[Hub]/) : Traits : Trunk fat mass :

chr20:31,382,860-35,590,249

Best TWAS P=6.6e-13 · Best GWAS P=2.42e-14 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CEP250 0.02 0.00 blup 344 0.00 1.0e-01 3.6 -6.2 6.8e-10 -0.62 0.23 0.11 FALSE
2 CommonMind Brain Pre-frontal Cortex E2F1 0.06 0.01 bslmm 268 0.02 1.6e-03 -5.3 6.1 8.5e-10 0.06 0.04 0.75 TRUE
3 CommonMind Brain Pre-frontal Cortex MMP24 0.02 0.00 bslmm 370 0.00 1.7e-01 5.5 5.9 2.9e-09 0.55 0.06 0.26 FALSE
4 CommonMind Brain Pre-frontal Cortex UQCC 0.07 0.04 lasso 2 0.05 1.4e-06 6.5 -7.2 6.6e-13 -0.88 0.14 0.86 TRUE
5 GTEx Adipose Subcutaneous UQCC1 0.09 0.12 lasso 2 0.11 4.5e-09 6.6 -6.7 2.7e-11 -0.90 0.66 0.34 FALSE
6 GTEx Adipose Subcutaneous PXMP4 0.08 0.03 lasso 4 0.02 6.8e-03 -5.3 5.3 1.3e-07 0.01 0.03 0.71 FALSE
7 GTEx Adipose Visceral Omentum UQCC1 0.15 0.08 lasso 7 0.07 1.6e-04 6.6 -6.4 1.2e-10 -0.87 0.42 0.45 FALSE
8 GTEx Adrenal Gland MMP24-AS1 0.18 0.04 enet 10 0.13 2.2e-05 5.8 -5.4 8.4e-08 -0.74 0.21 0.21 FALSE
9 GTEx Artery Aorta MAP1LC3A 0.19 0.22 enet 36 0.23 4.3e-13 4.2 5.3 1.2e-07 0.29 0.98 0.02 FALSE
10 GTEx Artery Aorta GGT7 0.06 0.00 enet 7 0.02 1.9e-02 -4.4 5.7 1.4e-08 0.14 0.22 0.08 FALSE
11 GTEx Artery Tibial TP53INP2 0.09 0.08 lasso 1 0.07 5.6e-06 6.0 6.0 2.6e-09 0.06 0.01 0.98 FALSE
12 GTEx Artery Tibial EPB41L1 0.07 0.07 enet 10 0.07 1.8e-06 5.2 5.6 1.9e-08 0.39 0.02 0.98 FALSE
13 GTEx Artery Tibial GSS 0.06 0.02 enet 25 0.04 7.7e-04 6.0 6.1 9.8e-10 0.35 0.29 0.08 FALSE
14 GTEx Brain Cerebellum RP4-614O4.12 0.20 0.05 lasso 5 0.03 3.7e-02 4.5 -5.2 1.6e-07 -0.33 0.15 0.20 FALSE
15 GTEx Brain Cortex ERGIC3 0.15 -0.01 lasso 6 0.00 2.8e-01 3.6 5.3 1.1e-07 0.68 0.12 0.10 FALSE
16 GTEx Brain Frontal Cortex BA9 UQCC1 0.16 0.07 lasso 3 0.08 3.7e-03 6.5 -6.8 1.4e-11 -0.80 0.08 0.38 FALSE
17 GTEx Brain Nucleus accumbens basal ganglia EDEM2 0.17 0.00 lasso 4 0.00 2.7e-01 6.0 -6.6 5.1e-11 -0.40 0.08 0.35 FALSE
18 GTEx Brain Putamen basal ganglia E2F1 0.18 0.22 lasso 6 0.21 1.2e-05 -4.9 5.1 2.6e-07 0.01 0.06 0.88 FALSE
19 GTEx Breast Mammary Tissue UQCC1 0.10 0.06 lasso 8 0.08 5.3e-05 -1.9 -5.6 1.7e-08 -0.66 0.44 0.31 TRUE
20 GTEx Breast Mammary Tissue (Male) UQCC1 0.06 0.04 lasso 1 0.02 1.4e-01 6.4 -6.4 1.3e-10 -0.90 0.04 0.13 FALSE
21 GTEx Cells EBV-transformed lymphocytes NCOA6 0.11 0.06 enet 15 0.06 3.9e-03 5.7 -6.2 7.6e-10 -0.31 0.11 0.57 FALSE
22 GTEx Cells Transformed fibroblasts UQCC1 0.23 0.24 lasso 8 0.25 9.4e-19 6.5 -6.5 6.6e-11 -0.88 0.74 0.26 FALSE
23 GTEx Colon Transverse UQCC1 0.11 0.01 lasso 4 0.01 1.0e-01 7.0 -6.4 1.8e-10 -0.48 0.08 0.12 FALSE
24 GTEx Esophagus Mucosa EPB41L1 0.26 0.16 enet 26 0.22 1.9e-14 3.8 -5.8 7.0e-09 -0.36 0.13 0.85 FALSE
25 GTEx Esophagus Mucosa UQCC1 0.13 0.10 enet 10 0.07 1.1e-05 6.4 -6.3 3.9e-10 -0.89 0.39 0.60 FALSE
26 GTEx Esophagus Muscularis ITCH 0.07 0.02 lasso 3 0.01 6.3e-02 5.4 -5.3 1.5e-07 -0.24 0.14 0.70 FALSE
27 GTEx Esophagus Muscularis FER1L4 0.11 0.14 enet 21 0.13 3.4e-08 4.3 -5.3 1.1e-07 -0.36 1.00 0.00 FALSE
28 GTEx Lung UQCC1 0.13 0.08 lasso 5 0.06 1.0e-05 6.6 -6.6 3.5e-11 -0.90 0.40 0.60 FALSE
29 GTEx Muscle Skeletal CBFA2T2 0.05 0.01 enet 15 0.01 2.0e-02 -5.1 5.9 3.7e-09 0.00 0.06 0.92 FALSE
30 GTEx Muscle Skeletal UQCC1 0.10 0.04 enet 19 0.05 1.3e-05 6.1 -5.8 4.9e-09 -0.79 0.59 0.40 FALSE
31 GTEx Muscle Skeletal CEP250 0.09 0.04 lasso 9 0.07 3.6e-07 4.6 -6.0 1.7e-09 -0.79 0.97 0.02 FALSE
32 GTEx Muscle Skeletal GGT7 0.07 0.02 enet 26 0.03 7.2e-04 5.7 5.1 3.1e-07 0.28 0.85 0.09 FALSE
33 GTEx Muscle Skeletal ACSS2 0.04 0.04 enet 12 0.04 3.1e-05 6.0 6.1 1.1e-09 0.29 0.61 0.27 FALSE
34 GTEx Nerve Tibial UQCC1 0.07 0.04 enet 6 0.03 2.7e-03 6.6 -6.6 3.0e-11 -0.88 0.21 0.75 FALSE
35 GTEx Nerve Tibial MMP24-AS1 0.32 0.02 enet 49 0.13 1.3e-09 -1.7 5.6 2.1e-08 0.38 0.04 0.09 FALSE
36 GTEx Skin Sun Exposed Lower leg UQCC1 0.19 0.13 enet 16 0.10 8.1e-09 6.6 -6.6 4.0e-11 -0.84 0.68 0.32 FALSE
37 GTEx Stomach UQCC1 0.09 0.14 lasso 2 0.15 1.9e-07 6.6 -6.1 8.7e-10 -0.86 0.39 0.48 FALSE
38 GTEx Stomach MAP1LC3A 0.10 0.04 enet 10 0.05 1.3e-03 -4.4 5.3 1.2e-07 0.27 0.26 0.27 FALSE
39 GTEx Thyroid MYH7B 0.06 0.03 enet 15 0.06 3.6e-05 5.8 6.2 6.7e-10 0.40 0.75 0.13 FALSE
40 GTEx Thyroid RP4-614O4.12 0.08 0.08 lasso 5 0.07 6.8e-06 -3.9 -5.2 1.9e-07 -0.44 0.94 0.03 FALSE
41 METSIM Adipose UQCC1 0.09 0.04 enet 18 0.05 1.5e-07 6.6 -6.4 1.3e-10 -0.90 0.14 0.86 FALSE
42 NTR Blood UQCC 0.01 0.01 enet 6 0.00 1.6e-02 6.6 -6.5 6.3e-11 -0.89 0.08 0.79 FALSE
43 ROSMAP Brain Pre-frontal Cortex UQCC1 0.05 0.05 lasso 5 0.06 1.7e-08 6.4 -6.0 1.7e-09 -0.84 0.20 0.80 FALSE
44 ROSMAP Brain Pre-frontal Cortex GDF5 0.10 0.13 lasso 2 0.12 2.9e-15 6.5 6.5 6.0e-11 0.90 0.62 0.38 FALSE
45 YFS Blood EIF2S2 0.07 0.07 enet 25 0.06 4.3e-20 -4.3 5.7 1.6e-08 0.02 0.85 0.14 FALSE
46 YFS Blood GGT7 0.07 0.08 lasso 9 0.09 4.3e-28 6.0 -5.3 1.4e-07 -0.26 0.52 0.48 FALSE
47 YFS Blood UQCC 0.21 0.19 lasso 26 0.20 6.4e-64 6.6 -6.4 1.2e-10 -0.88 0.68 0.32 FALSE
48 The Cancer Genome Atlas Bladder Urothelial Carcinoma UQCC 0.03 0.04 blup 67 0.03 2.6e-03 6.5 -6.7 2.7e-11 -0.91 0.02 0.91 FALSE
49 The Cancer Genome Atlas Breast Invasive Carcinoma GGT7 0.02 0.02 lasso 3 0.02 2.2e-04 6.0 -6.0 2.4e-09 -0.09 0.01 0.92 FALSE
50 The Cancer Genome Atlas Breast Invasive Carcinoma UQCC 0.08 0.11 blup 67 0.12 1.1e-22 6.4 -7.1 1.3e-12 -0.89 0.72 0.28 FALSE
51 The Cancer Genome Atlas Colon Adenocarcinoma CBFA2T2 0.13 0.04 lasso 1 0.03 1.1e-02 -5.2 5.2 2.3e-07 0.01 0.02 0.38 FALSE
52 The Cancer Genome Atlas Colon Adenocarcinoma GGT7 0.06 0.05 blup 40 0.05 4.2e-04 5.7 -5.3 1.1e-07 -0.23 0.01 0.88 FALSE
53 The Cancer Genome Atlas Glioblastoma Multiforme UQCC 0.15 0.02 blup 67 0.04 2.0e-02 1.5 -5.3 1.5e-07 -0.74 0.02 0.64 FALSE
54 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CEP250 0.02 0.01 blup 43 0.02 8.0e-04 4.6 5.7 1.2e-08 0.79 0.03 0.83 FALSE
55 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma UQCC 0.05 0.06 blup 66 0.06 3.6e-07 5.9 -6.4 1.2e-10 -0.87 0.13 0.87 FALSE
56 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CEP250 0.03 0.01 blup 43 0.03 2.6e-04 7.6 5.5 3.4e-08 0.77 0.01 0.89 FALSE
57 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma UQCC 0.09 0.10 blup 67 0.10 7.2e-11 6.5 -6.8 8.0e-12 -0.88 0.73 0.27 FALSE
58 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma UQCC 0.08 0.01 lasso 3 0.01 9.0e-02 6.1 -6.6 5.3e-11 -0.72 0.04 0.85 TRUE
59 The Cancer Genome Atlas Brain Lower Grade Glioma GDF5 0.09 0.11 blup 76 0.12 1.0e-13 6.4 5.8 6.3e-09 0.83 0.13 0.87 FALSE
60 The Cancer Genome Atlas Brain Lower Grade Glioma NCOA6 0.04 0.02 blup 65 0.04 6.1e-05 -3.7 -5.2 1.9e-07 -0.09 0.24 0.38 FALSE
61 The Cancer Genome Atlas Brain Lower Grade Glioma UQCC 0.04 0.06 lasso 6 0.05 2.3e-06 6.6 -6.6 5.6e-11 -0.90 0.52 0.48 FALSE
62 The Cancer Genome Atlas Lung Adenocarcinoma UQCC 0.10 0.07 enet 10 0.07 1.5e-08 6.4 -6.3 3.7e-10 -0.89 0.09 0.91 FALSE
63 The Cancer Genome Atlas Lung Squamous Cell Carcinoma UQCC 0.07 0.08 blup 67 0.07 1.1e-08 6.5 -5.5 3.1e-08 -0.82 0.05 0.95 FALSE
64 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma GDF5 0.05 0.02 blup 76 0.04 1.4e-03 6.5 6.8 1.2e-11 0.89 0.03 0.91 FALSE
65 The Cancer Genome Atlas Pancreatic Adenocarcinoma UQCC 0.12 0.03 blup 67 0.09 1.7e-04 6.3 -6.9 4.6e-12 -0.83 0.02 0.89 FALSE
66 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma UQCC 0.22 0.21 lasso 7 0.18 1.9e-07 6.3 -6.8 1.3e-11 -0.84 0.29 0.71 FALSE
67 The Cancer Genome Atlas Prostate Adenocarcinoma FAM83C 0.16 0.10 lasso 4 0.11 2.1e-11 6.2 -6.0 1.5e-09 -0.58 0.11 0.89 FALSE
68 The Cancer Genome Atlas Prostate Adenocarcinoma GDF5 0.05 0.05 lasso 5 0.04 7.2e-05 7.6 6.9 6.4e-12 0.95 0.00 1.00 FALSE
69 The Cancer Genome Atlas Prostate Adenocarcinoma GGT7 0.05 0.02 enet 6 0.03 3.3e-04 6.1 -6.8 7.6e-12 -0.19 0.01 0.97 TRUE
70 The Cancer Genome Atlas Prostate Adenocarcinoma UQCC 0.07 0.10 lasso 8 0.11 1.3e-11 6.4 -6.8 1.0e-11 -0.90 0.33 0.67 FALSE
71 The Cancer Genome Atlas Soft Tissue Sarcoma UQCC 0.07 0.06 blup 66 0.07 5.2e-05 6.5 -6.4 1.1e-10 -0.89 0.02 0.97 TRUE
72 The Cancer Genome Atlas Stomach Adenocarcinoma GDF5 0.09 0.04 enet 13 0.05 2.4e-04 7.6 6.5 7.8e-11 0.85 0.00 0.99 FALSE
73 The Cancer Genome Atlas Stomach Adenocarcinoma NDRG3 0.09 0.06 enet 6 0.05 2.7e-04 -4.1 5.5 3.9e-08 0.01 0.00 0.33 TRUE
74 The Cancer Genome Atlas Stomach Adenocarcinoma UQCC 0.07 0.06 lasso 10 0.06 2.8e-05 6.5 -6.5 9.1e-11 -0.88 0.04 0.95 FALSE
75 The Cancer Genome Atlas Testicular Germ Cell Tumors CEP250 0.10 0.00 blup 43 0.05 9.8e-03 6.1 5.5 2.9e-08 0.73 0.01 0.24 FALSE
76 The Cancer Genome Atlas Thyroid Carcinoma CEP250 0.05 0.03 blup 43 0.04 5.8e-05 4.6 6.0 1.6e-09 0.78 0.12 0.83 FALSE
77 The Cancer Genome Atlas Thyroid Carcinoma GDF5 0.02 0.00 blup 76 0.00 1.9e-01 6.4 6.5 6.2e-11 0.90 0.02 0.88 FALSE
78 The Cancer Genome Atlas Thyroid Carcinoma UQCC 0.15 0.21 blup 67 0.22 1.2e-20 6.4 -6.9 4.0e-12 -0.88 0.43 0.57 FALSE
79 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma UQCC 0.13 0.15 lasso 1 0.11 7.1e-04 5.9 -5.9 4.3e-09 -0.74 0.04 0.65 FALSE