TWAS hub - DAZAP2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0730	0.0250	6.7e-05	0.036	0.049	0.039	0.045	0.049	3.2e-05	1.2e-06	1.4e-05	2.9e-06	1.1e-06
2	METSIM	Adipose	0.0588	0.0247	4.8e-03	0.054	0.015	0.044	0.041	0.046	1.7e-08	1.8e-03	2.7e-07	8.8e-07	1.8e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Supplements: Calcium	6.0	6.7	7.1	-2.7	-2.5
Blood Platelet Count	5.8	66.7	132.2	11.5	-1.1
Medication: Lansoprazole	5.2	5.9	11.8	0.2	3.4
Bipolar Disorder (2018)	4.9	7.7	11.4	2.0	3.4
Hair/balding pattern: Pattern 3	4.6	6.8	13.5	-0.2	-3.7
Bipolar Disorder (2011)	4.5	4.3	8.1	0.7	2.9
Eye problems/disorders: None of the above	3.5	4.0	6.5	-1.2	2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.5	4.2	7.7	2.8	-0.8
Breast cancer (self-reported)	3.2	3.8	5.0	-1.6	-2.2
Commuting to job workplace: Walk	2.9	3.1	4.8	-1.2	2.2
Pain experienced in last month	2.9	4.9	5.3	2.3	2.1
Number of incorrect matches in round	2.8	4.6	9.1	0.4	-3.0
Worry too long after embarrassment	2.8	4.7	5.7	-2.4	-1.9
Ever highly irritable/argumentative for 2 days	2.7	3.3	4.6	2.1	1.4
Medication: Ventolin 100micrograms inhaler	2.7	3.4	5.6	1.1	2.4
Neuroticism (2016)	2.5	3.6	6.9	-2.6	0.6
Deep venous thrombosis (DVT) (self-reported)	2.5	3.2	4.3	2.1	1.5
Ever used hormone-replacement therapy (HRT)	2.4	3.1	4.7	2.2	1.2
Falls in the last year	2.4	3.2	6.1	-2.5	-0.5
Blood clot in the leg (DVT)	2.4	3.2	3.9	2.0	1.6
Had major operations	2.4	2.8	3.8	1.3	1.9
Osteoporosis (self-reported)	2.4	2.9	4.8	-2.2	-1.1
Eye problems/disorders: Diabetes related eye disease	2.3	2.5	3.7	1.9	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.6	7.1	0.2	2.7
Basal cell carcinoma (self-reported)	2.3	2.7	4.6	0.9	2.1
Schizophrenia vs Biploar Disorder	2.2	2.9	5.6	-0.4	-2.4
Commuting to job workplace: Cycle	2.2	2.7	4.3	-1.0	-2.1
Ever had hysterectomy (womb removed)	2.1	2.4	4.5	-2.1	-0.6
Pulse wave reflection index	2.1	2.5	4.1	-2.0	-1.0
Medication: Co-codamol	2.0	2.3	3.6	1.9	1.0
Allergy or Eczema	1.9	4.9	9.9	-3.1	-0.2
Number of children fathered	1.9	2.2	4.3	2.1	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.3	4.6	-2.1	0.1
Rheumatoid Arthritis	1.8	2.4	4.4	-0.7	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	4.4	2.1	0.5
High blood pressure	1.7	4.8	5.2	-2.1	2.3
Forced vital capacity (FVC)	1.7	6.6	8.3	-2.2	-2.9
Pain all over the body in last month	1.7	1.8	3.4	1.8	0.5
Mouth/teeth dental problems: Loose teeth	1.7	2.0	3.9	2.0	-0.3
Medication: Paracetamol	1.7	2.7	4.9	-2.2	0.7
Major Depression (MDD)	1.6	1.9	3.5	-1.9	-0.6
Chronotype (morning person)	1.6	3.8	7.4	0.3	2.7
Frequency of depressed mood in last 2 weeks	1.6	2.2	2.3	1.4	1.5
Systolic blood pressure, automated reading	1.6	4.6	6.6	-2.6	-1.6
Chronic bronchitis/emphysema (father)	1.6	1.9	3.6	0.4	1.9
Bipolar Disorder or Schizophrenia	1.5	3.7	4.5	2.1	1.7
Bilateral oophorectomy (both ovaries removed)	1.5	1.8	3.4	0.4	1.9
Qualifications: CSEs or equivalent	1.5	2.0	2.9	1.7	1.1
Mean time to correctly identify matches	1.5	2.9	5.5	0.5	-2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.3	6.6	-2.6	0.0
Pack years of smoking	1.5	2.3	3.0	-1.2	-1.7
Ulcerative Colitis (UC)	1.4	2.7	3.2	1.8	1.5
Cardiovascular Disease	1.4	4.6	6.5	-1.6	2.6
Medication: Ramipril	1.4	1.9	2.7	1.0	1.7
Happiness	1.4	1.7	2.1	1.2	-1.4
Lung cancer (father)	1.4	1.7	2.6	1.6	0.9
Standing height	1.4	13.9	27.7	0.5	-5.3
Length of working week for main job	1.4	1.5	3.0	1.7	-0.2
Comparative height size at age 10	1.4	8.0	15.8	-0.2	-4.0
Handedness (chirality/laterality): Left-handed	1.4	1.6	2.4	0.9	1.5
Medication for cholesterol	1.4	2.1	4.1	-0.3	-2.0
Commuting to job workplace: Public transport	1.4	1.6	2.4	-0.9	-1.6
Risk taking	1.4	2.1	3.3	1.8	-0.9
Age started oral contraceptive pill	1.4	1.8	2.5	-1.1	-1.6
Vascular/heart problems diagnosed by doctor	1.4	3.8	4.1	1.9	-2.0
Lung FVC	1.3	6.5	11.0	-3.3	-1.4
Age when periods started (menarche)	1.3	3.1	5.6	0.8	-2.4
Noisy workplace	1.3	1.6	3.0	0.4	1.7
Headache pain in last month	1.3	2.2	4.2	-2.1	-0.4
Smoking status: Current	1.3	2.1	2.5	-1.3	-1.6
Wears glasses or contact lenses	1.3	1.5	2.8	1.7	-0.4
Pain type(s) experienced in last month: Hip pain	1.3	1.6	2.8	-0.7	-1.7
Age at First Birth	1.2	1.8	2.8	0.9	1.7
BMI	1.2	7.0	13.4	0.8	3.7
Pack years adult smoking proportion	1.2	1.8	2.2	-1.2	-1.5
Hayfever, allergic rhinitis or eczema	1.2	2.5	4.7	-2.2	-0.7
Had other major operations	1.2	1.5	2.8	-1.7	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.7	6.3	-2.5	-1.0
Exposure to tobacco smoke at home	1.2	1.4	2.6	-0.4	-1.6
Forced vital capacity (FVC), Best measure	1.2	4.6	7.1	-2.7	-1.4
Average weekly beer plus cider intake	1.2	1.8	3.2	1.8	0.6
Alzheimer’s Disease (in mother)	1.1	1.3	2.1	-1.5	0.6
Alzheimer’s Disease (including proxy)	1.1	1.5	2.6	-1.6	0.7
Ulcerative Colitis	1.1	1.6	2.9	0.6	1.7
Hearing difficulty/problems: Yes	1.1	1.7	3.3	-1.8	-0.3
Hair/balding pattern: Pattern 2	1.1	1.4	1.7	1.0	1.3
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	4.4	-2.1	-1.8
Qualifications: College or University degree	1.1	3.4	6.7	-2.6	0.1
Medication: Seretide 50 evohaler	1.1	1.2	1.4	-1.0	-1.2
Hypertension (Self-reported)	1.1	3.1	4.1	-2.0	1.5
HDL Cholesterol	1.0	1.7	3.4	-0.3	-1.8
Severe depression (siblings)	1.0	1.1	2.1	1.5	0.3
Body mass index (BMI)	1.0	4.1	7.4	1.0	2.7
Nervous feelings	1.0	1.8	3.3	-0.5	1.8
Gout (self-reported)	1.0	1.4	2.8	-0.0	-1.7
Eye problems/disorders: Glaucoma	1.0	1.2	1.7	-0.8	-1.3
Ever had prostate specific antigen (PSA) test	1.0	1.2	1.8	1.3	0.7
Reaction Time	0.9	1.7	2.9	0.7	-1.7
Height	0.9	17.1	33.9	0.5	-5.8
Medication for hormone replacement therapy	0.9	1.0	1.6	0.7	1.2
Taking other prescription medications	0.9	1.3	1.6	-1.1	-1.2
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	1.3	0.7	1.1
High blood pressure (mother)	0.9	1.3	2.5	0.1	1.6
Waist circumference	0.9	3.5	5.4	2.3	1.2
Had menopause	0.9	1.1	2.0	0.5	-1.4
Pulse rate	0.9	1.5	1.6	1.2	1.3
Asthma	0.9	1.7	2.1	-1.2	1.4
Body fat percentage	0.9	3.6	4.2	1.7	2.1
Leg fat percentage (right)	0.9	3.2	4.7	1.3	2.2
Medication: Allopurinol	0.9	1.2	1.8	0.8	-1.3
Arm fat percentage (left)	0.9	3.6	6.2	1.0	2.5
Osteoarthritis (self-reported)	0.9	1.2	2.3	1.5	-0.4
Mother’s age at death	0.9	1.1	2.1	-1.5	-0.1
Leg fat percentage (left)	0.9	3.2	3.8	1.6	1.9
Irritability	0.9	1.5	2.3	-0.8	-1.5
Diastolic blood pressure, automated reading	0.9	2.7	4.5	-2.1	-1.0
Depression (Nagel 2018)	0.8	1.2	2.0	1.4	0.7
Body Mass Index (BMI) (2010)	0.8	1.2	1.8	0.7	1.3
LDL Cholesterol	0.8	1.2	2.3	-0.3	-1.5
Primary Biliary Cirrhosis	0.8	1.1	2.1	0.3	1.5
Waist Hip Ratio (WHR)	0.8	3.7	4.0	2.0	1.8
Hand grip strength (left)	0.8	2.0	3.4	-1.9	-0.8
Diabetes (father)	0.8	0.9	1.7	-1.3	0.4
Current tobacco smoking	0.8	1.3	1.4	-1.1	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	2.3	-1.5	-1.2
Arm fat percentage (right)	0.8	3.2	5.8	0.7	2.4
Depression (self-reported)	0.8	0.9	1.8	-1.3	0.2
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	1.6	1.3	0.9
Glaucoma (self-reported)	0.8	0.9	1.1	-0.9	-1.0
Birth weight	0.8	1.7	2.5	0.9	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	1.1	-1.0	1.0
Friendships satisfaction	0.8	1.0	1.6	-0.6	-1.3
Tinnitus: Yes, now most or all of the time	0.8	0.9	1.6	-1.3	-0.4
Schizophrenia (2014)	0.7	1.6	2.9	1.7	-0.6
Respiratory disease	0.7	1.5	2.3	-0.8	1.5
Neuroticism	0.7	1.8	3.5	-1.9	0.2
Vitamin and mineral supplements	0.7	1.0	1.1	-1.1	0.9
Trunk fat percentage	0.7	2.8	3.3	1.5	1.8
Multivitamins +/- minerals	0.7	0.9	1.7	0.2	-1.3
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	1.0	-0.8	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.6	1.3	0.2
Number of full brothers	0.7	0.8	1.7	0.0	1.3
Whole body fat mass	0.7	2.8	3.6	1.9	1.4
Mood swings	0.7	1.3	2.1	-1.4	-0.7
Asthma (self-reported)	0.7	1.5	1.6	-1.3	1.1
Miserableness	0.7	1.2	1.6	-0.9	-1.2
Illnesses of father: High blood pressure	0.7	0.9	1.7	-1.3	0.2
Ever smoked	0.7	1.2	2.2	0.3	-1.5
Fractured/broken bones in last 5 years	0.7	0.9	1.5	1.2	0.4
Heart disease (siblings)	0.7	0.8	1.5	0.3	-1.2
Neuroticism (Nagel 2018)	0.6	1.5	2.9	-1.7	-0.2
HbA1C	0.6	0.6	1.2	0.1	-1.1
Heel T-Score	0.6	4.5	5.0	-2.0	-2.2
Systolic Blood Pressure	0.6	3.1	5.2	-2.3	-1.0
Past tobacco smoking	0.6	1.1	2.0	-0.5	1.4
Hearing difficulty/problems with background noise	0.6	0.9	1.5	-1.2	-0.5
Heart attack	0.6	0.7	1.4	1.2	0.1
Alcohol intake versus 10 years previously	0.6	0.9	1.8	0.0	1.4
Worrier / anxious feelings	0.6	1.0	1.3	1.1	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	0.9	0.9	0.8
Medication: Paracetamol	0.6	0.9	1.5	-1.2	0.6
Leg fat mass (right)	0.6	2.4	2.5	1.5	1.6
Qualifications: nursing, teaching	0.6	0.9	1.5	-1.2	0.5
Back pain experienced in last month	0.6	0.9	1.8	-0.3	-1.3
Guilty feelings	0.6	0.9	1.2	-0.8	1.1
Medication: Blood pressure	0.6	1.1	1.6	-1.3	0.8
Leg fat mass (left)	0.6	2.4	3.0	1.7	1.4
Depressed Affect (Nagel 2018)	0.5	1.1	1.7	-1.3	-0.7
Irritable Bowel Disease (IBD)	0.5	1.2	2.1	1.4	0.6
Ovarian Cancer	0.5	0.7	1.0	-0.6	1.0
Blood Eosinophil Count	0.5	3.9	5.2	2.3	1.6
Average weekly fortified wine intake	0.5	0.6	0.7	0.7	0.8
Trunk fat mass	0.5	2.4	2.8	1.7	1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	1.7	-0.6	-1.3
Allergy	0.5	1.2	2.1	1.4	-0.6
Father’s age at death	0.5	0.7	1.0	0.6	1.0
Pulse wave Arterial Stiffness index	0.5	0.6	1.1	-0.2	-1.1
Tense / ‘highly strung’	0.5	0.8	1.2	0.6	-1.1
Medication: Amlodipine	0.5	0.7	1.2	0.3	1.1
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.2	-1.1	-0.2
Migraine (self-reported)	0.5	0.6	1.2	-0.3	-1.1
Leg pain on walking	0.5	0.7	1.1	-1.1	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.1	-0.4	-1.0
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.1	-1.0	-0.4
Long-standing illness, disability or infirmity	0.5	0.8	1.6	-0.1	1.3
Medication: Bendroflumethiazide	0.5	0.7	1.3	-1.2	0.3
Medication: Lisinopril	0.5	0.7	0.7	0.8	0.8
Ever depressed for a whole week	0.5	0.6	1.0	-1.0	0.4
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.1	1.1	0.2
Schizophrenia (2018)	0.4	0.8	1.3	1.1	-0.5
Lupus	0.4	0.5	1.0	-0.3	-1.0
Smoking Status	0.4	0.8	1.6	0.2	-1.3
Sensitivity / hurt feelings	0.4	0.6	1.1	-1.0	0.4
Relative age of first facial hair	0.4	0.9	1.7	-1.3	-0.0
Hand grip strength (right)	0.4	1.1	1.3	-1.2	-1.0
Serious illness, injury or assault to yourself	0.4	0.4	0.5	0.7	-0.7
Supplements: Glucosamine	0.4	0.5	1.1	-0.1	-1.0
Impedance of leg (left)	0.4	2.1	3.8	0.7	-1.9
Financial difficulties in last 2 years	0.4	0.5	1.0	-0.1	-1.0
Diabetes (self-reported)	0.4	0.6	0.7	0.8	0.8
Hip circumference	0.4	1.6	3.1	1.8	-0.1
Illnesses of mother	0.4	0.5	0.7	-0.5	-0.8
Arm fat mass (right)	0.4	1.5	2.1	1.0	1.4
Breastfed as a baby	0.4	0.5	1.0	1.0	-0.2
Peak expiratory flow (PEF)	0.4	1.0	1.3	-1.1	-0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.0	-1.0	-0.5
High blood pressure (siblings)	0.4	0.5	1.0	-1.0	-0.1
Emphysema/chronic bronchitis	0.4	0.5	0.9	0.1	-0.9
Neck or shoulder pain in last month	0.4	0.5	1.1	-1.0	-0.0
Medication: Blood pressure	0.4	0.7	1.3	0.4	1.1
Medication: Ibuprofen	0.4	0.5	1.0	0.1	1.0
Overall health rating	0.4	0.8	1.4	1.2	0.3
Family relationship satisfaction	0.4	0.4	0.8	-0.3	-0.9
Knee pain experienced in last month	0.4	0.7	1.3	-0.3	-1.1
Eye problems/disorders: Cataract	0.4	0.5	0.8	-0.3	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	0.9	-0.4	-1.0
Arm fat mass (left)	0.4	1.7	1.9	1.2	1.4
Hearing aid user	0.4	0.4	0.8	-0.9	0.1
Alcohol drinker status: Never	0.4	0.5	0.9	-0.9	0.2
Cholesterol lowering medication	0.4	0.6	1.1	-1.0	-0.3
Impedance of whole body	0.4	1.8	3.6	0.2	-1.9
Worry (Nagel 2018)	0.3	0.5	1.1	-0.0	1.0
Crohns Disease (2017)	0.3	0.7	0.8	0.8	-0.9
Fasting Glucose	0.3	0.3	0.4	-0.5	0.6
Triglycerides	0.3	0.5	0.6	0.8	0.6
Blood White Count	0.3	2.5	4.5	2.1	0.7
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.1	-0.4	1.1
Number of treatments/medications taken	0.3	0.5	0.6	-0.8	0.7
Impedance of leg (right)	0.3	1.3	2.6	0.2	-1.6
Maternal smoking around birth	0.3	0.4	0.8	0.2	-0.9
Fed-up feelings	0.3	0.6	1.1	-0.0	1.1
Medication: Levothyroxine sodium	0.3	0.5	0.5	-0.7	-0.7
Sitting height	0.3	2.3	3.9	-0.8	-2.0
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.6	0.8	0.5
Qualifications: None of the above	0.3	0.6	1.0	0.4	-1.0
Time employed in main current job	0.3	0.3	0.6	0.3	-0.7
Qualifications: A levels/AS levels or equivalent	0.3	0.6	0.9	-0.5	-0.9
Prospective memory result	0.3	0.3	0.5	-0.7	0.4
Loud music exposure frequency	0.3	0.3	0.5	0.7	0.4
Shortness of breath walking on level ground	0.3	0.4	0.8	-0.2	0.9
Medication: Omeprazole	0.3	0.4	0.7	-0.9	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.6	0.3	0.8
Smoking status: Previous	0.3	0.4	0.8	0.9	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.4	-0.6	-0.5
Mineral and other dietary supplements	0.3	0.4	0.6	0.7	0.6
Financial situation satisfaction	0.3	0.3	0.6	-0.8	-0.1
Intelligence (Savage-Jansen 2018)	0.2	0.5	0.8	-0.9	0.5
Verbal and Numeric Reasoning (VNR)	0.2	0.5	0.5	-0.7	0.7
Coronary Artery Disease (CAD)	0.2	0.3	0.3	0.6	0.5
Mean Putamen Volume	0.2	0.2	0.4	-0.6	0.3
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.4	-0.4	0.6
Angina	0.2	0.2	0.3	0.4	0.6
Supplements: Zinc	0.2	0.3	0.5	-0.7	-0.1
Townsend deprivation index at recruitment	0.2	0.3	0.5	-0.1	-0.7
Medication: Atenolol	0.2	0.3	0.5	0.2	0.7
Mouth/teeth dental problems	0.2	0.3	0.5	-0.7	0.3
Medication: Simvastatin	0.2	0.3	0.7	0.8	-0.2
Neuroticism score	0.2	0.3	0.6	-0.8	-0.3
Weight	0.2	0.8	1.6	1.2	0.2
Impedance of arm (right)	0.2	1.0	1.6	-0.6	-1.3
Trunk fat-free mass	0.2	1.3	2.2	0.6	-1.5
Medication: Cholesterol lowering	0.2	0.3	0.5	0.7	0.2
Impedance of arm (left)	0.2	1.0	1.8	-0.4	-1.3
Trunk predicted mass	0.2	1.2	2.1	0.6	-1.4
Birth weight of first child	0.2	0.4	0.7	-0.5	-0.8
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.8	-0.9	-0.3
Arm fat-free mass (right)	0.2	1.0	1.5	1.2	-0.7
Comparative body size at age 10	0.2	0.6	1.1	-0.0	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.4	-0.6	0.0
Age at first live birth	0.2	0.3	0.4	0.6	-0.4
Health satisfaction	0.2	0.2	0.5	-0.7	-0.0
Arm predicted mass (right)	0.2	0.9	1.4	1.2	-0.6
Number of full sisters	0.2	0.2	0.4	-0.7	0.0
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.4	0.2	0.6
Supplements: Vitamin C	0.2	0.3	0.4	0.6	-0.4
Diabetes diagnosed by doctor	0.2	0.3	0.4	0.5	0.6
Illnesses of father: None of the above (group 1)	0.2	0.3	0.4	0.4	-0.6
Average weekly champagne plus white wine intake	0.2	0.3	0.4	0.6	-0.5
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.6	-0.2	0.7
High cholesterol (Self-reported)	0.2	0.4	0.5	0.5	0.7
Arm fat-free mass (left)	0.2	1.2	1.5	1.2	-1.0
Number of operations (self-reported)	0.2	0.3	0.6	-0.8	0.2
Arm predicted mass (left)	0.2	0.9	1.0	1.0	-0.8
Alzheimer’s Disease (in father)	0.1	0.1	0.2	-0.1	-0.4
Crohns Disease (2012)	0.1	0.2	0.2	-0.3	0.4
Blood Red Count	0.1	0.7	1.4	-1.2	-0.1
Lung FEV1/FVC ratio	0.1	0.3	0.7	-0.8	0.0
Tanning	0.1	1.5	2.0	1.0	1.4
Average weekly spirits intake	0.1	0.1	0.2	0.3	0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.1	-0.3	-0.2
Relative age voice broke	0.1	0.1	0.2	-0.4	-0.3
Stomach or abdominal pain in last month	0.1	0.1	0.2	0.0	0.4
Alcohol usually taken with meals	0.1	0.1	0.2	0.2	0.4
Fluid intelligence score	0.1	0.2	0.4	-0.6	-0.1
Number of live births	0.1	0.2	0.3	-0.5	-0.3
Hair/balding pattern: Pattern 4	0.1	0.3	0.5	-0.2	0.7
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.3	0.1	0.5
Wheeze or whistling in the chest in last year	0.1	0.2	0.3	0.6	0.2
Pulse wave peak to peak time	0.1	0.1	0.2	0.3	0.4
Angina (self-reported)	0.1	0.1	0.2	-0.1	0.4
Heart disease (mother)	0.1	0.1	0.2	0.5	-0.2
Alcohol intake frequency.	0.1	0.2	0.4	-0.6	0.1
Suffer from ‘nerves’	0.1	0.2	0.4	0.0	0.6
Chest pain or discomfort	0.1	0.1	0.2	0.4	-0.0
Age at last live birth	0.1	0.2	0.3	-0.2	-0.6
Illnesses of father: Heart disease	0.1	0.1	0.2	0.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.3	0.1	-0.5
Whole body fat-free mass	0.1	0.8	1.1	0.7	-1.0
Loneliness, isolation	0.1	0.2	0.3	0.6	-0.1
Ever had bowel cancer screening	0.1	0.1	0.1	0.4	0.0
Medication: Aspirin	0.1	0.1	0.2	-0.5	0.2
Whole body water mass	0.1	0.7	1.0	0.7	-1.0
Leg predicted mass (right)	0.1	0.3	0.3	0.6	-0.6
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.2	-0.4
Basal metabolic rate	0.1	0.6	0.6	0.8	-0.7
Unable to work because of sickness or disability	0.1	0.1	0.1	-0.4	0.3
Alcohol drinker status: Previous	0.1	0.1	0.3	-0.5	-0.1
Breast Cancer	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Hypothyroidism (self reported)	0.0	0.1	0.1	-0.4	-0.0
Hair Pigment	0.0	0.2	0.4	0.6	-0.3
Medication: Metformin	0.0	0.0	0.0	0.2	-0.0
Diabetes (mother)	0.0	0.0	0.1	0.2	0.2
Leg fat-free mass (left)	0.0	0.2	0.3	0.5	-0.2
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.1	0.1	-0.2
Leg predicted mass (left)	0.0	0.1	0.3	0.5	-0.1
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.1	0.0	-0.3
Illnesses of siblings	0.0	0.0	0.0	0.0	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.1	0.1	0.3	-0.2
Mouth/teeth dental problems: Dentures	0.0	0.1	0.1	0.4	-0.0
Exposure to tobacco smoke outside home	0.0	0.0	0.1	0.1	-0.2
Medication for pain relief, constipation, heartburn	0.0	0.1	0.1	0.2	-0.2
Pulse rate, automated reading	0.0	0.1	0.1	-0.4	0.4
Medication: Aspirin	0.0	0.1	0.1	-0.3	0.0
Illnesses of siblings: Diabetes	0.0	0.0	0.0	0.0	0.1
Leg fat-free mass (right)	0.0	0.3	0.3	0.6	-0.5
Average weekly red wine intake	0.0	0.1	0.1	-0.3	-0.1
Medication: Gliclazide	0.0	0.0	0.0	-0.2	0.2
Number of self-reported non-cancer illnesses	0.0	0.0	0.1	-0.3	0.2
Medication: Atorvastatin	0.0	0.0	0.0	-0.0	-0.1
Myopia	0.0	0.0	0.0	0.0	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.0	-0.2	-0.1

Hub : Genes

DAZAP2

Models

Trait associations