TWAS hub - HOXB9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0646	0.0239	1.3e-05	0.032	0.031	0.048	0.037	0.043	1.2e-05	1.5e-05	9.9e-08	2.3e-06	4.2e-07
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0464	0.0273	7.2e-03	0.001	0.003	0.007	NA	0.001	2.5e-01	1.3e-01	4.4e-02	NA	2.6e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Ovarian Cancer	7.7	10.2	10.5	3.2	-3.1
Ever had bowel cancer screening	7.4	8.6	14.6	-3.8	1.6
Systolic blood pressure, automated reading	6.8	19.6	39.2	0.2	6.3
Mouth/teeth dental problems: Dentures	6.5	10.9	19.9	1.4	-4.5
Systolic Blood Pressure	6.3	31.5	62.3	-0.9	7.9
Exposure to tobacco smoke outside home	6.0	8.1	11.4	2.2	-3.4
Financial situation satisfaction	6.0	7.4	8.9	2.4	-3.0
Health satisfaction	5.8	7.6	11.0	3.3	-2.0
High blood pressure	5.1	14.2	28.3	0.4	5.3
Hand grip strength (left)	4.9	12.9	24.9	5.0	-0.9
Cholesterol lowering medication	4.7	7.0	9.8	2.0	3.1
Overall health rating	4.4	9.4	12.2	3.5	-2.6
Hand grip strength (right)	4.2	11.5	21.3	4.6	-1.3
Exposure to tobacco smoke at home	4.2	4.7	7.3	-1.5	-2.7
Alcohol usually taken with meals	4.1	6.6	10.8	-1.6	3.3
Vascular/heart problems diagnosed by doctor	4.1	11.1	22.1	-0.3	-4.7
Average weekly spirits intake	4.0	5.0	6.2	2.5	-1.9
Peak expiratory flow (PEF)	4.0	9.4	15.1	-3.9	1.9
Hypertension (Self-reported)	4.0	11.1	22.1	0.4	4.7
Cardiovascular Disease	3.9	12.7	22.2	1.8	4.7
Medication for hormone replacement therapy	3.5	3.9	7.1	-2.7	-0.8
Medication: Amlodipine	3.5	4.9	9.8	-0.3	3.1
Medication: Blood pressure	3.5	6.1	11.8	-0.7	3.4
Type 2 Diabetes (T2D) (2012)	3.4	3.9	7.1	-0.9	2.7
Hearing difficulty/problems: Yes	3.4	5.3	5.9	2.4	-2.2
Hair/balding pattern: Pattern 3	3.4	5.0	5.8	2.1	2.4
Angina	3.3	4.4	5.8	-1.7	2.4
Medication: Ventolin 100micrograms inhaler	3.3	4.3	6.7	2.6	-1.3
Schizophrenia vs Biploar Disorder	3.2	4.2	7.5	1.0	-2.7
Waist circumference	3.2	11.6	21.5	4.6	-1.3
Angina (self-reported)	3.2	4.2	4.9	-1.9	2.2
Blood Red Count	3.1	29.6	34.3	5.9	-5.0
Frequency of tiredness / lethargy in last 2 weeks	3.1	5.1	7.3	1.7	-2.7
Diastolic blood pressure, automated reading	3.1	9.6	11.3	3.4	2.8
Basal cell carcinoma (self-reported)	3.1	3.7	4.3	2.1	-1.8
Tinnitus: Yes, now most or all of the time	2.9	3.4	3.7	1.9	-1.8
Alcohol drinker status: Never	2.9	3.5	5.2	1.3	-2.3
Body mass index (BMI)	2.8	12.0	22.5	4.7	-1.2
Rheumatoid Arthritis	2.7	3.7	7.3	-2.7	0.4
Worry too long after embarrassment	2.7	4.6	6.5	2.6	-1.6
Illnesses of siblings: Diabetes	2.7	3.3	4.0	-1.6	2.0
Crohns Disease (2012)	2.6	4.2	4.5	2.0	-2.1
BMI	2.6	15.0	29.4	5.4	-0.7
Sitting height	2.6	18.6	33.4	-5.8	1.9
Mouth/teeth dental problems	2.6	4.1	6.4	-1.3	2.5
Depression (self-reported)	2.6	3.2	3.7	-1.6	1.9
Wheeze or whistling in the chest in last year	2.6	4.7	9.2	3.0	-0.3
Alzheimer’s Disease (in father)	2.5	2.7	4.6	-2.1	-0.8
Blood clot in the leg (DVT)	2.5	3.2	6.3	0.4	-2.5
Deep venous thrombosis (DVT) (self-reported)	2.5	3.2	6.4	-0.2	-2.5
Pain all over the body in last month	2.4	2.5	5.0	0.1	-2.2
Risk taking	2.4	3.5	6.2	-0.9	-2.5
Average weekly fortified wine intake	2.3	2.6	5.3	-0.2	2.3
Lung FEV1/FVC ratio	2.2	11.0	18.1	-4.3	2.0
Lung FVC	2.2	11.4	22.3	4.7	-0.7
Pulse wave Arterial Stiffness index	2.2	2.6	3.6	-1.9	1.2
Pulse wave peak to peak time	2.2	2.6	3.0	1.7	-1.5
Illness, injury, bereavement, stress in last 2 years	2.1	2.6	3.1	-1.8	1.4
Impedance of whole body	2.1	10.7	21.3	-4.6	0.1
Impedance of leg (left)	2.0	9.7	19.1	-4.4	0.5
Family relationship satisfaction	2.0	2.5	3.2	1.4	-1.8
Arm fat percentage (left)	2.0	8.1	13.0	3.6	-1.8
High cholesterol (Self-reported)	2.0	3.5	5.7	2.4	1.2
Medication: Paracetamol	2.0	3.1	4.3	1.3	-2.1
LDL Cholesterol	1.9	3.0	5.8	2.4	-0.4
Ever used hormone-replacement therapy (HRT)	1.9	2.4	4.6	-2.1	0.5
Medication: Atenolol	1.9	2.4	4.2	-0.8	2.0
Arm fat percentage (right)	1.9	7.3	12.1	3.5	-1.6
Medication: Aspirin	1.9	2.6	4.9	-0.5	2.2
Intelligence (Savage-Jansen 2018)	1.8	5.5	5.5	-2.3	2.3
Height	1.8	34.1	67.6	-8.2	0.8
Comparative body size at age 10	1.8	5.1	8.9	3.0	1.1
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.2	3.6	1.9	-0.8
Medication: Blood pressure	1.8	3.5	7.0	0.3	2.6
Verbal and Numeric Reasoning (VNR)	1.7	4.0	5.8	-2.4	1.5
Medication: Omeprazole	1.7	2.1	4.1	-0.1	2.0
Arm fat mass (left)	1.7	6.9	11.3	3.4	-1.6
Fasting Glucose	1.6	1.9	2.6	-1.1	1.6
Ever had hysterectomy (womb removed)	1.6	1.8	3.3	-1.8	-0.4
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	3.7	1.9	-0.7
Medication: Simvastatin	1.6	2.4	3.8	1.0	1.9
Happiness	1.6	1.9	2.3	1.2	-1.5
Arm fat mass (right)	1.6	6.6	11.2	3.3	-1.4
Number of full brothers	1.6	2.0	3.8	-0.4	-1.9
Chest pain or discomfort	1.6	2.2	3.7	0.9	-1.9
Medication: Bendroflumethiazide	1.6	2.4	3.1	-1.3	1.8
Medication: Lisinopril	1.6	2.0	3.8	-0.5	1.9
Body Mass Index (BMI) (2010)	1.5	2.0	3.9	2.0	-0.3
Eye problems/disorders: Diabetes related eye disease	1.5	1.6	2.5	0.9	-1.6
Impedance of arm (right)	1.5	6.9	13.6	-3.7	0.4
Mouth/teeth dental problems: Loose teeth	1.5	1.8	2.0	-1.3	1.4
Medication: Aspirin	1.5	1.9	2.9	-1.0	1.7
Frequency of depressed mood in last 2 weeks	1.4	2.0	2.9	1.0	-1.7
Impedance of leg (right)	1.4	7.0	13.7	-3.7	0.6
Hearing difficulty/problems with background noise	1.4	2.2	2.9	1.7	-1.2
Financial difficulties in last 2 years	1.4	1.8	2.1	1.3	-1.4
Pain experienced in last month	1.4	2.3	4.3	-0.6	2.1
Major Depression (MDD)	1.3	1.6	2.2	-1.0	-1.5
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	3.3	-0.2	-1.8
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	2.6	-1.6	0.7
High blood pressure (mother)	1.3	1.8	3.4	0.4	1.9
Allergy	1.3	3.1	4.0	-2.0	1.5
Hip circumference	1.3	5.6	9.4	3.1	-1.4
Medication: Lansoprazole	1.3	1.5	1.6	-1.2	1.2
Impedance of arm (left)	1.3	6.0	12.0	-3.5	-0.3
Standing height	1.3	13.1	25.5	-5.0	0.8
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	4.1	0.4	-2.0
Leg fat percentage (right)	1.3	4.6	8.7	3.0	-0.7
Back pain experienced in last month	1.3	1.9	3.1	-0.8	-1.8
Wears glasses or contact lenses	1.3	1.5	1.7	-1.1	1.3
Schizophrenia (2014)	1.2	2.7	3.4	1.4	-1.8
Triglycerides	1.2	1.9	2.5	-1.6	1.1
Fed-up feelings	1.2	2.2	4.2	0.5	-2.0
Chronic bronchitis/emphysema (father)	1.2	1.4	1.5	-1.2	-1.2
Medication: Ramipril	1.2	1.5	2.5	-0.7	1.6
Father’s age at death	1.2	1.6	2.8	-1.7	0.7
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	2.3	-1.5	0.7
Leg fat mass (right)	1.2	4.8	9.5	3.1	-0.5
Long-standing illness, disability or infirmity	1.2	1.8	3.1	0.7	-1.8
Average weekly champagne plus white wine intake	1.2	1.7	3.1	-1.8	0.5
Bipolar Disorder or Schizophrenia	1.1	2.6	4.8	2.2	-0.7
Qualifications: CSEs or equivalent	1.1	1.4	2.9	1.7	-0.2
Serious illness, injury or assault to yourself	1.1	1.3	2.2	0.6	-1.5
Hayfever, allergic rhinitis or eczema	1.1	2.4	2.7	1.4	-1.6
Nervous feelings	1.1	2.0	3.4	0.8	1.8
Had other major operations	1.1	1.3	2.6	-0.0	-1.6
Headache pain in last month	1.1	1.9	3.3	0.8	-1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	2.3	1.5	0.5
Age at last live birth	1.1	1.6	2.3	0.9	1.5
Medication: Gliclazide	1.1	1.3	2.6	-1.6	0.0
Number of self-reported non-cancer illnesses	1.1	1.8	2.2	1.2	1.5
Myopia	1.1	1.6	1.7	-1.2	1.3
Bipolar Disorder (2018)	1.0	1.6	3.0	1.7	0.4
Depressed Affect (Nagel 2018)	1.0	2.1	3.6	-0.8	-1.9
Maternal smoking around birth	1.0	1.5	2.2	-1.5	-0.9
Medication: Levothyroxine sodium	1.0	1.8	2.6	1.0	-1.6
Fluid intelligence score	1.0	2.1	3.8	-1.9	0.6
Lung cancer (father)	1.0	1.1	2.0	-1.4	-0.5
Chronic bronchitis/emphysema (mother)	1.0	1.1	2.2	-0.2	-1.5
Medication: Seretide 50 evohaler	1.0	1.1	1.9	-0.6	-1.4
Knee pain experienced in last month	1.0	1.5	1.8	1.1	-1.3
Friendships satisfaction	1.0	1.3	1.8	0.9	-1.3
Number of operations (self-reported)	1.0	1.5	2.8	-1.7	-0.5
Leg fat mass (left)	1.0	4.0	7.7	2.8	-0.5
Schizophrenia (2018)	0.9	1.9	1.9	1.4	-1.4
Blood Platelet Count	0.9	10.5	10.8	-3.3	3.2
Respiratory disease	0.9	2.0	4.0	2.0	0.0
Medication: Metformin	0.9	1.2	2.0	-1.4	0.7
Pack years adult smoking proportion	0.9	1.4	2.8	1.7	0.1
Length of working week for main job	0.9	1.0	1.6	0.7	-1.3
Gout (self-reported)	0.9	1.2	1.3	-1.1	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	2.0	-0.1	-1.4
Number of full sisters	0.9	1.1	2.1	1.4	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	1.8	-0.4	-1.3
Medication for cholesterol	0.9	1.4	2.6	0.4	-1.6
Leg fat percentage (left)	0.9	3.1	5.9	2.4	-0.6
Depression (Nagel 2018)	0.8	1.1	2.2	0.2	-1.5
Alzheimer’s Disease (including proxy)	0.8	1.2	2.1	-0.6	-1.4
Coronary Artery Disease (CAD)	0.8	1.0	1.7	1.3	-0.5
Allergy or Eczema	0.8	2.1	3.3	1.0	-1.8
Supplements: Zinc	0.8	0.9	1.1	0.8	-1.0
Townsend deprivation index at recruitment	0.8	1.2	1.8	0.8	-1.3
Number of incorrect matches in round	0.8	1.4	1.4	-1.1	1.2
Had menopause	0.8	1.0	1.8	-1.4	0.3
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	2.4	-0.4	1.5
Medication: Allopurinol	0.8	1.0	1.3	-0.8	1.2
Guilty feelings	0.8	1.2	2.3	1.5	0.4
Age started oral contraceptive pill	0.8	0.9	1.3	1.1	0.8
Heart attack/myocardial infarction (self-reported)	0.8	1.0	1.5	-0.6	1.2
Primary Biliary Cirrhosis	0.7	1.1	1.7	0.6	-1.3
Diabetes (father)	0.7	0.9	1.3	0.7	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	1.0	1.0	-0.9
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.4	1.2	0.3
Supplements: Glucosamine	0.7	0.9	1.9	-0.2	1.4
Illnesses of siblings	0.7	1.0	1.8	0.4	-1.4
High blood pressure (siblings)	0.7	1.0	1.8	-0.5	1.3
Body fat percentage	0.7	2.7	4.0	2.0	-1.2
Eye problems/disorders: None of the above	0.7	0.8	1.7	-1.3	0.1
Pulse rate, automated reading	0.7	2.2	2.6	1.6	1.4
Suffer from ‘nerves’	0.7	1.1	1.1	-1.1	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.0	0.9	1.0
Mineral and other dietary supplements	0.7	0.9	1.3	-0.7	-1.1
Asthma (self-reported)	0.7	1.3	1.8	1.3	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	2.7	1.6	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	1.7	0.0	1.3
Severe depression (siblings)	0.6	0.7	1.2	-0.3	1.1
Heart attack	0.6	0.7	1.0	-0.7	1.0
Weight	0.6	2.8	5.2	2.3	-0.6
Worrier / anxious feelings	0.6	1.1	1.2	1.0	1.1
Noisy workplace	0.6	0.7	0.8	0.7	-0.9
Asthma	0.6	1.3	1.8	1.4	0.8
Breastfed as a baby	0.6	0.8	1.3	-1.1	0.6
Glaucoma (self-reported)	0.6	0.7	1.0	1.0	-0.7
Age at first live birth	0.6	1.0	2.0	-0.1	1.4
Shortness of breath walking on level ground	0.6	0.8	1.2	0.6	-1.1
Whole body fat mass	0.6	2.3	3.9	2.0	-0.8
Commuting to job workplace: Walk	0.6	0.7	1.3	1.1	0.2
Osteoarthritis (self-reported)	0.6	0.7	1.0	1.0	0.6
Eye problems/disorders: Glaucoma	0.6	0.7	1.0	0.7	-1.0
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.5	0.2	-1.2
Medication: Atorvastatin	0.6	0.8	1.4	1.2	0.4
Ever depressed for a whole week	0.6	0.7	1.4	0.2	-1.2
Supplements: Calcium	0.6	0.6	1.1	-0.4	1.0
Pack years of smoking	0.6	0.8	1.6	1.3	0.1
Age at First Birth	0.5	0.8	1.0	-0.8	1.0
Ulcerative Colitis	0.5	0.7	1.2	0.4	-1.1
Blood White Count	0.5	3.7	5.9	-2.4	1.2
Waist Hip Ratio (WHR)	0.5	2.0	3.8	1.9	-0.6
Leg fat-free mass (left)	0.5	2.4	4.4	2.1	-0.7
Age when periods started (menarche)	0.5	1.2	1.6	-1.3	0.9
Stomach or abdominal pain in last month	0.5	0.6	0.8	-0.6	-0.9
Leg predicted mass (left)	0.5	2.6	4.6	2.1	-0.8
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	0.7	-0.9	-0.7
Diabetes (self-reported)	0.5	0.8	1.5	-1.2	-0.3
Birth weight of first child	0.5	0.8	1.5	1.2	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	0.7	-0.8	-0.8
Qualifications: College or University degree	0.5	1.5	2.2	-1.5	1.0
Migraine (self-reported)	0.5	0.6	1.2	-0.3	-1.1
Medication: Ibuprofen	0.5	0.5	1.0	0.2	-1.0
Alcohol intake frequency.	0.5	1.1	2.1	1.4	-0.4
Comparative height size at age 10	0.5	2.8	5.2	-2.3	0.6
Illnesses of father: Heart disease	0.5	0.7	0.7	0.8	0.8
Breast cancer (self-reported)	0.5	0.6	1.0	-0.4	1.0
Commuting to job workplace: Public transport	0.5	0.6	1.1	0.2	-1.1
Illnesses of father: High blood pressure	0.5	0.6	1.2	-0.1	1.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.1	-1.1	0.2
Fractured/broken bones in last 5 years	0.5	0.7	1.2	-0.4	-1.1
Ulcerative Colitis (UC)	0.4	0.8	1.6	0.3	-1.3
Reaction Time	0.4	0.8	1.5	0.3	-1.2
HbA1C	0.4	0.5	0.9	-0.2	1.0
HDL Cholesterol	0.4	0.7	1.3	0.2	-1.1
Neuroticism (2016)	0.4	0.6	0.7	-0.7	0.8
Hair Pigment	0.4	11.8	19.4	-2.0	-4.4
Trunk fat percentage	0.4	1.7	2.2	1.1	-1.5
Neuroticism score	0.4	0.7	1.4	1.2	-0.3
Number of live births	0.4	0.5	1.1	0.0	-1.0
Pulse rate	0.4	0.7	1.5	0.1	-1.2
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	1.5	0.4	-1.2
Number of children fathered	0.4	0.4	0.5	0.6	-0.7
Had major operations	0.4	0.4	0.5	-0.7	-0.6
Leg pain on walking	0.4	0.4	0.9	0.9	-0.1
Leg fat-free mass (right)	0.4	2.0	3.5	1.9	-0.7
Leg predicted mass (right)	0.4	2.1	3.7	1.9	-0.8
Ever taken oral contraceptive pill	0.4	0.5	0.9	-1.0	0.1
Alzheimer’s Disease (in mother)	0.3	0.4	0.7	-0.3	-0.8
Crohns Disease (2017)	0.3	0.7	1.0	1.0	-0.6
Breast Cancer	0.3	0.8	1.6	-0.3	1.3
Hypothyroidism (self reported)	0.3	0.7	1.4	0.2	-1.2
Chronotype (morning person)	0.3	0.7	0.9	0.7	1.0
Number of treatments/medications taken	0.3	0.5	1.0	0.2	1.0
Relative age of first facial hair	0.3	0.6	1.2	-0.1	-1.1
Medication: Co-codamol	0.3	0.3	0.4	-0.5	-0.6
Trunk fat mass	0.3	1.2	1.4	1.2	-1.0
Qualifications: A levels/AS levels or equivalent	0.3	0.7	1.2	-0.5	1.1
Medication: Cholesterol lowering	0.3	0.4	0.6	0.8	0.5
Prospective memory result	0.3	0.4	0.7	0.3	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.8	-0.9	-0.5
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.6	0.3	-0.8
Emphysema/chronic bronchitis	0.3	0.3	0.6	-0.2	-0.8
Arm predicted mass (right)	0.3	1.4	2.5	1.6	-0.6
Supplements: Vitamin C	0.3	0.4	0.7	0.2	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	1.0	-0.3	-1.0
Mood swings	0.3	0.5	0.7	-0.5	-0.8
Loneliness, isolation	0.3	0.4	0.4	0.6	-0.7
Eye problems/disorders: Cataract	0.3	0.4	0.5	0.7	0.5
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.8	0.9	-0.5
Illnesses of father: None of the above (group 1)	0.3	0.4	0.6	0.3	0.8
Mother’s age at death	0.3	0.3	0.6	-0.8	0.2
Supplements: Fish oil (including cod liver oil)	0.3	0.3	0.5	0.5	0.7
Basal metabolic rate	0.3	1.8	3.4	1.9	-0.5
Average weekly beer plus cider intake	0.3	0.4	0.7	-0.8	-0.3
Worry (Nagel 2018)	0.2	0.5	0.5	0.7	0.7
Irritable Bowel Disease (IBD)	0.2	0.6	0.8	0.6	-0.9
Prostate Cancer	0.2	0.3	0.6	-0.8	0.2
Type 2 Diabetes (T2D) (2018)	0.2	0.5	0.5	-0.7	-0.7
Neuroticism	0.2	0.4	0.8	-0.3	-0.9
Relative age voice broke	0.2	0.4	0.7	0.9	-0.0
Multivitamins +/- minerals	0.2	0.2	0.2	-0.4	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.3	-0.3	-0.6
Illnesses of mother	0.2	0.3	0.5	-0.1	-0.7
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.3	0.6	-0.5
Medication: Paracetamol	0.2	0.3	0.6	-0.1	-0.8
Birth weight	0.2	0.5	0.7	0.8	0.6
Arm fat-free mass (right)	0.2	1.0	2.0	1.4	-0.1
Neck or shoulder pain in last month	0.2	0.3	0.6	0.2	-0.8
Heart disease (mother)	0.2	0.3	0.5	0.7	0.2
Whole body fat-free mass	0.2	1.1	2.1	1.5	-0.2
Average weekly red wine intake	0.2	0.4	0.4	0.6	0.6
Diabetes diagnosed by doctor	0.2	0.4	0.7	-0.8	-0.2
Qualifications: nursing, teaching	0.2	0.3	0.7	-0.8	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.3	-0.3	-0.6
Whole body water mass	0.2	1.3	2.6	1.6	-0.3
Miserableness	0.2	0.4	0.7	0.3	-0.9
Hearing aid user	0.2	0.2	0.3	0.3	-0.5
Arm fat-free mass (left)	0.2	1.1	2.0	1.4	-0.3
Irritability	0.2	0.3	0.4	0.6	-0.4
Arm predicted mass (left)	0.2	0.8	1.5	1.2	-0.3
Neuroticism (Nagel 2018)	0.1	0.2	0.4	0.2	-0.6
Bipolar Disorder (2011)	0.1	0.1	0.2	0.5	0.0
Mean Putamen Volume	0.1	0.1	0.2	0.1	-0.4
Blood Eosinophil Count	0.1	0.8	1.1	-0.7	1.1
Smoking Status	0.1	0.3	0.5	-0.4	-0.7
Vitamin and mineral supplements	0.1	0.1	0.1	0.3	-0.2
Diabetes (mother)	0.1	0.1	0.2	0.1	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.6	0.2	0.8
Past tobacco smoking	0.1	0.2	0.2	0.4	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.2	0.5	-0.3
Forced vital capacity (FVC)	0.1	0.2	0.3	0.6	0.3
Qualifications: None of the above	0.1	0.1	0.2	-0.2	0.5
Trunk fat-free mass	0.1	0.4	0.7	0.8	0.3
Time employed in main current job	0.1	0.1	0.1	-0.2	-0.3
Alcohol intake versus 10 years previously	0.1	0.2	0.4	-0.1	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.3	0.6	-0.1
Trunk predicted mass	0.1	0.4	0.7	0.8	0.3
Tense / ‘highly strung’	0.1	0.2	0.3	0.6	-0.2
Hair/balding pattern: Pattern 4	0.1	0.2	0.3	-0.6	-0.1
Forced vital capacity (FVC), Best measure	0.1	0.5	0.9	1.0	0.0
Smoking status: Previous	0.1	0.2	0.4	-0.0	-0.6
Osteoporosis (self-reported)	0.1	0.1	0.3	-0.5	-0.1
Unable to work because of sickness or disability	0.1	0.1	0.3	-0.5	-0.1
Alcohol drinker status: Previous	0.1	0.1	0.2	-0.2	-0.5
Lupus	0.0	0.0	0.1	-0.2	0.1
Heel T-Score	0.0	0.0	0.1	-0.2	0.2
Tanning	0.0	0.2	0.3	0.6	0.3
Sensitivity / hurt feelings	0.0	0.0	0.0	0.0	0.1
Current tobacco smoking	0.0	0.1	0.1	0.1	-0.3
Taking other prescription medications	0.0	0.0	0.0	-0.1	-0.2
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.0	-0.2	0.2
Hair/balding pattern: Pattern 2	0.0	0.0	0.0	-0.1	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.1	-0.1	0.3
Falls in the last year	0.0	0.0	0.1	-0.1	-0.3
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.1	0.1	0.4
Pulse wave reflection index	0.0	0.1	0.1	-0.1	0.3
Loud music exposure frequency	0.0	0.0	0.0	-0.1	-0.2
Medication for pain relief, constipation, heartburn	0.0	0.0	0.0	-0.0	-0.2
Mean time to correctly identify matches	0.0	0.1	0.2	-0.4	-0.0
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.0	0.0	0.1
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.0	0.2	0.0
Smoking status: Current	0.0	0.0	0.1	0.0	-0.3
Ever smoked	0.0	0.0	0.0	-0.2	0.1
Commuting to job workplace: Cycle	0.0	0.0	0.0	-0.2	0.1
Heart disease (siblings)	0.0	0.1	0.1	-0.3	0.1

Hub : Genes

HOXB9

Models

Trait associations