TWAS hub - OBFC2B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0112	0.0059	0.0120	-0.001	0.002	0.000	0.003	-0.001	0.64	0.083	0.220	0.036	0.86
2	TCGA	Cervical Squamous Cell Carcinoma	0.0700	0.0360	0.0092	-0.002	0.000	-0.006	NA	-0.006	0.41	0.300	0.850	NA	0.98
3	TCGA	Testicular Germ Cell Tumors	0.1770	0.0770	0.0078	0.005	0.026	0.020	NA	0.014	0.20	0.041	0.066	NA	0.10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Stomach or abdominal pain in last month	6.0	7.4	12.6	3.5	3.0	0.9
Forced vital capacity (FVC), Best measure	5.7	20.9	39.3	-6.3	-4.8	-0.2
Medication: Aspirin	5.1	6.7	9.0	3.0	2.5	2.2
Forced vital capacity (FVC)	4.5	17.5	32.6	-5.7	-4.4	-0.8
Medication: Aspirin	4.5	6.0	8.3	2.9	2.2	2.2
Fed-up feelings	4.3	7.8	16.4	2.5	0.9	-4.0
Illness, injury, bereavement, stress in last 2 years	4.2	5.1	9.7	-3.1	-2.3	0.7
Heart attack	4.1	5.3	7.9	2.5	2.8	1.3
Forced expiratory volume in 1-second (FEV1), predicted	4.0	8.3	18.0	-4.2	-2.6	-0.3
Ovarian Cancer	3.9	5.2	9.8	-2.4	-3.1	-0.2
Chronic bronchitis/emphysema (mother)	3.8	4.5	7.5	-2.7	-2.3	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	3.6	11.4	21.7	-4.7	-3.5	-0.3
Neuroticism score	3.5	7.3	12.8	2.7	1.3	-3.6
Pulse wave Arterial Stiffness index	3.4	4.0	7.0	-0.9	-2.6	-2.0
Overall health rating	3.3	7.0	11.9	3.4	2.7	-1.3
Mother’s age at death	3.3	4.2	8.8	-1.8	-3.0	0.8
Neuroticism	3.2	7.8	15.5	2.6	1.1	-3.9
Number of children fathered	3.2	3.6	5.8	-2.4	-1.8	-1.2
Loneliness, isolation	3.2	4.4	7.4	2.7	1.6	-1.8
Sensitivity / hurt feelings	3.1	5.3	7.1	2.7	2.1	-2.1
Medication: Cholesterol lowering	3.1	4.8	6.5	2.5	2.0	2.0
Heart attack/myocardial infarction (self-reported)	3.1	4.1	5.9	2.1	2.4	1.3
Frequency of tiredness / lethargy in last 2 weeks	3.0	4.9	8.1	2.8	2.0	-1.6
Standing height	3.0	30.1	61.2	-7.8	-5.4	-0.5
Depressed Affect (Nagel 2018)	2.9	6.1	10.7	3.3	1.3	-2.4
Hair/balding pattern: Pattern 4	2.9	7.0	10.6	-3.3	-3.1	1.0
Ever had prostate specific antigen (PSA) test	2.9	3.3	5.5	-2.0	-2.4	0.7
Height	2.8	53.4	112.9	-10.6	-6.8	0.9
Trunk fat-free mass	2.8	16.1	26.3	-5.1	-4.6	-0.7
Forced expiratory volume in 1-second (FEV1)	2.8	9.4	17.2	-4.2	-3.3	-0.5
Trunk predicted mass	2.8	16.2	26.4	-5.1	-4.6	-0.7
Whole body fat-free mass	2.8	15.9	24.8	-5.0	-4.7	-0.7
Whole body water mass	2.8	15.9	24.4	-4.9	-4.8	-0.8
Pack years adult smoking proportion	2.7	4.2	6.3	2.5	1.6	-1.9
Worrier / anxious feelings	2.7	5.2	9.5	1.9	1.5	-3.1
Tinnitus: Yes, but not now, but have in the past	2.6	2.7	6.3	-1.4	-2.5	-0.2
Leg fat-free mass (right)	2.6	13.7	20.7	-4.5	-4.5	-0.7
Leg predicted mass (right)	2.6	13.7	20.7	-4.6	-4.5	-0.8
Basal metabolic rate	2.6	14.2	21.2	-4.6	-4.5	-0.9
Leg fat-free mass (left)	2.5	13.1	19.5	-4.4	-4.4	-0.8
Pulse wave peak to peak time	2.5	2.9	4.9	0.4	2.2	1.9
Leg predicted mass (left)	2.4	12.9	19.4	-4.4	-4.3	-0.8
Glaucoma (self-reported)	2.4	2.9	5.6	-2.4	-1.7	0.2
Arm fat-free mass (right)	2.4	12.2	18.3	-4.3	-4.3	-0.4
Pack years of smoking	2.4	3.6	5.7	2.4	1.5	-1.7
Neuroticism (Nagel 2018)	2.3	5.5	8.1	2.7	1.0	-2.8
Worry (Nagel 2018)	2.3	4.9	9.0	2.2	0.9	-3.0
Blood Red Count	2.3	22.6	50.0	7.1	4.2	-0.0
Age started oral contraceptive pill	2.3	2.9	6.1	2.5	1.6	-0.0
Average weekly spirits intake	2.2	2.7	4.1	2.0	0.7	1.9
Angina	2.2	2.9	4.2	2.0	1.4	1.6
Had other major operations	2.2	2.7	3.5	-1.3	-1.9	-1.8
Mouth/teeth dental problems	2.2	3.4	6.1	-2.0	-2.5	-0.5
Angina (self-reported)	2.2	2.9	4.0	2.0	1.4	1.6
Medication: Ibuprofen	2.2	2.6	3.5	-1.9	-1.8	-1.1
Number of operations (self-reported)	2.2	3.3	6.2	-1.3	-2.5	-1.4
Age at First Birth	2.1	3.0	6.0	-1.2	-1.3	2.4
Serious illness, injury or assault to yourself	2.1	2.5	4.0	2.0	1.6	-1.0
Weight	2.1	10.1	15.9	-3.6	-4.0	-1.1
Arm fat-free mass (left)	2.1	10.9	16.1	-3.9	-4.0	-1.2
Primary Biliary Cirrhosis	2.0	2.8	7.4	2.7	0.9	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.0	2.7	7.1	0.8	0.5	-2.7
Medication: Simvastatin	2.0	2.9	6.6	2.6	1.4	0.5
Ever had bowel cancer screening	2.0	2.3	5.4	-0.9	-2.3	-0.9
Arm predicted mass (left)	2.0	10.0	15.5	-3.7	-3.9	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.3	7.5	2.7	2.0	1.2
Hayfever/allergic rhinitis (self-reported)	1.9	2.5	4.6	-1.6	-2.1	0.6
Pulse rate, automated reading	1.9	6.2	12.1	3.5	2.5	0.6
Risk taking	1.9	2.8	4.1	-2.0	-1.3	1.6
HbA1C	1.8	2.0	3.4	1.8	1.2	-1.0
Neuroticism (2016)	1.8	2.5	7.2	0.6	-0.3	-2.7
Rheumatoid Arthritis	1.8	2.5	3.6	1.9	1.5	1.2
Vitamin and mineral supplements	1.8	2.4	5.8	-0.2	-1.2	-2.4
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.0	6.4	2.5	1.5	1.8
Nervous feelings	1.8	3.4	4.6	2.0	1.3	-2.2
Noisy workplace	1.8	2.2	5.7	0.6	0.7	2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	6.6	0.0	-0.5	-2.6
Arm predicted mass (right)	1.8	9.3	14.6	-3.6	-3.8	-0.6
Cholesterol lowering medication	1.8	2.7	7.0	2.6	1.1	0.0
Tanning	1.7	21.3	32.3	-5.7	-5.6	-0.3
High cholesterol (Self-reported)	1.7	2.9	7.3	2.7	1.0	0.7
Respiratory disease	1.6	3.6	6.0	-2.5	-2.2	0.1
Average weekly fortified wine intake	1.6	1.9	3.6	-1.4	-1.9	0.2
Mouth/teeth dental problems: Dentures	1.6	2.6	3.9	2.0	2.0	0.4
Tense / ‘highly strung’	1.6	2.6	3.7	1.9	0.7	-1.9
Medication: Blood pressure	1.6	2.8	5.5	-1.0	-1.3	2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.8	3.7	1.9	1.4	0.1
Eye problems/disorders: Glaucoma	1.6	1.9	4.2	-2.1	-1.2	0.2
Ever had hysterectomy (womb removed)	1.5	1.7	3.1	-0.8	-1.8	1.1
Alcohol intake versus 10 years previously	1.5	2.2	4.1	-1.5	-2.0	-0.1
Birth weight	1.5	3.3	5.3	-2.3	-2.1	0.5
Average weekly champagne plus white wine intake	1.5	2.1	2.8	-1.7	-1.5	1.1
Medication: Bendroflumethiazide	1.5	2.3	5.9	-0.4	-0.9	2.4
Sitting height	1.4	9.7	19.6	-4.4	-2.7	-1.4
Falls in the last year	1.4	1.9	2.7	1.6	1.5	0.9
Worry too long after embarrassment	1.4	2.3	3.8	1.2	1.3	-1.9
Number of full sisters	1.4	1.7	4.2	0.5	0.8	2.0
Family relationship satisfaction	1.4	1.8	3.3	-1.2	-0.8	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	2.5	-1.6	-1.4	0.5
Qualifications: nursing, teaching	1.4	2.1	3.1	-1.8	-1.8	-0.2
Financial situation satisfaction	1.4	1.7	3.1	1.8	1.4	0.3
Illnesses of father: High blood pressure	1.4	1.8	2.9	-1.5	-1.7	0.4
Depression (Nagel 2018)	1.3	2.0	3.3	1.8	1.2	-1.1
Schizophrenia vs Biploar Disorder	1.3	1.7	5.1	2.3	0.0	0.0
Body Mass Index (BMI) (2010)	1.3	1.8	4.2	0.5	1.0	-2.0
Relative age of first facial hair	1.3	2.7	4.8	1.4	2.2	1.1
Peak expiratory flow (PEF)	1.3	3.1	6.6	-2.6	-1.6	0.3
Number of full brothers	1.3	1.7	3.1	1.3	1.8	-0.4
Friendships satisfaction	1.3	1.6	1.9	1.2	1.4	-1.2
Medication: Atorvastatin	1.3	1.7	4.2	2.1	0.8	0.4
Lung FVC	1.2	6.1	9.2	-2.9	-3.0	0.9
Qualifications: CSEs or equivalent	1.2	1.6	3.3	0.7	1.1	-1.8
Chronic bronchitis/emphysema (father)	1.2	1.4	3.9	0.2	0.4	-2.0
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	3.5	1.9	1.4	-0.4
Hip circumference	1.2	5.2	9.6	-2.2	-3.1	-1.1
Pulse rate	1.2	2.0	2.4	1.6	1.3	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	4.8	-0.7	-0.3	-2.2
Blood clot in the leg (DVT)	1.2	1.6	4.1	0.8	-0.4	-2.0
Gout (self-reported)	1.2	1.7	2.4	-1.5	-1.5	0.8
Emphysema/chronic bronchitis	1.2	1.3	3.0	0.9	0.5	-1.7
Medication: Seretide 50 evohaler	1.2	1.4	2.5	1.3	1.6	-0.2
Comparative height size at age 10	1.2	6.4	11.5	-3.4	-2.7	0.6
Guilty feelings	1.2	1.9	2.6	-1.4	-1.6	-1.1
Ever taken oral contraceptive pill	1.2	1.4	3.9	-0.2	0.4	2.0
Medication: Lisinopril	1.2	1.5	2.9	-1.3	-1.7	-0.0
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	4.2	0.6	-0.3	-2.0
Heart disease (siblings)	1.2	1.5	2.5	1.4	0.0	1.6
Lupus	1.1	1.6	2.5	-1.3	-0.9	1.6
Type 2 Diabetes (T2D) (2018)	1.1	2.0	4.7	1.2	-0.0	-2.2
Hayfever, allergic rhinitis or eczema	1.1	2.3	4.5	-2.1	-1.5	-0.2
Fluid intelligence score	1.1	2.3	3.5	-0.7	-1.6	-1.9
Hair/balding pattern: Pattern 3	1.1	1.7	2.4	-0.7	-1.5	-1.4
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.5	1.8	-1.1	-1.1	-1.4
Pulse wave reflection index	1.1	1.3	2.2	-0.6	-1.2	-1.5
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	5.4	-0.5	-0.0	-2.3
Alcohol intake frequency.	1.1	2.5	3.0	1.7	1.4	-1.6
Handedness (chirality/laterality): Left-handed	1.1	1.3	1.6	1.2	0.9	-1.3
Back pain experienced in last month	1.1	1.6	2.7	1.3	1.6	-0.6
Average weekly beer plus cider intake	1.1	1.6	3.1	-1.8	-1.2	0.5
Alcohol drinker status: Previous	1.1	1.3	2.9	-0.4	-0.9	-1.7
Verbal and Numeric Reasoning (VNR)	1.0	2.5	4.1	-0.9	-1.6	-2.0
Allergy or Eczema	1.0	2.6	4.2	-1.9	-2.0	-0.0
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.3	1.2	0.7	-1.5
Supplements: Zinc	1.0	1.0	1.8	-1.3	-1.1	-0.2
Past tobacco smoking	1.0	1.9	2.8	1.7	1.6	-0.5
Exposure to tobacco smoke outside home	1.0	1.3	2.5	1.6	1.2	-0.1
Qualifications: College or University degree	1.0	3.2	4.8	-2.0	-2.2	-1.0
Medication: Allopurinol	1.0	1.3	2.3	-1.5	-1.2	0.4
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.3	3.1	0.8	0.2	1.8
Illnesses of father: Heart disease	1.0	1.4	1.5	1.2	1.2	1.1
Heel T-Score	0.9	7.2	13.5	3.7	2.2	1.8
Chronotype (morning person)	0.9	2.0	2.6	-1.6	-1.6	0.9
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	1.3	1.1	0.9	1.0
Relative age voice broke	0.9	1.3	2.6	1.1	1.6	-0.2
Waist circumference	0.9	3.2	6.0	-1.4	-2.5	-1.3
Alcohol usually taken with meals	0.9	1.5	2.9	-0.4	-1.7	1.2
Hair/balding pattern: Pattern 2	0.9	1.1	1.7	1.0	1.3	0.8
Depression (self-reported)	0.9	1.0	2.1	1.4	0.4	-0.9
Length of working week for main job	0.9	1.0	1.8	1.0	1.4	-0.2
Birth weight of first child	0.9	1.6	3.6	-1.1	-1.9	0.2
Mouth/teeth dental problems: Loose teeth	0.9	1.0	2.8	0.4	1.7	0.3
Medication: Omeprazole	0.9	1.1	2.7	-0.2	-1.6	-0.8
Suffer from ‘nerves’	0.9	1.4	3.2	-0.5	-0.9	-1.8
Chest pain or discomfort	0.9	1.3	1.4	1.2	1.2	-1.1
Mood swings	0.9	1.6	2.7	1.5	0.0	-1.6
Intelligence (Savage-Jansen 2018)	0.8	2.5	3.5	-1.2	-1.6	-1.9
LDL Cholesterol	0.8	1.2	2.2	0.9	0.7	-1.5
Hand grip strength (left)	0.8	2.0	3.8	-2.0	-1.4	0.5
Severe depression (siblings)	0.8	0.9	1.8	0.8	0.3	1.3
Multivitamins +/- minerals	0.8	1.0	2.2	0.2	0.8	1.5
Impedance of leg (left)	0.8	3.9	8.0	1.6	2.8	1.1
Trunk fat mass	0.8	3.3	5.9	-2.0	-2.4	-0.3
Financial difficulties in last 2 years	0.8	1.0	1.5	1.2	0.8	-1.0
Whole body fat mass	0.8	3.2	6.2	-1.8	-2.5	-0.3
Commuting to job workplace: Car/motor vehicle	0.8	0.9	1.8	0.7	0.7	1.4
Knee pain experienced in last month	0.8	1.2	2.0	-1.2	-1.4	-0.4
Smoking status: Previous	0.8	1.2	1.9	-1.1	-1.4	0.5
Miserableness	0.8	1.4	1.9	1.3	0.7	-1.4
Pain type(s) experienced in last month: Hip pain	0.8	1.0	1.5	-1.2	-0.7	-0.9
Unable to work because of sickness or disability	0.8	1.0	1.8	1.3	1.1	0.0
Crohns Disease (2017)	0.7	1.6	2.7	1.7	1.3	-0.7
Coronary Artery Disease (CAD)	0.7	0.9	2.6	1.6	0.0	0.0
Blood Eosinophil Count	0.7	5.7	9.6	-3.1	-2.7	0.1
Impedance of leg (right)	0.7	3.4	7.0	1.5	2.6	1.0
Hand grip strength (right)	0.7	2.0	3.6	-1.9	-1.5	0.4
Hearing difficulty/problems with background noise	0.7	1.1	2.7	0.6	0.5	-1.6
Diabetes (self-reported)	0.7	1.1	1.6	1.3	0.2	-1.2
Medication: Lansoprazole	0.7	0.8	1.3	0.9	0.6	-1.1
Arm fat mass (right)	0.7	2.8	4.8	-1.5	-2.2	-1.2
Health satisfaction	0.7	0.9	1.5	1.2	0.7	-0.8
Migraine (self-reported)	0.7	0.9	1.6	-1.3	-0.7	0.7
Leg pain on walking	0.7	0.9	1.3	0.1	1.1	-1.2
Long-standing illness, disability or infirmity	0.7	1.0	1.9	1.4	0.8	-0.8
Diabetes diagnosed by doctor	0.7	1.2	2.1	1.1	0.3	-1.4
Medication for cholesterol	0.7	1.1	3.1	-1.8	0.3	0.4
Osteoporosis (self-reported)	0.7	0.9	1.7	0.4	0.9	1.3
Arm fat mass (left)	0.7	2.8	5.4	-1.4	-2.3	-1.1
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.6	0.6	1.3	-0.7
Fractured/broken bones in last 5 years	0.7	0.9	2.6	-0.1	-0.3	-1.6
Alzheimer’s Disease (in father)	0.6	0.7	1.0	-0.6	-1.0	-0.8
Ulcerative Colitis (UC)	0.6	1.1	2.6	0.1	-0.8	-1.6
Reaction Time	0.6	1.1	2.0	-1.4	-1.1	0.2
Cardiovascular Disease	0.6	2.0	5.1	2.3	0.7	0.5
Hearing difficulty/problems: Yes	0.6	0.9	1.5	-0.3	-1.0	-1.2
Diabetes (mother)	0.6	0.7	1.7	0.2	1.3	-0.6
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.4	1.2	0.6	0.6
Medication: Levothyroxine sodium	0.6	1.1	1.4	1.2	0.7	-1.2
Medication: Ramipril	0.6	0.8	1.2	1.1	0.9	0.6
Happiness	0.6	0.7	2.1	0.2	-0.0	-1.4
High blood pressure (siblings)	0.6	0.9	2.1	0.7	-0.1	-1.4
Medication for pain relief, constipation, heartburn	0.6	1.1	2.8	-1.7	-0.6	-0.3
Hearing aid user	0.6	0.7	1.4	0.2	-1.2	0.8
Supplements: Fish oil (including cod liver oil)	0.6	0.7	1.0	-0.9	-0.7	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	1.5	0.2	-0.9	-1.2
Current tobacco smoking	0.5	0.8	1.3	1.0	1.2	0.3
Supplements: Glucosamine	0.5	0.6	1.2	-0.5	-0.6	1.1
Had menopause	0.5	0.6	1.2	0.9	0.2	-1.1
Qualifications: A levels/AS levels or equivalent	0.5	1.1	3.0	-0.6	-0.0	-1.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.0	1.0	0.7	0.4
Prospective memory result	0.5	0.6	1.5	0.6	1.2	0.2
Exposure to tobacco smoke at home	0.5	0.5	1.0	-1.0	-0.7	-0.2
Breastfed as a baby	0.5	0.7	1.4	-1.2	-0.3	-0.7
Eye problems/disorders: None of the above	0.5	0.6	1.7	-0.2	0.1	-1.3
Supplements: Vitamin C	0.5	0.6	1.0	0.2	1.0	0.9
Asthma (self-reported)	0.5	1.1	1.7	-1.3	-1.1	0.5
Illnesses of father: None of the above (group 1)	0.5	0.7	1.0	-1.0	-1.0	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.0	-1.4	-0.9	-0.2
Leg fat mass (left)	0.5	1.8	3.9	-1.2	-2.0	-0.3
Irritable Bowel Disease (IBD)	0.4	0.9	1.3	1.1	0.6	-1.0
Crohns Disease (2012)	0.4	0.7	2.2	1.5	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.5	-1.2	0.0	0.0
Blood White Count	0.4	3.0	7.1	2.7	1.3	-0.4
Waist Hip Ratio (WHR)	0.4	1.9	2.7	-1.4	-1.6	-1.0
Number of treatments/medications taken	0.4	0.8	1.6	0.5	-0.6	1.3
Diabetes (father)	0.4	0.5	0.8	-0.4	0.9	0.7
Maternal smoking around birth	0.4	0.6	1.2	-1.1	-0.8	-0.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.1	-0.4	-1.1	0.0
High blood pressure (mother)	0.4	0.6	1.5	-0.4	-0.2	-1.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.6	0.5	0.7	-0.8
Allergy	0.4	0.9	1.5	1.2	0.8	0.7
Pain all over the body in last month	0.4	0.4	0.6	0.6	0.4	-0.8
Asthma	0.4	0.7	1.1	-1.1	-1.0	0.2
Loud music exposure frequency	0.4	0.4	1.2	0.2	0.1	-1.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.3	0.2	0.6	1.1
Headache pain in last month	0.4	0.8	1.3	0.6	0.8	-1.1
Medication: Amlodipine	0.4	0.5	0.8	-0.6	-0.6	0.9
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.1	0.2	-0.8	-1.1
Age at first live birth	0.4	0.7	0.9	-1.0	-0.9	0.6
Neck or shoulder pain in last month	0.4	0.6	1.1	1.1	0.8	0.3
Mean time to correctly identify matches	0.4	0.7	1.3	-1.1	-0.9	0.2
Leg fat mass (right)	0.4	1.5	3.5	-1.1	-1.9	-0.1
Commuting to job workplace: Walk	0.4	0.4	0.8	0.7	0.2	0.9
Eye problems/disorders: Cataract	0.4	0.4	1.1	-0.2	-0.3	1.1
Number of self-reported non-cancer illnesses	0.4	0.6	1.8	-0.1	-1.3	0.4
Commuting to job workplace: Public transport	0.4	0.4	1.2	-0.2	-1.1	-0.1
Medication: Paracetamol	0.4	0.6	1.6	1.2	-0.0	0.3
Ever smoked	0.4	0.6	0.7	-0.8	-0.7	0.8
Vascular/heart problems diagnosed by doctor	0.4	1.1	1.9	-1.4	0.1	-1.2
Basal cell carcinoma (self-reported)	0.4	0.5	0.9	-1.0	-0.3	-0.6
Triglycerides	0.3	0.5	1.4	-0.1	-0.2	-1.2
Medication: Co-codamol	0.3	0.3	0.6	-0.4	-0.3	0.8
Age when periods started (menarche)	0.3	0.6	1.6	-0.5	-0.1	-1.3
Body mass index (BMI)	0.3	1.1	2.6	-0.2	-1.6	-0.8
Qualifications: None of the above	0.3	0.7	1.3	0.2	1.1	0.8
Number of live births	0.3	0.5	0.7	-0.8	-0.2	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.6	-0.8	-0.7	-0.2
Heart disease (mother)	0.3	0.4	1.0	0.3	-0.1	1.0
Hypertension (Self-reported)	0.3	0.7	1.8	0.5	-1.3	0.5
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.1	0.6	1.0	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.0	-0.1	-0.1	1.0
Breast cancer (self-reported)	0.3	0.4	0.6	0.7	-0.8	-0.1
Smoking status: Current	0.3	0.5	1.0	0.8	1.0	-0.1
Medication: Blood pressure	0.3	0.6	1.1	1.0	-0.9	-0.2
Alcohol drinker status: Never	0.3	0.4	0.9	-0.0	0.5	-0.9
Ever depressed for a whole week	0.3	0.3	0.6	0.5	0.8	-0.3
Commuting to job workplace: Cycle	0.3	0.3	0.9	0.3	0.9	-0.0
Myopia	0.3	0.4	0.5	0.5	0.7	-0.7
Pain experienced in last month	0.3	0.6	1.6	-0.3	-0.2	1.2
Supplements: Calcium	0.3	0.3	0.6	-0.8	-0.3	0.4
Impedance of whole body	0.3	1.7	4.3	0.8	2.1	0.3
Alzheimer’s Disease (in mother)	0.2	0.2	0.7	0.8	-0.1	0.1
Alzheimer’s Disease (including proxy)	0.2	0.2	0.4	0.1	-0.6	-0.6
Major Depression (MDD)	0.2	0.3	0.8	0.9	0.0	0.0
Smoking Status	0.2	0.4	0.6	-0.7	-0.8	-0.1
Hair Pigment	0.2	6.6	11.6	3.4	2.8	0.7
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.5	0.2	-0.6	0.7
Medication: Metformin	0.2	0.3	0.6	-0.2	-0.6	-0.8
Trunk fat percentage	0.2	0.9	2.0	-0.8	-1.4	-0.2
Townsend deprivation index at recruitment	0.2	0.3	0.6	-0.4	-0.2	-0.8
Taking other prescription medications	0.2	0.3	0.7	-0.3	-0.9	-0.1
High blood pressure	0.2	0.6	0.9	0.7	-0.9	0.7
Illnesses of siblings	0.2	0.3	0.5	-0.7	0.6	-0.0
Impedance of arm (right)	0.2	0.7	2.2	0.1	1.5	0.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.4	0.7	0.5	-0.4
Medication: Paracetamol	0.2	0.3	0.4	0.6	-0.4	0.5
Wheeze or whistling in the chest in last year	0.2	0.3	0.7	0.3	0.4	0.8
Shortness of breath walking on level ground	0.2	0.3	0.6	0.4	0.8	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.3	0.6	0.6	0.0
Had major operations	0.2	0.2	0.5	-0.7	-0.3	-0.3
Arm fat percentage (left)	0.2	0.6	1.5	-0.2	-1.2	-0.6
Average weekly red wine intake	0.2	0.3	0.6	0.8	-0.4	0.4
Mineral and other dietary supplements	0.2	0.2	0.4	0.7	0.5	-0.1
Medication: Gliclazide	0.2	0.2	0.5	-0.0	-0.7	0.1
Wears glasses or contact lenses	0.2	0.3	0.5	-0.3	-0.5	0.7
Irritability	0.2	0.3	0.6	0.4	0.3	-0.8
Diastolic blood pressure, automated reading	0.2	0.7	1.8	1.4	-0.1	-0.6
Bipolar Disorder or Schizophrenia	0.1	0.1	0.4	0.6	0.0	0.0
Schizophrenia (2018)	0.1	0.2	0.5	0.7	0.0	0.0
Fasting Glucose	0.1	0.1	0.2	-0.3	-0.1	-0.4
HDL Cholesterol	0.1	0.2	0.5	-0.7	-0.4	0.0
Schizophrenia (2014)	0.1	0.1	0.4	0.6	0.0	0.0
Ulcerative Colitis	0.1	0.1	0.3	-0.5	0.0	0.0
Blood Platelet Count	0.1	1.4	2.5	1.2	0.4	1.6
BMI	0.1	0.6	1.5	-0.1	-1.2	-0.5
Systolic Blood Pressure	0.1	0.5	0.9	0.9	0.6	0.5
Lung FEV1/FVC ratio	0.1	0.5	1.4	0.2	-0.2	-1.2
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.2	0.2	-0.4	-0.4
Systolic blood pressure, automated reading	0.1	0.3	0.9	0.9	-0.3	-0.3
Medication for hormone replacement therapy	0.1	0.2	0.2	-0.3	-0.4	0.4
Medication: Atenolol	0.1	0.1	0.3	0.3	0.1	-0.5
Number of incorrect matches in round	0.1	0.2	0.3	-0.5	-0.2	0.4
Arm fat percentage (right)	0.1	0.6	1.1	-0.2	-1.1	-0.7
Time employed in main current job	0.1	0.1	0.2	0.4	0.1	0.3
Father’s age at death	0.1	0.2	0.5	-0.7	-0.2	-0.3
Lung cancer (father)	0.1	0.1	0.2	0.3	0.3	0.4
Impedance of arm (left)	0.1	0.7	1.8	0.1	1.4	0.3
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.2	-0.5	-0.3	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.4	0.3	-0.2	-0.7
Body fat percentage	0.1	0.4	1.1	-0.1	-1.0	-0.2
Leg fat percentage (right)	0.1	0.3	0.8	0.9	-0.2	0.1
Age at last live birth	0.1	0.2	0.5	-0.7	-0.1	0.2
Illnesses of siblings: Diabetes	0.1	0.1	0.2	0.5	-0.0	0.2
Leg fat percentage (left)	0.1	0.2	0.6	0.8	-0.3	0.1
Bipolar Disorder (2018)	0.0	0.0	0.0	0.1	0.0	0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.1	0.4	0.0	0.0
Hypothyroidism (self reported)	0.0	0.1	0.3	0.5	0.0	-0.2
Illnesses of mother	0.0	0.1	0.1	-0.3	-0.3	0.1
Comparative body size at age 10	0.0	0.1	0.1	0.4	-0.4	0.1
Osteoarthritis (self-reported)	0.0	0.1	0.1	0.0	-0.3	-0.2

Hub : Genes

OBFC2B

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Trait associations