[Hub]/) : Traits : Hayfever, allergic rhinitis or eczema : ← →

chr5:130,830,617-132,900,729

Best TWAS P=2.53e-10 · Best GWAS P=6.28e-11 conditioned to 0.586

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
37	NTR	Blood	IRF1	0.03	0.02	blup	424	0.01	5.7e-05	5.5	-6.3	2.5e-10	0.66	0.52	0.47	TRUE
9	GTEx	Cells EBV-transformed lymphocytes	SLC22A5	0.37	0.05	lasso	13	0.10	2.8e-04	-5.9	6.1	8.2e-10	-0.66	0.21	0.58	TRUE
3	GTEx	Artery Aorta	KIF3A	0.13	0.07	enet	7	0.07	6.3e-05	4.9	-5.5	4.5e-08	0.24	0.81	0.13	TRUE
22	GTEx	Skin Not Sun Exposed Suprapubic	SLC22A4	0.13	0.00	lasso	4	0.01	7.1e-02	6.0	6.0	1.7e-09	-0.63	0.14	0.17	FALSE
32	GTEx	Whole Blood	SLC22A5	0.09	0.12	lasso	2	0.10	1.7e-09	-5.9	5.9	4.5e-09	-0.73	0.12	0.88	FALSE
36	METSIM	Adipose	SLC22A5	0.05	0.08	lasso	1	0.08	1.0e-11	-5.9	5.9	4.6e-09	-0.73	0.21	0.79	FALSE
6	GTEx	Artery Tibial	KIF3A	0.11	0.08	lasso	5	0.09	3.2e-07	5.2	-5.8	6.2e-09	0.26	0.85	0.13	FALSE
7	GTEx	Artery Tibial	SLC22A5	0.18	0.12	enet	8	0.12	2.5e-09	-5.5	5.8	6.2e-09	-0.72	0.26	0.74	FALSE
42	The Cancer Genome Atlas	Thyroid Carcinoma	C5orf56	0.06	0.04	blup	98	0.03	1.3e-03	5.3	-5.7	1.0e-08	0.59	0.36	0.60	FALSE
14	GTEx	Esophagus Mucosa	SLC22A5	0.16	0.16	enet	8	0.16	6.3e-11	-5.9	5.7	1.1e-08	-0.73	0.23	0.77	FALSE
28	GTEx	Testis	P4HA2	0.14	0.13	lasso	5	0.11	1.4e-05	-5.2	-5.7	1.1e-08	0.73	0.48	0.50	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	UQCRQ	0.21	0.01	enet	30	0.04	2.0e-02	5.2	5.6	1.7e-08	-0.41	0.07	0.31	FALSE
27	GTEx	Spleen	SLC22A5	0.26	0.28	lasso	4	0.28	6.6e-08	-5.9	-5.6	2.4e-08	0.69	0.07	0.83	FALSE
19	GTEx	Ovary	PDLIM4	0.25	0.22	enet	10	0.05	2.1e-02	3.6	-5.6	2.6e-08	0.54	0.31	0.30	FALSE
16	GTEx	Lung	SLC22A5	0.10	0.15	enet	11	0.13	3.4e-10	-5.9	5.5	2.8e-08	-0.74	0.22	0.78	FALSE
24	GTEx	Skin Sun Exposed Lower leg	KIF3A	0.11	0.04	lasso	4	0.04	6.2e-04	5.3	-5.5	2.8e-08	0.24	0.57	0.11	FALSE
26	GTEx	Skin Sun Exposed Lower leg	SLC22A5	0.25	0.21	lasso	3	0.20	1.4e-16	-5.5	5.5	2.9e-08	-0.72	0.27	0.73	FALSE
34	GTEx	Whole Blood	AC116366.6	0.05	0.04	lasso	17	0.03	5.7e-04	5.5	-5.5	3.6e-08	0.63	0.17	0.71	FALSE
1	GTEx	Adipose Subcutaneous	KIF3A	0.08	0.07	lasso	3	0.07	1.2e-06	5.3	-5.5	3.9e-08	0.25	0.78	0.18	FALSE
31	GTEx	Whole Blood	SLC22A4	0.07	0.05	enet	16	0.05	4.6e-05	4.4	5.5	4.2e-08	-0.62	0.45	0.26	FALSE
40	The Cancer Genome Atlas	Brain Lower Grade Glioma	C5orf56	0.03	0.01	blup	98	0.02	4.2e-03	5.3	-5.5	5.0e-08	0.71	0.10	0.38	FALSE
12	GTEx	Cells Transformed fibroblasts	SLC22A5	0.32	0.28	lasso	7	0.35	1.6e-27	4.4	5.4	6.7e-08	-0.68	0.74	0.26	FALSE
17	GTEx	Lung	AC004041.2	0.13	0.08	lasso	9	0.08	8.8e-07	5.5	5.3	9.6e-08	-0.51	0.56	0.42	FALSE
11	GTEx	Cells Transformed fibroblasts	SEPT8	0.15	0.12	lasso	4	0.11	6.9e-09	5.1	-5.3	1.1e-07	0.22	0.87	0.12	FALSE
25	GTEx	Skin Sun Exposed Lower leg	SEPT8	0.46	0.35	lasso	6	0.33	3.2e-28	5.1	5.3	1.1e-07	-0.21	0.89	0.11	FALSE
35	METSIM	Adipose	SLC22A4	0.05	0.02	lasso	3	0.03	8.4e-06	-3.8	5.3	1.1e-07	-0.66	0.62	0.35	FALSE
29	GTEx	Thyroid	PDLIM4	0.05	0.02	enet	5	0.01	3.1e-02	-3.7	5.3	1.2e-07	-0.64	0.16	0.66	FALSE
41	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC22A4	0.09	0.07	blup	108	0.09	3.0e-09	4.0	5.3	1.2e-07	-0.62	0.07	0.93	FALSE
43	The Cancer Genome Atlas	Thyroid Carcinoma	IRF1	0.05	0.02	blup	83	0.03	1.5e-03	-5.7	-5.3	1.2e-07	0.76	0.02	0.74	FALSE
5	GTEx	Artery Tibial	P4HA2	0.12	0.15	lasso	6	0.14	3.2e-11	-5.0	-5.3	1.3e-07	0.67	0.90	0.10	FALSE
33	GTEx	Whole Blood	AC034220.3	0.08	0.05	enet	31	0.06	4.0e-06	-5.4	5.3	1.3e-07	-0.68	0.50	0.48	FALSE
10	GTEx	Cells Transformed fibroblasts	KIF3A	0.15	0.16	enet	7	0.15	2.6e-11	4.8	-5.3	1.4e-07	0.23	0.96	0.04	FALSE
21	GTEx	Skin Not Sun Exposed Suprapubic	SEPT8	0.15	0.17	lasso	2	0.17	1.4e-09	4.8	5.3	1.4e-07	-0.23	0.93	0.06	FALSE
30	GTEx	Thyroid	SLC22A5	0.17	0.07	lasso	5	0.13	4.8e-10	2.5	5.2	1.6e-07	-0.58	0.47	0.51	FALSE
15	GTEx	Esophagus Muscularis	KIF3A	0.31	0.17	lasso	5	0.20	2.2e-12	4.8	-5.2	1.7e-07	0.23	0.93	0.07	FALSE
8	GTEx	Brain Hippocampus	AC034220.3	0.21	0.15	lasso	14	0.18	5.8e-05	4.3	-5.2	1.9e-07	0.66	0.43	0.21	FALSE
44	The Cancer Genome Atlas	Thyroid Carcinoma	P4HA2	0.21	0.35	enet	10	0.35	4.7e-35	-5.1	-5.2	1.9e-07	0.67	0.00	0.99	FALSE
39	The Cancer Genome Atlas	Colon Adenocarcinoma	SLC22A5	0.08	0.04	blup	92	0.07	1.2e-04	4.4	5.2	2.3e-07	-0.65	0.03	0.91	FALSE
2	GTEx	Artery Aorta	P4HA2	0.12	0.14	lasso	2	0.11	1.2e-06	-5.2	-5.2	2.4e-07	0.66	0.85	0.12	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	PDLIM4	0.13	0.08	lasso	2	0.06	2.6e-04	-5.9	5.2	2.5e-07	-0.68	0.31	0.47	FALSE
18	GTEx	Nerve Tibial	KIF3A	0.23	0.17	lasso	5	0.15	5.3e-11	4.8	-5.1	2.8e-07	0.24	0.97	0.03	FALSE
4	GTEx	Artery Aorta	P4HA2-AS1	0.08	0.03	lasso	3	0.01	6.6e-02	-5.1	-5.1	2.9e-07	0.67	0.40	0.19	FALSE
38	YFS	Blood	SLC22A5	0.38	0.36	bslmm	430	0.37	3.0e-128	-5.9	5.1	2.9e-07	-0.67	0.12	0.88	FALSE
23	GTEx	Skin Sun Exposed Lower leg	PDLIM4	0.09	0.08	lasso	8	0.09	1.0e-07	-5.2	5.1	3.0e-07	-0.71	0.44	0.56	FALSE