[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr20:31,382,860-34,737,037

Best TWAS P=2.22e-13 · Best GWAS P=1.21e-12 conditioned to 0.384

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
45	The Cancer Genome Atlas	Stomach Adenocarcinoma	GDF5	0.09	0.04	enet	13	0.05	2.4e-04	7.1	7.3	2.2e-13	0.85	0.00	0.99	TRUE
9	GTEx	Brain Putamen basal ganglia	E2F1	0.18	0.22	lasso	6	0.21	1.2e-05	-6.6	6.5	9.1e-11	0.01	0.03	0.95	TRUE
5	GTEx	Artery Tibial	TP53INP2	0.09	0.08	lasso	1	0.07	5.6e-06	5.7	5.7	1.2e-08	0.06	0.01	0.98	TRUE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	GDF5	0.05	0.05	lasso	5	0.04	7.2e-05	7.1	6.7	1.5e-11	0.95	0.00	1.00	FALSE
6	GTEx	Artery Tibial	GSS	0.06	0.02	enet	25	0.04	7.7e-04	5.7	6.5	7.1e-11	0.35	0.29	0.09	FALSE
27	The Cancer Genome Atlas	Colon Adenocarcinoma	CBFA2T2	0.13	0.04	lasso	1	0.03	1.1e-02	-6.4	6.4	1.6e-10	0.01	0.01	0.68	FALSE
8	GTEx	Brain Hypothalamus	E2F1	0.26	0.02	lasso	5	0.12	9.1e-04	3.2	6.3	2.8e-10	0.06	0.03	0.59	FALSE
7	GTEx	Brain Hippocampus	E2F1	0.39	0.25	lasso	8	0.18	4.1e-05	-6.6	6.2	5.4e-10	-0.01	0.02	0.96	FALSE
17	GTEx	Testis	CBFA2T2	0.10	0.07	enet	11	0.07	6.1e-04	-6.2	6.2	7.1e-10	-0.02	0.08	0.85	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	UQCC1	0.05	0.05	lasso	5	0.06	1.7e-08	5.6	-6.0	1.6e-09	-0.84	0.21	0.79	FALSE
20	NTR	Blood	UQCC	0.01	0.01	enet	6	0.00	1.6e-02	5.5	-6.0	2.0e-09	-0.89	0.08	0.78	FALSE
1	CommonMind	Brain Pre-frontal Cortex	E2F1	0.06	0.01	bslmm	268	0.02	1.6e-03	-6.2	6.0	2.3e-09	0.06	0.04	0.75	FALSE
39	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UQCC	0.07	0.08	blup	67	0.07	1.1e-08	5.4	-5.9	3.9e-09	-0.82	0.05	0.95	FALSE
25	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	UQCC	0.03	0.04	blup	67	0.03	2.6e-03	5.5	-5.9	4.2e-09	-0.91	0.02	0.91	FALSE
40	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	GDF5	0.05	0.02	blup	76	0.04	1.4e-03	5.5	5.9	4.2e-09	0.89	0.03	0.91	FALSE
48	The Cancer Genome Atlas	Thyroid Carcinoma	UQCC	0.15	0.21	blup	67	0.22	1.2e-20	5.7	-5.8	6.4e-09	-0.88	0.49	0.51	FALSE
44	The Cancer Genome Atlas	Soft Tissue Sarcoma	UQCC	0.07	0.06	blup	66	0.07	5.2e-05	5.5	-5.8	8.3e-09	-0.89	0.02	0.97	FALSE
10	GTEx	Breast Mammary Tissue (Male)	UQCC1	0.06	0.04	lasso	1	0.02	1.4e-01	5.7	-5.7	1.2e-08	-0.90	0.04	0.13	FALSE
46	The Cancer Genome Atlas	Thyroid Carcinoma	CEP250	0.05	0.03	blup	43	0.04	5.8e-05	4.5	5.7	1.6e-08	0.78	0.12	0.83	FALSE
34	The Cancer Genome Atlas	Brain Lower Grade Glioma	CBFA2T2	0.02	0.01	blup	31	0.01	1.8e-02	-6.3	5.6	1.8e-08	0.02	0.01	0.70	FALSE
41	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UQCC	0.22	0.21	lasso	7	0.18	1.9e-07	5.3	-5.6	2.0e-08	-0.84	0.31	0.69	FALSE
12	GTEx	Esophagus Mucosa	UQCC1	0.13	0.10	enet	10	0.07	1.1e-05	5.7	-5.6	2.3e-08	-0.89	0.44	0.55	FALSE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	UQCC	0.07	0.10	lasso	8	0.11	1.3e-11	5.4	-5.6	2.3e-08	-0.90	0.36	0.64	FALSE
24	YFS	Blood	UQCC	0.21	0.19	lasso	26	0.20	6.4e-64	5.5	-5.6	2.5e-08	-0.88	0.96	0.04	FALSE
28	The Cancer Genome Atlas	Glioblastoma Multiforme	UQCC	0.15	0.02	blup	67	0.04	2.0e-02	2.2	-5.6	2.5e-08	-0.74	0.02	0.64	FALSE
29	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CEP250	0.02	0.01	blup	43	0.02	8.0e-04	4.6	5.6	2.6e-08	0.79	0.03	0.83	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	UQCC	0.04	0.06	lasso	6	0.05	2.3e-06	5.5	-5.5	3.5e-08	-0.90	0.64	0.36	FALSE
16	GTEx	Stomach	UQCC1	0.09	0.14	lasso	2	0.15	1.9e-07	5.5	-5.5	3.8e-08	-0.86	0.45	0.40	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	GDF5	0.10	0.13	lasso	2	0.12	2.9e-15	5.5	5.5	3.8e-08	0.90	0.80	0.20	FALSE
3	GTEx	Adipose Subcutaneous	UQCC1	0.09	0.12	lasso	2	0.11	4.5e-09	5.5	-5.5	3.9e-08	-0.90	0.92	0.08	FALSE
19	METSIM	Adipose	UQCC1	0.09	0.04	enet	18	0.05	1.5e-07	5.5	-5.5	4.1e-08	-0.90	0.14	0.86	FALSE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CEP250	0.03	0.01	blup	43	0.03	2.6e-04	7.1	5.5	4.6e-08	0.77	0.01	0.89	FALSE
47	The Cancer Genome Atlas	Thyroid Carcinoma	GDF5	0.02	0.00	blup	76	0.00	1.9e-01	5.7	5.4	5.9e-08	0.90	0.02	0.88	FALSE
13	GTEx	Lung	UQCC1	0.13	0.08	lasso	5	0.06	1.0e-05	5.5	-5.4	6.1e-08	-0.90	0.45	0.55	FALSE
31	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UQCC	0.05	0.06	blup	66	0.06	3.6e-07	4.4	-5.4	6.9e-08	-0.87	0.13	0.87	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	GGT7	0.02	0.02	lasso	3	0.02	2.2e-04	5.7	-5.4	7.4e-08	-0.09	0.02	0.88	FALSE
15	GTEx	Skin Sun Exposed Lower leg	UQCC1	0.19	0.13	enet	16	0.10	8.1e-09	5.5	-5.3	8.6e-08	-0.84	0.96	0.04	FALSE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TRPC4AP	0.05	0.03	enet	10	0.04	7.1e-05	-4.0	5.3	1.0e-07	-0.07	0.04	0.81	FALSE
2	CommonMind	Brain Pre-frontal Cortex	UQCC	0.07	0.04	lasso	2	0.05	1.4e-06	5.1	-5.3	1.1e-07	-0.88	0.15	0.85	FALSE
33	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UQCC	0.09	0.10	blup	67	0.10	7.2e-11	5.4	-5.3	1.1e-07	-0.88	0.94	0.06	FALSE
18	GTEx	Thyroid	CBFA2T2	0.11	0.05	enet	18	0.06	2.6e-05	3.3	5.3	1.3e-07	-0.02	0.13	0.84	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	GDF5	0.09	0.11	blup	76	0.12	1.0e-13	5.4	5.3	1.4e-07	0.83	0.14	0.86	FALSE
14	GTEx	Nerve Tibial	UQCC1	0.07	0.04	enet	6	0.03	2.7e-03	5.5	-5.2	1.6e-07	-0.88	0.23	0.74	FALSE
37	The Cancer Genome Atlas	Lung Adenocarcinoma	UQCC	0.10	0.07	enet	10	0.07	1.5e-08	5.6	-5.2	1.6e-07	-0.89	0.09	0.91	FALSE
4	GTEx	Adrenal Gland	MMP24-AS1	0.18	0.04	enet	10	0.13	2.2e-05	4.3	-5.2	1.8e-07	-0.74	0.22	0.21	FALSE
11	GTEx	Cells Transformed fibroblasts	UQCC1	0.23	0.24	lasso	8	0.25	9.4e-19	5.5	-5.2	1.9e-07	-0.88	0.97	0.03	FALSE
38	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MMP24	0.04	0.04	blup	62	0.02	7.4e-04	4.4	-5.2	2.4e-07	-0.55	0.17	0.74	FALSE
23	YFS	Blood	EIF6	0.02	0.00	blup	341	0.01	4.1e-05	4.9	5.1	3.0e-07	0.37	0.88	0.02	FALSE