[Hub]/) : Traits : Arm predicted mass (right) :

chr1:31,402,148-34,592,020

Best TWAS P=8.82e-24 · Best GWAS P=1.01e-24 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PEF1 0.04 0.04 lasso 4 0.03 2.8e-04 -6.7 6.7 2.9e-11 -0.01 0.09 0.90 FALSE
2 CommonMind Brain Pre-frontal Cortex PHC2 0.12 0.09 bslmm 500 0.12 4.7e-14 3.9 5.5 3.3e-08 -0.58 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex S100PBP 0.05 0.04 enet 10 0.02 1.2e-03 -6.5 5.5 3.7e-08 -0.02 0.97 0.00 FALSE
4 CommonMind Brain Pre-frontal Cortex TMEM54 0.05 0.00 blup 281 0.02 4.5e-03 2.8 -9.8 1.3e-22 0.50 0.12 0.21 FALSE
5 CommonMind Brain Pre-frontal Cortex TXLNA 0.04 0.04 bslmm 221 0.03 1.8e-04 6.0 -5.4 5.7e-08 -0.01 0.59 0.30 FALSE
6 CommonMind Brain Pre-frontal Cortex ZNF362 0.05 0.06 lasso 1 0.06 2.2e-07 -10.1 -10.1 8.8e-24 0.98 0.01 0.99 TRUE
7 GTEx Artery Aorta PEF1 0.15 0.05 lasso 5 0.04 2.2e-03 -7.1 8.0 1.7e-15 -0.05 0.02 0.96 TRUE
8 GTEx Artery Tibial PEF1 0.10 0.09 enet 16 0.09 9.0e-08 -6.7 5.7 1.0e-08 -0.04 0.10 0.90 FALSE
9 GTEx Brain Cerebellum RP11-415J8.3 0.25 0.06 lasso 3 0.07 4.2e-03 5.1 -5.1 3.1e-07 0.53 0.14 0.06 FALSE
10 GTEx Cells EBV-transformed lymphocytes KPNA6 0.19 0.14 enet 18 0.10 4.9e-04 6.0 6.7 2.0e-11 -0.03 0.21 0.09 FALSE
11 GTEx Cells EBV-transformed lymphocytes PHC2 0.58 0.34 lasso 7 0.28 7.3e-10 -10.1 9.8 7.2e-23 -0.99 0.01 0.99 FALSE
12 GTEx Cells Transformed fibroblasts KPNA6 0.13 0.10 lasso 5 0.11 1.3e-08 6.1 6.0 1.5e-09 -0.03 0.90 0.10 FALSE
13 GTEx Colon Sigmoid PEF1 0.16 0.09 lasso 3 0.09 4.3e-04 -7.0 7.4 1.6e-13 -0.04 0.03 0.87 FALSE
14 GTEx Heart Atrial Appendage RN7SKP16 0.08 0.06 enet 11 0.03 1.9e-02 4.1 -6.0 2.5e-09 0.56 0.15 0.46 FALSE
15 GTEx Muscle Skeletal ZNF362 0.04 0.01 enet 7 0.02 4.9e-03 4.1 -6.4 1.7e-10 0.68 0.07 0.80 FALSE
16 GTEx Muscle Skeletal FNDC5 0.15 0.16 enet 5 0.16 1.9e-15 -6.0 -6.0 1.8e-09 0.06 1.00 0.00 FALSE
17 GTEx Skin Not Sun Exposed Suprapubic EIF3I 0.12 0.06 lasso 1 0.03 7.2e-03 6.0 -6.0 2.2e-09 0.03 0.08 0.06 FALSE
18 GTEx Skin Sun Exposed Lower leg PEF1 0.05 0.03 enet 9 0.02 4.6e-03 -7.1 6.1 1.0e-09 -0.06 0.02 0.97 FALSE
19 GTEx Testis RP4-622L5.7 0.12 0.11 lasso 5 0.08 2.3e-04 6.0 6.0 2.2e-09 -0.03 0.32 0.21 FALSE
20 GTEx Thyroid TMEM54 0.10 0.09 lasso 7 0.07 3.3e-06 -5.2 5.1 2.7e-07 -0.05 0.99 0.00 FALSE
21 METSIM Adipose KPNA6 0.07 0.06 lasso 10 0.06 1.8e-09 6.0 6.2 4.0e-10 -0.03 0.91 0.09 FALSE
22 METSIM Adipose PEF1 0.03 0.02 enet 17 0.02 7.9e-04 -6.7 6.7 2.0e-11 -0.02 0.04 0.90 FALSE
23 METSIM Adipose ZNF362 0.09 0.02 enet 32 0.03 1.5e-05 -10.1 -7.0 2.4e-12 0.70 0.01 0.98 FALSE
24 ROSMAP Brain Pre-frontal Cortex KPNA6 0.03 0.04 lasso 4 0.02 8.1e-04 6.1 6.2 7.9e-10 -0.02 0.67 0.13 FALSE
25 ROSMAP Brain Pre-frontal Cortex PHC2 0.11 0.07 lasso 3 0.05 2.2e-07 -10.1 -9.7 5.0e-22 0.99 0.01 0.99 FALSE
26 ROSMAP Brain Pre-frontal Cortex PEF1 0.04 0.04 lasso 3 0.02 4.2e-04 -6.7 6.6 3.9e-11 -0.01 0.09 0.89 FALSE
27 YFS Blood KPNA6 0.03 0.03 bslmm 236 0.04 1.1e-11 6.1 6.5 6.6e-11 0.01 0.90 0.10 FALSE
28 The Cancer Genome Atlas Breast Invasive Carcinoma FNDC5 0.02 0.01 blup 33 0.01 9.2e-03 -4.8 -5.2 2.4e-07 0.06 0.02 0.43 FALSE
29 The Cancer Genome Atlas Breast Invasive Carcinoma S100PBP 0.03 0.02 blup 46 0.02 6.6e-06 -6.5 6.3 2.6e-10 -0.07 0.01 0.99 FALSE
30 The Cancer Genome Atlas Breast Invasive Carcinoma ZNF362 0.03 0.01 blup 49 0.01 1.3e-03 4.0 -7.5 6.3e-14 0.72 0.01 0.32 FALSE
31 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma S100PBP 0.06 0.03 blup 48 0.06 6.8e-04 -5.9 7.0 1.8e-12 -0.06 0.01 0.82 TRUE
32 The Cancer Genome Atlas Glioblastoma Multiforme S100PBP 0.21 0.15 lasso 5 0.15 2.9e-05 -6.0 6.0 2.5e-09 -0.06 0.01 0.91 FALSE
33 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma S100PBP 0.04 0.04 lasso 4 0.04 2.3e-05 -6.5 6.5 7.9e-11 -0.08 0.00 0.99 FALSE
34 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM39B 0.04 0.03 blup 16 0.03 5.0e-04 6.0 -5.1 3.0e-07 0.01 0.01 0.94 FALSE
35 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FNDC5 0.03 0.04 enet 6 0.03 2.9e-04 -5.9 -5.6 2.1e-08 0.08 0.04 0.89 FALSE
36 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HPCA 0.05 0.09 lasso 7 0.08 3.6e-09 -4.8 5.3 1.0e-07 -0.06 0.20 0.80 FALSE
37 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MTMR9L 0.03 0.03 blup 28 0.01 1.6e-02 3.1 5.2 2.2e-07 -0.02 0.03 0.58 FALSE
38 The Cancer Genome Atlas Brain Lower Grade Glioma KPNA6 0.02 0.02 blup 29 0.02 1.9e-03 6.0 6.0 2.5e-09 -0.02 0.02 0.87 FALSE
39 The Cancer Genome Atlas Brain Lower Grade Glioma S100PBP 0.06 0.06 blup 47 0.05 5.2e-06 -6.5 6.5 1.1e-10 -0.07 0.00 1.00 FALSE
40 The Cancer Genome Atlas Skin Cutaneous Melanoma MTMR9L 0.15 0.02 blup 29 0.09 2.8e-03 3.5 5.6 2.5e-08 0.01 0.01 0.38 FALSE
41 The Cancer Genome Atlas Testicular Germ Cell Tumors PTP4A2 0.09 -0.01 blup 26 0.00 4.1e-01 6.8 7.9 3.5e-15 0.00 0.01 0.61 TRUE
42 The Cancer Genome Atlas Thyroid Carcinoma KPNA6 0.03 0.03 blup 28 0.03 5.3e-04 6.1 5.8 7.4e-09 -0.02 0.02 0.89 FALSE
43 The Cancer Genome Atlas Thyroid Carcinoma MTMR9L 0.03 0.04 blup 28 0.03 3.3e-04 2.9 5.1 3.0e-07 -0.03 0.03 0.93 FALSE