[Hub]/) : Traits : Peak expiratory flow (PEF) : ←

chr20:32,254,831-34,980,465

Best TWAS P=1.66e-17 · Best GWAS P=2.04e-19 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CEP250	0.02	0.00	blup	344	0.00	1.0e-01	5.0	-6.3	4.0e-10	-0.62	0.23	0.11	FALSE
2	CommonMind	Brain Pre-frontal Cortex	UQCC	0.07	0.04	lasso	2	0.05	1.4e-06	7.4	-7.6	3.1e-14	-0.88	0.15	0.85	FALSE
3	GTEx	Adipose Subcutaneous	UQCC1	0.09	0.12	lasso	2	0.11	4.5e-09	7.7	-7.7	9.5e-15	-0.90	0.94	0.06	FALSE
4	GTEx	Adipose Subcutaneous	MAP1LC3A	0.17	0.18	enet	22	0.19	2.1e-15	5.7	5.3	1.2e-07	0.24	0.03	0.97	FALSE
5	GTEx	Adipose Visceral Omentum	UQCC1	0.15	0.08	lasso	7	0.07	1.6e-04	7.7	-7.2	4.5e-13	-0.87	0.48	0.37	FALSE
6	GTEx	Adrenal Gland	MMP24-AS1	0.18	0.04	enet	10	0.13	2.2e-05	6.3	-6.7	2.4e-11	-0.74	0.22	0.21	FALSE
7	GTEx	Artery Aorta	MAP1LC3A	0.19	0.22	enet	36	0.23	4.3e-13	5.7	6.4	1.8e-10	0.29	0.05	0.95	FALSE
8	GTEx	Artery Coronary	MAP1LC3A	0.26	0.21	lasso	7	0.24	8.3e-09	-5.3	6.1	1.1e-09	0.27	0.08	0.92	FALSE
9	GTEx	Artery Tibial	TP53INP2	0.09	0.08	lasso	1	0.07	5.6e-06	5.7	5.7	9.3e-09	0.06	0.02	0.97	FALSE
10	GTEx	Artery Tibial	GSS	0.06	0.02	enet	25	0.04	7.7e-04	5.7	8.2	3.2e-16	0.35	0.29	0.08	FALSE
11	GTEx	Artery Tibial	MAP1LC3A	0.13	0.15	enet	23	0.21	2.2e-16	5.7	6.7	2.3e-11	0.27	0.04	0.96	TRUE
12	GTEx	Brain Cerebellar Hemisphere	MAP1LC3A	0.28	0.22	lasso	13	0.29	4.0e-08	-5.4	5.3	9.8e-08	0.29	0.08	0.92	FALSE
13	GTEx	Brain Cerebellar Hemisphere	CEP250	0.51	0.40	lasso	12	0.36	4.7e-10	5.4	-5.2	2.1e-07	-0.58	0.99	0.01	FALSE
14	GTEx	Brain Cerebellar Hemisphere	RP3-477O4.14	0.15	0.13	lasso	5	0.11	9.2e-04	5.4	-5.8	7.0e-09	-0.59	0.14	0.16	FALSE
15	GTEx	Brain Cerebellum	CEP250	0.39	0.16	enet	28	0.24	8.8e-08	5.6	-5.5	4.8e-08	-0.62	0.98	0.01	FALSE
16	GTEx	Brain Cerebellum	RP4-614O4.12	0.20	0.05	lasso	5	0.03	3.7e-02	5.7	-6.0	1.7e-09	-0.33	0.15	0.19	FALSE
17	GTEx	Brain Cortex	ERGIC3	0.15	-0.01	lasso	6	0.00	2.8e-01	3.0	5.5	2.9e-08	0.68	0.12	0.10	FALSE
18	GTEx	Brain Cortex	CEP250	0.14	0.16	enet	13	0.15	4.9e-05	5.7	-5.8	8.6e-09	-0.64	0.52	0.24	FALSE
19	GTEx	Brain Frontal Cortex BA9	UQCC1	0.16	0.07	lasso	3	0.08	3.7e-03	7.4	-7.1	1.2e-12	-0.80	0.08	0.38	FALSE
20	GTEx	Brain Nucleus accumbens basal ganglia	EDEM2	0.17	0.00	lasso	4	0.00	2.7e-01	4.2	-5.3	8.8e-08	-0.40	0.07	0.35	FALSE
21	GTEx	Brain Nucleus accumbens basal ganglia	CEP250	0.15	0.09	lasso	2	0.05	2.1e-02	5.4	-5.4	7.7e-08	-0.59	0.19	0.24	FALSE
22	GTEx	Breast Mammary Tissue	UQCC1	0.10	0.06	lasso	8	0.08	5.3e-05	-4.7	-7.4	1.6e-13	-0.66	0.45	0.30	FALSE
23	GTEx	Breast Mammary Tissue	MAP1LC3A	0.16	0.15	enet	19	0.14	1.8e-07	-5.3	5.8	6.6e-09	0.25	0.06	0.94	FALSE
24	GTEx	Breast Mammary Tissue (Male)	UQCC1	0.06	0.04	lasso	1	0.02	1.4e-01	7.9	-7.9	4.1e-15	-0.90	0.04	0.13	FALSE
25	GTEx	Breast Mammary Tissue (Male)	MAP1LC3A	0.13	0.05	enet	12	0.00	3.4e-01	-5.0	5.3	1.1e-07	0.22	0.05	0.33	FALSE
26	GTEx	Breast Mammary Tissue (Female)	MAP1LC3A	0.12	0.05	lasso	10	0.05	1.0e-02	5.7	5.7	1.4e-08	0.26	0.05	0.89	FALSE
27	GTEx	Cells EBV-transformed lymphocytes	PROCR	0.19	0.05	enet	25	0.09	7.3e-04	2.0	5.5	4.2e-08	0.58	0.09	0.23	FALSE
28	GTEx	Cells Transformed fibroblasts	UQCC1	0.23	0.24	lasso	8	0.25	9.4e-19	7.7	-7.6	3.4e-14	-0.88	0.98	0.02	FALSE
29	GTEx	Cells Transformed fibroblasts	MAP1LC3A	0.07	0.07	enet	19	0.06	3.4e-05	5.6	6.2	5.9e-10	0.28	0.04	0.96	FALSE
30	GTEx	Colon Sigmoid	MAP1LC3A	0.10	0.04	enet	19	0.10	3.1e-04	5.4	5.6	2.7e-08	0.23	0.08	0.90	FALSE
31	GTEx	Colon Transverse	UQCC1	0.11	0.01	lasso	4	0.01	1.0e-01	4.5	-5.5	3.2e-08	-0.48	0.08	0.09	FALSE
32	GTEx	Colon Transverse	MAP1LC3A	0.15	0.14	lasso	3	0.09	3.2e-05	5.7	5.6	2.7e-08	0.22	0.05	0.95	FALSE
33	GTEx	Esophagus Gastroesophageal Junction	MAP1LC3A	0.14	0.09	enet	9	0.07	1.4e-03	-5.3	5.9	3.4e-09	0.30	0.06	0.90	FALSE
34	GTEx	Esophagus Mucosa	UQCC1	0.13	0.10	enet	10	0.07	1.1e-05	7.9	-7.8	8.6e-15	-0.89	0.44	0.55	FALSE
35	GTEx	Esophagus Muscularis	ITCH	0.07	0.02	lasso	3	0.01	6.3e-02	4.6	-5.3	1.1e-07	-0.24	0.06	0.87	FALSE
36	GTEx	Esophagus Muscularis	MAP1LC3A	0.18	0.19	enet	28	0.23	2.3e-14	5.7	6.0	1.8e-09	0.27	0.04	0.96	FALSE
37	GTEx	Esophagus Muscularis	RP4-614O4.12	0.11	0.09	lasso	4	0.12	1.3e-07	5.2	-5.4	6.8e-08	-0.28	0.97	0.00	FALSE
38	GTEx	Heart Atrial Appendage	MAP1LC3A	0.12	0.09	enet	16	0.16	1.4e-07	4.5	5.3	9.7e-08	0.24	0.08	0.92	FALSE
39	GTEx	Heart Left Ventricle	MAP1LC3A	0.12	0.11	lasso	14	0.13	1.8e-07	-4.5	5.3	1.2e-07	0.25	0.17	0.83	FALSE
40	GTEx	Lung	UQCC1	0.13	0.08	lasso	5	0.06	1.0e-05	7.7	-7.7	1.2e-14	-0.90	0.46	0.54	FALSE
41	GTEx	Lung	MAP1LC3A	0.08	0.09	lasso	2	0.09	1.6e-07	5.7	5.7	1.4e-08	0.24	0.03	0.97	FALSE
42	GTEx	Muscle Skeletal	GSS	0.04	0.05	enet	11	0.03	2.7e-04	-5.0	5.2	1.9e-07	0.21	0.88	0.01	FALSE
43	GTEx	Muscle Skeletal	UQCC1	0.10	0.04	enet	19	0.05	1.3e-05	6.3	-6.0	1.7e-09	-0.79	0.64	0.34	FALSE
44	GTEx	Muscle Skeletal	MAP1LC3A	0.03	0.03	lasso	3	0.03	7.1e-04	5.7	5.8	7.3e-09	0.24	0.05	0.93	FALSE
45	GTEx	Muscle Skeletal	CEP250	0.09	0.04	lasso	9	0.07	3.6e-07	5.6	-6.7	2.0e-11	-0.79	0.98	0.01	FALSE
46	GTEx	Muscle Skeletal	GGT7	0.07	0.02	enet	26	0.03	7.2e-04	4.1	6.2	4.8e-10	0.28	0.93	0.00	FALSE
47	GTEx	Muscle Skeletal	ACSS2	0.04	0.04	enet	12	0.04	3.1e-05	4.7	5.7	1.1e-08	0.29	0.83	0.01	FALSE
48	GTEx	Muscle Skeletal	NFS1	0.03	0.02	lasso	3	0.03	1.0e-03	5.1	6.3	3.0e-10	0.66	0.17	0.59	FALSE
49	GTEx	Nerve Tibial	UQCC1	0.07	0.04	enet	6	0.03	2.7e-03	7.8	-7.4	1.4e-13	-0.88	0.23	0.73	TRUE
50	GTEx	Nerve Tibial	MAP1LC3A	0.19	0.24	enet	18	0.22	1.0e-15	-5.3	5.5	5.0e-08	0.25	0.11	0.89	FALSE
51	GTEx	Ovary	MAP1LC3A	0.10	0.03	lasso	5	0.08	6.3e-03	5.7	5.5	3.6e-08	0.24	0.06	0.64	FALSE
52	GTEx	Ovary	RP4-614O4.12	0.23	0.13	lasso	3	0.19	2.3e-05	-4.4	-5.4	5.5e-08	-0.33	0.14	0.14	FALSE
53	GTEx	Pancreas	MAP1LC3A	0.06	0.09	lasso	4	0.08	3.0e-04	5.4	5.7	1.4e-08	0.26	0.06	0.91	FALSE
54	GTEx	Pituitary	MAP1LC3A	0.26	0.29	enet	19	0.29	5.9e-08	5.3	5.4	7.5e-08	0.26	0.07	0.92	FALSE
55	GTEx	Prostate	MAP1LC3A	0.33	0.26	lasso	8	0.31	1.6e-08	5.7	5.6	1.7e-08	0.25	0.06	0.93	FALSE
56	GTEx	Skin Sun Exposed Lower leg	ITCH	0.04	0.04	enet	11	0.04	6.3e-04	-5.3	-5.5	2.9e-08	-0.26	0.08	0.90	FALSE
57	GTEx	Skin Sun Exposed Lower leg	UQCC1	0.19	0.13	enet	16	0.10	8.1e-09	7.8	-8.2	1.8e-16	-0.84	0.98	0.02	FALSE
58	GTEx	Skin Sun Exposed Lower leg	MAP1LC3A	0.03	0.04	lasso	3	0.04	4.7e-04	-5.0	5.3	9.5e-08	0.22	0.11	0.80	FALSE
59	GTEx	Skin Sun Exposed Lower leg	EIF6	0.40	0.21	lasso	5	0.19	1.2e-15	4.4	5.3	1.1e-07	0.48	1.00	0.00	FALSE
60	GTEx	Stomach	UQCC1	0.09	0.14	lasso	2	0.15	1.9e-07	7.7	-7.6	3.2e-14	-0.86	0.45	0.40	FALSE
61	GTEx	Stomach	MAP1LC3A	0.10	0.04	enet	10	0.05	1.3e-03	-5.3	5.9	3.2e-09	0.27	0.07	0.81	FALSE
62	GTEx	Testis	MAP1LC3A	0.42	0.38	enet	33	0.40	3.0e-19	5.3	5.9	2.9e-09	0.27	0.06	0.94	TRUE
63	GTEx	Thyroid	MAP1LC3A	0.17	0.27	enet	19	0.26	2.7e-20	5.6	5.8	8.3e-09	0.25	0.02	0.98	FALSE
64	GTEx	Whole Blood	MAP1LC3A	0.05	0.03	enet	15	0.00	1.8e-01	5.7	5.7	9.4e-09	0.27	0.04	0.93	FALSE
65	METSIM	Adipose	MAP1LC3A	0.05	0.06	blup	309	0.06	7.2e-09	5.3	6.5	5.9e-11	0.25	0.08	0.92	FALSE
66	METSIM	Adipose	RP3-477O4.16	0.07	0.08	lasso	3	0.07	1.6e-10	5.6	5.5	3.2e-08	0.63	1.00	0.00	FALSE
67	METSIM	Adipose	UQCC1	0.09	0.04	enet	18	0.05	1.5e-07	7.7	-8.0	1.2e-15	-0.90	0.14	0.86	FALSE
68	NTR	Blood	UQCC	0.01	0.01	enet	6	0.00	1.6e-02	7.7	-7.8	4.7e-15	-0.89	0.08	0.78	FALSE
69	ROSMAP	Brain Pre-frontal Cortex	UQCC1	0.05	0.05	lasso	5	0.06	1.7e-08	7.6	-7.7	1.9e-14	-0.84	0.21	0.79	FALSE
70	ROSMAP	Brain Pre-frontal Cortex	MAP1LC3A	0.33	0.51	lasso	7	0.56	1.4e-87	-5.0	5.6	2.4e-08	0.23	0.49	0.50	FALSE
71	ROSMAP	Brain Pre-frontal Cortex	GDF5	0.10	0.13	lasso	2	0.12	2.9e-15	7.7	7.7	9.6e-15	0.90	0.81	0.19	FALSE
72	ROSMAP	Brain Pre-frontal Cortex	CEP250	0.15	0.14	lasso	5	0.13	2.3e-16	5.8	-5.8	6.0e-09	-0.64	1.00	0.00	FALSE
73	ROSMAP	Brain Pre-frontal Cortex	ACSS2	0.07	0.06	blup	353	0.07	9.4e-10	-4.1	5.2	1.6e-07	0.25	1.00	0.00	FALSE
74	YFS	Blood	CEP250	0.15	0.12	lasso	13	0.13	9.2e-41	5.9	-5.9	4.8e-09	-0.63	1.00	0.00	FALSE
75	YFS	Blood	PROCR	0.01	0.00	blup	348	0.01	3.3e-03	4.8	-5.7	1.1e-08	-0.70	0.08	0.75	FALSE
76	YFS	Blood	UQCC	0.21	0.19	lasso	26	0.20	6.4e-64	7.7	-8.0	1.3e-15	-0.88	0.98	0.02	FALSE
77	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	UQCC	0.03	0.04	blup	67	0.03	2.6e-03	7.8	-8.1	6.4e-16	-0.91	0.02	0.91	FALSE
78	The Cancer Genome Atlas	Breast Invasive Carcinoma	CEP250	0.01	0.02	blup	43	0.02	5.8e-05	5.6	5.3	9.5e-08	0.59	0.89	0.01	FALSE
79	The Cancer Genome Atlas	Breast Invasive Carcinoma	GGT7	0.02	0.02	lasso	3	0.02	2.2e-04	5.7	-5.9	3.2e-09	-0.09	0.00	0.99	FALSE
80	The Cancer Genome Atlas	Breast Invasive Carcinoma	UQCC	0.08	0.11	blup	67	0.12	1.1e-22	7.9	-7.6	3.7e-14	-0.89	0.97	0.03	FALSE
81	The Cancer Genome Atlas	Colon Adenocarcinoma	ERGIC3	0.05	0.03	blup	39	0.04	3.0e-03	5.0	-5.3	1.5e-07	-0.61	0.02	0.86	FALSE
82	The Cancer Genome Atlas	Glioblastoma Multiforme	UQCC	0.15	0.02	blup	67	0.04	2.0e-02	3.0	-7.1	1.4e-12	-0.74	0.02	0.64	FALSE
83	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CEP250	0.02	0.01	blup	43	0.02	8.0e-04	5.7	7.2	6.0e-13	0.79	0.03	0.83	FALSE
84	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	UQCC	0.05	0.06	blup	66	0.06	3.6e-07	6.5	-7.4	1.7e-13	-0.87	0.13	0.87	FALSE
85	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CEP250	0.03	0.01	blup	43	0.03	2.6e-04	9.0	6.7	2.9e-11	0.77	0.01	0.89	TRUE
86	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UQCC	0.09	0.10	blup	67	0.10	7.2e-11	7.6	-7.3	2.3e-13	-0.88	0.96	0.04	FALSE
87	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	UQCC	0.08	0.01	lasso	3	0.01	9.0e-02	6.3	-6.2	6.6e-10	-0.72	0.04	0.85	FALSE
88	The Cancer Genome Atlas	Brain Lower Grade Glioma	GDF5	0.09	0.11	blup	76	0.12	1.0e-13	7.6	7.3	2.8e-13	0.83	0.14	0.86	FALSE
89	The Cancer Genome Atlas	Brain Lower Grade Glioma	MAP1LC3A	0.02	0.03	lasso	3	0.02	8.3e-04	-5.3	5.3	1.1e-07	0.26	0.02	0.95	FALSE
90	The Cancer Genome Atlas	Brain Lower Grade Glioma	UQCC	0.04	0.06	lasso	6	0.05	2.3e-06	7.8	-7.8	9.0e-15	-0.90	0.65	0.35	FALSE
91	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CEP250	0.09	0.06	lasso	4	0.06	1.2e-03	5.4	5.5	4.4e-08	0.60	0.51	0.18	TRUE
92	The Cancer Genome Atlas	Lung Adenocarcinoma	UQCC	0.10	0.07	enet	10	0.07	1.5e-08	7.6	-7.6	2.3e-14	-0.89	0.09	0.91	FALSE
93	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MMP24	0.04	0.04	blup	62	0.02	7.4e-04	4.5	-5.9	2.9e-09	-0.55	0.25	0.67	FALSE
94	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UQCC	0.07	0.08	blup	67	0.07	1.1e-08	7.6	-7.6	3.5e-14	-0.82	0.05	0.95	FALSE
95	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	GDF5	0.05	0.02	blup	76	0.04	1.4e-03	7.7	7.9	2.0e-15	0.89	0.03	0.91	FALSE
96	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	UQCC	0.12	0.03	blup	67	0.09	1.7e-04	7.4	-6.7	2.0e-11	-0.83	0.02	0.89	FALSE
97	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	UQCC	0.22	0.21	lasso	7	0.18	1.9e-07	7.4	-7.5	4.4e-14	-0.84	0.31	0.68	FALSE
98	The Cancer Genome Atlas	Prostate Adenocarcinoma	CEP250	0.08	0.15	enet	16	0.15	3.1e-15	5.9	5.6	2.0e-08	0.63	1.00	0.00	FALSE
99	The Cancer Genome Atlas	Prostate Adenocarcinoma	FAM83C	0.16	0.10	lasso	4	0.11	2.1e-11	5.6	-5.7	1.4e-08	-0.58	1.00	0.00	FALSE
100	The Cancer Genome Atlas	Prostate Adenocarcinoma	GDF5	0.05	0.05	lasso	5	0.04	7.2e-05	9.0	8.5	2.3e-17	0.95	0.00	1.00	FALSE
101	The Cancer Genome Atlas	Prostate Adenocarcinoma	GGT7	0.05	0.02	enet	6	0.03	3.3e-04	4.3	-5.7	1.1e-08	-0.19	0.01	0.96	FALSE
102	The Cancer Genome Atlas	Prostate Adenocarcinoma	UQCC	0.07	0.10	lasso	8	0.11	1.3e-11	7.6	-7.8	4.5e-15	-0.90	0.37	0.63	FALSE
103	The Cancer Genome Atlas	Soft Tissue Sarcoma	UQCC	0.07	0.06	blup	66	0.07	5.2e-05	7.7	-7.7	1.3e-14	-0.89	0.02	0.97	FALSE
104	The Cancer Genome Atlas	Stomach Adenocarcinoma	GDF5	0.09	0.04	enet	13	0.05	2.4e-04	9.0	8.5	1.7e-17	0.85	0.00	0.99	TRUE
105	The Cancer Genome Atlas	Stomach Adenocarcinoma	UQCC	0.07	0.06	lasso	10	0.06	2.8e-05	7.4	-7.4	1.0e-13	-0.88	0.04	0.95	FALSE
106	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CEP250	0.10	0.00	blup	43	0.05	9.8e-03	6.3	6.2	6.3e-10	0.73	0.01	0.24	FALSE
107	The Cancer Genome Atlas	Thyroid Carcinoma	CEP250	0.05	0.03	blup	43	0.04	5.8e-05	5.8	7.2	7.1e-13	0.78	0.12	0.83	FALSE
108	The Cancer Genome Atlas	Thyroid Carcinoma	GDF5	0.02	0.00	blup	76	0.00	1.9e-01	7.9	7.7	1.5e-14	0.90	0.02	0.88	FALSE
109	The Cancer Genome Atlas	Thyroid Carcinoma	ITCH	0.04	0.06	blup	64	0.06	8.4e-07	-5.4	5.3	1.2e-07	0.26	0.04	0.96	FALSE
110	The Cancer Genome Atlas	Thyroid Carcinoma	UQCC	0.15	0.21	blup	67	0.22	1.2e-20	7.9	-7.7	1.9e-14	-0.88	0.50	0.50	FALSE
111	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	UQCC	0.13	0.15	lasso	1	0.11	7.1e-04	5.9	-5.9	3.7e-09	-0.74	0.04	0.65	FALSE