[Hub]/) : Traits : Arm fat-free mass (left) : ←

chr22:38,787,166-43,226,599

Best TWAS P=3.64e-11 · Best GWAS P=5.86e-15 conditioned to 6.48e-06

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
28	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ADSL	0.09	0.03	lasso	3	0.01	7.7e-02	-6.7	-6.6	3.6e-11	0.11	0.00	0.76	TRUE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	WBP2NL	0.06	0.04	blup	140	0.03	9.6e-05	-5.3	5.8	5.0e-09	-0.53	0.58	0.24	TRUE
10	GTEx	Heart Atrial Appendage	MGAT3	0.14	0.14	lasso	2	0.12	3.5e-06	-5.7	5.7	1.5e-08	-0.07	0.01	0.99	TRUE
13	GTEx	Pituitary	APOBEC3G	0.34	0.04	enet	11	0.11	1.2e-03	4.9	5.6	1.8e-08	0.03	0.13	0.22	TRUE
27	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ADSL	0.06	0.02	lasso	2	0.03	6.6e-03	-6.5	-6.5	9.3e-11	0.05	0.00	0.80	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	TNRC6B	0.02	0.01	blup	92	0.01	2.7e-03	-5.6	-6.1	9.9e-10	0.12	0.02	0.79	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	ADSL	0.03	0.00	blup	33	0.01	8.9e-03	-6.4	-5.9	3.7e-09	0.06	0.01	0.60	FALSE
11	GTEx	Lung	RP5-821D11.7	0.08	0.02	enet	21	0.04	6.6e-04	3.6	5.8	6.7e-09	-0.40	0.53	0.04	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WBP2NL	0.10	0.04	blup	140	0.05	1.8e-06	-3.7	5.7	1.3e-08	-0.40	0.98	0.00	FALSE
2	GTEx	Adipose Subcutaneous	CYP2D6	0.26	0.10	enet	34	0.20	1.2e-16	-3.7	-5.7	1.4e-08	0.45	1.00	0.00	FALSE
14	GTEx	Skin Sun Exposed Lower leg	MGAT3	0.13	0.05	lasso	3	0.02	4.7e-03	-5.7	5.7	1.6e-08	-0.08	0.01	0.98	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADSL	0.04	0.03	enet	6	0.03	1.6e-04	-6.7	-5.5	3.0e-08	0.02	0.00	0.94	FALSE
12	GTEx	Nerve Tibial	SYNGR1	0.26	0.18	enet	27	0.21	3.6e-15	-4.8	-5.5	5.1e-08	0.05	0.08	0.92	FALSE
16	GTEx	Spleen	CCDC134	0.23	0.00	enet	14	0.09	2.7e-03	-5.3	5.4	6.3e-08	-0.40	0.07	0.07	FALSE
3	GTEx	Adipose Subcutaneous	MGAT3	0.08	0.04	lasso	4	0.04	4.3e-04	-5.5	5.4	7.7e-08	-0.07	0.02	0.98	FALSE
7	GTEx	Breast Mammary Tissue (Female)	POLR3H	0.09	-0.01	lasso	6	-0.01	6.4e-01	-5.3	5.4	8.5e-08	-0.46	0.04	0.06	FALSE
18	GTEx	Vagina	APOBEC3G	0.23	0.07	lasso	5	0.06	1.8e-02	4.7	5.3	1.1e-07	0.05	0.10	0.12	FALSE
25	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ADSL	0.07	0.02	blup	33	0.05	5.2e-04	-3.2	-5.3	1.1e-07	0.10	0.07	0.49	FALSE
5	GTEx	Brain Frontal Cortex BA9	SLC25A17	0.11	-0.01	lasso	5	0.00	3.5e-01	-4.2	-5.2	1.6e-07	0.22	0.08	0.18	FALSE
6	GTEx	Breast Mammary Tissue (Male)	CYP2D6	0.34	-0.01	lasso	6	0.00	3.2e-01	4.6	-5.2	1.7e-07	0.36	0.11	0.10	FALSE
8	GTEx	Breast Mammary Tissue (Female)	DESI1	0.14	0.07	lasso	4	0.11	4.2e-04	-5.3	5.2	2.0e-07	-0.45	0.08	0.12	FALSE
19	NTR	Blood	SYNGR1	0.03	0.03	enet	6	0.03	1.0e-10	4.9	5.2	2.1e-07	0.08	0.30	0.70	FALSE
4	GTEx	Artery Aorta	APOBEC3G	0.40	0.40	lasso	3	0.39	6.3e-23	4.8	5.2	2.2e-07	0.07	0.30	0.70	FALSE
15	GTEx	Skin Sun Exposed Lower leg	APOBEC3G	0.10	0.09	lasso	3	0.06	7.5e-06	4.8	5.2	2.3e-07	0.07	0.31	0.68	FALSE
21	The Cancer Genome Atlas	Colon Adenocarcinoma	MKL1	0.05	0.03	blup	105	0.04	3.9e-03	-5.3	-5.2	2.3e-07	0.11	0.02	0.55	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CBX7	0.09	0.07	bslmm	416	0.06	2.7e-07	3.7	5.2	2.5e-07	-0.04	0.97	0.01	FALSE
9	GTEx	Colon Sigmoid	DESI1	0.21	0.08	enet	6	0.11	1.2e-04	-5.3	5.2	2.5e-07	-0.47	0.40	0.05	FALSE
17	GTEx	Testis	SREBF2	0.25	0.03	lasso	12	0.04	4.6e-03	4.2	5.2	2.6e-07	-0.41	0.62	0.04	FALSE