[Hub]/) : Traits : Trunk fat-free mass : ← →

chr12:55,633,142-58,222,672

Best TWAS P=5.16e-17 · Best GWAS P=1.49e-16 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	CommonMind	Brain Pre-frontal Cortex	PRIM1	0.31	0.24	enet	7	0.24	1.1e-28	-8.3	8.4	5.2e-17	-1.00	0.00	1.00	TRUE
23	GTEx	Breast Mammary Tissue (Female)	RPS26	0.20	0.11	lasso	3	0.10	6.6e-04	-5.8	-7.9	3.0e-15	-0.01	0.01	0.87	TRUE
39	GTEx	Muscle Skeletal	SUOX	0.11	0.04	lasso	7	0.04	4.4e-05	-5.8	6.5	6.4e-11	0.02	0.29	0.63	TRUE
14	GTEx	Brain Caudate basal ganglia	RP11-977G19.11	0.31	0.25	lasso	5	0.28	1.2e-08	5.7	-6.2	5.7e-10	-0.01	0.90	0.01	TRUE
12	GTEx	Artery Tibial	RPS26	0.07	0.02	enet	5	0.01	3.5e-02	-6.3	-6.2	7.2e-10	-0.03	0.24	0.16	TRUE
11	GTEx	Artery Tibial	STAT6	0.08	0.03	enet	4	0.02	1.3e-02	-5.9	-6.1	1.0e-09	0.19	0.29	0.05	TRUE
83	The Cancer Genome Atlas	Lung Adenocarcinoma	RAB5B	0.03	0.02	enet	7	0.02	4.3e-03	-6.2	-6.0	2.0e-09	-0.03	0.02	0.26	TRUE
32	GTEx	Esophagus Muscularis	SUOX	0.24	0.19	enet	16	0.15	2.3e-09	-5.8	5.8	8.1e-09	0.05	0.99	0.01	TRUE
21	GTEx	Breast Mammary Tissue	RPS26	0.29	0.05	enet	37	0.12	9.4e-07	-6.3	-7.6	2.7e-14	-0.02	0.22	0.77	FALSE
27	GTEx	Colon Sigmoid	RP11-977G19.11	0.22	0.00	enet	33	0.04	1.5e-02	5.7	-6.8	1.1e-11	0.31	0.11	0.17	FALSE
87	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPS26	0.30	0.20	lasso	4	0.24	3.9e-16	-6.3	-6.7	2.2e-11	-0.04	0.08	0.92	FALSE
97	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RPS26	0.46	0.64	lasso	4	0.65	8.5e-30	-6.3	-6.6	4.1e-11	-0.03	0.16	0.84	FALSE
86	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RPS26	0.22	0.31	lasso	3	0.31	1.6e-35	-6.3	-6.6	4.3e-11	-0.04	0.15	0.85	FALSE
73	The Cancer Genome Atlas	Colon Adenocarcinoma	RPS26	0.43	0.48	lasso	4	0.47	1.8e-30	-6.3	-6.6	4.8e-11	-0.04	0.14	0.86	FALSE
72	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RPS26	0.23	0.40	lasso	2	0.39	1.5e-20	-6.3	-6.5	7.7e-11	-0.04	0.14	0.86	FALSE
61	GTEx	Thyroid	RP11-977G19.11	0.16	0.11	enet	20	0.13	3.5e-10	5.4	-6.5	7.9e-11	-0.02	1.00	0.00	FALSE
84	The Cancer Genome Atlas	Lung Adenocarcinoma	RPS26	0.26	0.45	enet	9	0.47	3.6e-61	-6.3	-6.5	8.0e-11	-0.03	0.16	0.84	FALSE
74	The Cancer Genome Atlas	Esophageal Carcinoma	RPS26	0.19	0.13	lasso	5	0.11	2.4e-04	-6.3	-6.5	9.4e-11	-0.04	0.02	0.96	FALSE
38	GTEx	Muscle Skeletal	RAB5B	0.29	0.32	lasso	4	0.33	1.3e-33	-6.2	6.5	1.0e-10	0.02	0.99	0.01	FALSE
40	GTEx	Muscle Skeletal	AC034102.1	0.28	0.31	lasso	4	0.31	2.3e-31	-6.3	6.5	1.0e-10	0.02	0.99	0.01	FALSE
58	GTEx	Testis	SUOX	0.27	0.18	lasso	14	0.18	1.4e-08	-5.8	6.5	1.0e-10	0.03	0.74	0.25	FALSE
71	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPS26	0.30	0.44	enet	10	0.45	5.2e-104	-6.3	-6.4	1.2e-10	-0.04	0.15	0.85	FALSE
96	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPS26	0.19	0.32	lasso	5	0.34	2.0e-25	-6.3	-6.4	1.2e-10	-0.03	0.23	0.77	FALSE
94	The Cancer Genome Atlas	Soft Tissue Sarcoma	RPS26	0.23	0.31	lasso	3	0.30	2.4e-18	-6.3	-6.4	1.3e-10	-0.04	0.15	0.85	FALSE
92	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPS26	0.33	0.52	enet	9	0.54	5.6e-66	-6.3	-6.4	1.4e-10	-0.03	0.15	0.85	FALSE
50	GTEx	Prostate	SUOX	0.22	0.04	enet	11	0.05	2.3e-02	-5.8	6.4	1.7e-10	0.02	0.10	0.38	FALSE
81	The Cancer Genome Atlas	Brain Lower Grade Glioma	RPS26	0.31	0.53	enet	8	0.55	1.7e-74	-6.3	-6.4	1.7e-10	-0.03	0.19	0.81	FALSE
76	The Cancer Genome Atlas	Glioblastoma Multiforme	RPS26	0.41	0.38	enet	9	0.39	7.9e-13	-6.3	-6.4	1.8e-10	-0.03	0.18	0.82	FALSE
77	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RPS26	0.17	0.29	lasso	4	0.29	6.2e-33	-6.3	-6.4	1.9e-10	-0.03	0.22	0.78	FALSE
79	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RPS26	0.27	0.38	enet	8	0.40	5.0e-24	-6.3	-6.4	2.1e-10	-0.04	0.17	0.83	FALSE
65	METSIM	Adipose	RPS26	0.30	0.40	lasso	5	0.41	7.2e-66	-6.3	-6.3	2.4e-10	-0.03	0.99	0.01	FALSE
70	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RPS26	0.14	0.22	lasso	2	0.23	4.8e-19	-6.3	-6.3	2.4e-10	-0.03	0.20	0.80	FALSE
82	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RPS26	0.18	0.31	lasso	2	0.29	3.9e-14	-6.3	-6.3	2.6e-10	-0.04	0.16	0.84	FALSE
95	The Cancer Genome Atlas	Skin Cutaneous Melanoma	RPS26	0.28	0.15	lasso	2	0.17	3.0e-05	-6.2	-6.3	3.7e-10	-0.03	0.02	0.94	FALSE
93	The Cancer Genome Atlas	Rectum Adenocarcinoma	RPS26	0.24	0.18	lasso	2	0.20	1.9e-05	-6.3	-6.2	4.1e-10	-0.04	0.05	0.55	FALSE
64	METSIM	Adipose	IKZF4	0.04	0.04	enet	3	0.04	1.0e-06	-6.2	-6.2	4.4e-10	-0.03	0.98	0.01	FALSE
101	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	RPS26	0.17	0.19	lasso	4	0.18	1.3e-05	-6.3	-6.2	4.7e-10	-0.03	0.04	0.94	FALSE
29	GTEx	Esophagus Gastroesophageal Junction	SUOX	0.20	0.16	lasso	5	0.19	2.7e-07	-5.8	6.2	4.9e-10	0.03	0.66	0.28	FALSE
4	CommonMind	Brain Pre-frontal Cortex	RPS26	0.48	0.62	lasso	5	0.63	5.9e-99	-6.3	-6.2	5.3e-10	-0.04	0.99	0.01	FALSE
89	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RPS26	0.36	0.44	lasso	7	0.42	2.4e-19	-6.3	-6.2	6.0e-10	-0.03	0.28	0.72	FALSE
33	GTEx	Heart Atrial Appendage	SUOX	0.09	0.10	enet	8	0.09	1.1e-04	-6.3	6.1	1.1e-09	0.02	0.14	0.63	FALSE
90	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RPS26	0.47	0.43	lasso	2	0.44	3.2e-19	-5.8	-6.1	1.2e-09	-0.03	0.30	0.70	FALSE
52	GTEx	Skin Sun Exposed Lower leg	SUOX	0.23	0.30	lasso	3	0.29	1.9e-24	-5.8	6.0	1.8e-09	0.03	1.00	0.00	FALSE
60	GTEx	Thyroid	SUOX	0.37	0.40	lasso	7	0.38	5.4e-31	-5.8	6.0	2.1e-09	0.03	1.00	0.00	FALSE
17	GTEx	Brain Cortex	SUOX	0.16	0.11	lasso	4	0.10	1.1e-03	-5.8	6.0	2.3e-09	0.03	0.07	0.26	FALSE
24	GTEx	Cells Transformed fibroblasts	PAN2	0.09	0.07	lasso	4	0.05	1.7e-04	5.6	6.0	2.5e-09	-0.03	0.90	0.00	FALSE
48	GTEx	Pituitary	RP11-977G19.11	0.47	0.40	lasso	14	0.40	4.5e-11	5.4	-5.9	3.6e-09	0.00	0.99	0.00	FALSE
67	ROSMAP	Brain Pre-frontal Cortex	NABP2	0.12	0.12	lasso	4	0.13	2.7e-16	5.7	5.9	4.0e-09	0.00	1.00	0.00	FALSE
45	GTEx	Nerve Tibial	CNPY2	0.07	0.00	enet	21	0.00	3.2e-01	-6.1	5.9	4.1e-09	0.05	0.10	0.06	FALSE
10	GTEx	Artery Coronary	RP11-977G19.11	0.24	0.14	lasso	13	0.08	1.2e-03	5.4	-5.9	4.7e-09	0.00	0.54	0.02	FALSE
43	GTEx	Nerve Tibial	RPS26	0.12	0.09	enet	7	0.11	3.0e-08	-6.1	-5.8	5.1e-09	-0.05	0.95	0.04	FALSE
26	GTEx	Colon Sigmoid	SUOX	0.23	0.18	lasso	4	0.15	7.9e-06	-5.8	5.8	6.0e-09	0.04	0.38	0.57	FALSE
63	GTEx	Whole Blood	RPS26	0.05	0.05	lasso	1	0.05	3.4e-05	-5.8	-5.8	6.9e-09	-0.03	0.22	0.68	FALSE
51	GTEx	Skin Not Sun Exposed Suprapubic	SUOX	0.10	0.14	lasso	2	0.12	2.5e-07	-5.8	5.8	7.2e-09	0.03	0.49	0.44	FALSE
54	GTEx	Skin Sun Exposed Lower leg	CNPY2	0.10	0.08	lasso	5	0.08	5.9e-07	5.7	5.8	7.4e-09	0.01	0.96	0.01	FALSE
75	The Cancer Genome Atlas	Glioblastoma Multiforme	PAN2	0.08	0.04	blup	31	0.03	4.4e-02	5.4	5.7	9.0e-09	0.02	0.01	0.57	FALSE
35	GTEx	Liver	STAT2	0.32	0.17	lasso	13	0.14	9.9e-05	5.7	5.7	9.1e-09	0.01	0.82	0.01	FALSE
46	GTEx	Pancreas	IL23A	0.23	0.01	lasso	13	0.04	1.1e-02	5.7	5.7	9.1e-09	0.01	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PAN2	0.05	0.07	lasso	3	0.06	5.4e-08	5.7	5.7	9.3e-09	0.01	1.00	0.00	FALSE
8	GTEx	Artery Aorta	RP11-977G19.11	0.26	0.28	lasso	14	0.28	5.3e-16	5.7	-5.7	9.3e-09	-0.01	1.00	0.00	FALSE
13	GTEx	Artery Tibial	RP11-977G19.11	0.16	0.18	lasso	12	0.18	6.1e-14	5.7	-5.7	9.3e-09	-0.01	1.00	0.00	FALSE
30	GTEx	Esophagus Gastroesophageal Junction	RP11-977G19.11	0.18	0.14	lasso	13	0.07	2.0e-03	5.7	-5.7	9.3e-09	-0.01	0.65	0.02	FALSE
59	GTEx	Thyroid	IL23A	0.07	0.04	lasso	10	0.00	1.9e-01	5.7	5.7	9.3e-09	0.01	0.39	0.03	FALSE
49	GTEx	Pituitary	CNPY2	0.32	0.19	lasso	11	0.12	6.8e-04	5.7	5.7	9.4e-09	0.01	0.29	0.06	FALSE
57	GTEx	Stomach	RPS26	0.16	0.08	enet	5	0.05	1.8e-03	-5.8	-5.7	1.0e-08	-0.03	0.11	0.46	FALSE
36	GTEx	Lung	RP11-977G19.11	0.07	0.03	lasso	11	0.04	5.1e-04	5.4	-5.7	1.1e-08	-0.01	0.79	0.01	FALSE
16	GTEx	Brain Cerebellum	RP11-977G19.11	0.17	0.19	lasso	14	0.18	5.4e-06	5.7	-5.7	1.2e-08	-0.01	0.65	0.02	FALSE
18	GTEx	Brain Hypothalamus	RP11-977G19.11	0.32	0.20	lasso	6	0.23	4.4e-06	5.4	-5.6	1.8e-08	-0.02	0.77	0.02	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CNPY2	0.06	0.05	lasso	8	0.05	2.3e-06	5.5	-5.6	2.0e-08	0.00	0.99	0.00	FALSE
41	GTEx	Nerve Tibial	IL23A	0.06	0.08	lasso	10	0.07	1.6e-05	5.6	5.6	2.2e-08	-0.02	0.87	0.00	FALSE
6	GTEx	Adrenal Gland	RP11-977G19.11	0.19	0.16	lasso	15	0.09	3.9e-04	5.4	-5.6	2.3e-08	0.00	0.86	0.01	FALSE
37	GTEx	Lung	CNPY2	0.05	0.03	lasso	4	0.00	1.7e-01	5.6	5.6	2.6e-08	-0.02	0.34	0.03	FALSE
85	The Cancer Genome Atlas	Lung Adenocarcinoma	STAT2	0.02	0.02	blup	21	0.01	9.6e-03	5.4	5.6	2.8e-08	0.01	0.01	0.86	FALSE
28	GTEx	Colon Transverse	RP11-977G19.11	0.18	0.05	lasso	2	0.00	1.9e-01	5.4	-5.5	2.9e-08	0.00	0.13	0.04	FALSE
69	YFS	Blood	SUOX	0.11	0.09	bslmm	269	0.09	3.4e-27	-5.8	5.5	3.0e-08	0.02	1.00	0.00	FALSE
91	The Cancer Genome Atlas	Prostate Adenocarcinoma	COQ10A	0.03	0.03	lasso	2	0.03	9.1e-04	5.4	-5.5	3.1e-08	0.00	0.01	0.92	FALSE
42	GTEx	Nerve Tibial	STAT2	0.08	0.05	lasso	3	0.03	5.0e-03	5.6	-5.5	3.2e-08	0.02	0.37	0.04	FALSE
99	The Cancer Genome Atlas	Thyroid Carcinoma	RPS26	0.33	0.51	enet	19	0.50	7.3e-56	-6.3	-5.5	3.3e-08	-0.04	0.15	0.85	FALSE
25	GTEx	Cells Transformed fibroblasts	RP11-977G19.11	0.11	0.07	enet	22	0.05	9.5e-05	5.4	-5.5	4.0e-08	-0.01	0.99	0.00	FALSE
44	GTEx	Nerve Tibial	RP11-977G19.11	0.15	0.18	enet	23	0.20	7.7e-14	5.4	-5.5	4.4e-08	-0.01	1.00	0.00	FALSE
56	GTEx	Stomach	SUOX	0.15	0.17	enet	8	0.09	6.7e-05	-5.8	5.5	4.5e-08	0.03	0.68	0.24	FALSE
78	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RPS26	0.50	0.45	enet	13	0.52	1.4e-67	-6.3	-5.5	4.8e-08	-0.05	0.27	0.73	FALSE
31	GTEx	Esophagus Mucosa	RP11-977G19.11	0.07	0.09	lasso	1	0.07	1.5e-05	5.4	-5.4	5.2e-08	0.00	0.95	0.00	FALSE
22	GTEx	Breast Mammary Tissue	RP11-977G19.11	0.11	0.08	lasso	8	0.04	2.5e-03	5.4	-5.4	5.3e-08	-0.02	0.30	0.04	FALSE
20	GTEx	Brain Putamen basal ganglia	RP11-973D8.4	0.18	0.21	lasso	1	0.14	4.3e-04	5.4	-5.4	5.6e-08	-0.03	0.17	0.05	FALSE
80	The Cancer Genome Atlas	Brain Lower Grade Glioma	IL23A	0.03	0.04	lasso	7	0.04	2.9e-05	5.4	5.4	5.7e-08	0.00	0.01	0.98	FALSE
68	YFS	Blood	CNPY2	0.02	0.02	lasso	1	0.02	5.8e-07	5.4	5.4	6.1e-08	0.02	0.99	0.00	FALSE
19	GTEx	Brain Nucleus accumbens basal ganglia	RP11-977G19.11	0.30	0.12	lasso	10	0.08	4.6e-03	5.6	-5.4	6.5e-08	-0.02	0.27	0.05	FALSE
88	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ESYT1	0.16	0.02	blup	33	0.05	5.5e-03	1.6	-5.4	6.5e-08	0.03	0.01	0.67	FALSE
98	The Cancer Genome Atlas	Thyroid Carcinoma	IL23A	0.03	0.03	blup	22	0.02	1.8e-03	5.4	5.4	6.6e-08	0.02	0.01	0.79	FALSE
55	GTEx	Spleen	SUOX	0.34	0.31	enet	15	0.28	5.4e-08	-5.8	5.4	6.7e-08	0.03	0.14	0.76	FALSE
62	GTEx	Thyroid	CNPY2	0.06	0.02	lasso	10	0.02	2.1e-02	5.4	5.4	6.9e-08	0.01	0.58	0.02	FALSE
100	The Cancer Genome Atlas	Thyroid Carcinoma	STAT6	0.04	0.01	blup	47	0.01	2.3e-02	-3.9	-5.4	7.6e-08	0.02	0.06	0.29	FALSE
53	GTEx	Skin Sun Exposed Lower leg	RP11-977G19.11	0.15	0.09	lasso	11	0.08	1.9e-07	5.4	-5.3	8.8e-08	-0.02	1.00	0.00	FALSE
47	GTEx	Pituitary	IL23A	0.27	0.11	lasso	9	0.12	8.0e-04	5.4	5.3	9.6e-08	0.01	0.22	0.07	FALSE
5	GTEx	Adipose Subcutaneous	RP11-977G19.11	0.12	0.10	lasso	7	0.09	7.5e-08	5.6	-5.3	1.4e-07	0.01	1.00	0.00	FALSE
15	GTEx	Brain Cerebellum	SUOX	0.24	0.20	lasso	6	0.20	1.2e-06	-5.8	5.2	1.7e-07	0.04	0.08	0.86	FALSE
7	GTEx	Artery Aorta	SUOX	0.36	0.30	lasso	7	0.35	3.8e-20	-5.8	5.2	2.0e-07	0.05	1.00	0.00	FALSE
9	GTEx	Artery Aorta	CNPY2	0.13	0.03	lasso	14	0.03	5.9e-03	2.7	5.2	2.4e-07	0.01	0.19	0.04	FALSE
66	NTR	Blood	OBFC2B	0.01	0.00	bslmm	248	0.00	3.6e-02	2.0	-5.1	2.9e-07	0.00	0.05	0.02	FALSE
34	GTEx	Liver	DGKA	0.33	0.03	lasso	15	0.13	1.4e-04	5.4	5.1	3.0e-07	0.08	0.09	0.05	FALSE