TWAS hub - HSPB2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Head and Neck Squamous Cell Carcinoma	0.0262	0.0161	0.00120	0.027	0.019	0.021	NA	0.021	0.00042	0.00260	0.00190	NA	0.0016
2	TCGA	Lung Adenocarcinoma	0.0342	0.0202	0.00058	0.013	0.029	0.027	NA	0.019	0.01000	0.00023	0.00039	NA	0.0025

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Waist Hip Ratio (WHR)	13.7	61.5	104.0	10.2	4.3
Medication for cholesterol, blood pressure or diabetes	11.7	19.4	26.6	-3.5	-5.2
Wheeze or whistling in the chest in last year	10.0	17.8	26.4	-3.0	-5.1
Asthma	9.0	17.8	24.3	-3.4	-4.9
Allergy	8.8	20.2	28.9	3.4	5.4
Birth weight	8.7	18.8	29.8	-2.8	-5.5
Medication: Blood pressure	8.7	15.3	24.6	2.4	5.0
Asthma (self-reported)	8.5	16.8	21.7	-3.5	-4.7
Wears glasses or contact lenses	7.3	8.4	9.1	3.0	2.8
Illnesses of father: Heart disease	7.0	9.7	10.3	3.2	3.0
Osteoarthritis (self-reported)	7.0	9.0	11.8	-2.5	-3.4
Cardiovascular Disease	6.8	22.5	30.5	3.8	5.5
Shortness of breath walking on level ground	6.8	8.1	9.8	-3.1	-2.5
Respiratory disease	6.1	13.6	18.1	-3.0	-4.3
Ever had bowel cancer screening	5.9	6.9	12.2	1.3	3.5
Suffer from ‘nerves’	5.7	8.9	12.3	-3.5	-2.3
Medication: Simvastatin	5.6	8.2	10.6	2.4	3.3
Hypertension (Self-reported)	5.5	15.3	24.1	2.5	4.9
Vascular/heart problems diagnosed by doctor	5.5	15.0	22.6	-2.7	-4.8
Age at first live birth	5.3	9.3	11.9	2.6	3.4
Medication: Blood pressure	5.3	10.0	16.0	2.0	4.0
Fed-up feelings	5.1	9.2	10.0	-3.2	-2.9
Medication: Lisinopril	5.1	6.7	9.1	2.0	3.0
Allergy or Eczema	5.0	13.1	19.8	-2.5	-4.5
High blood pressure	4.9	13.7	22.2	2.3	4.7
Hayfever, allergic rhinitis or eczema	4.9	10.7	17.9	-1.9	-4.2
Medication: Aspirin	4.9	6.4	7.6	2.3	2.8
Qualifications: CSEs or equivalent	4.7	6.2	6.9	-2.6	-2.4
Ever used hormone-replacement therapy (HRT)	4.5	5.8	6.2	-2.3	-2.5
Systolic Blood Pressure	4.3	21.3	31.4	3.4	5.6
Mouth/teeth dental problems	4.3	6.6	8.1	2.8	2.3
Mean time to correctly identify matches	4.3	8.3	15.2	1.2	3.9
Bipolar Disorder (2018)	4.1	6.5	7.6	2.3	2.8
Medication: Aspirin	4.1	5.4	6.9	1.9	2.6
Medication: Bendroflumethiazide	4.1	6.2	12.4	0.3	3.5
Coronary Artery Disease (CAD)	4.0	4.8	5.0	2.1	2.2
Myopia	3.9	5.6	6.5	2.2	2.6
Medication: Gliclazide	3.8	4.3	7.4	1.1	2.7
Ever taken oral contraceptive pill	3.8	4.3	5.1	-1.9	-2.3
Medication: Co-codamol	3.6	4.2	6.4	-1.4	-2.5
Medication: Ramipril	3.6	4.6	8.5	0.8	2.9
High cholesterol (Self-reported)	3.6	6.5	6.7	2.6	2.5
Systolic blood pressure, automated reading	3.5	10.1	16.1	2.0	4.0
Medication: Atenolol	3.5	4.3	6.2	1.6	2.5
Exposure to tobacco smoke at home	3.5	4.0	4.6	-2.1	-1.8
Pain experienced in last month	3.5	5.8	6.2	2.3	2.5
Number of live births	3.4	4.9	6.4	-2.5	-1.8
Medication: Ventolin 100micrograms inhaler	3.4	4.4	5.0	-2.2	-2.0
Qualifications: College or University degree	3.4	10.7	12.3	3.0	3.5
Miserableness	3.4	5.9	9.8	-3.1	-1.4
Medication: Seretide 50 evohaler	3.3	3.8	5.2	-2.3	-1.5
Age at First Birth	3.2	4.6	5.1	2.0	2.3
Primary Biliary Cirrhosis	3.2	4.5	6.8	1.5	2.6
Ever highly irritable/argumentative for 2 days	3.2	3.8	3.9	-1.9	-2.0
Number of full brothers	3.1	3.9	5.4	-1.6	-2.3
Ever had prostate specific antigen (PSA) test	3.1	3.6	3.9	1.8	2.0
Reaction Time	3.0	5.8	8.2	1.8	2.9
Medication: Cholesterol lowering	2.9	4.6	5.5	1.9	2.3
Pain type(s) experienced in last month: Hip pain	2.8	3.6	6.2	-1.0	-2.5
Townsend deprivation index at recruitment	2.7	3.8	5.8	-1.3	-2.4
Financial difficulties in last 2 years	2.7	3.6	7.1	-0.4	-2.7
Birth weight of first child	2.7	4.8	6.2	-2.5	-1.9
Neuroticism score	2.6	5.4	6.6	-2.6	-2.0
HDL Cholesterol	2.5	4.2	7.4	-2.7	-1.0
Tinnitus: Yes, but not now, but have in the past	2.5	2.7	4.6	-2.1	-0.9
Serious illness, injury or assault of a close relative in last 2 years	2.5	2.9	2.9	1.7	1.7
Basal cell carcinoma (self-reported)	2.5	2.9	4.0	2.0	1.4
Illnesses of father: None of the above (group 1)	2.4	3.0	3.5	-1.9	-1.6
Severe depression (siblings)	2.3	2.5	3.4	1.3	1.8
Sensitivity / hurt feelings	2.2	3.8	3.8	-2.0	-1.9
Back pain experienced in last month	2.2	3.3	4.6	-1.4	-2.1
Ulcerative Colitis (UC)	2.1	3.9	7.8	-0.1	2.8
Ever had hysterectomy (womb removed)	2.1	2.4	2.7	-1.6	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.8	3.2	-1.8	-1.5
Ever unenthusiastic/disinterested for a whole week	2.1	2.5	3.6	-1.2	-1.9
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.6	3.7	-1.9	-1.3
Headache pain in last month	2.1	3.5	4.2	-1.7	-2.1
Pulse rate, automated reading	2.1	6.8	12.6	-1.0	-3.5
Schizophrenia vs Biploar Disorder	2.0	2.6	3.9	-2.0	-1.1
Pulse rate	2.0	3.3	5.1	-1.2	-2.3
Pulse wave reflection index	2.0	2.5	3.2	1.3	1.8
Ulcerative Colitis	1.9	2.8	5.0	0.8	2.2
Medication: Ibuprofen	1.9	2.3	2.6	-1.4	-1.6
Breast cancer (self-reported)	1.9	2.2	2.3	1.5	1.5
Breast Cancer	1.8	4.2	5.2	-1.8	2.3
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	3.0	-1.7	-1.6
Mouth/teeth dental problems: Bleeding gums	1.8	2.3	3.6	-1.9	-1.0
Medication for cholesterol	1.8	2.7	4.8	-0.8	-2.2
Risk taking	1.8	2.6	4.9	2.2	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.7	2.7	4.1	-1.1	-2.0
Pulse wave peak to peak time	1.7	2.0	2.6	-1.2	-1.6
Alcohol usually taken with meals	1.6	2.6	2.9	1.5	1.7
Overall health rating	1.6	3.3	4.3	-1.6	-2.1
Chest pain or discomfort	1.6	2.3	2.8	-1.7	-1.4
Average weekly red wine intake	1.6	2.4	4.7	0.4	2.2
Alzheimer’s Disease (including proxy)	1.5	2.2	4.4	2.1	0.2
Lupus	1.5	2.3	4.4	-0.3	2.1
Emphysema/chronic bronchitis	1.5	1.7	3.2	-0.5	-1.8
Age at last live birth	1.5	2.2	4.3	0.3	2.1
Knee pain experienced in last month	1.5	2.3	3.6	-1.0	-1.9
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.7	3.1	1.8	-0.5
Financial situation satisfaction	1.5	1.8	3.1	-0.7	-1.8
Unable to work because of sickness or disability	1.5	2.0	4.0	0.0	-2.0
Nervous feelings	1.4	2.6	3.1	-1.8	-1.5
Pulse wave Arterial Stiffness index	1.4	1.7	2.1	1.1	1.5
Chronic bronchitis/emphysema (mother)	1.4	1.6	2.8	-0.6	-1.7
Mouth/teeth dental problems: Loose teeth	1.4	1.6	3.2	-0.0	-1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	2.1	1.5	1.1
Medication for hormone replacement therapy	1.3	1.4	1.8	-1.0	-1.3
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	2.1	-1.0	-1.4
Had other major operations	1.3	1.6	2.1	-1.0	-1.4
Prospective memory result	1.3	1.6	1.9	-1.1	-1.4
Eye problems/disorders: None of the above	1.3	1.4	2.4	-0.7	-1.5
Neck or shoulder pain in last month	1.3	1.9	2.5	-1.1	-1.6
Illnesses of siblings: Diabetes	1.3	1.6	1.7	-1.2	-1.3
Illnesses of father: High blood pressure	1.3	1.6	3.0	0.5	1.7
HbA1C	1.2	1.3	2.5	-0.3	1.6
Neuroticism (2016)	1.2	1.8	1.9	-1.4	-1.3
Blood Eosinophil Count	1.2	9.2	17.9	0.8	4.2
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	3.0	-0.4	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	3.0	0.5	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	1.7	-1.3	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	4.9	0.3	-2.2
Smoking status: Current	1.2	1.9	2.7	-1.1	-1.6
Cholesterol lowering medication	1.2	1.7	2.2	1.5	1.1
Maternal smoking around birth	1.1	1.6	2.8	0.6	-1.7
Sitting height	1.1	7.8	12.0	-1.9	-3.5
Mouth/teeth dental problems: Dentures	1.1	1.9	2.9	-1.0	-1.7
Breastfed as a baby	1.1	1.3	1.6	1.3	1.0
Medication: Omeprazole	1.1	1.3	2.1	1.5	0.7
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	2.7	-1.6	-0.0
Diabetes diagnosed by doctor	1.1	1.8	3.7	-0.1	1.9
Eye problems/disorders: Cataract	1.1	1.2	1.4	1.2	1.0
Ever depressed for a whole week	1.1	1.3	2.0	-0.8	-1.4
Commuting to job workplace: Cycle	1.1	1.4	1.8	1.4	0.9
Depressed Affect (Nagel 2018)	1.0	2.0	2.7	-1.6	-1.2
Alzheimer’s Disease (in mother)	1.0	1.2	2.2	1.5	0.4
Mean Putamen Volume	1.0	1.1	1.6	-0.8	-1.3
Relative age of first facial hair	1.0	2.1	3.0	1.7	1.0
Current tobacco smoking	1.0	1.6	2.5	-0.8	-1.6
Waist circumference	1.0	3.6	7.1	2.7	0.5
Hip circumference	1.0	4.4	4.5	-2.1	-2.1
Alcohol intake versus 10 years previously	1.0	1.5	1.7	-1.2	-1.3
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	2.8	-1.7	-0.7
Lung cancer (father)	1.0	1.1	1.8	0.7	-1.4
Heart disease (mother)	1.0	1.2	1.7	-1.3	0.9
Leg pain on walking	1.0	1.3	2.0	1.4	-0.7
Diastolic blood pressure, automated reading	1.0	3.3	5.7	0.9	2.4
Blood Platelet Count	0.9	10.2	14.1	-2.5	-3.8
Blood Red Count	0.9	8.3	16.4	4.0	0.5
Neuroticism	0.9	2.2	4.3	-2.1	-0.4
Serious illness, injury or assault to yourself	0.9	1.1	2.0	-0.4	-1.4
Supplements: Glucosamine	0.9	1.1	1.3	0.9	-1.2
Illnesses of mother	0.9	1.2	2.2	1.5	-0.3
Loud music exposure frequency	0.9	1.0	1.9	1.4	0.2
Blood clot in the leg (DVT)	0.9	1.2	1.8	-1.4	-0.8
Loneliness, isolation	0.9	1.2	1.4	-1.0	-1.2
Medication: Paracetamol	0.9	1.4	1.6	-1.3	-1.1
Fractured/broken bones in last 5 years	0.9	1.1	1.8	1.4	-0.6
Chronic bronchitis/emphysema (father)	0.8	1.0	1.8	0.4	-1.4
Qualifications: A levels/AS levels or equivalent	0.8	1.8	2.7	1.6	0.9
Glaucoma (self-reported)	0.8	0.9	1.8	0.2	1.4
Health satisfaction	0.8	1.0	1.9	0.2	-1.4
Handedness (chirality/laterality): Left-handed	0.8	1.0	1.2	1.1	0.9
Mineral and other dietary supplements	0.8	1.1	1.8	-1.4	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	1.4	1.2	0.7
Bipolar Disorder or Schizophrenia	0.7	1.7	2.8	0.7	1.7
Neuroticism (Nagel 2018)	0.7	1.5	2.7	-1.6	-0.7
Worry (Nagel 2018)	0.7	1.5	2.5	-1.6	-0.7
Irritable Bowel Disease (IBD)	0.7	1.7	2.9	-0.7	1.7
Body Mass Index (BMI) (2010)	0.7	1.0	1.2	-0.8	-1.1
Hypothyroidism (self reported)	0.7	1.7	3.2	-1.8	0.4
Multivitamins +/- minerals	0.7	0.9	1.8	-0.2	-1.4
Qualifications: None of the above	0.7	1.6	2.2	-1.0	-1.5
Worrier / anxious feelings	0.7	1.4	2.7	-1.6	0.1
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	2.3	-1.5	0.7
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.1	-1.5	0.1
Ever smoked	0.7	1.1	1.3	-1.0	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.5	-1.2	-0.4
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.1	0.6	1.1
Smoking Status	0.6	1.5	2.2	-1.5	-0.9
Medication: Metformin	0.6	0.8	1.6	-0.2	1.3
Medication: Paracetamol	0.6	1.0	1.5	-1.2	-0.8
Guilty feelings	0.6	0.8	1.3	-0.6	-1.2
Age started oral contraceptive pill	0.6	0.8	1.5	0.1	1.2
Intelligence (Savage-Jansen 2018)	0.5	1.6	1.9	-1.2	-1.4
Lung FVC	0.5	2.8	4.2	1.1	2.1
Diabetes (father)	0.5	0.6	1.0	-1.0	0.5
Father’s age at death	0.5	0.7	1.4	-1.2	-0.0
Tense / ‘highly strung’	0.5	0.8	0.8	-0.9	-0.8
High blood pressure (siblings)	0.5	0.7	1.4	0.1	1.2
Number of children fathered	0.5	0.5	0.8	0.5	-0.9
Number of full sisters	0.5	0.7	1.0	-0.5	-1.0
Long-standing illness, disability or infirmity	0.5	0.8	1.2	-1.1	-0.7
Commuting to job workplace: Walk	0.5	0.6	0.7	0.7	0.8
Commuting to job workplace: Public transport	0.5	0.6	0.9	-0.5	-0.9
Ovarian Cancer	0.4	0.6	0.9	-0.4	1.0
Triglycerides	0.4	0.6	1.1	0.3	-1.0
Height	0.4	8.1	16.1	0.3	-4.0
Lung FEV1/FVC ratio	0.4	1.9	2.0	-1.4	-1.3
Number of treatments/medications taken	0.4	0.6	1.2	0.3	1.1
Supplements: Zinc	0.4	0.4	0.5	-0.6	-0.7
Leg fat-free mass (left)	0.4	2.1	3.0	-1.1	-1.7
High blood pressure (mother)	0.4	0.5	1.1	-0.1	1.0
Leg predicted mass (left)	0.4	2.0	3.0	-1.0	-1.7
Diabetes (self-reported)	0.4	0.6	0.8	-0.7	0.9
Falls in the last year	0.4	0.5	1.0	-1.0	0.1
Hair/balding pattern: Pattern 3	0.4	0.6	0.7	0.6	0.9
Noisy workplace	0.4	0.5	0.6	0.7	0.7
Forced vital capacity (FVC), Best measure	0.4	1.6	3.1	-0.2	-1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	0.7	-0.9	-0.5
Comparative height size at age 10	0.4	2.4	4.4	-0.6	-2.1
Had major operations	0.4	0.5	0.6	0.8	0.6
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	0.6	0.8	0.6
Friendships satisfaction	0.4	0.5	0.9	-0.9	-0.5
Alcohol drinker status: Never	0.4	0.5	1.0	0.1	-1.0
Supplements: Calcium	0.4	0.5	0.8	0.9	0.4
Crohns Disease (2017)	0.3	0.6	0.8	-0.9	-0.6
Major Depression (MDD)	0.3	0.4	0.8	-0.9	-0.1
Prostate Cancer	0.3	0.5	0.9	-0.0	0.9
Fasting Glucose	0.3	0.3	0.6	-0.7	-0.3
Type 2 Diabetes (T2D) (2018)	0.3	0.5	0.9	-0.3	1.0
Average weekly spirits intake	0.3	0.4	0.7	-0.8	0.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.8	0.9	0.3
Average weekly fortified wine intake	0.3	0.3	0.6	-0.2	0.7
Number of incorrect matches in round	0.3	0.4	0.8	0.3	0.9
Pain all over the body in last month	0.3	0.3	0.4	-0.3	0.7
Fluid intelligence score	0.3	0.7	1.1	1.1	0.5
Trunk fat-free mass	0.3	1.7	3.2	-0.3	-1.8
Medication: Lansoprazole	0.3	0.3	0.5	-0.7	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	1.9	-0.3	-1.4
Trunk predicted mass	0.3	1.6	3.2	-0.2	-1.8
Standing height	0.3	2.7	5.0	0.6	-2.2
Length of working week for main job	0.3	0.3	0.5	0.3	0.7
Hair/balding pattern: Pattern 4	0.3	0.8	1.5	1.2	-0.0
Arm predicted mass (right)	0.3	1.3	2.5	-0.3	-1.6
Whole body fat-free mass	0.3	1.7	3.1	-0.5	-1.8
Mood swings	0.3	0.5	0.5	-0.7	-0.7
Qualifications: nursing, teaching	0.3	0.4	0.6	0.8	0.5
Whole body water mass	0.3	1.5	2.9	-0.4	-1.7
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.3	0.5	-0.6
Basal metabolic rate	0.3	1.6	3.0	-0.4	-1.7
Number of operations (self-reported)	0.3	0.4	0.5	0.7	-0.6
Average weekly beer plus cider intake	0.3	0.5	0.8	0.9	-0.4
Heart disease (siblings)	0.3	0.3	0.5	-0.7	-0.3
Pack years of smoking	0.3	0.5	0.6	0.8	0.7
Arm predicted mass (left)	0.3	1.5	3.0	0.1	-1.7
Depression (Nagel 2018)	0.2	0.3	0.6	-0.8	-0.3
Schizophrenia (2018)	0.2	0.4	0.8	-0.9	-0.1
Alzheimer’s Disease (in father)	0.2	0.2	0.3	0.5	-0.3
Rheumatoid Arthritis	0.2	0.2	0.3	0.5	0.5
Blood White Count	0.2	1.6	2.9	1.7	0.6
Impedance of leg (right)	0.2	0.8	0.8	0.9	-0.9
Relative age voice broke	0.2	0.3	0.3	0.6	-0.5
Stomach or abdominal pain in last month	0.2	0.3	0.5	-0.3	-0.7
Medication: Levothyroxine sodium	0.2	0.3	0.5	-0.7	0.4
Impedance of leg (left)	0.2	1.2	2.4	1.5	-0.1
Hair/balding pattern: Pattern 2	0.2	0.3	0.5	-0.2	-0.7
Had menopause	0.2	0.3	0.4	-0.6	-0.4
Forced vital capacity (FVC)	0.2	0.9	1.8	0.1	-1.3
Weight	0.2	0.8	1.4	-0.4	-1.2
Time employed in main current job	0.2	0.2	0.4	0.2	0.6
Medication: Amlodipine	0.2	0.3	0.5	0.3	0.7
Arm fat-free mass (right)	0.2	0.8	1.6	-0.0	-1.3
Exposure to tobacco smoke outside home	0.2	0.3	0.3	-0.5	0.5
Medication for pain relief, constipation, heartburn	0.2	0.3	0.4	0.7	0.4
Migraine (self-reported)	0.2	0.2	0.4	0.6	-0.3
Alcohol intake frequency.	0.2	0.4	0.9	-0.9	0.0
Supplements: Vitamin C	0.2	0.2	0.4	0.2	0.6
Leg fat-free mass (right)	0.2	1.3	1.9	-0.8	-1.4
Arm fat percentage (left)	0.2	0.8	1.4	-1.2	-0.3
Osteoporosis (self-reported)	0.2	0.3	0.5	0.3	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.5	0.7	0.5
Leg predicted mass (right)	0.2	1.2	1.9	-0.8	-1.4
Arm fat mass (left)	0.2	0.8	0.9	-1.0	-0.8
Mother’s age at death	0.2	0.2	0.4	0.6	0.2
Eye problems/disorders: Glaucoma	0.2	0.2	0.4	0.2	0.6
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.4	-0.6	-0.4
Arm fat-free mass (left)	0.2	0.9	1.7	0.1	-1.3
Alcohol drinker status: Previous	0.2	0.2	0.4	-0.7	-0.1
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.2	-0.5	-0.2
LDL Cholesterol	0.1	0.1	0.1	-0.2	-0.3
Schizophrenia (2014)	0.1	0.3	0.5	-0.7	0.1
Heel T-Score	0.1	0.5	1.0	-1.0	-0.2
Chronotype (morning person)	0.1	0.2	0.2	0.4	0.5
Hair Pigment	0.1	3.6	5.5	-1.3	2.4
Hand grip strength (left)	0.1	0.3	0.4	0.4	-0.7
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.2	-0.4	-0.3
Hearing difficulty/problems: Yes	0.1	0.2	0.3	-0.2	-0.5
Angina	0.1	0.2	0.3	0.6	-0.0
Vitamin and mineral supplements	0.1	0.2	0.2	-0.4	0.4
Pack years adult smoking proportion	0.1	0.2	0.4	0.6	-0.1
Trunk fat percentage	0.1	0.2	0.3	-0.6	-0.4
Taking other prescription medications	0.1	0.2	0.2	-0.4	-0.4
Age when periods started (menarche)	0.1	0.2	0.3	0.6	-0.2
Body mass index (BMI)	0.1	0.5	0.9	-0.9	-0.5
Trunk fat mass	0.1	0.3	0.3	-0.4	-0.6
Past tobacco smoking	0.1	0.1	0.2	0.5	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.4	0.3	-0.6
Heart attack	0.1	0.2	0.3	-0.1	-0.5
Illnesses of siblings	0.1	0.1	0.1	0.3	-0.3
Arm fat percentage (right)	0.1	0.3	0.6	-0.8	-0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.7	0.2	-0.8
Happiness	0.1	0.1	0.1	0.4	0.1
Impedance of arm (left)	0.1	0.3	0.4	-0.6	-0.4
Arm fat mass (right)	0.1	0.5	0.5	-0.7	-0.7
Body fat percentage	0.1	0.2	0.3	-0.6	-0.3
Leg fat percentage (right)	0.1	0.3	0.3	-0.5	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	-0.1	0.5
Angina (self-reported)	0.1	0.1	0.1	0.2	-0.3
Whole body fat mass	0.1	0.6	0.6	-0.7	-0.8
Leg fat mass (right)	0.1	0.4	0.6	-0.4	-0.8
Smoking status: Previous	0.1	0.2	0.4	-0.1	0.6
Average weekly champagne plus white wine intake	0.1	0.2	0.3	0.5	0.2
Hearing aid user	0.1	0.1	0.1	0.4	0.3
Medication: Atorvastatin	0.1	0.2	0.3	-0.5	-0.2
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.2	0.0	-0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.1	-0.0	0.3
BMI	0.0	0.1	0.1	-0.2	-0.3
Tanning	0.0	0.5	0.6	0.8	0.6
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.0	-0.1	-0.1
Diabetes (mother)	0.0	0.0	0.1	0.2	0.1
Hand grip strength (right)	0.0	0.1	0.1	0.3	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.0	-0.0	0.1
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.1	-0.1	0.2
Hearing difficulty/problems with background noise	0.0	0.0	0.0	0.1	0.0
Impedance of arm (right)	0.0	0.0	0.0	0.0	-0.0
Depression (self-reported)	0.0	0.1	0.1	0.3	-0.1
Peak expiratory flow (PEF)	0.0	0.1	0.1	0.1	-0.4
Qualifications: O levels/GCSEs or equivalent	0.0	0.1	0.1	-0.0	-0.4
Gout (self-reported)	0.0	0.0	0.0	0.1	0.2
Comparative body size at age 10	0.0	0.0	0.0	-0.1	0.0
Worry too long after embarrassment	0.0	0.1	0.1	-0.3	-0.1
Medication: Allopurinol	0.0	0.1	0.1	0.1	0.3
Family relationship satisfaction	0.0	0.0	0.1	0.3	-0.1
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.0	-0.0	0.0
Number of self-reported non-cancer illnesses	0.0	0.0	0.0	-0.0	-0.1
Leg fat percentage (left)	0.0	0.0	0.0	-0.0	-0.0
Irritability	0.0	0.0	0.0	0.1	0.0
Impedance of whole body	0.0	0.1	0.2	0.1	-0.4
Leg fat mass (left)	0.0	0.1	0.2	-0.2	-0.4

Hub : Genes

HSPB2

Models

Trait associations