.9
Number of treatments/medications taken	1.8	3.3	8.7	2.3	-0.8	0.6	2.9	-0.8	1.9	0.3	2.6
Average weekly spirits intake	0.9	1.1	3.9	0.3	0.2	-0.9	-0.0	-0.7	-2.0	-1.8	-0.1
Sensitivity / hurt feelings	0.5	0.8	1.7	-0.8	-1.3	1.1	-1.3	-0.2	-0.2	0.0	-1.3
Frequency of depressed mood in last 2 weeks	0.8	1.2	4.7	-0.5	1.4	2.2	-0.6	0.6	0.4	-0.7	-1.0
Hearing difficulty/problems: Yes	1.0	1.6	3.1	1.7	0.3	0.2	1.7	-1.8	0.6	0.3	1.7
Relative age of first facial hair	0.2	0.4	2.2	-0.1	0.4	0.0	-0.6	0.0	-1.5	-0.8	-0.2
Other serious medical condition/disability diagnosed by doctor	1.0	1.2	3.5	-1.9	-0.3	1.0	-1.1	-0.9	-1.3	0.3	-1.3
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.3	0.4	-0.9	1.5	0.5	-0.4	0.5	-0.4	1.5
Ever had hysterectomy (womb removed)	1.1	1.2	5.5	-0.1	0.0	2.4	0.4	0.4	0.5	-1.0	1.6
Systolic blood pressure, automated reading	1.4	4.0	10.8	1.0	-3.3	-3.0	1.4	-2.6	-1.1	-0.8	-0.7
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	4.5	-1.2	0.2	0.9	-1.3	-0.8	-2.1	-1.4	-0.3
Angina	0.3	0.4	1.0	-0.2	-0.4	-1.0	-0.1	0.5	-1.0	-0.6	0.1
Medication for hormone replacement therapy	0.7	0.8	3.2	1.1	-0.2	1.1	0.5	0.3	-0.3	0.2	1.8
Vitamin and mineral supplements	0.7	1.0	2.7	0.8	0.7	-0.8	1.2	-0.7	1.1	-1.6	0.6
Supplements: Zinc	2.7	2.9	7.4	1.5	-1.4	-2.2	1.8	0.2	0.9	2.7	1.8
Medication: Co-codamol	1.3	1.5	3.8	-1.9	-0.1	0.9	-1.9	1.2	0.7	0.1	-1.4
Medication: Metformin	1.1	1.6	4.7	0.5	0.6	0.7	1.0	-1.9	1.0	1.0	2.2
Diabetes (father)	1.0	1.2	3.5	1.0	1.0	1.7	1.0	1.9	0.6	0.4	0.0
Diabetes (mother)	0.5	0.6	2.5	-0.6	-1.6	-1.3	-0.0	-0.1	-0.2	-0.4	-0.0
Severe depression (siblings)	0.9	1.0	2.4	1.6	-0.4	0.6	1.3	-0.3	-1.4	-0.9	0.7
Pack years adult smoking proportion	0.5	0.8	5.2	0.0	1.0	-0.2	0.4	0.2	-0.2	-2.3	0.2
Impedance of leg (right)	0.3	1.6	5.8	0.3	-0.1	2.0	0.0	2.4	0.4	-1.0	1.3
Leg fat-free mass (left)	0.3	1.6	5.1	-1.0	0.7	-0.2	-1.1	-2.3	-1.0	0.2	-1.9
Trunk fat percentage	0.2	1.0	2.3	-0.4	-1.0	0.9	-0.2	-1.0	0.6	-1.5	-1.4
Hand grip strength (right)	0.2	0.6	1.9	-0.6	0.7	1.4	-1.1	-0.3	-0.4	0.5	0.4
Townsend deprivation index at recruitment	0.2	0.4	1.0	-0.8	-0.7	0.3	-1.0	0.5	-0.4	0.3	-0.4
Current tobacco smoking	0.8	1.3	4.3	0.5	1.1	1.9	-0.2	2.1	0.8	-0.0	-0.9
Average weekly fortified wine intake	0.3	0.4	0.8	0.6	-0.7	-0.8	0.5	0.2	0.4	0.9	0.5
Maternal smoking around birth	0.2	0.2	0.5	-0.3	-0.3	0.7	0.5	0.1	0.7	-0.7	0.1
Fed-up feelings	0.5	1.0	2.5	0.6	1.2	1.6	0.9	0.5	0.7	-1.2	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.9	-0.4	-0.4	1.7	-0.5	1.1	0.5	-0.2	-0.7
Relative age voice broke	0.3	0.4	1.8	0.2	0.6	-0.1	-0.6	1.3	-0.6	-0.2	-0.5
Taking other prescription medications	0.5	0.7	3.8	-0.2	-0.1	0.8	0.3	-0.9	-0.5	-2.0	-0.2
Age when periods started (menarche)	1.1	2.6	7.5	-1.1	-2.3	-2.7	-1.3	-2.2	-0.4	-0.1	-0.6
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	3.2	-0.2	-1.8	1.6	-0.1	-1.0	1.5	0.7	0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	4.9	2.1	0.9	0.2	2.2	0.4	-1.0	-1.3	0.7
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	3.7	-1.3	1.9	-0.3	-1.6	0.8	-0.9	-1.0	-1.6
Qualifications: CSEs or equivalent	1.8	2.3	5.9	-1.9	1.6	1.8	-1.7	0.3	-0.4	-2.4	-0.4
Serious illness, injury or assault to yourself	1.1	1.3	2.9	1.7	0.1	-0.1	1.5	-1.3	1.0	0.0	1.6
High blood pressure	1.3	3.5	6.3	2.0	-2.2	-0.9	2.5	-2.3	1.1	1.5	1.8
Hayfever, allergic rhinitis or eczema	2.3	4.9	11.3	-3.4	0.9	0.1	-3.0	0.7	-3.0	-1.6	-2.5
Multivitamins +/- minerals	1.2	1.5	3.5	-1.7	0.7	1.2	-1.9	0.2	-1.2	1.1	-0.9
Stomach or abdominal pain in last month	1.4	1.8	6.9	-1.3	-0.4	-0.3	-1.7	-0.8	-2.6	-0.1	-1.4
Supplements: Glucosamine	1.0	1.3	4.9	0.5	-1.2	1.9	0.3	-0.2	-0.2	2.2	0.5
Diverticular disease/diverticulitis (self-reported)	1.9	2.2	4.4	-1.6	0.4	2.0	-1.8	2.1	0.3	-1.0	-1.6
Medication: Atenolol	1.2	1.5	4.0	1.9	-1.0	-1.2	2.0	0.2	-0.2	0.8	1.2
Medication: Levothyroxine sodium	1.1	1.8	5.7	1.7	0.0	-0.7	2.4	0.7	1.5	0.4	1.5
Sitting height	0.1	0.8	1.9	0.8	1.1	0.1	0.6	-0.9	-1.4	0.6	1.0
Chronic bronchitis/emphysema (father)	0.6	0.8	3.4	0.7	0.3	0.5	0.4	-1.9	0.1	1.2	0.4
High blood pressure (mother)	1.8	2.6	9.9	1.3	-1.1	-3.1	1.7	-1.0	-0.2	2.0	0.7
Body mass index (BMI)	0.2	0.9	4.6	0.4	-0.6	0.3	0.5	-2.1	0.8	-0.2	-0.9
Impedance of leg (left)	0.6	2.8	9.8	0.8	0.0	2.6	0.6	3.1	0.7	-1.1	1.9
Leg predicted mass (left)	0.3	1.7	5.1	-1.1	0.7	-0.1	-1.2	-2.3	-1.1	0.2	-1.9
Trunk fat mass	0.2	0.8	2.4	-0.4	-0.7	0.9	-0.2	-1.5	0.2	-1.1	-1.3
Waist circumference	0.2	0.9	3.6	-0.2	-0.6	1.7	0.1	-1.9	0.3	-0.5	-0.1
Number of incorrect matches in round	1.6	2.6	4.8	1.7	-1.7	-2.2	2.0	-0.5	0.0	1.5	2.0
Past tobacco smoking	0.9	1.7	6.4	0.1	-2.5	-2.0	0.0	-0.2	1.3	-1.1	-0.5
Alcohol usually taken with meals	1.4	2.3	6.3	1.1	-1.7	-1.9	0.8	-1.7	-0.6	2.5	0.5
Nervous feelings	1.2	2.2	8.0	-1.5	-0.7	-0.2	-1.5	0.3	-1.3	-2.8	-1.8
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	3.3	0.6	0.1	0.9	0.1	-0.6	1.8	0.4	0.1
Hearing difficulty/problems with background noise	5.1	8.2	14.8	3.5	0.1	-1.1	3.9	-3.4	3.0	2.3	3.5
Hair/balding pattern: Pattern 2	0.6	0.7	1.3	0.8	1.1	-0.8	0.9	0.6	-0.9	-1.1	-0.0
Had menopause	0.7	0.9	2.2	0.7	-1.4	0.8	0.7	-0.3	1.1	0.3	1.5
Had other major operations	0.4	0.5	1.2	0.0	-0.8	0.9	0.4	1.1	0.1	-1.0	0.3
Forced vital capacity (FVC)	0.6	2.4	11.0	0.0	2.3	1.6	0.3	3.3	-0.2	-0.1	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	4.3	2.1	1.3	0.4	2.1	0.8	-1.1	-0.9	0.5
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.3	0.1	0.2	-0.1	-0.1	0.2	1.5	1.2	-0.5
Qualifications: None of the above	0.1	0.3	1.0	-0.6	-1.0	-0.0	-0.4	-0.2	0.8	-0.6	0.0
Financial difficulties in last 2 years	0.1	0.1	0.6	-0.1	-0.1	0.1	0.1	0.2	0.8	0.3	-0.2
Mouth/teeth dental problems	1.2	1.9	5.4	1.1	-0.3	-2.3	1.8	0.5	-1.3	0.7	1.6
Heart attack	0.6	0.7	2.2	-1.4	0.1	-0.2	-1.5	-0.6	-0.8	0.3	-0.8
Allergy	1.8	4.0	10.4	3.2	0.2	0.6	2.7	-0.1	2.2	2.0	2.3
Pain all over the body in last month	3.2	3.5	8.2	2.8	1.4	1.1	2.8	0.6	0.6	-0.3	2.9
Diabetes (self-reported)	1.3	2.1	7.5	0.4	-0.9	1.0	1.0	-2.7	1.8	1.2	1.2
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.4	-0.4	-1.1	-1.2	-0.6	0.4	-1.2	-0.4	-0.3
Medication: Ramipril	0.4	0.6	1.2	0.9	0.6	0.3	0.5	-0.9	-0.9	0.4	1.1
Medication: Simvastatin	0.5	0.7	2.5	0.9	-0.6	-0.7	0.5	-1.6	0.7	1.1	0.3
Fluid intelligence score	0.9	2.0	7.0	-1.4	1.1	1.0	-1.1	0.1	-2.6	-1.0	-1.5
Illnesses of siblings	0.4	0.5	1.6	0.4	1.1	-0.3	0.2	1.3	0.5	-0.8	0.5
Neuroticism score	0.3	0.7	2.4	-0.6	-1.1	0.6	-0.6	-0.5	-0.1	-1.5	-0.9
Weight	0.2	0.8	4.0	-0.2	0.1	1.0	-0.2	-2.0	-0.0	-0.0	-1.1
Impedance of arm (right)	0.3	1.3	4.1	-1.0	-0.3	-1.0	-0.5	2.0	-0.1	-2.0	-0.2
Arm fat percentage (right)	0.2	0.9	2.0	-0.4	-1.0	0.1	-0.1	-1.4	0.3	-1.4	-1.4
Trunk fat-free mass	0.1	0.8	3.0	-0.4	0.6	0.5	-0.9	-1.7	-1.0	0.7	-0.9
Hip circumference	0.3	1.4	8.5	0.7	0.7	-0.5	0.7	-2.9	0.4	0.3	-0.7
Time employed in main current job	1.3	1.5	5.9	-0.7	0.5	2.4	-0.8	0.4	-1.1	-1.8	0.1
Alcohol intake versus 10 years previously	0.4	0.5	1.0	-0.3	-0.7	0.8	-0.4	0.9	-0.8	0.7	1.0
Father’s age at death	1.3	1.7	3.3	-0.8	0.6	-1.1	-1.0	1.2	-1.7	-1.8	-1.6
Worrier / anxious feelings	0.5	0.9	3.6	-0.5	-0.1	0.8	-0.5	-0.6	-0.4	-1.5	-1.9
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	3.4	1.0	1.5	1.8	1.2	0.9	1.7	-0.3	1.2
Falls in the last year	0.9	1.2	5.8	-0.4	1.1	2.4	0.1	1.4	0.1	-0.5	0.4
Hair/balding pattern: Pattern 3	0.4	0.6	1.5	-0.5	-0.2	-0.4	-0.7	-1.0	-1.1	1.2	-0.6
Number of live births	0.9	1.2	3.1	1.7	-0.5	-0.1	1.8	-0.3	1.1	0.8	1.4
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	17.3	0.5	2.2	2.5	0.2	4.2	0.1	-0.1	0.5
Pulse rate	0.5	0.8	3.0	-0.1	-0.4	0.9	-0.1	0.6	1.7	-1.5	-0.0
Happiness	0.4	0.5	2.5	-0.4	0.3	-0.6	-0.7	-0.3	0.3	-0.6	-1.6
Noisy workplace	1.4	1.7	4.0	-0.8	-0.3	1.4	-1.4	-0.7	-1.9	-2.0	-0.8
Qualifications: A levels/AS levels or equivalent	0.5	1.1	2.2	1.4	1.3	-0.2	1.5	0.5	-0.9	1.3	0.5
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	2.8	-0.6	0.6	1.2	-0.9	0.7	-1.7	-1.5	-1.1
Mouth/teeth dental problems: Dentures	1.0	1.7	7.0	-0.5	1.9	2.6	-0.8	0.1	-0.0	-1.1	-0.9
Asthma	0.9	1.7	5.2	-1.1	-1.4	-1.6	-0.5	-1.6	-2.3	-0.3	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.9	2.4	6.9	1.0	0.0	0.9	1.2	2.2	2.6	0.6	2.1
Medication: Cholesterol lowering	0.9	1.5	8.3	0.0	-0.1	-0.1	0.2	-2.9	0.5	1.7	0.5
Depression (self-reported)	0.9	1.1	2.2	-1.1	0.2	0.1	-1.4	-1.5	-1.2	-0.9	-1.1
Medication: Lansoprazole	0.6	0.7	2.9	-0.4	-0.9	1.1	-0.4	-0.0	0.2	-1.7	-0.5
Prospective memory result	0.5	0.6	1.1	-1.0	-0.5	-0.7	-1.0	-0.6	0.9	-1.0	-0.3
Lung cancer (father)	0.2	0.2	0.6	-0.1	-0.2	0.3	-0.3	0.4	-0.8	0.0	-0.7
Illnesses of mother	0.8	1.0	2.7	1.1	0.9	1.6	0.3	0.8	0.4	-1.5	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.8	15.9	-0.3	2.5	2.6	-0.6	4.0	0.1	-1.2	0.3
Pulse wave Arterial Stiffness index	0.4	0.5	1.5	-0.1	-0.1	0.8	0.6	0.6	1.2	-0.4	0.9
Impedance of arm (left)	0.2	0.9	2.4	-0.7	-0.6	-1.3	-0.2	1.5	0.2	-1.6	0.0
Arm fat mass (right)	0.2	1.0	3.0	-0.8	-0.7	0.5	-0.7	-1.7	0.4	-0.7	-1.6
Trunk predicted mass	0.1	0.8	2.9	-0.4	0.6	0.5	-0.8	-1.7	-0.9	0.7	-0.8
Standing height	0.1	1.4	2.8	-1.1	1.5	1.7	-1.3	0.5	-1.6	0.3	-0.4
Length of working week for main job	0.8	0.8	3.3	-0.4	-0.9	0.7	-0.7	0.2	-1.2	-1.8	0.3
Exposure to tobacco smoke at home	0.4	0.4	1.3	-0.2	-0.7	-0.7	0.2	-0.9	-0.4	0.2	1.1
Breastfed as a baby	1.2	1.5	4.4	1.3	0.6	-1.2	1.8	2.1	-0.7	0.6	0.3
Tense / ‘highly strung’	0.6	0.9	2.1	-1.5	-0.9	0.5	-1.3	-1.1	0.5	-0.6	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	2.0	1.1	-0.8	1.4	0.5	-1.3	-0.3	1.3	0.2
Hair/balding pattern: Pattern 4	0.1	0.3	1.7	-0.4	-0.2	-0.3	0.0	1.3	0.4	-0.5	0.2
Birth weight of first child	0.6	1.1	3.0	0.7	0.2	-0.1	0.1	1.5	-1.7	-1.5	-0.8
Peak expiratory flow (PEF)	1.9	4.5	24.6	0.7	1.7	2.6	0.2	5.0	-1.0	-0.5	0.2
Pulse wave reflection index	1.3	1.6	3.8	1.2	1.2	1.6	2.0	1.4	-0.0	0.2	1.3
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.9	-0.8	-0.1	-0.5	-0.7	0.1	0.4	-1.1	-1.7
Loud music exposure frequency	0.8	0.9	2.7	-0.9	0.4	-1.1	-0.7	-0.4	1.1	0.4	-1.6
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	2.9	0.0	-0.5	0.7	-0.1	1.7	-0.1	0.8	-0.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.6	-0.3	-0.8	0.4	-0.5	0.3	0.4	-0.4	-0.6
Blood clot in the leg (DVT)	0.7	0.9	2.6	-0.0	1.6	-0.8	-0.1	0.7	0.6	-0.6	-1.5
Medication: Paracetamol	3.0	4.9	13.6	2.1	0.3	-0.2	3.0	1.5	3.7	1.9	2.5
Headache pain in last month	1.8	3.1	10.0	1.1	1.1	2.1	0.8	-0.2	3.2	0.7	2.5
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	4.3	-0.3	-0.0	-0.4	-0.5	2.1	-0.2	-1.4	-0.2
Glaucoma (self-reported)	1.1	1.3	2.6	0.4	1.2	-1.4	1.6	0.9	-0.9	1.5	0.1
Gout (self-reported)	1.8	2.4	5.9	2.3	0.3	-0.9	2.1	-0.9	2.4	-0.1	1.4
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	5.1	1.5	-0.4	-1.0	2.3	0.9	1.3	0.2	1.7
Medication: Amlodipine	1.2	1.7	3.4	-1.9	-1.7	-0.9	-1.8	-0.6	-0.6	-0.0	-1.5
Medication: Ventolin 100micrograms inhaler	1.7	2.2	5.1	-0.9	-2.3	-1.9	-0.4	-2.2	-0.3	1.5	-0.7
Birth weight	1.0	2.1	9.5	0.8	-0.1	-2.1	0.4	-0.3	1.5	3.1	-0.1
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.3	0.4	-0.1	-0.8	1.0	-1.2	0.3	0.1	0.1
High blood pressure (siblings)	1.0	1.4	4.1	0.8	-1.4	-0.8	1.1	-2.0	-0.6	1.6	-0.3
Forced vital capacity (FVC), Best measure	0.6	2.2	9.2	-0.7	2.3	1.2	-0.5	3.0	-0.3	-0.6	0.3
Body fat percentage	0.2	1.0	2.2	-0.2	-1.2	1.1	-0.0	-1.0	0.5	-1.5	-1.3
Leg fat percentage (right)	0.2	0.8	2.0	0.6	-0.9	1.4	0.6	-1.0	0.6	-1.1	-0.6
Arm fat-free mass (right)	0.1	0.7	2.9	-0.2	0.5	1.1	-0.6	-1.7	-0.3	0.8	-0.6
Exposure to tobacco smoke outside home	0.3	0.3	1.1	-0.5	0.7	1.1	0.1	0.3	-0.6	-0.7	-0.1
Comparative body size at age 10	0.4	1.2	2.8	-0.2	1.7	0.7	-0.1	1.1	-0.4	-1.6	-1.5
Number of full brothers	0.7	0.8	2.2	0.1	-0.2	-1.3	0.7	-0.3	0.9	1.2	1.5
Worry too long after embarrassment	0.4	0.7	2.5	-0.9	0.5	0.7	-0.8	0.2	-0.4	-1.6	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	2.0	1.3	0.1	-0.7	1.4	-0.7	-0.2	-0.2	1.0
Wheeze or whistling in the chest in last year	0.8	1.5	3.3	-1.4	-0.5	-1.1	-0.9	-0.6	-1.4	-1.4	-1.8
Number of children fathered	2.9	3.3	7.7	0.9	-2.0	-0.8	1.8	-1.3	2.8	1.5	2.4
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.3	1.1	-0.5	-0.4	1.5	-0.3	0.4	-0.6	1.5
Age at first live birth	1.1	2.0	7.7	0.0	-0.4	-2.8	0.2	-1.0	-1.5	1.9	-1.1
Pulse wave peak to peak time	0.4	0.5	1.3	0.1	0.2	-0.8	-0.6	-0.6	-1.1	0.6	-1.0
Health satisfaction	1.4	1.8	5.3	-2.3	-0.7	-1.0	-1.4	-0.3	0.7	-2.2	-0.2
Shortness of breath walking on level ground	1.4	1.6	6.3	-0.1	-1.7	-1.1	1.0	-1.2	2.5	-0.3	0.4
Qualifications: College or University degree	0.4	1.1	4.5	0.2	2.1	-0.8	0.7	-0.1	-1.9	-0.0	0.2
Eye problems/disorders: None of the above	0.9	1.0	2.9	1.3	-0.7	-0.4	0.6	-0.1	1.7	1.4	0.8
Mouth/teeth dental problems: Loose teeth	0.4	0.5	2.5	0.5	0.2	0.9	-0.2	-1.6	-0.5	0.1	0.2
Emphysema/chronic bronchitis	0.7	0.8	1.6	-1.3	0.7	0.6	-1.2	1.2	-0.1	-0.7	-0.7
Medication for pain relief, constipation, heartburn	1.3	2.3	8.5	-1.1	-0.2	-0.6	-1.4	-1.5	-2.9	-0.5	-1.9
Neck or shoulder pain in last month	1.4	2.0	4.9	2.0	0.2	1.1	1.1	1.4	0.1	-2.2	1.6
Medication: Blood pressure	0.2	0.4	1.1	0.7	-0.4	-0.3	0.9	-1.1	-0.2	0.4	0.3
Angina (self-reported)	0.3	0.4	1.0	-0.0	-0.2	-0.9	0.2	0.6	-1.0	-0.8	0.2
Migraine (self-reported)	7.4	9.2	21.6	4.6	1.0	1.6	3.9	1.4	4.2	0.1	3.7
Medication: Ibuprofen	1.4	1.7	3.9	1.2	0.0	0.2	1.4	1.5	1.8	0.5	2.0
Medication: Allopurinol	1.2	1.7	3.3	1.5	0.6	-1.2	1.7	-1.4	1.8	0.2	1.0
Medication: Omeprazole	0.9	1.0	4.3	0.8	0.2	2.1	0.8	1.4	0.2	-0.8	0.1
Medication: Seretide 50 evohaler	0.4	0.4	1.4	-0.3	0.2	-1.0	0.7	-1.2	-0.1	0.5	0.3
Mean time to correctly identify matches	0.4	0.7	2.8	-0.3	0.5	-0.2	-0.0	-1.3	1.7	0.0	-0.8
Heart disease (mother)	0.6	0.7	1.3	-0.7	-0.2	0.7	-0.8	0.9	-1.0	-1.2	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.3	-0.8	0.7	1.1	-0.7	-0.8	-0.8	-0.5	-0.3
Whole body fat mass	0.2	0.9	1.9	-0.4	-0.5	1.2	-0.3	-1.4	-0.1	-1.1	-1.3
Leg fat mass (right)	0.2	0.8	2.5	0.2	-0.5	1.3	0.1	-1.6	0.3	-0.7	-1.1
Arm predicted mass (right)	0.1	0.7	2.4	-0.0	0.4	1.3	-0.5	-1.6	-0.2	0.7	-0.6
Pulse rate, automated reading	1.0	3.4	14.1	-1.5	0.7	3.8	-1.8	1.3	0.1	-2.1	-1.0
Alcohol intake frequency.	1.0	2.4	5.0	2.1	-0.5	0.2	2.2	1.2	1.7	0.9	2.1
Comparative height size at age 10	0.2	1.2	7.3	-0.5	0.7	2.7	-0.7	0.7	-0.5	0.4	0.2
Number of full sisters	5.7	7.0	14.5	3.5	-0.9	-0.3	3.8	-0.6	3.0	3.0	3.0
Suffer from ‘nerves’	0.3	0.4	1.4	-0.3	-1.2	0.2	-0.5	-0.7	-0.5	-0.8	0.0
Overall health rating	0.9	2.0	4.5	-1.8	0.7	2.1	-1.6	-0.5	0.1	-1.7	-1.5
Chest pain or discomfort	1.0	1.5	7.8	-1.0	0.5	0.3	-0.6	-0.4	-2.8	-1.4	-0.5
Had major operations	1.0	1.2	4.8	-0.2	1.3	0.5	-0.3	2.2	-0.6	-0.5	-1.4
Age at last live birth	1.1	1.6	6.1	-0.9	-0.3	-2.5	-0.7	0.1	-1.7	0.3	-1.5
Family relationship satisfaction	0.7	0.8	2.8	0.6	-0.1	-1.7	0.7	-1.4	-0.9	-0.2	0.6
Leg pain on walking	0.3	0.4	1.4	0.1	-0.7	-0.7	0.5	0.2	1.2	-0.7	0.2
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	4.9	1.4	-0.3	0.3	1.5	0.6	2.2	1.1	1.3
Commuting to job workplace: Car/motor vehicle	1.5	1.7	3.6	1.7	-1.8	0.4	1.9	-0.5	0.7	0.9	1.7
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.1	0.3	-0.2	-0.9	0.7	-0.3	0.3	1.0	1.1
Medication: Aspirin	0.1	0.1	0.3	-0.1	0.2	0.3	-0.1	-0.5	-0.1	-0.3	0.3
Supplements: Vitamin C	1.3	1.6	6.0	0.7	-2.4	-1.3	0.1	-0.3	-0.4	1.9	0.4
Knee pain experienced in last month	0.9	1.4	4.9	-0.4	-2.2	-0.9	-0.9	-0.6	-0.0	-1.9	-0.5
Hypertension (Self-reported)	1.3	3.6	7.5	2.1	-1.9	-1.0	2.7	-2.1	1.1	1.6	2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.3	3.9	-0.8	-1.4	2.0	-1.1	-0.2	-0.7	-1.4	-0.6
Illnesses of father: Heart disease	0.7	1.0	5.4	-1.0	-0.5	2.3	-1.1	-0.1	0.2	-0.0	0.0
Illnesses of siblings: Diabetes	0.8	1.0	2.7	-0.5	-1.2	-0.5	-0.2	-0.6	1.4	1.6	-0.9
Smoking status: Previous	0.6	0.9	4.2	-0.3	2.0	0.9	-0.3	0.3	-1.2	0.3	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	3.7	-1.0	1.4	1.3	-1.5	1.2	-0.4	-0.1	-1.9
Whole body fat-free mass	0.2	1.1	3.6	-0.7	0.7	0.4	-1.0	-1.9	-0.9	0.5	-1.3
Leg fat-free mass (right)	0.2	1.1	3.7	-0.8	0.8	-0.0	-0.9	-1.9	-0.8	0.1	-1.6
Arm fat percentage (left)	0.2	0.9	2.3	-0.2	-1.0	-0.1	0.1	-1.5	0.6	-1.2	-1.4
Average weekly red wine intake	0.4	0.5	1.6	-0.7	0.0	0.4	-1.0	-1.3	-1.0	0.3	-0.3
Handedness (chirality/laterality): Left-handed	1.1	1.3	4.4	0.3	2.1	1.4	0.5	-1.6	-0.2	-0.8	0.7
Mood swings	0.4	0.8	3.2	-0.1	-0.2	1.8	-0.5	-0.0	0.7	-0.4	-1.4
Loneliness, isolation	0.4	0.5	1.4	-0.7	-0.1	-0.0	-0.8	-0.7	0.8	-0.5	-1.2
Long-standing illness, disability or infirmity	0.5	0.8	3.7	-0.5	-1.0	0.9	0.3	-1.9	-0.2	0.4	0.2
Ever had bowel cancer screening	1.0	1.1	3.7	0.9	-0.9	-0.1	1.1	1.9	-1.2	0.5	0.8
Diabetes diagnosed by doctor	1.2	1.9	4.6	0.7	0.2	1.7	1.1	-2.1	1.1	1.4	1.7
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.3	1.1	-0.1	-0.9	1.1	0.1	0.6	-0.9	1.0
Friendships satisfaction	0.4	0.4	1.4	-0.3	0.4	-1.0	-0.2	-0.5	-0.6	-1.2	-0.5
Qualifications: nursing, teaching	1.0	1.6	3.7	1.1	-0.3	-1.7	1.0	-0.8	-1.9	1.4	0.9
Commuting to job workplace: Walk	0.6	0.6	1.5	-1.0	0.6	-0.6	-1.2	0.1	-1.0	0.1	-0.8
Eye problems/disorders: Cataract	0.3	0.3	1.0	-0.3	0.2	-0.9	0.2	0.2	-0.2	-1.0	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.8	0.6	-0.1	2.0	0.2	0.3	1.9	-0.7	0.3
Medication for cholesterol	1.0	1.5	3.7	-1.9	-0.4	-1.0	-1.4	-1.3	-0.2	0.7	-1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.0	-0.6	0.4	-0.4	-0.9	-1.0	0.6	-0.6	-0.8
Back pain experienced in last month	1.0	1.4	3.2	-0.1	-1.2	1.6	-1.4	-0.4	1.8	-1.0	0.9
Mineral and other dietary supplements	1.3	1.7	8.1	-0.5	2.0	-0.4	-0.3	-0.3	-0.6	-2.9	-0.8
Breast cancer (self-reported)	0.3	0.4	0.8	-0.2	-0.6	-0.6	-0.4	0.9	-0.9	-0.5	-0.0
Asthma (self-reported)	0.8	1.7	6.4	-1.0	-1.1	-1.4	-0.5	-1.5	-2.5	-0.3	-0.6
Osteoporosis (self-reported)	0.3	0.4	1.7	-0.3	-0.1	0.7	-0.2	-0.4	-0.7	-1.3	0.2
Osteoarthritis (self-reported)	1.0	1.3	3.0	1.7	0.1	1.3	1.3	1.4	1.1	-0.6	0.3
Medication: Aspirin	0.2	0.3	0.8	-0.4	-0.2	0.8	-0.2	-0.9	0.5	0.1	0.5
Medication: Gliclazide	1.3	1.4	3.5	-0.7	1.1	1.5	-0.6	-0.8	1.9	1.6	-0.5
Illnesses of father: None of the above (group 1)	0.9	1.1	3.8	-1.2	-0.2	-1.2	-0.7	1.0	-1.9	-0.5	-0.8
Smoking status: Current	0.6	1.0	2.9	0.2	1.0	1.7	-0.2	1.5	0.6	0.4	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.2	9.9	0.3	1.6	1.7	0.5	3.1	0.5	-0.3	1.3
Whole body water mass	0.2	1.2	3.6	-0.8	0.7	0.4	-1.0	-1.9	-1.1	0.5	-1.4
Leg predicted mass (right)	0.2	1.1	3.8	-0.8	0.8	0.0	-0.9	-1.9	-0.8	-0.0	-1.6
Arm fat mass (left)	0.2	0.8	2.8	-0.5	-0.6	0.5	-0.4	-1.7	0.4	-0.7	-1.4
Number of self-reported non-cancer illnesses	0.7	1.2	7.1	0.2	-1.2	-0.0	0.6	-2.7	-0.5	0.1	0.6
Average weekly champagne plus white wine intake	1.0	1.4	5.5	1.0	-1.2	-2.4	0.9	-1.0	-0.5	1.1	0.0
Miserableness	0.6	1.1	4.5	0.1	1.3	1.2	-0.1	0.2	2.1	0.9	-0.7
Guilty feelings	1.2	1.8	3.3	-1.5	-0.5	1.4	-1.8	-1.7	-1.6	-0.9	-0.7
Wears glasses or contact lenses	1.1	1.3	2.8	-0.6	-1.2	-0.2	-1.4	-0.7	0.6	-1.7	-1.6
Ever taken oral contraceptive pill	0.6	0.7	1.6	-0.7	1.0	1.0	-0.8	1.3	-0.1	0.4	-0.8
Hearing aid user	1.3	1.4	3.1	0.4	-1.2	-0.9	0.7	-1.8	1.3	1.4	1.3
Mother’s age at death	0.7	0.8	2.3	1.2	0.4	-0.6	1.5	0.2	-0.2	1.4	0.5
Financial situation satisfaction	1.1	1.4	3.5	0.7	-0.4	-1.9	0.8	-1.8	1.6	-0.4	0.8
Tinnitus: Yes, now most or all of the time	1.4	1.6	6.0	1.4	-0.7	0.1	1.9	0.5	0.7	0.2	2.5
Commuting to job workplace: Public transport	1.7	2.0	5.0	-1.9	1.3	0.2	-1.9	1.0	-0.6	-0.7	-2.2
Eye problems/disorders: Glaucoma	0.5	0.6	1.4	-0.4	1.2	-0.3	0.5	1.0	-1.0	0.6	-0.4
Medication: Blood pressure	1.1	2.1	4.6	2.0	-1.5	0.3	2.2	0.0	0.8	-0.2	2.1
Pain type(s) experienced in last month: Hip pain	1.0	1.2	5.0	-0.8	-1.1	1.0	-1.3	-0.3	0.1	-2.2	-0.2
Supplements: Fish oil (including cod liver oil)	0.7	1.0	4.5	0.6	-1.4	-0.0	0.4	0.2	0.8	2.1	0.1
High cholesterol (Self-reported)	0.3	0.5	1.6	1.3	0.1	0.5	1.2	-0.7	-0.0	0.3	0.7
Medication: Bendroflumethiazide	1.7	2.6	5.8	2.4	-1.5	-0.7	2.4	-1.0	1.2	1.8	0.9
Medication: Paracetamol	3.1	4.8	13.6	2.1	0.1	0.4	3.0	0.9	3.7	1.8	2.7
Medication: Lisinopril	0.6	0.8	1.9	1.2	0.3	1.1	1.4	-0.2	1.1	-0.4	0.5
Medication: Atorvastatin	0.5	0.6	3.0	0.1	1.7	0.9	0.4	0.7	0.2	-0.0	-0.9
Illnesses of father: High blood pressure	0.5	0.6	1.8	1.3	0.4	-0.3	1.4	-0.2	-0.3	-0.7	0.4
Alcohol drinker status: Never	0.5	0.6	2.0	1.0	1.1	0.0	0.9	1.4	0.1	-0.0	0.3
Ever smoked	1.0	1.7	2.8	0.9	1.7	1.6	0.9	0.6	-1.3	1.6	1.6
Basal metabolic rate	0.2	1.1	3.9	-0.7	0.7	0.6	-0.9	-2.0	-0.8	0.3	-1.4
Leg fat percentage (left)	0.3	1.2	3.4	1.1	-0.8	1.9	1.2	-0.8	1.0	-1.1	-0.2
Arm fat-free mass (left)	0.2	1.0	2.4	-0.4	0.7	1.5	-0.8	-1.5	-0.7	0.6	-1.0
Number of operations (self-reported)	0.3	0.5	2.0	-0.0	-0.4	1.1	0.3	1.4	0.5	0.4	0.1
Average weekly beer plus cider intake	1.7	2.4	9.2	-2.1	1.0	0.9	-1.1	1.3	-0.5	-3.0	-1.0
Irritability	0.7	1.2	4.3	1.9	-0.6	1.1	2.1	0.5	-0.2	0.2	0.5
Risk taking	1.3	1.9	4.6	1.9	0.4	0.1	1.8	2.1	-0.4	0.8	1.7
Ever had prostate specific antigen (PSA) test	1.9	2.2	5.8	2.4	0.1	-0.3	2.4	-1.3	0.9	0.5	1.9
Fractured/broken bones in last 5 years	1.0	1.2	2.4	0.2	0.0	-1.3	1.0	1.4	1.6	0.9	1.4
Age started oral contraceptive pill	0.8	1.0	4.1	-1.4	-0.1	-0.2	-0.9	-0.4	-2.0	-0.8	-0.7
Diastolic blood pressure, automated reading	1.8	5.5	16.5	1.0	-4.1	-3.4	1.5	-3.2	-0.9	-1.1	-0.4
Ever depressed for a whole week	0.4	0.4	1.4	-0.5	-0.5	0.1	-0.7	-1.2	-0.1	0.9	-0.6
Unable to work because of sickness or disability	0.8	1.1	5.1	0.0	-0.8	2.2	-0.4	-0.5	1.1	-0.9	0.7
Commuting to job workplace: Cycle	1.9	2.3	7.7	-0.3	2.8	1.6	-0.4	2.0	-1.7	-1.1	-0.2
Myopia	0.6	0.9	1.7	0.4	0.8	1.3	0.6	1.1	-1.3	1.3	0.1
Vascular/heart problems diagnosed by doctor	0.9	2.3	4.7	-1.5	1.7	0.8	-2.2	2.0	-1.1	-0.9	-1.5
Cholesterol lowering medication	0.3	0.5	1.2	1.0	0.7	0.0	0.8	0.5	0.0	-1.1	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	3.6	-0.0	0.4	1.9	0.1	0.6	-0.8	-1.2	-0.4
Pain experienced in last month	1.4	2.4	5.5	-1.7	0.5	-0.6	-0.9	0.1	-2.1	2.1	-2.3
Supplements: Calcium	0.5	0.5	2.6	0.3	-0.8	-0.2	0.2	0.3	0.7	1.6	0.2
Basal cell carcinoma (self-reported)	0.2	0.3	1.0	0.4	-0.7	0.5	0.5	-0.1	-1.0	0.0	0.1
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.6	-1.6	0.1	0.1	-1.6	-0.7	-1.0	0.2	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.7	0.1	1.3	-1.0	0.0	0.4	0.7	-0.4	-1.6
Heart disease (siblings)	0.2	0.2	0.6	-0.0	0.6	0.0	0.0	-0.6	0.8	-0.7	-0.1
Alcohol drinker status: Previous	0.4	0.5	1.0	0.6	0.9	0.5	0.8	0.0	0.7	-1.0	0.0
Pack years of smoking	0.6	0.9	5.5	0.1	0.9	-0.0	0.5	0.2	0.1	-2.3	0.6
Impedance of whole body	0.2	1.2	5.8	0.0	-0.4	0.4	0.2	2.4	0.3	-1.4	1.0
Leg fat mass (left)	0.2	0.8	2.7	0.3	-0.4	1.6	0.3	-1.6	0.5	-0.7	-0.8
Arm predicted mass (left)	0.2	0.9	3.3	-0.4	0.4	1.2	-0.8	-1.8	-0.6	0.7	-0.9