Hub : Genes

RNF215

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0320 0.0170 1.7e-02 -0.002 0.002 -0.002 0 -0.001 6.7e-01 0.1900 6.8e-01 0.28 4.7e-01
2 GTEx Adrenal Gland 0.2267 0.0802 2.7e-03 0.055 NA 0.059 NA 0.036 5.0e-03 NA 3.6e-03 NA 2.0e-02
3 GTEx Heart Atrial Appendage 0.4560 0.0600 2.2e-16 0.463 NA 0.417 NA 0.432 4.8e-23 NA 3.3e-20 NA 4.2e-21
4 GTEx Heart Left Ventricle 0.2128 0.0474 5.7e-09 0.260 NA 0.241 NA 0.237 3.9e-14 NA 4.3e-13 NA 7.1e-13
5 GTEx Lung 0.1171 0.0424 8.6e-04 0.058 NA 0.031 NA 0.042 3.3e-05 NA 1.9e-03 NA 3.8e-04
6 GTEx Muscle Skeletal 0.0851 0.0358 3.4e-03 -0.002 NA 0.009 NA 0.005 6.5e-01 NA 4.1e-02 NA 1.0e-01
7 GTEx Nerve Tibial 0.0767 0.0315 2.1e-03 0.065 NA 0.043 NA 0.055 2.1e-05 NA 5.2e-04 NA 9.3e-05
8 TCGA Pancreatic Adenocarcinoma 0.1580 0.0820 2.7e-03 0.084 0.040 0.043 NA 0.095 2.2e-04 0.0087 6.5e-03 NA 8.6e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.7 1.0 2.8 -1.0 -1.1 -1.1 -1.1 0.2 -1.7 1.1 -0.1
Bipolar Disorder or Schizophrenia 2.7 6.7 13.1 1.3 -1.5 -3.6 -3.5 0.7 -3.3 3.4 -0.8
Depressed Affect (Nagel 2018) 0.3 0.6 1.2 -0.8 -0.7 0.8 0.9 0.7 0.6 -1.1 0.2
Depression (Nagel 2018) 0.5 0.8 4.9 -0.5 -2.2 -0.2 -0.2 -0.1 0.9 0.0 -0.3
Intelligence (Savage-Jansen 2018) 0.6 1.9 6.0 -2.4 -1.5 1.2 1.2 -0.5 1.3 -1.2 -0.7
Neuroticism (Nagel 2018) 0.2 0.4 1.0 -0.9 -0.5 0.4 0.5 -0.2 1.0 -0.6 0.1
Schizophrenia (2018) 3.2 6.7 14.5 2.5 -0.8 -3.8 -3.7 0.8 -2.0 3.6 -0.8
Schizophrenia vs Biploar Disorder 0.4 0.5 1.7 1.3 0.1 -1.0 -0.9 -0.1 -0.2 0.9 -0.2
Worry (Nagel 2018) 0.1 0.2 1.4 -1.2 -0.2 -0.3 -0.2 0.1 0.1 -0.0 0.3
Alzheimer’s Disease (in mother) 0.5 0.5 0.9 -0.4 0.9 0.7 0.9 -0.6 -0.5 -0.9 -0.9
Alzheimer’s Disease (in father) 0.9 1.0 3.7 1.4 0.7 0.1 0.2 1.9 0.1 -0.4 1.1
Alzheimer’s Disease (including proxy) 0.3 0.4 1.1 -0.4 0.7 0.6 0.8 0.0 -0.5 -1.1 -0.8
Crohns Disease (2017) 0.2 0.4 1.7 0.1 1.3 -0.1 -0.1 -1.1 -0.1 0.2 -0.6
Irritable Bowel Disease (IBD) 0.2 0.5 1.1 1.0 1.1 -0.7 -0.7 -0.6 -0.2 0.5 0.1
Ulcerative Colitis (UC) 0.3 0.6 1.4 0.9 0.5 -1.2 -1.1 -0.0 -0.7 0.9 0.3
Major Depression (MDD) 0.9 1.1 5.9 -0.3 -2.4 -0.1 -0.1 -1.0 0.5 -0.1 -1.2
Reaction Time 0.1 0.2 0.5 0.1 0.4 -0.4 -0.4 -0.4 0.0 0.4 0.7
Verbal and Numeric Reasoning (VNR) 0.9 2.2 6.9 -2.6 -2.5 0.9 0.8 -0.6 0.8 -0.7 -1.3
Breast Cancer 0.6 1.5 2.4 0.9 1.3 1.3 1.3 -0.8 1.5 -1.1 1.5
Ovarian Cancer 0.1 0.2 0.6 -0.6 0.1 -0.0 -0.0 -0.8 -0.2 0.1 -0.6
Prostate Cancer 1.4 1.9 4.0 1.2 0.4 -2.0 -1.8 0.2 -1.3 1.7 -1.4
Age at First Birth 0.6 0.8 3.0 -0.0 1.7 -0.5 -0.7 0.8 -1.3 0.8 -0.0
Bipolar Disorder (2011) 0.4 0.4 0.8 -0.8 -0.5 0.5 0.6 0.3 0.5 -0.6 0.9
Body Mass Index (BMI) (2010) 0.5 0.6 2.8 1.7 0.2 0.2 0.3 0.5 0.4 -0.3 1.2
Coronary Artery Disease (CAD) 3.5 4.2 9.0 -1.8 -2.1 2.8 2.8 0.1 0.9 -3.0 0.3
Crohns Disease (2012) 0.4 0.6 0.9 0.9 1.0 -0.7 -0.7 -0.3 -0.6 0.8 -1.0
Mean Putamen Volume 0.6 0.7 3.9 1.0 2.0 0.0 0.0 -0.2 -0.5 0.1 0.4
Fasting Glucose 0.6 0.7 3.5 1.9 0.4 -0.1 -0.2 0.7 0.1 0.2 1.2
HbA1C 0.6 0.6 2.6 -0.1 0.1 -0.6 -0.7 -1.6 -0.4 0.9 0.8
HDL Cholesterol 1.4 2.3 8.7 1.1 -0.2 -1.1 -1.2 2.0 -2.9 1.2 -0.5
LDL Cholesterol 0.8 1.3 2.4 -1.2 -1.2 -0.9 -0.9 -1.2 -0.9 0.9 -1.6
Lupus 0.3 0.5 1.5 0.7 0.6 -0.5 -0.4 0.6 0.7 0.3 1.2
Neuroticism (2016) 0.2 0.2 1.5 0.2 -1.2 -0.1 0.0 -0.3 -0.3 -0.2 -0.2
Primary Biliary Cirrhosis 3.3 4.6 8.8 -2.7 -0.8 3.0 2.9 -0.4 1.8 -3.0 0.6
Rheumatoid Arthritis 1.2 1.6 5.1 1.4 2.3 0.7 0.8 1.1 0.3 -0.8 1.6
Schizophrenia (2014) 1.9 4.1 8.7 1.9 -1.2 -2.9 -2.8 0.2 -2.1 2.5 -0.8
Triglycerides 0.6 1.0 2.8 0.3 -1.7 -1.1 -1.0 -0.9 0.9 1.0 0.2
Type 2 Diabetes (T2D) (2012) 0.9 1.1 3.6 0.7 -1.0 -0.7 -0.7 1.9 -0.3 0.8 1.3
Ulcerative Colitis 1.4 2.1 5.3 2.3 1.7 -1.2 -1.2 1.4 -1.2 1.2 0.8
Blood Eosinophil Count 2.1 16.0 39.4 6.3 4.9 -3.6 -3.5 3.1 -3.9 3.7 0.7
Blood Platelet Count 4.9 56.7 102.0 8.9 2.9 -9.9 -10.0 5.1 -6.2 10.1 1.5
Blood Red Count 0.8 7.8 30.8 -0.5 -2.3 -0.5 -0.4 -4.9 -1.2 0.4 -5.5
Blood White Count 0.3 2.4 6.7 2.6 -1.9 -1.4 -1.5 -0.9 -0.3 1.7 -1.0
Heel T-Score 3.1 24.6 47.7 3.4 4.4 -5.7 -5.8 2.3 -6.9 6.3 -2.4
BMI 0.4 2.5 10.9 3.3 1.8 -0.7 -0.7 1.6 -0.4 0.8 1.2
Height 0.0 0.8 1.8 0.5 0.9 1.0 0.9 1.3 0.2 -1.0 0.6
Waist Hip Ratio (WHR) 5.9 26.4 45.6 -6.8 -2.5 6.3 6.4 -2.6 5.0 -6.8 1.2
Systolic Blood Pressure 0.4 1.8 9.3 0.1 0.8 0.5 0.4 3.1 -1.5 -0.7 1.0
Smoking Status 0.6 1.3 2.9 0.4 0.0 -1.0 -1.1 1.7 -1.5 1.3 1.1
Allergy or Eczema 0.7 1.7 2.9 1.4 1.7 -1.7 -1.5 -0.2 -1.4 1.3 -0.3
Cardiovascular Disease 0.9 2.8 4.5 -0.9 -0.5 2.0 2.0 1.7 1.5 -2.0 2.1
Hypothyroidism (self reported) 1.9 4.3 6.8 -1.6 1.6 2.6 2.6 1.1 1.5 -2.5 2.5
Respiratory disease 0.7 1.7 3.4 1.1 -0.8 -1.8 -1.8 -0.4 -1.5 1.5 -0.5
Type 2 Diabetes (T2D) (2018) 0.7 1.4 7.3 2.7 0.3 -0.0 0.0 1.5 -0.4 -0.2 0.9
Lung FEV1/FVC ratio 0.6 2.8 15.8 -4.0 1.5 0.2 0.4 -1.0 1.1 -0.5 -1.3
Lung FVC 2.1 10.6 16.7 2.9 4.0 -4.0 -4.1 2.1 -2.1 4.1 1.6
Neuroticism 0.1 0.2 1.0 -1.0 0.3 0.2 0.3 0.5 0.2 -0.4 0.1
Chronotype (morning person) 0.9 2.2 12.4 -0.9 -3.5 -0.6 -0.5 -1.0 -0.1 0.3 -1.6
Hair Pigment 0.1 1.7 9.0 0.7 3.0 -0.6 -0.7 1.1 -0.5 0.8 0.9
Tanning 0.3 4.0 7.4 1.1 2.3 -2.7 -2.5 0.9 -2.0 2.4 -0.6
Hand grip strength (left) 0.5 1.4 3.9 2.0 1.6 -0.3 -0.3 -0.3 -1.1 0.4 -1.8
Number of treatments/medications taken 0.7 1.3 2.7 -0.4 -1.6 0.9 0.9 0.4 1.6 -1.2 1.2
Average weekly spirits intake 0.4 0.5 1.8 -0.5 1.3 -0.6 -0.7 -0.2 0.3 0.7 0.5
Sensitivity / hurt feelings 0.6 1.0 3.4 -0.8 -0.6 0.7 0.7 -1.8 1.2 -0.7 -0.8
Frequency of depressed mood in last 2 weeks 0.9 1.2 6.0 -0.9 -2.4 -0.2 -0.2 -0.9 1.2 0.1 -0.9
Hearing difficulty/problems: Yes 0.8 1.2 2.0 1.0 -0.8 -1.4 -1.4 0.1 -0.8 1.3 -1.2
Relative age of first facial hair 1.6 3.4 8.6 1.3 2.9 1.9 1.7 0.6 1.2 -1.4 2.6
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 3.3 0.1 -1.7 0.6 0.5 1.4 0.9 -0.5 1.8
Ever used hormone-replacement therapy (HRT) 1.2 1.6 5.7 0.1 -1.6 0.5 0.4 2.4 -1.1 -0.5 1.6
Ever had hysterectomy (womb removed) 0.2 0.2 0.9 0.6 -0.9 0.1 0.1 0.3 -0.4 -0.4 0.3
Systolic blood pressure, automated reading 1.4 4.0 14.4 2.3 1.4 -0.9 -0.9 3.8 -2.1 0.6 1.9
Eye problems/disorders: Diabetes related eye disease 0.7 0.7 1.8 1.3 -0.7 -0.5 -0.5 1.3 -1.0 0.4 0.6
Angina 1.8 2.4 5.2 -0.8 -1.1 2.3 2.3 -0.3 1.4 -2.3 0.1
Medication for hormone replacement therapy 2.2 2.5 9.7 0.0 0.5 -1.1 -1.1 -1.4 -2.1 1.1 -3.1
Vitamin and mineral supplements 0.8 1.1 3.6 -1.6 -1.9 0.4 0.4 -0.4 -0.4 -0.6 -1.3
Supplements: Zinc 1.2 1.3 3.4 -0.2 0.3 -0.9 -0.8 -1.6 -1.4 0.8 -1.8
Medication: Co-codamol 1.3 1.5 7.2 0.9 0.0 0.9 0.8 1.1 0.9 -0.9 2.7
Medication: Metformin 1.4 2.0 5.8 2.0 -0.8 0.1 0.1 2.1 1.0 -0.4 2.4
Diabetes (father) 0.6 0.7 1.2 0.8 -0.9 -1.0 -1.0 0.5 -1.1 0.9 -0.4
Diabetes (mother) 1.3 1.6 5.2 2.0 0.8 -0.7 -0.7 2.3 -0.2 0.4 1.3
Severe depression (siblings) 1.6 1.8 6.4 0.7 -1.8 -0.1 -0.2 1.9 0.7 0.4 2.5
Pack years adult smoking proportion 0.8 1.3 8.1 0.3 -2.9 0.3 0.4 0.1 1.0 -0.7 0.2
Impedance of leg (right) 0.9 4.5 17.2 -4.1 -2.5 1.6 1.8 -1.3 -0.3 -1.9 -1.2
Leg fat-free mass (left) 0.3 1.4 4.5 2.1 1.4 0.9 0.7 0.3 1.6 -0.7 0.7
Trunk fat percentage 0.8 3.0 6.2 -0.2 0.1 2.5 2.3 1.2 1.2 -2.2 2.1
Hand grip strength (right) 1.3 3.5 8.4 2.9 1.0 -1.9 -1.9 0.7 -1.9 2.1 -1.7
Townsend deprivation index at recruitment 0.4 0.6 1.4 -0.6 -1.1 1.2 1.0 -0.1 0.1 -0.8 0.0
Current tobacco smoking 0.4 0.7 4.6 0.7 -2.1 -0.1 -0.2 -0.0 -0.1 0.4 -0.3
Average weekly fortified wine intake 1.3 1.5 2.6 -1.5 -0.6 1.6 1.6 -1.0 0.1 -1.5 -1.1
Maternal smoking around birth 0.7 1.1 2.1 0.9 0.3 -1.4 -1.5 1.0 -0.7 1.4 0.3
Fed-up feelings 1.2 2.1 5.2 -2.1 -2.3 0.6 0.7 -1.3 1.3 -0.8 -1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.6 3.8 -0.4 -1.9 -0.3 -0.3 -0.3 0.1 0.4 -0.8
Relative age voice broke 1.3 2.0 6.0 0.8 2.1 0.9 0.9 0.4 1.5 -0.8 2.5
Taking other prescription medications 0.4 0.6 2.1 -0.0 -1.3 0.0 0.1 0.7 0.8 -0.4 1.4
Age when periods started (menarche) 2.8 6.7 12.2 2.6 2.2 -3.3 -3.3 1.0 -2.6 3.5 -0.3
Bilateral oophorectomy (both ovaries removed) 0.5 0.5 1.2 -1.1 -0.9 0.8 0.8 -0.3 0.2 -0.9 -0.2
Heel bone mineral density (BMD) T-score, automated (left) 1.1 2.5 5.8 0.7 2.1 -1.4 -1.4 -0.2 -2.4 1.6 -1.6
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.6 -0.2 -0.8 -0.4 -0.4 0.4 -0.7 0.0 -0.4
Qualifications: CSEs or equivalent 0.9 1.2 2.4 -0.7 -0.1 1.3 1.3 -1.4 1.5 -1.2 -0.1
Serious illness, injury or assault to yourself 0.3 0.4 2.1 -1.5 -0.8 0.0 0.0 0.4 0.2 -0.1 -0.3
High blood pressure 1.3 3.6 6.5 -0.5 -0.2 2.2 2.2 2.1 1.7 -2.2 2.5
Hayfever, allergic rhinitis or eczema 0.1 0.3 1.1 0.7 1.0 -0.3 -0.1 -0.5 -0.4 -0.0 0.1
Multivitamins +/- minerals 0.6 0.8 1.9 0.7 1.3 0.4 0.4 -0.6 1.4 -0.3 1.1
Stomach or abdominal pain in last month 1.1 1.3 5.6 0.1 -2.4 -0.2 -0.2 1.6 0.5 0.1 1.5
Supplements: Glucosamine 0.2 0.3 0.7 -0.1 -0.4 0.9 0.8 -0.2 0.3 -0.6 -0.3
Diverticular disease/diverticulitis (self-reported) 0.4 0.4 1.3 -0.4 0.3 0.8 0.8 1.2 -0.1 -0.7 0.3
Medication: Atenolol 1.1 1.4 3.0 -0.9 -0.9 1.7 1.7 0.5 0.3 -1.5 0.8
Medication: Levothyroxine sodium 1.8 3.0 5.7 -1.9 0.8 2.0 2.2 0.4 1.5 -2.4 1.6
Sitting height 0.2 1.6 6.0 2.5 0.3 -1.3 -1.4 0.9 -0.0 1.6 -0.3
Chronic bronchitis/emphysema (father) 0.4 0.5 2.0 0.4 -0.7 0.4 0.5 0.6 -1.4 -0.7 0.5
High blood pressure (mother) 1.2 1.6 2.4 -1.4 -1.0 1.4 1.4 -0.9 1.2 -1.6 -1.1
Body mass index (BMI) 0.3 1.4 4.9 2.2 1.2 0.5 0.4 0.8 1.0 -0.3 1.5
Impedance of leg (left) 0.5 2.6 8.5 -2.9 -1.8 1.4 1.5 -1.0 -0.7 -1.6 -0.8
Leg predicted mass (left) 0.3 1.5 4.6 2.1 1.4 0.9 0.8 0.3 1.6 -0.7 0.8
Trunk fat mass 0.6 2.6 4.4 0.9 0.7 2.1 1.9 1.2 1.4 -1.9 2.0
Waist circumference 1.2 4.2 8.7 -0.2 0.4 2.8 2.8 -0.1 2.5 -3.0 1.7
Number of incorrect matches in round 0.5 0.9 2.5 1.2 -1.6 -0.7 -0.7 0.6 -1.0 0.7 0.8
Past tobacco smoking 2.7 4.9 12.8 -0.8 -1.0 2.2 2.2 -3.6 1.8 -2.0 -2.7
Alcohol usually taken with meals 0.4 0.7 2.5 -0.4 1.6 -0.4 -0.3 0.1 -1.2 0.3 -1.0
Nervous feelings 0.3 0.6 3.0 -1.7 -0.5 0.5 0.5 -0.8 0.5 -0.3 -0.1
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.7 2.0 0.3 -1.2 0.1 0.1 -1.4 0.5 -0.0 -1.4
Hearing difficulty/problems with background noise 0.3 0.5 1.2 0.3 -1.1 -0.9 -0.8 0.9 -0.4 0.6 0.5
Hair/balding pattern: Pattern 2 0.4 0.6 1.3 -0.9 -1.2 0.5 0.5 0.6 0.6 -0.6 0.8
Had menopause 1.7 2.1 5.3 2.2 0.4 -0.8 -0.9 2.3 -1.4 0.8 1.6
Had other major operations 0.1 0.2 0.5 0.4 0.5 -0.2 -0.2 0.4 -0.7 0.3 -0.3
Forced vital capacity (FVC) 0.4 1.7 5.8 1.6 2.4 -1.2 -1.3 0.5 -0.2 1.4 0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 4.4 0.1 2.1 -0.4 -0.4 -0.0 -1.5 0.7 -0.9
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.3 0.2 1.1 -0.7 -0.7 -0.1 -0.3 0.8 -1.1
Qualifications: None of the above 0.2 0.4 2.2 -0.6 -1.5 -0.1 -0.0 -0.1 -0.0 -0.4 0.3
Financial difficulties in last 2 years 0.2 0.3 1.1 0.9 0.7 0.1 0.1 1.1 -0.2 0.1 -0.1
Mouth/teeth dental problems 0.6 0.9 1.6 1.2 1.3 -0.7 -0.8 0.2 -1.0 0.9 -1.2
Heart attack 2.1 2.7 5.4 -1.2 -0.9 2.1 2.0 -0.7 2.3 -2.1 0.7
Allergy 0.1 0.3 1.3 -1.1 -0.4 0.2 0.0 0.4 0.8 0.3 -0.0
Pain all over the body in last month 0.6 0.6 4.7 -0.2 -2.2 -0.2 -0.2 0.2 -0.5 0.0 -0.0
Diabetes (self-reported) 1.7 2.7 7.4 2.7 0.6 -0.4 -0.4 2.5 0.1 0.2 2.6
Hayfever/allergic rhinitis (self-reported) 0.8 1.1 3.1 -1.2 0.5 1.0 1.1 -1.8 0.6 -1.1 -0.5
Medication: Ramipril 0.4 0.5 1.6 0.2 -0.9 -0.8 -0.8 -0.4 1.3 0.7 0.3
Medication: Simvastatin 0.5 0.8 2.8 -0.1 -0.4 0.9 1.0 0.0 1.7 -1.2 0.5
Fluid intelligence score 1.0 2.1 5.5 -2.3 -2.3 0.4 0.4 -1.2 1.0 -0.3 -1.7
Illnesses of siblings 0.7 1.0 4.4 0.5 2.1 0.2 0.2 -1.4 -0.2 0.2 -1.2
Neuroticism score 0.2 0.4 1.4 -1.2 -0.6 0.0 0.1 -0.5 0.0 -0.0 -1.2
Weight 0.4 2.2 5.6 2.4 1.3 1.3 1.2 0.8 1.5 -1.1 1.6
Impedance of arm (right) 1.3 6.1 23.4 -4.8 -2.9 2.3 2.3 -0.8 0.1 -2.3 -0.8
Arm fat percentage (right) 0.5 1.9 4.0 -0.1 -0.4 2.0 1.8 0.6 1.4 -1.7 1.5
Trunk fat-free mass 0.3 1.8 8.8 3.0 2.1 0.3 0.3 -0.1 1.0 -0.3 0.1
Hip circumference 0.4 1.5 2.4 1.4 0.8 1.4 1.3 0.4 1.5 -1.3 1.3
Time employed in main current job 2.0 2.3 5.6 2.0 0.6 -1.3 -1.4 2.4 -0.5 1.6 1.6
Alcohol intake versus 10 years previously 0.2 0.3 1.2 0.4 0.3 0.5 0.4 1.1 -0.4 -0.4 0.4
Father’s age at death 1.6 2.2 5.4 0.3 1.7 -1.1 -1.2 2.3 -2.0 1.5 0.3
Worrier / anxious feelings 0.1 0.3 1.0 -1.0 -0.4 0.2 0.2 -0.2 0.6 -0.3 0.7
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 1.8 -1.1 -1.4 0.8 0.7 -0.4 0.4 -0.7 0.0
Falls in the last year 1.2 1.6 3.3 -1.5 0.5 1.8 1.7 -0.5 0.8 -1.6 0.4
Hair/balding pattern: Pattern 3 1.0 1.4 2.6 0.3 1.1 1.6 1.5 0.4 1.3 -1.4 1.3
Number of live births 3.5 5.0 11.5 -2.8 0.4 2.1 2.3 -1.6 3.4 -2.5 1.1
Forced expiratory volume in 1-second (FEV1) 0.5 1.7 5.4 -0.1 2.3 -1.6 -1.6 -0.1 0.3 1.8 -0.3
Pulse rate 0.2 0.3 0.8 0.4 0.5 -0.5 -0.5 -0.9 0.4 0.3 -0.8
Happiness 1.0 1.2 3.1 -0.7 -1.6 0.7 0.8 -1.0 1.8 -0.9 0.5
Noisy workplace 0.7 0.9 2.2 0.4 0.6 1.0 1.1 0.7 0.9 -1.1 1.5
Qualifications: A levels/AS levels or equivalent 1.8 4.0 6.7 -1.0 1.9 2.6 2.5 0.4 1.8 -2.4 2.3
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 1.4 -0.8 -0.5 0.3 0.3 0.4 1.2 -0.2 1.0
Mouth/teeth dental problems: Dentures 0.5 0.9 2.4 -1.6 -0.7 -0.0 -0.1 1.4 -0.1 -0.0 1.4
Asthma 0.2 0.4 1.6 0.7 0.2 -0.5 -0.4 -1.3 -0.7 0.2 -0.2
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.3 1.4 -0.3 -1.2 0.0 -0.2 0.5 -0.3 0.4 -0.4
Medication: Cholesterol lowering 0.5 0.7 1.7 0.4 -1.1 0.3 0.3 0.8 1.3 -0.5 1.3
Depression (self-reported) 1.9 2.3 5.6 -2.4 -1.4 1.4 1.4 -1.3 1.0 -1.4 -1.5
Medication: Lansoprazole 2.0 2.3 4.8 -0.2 -0.8 1.9 1.9 -0.3 1.9 -2.2 1.3
Prospective memory result 0.3 0.4 1.1 1.0 0.4 -0.5 -0.4 0.2 -0.9 0.3 -0.5
Lung cancer (father) 1.2 1.4 3.3 0.4 1.6 -0.1 -0.2 1.8 -1.5 0.2 1.7
Illnesses of mother 0.6 0.7 1.9 0.6 -0.0 -1.2 -1.2 -0.4 -0.8 1.4 -0.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.6 4.2 -0.6 2.1 -1.2 -1.2 -1.4 0.4 1.4 -1.3
Pulse wave Arterial Stiffness index 0.3 0.3 0.6 0.7 0.2 0.4 0.4 0.5 -0.6 -0.8 0.7
Impedance of arm (left) 1.6 7.3 27.0 -5.2 -3.2 2.5 2.5 -1.0 0.2 -2.5 -0.9
Arm fat mass (right) 0.4 1.5 2.4 1.1 0.2 1.6 1.4 0.4 1.6 -1.4 1.3
Trunk predicted mass 0.3 1.8 9.1 3.0 2.0 0.2 0.2 -0.0 1.0 -0.3 0.1
Standing height 0.2 1.5 3.2 0.6 0.5 1.8 1.7 0.1 1.4 -1.7 0.4
Length of working week for main job 0.5 0.5 1.4 -0.0 0.9 0.5 0.5 0.0 1.0 -0.6 1.2
Exposure to tobacco smoke at home 1.2 1.3 6.5 -0.2 0.6 -0.1 -0.2 1.7 0.8 0.1 2.5
Breastfed as a baby 0.3 0.3 0.8 0.6 -0.6 0.5 0.3 0.7 0.6 -0.2 0.9
Tense / ‘highly strung’ 0.5 0.9 2.8 -0.3 -0.9 -1.0 -0.9 -1.0 -0.6 0.7 -1.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.1 0.2 0.5 -0.4 -0.1 -0.4 -0.4 0.3 -0.1 0.4 -0.7
Hair/balding pattern: Pattern 4 0.3 0.8 1.4 1.0 -0.3 1.1 1.1 -0.0 0.9 -1.2 0.8
Birth weight of first child 0.0 0.1 0.2 0.4 -0.2 0.2 0.0 -0.3 0.4 0.2 -0.1
Peak expiratory flow (PEF) 0.6 1.3 3.6 0.1 1.9 -1.4 -1.4 -0.4 0.6 1.6 -0.1
Pulse wave reflection index 0.1 0.2 0.3 -0.6 0.5 0.5 0.4 -0.1 -0.2 -0.4 0.5
Ever highly irritable/argumentative for 2 days 0.3 0.3 0.8 -0.9 -0.2 0.5 0.6 0.3 0.5 -0.6 0.5
Loud music exposure frequency 0.1 0.1 0.4 -0.3 0.0 0.0 0.1 -0.3 0.5 0.0 -0.6
Qualifications: O levels/GCSEs or equivalent 0.9 1.5 3.2 0.0 1.4 1.8 1.7 0.7 0.6 -1.5 1.0
Mouth/teeth dental problems: Bleeding gums 0.9 1.2 2.7 -0.5 -0.5 1.4 1.3 0.4 0.8 -1.2 1.6
Blood clot in the leg (DVT) 0.7 0.9 5.8 -0.6 -2.4 0.2 0.2 0.6 -0.0 -0.1 -0.6
Medication: Paracetamol 1.7 2.9 11.7 -2.3 -3.4 1.0 0.9 -1.0 1.3 -1.0 -0.8
Headache pain in last month 1.7 2.9 9.3 -2.4 -3.1 0.7 0.8 -1.7 0.9 -1.0 -1.5
Medication for cholesterol, blood pressure or diabetes 0.9 1.5 4.4 -0.2 0.7 -1.0 -0.9 -1.4 -1.6 0.9 -2.1
Glaucoma (self-reported) 0.6 0.7 2.6 -0.2 -1.6 0.8 0.7 0.4 0.7 -0.7 0.9
Gout (self-reported) 1.0 1.3 5.0 0.6 0.7 -0.4 -0.5 2.2 -0.3 0.7 1.9
Hypothyroidism/myxoedema (self-reported) 1.1 2.2 3.9 -1.2 0.8 1.7 1.8 0.8 1.2 -2.0 1.9
Medication: Amlodipine 0.6 0.8 1.8 -0.6 0.7 1.3 1.3 -0.3 0.2 -1.3 0.7
Medication: Ventolin 100micrograms inhaler 1.1 1.4 5.6 2.4 1.5 -0.3 -0.1 -1.3 -0.8 -0.2 -0.6
Birth weight 0.7 1.5 4.1 2.0 2.0 -0.0 -0.1 1.0 0.5 0.2 1.6
Chronic bronchitis/emphysema (mother) 1.8 2.1 6.7 1.9 0.3 -0.9 -0.9 2.1 0.2 0.8 2.6
High blood pressure (siblings) 0.8 1.1 2.9 -1.2 -1.7 1.0 1.0 -0.4 0.8 -1.2 0.4
Forced vital capacity (FVC), Best measure 0.4 1.5 3.0 1.3 1.7 -1.3 -1.4 -0.5 -0.4 1.7 -0.6
Body fat percentage 0.6 2.5 5.1 0.1 0.1 2.3 2.1 1.0 1.1 -2.1 2.0
Leg fat percentage (right) 0.3 1.0 2.0 0.6 0.4 1.3 1.3 0.8 0.5 -1.3 1.4
Arm fat-free mass (right) 0.4 2.2 7.7 2.8 2.1 0.9 0.9 -0.2 1.5 -0.9 0.7
Exposure to tobacco smoke outside home 0.1 0.2 0.6 0.8 -0.2 0.1 -0.1 0.0 -0.7 0.3 -0.4
Comparative body size at age 10 0.6 1.7 3.4 1.5 -0.6 1.5 1.4 -0.9 1.8 -1.5 0.9
Number of full brothers 0.5 0.6 1.1 -0.9 -0.2 -0.9 -0.9 -0.5 0.3 0.9 -1.1
Worry too long after embarrassment 0.4 0.7 2.5 1.6 1.6 0.0 -0.0 -0.1 0.8 0.3 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 3.4 1.8 0.5 0.1 0.1 1.0 0.2 -0.1 0.6
Wheeze or whistling in the chest in last year 0.5 0.9 2.5 -0.8 -1.6 0.2 0.4 -1.2 0.0 -0.6 -1.3
Number of children fathered 0.3 0.4 1.2 -0.0 -0.8 0.1 0.1 -1.1 0.9 0.2 0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 2.9 -1.0 -1.7 0.5 0.4 -0.1 0.4 -0.4 1.0
Age at first live birth 0.3 0.5 2.0 -0.3 0.8 0.5 0.4 1.4 0.0 -0.3 0.9
Pulse wave peak to peak time 0.3 0.3 0.6 -0.6 -0.2 -0.5 -0.5 -0.5 0.5 0.8 -0.7
Health satisfaction 1.3 1.7 5.1 1.0 -0.7 0.9 1.0 0.5 1.9 -1.1 2.2
Shortness of breath walking on level ground 1.0 1.1 3.5 1.3 1.9 -0.7 -0.7 1.0 -0.4 0.6 1.2
Qualifications: College or University degree 0.4 1.1 3.4 1.8 0.4 -1.2 -1.1 0.7 0.7 1.2 0.6
Eye problems/disorders: None of the above 1.5 1.7 4.8 0.2 2.2 -0.9 -1.0 0.2 -1.7 1.1 -1.7
Mouth/teeth dental problems: Loose teeth 2.3 2.7 6.0 0.0 -0.7 -2.5 -2.3 1.2 -1.8 2.1 0.7
Emphysema/chronic bronchitis 1.3 1.5 3.1 0.0 -0.8 1.6 1.6 1.4 0.2 -1.8 1.0
Medication for pain relief, constipation, heartburn 1.5 2.6 8.9 0.3 3.0 -1.4 -1.4 -0.7 -1.9 1.4 -1.2
Neck or shoulder pain in last month 0.4 0.6 1.3 -0.5 -0.1 -1.1 -1.1 0.6 -0.7 0.9 -0.3
Medication: Blood pressure 2.4 4.2 6.9 -0.6 -0.4 2.6 2.4 1.1 2.6 -2.4 2.6
Angina (self-reported) 2.4 3.2 6.6 -1.0 -1.4 2.6 2.5 -0.4 1.7 -2.5 0.2
Migraine (self-reported) 2.4 2.9 9.8 -3.1 -1.5 1.2 1.3 -1.6 1.5 -1.4 -1.1
Medication: Ibuprofen 0.3 0.4 1.9 -0.3 -1.4 0.6 0.4 0.6 -0.2 -0.0 -0.3
Medication: Allopurinol 1.2 1.5 4.1 1.2 0.1 -1.0 -1.1 2.0 -1.1 1.3 1.2
Medication: Omeprazole 0.2 0.3 0.9 1.0 0.2 0.3 0.4 0.2 0.3 -0.7 0.6
Medication: Seretide 50 evohaler 0.2 0.2 0.4 -0.1 -0.4 -0.6 -0.5 -0.6 -0.5 0.5 -0.4
Mean time to correctly identify matches 0.1 0.2 1.1 -0.4 -0.0 0.2 0.2 0.2 0.1 -0.3 1.1
Heart disease (mother) 1.9 2.3 4.4 0.0 0.7 2.1 2.1 -0.1 2.0 -2.1 0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 2.9 -1.7 -1.3 -1.2 -1.1 -0.1 -0.2 0.9 -0.8
Whole body fat mass 0.5 2.0 3.4 1.1 0.4 1.8 1.7 0.9 1.3 -1.7 1.7
Leg fat mass (right) 0.3 1.3 2.2 1.5 0.9 1.3 1.2 0.6 1.0 -1.2 1.2
Arm predicted mass (right) 0.4 2.1 9.4 3.1 2.0 0.5 0.5 0.2 1.4 -0.6 0.8
Pulse rate, automated reading 1.0 3.4 8.0 0.3 -0.3 -2.0 -1.9 -2.0 -1.9 1.8 -2.8
Alcohol intake frequency. 0.4 0.9 2.1 -0.2 -0.3 0.9 1.1 -1.5 0.9 -1.3 -0.1
Comparative height size at age 10 0.1 0.7 1.9 1.4 0.9 -0.1 -0.0 -1.0 -0.2 -0.2 -1.2
Number of full sisters 0.5 0.7 3.0 -1.7 0.9 -0.2 -0.1 -0.6 0.9 -0.1 0.5
Suffer from ‘nerves’ 0.3 0.5 2.2 -1.5 -0.7 -0.2 -0.2 -0.4 -0.4 0.2 -0.9
Overall health rating 0.3 0.7 3.7 0.5 -1.9 -0.3 -0.2 -0.3 1.0 0.1 0.4
Chest pain or discomfort 0.8 1.1 2.6 -0.6 -1.2 1.0 1.1 -0.4 1.6 -1.2 0.7
Had major operations 1.2 1.4 2.1 -1.1 -0.7 1.4 1.4 0.8 1.2 -1.4 1.4
Age at last live birth 0.5 0.7 1.6 -0.3 1.3 -0.8 -0.8 0.4 -0.8 1.2 -0.6
Family relationship satisfaction 1.9 2.4 6.6 -2.0 -2.6 1.1 1.2 -1.0 1.8 -1.1 -0.5
Leg pain on walking 0.7 0.9 2.0 1.1 1.1 -0.3 -0.4 1.2 0.8 0.7 1.4
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.4 2.3 0.8 0.7 1.5 1.4 0.0 1.4 -1.3 1.4
Commuting to job workplace: Car/motor vehicle 1.4 1.6 2.6 -1.3 -0.7 1.6 1.6 -1.1 1.4 -1.4 0.4
Illness, injury, bereavement, stress in last 2 years 0.6 0.7 2.8 -0.2 -0.5 0.6 0.6 0.1 1.2 -0.7 1.7
Medication: Aspirin 1.2 1.6 4.3 -0.2 -0.4 1.0 1.0 1.3 1.8 -1.2 2.1
Supplements: Vitamin C 1.0 1.2 3.8 2.0 0.5 -1.1 -1.1 0.5 -1.1 1.2 0.3
Knee pain experienced in last month 1.9 2.9 6.8 1.1 0.5 -2.3 -2.1 1.1 -2.6 1.8 -0.8
Hypertension (Self-reported) 1.3 3.7 7.8 -0.9 -0.2 2.2 2.2 2.0 1.6 -2.2 2.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.3 0.3 0.2 -0.1 0.1 0.5 -0.3 -0.4 0.5
Illnesses of father: Heart disease 1.6 2.1 5.9 -2.2 -2.4 1.0 0.8 -1.3 1.6 -0.5 -0.6
Illnesses of siblings: Diabetes 1.6 1.9 4.9 0.9 -0.1 -2.2 -2.2 0.8 -0.5 2.0 -0.1
Smoking status: Previous 3.3 4.9 10.2 0.5 1.9 -2.4 -2.3 3.2 -2.2 2.1 2.2
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.2 3.3 -0.6 1.0 1.1 1.1 -1.3 1.8 -0.9 -0.3
Whole body fat-free mass 0.3 1.9 8.7 3.0 1.9 0.5 0.4 0.2 1.3 -0.4 0.6
Leg fat-free mass (right) 0.3 1.8 8.2 2.9 1.8 0.5 0.4 0.5 1.3 -0.3 0.8
Arm fat percentage (left) 0.5 1.9 4.3 -0.1 -0.2 2.1 1.9 0.4 1.5 -1.8 1.4
Average weekly red wine intake 1.3 1.9 9.1 0.7 3.0 -0.4 -0.3 1.8 0.2 0.1 1.4
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.6 -0.8 -0.5 0.6 0.6 0.3 -0.1 -0.5 -0.1
Mood swings 1.2 2.2 4.7 -2.2 -1.9 1.6 1.6 -0.2 1.1 -1.6 0.1
Loneliness, isolation 1.4 2.0 3.1 -1.8 -1.1 1.7 1.7 -0.2 1.5 -1.7 -0.7
Long-standing illness, disability or infirmity 0.4 0.6 2.3 1.5 -0.5 -0.2 -0.3 1.2 -0.4 0.4 0.4
Ever had bowel cancer screening 0.6 0.7 1.1 0.5 -0.9 1.1 0.9 0.7 0.5 -0.9 1.1
Diabetes diagnosed by doctor 1.5 2.5 7.0 2.5 0.5 0.0 0.1 2.4 1.0 -0.2 2.6
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.7 -1.3 -0.5 -0.2 -0.1 0.5 -0.1 -0.1 -0.6
Friendships satisfaction 2.3 2.9 4.9 -1.6 -2.0 1.7 1.8 -1.5 2.2 -1.8 0.1
Qualifications: nursing, teaching 0.2 0.3 1.1 0.1 1.1 -0.0 0.1 -0.0 1.1 -0.1 -0.4
Commuting to job workplace: Walk 0.5 0.6 3.6 1.9 -0.3 -0.1 -0.1 0.3 -0.5 -0.0 -0.6
Eye problems/disorders: Cataract 2.4 2.8 6.4 -1.0 -1.2 1.8 1.9 -1.2 2.5 -1.9 1.2
Mouth/teeth dental problems: Mouth ulcers 1.1 1.7 5.3 -0.8 -0.3 1.0 1.2 -2.3 1.6 -1.4 -0.9
Medication for cholesterol 0.2 0.3 1.3 -0.1 -1.1 -0.0 0.0 -0.3 0.8 -0.2 0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 1.3 -0.4 -1.1 0.9 0.9 -0.0 0.2 -1.0 0.4
Back pain experienced in last month 0.6 0.9 2.8 0.1 -1.7 -1.0 -1.1 -0.5 -0.1 1.3 -0.4
Mineral and other dietary supplements 0.4 0.6 1.9 0.1 0.6 -0.7 -0.8 0.8 -1.4 0.8 -0.3
Breast cancer (self-reported) 0.6 0.7 3.8 -0.4 -0.1 -0.5 -0.5 -1.0 -0.3 0.5 -2.0
Asthma (self-reported) 0.2 0.3 1.3 0.6 0.2 -0.6 -0.4 -1.1 -0.6 0.2 -0.0
Osteoporosis (self-reported) 0.3 0.3 1.1 0.3 -1.0 0.4 0.2 0.3 0.9 -0.2 0.6
Osteoarthritis (self-reported) 1.0 1.3 2.6 1.1 -1.2 1.2 1.1 0.6 1.0 -0.9 1.6
Medication: Aspirin 1.7 2.3 5.1 -0.3 0.0 1.4 1.4 1.8 1.9 -1.5 2.3
Medication: Gliclazide 0.9 1.0 1.5 0.5 -1.1 0.9 0.9 1.2 1.1 -0.9 1.2
Illnesses of father: None of the above (group 1) 0.6 0.8 5.7 0.5 2.4 -0.1 -0.1 0.1 0.2 0.2 0.3
Smoking status: Current 0.4 0.6 4.0 0.5 -2.0 0.5 0.3 -0.1 0.4 -0.1 -0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 1.8 3.5 -1.0 1.4 -1.8 -1.8 -0.9 0.9 1.9 -0.1
Whole body water mass 0.3 1.9 8.9 3.0 2.0 0.5 0.4 0.1 1.3 -0.4 0.5
Leg predicted mass (right) 0.4 1.9 8.5 2.9 1.9 0.5 0.4 0.5 1.3 -0.3 0.8
Arm fat mass (left) 0.5 1.9 3.3 1.0 0.4 1.8 1.7 0.2 1.7 -1.7 1.4
Number of self-reported non-cancer illnesses 1.5 2.6 6.9 -0.3 -1.1 1.6 1.5 2.2 0.8 -1.7 2.6
Average weekly champagne plus white wine intake 0.7 0.9 2.3 0.1 0.6 1.2 1.2 -0.7 1.5 -1.2 0.1
Miserableness 0.2 0.4 0.7 -0.7 -0.9 -0.7 -0.6 0.8 0.0 0.6 0.1
Guilty feelings 0.7 1.0 3.5 0.6 -1.1 -0.7 -0.7 -1.1 -0.8 0.7 -1.9
Wears glasses or contact lenses 0.5 0.6 2.9 1.7 1.3 -0.0 -0.0 0.4 0.3 0.1 0.5
Ever taken oral contraceptive pill 0.5 0.5 2.2 -0.5 -0.6 -0.1 -0.1 -1.5 1.0 0.2 -0.7
Hearing aid user 1.4 1.6 3.3 -1.8 -1.8 -1.0 -0.9 -0.9 -0.3 0.6 -1.8
Mother’s age at death 1.1 1.4 5.4 1.0 0.0 -0.8 -0.7 2.3 -1.4 0.6 1.3
Financial situation satisfaction 0.7 0.9 3.1 1.0 0.4 0.5 0.5 1.0 1.1 -0.4 1.8
Tinnitus: Yes, now most or all of the time 3.4 4.0 6.2 2.3 2.4 -2.1 -2.0 2.5 -1.6 2.0 0.3
Commuting to job workplace: Public transport 2.1 2.5 10.7 0.3 -0.6 -1.0 -1.1 3.3 -1.1 0.9 2.1
Eye problems/disorders: Glaucoma 0.2 0.2 0.7 -0.2 -0.9 0.4 0.3 -0.1 0.5 -0.3 0.5
Medication: Blood pressure 0.3 0.5 1.5 -0.4 1.2 0.3 0.3 1.2 -0.7 -0.4 0.6
Pain type(s) experienced in last month: Hip pain 1.7 2.1 4.0 -1.0 -1.2 2.0 1.9 -1.3 1.2 -1.6 -1.1
Supplements: Fish oil (including cod liver oil) 0.9 1.2 2.4 -0.1 0.4 1.2 1.3 -1.6 1.3 -1.5 -0.2
High cholesterol (Self-reported) 0.3 0.5 1.2 -0.3 -1.1 0.5 0.5 0.9 0.7 -0.7 0.2
Medication: Bendroflumethiazide 0.5 0.8 1.6 0.0 0.1 1.1 1.2 1.1 0.4 -1.3 0.9
Medication: Paracetamol 2.3 3.6 15.2 -2.1 -3.9 1.3 1.2 -1.3 1.8 -1.1 -0.4
Medication: Lisinopril 1.6 2.1 5.0 -0.8 -0.3 1.6 1.5 1.4 1.4 -1.5 2.2
Medication: Atorvastatin 0.2 0.3 0.7 0.7 -0.8 -0.3 -0.3 0.0 -0.6 0.3 -0.6
Illnesses of father: High blood pressure 0.7 0.9 2.7 -1.7 -1.1 -0.7 -0.8 0.7 -0.5 1.0 -0.3
Alcohol drinker status: Never 0.7 0.8 2.4 1.5 0.5 -1.1 -1.1 -0.1 -0.4 1.2 0.2
Ever smoked 1.7 3.0 5.2 0.4 0.1 -2.1 -2.1 2.3 -2.2 2.0 1.1
Basal metabolic rate 0.4 2.0 7.9 2.8 1.9 0.8 0.8 0.2 1.4 -0.7 0.7
Leg fat percentage (left) 0.4 1.6 3.5 1.4 0.9 1.4 1.3 0.9 0.6 -1.3 1.9
Arm fat-free mass (left) 0.4 2.2 10.4 3.2 2.4 0.4 0.4 0.1 1.0 -0.5 0.6
Number of operations (self-reported) 0.7 1.0 2.1 -0.3 0.0 1.1 1.2 -0.3 1.4 -1.2 1.2
Average weekly beer plus cider intake 1.3 1.8 4.6 0.8 -0.7 -2.0 -2.1 -0.3 -0.5 2.0 -0.6
Irritability 0.4 0.7 2.1 -1.5 -0.8 0.5 0.5 -0.9 -0.1 -0.4 -1.1
Risk taking 0.3 0.4 1.3 -1.1 -0.4 0.3 0.3 0.5 -0.3 -0.3 -1.0
Ever had prostate specific antigen (PSA) test 1.3 1.5 6.1 1.9 2.5 -0.8 -0.7 -0.3 -0.2 0.8 -0.6
Fractured/broken bones in last 5 years 2.6 3.3 8.8 -1.6 -0.1 2.6 2.7 -0.2 0.9 -3.0 0.3
Age started oral contraceptive pill 0.2 0.3 1.4 0.3 0.7 0.3 0.3 0.1 -0.1 -0.6 1.2
Diastolic blood pressure, automated reading 0.5 1.5 3.6 -0.9 -0.0 1.8 1.8 0.5 0.5 -1.9 0.9
Ever depressed for a whole week 0.6 0.8 3.1 -0.7 0.9 0.4 0.4 -1.1 0.3 -0.3 -1.8
Unable to work because of sickness or disability 0.7 0.9 2.6 1.4 -0.1 0.6 0.4 0.2 1.6 -0.2 1.4
Commuting to job workplace: Cycle 0.0 0.1 0.2 0.0 0.0 -0.1 -0.1 0.3 0.5 -0.0 0.3
Myopia 0.3 0.5 1.4 0.5 1.2 -0.6 -0.7 -0.4 0.3 0.7 -0.8
Vascular/heart problems diagnosed by doctor 1.7 4.6 7.6 1.0 0.7 -2.8 -2.7 -1.7 -2.1 2.7 -2.5
Cholesterol lowering medication 0.3 0.4 0.8 0.9 0.1 0.8 0.8 0.3 0.8 -0.8 0.5
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 2.6 1.6 0.5 -0.6 -0.5 0.7 0.2 0.1 1.3
Pain experienced in last month 0.2 0.3 1.4 -0.2 1.2 0.2 0.2 -0.2 0.0 -0.3 -0.6
Supplements: Calcium 0.1 0.2 0.3 -0.6 -0.4 -0.6 -0.5 0.1 -0.4 0.0 -0.1
Basal cell carcinoma (self-reported) 1.2 1.5 4.8 1.2 -0.4 -0.3 -0.5 1.5 1.6 0.5 2.2
Heart attack/myocardial infarction (self-reported) 2.0 2.6 5.7 -0.9 -0.6 2.1 2.0 -0.4 2.4 -2.0 1.1
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 5.0 -0.5 -2.2 0.2 0.1 0.7 -0.2 -0.1 -0.7
Heart disease (siblings) 1.3 1.6 4.6 -0.3 -1.6 0.8 0.8 0.8 1.6 -0.9 2.1
Alcohol drinker status: Previous 0.9 1.0 2.4 1.3 0.2 -1.3 -1.1 0.2 -1.6 0.9 -0.2
Pack years of smoking 0.8 1.2 7.8 0.6 -2.8 0.2 0.3 0.5 0.8 -0.6 0.2
Impedance of whole body 1.4 6.9 24.9 -5.0 -3.1 2.5 2.5 -1.1 0.1 -2.6 -0.7
Leg fat mass (left) 0.5 1.9 4.1 2.0 1.1 1.5 1.3 0.6 1.2 -1.3 1.6
Arm predicted mass (left) 0.4 2.0 10.4 3.2 1.8 0.3 0.3 0.2 1.1 -0.4 0.7