[Hub]/) : Traits : Arm predicted mass (left) :

chr2:231,628,878-234,145,080

Best TWAS P=4.35e-14 · Best GWAS P=9.1e-12 conditioned to 0.0894

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial EIF4E2 0.09 0.06 lasso 1 0.05 1.7e-04 5.2 -5.2 2.0e-07 0.04 0.78 0.02 FALSE
2 GTEx Heart Atrial Appendage COPS7B 0.22 0.01 lasso 6 0.01 1.3e-01 -5.2 -5.8 6.5e-09 0.66 0.04 0.25 FALSE
3 GTEx Liver PDE6D 0.21 0.10 lasso 4 0.09 1.8e-03 -6.8 -6.8 7.9e-12 0.81 0.01 0.89 TRUE
4 ROSMAP Brain Pre-frontal Cortex NCL 0.16 0.05 lasso 6 0.08 6.1e-10 3.6 5.4 6.8e-08 0.06 0.06 0.94 TRUE
5 YFS Blood EIF4E2 0.06 0.04 enet 27 0.04 2.8e-13 5.2 5.7 1.1e-08 -0.04 0.99 0.01 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma C2orf52 0.28 0.12 lasso 6 0.12 2.0e-06 -5.3 5.4 5.3e-08 -0.04 0.02 0.98 FALSE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EFHD1 0.11 0.01 blup 70 0.03 1.0e-02 5.0 7.5 4.3e-14 -0.03 0.01 0.76 TRUE
8 The Cancer Genome Atlas Brain Lower Grade Glioma GIGYF2 0.02 0.01 lasso 3 0.01 5.3e-02 -5.5 -5.7 1.5e-08 -0.02 0.03 0.88 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma CHRNG 0.04 0.00 blup 58 0.00 1.3e-01 2.8 -5.7 1.1e-08 0.12 0.01 0.31 TRUE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma KCNJ13 0.07 0.07 blup 36 0.06 2.4e-03 -5.6 5.3 1.1e-07 0.02 0.01 0.87 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma GIGYF2 0.04 0.00 blup 103 0.02 2.1e-03 -4.2 -5.2 2.5e-07 0.01 0.04 0.81 FALSE
12 The Cancer Genome Atlas Skin Cutaneous Melanoma C2orf52 0.21 0.20 lasso 1 0.18 1.4e-05 -5.3 5.3 1.2e-07 -0.02 0.01 0.82 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma KCNJ13 0.03 0.00 blup 35 0.01 4.3e-02 5.0 -6.3 3.1e-10 -0.02 0.01 0.56 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma NGEF 0.04 0.03 enet 7 0.03 5.6e-04 5.1 -6.0 2.4e-09 0.00 0.03 0.95 FALSE