[Hub]/) : Traits : Trunk fat-free mass : ← →

chr1:154,282,146-155,910,830

Best TWAS P=3.43e-38 · Best GWAS P=1.38e-34 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Skin Sun Exposed Lower leg	ADAM15	0.14	0.09	lasso	4	0.08	6.1e-07	12.27	-12.9	3.4e-38	-0.96	0.00	1.00	TRUE
2	GTEx	Brain Nucleus accumbens basal ganglia	DCST2	0.28	0.04	lasso	5	0.13	2.0e-04	12.27	7.9	3.6e-15	0.69	0.02	0.90	TRUE
5	GTEx	Esophagus Mucosa	MUC1	0.17	0.20	lasso	4	0.18	5.6e-12	-7.54	-7.1	1.6e-12	-0.12	1.00	0.00	TRUE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RAG1AP1	0.07	0.00	blup	76	0.00	2.9e-01	-3.52	-6.5	8.7e-11	-0.17	0.02	0.09	TRUE
3	GTEx	Breast Mammary Tissue (Female)	FAM189B	0.05	-0.01	lasso	2	0.00	4.8e-01	-6.49	6.5	9.4e-11	0.09	0.04	0.07	TRUE
19	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ADAM15	0.09	0.00	blup	49	0.02	3.6e-02	-0.64	-5.8	4.9e-09	-0.43	0.01	0.09	TRUE
11	GTEx	Thyroid	DCST2	0.16	0.12	lasso	2	0.11	6.4e-09	-3.60	5.6	2.2e-08	0.53	0.38	0.62	TRUE
6	GTEx	Pancreas	THBS3	0.36	0.14	lasso	6	0.12	1.0e-05	2.19	-5.2	2.2e-07	-0.34	0.18	0.54	TRUE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZBTB7B	0.05	0.06	lasso	2	0.05	1.8e-06	12.27	-12.3	1.4e-34	-1.00	0.00	1.00	FALSE
1	GTEx	Brain Cerebellar Hemisphere	DCST2	0.45	0.10	lasso	6	0.16	6.6e-05	-3.60	9.0	2.5e-19	0.75	0.01	0.96	FALSE
7	GTEx	Pancreas	RP11-263K19.4	0.22	0.06	enet	23	0.05	3.1e-03	2.19	-7.6	2.3e-14	-0.43	0.06	0.49	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	SLC50A1	0.06	0.02	bslmm	331	0.03	4.3e-05	-7.54	-6.9	6.0e-12	-0.27	0.65	0.04	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	GBA	0.05	0.01	lasso	2	0.01	2.3e-02	8.00	-6.8	7.4e-12	-0.07	0.00	0.85	FALSE
12	NTR	Blood	ZBTB7B	0.02	0.02	lasso	1	0.01	5.4e-05	6.57	6.6	5.0e-11	0.67	0.87	0.03	FALSE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	ADAM15	0.15	0.02	blup	49	0.08	1.4e-05	7.48	-6.5	5.7e-11	-0.34	0.03	0.04	FALSE
10	GTEx	Testis	MUC1	0.20	0.02	lasso	7	0.07	7.5e-04	-7.62	-6.5	7.1e-11	-0.11	0.27	0.05	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MUC1	0.04	0.01	enet	4	0.02	1.3e-03	-7.54	-6.2	4.8e-10	-0.15	0.02	0.40	FALSE
4	GTEx	Esophagus Mucosa	ADAM15	0.11	0.02	enet	16	0.04	1.5e-03	-5.31	-6.0	1.8e-09	-0.43	0.13	0.78	FALSE
14	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TRIM46	0.03	0.00	blup	33	0.02	3.6e-03	-7.54	-6.0	2.3e-09	-0.11	0.03	0.17	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	GBAP1	0.15	0.06	lasso	4	0.06	3.6e-04	-7.62	5.9	3.1e-09	0.11	0.54	0.04	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIM46	0.03	0.01	blup	32	0.01	4.9e-03	-7.48	-5.2	1.8e-07	-0.11	0.01	0.14	FALSE