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chr2:231,628,878-234,434,621

Best TWAS P=1.21e-14 · Best GWAS P=2.11e-11 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellar Hemisphere	PTMA	0.28	0.12	enet	19	0.06	1.5e-02	-5.3	5.1	3.0e-07	-0.48	0.05	0.54	FALSE
2	GTEx	Brain Frontal Cortex BA9	C2orf82	0.24	0.16	lasso	10	0.12	3.9e-04	-4.4	5.2	1.7e-07	0.02	0.04	0.92	FALSE
3	GTEx	Brain Putamen basal ganglia	C2orf82	0.28	0.22	lasso	3	0.18	5.3e-05	-4.5	5.3	1.2e-07	0.01	0.04	0.78	FALSE
4	GTEx	Heart Atrial Appendage	COPS7B	0.22	0.01	lasso	6	0.01	1.3e-01	-5.3	-5.7	9.5e-09	0.66	0.04	0.27	FALSE
5	GTEx	Liver	PDE6D	0.21	0.10	lasso	4	0.09	1.8e-03	-6.7	-7.0	1.8e-12	0.81	0.02	0.89	TRUE
6	GTEx	Thyroid	GIGYF2	0.08	0.02	lasso	3	0.01	6.7e-02	-5.8	-5.1	3.0e-07	-0.02	0.08	0.28	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	NCL	0.16	0.05	lasso	6	0.08	6.1e-10	3.2	5.4	5.2e-08	0.06	0.06	0.94	FALSE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C2orf52	0.15	0.14	enet	8	0.13	3.7e-11	-5.4	5.3	1.1e-07	-0.02	0.02	0.98	FALSE
9	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C2orf52	0.28	0.12	lasso	6	0.12	2.0e-06	-5.7	5.8	8.6e-09	-0.04	0.01	0.99	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	C2orf52	0.21	0.16	blup	42	0.24	7.1e-14	-5.1	5.3	1.5e-07	0.00	0.01	0.99	TRUE
11	The Cancer Genome Atlas	Glioblastoma Multiforme	C2orf52	0.28	0.12	enet	12	0.18	5.0e-06	-5.2	5.4	7.3e-08	-0.03	0.02	0.91	FALSE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C2orf52	0.18	0.20	lasso	3	0.19	3.4e-11	-5.1	5.2	2.4e-07	-0.02	0.02	0.98	FALSE
13	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EFHD1	0.11	0.01	blup	70	0.03	1.0e-02	5.6	7.7	1.2e-14	-0.03	0.01	0.79	TRUE
14	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	KCNJ13	0.07	0.06	enet	13	0.05	4.7e-04	-6.1	5.2	2.5e-07	0.01	0.02	0.90	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	GIGYF2	0.02	0.01	lasso	3	0.01	5.3e-02	-6.1	-6.1	8.5e-10	-0.02	0.03	0.87	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	NGEF	0.03	0.01	blup	130	0.01	2.0e-02	-6.0	5.2	1.6e-07	0.01	0.02	0.89	FALSE
17	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C2orf52	0.13	0.06	lasso	4	0.05	2.1e-03	-5.4	5.3	1.4e-07	-0.03	0.01	0.84	FALSE
18	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C2orf52	0.28	0.18	lasso	4	0.20	3.7e-22	-5.7	5.5	5.1e-08	-0.05	0.00	1.00	FALSE
19	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C2orf52	0.24	0.20	lasso	3	0.20	1.4e-13	-5.1	5.1	2.8e-07	-0.02	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C2orf52	0.32	0.21	lasso	7	0.21	3.6e-09	-5.1	5.1	3.0e-07	-0.06	0.01	0.99	TRUE
21	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	KCNJ13	0.07	0.07	blup	36	0.06	2.4e-03	-6.1	5.7	1.2e-08	0.02	0.01	0.87	FALSE
22	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C2orf52	0.27	0.27	lasso	5	0.28	1.7e-11	-5.4	5.4	7.6e-08	-0.01	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	GIGYF2	0.04	0.00	blup	103	0.02	2.1e-03	-4.5	-5.4	5.3e-08	0.01	0.04	0.80	FALSE
24	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C2orf52	0.21	0.20	lasso	1	0.18	1.4e-05	-5.7	5.7	1.2e-08	-0.02	0.00	0.94	TRUE
25	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C2orf52	0.29	0.17	enet	10	0.19	3.2e-07	-5.4	5.3	1.0e-07	-0.04	0.01	0.98	TRUE
26	The Cancer Genome Atlas	Thyroid Carcinoma	KCNJ13	0.03	0.00	blup	35	0.01	4.3e-02	5.6	-7.0	3.6e-12	-0.02	0.01	0.55	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	NGEF	0.04	0.03	enet	7	0.03	5.6e-04	5.7	-6.6	3.1e-11	0.00	0.03	0.95	FALSE