TWAS hub - GFOD2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0230	0.0130	1.7e-03	0.010	0.006	0.008	0.003	0.010	0.01800	0.0610	3.4e-02	0.12	0.01900
2	GTEx	Cells EBV-transformed lymphocytes	0.1070	0.0710	8.1e-03	0.072	NA	0.019	NA	0.048	0.00230	NA	7.5e-02	NA	0.01100
3	GTEx	Esophagus Mucosa	0.0680	0.0280	2.2e-05	0.045	NA	0.064	NA	0.057	0.00055	NA	4.5e-05	NA	0.00011
4	GTEx	Skin Sun Exposed Lower leg	0.0480	0.0340	5.7e-03	0.004	NA	0.057	NA	0.027	0.14000	NA	1.6e-05	NA	0.00260
5	GTEx	Thyroid	0.1840	0.0810	1.6e-03	0.006	NA	0.020	NA	0.015	0.11000	NA	1.1e-02	NA	0.02300
6	TCGA	Breast Invasive Carcinoma	0.0196	0.0118	2.1e-03	0.000	0.009	0.006	NA	0.002	0.31000	0.0050	1.7e-02	NA	0.10000
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.0267	0.0152	3.9e-04	0.031	0.021	0.024	NA	0.028	0.00016	0.0016	9.4e-04	NA	0.00036
8	TCGA	Prostate Adenocarcinoma	0.0389	0.0222	1.9e-03	0.027	0.028	0.009	NA	0.017	0.00069	0.0006	3.4e-02	NA	0.00550
9	TCGA	Testicular Germ Cell Tumors	0.3700	0.1350	2.4e-03	0.007	0.003	0.004	NA	0.026	0.17000	0.2400	2.2e-01	NA	0.04200

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
HDL Cholesterol	51.7	86.2	151.3	-10.0	-11.2	-11.7	-10.2	3.5	-9.4	-0.3	-7.5	12.3
Lung FEV1/FVC ratio	11.8	59.6	102.5	-8.9	-8.6	-7.4	-5.5	5.6	-8.6	-7.8	-10.1	5.5
Medication: Seretide 50 evohaler	10.2	11.8	18.6	4.0	4.3	4.2	4.3	-0.4	3.3	1.8	4.1	-1.9
Blood Red Count	8.7	84.0	141.6	-11.2	-11.1	-10.4	-8.5	3.4	-9.0	-6.5	-11.9	7.1
Ovarian Cancer	7.8	10.4	17.7	3.5	3.7	3.5	3.7	-2.3	2.3	2.2	4.2	-2.9
Fasting Glucose	5.1	6.1	8.9	2.5	3.0	2.7	2.6	-1.0	3.0	2.0	2.5	-2.2
Hypothyroidism (self reported)	5.1	11.6	28.0	-3.3	-3.9	-2.5	-3.0	1.5	-3.7	-5.3	-4.4	-0.3
Hair/balding pattern: Pattern 4	4.8	11.7	42.1	3.5	2.6	0.3	1.2	0.5	5.1	6.5	4.1	-0.0
Frequency of tenseness / restlessness in last 2 weeks	4.6	7.2	16.6	-3.4	-3.5	-3.1	-2.3	0.3	-4.1	0.1	-2.7	1.5
Myopia	4.1	5.9	16.0	-3.1	-2.3	-1.5	-1.3	0.9	-2.5	-3.2	-4.0	1.2
Hypothyroidism/myxoedema (self-reported)	3.9	7.5	17.3	-2.7	-3.0	-2.0	-2.4	1.3	-3.1	-4.2	-3.5	-0.2
Fluid intelligence score	3.8	7.8	12.8	3.4	3.6	3.0	2.9	-1.1	3.2	1.2	2.9	-2.8
Emphysema/chronic bronchitis	3.7	4.2	9.8	2.0	2.1	2.6	2.1	-1.6	1.8	1.0	3.1	-1.4
Bipolar Disorder or Schizophrenia	3.6	8.9	17.6	-3.3	-3.5	-2.9	-3.4	-0.0	-2.9	-4.2	-3.3	0.0
Deep venous thrombosis (DVT) (self-reported)	3.6	4.6	8.7	-2.2	-2.8	-2.9	-2.3	2.3	-2.1	-0.4	-2.2	1.0
Primary Biliary Cirrhosis	3.5	5.0	12.1	-2.3	-3.0	-3.5	-2.5	0.8	-1.8	0.6	-1.4	2.5
Illnesses of father: High blood pressure	3.5	4.3	8.1	-2.7	-2.4	-2.1	-1.7	1.6	-1.8	-1.6	-2.8	1.6
Schizophrenia (2018)	3.3	6.8	11.0	-2.9	-3.3	-2.8	-2.9	-0.5	-3.0	-3.0	-2.7	0.0
Irritability	3.3	5.7	11.3	-2.8	-2.9	-2.5	-1.8	1.1	-3.4	-0.9	-2.3	2.6
Schizophrenia (2014)	3.1	6.9	12.0	-2.9	-3.5	-3.3	-3.2	-0.3	-3.0	-2.2	-2.7	0.0
Birth weight	3.1	6.8	11.4	2.7	3.0	3.3	2.6	-3.4	1.9	1.6	3.0	-0.8
Blood clot in the leg (DVT)	2.9	3.7	7.3	-2.0	-2.5	-2.7	-2.1	1.9	-1.8	-0.3	-1.9	0.9
Supplements: Zinc	2.8	3.0	5.8	-2.2	-1.9	-1.7	-2.1	0.8	-2.4	-1.1	-1.7	1.1
Stomach or abdominal pain in last month	2.8	3.5	6.7	-2.6	-2.5	-2.4	-1.4	1.4	-2.0	-0.7	-1.4	1.6
Ever highly irritable/argumentative for 2 days	2.8	3.4	10.4	-1.3	-1.9	-2.4	-1.4	-0.5	-0.9	3.2	1.2	2.2
Average weekly spirits intake	2.7	3.3	5.3	2.1	2.1	2.0	1.9	-0.9	1.9	1.7	2.3	-1.0
Suffer from ‘nerves’	2.7	4.2	10.8	-2.4	-2.5	-1.6	-1.1	0.1	-3.3	-2.2	-1.9	1.4
Intelligence (Savage-Jansen 2018)	2.6	8.1	15.0	3.3	3.9	3.5	2.6	-0.7	3.8	0.3	2.4	-2.7
Lupus	2.6	3.9	10.6	-2.3	-2.5	-2.5	-1.6	-0.1	-1.5	-0.8	-1.4	3.2
Forced vital capacity (FVC)	2.6	10.0	16.5	3.6	3.6	2.7	2.1	-2.6	4.1	3.3	2.4	-3.6
Number of full brothers	2.6	3.3	6.0	2.4	2.5	2.0	1.7	-0.0	2.1	1.0	2.2	-1.0
Basal cell carcinoma (self-reported)	2.6	3.0	5.6	2.1	2.4	2.1	2.1	-0.9	1.8	-0.0	1.1	-1.8
Pain type(s) experienced in last month: Hip pain	2.5	3.1	7.8	-2.1	-1.9	-1.4	-1.7	0.7	-2.8	-1.3	-1.7	1.4
Verbal and Numeric Reasoning (VNR)	2.4	5.9	10.5	2.9	3.2	2.8	2.6	-0.4	2.8	0.1	2.0	-2.7
Qualifications: CSEs or equivalent	2.4	3.1	7.8	-1.8	-1.4	-1.0	-1.4	1.0	-2.0	-2.7	-2.8	0.0
Falls in the last year	2.4	3.2	5.0	1.7	1.6	2.1	1.4	-2.2	2.0	1.4	2.1	-1.1
Heart attack/myocardial infarction (self-reported)	2.4	3.1	6.4	-2.0	-2.0	-2.0	-1.6	-0.8	-2.5	-0.2	-1.6	2.0
Prostate Cancer	2.3	3.2	5.7	2.4	1.8	1.6	2.3	-0.9	1.4	1.1	2.4	-1.6
Lung FVC	2.3	11.6	21.8	4.1	4.5	3.6	3.5	-1.3	4.7	0.7	3.0	-3.2
Hair/balding pattern: Pattern 3	2.3	3.4	8.0	1.6	1.8	2.7	1.6	-1.1	0.6	-2.3	0.0	-2.8
Average weekly champagne plus white wine intake	2.3	3.1	10.9	-1.2	-1.8	-1.9	-1.1	3.3	-1.1	-1.1	-1.4	1.7
Medication: Levothyroxine sodium	2.2	3.7	16.4	-1.3	-1.4	-0.5	-1.0	1.2	-2.0	-4.0	-2.3	-1.3
Ever unenthusiastic/disinterested for a whole week	2.2	2.6	6.3	-2.1	-2.5	-2.0	-0.8	0.1	-1.6	-0.4	-1.6	1.8
Migraine (self-reported)	2.2	2.8	5.1	-1.8	-1.4	-1.9	-1.8	2.2	-0.9	-0.8	-2.2	1.4
Chest pain or discomfort	2.2	3.2	8.0	1.9	1.6	2.2	2.0	-0.4	0.8	0.7	2.8	-2.2
Mood swings	2.2	3.9	7.9	-2.4	-2.6	-2.3	-1.9	-0.2	-2.8	-0.9	-2.1	1.0
Pain experienced in last month	2.2	3.7	5.4	2.1	2.2	2.3	2.1	-2.0	2.1	-0.7	1.3	-1.8
Depression (Nagel 2018)	2.1	3.2	5.6	-2.3	-2.3	-2.4	-1.2	-0.3	-2.3	0.4	-1.2	2.1
Coronary Artery Disease (CAD)	2.1	2.5	5.2	1.8	1.7	1.6	2.3	-0.0	1.6	0.8	1.5	-1.7
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	5.7	1.9	1.7	1.5	1.0	-0.4	1.4	2.4	2.0	-0.8
Tense / ‘highly strung’	2.1	3.5	7.3	-2.3	-2.4	-2.2	-1.4	-0.2	-2.7	-0.0	-1.7	1.7
Forced vital capacity (FVC), Best measure	2.1	7.5	13.5	3.2	3.3	2.3	2.0	-1.7	3.7	2.4	2.1	-3.2
Worry (Nagel 2018)	2.0	4.2	9.0	-2.7	-2.8	-2.3	-1.6	-0.5	-3.0	-0.9	-2.0	0.9
Neuroticism	2.0	4.9	13.9	-2.7	-2.6	-2.4	-1.6	0.1	-3.7	-0.7	-2.3	1.2
Chronotype (morning person)	2.0	4.7	6.9	2.6	2.6	2.0	0.7	-1.1	2.6	2.6	2.0	-2.3
Serious illness, injury or assault to yourself	2.0	2.4	6.9	1.3	1.1	0.8	0.1	-1.7	1.8	2.6	1.9	-1.1
Heart attack	2.0	2.6	5.3	-1.9	-1.8	-1.7	-1.5	-0.9	-2.3	-0.3	-1.4	1.9
Osteoporosis (self-reported)	2.0	2.4	6.1	1.7	1.6	1.8	2.2	-0.2	0.4	0.3	1.4	-2.5
Crohns Disease (2017)	1.9	4.2	9.6	2.3	2.1	2.2	0.2	-3.1	2.7	0.6	0.8	-2.4
Neuroticism (2016)	1.9	2.8	5.3	-1.9	-2.3	-2.2	-1.1	0.2	-2.3	-0.3	-1.4	1.6
Frequency of depressed mood in last 2 weeks	1.9	2.6	4.5	-2.1	-2.1	-1.9	-0.9	-0.2	-2.1	-0.3	-1.4	1.9
Alcohol usually taken with meals	1.9	3.1	8.4	-1.9	-1.7	-1.2	-1.2	0.8	-1.8	-2.9	-2.2	1.0
Had other major operations	1.9	2.4	3.7	-1.9	-1.8	-1.4	-1.4	1.3	-1.9	-0.5	-1.8	1.4
Prospective memory result	1.9	2.4	4.0	-1.6	-1.9	-1.8	-2.0	1.5	-1.5	-0.4	-1.4	1.2
Neuroticism (Nagel 2018)	1.8	4.2	10.4	-2.5	-2.7	-2.5	-1.7	0.1	-3.2	-0.5	-1.9	0.9
Waist Hip Ratio (WHR)	1.8	8.3	33.4	2.7	2.0	0.8	0.9	-1.1	2.4	5.8	4.7	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.3	6.8	-1.8	-2.1	-1.9	-1.0	-0.1	-2.6	-0.1	-1.0	1.1
Qualifications: College or University degree	1.8	5.7	14.7	2.9	2.7	2.4	0.6	-1.8	3.8	1.8	1.8	-2.4
Neck or shoulder pain in last month	1.8	2.5	4.4	-1.8	-2.1	-1.8	-1.7	0.7	-1.6	-0.7	-1.5	1.8
Loneliness, isolation	1.8	2.5	6.1	-1.7	-1.8	-1.8	-1.4	1.1	-2.5	0.1	-1.3	1.4
Medication: Blood pressure	1.8	3.5	12.5	-1.5	-1.6	-2.6	-0.7	2.5	0.4	0.2	-0.6	3.5
Schizophrenia vs Biploar Disorder	1.7	2.3	6.1	-1.1	-1.7	-2.2	-2.5	1.0	-1.8	0.1	-1.1	0.0
Bilateral oophorectomy (both ovaries removed)	1.7	2.0	5.0	-1.6	-1.5	-2.2	-1.2	1.7	-0.5	-0.7	-1.4	0.7
Neuroticism score	1.7	3.6	12.9	-2.4	-2.4	-1.7	-1.2	-0.0	-3.6	-0.6	-1.7	0.6
Illnesses of mother	1.7	2.1	5.6	1.5	1.5	2.3	1.2	-0.6	1.0	-0.8	0.4	-2.4
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	6.7	-1.7	-1.6	-1.6	-2.6	0.6	-1.1	0.3	-1.4	1.5
Headache pain in last month	1.7	3.0	5.0	-2.0	-1.8	-2.2	-1.9	2.0	-1.5	0.5	-1.0	1.9
Shortness of breath walking on level ground	1.7	2.0	4.6	1.7	1.2	1.2	1.8	0.9	1.1	1.3	2.1	-0.5
Ever depressed for a whole week	1.7	2.1	4.5	-1.5	-2.1	-2.0	-1.3	1.3	-0.7	0.2	-0.9	1.7
Bipolar Disorder (2018)	1.6	2.6	8.7	-1.6	-1.5	-1.1	-2.0	0.8	-0.9	-2.9	-1.8	0.0
Alzheimer’s Disease (in father)	1.6	1.8	4.3	-1.7	-1.2	-0.9	-1.4	-0.3	-2.1	-1.4	-1.6	0.1
Allergy or Eczema	1.6	4.2	9.1	2.1	2.5	3.0	2.2	-0.3	1.6	-0.3	2.2	-2.3
Diabetes (mother)	1.6	2.0	8.1	-1.1	-1.9	-1.5	-0.4	-0.9	-2.8	0.4	-0.3	1.4
Supplements: Glucosamine	1.6	2.1	3.7	1.8	1.5	1.4	-0.6	-0.4	1.9	1.6	1.7	-1.5
Nervous feelings	1.6	3.1	6.9	-2.2	-2.1	-1.2	-0.9	-0.9	-2.6	-1.9	-2.1	-0.0
Time employed in main current job	1.6	1.9	4.1	-1.5	-1.3	-0.4	-0.6	-1.3	-1.9	-2.0	-1.7	-0.1
Medication: Cholesterol lowering	1.6	2.5	4.3	-2.1	-2.0	-2.0	-1.7	-0.4	-1.9	-0.7	-1.0	1.3
Eye problems/disorders: None of the above	1.6	1.8	4.3	1.3	1.8	2.1	1.1	-0.8	1.3	0.3	0.7	-1.7
Medication for cholesterol	1.6	2.4	7.5	0.8	1.0	2.0	0.4	-2.4	-1.1	-1.0	-0.3	-2.7
Number of treatments/medications taken	1.5	2.6	11.0	-1.3	-1.6	-1.9	-0.6	1.8	-0.8	0.7	0.1	3.3
Medication: Atenolol	1.5	1.9	3.9	-1.2	-1.1	-2.0	-1.7	0.7	1.1	1.0	-0.9	2.0
Medication: Lisinopril	1.5	1.9	3.6	1.5	1.8	0.7	1.6	0.6	1.5	1.9	1.7	-0.1
Financial difficulties in last 2 years	1.4	1.8	5.9	-0.8	-0.6	-1.6	-0.5	1.1	-0.9	2.4	-0.5	2.2
Chronic bronchitis/emphysema (mother)	1.4	1.6	4.7	-0.8	-0.4	-0.3	1.6	1.1	-2.2	-1.2	-0.5	1.9
Smoking status: Previous	1.4	2.1	8.4	-1.5	-1.2	-0.3	-0.7	-1.5	-1.2	-2.9	-1.4	0.7
Eye problems/disorders: Cataract	1.4	1.6	3.5	-1.4	-1.4	-1.6	-0.9	1.9	-1.0	-0.8	-0.8	1.0
Asthma (self-reported)	1.4	2.8	6.4	1.7	2.2	2.5	2.2	-1.3	1.2	-0.3	1.7	-0.1
Alcohol drinker status: Previous	1.4	1.6	7.0	-1.0	-1.4	-1.1	0.6	-0.6	-1.6	-0.2	-0.3	2.6
Triglycerides	1.3	2.1	4.6	1.3	1.7	1.5	1.6	-1.5	1.4	0.1	0.7	-2.2
Respiratory disease	1.3	2.9	7.2	1.9	2.2	2.7	2.1	-0.7	1.3	-0.3	1.8	-0.9
Multivitamins +/- minerals	1.3	1.7	3.7	-1.4	-1.6	-1.2	-1.9	0.1	-1.7	-1.1	-1.2	-0.0
Pulse wave peak to peak time	1.3	1.5	4.8	0.9	1.6	2.2	0.6	-0.8	1.5	0.2	1.4	-0.8
Age at First Birth	1.2	1.8	3.3	1.2	1.8	1.7	0.9	-1.0	1.8	-1.1	0.4	-1.3
Crohns Disease (2012)	1.2	1.9	3.2	1.7	1.4	1.2	-0.2	-1.3	1.8	0.9	1.6	-1.4
Medication: Co-codamol	1.2	1.4	2.3	-1.0	-1.5	-0.9	-1.1	1.4	-1.2	-1.1	-1.3	0.8
Alcohol intake versus 10 years previously	1.2	1.8	8.8	1.2	0.8	0.2	-0.1	-0.6	1.2	3.0	1.8	-0.0
Happiness	1.2	1.5	4.7	1.3	0.9	0.4	0.7	-0.7	1.5	2.2	1.5	0.8
Asthma	1.2	2.4	5.4	1.4	2.0	2.3	2.1	-1.4	1.0	-0.5	1.5	0.2
Standing height	1.2	12.1	48.7	2.8	1.9	0.8	-0.7	-5.0	3.7	7.0	1.6	-2.7
Comparative body size at age 10	1.2	3.3	9.7	-0.8	-1.5	-1.8	-3.1	2.2	-0.5	1.5	-1.1	2.2
Alcohol intake frequency.	1.2	2.8	5.3	-1.7	-2.0	-1.5	-0.5	1.0	-2.3	-1.2	-1.6	2.3
Had major operations	1.2	1.4	2.4	1.2	1.3	1.1	1.0	1.0	1.1	1.4	1.5	-0.8
Supplements: Vitamin C	1.2	1.4	2.9	-1.5	-1.4	-0.7	-1.0	0.3	-1.1	-1.4	-1.0	1.7
Ever smoked	1.2	2.0	3.3	-1.7	-1.8	-1.5	-1.7	0.2	-1.2	-1.2	-1.1	1.7
Blood Eosinophil Count	1.1	8.4	16.6	-1.8	-3.0	-3.7	-1.4	3.9	-4.1	3.1	0.7	2.3
Heel T-Score	1.1	8.7	31.2	-1.9	-1.2	0.9	-1.2	-5.4	-0.8	-5.6	-2.8	1.5
Vitamin and mineral supplements	1.1	1.4	3.6	1.4	1.5	0.8	1.4	0.2	1.9	1.2	0.8	-0.8
Pack years adult smoking proportion	1.1	1.7	3.9	1.6	1.1	0.7	1.6	-0.6	1.0	1.9	2.0	0.1
Comparative height size at age 10	1.1	6.2	33.9	1.5	0.2	-1.1	-0.7	-2.6	2.7	5.8	1.9	0.4
Number of full sisters	1.1	1.4	3.3	1.1	0.9	-0.0	0.2	0.5	1.6	1.8	1.8	1.1
Back pain experienced in last month	1.1	1.6	5.2	-1.2	-1.7	-1.5	-2.3	-0.1	-1.0	0.8	-0.6	0.9
Medication: Bendroflumethiazide	1.1	1.6	4.6	0.6	0.6	-0.8	0.2	1.6	2.2	1.4	1.1	1.6
Commuting to job workplace: Cycle	1.1	1.4	2.7	-1.6	-1.0	-1.0	-1.6	-0.2	-1.1	-0.1	-1.1	1.6
Pack years of smoking	1.1	1.7	3.9	1.6	1.1	0.8	1.5	-0.3	1.0	1.8	2.0	0.1
Type 2 Diabetes (T2D) (2012)	1.0	1.1	2.1	1.1	1.0	1.1	0.8	0.0	1.3	-1.3	0.5	-1.5
Diabetes (father)	1.0	1.2	3.0	-1.1	-1.5	-1.5	-1.7	0.7	-0.9	-0.1	-1.0	0.2
High blood pressure (mother)	1.0	1.4	3.9	-1.5	-1.4	-1.6	-0.2	0.7	-0.5	-0.6	-0.6	2.0
Number of incorrect matches in round	1.0	1.6	6.2	-1.3	-1.4	-1.5	0.2	0.3	-0.9	1.2	0.2	2.5
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.4	14.4	0.4	0.7	1.8	0.1	-3.8	0.6	-1.5	-0.1	-0.9
Pulse wave Arterial Stiffness index	1.0	1.1	4.6	-0.5	-1.3	-2.1	-0.6	0.4	-1.0	0.6	-1.1	0.7
Family relationship satisfaction	1.0	1.2	5.1	0.8	0.5	0.2	-0.0	-1.8	0.6	2.3	0.8	0.5
Knee pain experienced in last month	1.0	1.6	4.7	-1.2	-1.1	-1.2	-1.4	0.2	-2.2	0.5	-1.3	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	2.3	1.3	1.2	0.9	0.9	-0.1	1.4	1.1	1.5	-0.0
Qualifications: nursing, teaching	1.0	1.6	3.1	-1.8	-1.3	-1.1	-1.1	0.1	-1.2	-1.5	-1.6	0.9
Mineral and other dietary supplements	1.0	1.3	4.0	-1.2	-0.9	-1.4	1.2	0.2	-0.8	-0.5	-1.0	2.0
Osteoarthritis (self-reported)	1.0	1.3	2.3	-1.4	-1.5	-1.5	-1.1	0.4	-1.1	-0.8	-1.1	0.9
Medication: Gliclazide	1.0	1.1	2.0	-1.3	-1.1	-0.7	-1.2	0.4	-1.3	-1.0	-1.4	-0.6
High cholesterol (Self-reported)	1.0	1.8	4.4	-1.4	-1.7	-2.1	-0.6	1.0	-1.1	-0.5	-0.0	2.1
Ulcerative Colitis (UC)	0.9	1.8	5.4	-1.3	-1.3	-1.6	-1.7	-0.9	-0.8	0.0	-0.6	2.3
Trunk fat percentage	0.9	3.8	7.5	-1.1	-2.1	-2.7	-2.4	2.6	-0.3	2.2	-0.0	1.9
Impedance of leg (left)	0.9	4.5	16.6	-0.7	-2.0	-2.8	-1.4	-1.0	-0.8	4.1	1.8	2.2
Hair/balding pattern: Pattern 2	0.9	1.2	4.9	-1.2	-1.1	-1.1	-2.2	-0.1	-0.1	-0.1	-1.3	0.5
Trunk fat-free mass	0.9	5.2	9.9	2.3	2.4	2.2	0.4	-2.7	3.1	2.6	-0.3	-2.6
Qualifications: A levels/AS levels or equivalent	0.9	2.0	3.4	1.6	1.5	1.4	1.4	-1.8	1.6	0.6	0.8	-1.6
Trunk predicted mass	0.9	5.3	10.4	2.4	2.5	2.2	0.5	-2.7	3.2	2.6	-0.2	-2.5
Number of children fathered	0.9	1.0	2.0	1.2	1.4	1.3	1.2	-0.5	1.0	-0.1	0.5	-1.2
Illness, injury, bereavement, stress in last 2 years	0.9	1.2	4.1	0.8	0.6	1.2	-0.5	-0.3	0.7	-2.0	-0.1	-1.7
Illnesses of siblings: Diabetes	0.9	1.2	7.0	0.4	0.7	0.8	2.6	0.5	-0.6	-0.4	0.9	0.8
Depressed Affect (Nagel 2018)	0.8	1.7	5.3	-1.4	-1.7	-1.6	-1.1	0.5	-2.3	-0.2	-0.9	0.5
Breast Cancer	0.8	2.0	3.6	1.6	1.7	1.8	1.5	-1.0	0.8	1.2	1.9	-0.1
Hearing difficulty/problems: Yes	0.8	1.2	2.6	0.9	1.0	1.5	1.6	-1.0	0.7	-0.8	1.3	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	11.9	0.2	0.4	1.4	-0.2	-3.5	0.5	-1.5	-0.3	-0.1
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.0	1.0	0.7	1.0	1.2	-1.0	0.1	1.4	1.4	-1.0
Birth weight of first child	0.8	1.4	7.5	0.3	0.2	1.1	-1.0	-2.7	-0.6	-1.2	-0.1	-1.1
Peak expiratory flow (PEF)	0.8	1.8	9.5	-0.7	-0.3	-0.8	-0.3	1.0	-0.2	-1.0	-3.1	-1.9
Medication: Amlodipine	0.8	1.1	3.5	-0.8	-0.0	0.1	1.7	-0.2	-0.9	-1.9	-1.2	0.8
Body fat percentage	0.8	3.2	7.8	-0.9	-1.7	-2.4	-2.0	2.8	-0.2	2.0	0.0	1.9
Wheeze or whistling in the chest in last year	0.8	1.5	5.7	1.0	1.0	1.5	2.4	-0.5	0.1	0.6	1.5	-0.4
Medication: Blood pressure	0.8	1.4	4.4	1.1	1.6	1.0	2.1	-0.6	1.4	0.6	1.0	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	4.7	-0.6	-0.5	0.2	0.1	0.4	-0.9	-2.2	-1.1	0.6
Average weekly red wine intake	0.8	1.1	3.4	0.8	1.1	1.9	0.1	-0.7	0.1	-0.1	1.1	-1.8
Commuting to job workplace: Public transport	0.8	1.0	3.3	1.3	0.8	0.6	0.3	-0.0	1.8	0.2	1.5	0.5
Supplements: Fish oil (including cod liver oil)	0.8	1.1	5.7	0.4	0.5	1.4	-0.8	-0.2	-0.7	-0.6	0.0	-2.4
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.6	-0.0	-0.4	-1.0	0.4	1.8	-0.1	1.9	0.2	0.9
Impedance of whole body	0.8	4.0	11.4	-1.1	-2.3	-3.0	-1.5	-0.3	-1.3	3.4	1.7	1.6
Mean Putamen Volume	0.7	0.8	2.1	0.6	0.3	1.0	1.3	-0.2	0.1	-1.4	0.2	-1.3
Height	0.7	13.9	69.9	2.5	1.5	0.3	-1.4	-5.0	3.0	8.4	1.9	-2.8
Impedance of leg (right)	0.7	3.6	17.9	0.1	-1.1	-1.9	-0.6	-1.9	-0.4	4.2	2.2	0.8
Townsend deprivation index at recruitment	0.7	1.0	2.7	1.2	0.7	1.5	1.2	0.6	0.2	-0.3	1.6	-0.4
Current tobacco smoking	0.7	1.2	7.0	0.9	0.4	-0.5	-0.2	0.8	0.3	2.6	1.2	0.1
Sitting height	0.7	5.1	27.6	0.7	0.4	0.5	-0.7	-5.2	1.9	1.6	-1.8	-2.8
Chronic bronchitis/emphysema (father)	0.7	0.8	4.4	0.7	0.5	0.4	0.3	-2.1	0.2	1.0	1.0	-0.1
Waist circumference	0.7	2.7	11.8	1.6	1.1	0.3	0.4	0.6	2.2	3.4	1.7	0.7
Medication: Simvastatin	0.7	1.1	2.9	-1.0	-1.4	-1.7	-1.5	-0.2	-0.0	0.6	0.3	1.0
Illnesses of siblings	0.7	1.0	4.0	-0.9	-1.0	-0.3	-2.0	-0.4	-1.0	-0.6	-1.3	-0.1
Impedance of arm (right)	0.7	3.4	8.1	-1.2	-2.3	-2.9	-1.9	0.5	-1.4	2.5	1.1	1.6
Impedance of arm (left)	0.7	3.2	7.8	-1.4	-2.3	-2.8	-1.8	0.7	-1.6	2.2	1.0	1.2
Breastfed as a baby	0.7	0.8	2.6	0.6	0.8	0.6	0.9	1.3	0.8	-1.6	-0.0	-0.7
Worry too long after embarrassment	0.7	1.2	3.8	-1.5	-1.4	-0.9	-0.4	-0.9	-2.0	-0.1	-1.1	0.4
Medication: Ibuprofen	0.7	0.8	3.0	-0.9	-0.9	-0.7	-0.2	1.0	-1.1	0.0	-0.1	1.7
Medication: Omeprazole	0.7	0.8	3.5	-0.4	-0.7	-1.1	-0.0	1.0	-0.3	1.9	0.0	0.8
Leg pain on walking	0.7	0.9	3.2	1.1	0.5	0.4	0.6	0.2	0.6	1.5	1.8	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.3	0.9	1.1	0.6	-0.6	-0.3	0.8	1.8	-0.2	-0.4
Commuting to job workplace: Car/motor vehicle	0.7	0.8	4.4	0.4	0.9	0.8	2.1	-1.1	0.3	0.2	0.6	0.1
Medication: Aspirin	0.7	1.0	2.4	-0.8	-1.3	-1.3	-0.8	0.6	-1.0	0.5	-0.0	1.5
Smoking status: Current	0.7	1.1	5.9	0.9	0.3	-0.6	-0.2	0.9	0.2	2.4	1.3	0.3
Leg fat percentage (left)	0.7	2.5	6.6	-0.7	-1.3	-1.9	-1.4	2.6	-0.1	1.9	0.2	2.1
Average weekly beer plus cider intake	0.7	1.1	2.9	0.9	0.9	0.8	0.1	-0.6	1.0	1.6	1.7	-0.7
Cholesterol lowering medication	0.7	1.1	3.3	0.2	-0.4	-1.1	0.5	1.6	0.5	0.9	1.1	1.8
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.7	-0.4	-0.2	0.3	1.5	0.0	-0.6	-0.0	0.6	1.6
Trunk fat mass	0.6	2.4	8.4	-0.3	-1.1	-1.9	-2.0	1.8	0.6	2.9	0.0	1.0
Mouth/teeth dental problems	0.6	0.9	2.9	0.5	0.5	-0.8	-0.2	1.7	1.4	1.2	0.4	0.3
Arm fat percentage (right)	0.6	2.3	10.9	-0.8	-1.2	-1.6	-1.1	3.3	-0.2	0.6	-0.5	1.9
Father’s age at death	0.6	0.8	2.0	-0.8	-0.8	-0.6	-0.7	0.8	-0.7	-1.3	-1.4	-0.7
Medication: Paracetamol	0.6	1.0	5.6	0.5	-0.0	-0.3	-0.4	0.2	0.7	2.4	1.4	0.7
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.2	0.6	0.9	1.5	1.2	-0.0	0.1	-0.9	0.7	-0.9
Medication for pain relief, constipation, heartburn	0.6	1.1	3.1	0.4	0.8	0.9	0.1	-0.9	0.6	-1.6	-1.2	-1.8
Mean time to correctly identify matches	0.6	1.1	5.2	-1.1	-0.6	-0.9	0.9	1.0	-0.3	-0.1	-0.5	2.3
Arm fat percentage (left)	0.6	2.5	12.6	-0.8	-1.2	-1.6	-1.3	3.5	-0.2	0.7	-0.4	1.6
Breast cancer (self-reported)	0.6	0.7	1.6	-0.5	-0.2	-0.3	0.8	1.3	-1.1	-1.2	-0.5	-0.5
Hearing aid user	0.6	0.7	1.7	1.1	1.3	1.2	0.3	-0.1	0.4	0.3	0.8	-1.1
Mother’s age at death	0.6	0.8	1.9	-1.0	-1.2	-1.4	-1.2	-0.6	-0.5	0.2	-0.8	-0.3
Alcohol drinker status: Never	0.6	0.7	2.2	-0.9	-0.6	-0.2	0.2	-0.1	-1.5	-0.5	-1.2	-1.1
Arm fat-free mass (left)	0.6	2.9	7.4	1.7	1.7	1.3	0.0	-1.9	2.7	2.4	-0.5	-1.3
Number of operations (self-reported)	0.6	0.9	2.5	-0.9	-1.2	-1.0	-0.8	1.6	0.1	-0.4	-0.5	1.0
Irritable Bowel Disease (IBD)	0.5	1.2	7.3	0.6	0.6	0.4	-0.7	-2.7	1.2	0.6	0.3	0.1
Blood White Count	0.5	3.7	13.0	1.5	0.7	-0.8	0.4	1.4	1.8	3.6	3.4	0.4
Hair Pigment	0.5	14.8	22.4	-4.7	-4.2	-3.6	-3.6	2.1	-3.8	-3.3	-4.7	3.8
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.1	0.8	0.4	0.3	0.2	-0.7	1.5	0.7	1.2	-0.3
Fed-up feelings	0.5	1.0	4.4	-1.0	-1.1	-0.9	0.7	0.4	-2.1	-0.3	-0.7	0.4
Hayfever, allergic rhinitis or eczema	0.5	1.1	3.1	0.6	1.0	1.8	1.4	0.4	0.0	-1.2	0.6	-1.2
Qualifications: None of the above	0.5	1.0	4.7	0.4	-0.0	-0.3	0.8	0.5	0.1	1.5	2.2	0.7
Pain all over the body in last month	0.5	0.5	1.5	-0.4	-0.3	-0.5	1.0	1.2	-1.0	0.4	-0.4	0.3
Number of live births	0.5	0.8	1.5	-0.7	-0.8	-1.1	-1.2	1.1	-1.2	-0.2	-0.6	0.1
Pulse rate	0.5	0.9	2.9	-0.8	-0.9	-1.0	-0.4	1.0	-0.7	1.7	0.7	1.0
Lung cancer (father)	0.5	0.6	1.8	-0.9	-0.8	-0.8	-0.3	1.3	-0.4	-1.0	-0.3	0.1
Glaucoma (self-reported)	0.5	0.6	1.7	0.9	0.4	-0.3	0.7	-0.4	1.3	1.1	1.0	0.1
Arm fat-free mass (right)	0.5	2.4	5.5	1.4	1.5	1.3	-0.3	-1.7	2.3	2.0	-0.6	-1.8
Mouth/teeth dental problems: Loose teeth	0.5	0.5	1.4	-0.9	-0.9	0.1	-0.4	-0.4	-1.2	-1.0	-0.4	0.6
Whole body fat mass	0.5	2.1	6.2	-0.4	-1.1	-1.8	-1.7	1.9	0.5	2.5	-0.3	1.2
Age at last live birth	0.5	0.7	2.3	-0.8	-0.6	-1.2	-1.5	0.0	0.0	0.7	-0.3	0.7
Whole body fat-free mass	0.5	3.0	6.4	1.6	1.7	1.6	-0.2	-1.9	2.5	2.0	-0.7	-2.0
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.5	0.6	0.6	0.6	1.2	-0.8	0.4	0.8	1.1	0.2
Friendships satisfaction	0.5	0.6	1.7	0.9	0.6	0.5	0.2	-1.2	0.5	1.3	0.3	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.6	-0.0	-0.1	0.3	0.8	-0.7	-0.2	1.2	1.6	0.6
Illnesses of father: None of the above (group 1)	0.5	0.6	1.2	1.0	1.1	0.7	0.9	1.0	0.8	0.0	0.7	-0.2
Whole body water mass	0.5	2.8	6.1	1.6	1.7	1.6	-0.2	-1.9	2.5	1.8	-0.8	-1.9
Wears glasses or contact lenses	0.5	0.6	3.5	-0.6	-0.7	-0.5	0.4	0.7	0.3	0.1	0.1	1.9
Ever taken oral contraceptive pill	0.5	0.6	2.8	-0.0	0.1	0.9	-0.3	-1.7	-0.4	-1.0	-0.1	-0.3
Financial situation satisfaction	0.5	0.7	3.5	0.4	0.2	0.1	0.1	-0.9	0.1	1.9	1.0	0.7
Basal metabolic rate	0.5	2.7	6.2	1.6	1.6	1.3	-0.3	-1.5	2.5	2.3	-0.5	-1.7
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.1	-0.1	0.1	0.8	0.8	-1.0	0.0	-1.5	0.7	-0.4
Leg fat mass (left)	0.5	1.9	5.3	-0.3	-0.7	-1.5	-1.5	1.9	0.6	2.3	-0.4	1.4
Arm predicted mass (left)	0.5	2.7	7.2	1.5	1.6	1.2	-0.2	-1.9	2.7	2.3	-0.5	-1.2
Alzheimer’s Disease (including proxy)	0.4	0.6	1.7	-0.8	-0.8	-1.3	-0.7	0.4	-1.3	0.2	-0.4	-0.1
Major Depression (MDD)	0.4	0.5	1.8	-0.2	-0.4	-0.8	-0.8	1.1	-0.1	-1.3	-0.3	0.2
Reaction Time	0.4	0.8	3.6	-0.8	-0.4	-0.9	0.5	0.7	0.1	0.9	-0.2	1.9
Ulcerative Colitis	0.4	0.6	1.4	-0.6	-0.5	-0.8	-0.9	-1.2	-0.3	0.3	-0.2	1.1
Smoking Status	0.4	1.0	2.2	-1.0	-1.2	-1.4	-1.1	-0.2	-1.5	-0.1	-1.0	0.3
Sensitivity / hurt feelings	0.4	0.7	2.1	-0.8	-0.9	-1.3	-0.4	-0.6	-0.6	1.4	-0.2	0.5
Medication for hormone replacement therapy	0.4	0.5	1.3	-0.3	-0.2	-0.7	-0.8	1.1	0.6	0.5	0.2	1.1
Severe depression (siblings)	0.4	0.4	1.3	-0.2	-0.5	-0.3	-0.4	1.1	-1.2	-0.1	-0.6	-0.4
Maternal smoking around birth	0.4	0.5	2.7	-0.1	0.0	-0.1	-0.5	-1.6	0.0	1.3	0.1	0.3
Relative age voice broke	0.4	0.6	2.0	0.5	0.6	0.6	-0.8	1.4	0.6	-1.0	0.1	0.6
Taking other prescription medications	0.4	0.7	2.7	-0.7	-1.1	-0.5	0.1	-0.6	-0.8	-0.5	-0.2	1.6
High blood pressure	0.4	1.0	2.2	0.1	0.3	-0.7	1.3	1.2	1.4	0.8	0.9	1.5
Past tobacco smoking	0.4	0.8	2.0	0.9	0.9	0.5	0.8	1.2	0.6	1.4	0.5	-0.7
Noisy workplace	0.4	0.5	1.4	-0.7	-0.8	-0.6	-1.2	0.2	-0.9	-0.0	-0.1	0.9
Mouth/teeth dental problems: Dentures	0.4	0.7	2.9	0.3	0.1	0.7	1.5	-0.4	-0.2	0.1	1.7	-0.3
Pulse wave reflection index	0.4	0.5	1.4	-0.4	-0.5	-1.1	-1.1	-0.4	-0.2	-0.6	-1.2	0.2
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.6	0.4	0.3	0.7	0.3	-0.9	0.1	-0.9	-0.3	-1.6
Gout (self-reported)	0.4	0.5	2.2	-0.3	-0.0	0.4	0.3	1.0	-1.0	-1.5	-0.2	-0.5
High blood pressure (siblings)	0.4	0.6	2.7	0.7	0.9	0.4	1.7	-0.1	1.0	-0.2	0.6	0.1
Leg fat percentage (right)	0.4	1.5	4.3	-0.2	-0.8	-1.4	-0.9	2.0	-0.0	2.1	0.5	1.3
Exposure to tobacco smoke outside home	0.4	0.5	1.5	-0.8	-0.9	-0.3	-0.3	-1.1	-1.2	0.1	0.0	0.9
Health satisfaction	0.4	0.6	3.1	-0.1	-0.3	-0.6	1.1	-0.3	0.0	1.8	0.6	0.3
Heart disease (mother)	0.4	0.5	2.4	-0.1	-0.6	-1.0	-0.2	0.4	0.4	0.3	0.5	1.5
Leg fat mass (right)	0.4	1.5	6.2	0.1	-0.4	-1.2	-1.1	1.7	0.7	2.5	-0.0	1.0
Arm predicted mass (right)	0.4	2.1	5.1	1.3	1.4	1.1	-0.5	-1.4	2.2	1.9	-0.8	-1.5
Overall health rating	0.4	0.9	2.0	-0.6	-1.3	-1.2	0.3	0.5	-0.5	1.4	0.7	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.4	0.2	0.3	0.2	-1.5	-1.3	0.4	1.6	-0.5	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.4	-0.3	-0.5	-0.9	-1.2	-0.7	-0.1	0.9	0.1	-0.2
Number of self-reported non-cancer illnesses	0.4	0.7	3.2	0.1	0.1	0.2	1.8	-0.6	0.6	0.1	1.2	0.8
Miserableness	0.4	0.7	3.2	-0.6	-0.8	-0.5	-0.1	0.2	-1.8	-0.4	-0.9	-0.8
Risk taking	0.4	0.6	1.9	0.8	0.6	-0.0	-0.1	0.2	0.6	1.4	0.8	-1.3
Alzheimer’s Disease (in mother)	0.3	0.4	1.5	0.1	-0.3	-1.2	-0.3	0.5	-0.0	1.2	0.4	0.1
Body Mass Index (BMI) (2010)	0.3	0.4	1.3	0.2	0.2	0.0	-0.2	0.7	0.7	-1.2	-0.4	-0.8
HbA1C	0.3	0.3	1.0	0.5	0.7	0.4	0.2	0.4	1.0	-0.1	0.0	-0.6
BMI	0.3	2.0	9.1	-0.7	-0.5	-0.7	-1.2	3.0	0.4	-1.4	-2.0	0.5
Cardiovascular Disease	0.3	1.1	2.9	-0.6	-0.5	-1.6	-0.5	1.7	0.3	1.1	-0.1	1.5
Ever had hysterectomy (womb removed)	0.3	0.4	1.8	-0.1	-0.3	-0.5	-1.3	0.9	0.2	0.2	0.0	-0.6
Systolic blood pressure, automated reading	0.3	0.8	2.3	0.5	1.0	0.6	0.6	0.7	1.5	-0.9	-0.2	-1.3
Leg fat-free mass (left)	0.3	1.5	3.1	1.0	1.2	1.1	-0.6	-0.8	1.8	1.2	-0.9	-1.7
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.1	-1.1	-0.7	-0.6	-0.1	0.4	-0.4	-0.5	-0.2	0.2
Leg predicted mass (left)	0.3	1.4	2.9	0.9	1.1	1.0	-0.6	-0.8	1.7	1.3	-0.9	-1.6
Allergy	0.3	0.7	1.9	-0.2	-0.5	-1.4	-1.2	-0.4	0.4	1.3	-0.3	0.6
Weight	0.3	1.4	6.9	1.1	0.7	0.2	-0.6	0.1	1.9	2.6	-0.0	-0.4
Forced expiratory volume in 1-second (FEV1)	0.3	0.8	4.3	0.3	0.5	-0.0	-0.1	-0.1	0.8	0.6	-1.3	-2.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.6	-0.2	-0.4	-0.3	0.1	0.0	-0.3	0.9	0.8	1.3
Medication: Lansoprazole	0.3	0.3	0.8	-0.3	-0.5	-0.7	-0.3	0.8	0.0	0.5	-0.3	0.9
Arm fat mass (right)	0.3	1.3	4.7	-0.1	-0.5	-1.0	-1.1	2.2	0.8	1.5	-0.5	1.0
Length of working week for main job	0.3	0.4	1.7	-0.2	-0.3	-0.6	-0.2	0.1	-0.3	0.9	0.2	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.3	0.6	0.1	0.6	-0.3	-1.1	0.4	-0.2	0.9	-0.8
Age at first live birth	0.3	0.5	1.8	0.1	0.6	0.5	-0.4	-1.4	1.3	-0.6	-0.0	-0.3
Pulse rate, automated reading	0.3	1.1	2.4	-0.9	-0.9	-1.2	0.3	1.2	-0.4	1.1	1.2	1.5
Medication: Aspirin	0.3	0.4	1.3	-0.2	-0.7	-0.9	-0.7	0.5	-0.4	0.5	0.6	1.1
Hypertension (Self-reported)	0.3	0.8	2.6	-0.3	0.1	-0.8	0.9	1.0	1.1	0.4	0.4	1.6
Arm fat mass (left)	0.3	1.3	4.6	-0.2	-0.5	-1.1	-1.1	2.1	0.8	1.6	-0.4	1.0
Guilty feelings	0.3	0.5	1.6	-0.6	-0.3	-0.5	-0.7	0.4	-1.1	1.3	-0.1	-0.1
Eye problems/disorders: Glaucoma	0.3	0.4	0.9	0.4	-0.2	-0.8	0.3	-0.2	0.9	0.8	0.7	0.9
Medication: Paracetamol	0.3	0.4	1.8	-0.2	-0.3	-0.3	-0.4	-0.0	-0.2	1.4	0.5	1.0
Medication: Atorvastatin	0.3	0.4	1.2	0.3	0.2	-0.4	0.6	-0.7	-0.1	1.1	0.7	0.6
Fractured/broken bones in last 5 years	0.3	0.3	1.4	-0.3	-0.3	-0.5	-0.4	1.0	-0.0	1.2	-0.1	-0.2
Diastolic blood pressure, automated reading	0.3	1.0	2.8	-0.8	-0.8	-1.4	-0.5	1.5	0.5	-0.6	-1.7	0.3
Vascular/heart problems diagnosed by doctor	0.3	0.8	3.2	0.4	0.3	1.2	-0.6	-0.9	-0.8	-0.7	-0.6	-1.8
Rheumatoid Arthritis	0.2	0.2	0.9	0.2	0.8	1.0	0.4	-0.6	-0.3	-0.2	0.2	0.0
Blood Platelet Count	0.2	2.2	10.4	0.8	0.3	-0.9	-1.5	1.0	1.1	3.2	1.5	0.9
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.3	0.0	-0.1	-0.3	0.3	0.4	-0.1	1.1	1.1	0.2
Relative age of first facial hair	0.2	0.3	2.2	-0.0	0.6	0.1	0.5	1.5	0.1	0.3	0.3	0.4
Angina	0.2	0.3	1.4	0.3	0.3	0.2	-0.3	-1.2	-0.0	0.3	0.1	-0.9
Hand grip strength (right)	0.2	0.5	2.2	-0.2	-0.3	-0.1	-1.5	0.4	-0.3	0.0	-1.1	-1.1
Average weekly fortified wine intake	0.2	0.2	0.5	-0.0	0.3	0.7	0.5	0.3	-0.2	-0.6	-0.6	-0.4
Age when periods started (menarche)	0.2	0.5	1.7	-0.4	-0.5	-0.6	-1.3	-0.1	0.3	-0.6	-0.7	0.9
Body mass index (BMI)	0.2	1.0	6.7	-0.2	-0.2	-0.3	-0.4	2.6	0.3	-0.5	-0.9	0.8
Hearing difficulty/problems with background noise	0.2	0.3	0.9	0.0	-0.2	0.2	1.0	-0.7	0.3	-0.5	0.6	0.7
Worrier / anxious feelings	0.2	0.5	1.9	-0.4	-0.7	-0.4	0.3	-1.4	-1.0	-0.1	-0.4	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.1	-0.1	-0.4	-0.2	0.5	-0.4	-1.1	0.4	0.6	0.1
Depression (self-reported)	0.2	0.3	2.0	0.3	0.0	0.2	0.0	-0.2	-0.4	0.3	0.3	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	3.3	0.7	0.8	0.3	0.5	0.3	0.9	0.3	-0.8	-1.8
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.6	0.1	0.5	0.2	-0.2	1.3	0.2	-0.2	0.2	0.4
Angina (self-reported)	0.2	0.3	1.1	0.4	0.4	0.2	-0.2	-1.1	-0.0	0.0	0.0	-0.9
Medication: Allopurinol	0.2	0.3	1.1	0.2	0.3	0.6	-0.0	-0.2	-0.6	-0.6	0.2	-1.1
Leg fat-free mass (right)	0.2	1.1	2.4	0.7	1.0	1.0	-0.7	-0.6	1.6	0.9	-1.1	-1.3
Long-standing illness, disability or infirmity	0.2	0.3	1.9	-0.3	-0.2	0.0	0.7	-1.4	-0.3	0.1	-0.4	-0.0
Diabetes diagnosed by doctor	0.2	0.3	0.9	-0.4	-0.6	-0.8	0.3	0.1	-0.6	0.9	0.2	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.4	0.4	0.1	0.6	0.0	-1.0	0.1	-1.2	-0.5	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.5	-0.6	-0.6	-0.4	-0.4	0.2	0.2	-1.2	-0.8	-0.6
Leg predicted mass (right)	0.2	1.1	2.6	0.7	1.0	1.0	-0.7	-0.7	1.6	0.9	-1.1	-1.2
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.9	0.0	0.1	0.6	-0.0	-0.8	-0.3	-1.0	-0.7	-0.2
Supplements: Calcium	0.2	0.2	0.6	0.1	0.1	0.2	0.4	-0.4	-0.5	-0.8	-0.5	0.1
Heart disease (siblings)	0.2	0.2	0.7	-0.2	-0.0	-0.2	0.8	-0.6	-0.5	0.6	0.5	-0.4
LDL Cholesterol	0.1	0.2	0.8	-0.3	-0.4	-0.5	-0.2	-0.2	-0.5	-0.4	-0.1	0.9
Systolic Blood Pressure	0.1	0.4	1.2	-0.1	0.8	0.1	0.3	1.1	0.9	-0.6	-0.7	-0.5
Tanning	0.1	0.8	2.9	-0.1	-1.0	-0.9	-1.7	0.9	-0.6	0.7	-0.1	0.9
Hand grip strength (left)	0.1	0.3	1.5	0.4	0.3	0.3	-0.6	0.0	0.1	0.4	-0.4	-1.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.8	0.1	0.0	-0.3	-0.1	-0.9	0.8	0.3	0.2	-0.1
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	0.7	0.2	0.1	0.0	0.3	-0.4	0.4	0.3	0.4	0.8
Medication: Metformin	0.1	0.1	0.4	0.1	-0.0	0.1	0.1	0.4	-0.1	-0.6	0.1	0.3
Had menopause	0.1	0.1	0.3	-0.2	-0.3	-0.5	0.4	0.1	-0.3	0.5	0.2	0.4
Diabetes (self-reported)	0.1	0.2	0.7	-0.3	-0.4	-0.4	0.7	-0.3	-0.4	0.8	0.0	-0.4
Medication: Ramipril	0.1	0.2	0.7	0.4	-0.0	0.0	-0.2	-0.9	0.2	0.3	0.7	0.1
Hip circumference	0.1	0.3	0.9	0.7	0.4	0.4	-0.1	0.2	0.9	0.8	-0.4	-0.2
Exposure to tobacco smoke at home	0.1	0.1	0.4	0.1	0.1	0.5	0.6	0.1	-0.6	-0.2	0.4	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.8	0.0	-0.9	-0.5	-0.1	-0.0	0.0	-0.3	0.4	0.4
Loud music exposure frequency	0.1	0.2	0.5	0.2	0.0	-0.0	0.4	0.7	0.4	0.4	0.1	-0.6
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.3	0.5	0.1	0.5	-0.2	0.1	0.2	0.2	0.1	-0.4
Ever had bowel cancer screening	0.1	0.1	0.5	0.2	0.4	0.3	0.2	-0.1	0.6	-0.1	0.4	0.7
Commuting to job workplace: Walk	0.1	0.1	0.4	0.1	-0.1	0.3	-0.4	0.1	0.4	-0.2	0.0	-0.6
Age started oral contraceptive pill	0.1	0.2	0.4	-0.1	0.3	0.5	0.6	0.4	0.4	-0.6	0.3	-0.0
Unable to work because of sickness or disability	0.1	0.2	0.9	0.1	0.4	0.3	1.0	0.4	-0.1	-0.1	0.3	0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Illnesses of father: Heart disease	0.0	0.0	0.2	-0.1	-0.1	-0.0	0.4	-0.1	0.1	0.1	-0.1	0.0

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