Hub : Genes

ZSWIM5

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0720	0.0250	7.0e-06	0.009	0.038	0.010	0.038	0.018	2.4e-02	1.9e-05	1.9e-02	1.6e-05	2.4e-03
2	GTEx	Adipose Subcutaneous	0.1340	0.0440	8.1e-06	0.067	NA	0.095	NA	0.085	4.0e-06	NA	3.5e-08	NA	1.9e-07
3	GTEx	Adipose Visceral Omentum	0.1270	0.0430	1.4e-04	0.090	NA	0.059	NA	0.065	2.1e-05	NA	5.2e-04	NA	2.8e-04
4	GTEx	Artery Aorta	0.1340	0.0520	1.4e-03	0.054	NA	0.050	NA	0.061	6.4e-04	NA	9.2e-04	NA	2.7e-04
5	GTEx	Breast Mammary Tissue	0.1400	0.0670	3.4e-03	0.055	NA	0.020	NA	0.045	8.2e-04	NA	3.1e-02	NA	2.4e-03
6	GTEx	Breast Mammary Tissue (Male)	0.1560	0.0865	2.6e-02	0.071	NA	0.016	NA	0.053	9.9e-03	NA	1.3e-01	NA	2.3e-02
7	GTEx	Cells Transformed fibroblasts	0.1740	0.0630	1.1e-04	0.031	NA	0.032	NA	0.023	2.2e-03	NA	1.8e-03	NA	7.4e-03
8	GTEx	Heart Atrial Appendage	0.1100	0.0550	5.6e-03	0.095	NA	0.028	NA	0.086	4.8e-05	NA	2.1e-02	NA	1.1e-04
9	GTEx	Nerve Tibial	0.0763	0.0307	1.6e-03	0.060	NA	0.069	NA	0.068	4.8e-05	NA	1.2e-05	NA	1.4e-05
10	GTEx	Pancreas	0.1360	0.0630	4.0e-03	0.017	NA	0.010	NA	0.034	6.4e-02	NA	1.2e-01	NA	1.4e-02
11	GTEx	Thyroid	0.1240	0.0610	1.9e-03	0.080	NA	0.069	NA	0.065	1.1e-06	NA	5.9e-06	NA	1.0e-05
12	YFS	Blood	0.0343	0.0135	2.1e-04	0.022	0.009	0.011	0.016	0.020	7.9e-08	3.8e-04	1.2e-04	5.2e-06	1.9e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	0.2	0.4	1.4	1.0	0.0	-0.1	-0.3	0.4	0.3	-0.3	0.9	0.0	-0.7	0.6	1.2
Bipolar Disorder or Schizophrenia	0.1	0.2	1.9	1.4	-0.1	-0.1	-0.2	0.1	0.1	-0.2	0.1	-0.2	-0.2	0.7	0.2
Depressed Affect (Nagel 2018)	1.1	2.3	6.2	-1.2	-1.6	-1.7	-1.0	-1.4	-1.5	-2.5	-1.2	-1.6	2.2	-0.7	-0.5
Depression (Nagel 2018)	0.4	0.7	1.7	-0.7	-1.0	-1.1	-0.8	-0.3	-0.4	-0.6	-1.0	-0.9	1.3	-0.5	-0.4
Intelligence (Savage-Jansen 2018)	0.8	2.6	10.6	1.6	1.4	1.3	1.4	-1.5	-1.4	-0.3	3.3	1.1	-1.5	1.6	1.0
Neuroticism (Nagel 2018)	0.6	1.4	3.1	-1.1	-1.4	-1.4	-1.0	-1.5	-1.6	-0.7	-0.8	-1.8	0.3	-1.0	0.7
Schizophrenia (2018)	0.1	0.2	1.0	1.0	-0.1	-0.0	-0.0	-0.2	-0.1	0.2	-0.6	-0.3	0.3	0.4	-0.7
Schizophrenia vs Biploar Disorder	0.6	0.8	2.2	-0.1	-0.6	-0.4	-0.6	-1.1	-1.1	-1.2	-1.0	-0.7	1.0	-1.5	-0.5
Worry (Nagel 2018)	0.4	0.9	1.9	-0.4	-1.0	-1.0	-0.6	-1.2	-1.2	-0.9	-1.0	-1.4	0.3	-0.9	0.3
Alzheimer’s Disease (in mother)	0.6	0.7	1.7	-0.0	-1.0	-1.1	-1.0	-0.5	-0.6	0.9	-1.3	-1.2	-0.2	-0.9	-0.2
Alzheimer’s Disease (in father)	0.5	0.6	2.1	-0.1	-0.1	0.2	0.4	-0.1	-0.1	-1.5	-1.1	0.6	1.0	1.0	-1.0
Alzheimer’s Disease (including proxy)	0.3	0.4	2.3	-0.1	-0.6	-0.7	-0.5	0.3	0.2	0.1	-1.5	-0.5	0.5	0.2	-0.9
Crohns Disease (2017)	2.8	6.1	12.3	-1.8	-3.0	-3.0	-2.8	-3.4	-3.5	-1.3	-1.8	-2.6	-0.5	-2.7	1.3
Irritable Bowel Disease (IBD)	2.1	5.0	11.8	-0.6	-2.6	-2.6	-2.6	-2.8	-2.9	-1.3	-0.7	-3.4	0.4	-2.9	0.3
Ulcerative Colitis (UC)	1.2	2.3	8.5	0.7	-1.4	-1.5	-1.5	-1.7	-1.7	-0.8	0.3	-2.9	1.1	-1.9	-0.4
Major Depression (MDD)	0.4	0.5	2.1	-0.1	0.4	0.5	0.2	0.7	0.7	0.9	0.1	1.0	-1.4	0.3	1.1
Reaction Time	0.8	1.5	4.8	0.4	-1.1	-0.9	-0.7	-2.2	-2.2	-0.4	-0.7	-1.3	1.2	-1.3	0.1
Verbal and Numeric Reasoning (VNR)	0.7	1.8	9.7	1.0	1.2	1.0	1.1	-1.4	-1.3	0.0	3.1	0.7	-1.1	0.7	1.1
Breast Cancer	1.4	3.4	11.0	2.5	0.2	-0.2	0.2	-3.0	-2.8	-1.8	3.3	-1.3	1.0	0.7	-0.5
Ovarian Cancer	0.6	0.8	2.3	-0.4	0.7	0.7	0.9	1.5	1.4	0.3	0.8	0.7	-0.9	1.1	0.1
Prostate Cancer	1.3	1.8	6.0	-0.9	-1.6	-1.5	-1.3	-1.0	-1.1	-1.2	-2.5	-1.2	0.9	-1.7	-0.1
Age at First Birth	0.4	0.6	1.8	-0.4	-0.4	-0.3	-0.5	-1.3	-1.3	-0.3	0.6	-0.8	-0.9	-0.2	0.7
Bipolar Disorder (2011)	0.7	0.7	2.8	-0.2	-0.6	-0.8	-0.8	0.7	0.6	0.3	0.3	-1.4	-1.1	-0.5	1.7
Body Mass Index (BMI) (2010)	0.3	0.4	1.6	-1.3	-0.6	-0.6	-0.5	0.5	0.5	0.2	-0.8	0.3	-0.3	0.2	0.3
Coronary Artery Disease (CAD)	0.6	0.7	2.3	-0.7	0.0	0.1	0.1	1.3	1.5	1.0	-1.0	-1.3	-0.6	-0.3	-0.2
Crohns Disease (2012)	2.4	3.9	9.1	-1.6	-2.2	-2.2	-2.0	-2.9	-3.0	-1.9	-1.3	-2.0	-0.3	-1.7	0.6
Mean Putamen Volume	0.4	0.5	1.2	-0.2	-0.9	-1.0	-1.1	0.6	0.5	0.1	0.1	-0.9	-0.5	-0.8	0.4
Fasting Glucose	3.0	3.6	7.2	-2.7	-2.2	-2.2	-2.7	1.1	0.8	-0.0	-2.4	-1.7	-1.4	-2.0	1.6
HbA1C	2.2	2.5	6.7	-2.1	-1.0	-1.0	-1.5	0.7	0.6	2.0	-1.0	-0.9	-2.6	-1.9	2.0
HDL Cholesterol	0.2	0.4	1.3	-0.2	0.3	0.2	-0.0	0.9	0.9	1.2	-0.3	0.4	-1.0	0.2	0.1
LDL Cholesterol	0.8	1.2	1.9	0.7	1.2	1.3	1.4	1.4	1.4	1.1	1.1	1.3	-0.8	0.6	0.3
Lupus	0.8	1.2	3.9	1.3	1.1	1.0	0.9	-0.6	-0.5	-0.2	2.0	1.4	-1.1	1.1	0.9
Neuroticism (2016)	0.5	0.7	3.0	0.3	-0.3	-0.3	-0.2	-1.7	-1.7	-0.3	0.9	-1.0	-0.5	0.7	0.2
Primary Biliary Cirrhosis	2.0	2.8	10.5	-1.7	-2.0	-2.0	-2.0	-0.2	-0.5	-0.0	-0.9	-0.9	-2.3	-1.1	3.2
Rheumatoid Arthritis	0.5	0.7	1.9	-0.6	-1.0	-0.9	-0.6	0.8	0.6	0.5	-1.2	-0.5	-0.6	-1.1	1.4
Schizophrenia (2014)	0.3	0.6	1.0	1.0	-0.6	-0.6	-0.4	-1.0	-1.0	-1.0	-1.0	-1.0	0.6	-0.2	-0.2
Triglycerides	0.0	0.1	0.2	-0.5	0.2	0.1	0.3	-0.1	-0.1	-0.2	-0.0	-0.1	0.4	-0.2	-0.4
Type 2 Diabetes (T2D) (2012)	1.8	2.1	6.8	-2.3	-1.9	-1.6	-1.6	0.4	0.2	0.3	-2.6	-1.5	0.3	-1.5	-0.1
Ulcerative Colitis	0.4	0.5	2.3	0.6	-0.1	-0.4	-0.5	-0.2	-0.2	-0.1	1.4	-1.5	0.4	-0.9	-0.3
Blood Eosinophil Count	0.2	1.2	5.4	-2.3	-0.6	-0.4	-0.3	0.5	0.3	-0.8	-1.6	0.1	2.1	-0.9	-0.1
Blood Platelet Count	4.5	52.6	246.5	-10.1	-8.9	-7.8	-7.7	1.4	0.5	-1.2	-15.7	-3.6	4.2	-6.9	-1.5
Blood Red Count	0.7	6.3	25.3	3.4	2.4	1.8	2.5	-2.3	-1.9	-1.3	5.0	-2.7	2.0	0.2	-1.3
Blood White Count	1.3	9.3	30.2	-1.6	-2.7	-2.7	-2.0	-1.4	-1.5	-4.0	-3.5	-3.2	5.5	-3.6	-2.1
Heel T-Score	1.1	8.9	19.6	2.3	4.3	3.9	4.1	2.3	2.7	1.3	4.4	2.2	-1.3	3.1	-1.4
BMI	0.3	1.6	4.7	-1.8	-0.7	-0.5	-1.0	1.2	1.0	1.4	-0.9	1.5	-2.2	0.1	1.7
Height	0.8	16.3	42.5	-2.0	-4.3	-4.7	-4.3	-4.5	-4.7	-2.7	0.1	-6.5	-0.2	-4.3	4.7
Waist Hip Ratio (WHR)	1.7	7.5	16.1	4.0	3.2	3.1	3.2	2.2	2.4	0.1	2.0	2.6	2.1	2.4	-3.4
Systolic Blood Pressure	0.4	1.9	9.3	-1.6	-0.4	-0.0	-0.2	1.6	1.6	2.1	-3.0	0.7	-0.8	-0.1	-0.7
Smoking Status	0.5	1.2	7.8	-0.1	-0.6	-0.4	-0.3	1.3	1.3	-0.3	-2.8	0.6	1.0	0.3	-0.7
Allergy or Eczema	0.4	1.0	3.1	-1.4	0.1	0.2	-0.1	1.8	1.7	1.7	0.2	0.5	-0.2	-0.3	0.7
Cardiovascular Disease	0.4	1.3	5.6	-1.0	-0.5	-0.2	0.0	-0.1	-0.1	0.2	-2.4	0.4	2.2	0.3	-1.9
Hypothyroidism (self reported)	0.7	1.6	5.4	-2.3	-0.9	-0.7	-0.8	0.9	0.7	0.7	-0.8	0.3	-1.9	-0.6	2.2
Respiratory disease	1.7	3.7	10.5	1.3	2.3	2.6	2.4	-0.2	-0.1	0.9	2.2	3.2	0.5	2.5	-1.6
Type 2 Diabetes (T2D) (2018)	0.5	1.0	4.0	0.0	0.7	0.6	0.9	1.9	2.0	0.4	-1.0	1.1	-0.1	0.6	-0.1
Lung FEV1/FVC ratio	2.1	10.6	24.5	-4.9	-3.2	-2.8	-3.5	0.8	0.4	3.3	-3.9	-1.1	-5.0	-1.9	4.1
Lung FVC	0.8	4.1	9.9	-2.2	-2.4	-2.5	-2.1	-0.6	-0.7	-0.9	-2.7	-3.1	0.3	-2.8	0.9
Neuroticism	0.7	1.7	6.0	0.1	-0.6	-0.9	-0.2	-2.2	-2.2	-2.5	0.2	-1.6	0.7	0.1	-0.4
Chronotype (morning person)	0.7	1.7	5.4	1.8	1.6	1.5	1.3	-0.7	-0.5	-0.8	2.3	1.1	0.3	1.4	-0.8
Hair Pigment	0.2	5.0	6.9	-1.5	-2.6	-2.6	-2.3	-2.5	-2.6	-2.4	-2.6	-2.2	1.8	-2.2	-0.9
Tanning	0.0	0.4	1.2	0.0	-0.1	-0.0	-0.4	1.0	0.9	1.1	-0.5	-0.0	-1.1	-0.1	0.9
Hand grip strength (left)	0.3	0.8	5.1	-0.6	-0.1	-0.1	-0.4	0.5	0.5	0.3	0.9	-0.1	-1.5	0.4	2.3
Number of treatments/medications taken	1.7	3.0	8.3	1.0	1.4	1.7	1.2	2.9	2.9	2.2	-0.7	2.1	-0.5	1.1	-0.7
Average weekly spirits intake	1.6	2.0	6.0	-0.7	0.7	0.6	0.5	2.2	2.1	2.0	0.4	0.8	-2.5	0.5	1.2
Sensitivity / hurt feelings	0.7	1.3	4.0	-0.3	-0.9	-1.0	-0.8	-1.5	-1.6	-0.1	0.2	-0.5	-2.0	-0.3	1.8
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.4	-0.5	-0.7	-0.6	-0.3	0.1	0.0	-0.6	-1.2	-0.7	0.4	-0.4	-0.1
Hearing difficulty/problems: Yes	1.6	2.5	11.8	1.9	1.0	0.8	0.8	-1.9	-1.8	-1.8	3.4	0.3	0.7	1.1	-0.5
Relative age of first facial hair	1.3	2.7	6.2	-1.9	-2.0	-2.3	-1.9	-0.7	-0.8	-0.9	-1.9	-2.5	1.6	-1.4	-0.2
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.6	-0.8	0.2	0.3	0.7	0.6	0.6	0.1	0.0	0.5	-0.3	0.2	0.7
Ever used hormone-replacement therapy (HRT)	1.1	1.4	3.5	0.7	1.3	1.5	1.2	1.1	1.0	1.0	1.1	1.9	-0.8	1.6	0.1
Ever had hysterectomy (womb removed)	0.4	0.5	2.7	-1.1	-0.4	-0.1	-0.1	0.7	0.7	0.2	-1.6	0.5	0.1	-0.2	-0.4
Systolic blood pressure, automated reading	0.6	1.7	5.7	-0.9	0.5	0.8	0.6	1.6	1.5	2.4	-1.6	1.8	-1.1	0.8	-0.8
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.7	1.0	0.1	0.1	-0.0	-0.1	-0.1	-1.6	1.0	0.7	1.4	0.4	-1.2
Angina	0.4	0.5	1.6	-0.4	0.7	0.8	1.0	0.1	0.2	0.8	-0.2	1.3	0.0	0.7	-0.8
Medication for hormone replacement therapy	0.5	0.5	2.2	-0.6	0.2	0.1	0.0	1.5	1.5	1.2	0.2	0.1	0.0	-0.0	0.1
Vitamin and mineral supplements	3.0	4.0	10.8	-0.2	-1.7	-1.7	-1.1	-3.2	-3.3	-2.8	-0.2	-1.6	2.6	-1.5	-0.7
Supplements: Zinc	0.4	0.5	2.5	-0.3	-0.7	-0.6	-0.7	0.7	0.6	-0.6	-1.6	-0.3	0.3	-0.4	0.2
Medication: Co-codamol	0.3	0.4	1.4	-0.7	-0.6	-0.4	-0.5	0.6	0.4	0.2	-0.2	0.2	-1.1	-0.0	1.2
Medication: Metformin	2.0	2.8	8.0	1.5	2.0	1.9	2.1	1.3	1.5	0.1	1.4	2.8	0.1	2.2	-0.8
Diabetes (father)	0.7	0.8	3.9	-2.0	-0.8	-0.7	-0.7	0.7	0.6	1.4	-0.9	-0.1	-0.2	-0.8	0.6
Diabetes (mother)	1.1	1.4	3.6	0.2	-1.3	-1.1	-1.2	-1.1	-1.1	-1.4	-1.4	-0.5	1.9	-1.2	-1.0
Severe depression (siblings)	0.1	0.1	0.9	0.3	-0.3	-0.2	-0.2	-0.2	-0.2	0.4	-0.3	-0.3	-0.1	0.9	-0.3
Pack years adult smoking proportion	0.3	0.5	2.2	-0.6	-0.1	0.1	-0.1	1.5	1.3	-0.2	-0.7	0.7	-0.8	0.2	0.2
Impedance of leg (right)	0.1	0.7	1.8	-0.5	0.3	0.6	0.2	0.8	0.8	1.2	-0.6	0.2	1.3	-0.9	-1.3
Leg fat-free mass (left)	0.3	1.7	7.0	-1.4	-1.4	-1.5	-1.5	-0.5	-0.7	-0.6	0.5	-0.8	-1.7	-0.7	2.6
Trunk fat percentage	0.4	1.6	5.5	-2.3	-0.9	-0.5	-1.0	1.1	0.8	1.4	-1.2	0.9	-1.6	-0.6	1.8
Hand grip strength (right)	0.2	0.7	3.1	-0.0	0.2	-0.0	-0.1	0.4	0.5	0.5	1.4	-0.1	-1.5	0.4	1.8
Townsend deprivation index at recruitment	0.1	0.2	0.6	0.8	-0.3	-0.2	-0.1	0.2	0.1	-0.8	0.1	0.5	0.0	-0.4	0.3
Current tobacco smoking	0.8	1.4	3.5	-0.3	0.1	0.5	0.3	1.8	1.7	-0.6	-1.9	1.9	0.7	1.1	-1.1
Average weekly fortified wine intake	2.5	2.9	4.9	0.3	1.5	1.5	1.1	2.1	2.0	1.9	2.2	1.5	-1.9	2.1	1.4
Maternal smoking around birth	1.8	2.6	6.8	1.3	1.4	1.6	1.6	1.1	1.2	-0.6	-0.4	2.4	2.3	1.3	-2.6
Fed-up feelings	1.1	2.0	5.9	-1.4	-1.7	-1.7	-1.1	-1.0	-1.2	-2.4	-1.6	-1.5	1.1	-0.6	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	1.2	-0.8	-0.8	-0.7	-0.6	-0.2	-0.3	-0.8	-1.1	-0.6	0.7	-0.1	-0.6
Relative age voice broke	1.5	2.3	4.5	-1.1	-1.6	-1.9	-1.4	-1.0	-1.1	-1.2	-1.3	-2.1	2.0	-1.8	-0.8
Taking other prescription medications	0.2	0.3	1.3	-0.0	-0.1	-0.0	-0.2	0.7	0.6	0.5	-0.9	1.2	-0.2	0.3	0.1
Age when periods started (menarche)	0.9	2.2	6.6	-2.2	-1.5	-1.5	-1.6	0.3	0.2	0.4	-2.0	-1.7	0.1	-2.6	0.6
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	7.2	-2.7	-1.5	-1.1	-1.5	0.6	0.3	0.3	-1.6	-0.2	-1.6	-1.7	1.9
Heel bone mineral density (BMD) T-score, automated (left)	3.9	8.8	16.6	2.6	4.1	3.9	3.8	2.1	2.5	0.2	3.6	3.2	-0.3	3.8	-2.2
Tinnitus: Yes, but not now, but have in the past	2.1	2.2	7.2	-1.2	-1.6	-1.3	-1.3	-1.5	-1.6	-2.7	-1.4	-0.5	1.8	-1.4	-0.7
Qualifications: CSEs or equivalent	0.5	0.6	2.6	-0.5	-0.5	-0.2	-0.2	-1.0	-1.0	-0.4	-1.6	0.3	0.9	-0.2	-1.0
Serious illness, injury or assault to yourself	0.5	0.6	2.1	0.8	1.1	1.2	1.5	-0.0	0.0	0.7	0.3	0.6	0.2	0.5	-0.8
High blood pressure	0.8	2.1	8.9	-0.3	-0.6	-0.2	-0.2	-1.1	-1.1	-1.4	-1.5	0.2	3.0	0.3	-3.0
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.9	-1.1	-0.1	0.0	-0.5	1.4	1.3	0.9	-0.2	0.2	0.1	-0.5	0.4
Multivitamins +/- minerals	3.5	4.4	12.3	0.4	1.8	1.9	1.4	3.5	3.5	2.8	0.2	1.8	-2.4	1.6	0.4
Stomach or abdominal pain in last month	2.3	2.8	5.8	0.8	1.8	2.0	2.3	0.5	0.6	-0.9	1.0	2.3	1.4	2.2	-2.4
Supplements: Glucosamine	1.4	1.8	5.3	-2.3	-0.7	-0.5	-1.0	1.6	1.4	1.8	-1.6	0.6	-1.5	0.4	1.1
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	4.8	2.2	1.1	1.1	1.2	-1.0	-0.8	-1.5	1.0	1.1	1.5	1.7	-2.0
Medication: Atenolol	0.2	0.3	0.7	-0.2	-0.6	-0.6	-0.3	-0.5	-0.6	-0.6	0.0	-0.3	-0.8	0.2	0.8
Medication: Levothyroxine sodium	0.5	0.9	3.4	-1.1	-0.3	-0.2	-0.1	1.1	0.9	0.2	-0.5	0.8	-1.8	-0.2	1.7
Sitting height	0.9	6.4	21.6	-1.9	-2.6	-3.0	-2.4	-2.8	-2.9	-1.6	-0.3	-4.7	1.0	-2.5	2.1
Chronic bronchitis/emphysema (father)	1.1	1.3	2.2	1.4	1.5	1.4	1.2	0.2	0.3	1.1	1.1	1.3	0.1	1.5	-1.2
High blood pressure (mother)	0.7	1.0	4.2	-0.3	0.7	0.9	0.7	1.3	1.3	0.2	-0.9	0.8	0.8	0.7	-2.0
Body mass index (BMI)	0.3	1.2	3.6	-1.7	-0.9	-0.7	-1.0	0.8	0.5	0.8	-1.0	1.0	-1.9	-0.1	1.5
Impedance of leg (left)	0.1	0.5	1.7	-0.6	0.5	0.7	0.4	0.6	0.5	1.3	-0.3	0.4	0.7	-0.6	-0.8
Leg predicted mass (left)	0.3	1.7	7.0	-1.4	-1.4	-1.5	-1.5	-0.5	-0.7	-0.6	0.5	-0.9	-1.7	-0.7	2.6
Trunk fat mass	0.5	2.2	7.5	-2.7	-1.4	-1.1	-1.5	0.8	0.5	1.3	-1.1	0.4	-1.9	-0.8	2.3
Waist circumference	0.4	1.4	5.4	0.1	0.7	0.9	0.5	1.4	1.3	1.4	1.0	2.3	-1.4	1.1	0.7
Number of incorrect matches in round	0.0	0.1	0.3	-0.1	-0.2	-0.1	-0.1	0.1	0.1	-0.3	-0.4	-0.3	0.5	0.2	-0.3
Past tobacco smoking	0.4	0.7	2.9	0.6	0.6	0.7	0.4	-1.3	-1.2	0.1	1.7	0.1	-0.9	0.1	0.3
Alcohol usually taken with meals	2.3	3.7	9.3	-2.9	-1.9	-2.3	-2.3	0.2	0.0	1.0	-1.1	-3.0	-0.4	-2.4	2.1
Nervous feelings	0.5	1.0	2.6	0.5	-1.1	-1.2	-0.8	-1.5	-1.4	-0.9	-0.5	-1.6	-0.3	-0.3	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.7	-0.1	-0.2	-0.1	0.1	-0.6	-0.6	-0.8	-0.1	0.2	-0.5	0.6	0.3
Hearing difficulty/problems with background noise	0.2	0.3	1.4	-0.1	-0.2	-0.3	-0.6	-0.4	-0.4	-0.5	0.4	-1.2	-0.6	-0.7	0.8
Hair/balding pattern: Pattern 2	0.6	0.7	2.7	0.5	-0.3	-0.3	-0.2	-1.6	-1.6	-0.6	0.8	0.5	1.0	0.2	-0.6
Had menopause	3.5	4.4	11.4	3.4	2.4	2.5	2.6	-0.7	-0.4	-0.2	2.4	1.3	1.0	3.0	-2.1
Had other major operations	0.3	0.3	1.9	-1.4	-0.3	-0.3	-0.1	-0.3	-0.4	0.7	-0.3	0.5	-0.3	0.1	0.7
Forced vital capacity (FVC)	0.9	3.5	8.5	-2.4	-2.1	-2.2	-1.8	-1.4	-1.5	-1.6	-1.2	-2.9	0.2	-2.1	1.7
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.7	6.9	1.3	2.6	2.5	2.5	1.7	2.0	0.1	2.2	2.1	-0.2	2.3	-1.6
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.3	0.5	0.1	-0.0	0.3	0.6	0.5	0.3	0.1	-0.3	-0.2	0.3	0.2
Qualifications: None of the above	0.1	0.2	0.6	-0.6	-0.6	-0.3	-0.3	0.1	-0.0	-0.3	-0.6	0.6	-0.0	-0.8	0.5
Financial difficulties in last 2 years	0.2	0.3	0.8	-0.8	-0.4	-0.1	-0.1	-0.1	-0.2	-0.1	-0.7	0.9	-0.8	0.5	0.6
Mouth/teeth dental problems	2.8	4.4	8.3	1.6	2.1	2.0	2.4	-1.1	-0.8	-1.8	2.3	1.7	2.5	2.7	-2.9
Heart attack	0.7	0.8	1.8	1.2	1.0	0.9	1.1	1.3	1.3	0.7	0.3	0.6	-0.8	0.5	-0.5
Allergy	0.3	0.6	2.1	0.4	-0.6	-0.8	-0.3	-1.2	-1.1	-1.0	-0.4	-1.4	-0.4	-0.6	0.2
Pain all over the body in last month	0.1	0.1	0.9	1.0	0.1	0.0	0.2	0.1	0.1	-0.4	-0.6	-0.1	0.1	-0.2	-0.4
Diabetes (self-reported)	1.1	1.7	6.7	0.6	1.3	1.4	1.7	1.6	1.6	-0.2	-0.1	2.6	-0.1	1.5	0.1
Hayfever/allergic rhinitis (self-reported)	2.2	2.9	8.6	0.1	1.9	1.9	1.6	1.9	2.0	2.9	1.2	2.2	-1.0	1.4	0.1
Medication: Ramipril	1.1	1.4	3.0	-0.8	-1.6	-1.5	-1.4	-0.1	-0.2	0.4	-1.4	-1.7	-1.1	-1.1	1.2
Medication: Simvastatin	0.3	0.4	0.9	-0.7	-0.2	-0.2	0.0	0.8	0.8	0.5	-0.9	0.5	-0.7	-0.1	0.9
Fluid intelligence score	0.9	1.9	7.4	1.7	1.8	1.7	1.7	-0.4	-0.3	0.4	2.7	1.0	-0.4	1.5	0.2
Illnesses of siblings	0.6	0.8	2.2	0.9	1.1	0.9	1.1	-0.5	-0.3	-0.7	1.1	1.5	0.5	1.1	-0.6
Neuroticism score	0.8	1.7	5.0	-0.7	-1.3	-1.3	-0.7	-2.2	-2.2	-1.7	-0.9	-1.5	-0.3	-0.3	0.6
Weight	0.4	2.0	6.8	-2.1	-1.6	-1.5	-1.7	-0.1	-0.3	0.5	-0.4	-0.3	-1.9	-1.0	2.6
Impedance of arm (right)	0.1	0.6	3.3	-0.1	0.3	0.3	0.4	0.1	0.1	-1.1	-0.0	-0.5	1.8	-0.7	-1.1
Arm fat percentage (right)	0.3	1.1	3.4	-1.8	-0.7	-0.4	-0.7	1.2	1.0	0.8	-1.1	1.0	-1.5	-0.2	1.1
Trunk fat-free mass	0.4	2.1	7.2	-1.4	-1.5	-1.7	-1.9	-0.7	-0.8	-0.1	0.4	-1.2	-1.9	-1.1	2.7
Hip circumference	0.5	2.0	8.1	-2.0	-0.6	-0.4	-1.0	0.4	0.2	1.1	0.6	1.1	-2.9	-0.1	2.8
Time employed in main current job	3.5	4.0	10.9	-0.6	-1.7	-1.7	-1.0	-2.8	-2.9	-2.8	-0.7	-1.4	3.3	-0.9	-1.8
Alcohol intake versus 10 years previously	2.4	3.6	9.1	3.0	2.2	2.4	2.5	0.7	0.9	0.5	1.2	1.9	1.0	2.0	-2.3
Father’s age at death	0.3	0.4	1.4	-1.2	-0.7	-0.8	-0.7	-0.2	-0.2	0.0	0.0	-1.2	-0.4	-0.3	0.6
Worrier / anxious feelings	0.3	0.6	2.0	-0.2	-0.4	-0.2	0.2	-1.4	-1.4	-0.2	-1.4	-0.7	-0.4	-0.2	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.1	-1.0	0.1	0.1	0.1	0.8	0.8	-0.6	-0.4	0.3	-0.4	0.1	0.2
Falls in the last year	2.1	2.8	5.5	1.1	1.9	2.0	2.0	2.3	2.3	-0.1	0.8	2.0	-0.2	2.3	-0.9
Hair/balding pattern: Pattern 3	0.4	0.6	2.1	-0.4	0.1	0.4	0.4	-0.3	-0.2	-0.6	-1.4	0.7	1.4	-0.1	-1.5
Number of live births	1.1	1.5	5.6	-0.0	-1.6	-1.3	-1.5	-0.6	-0.8	-2.4	-1.7	-1.1	0.6	-0.8	-0.1
Forced expiratory volume in 1-second (FEV1)	1.8	6.2	13.1	-3.6	-3.0	-3.0	-2.7	-1.0	-1.2	-0.4	-2.9	-3.5	-0.9	-2.6	2.3
Pulse rate	2.0	3.3	12.8	2.8	1.0	1.0	1.1	-1.1	-0.9	-1.9	1.0	0.7	3.6	1.0	-2.9
Happiness	1.4	1.7	4.5	1.5	0.8	0.6	1.2	-0.8	-0.6	-1.8	0.3	0.9	1.9	1.6	-2.1
Noisy workplace	0.4	0.5	1.4	-1.2	-0.4	-0.1	-0.1	0.5	0.3	-0.9	0.2	1.1	-0.9	0.9	1.1
Qualifications: A levels/AS levels or equivalent	0.7	1.5	4.4	0.7	1.6	1.2	1.3	1.1	1.3	1.2	2.1	0.5	0.5	1.2	-0.7
Serious illness, injury or assault of a close relative in last 2 years	4.2	4.8	8.3	2.5	2.7	2.9	2.4	1.8	2.0	1.0	1.7	2.6	0.6	2.7	-2.1
Mouth/teeth dental problems: Dentures	0.8	1.4	4.2	-0.9	-0.8	-0.6	-0.8	0.4	0.3	0.8	-2.1	-0.9	-1.6	-1.9	1.5
Asthma	1.0	2.0	5.1	1.4	1.5	1.7	1.5	-0.3	-0.2	0.3	1.2	2.3	0.9	1.6	-2.0
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	5.3	-0.2	-1.2	-1.2	-1.0	-0.4	-0.4	-1.7	-1.1	-1.5	2.3	-1.3	-0.9
Medication: Cholesterol lowering	0.4	0.7	2.4	-0.9	-0.7	-0.8	-0.5	0.8	0.8	0.5	-1.6	-1.0	-0.1	-1.1	0.3
Depression (self-reported)	0.9	1.1	5.3	1.0	0.2	0.3	0.2	-0.6	-0.5	-1.1	-0.2	0.3	2.1	0.4	-2.3
Medication: Lansoprazole	0.6	0.6	2.0	1.1	0.5	0.6	0.8	-0.2	-0.2	0.3	1.0	1.1	-0.8	1.4	0.6
Prospective memory result	0.2	0.2	1.1	0.8	0.3	0.3	0.1	0.2	0.2	-0.4	0.6	0.0	0.4	0.5	-1.0
Lung cancer (father)	1.2	1.4	4.7	1.1	0.9	1.0	0.9	0.0	0.1	-1.0	0.1	2.2	1.4	1.2	-2.0
Illnesses of mother	0.5	0.6	2.0	1.0	0.1	-0.0	0.3	-1.4	-1.3	-1.3	0.9	-0.0	0.1	0.0	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.3	9.3	-3.1	-2.7	-2.8	-2.6	-1.1	-1.2	-0.1	-1.9	-3.0	-1.3	-2.7	2.8
Pulse wave Arterial Stiffness index	1.0	1.2	2.4	-1.2	-1.4	-1.5	-1.4	0.9	0.7	-0.5	-1.5	-0.8	0.1	-0.8	1.0
Impedance of arm (left)	0.2	0.8	4.2	0.3	0.8	0.9	0.9	0.5	0.5	-0.7	0.3	-0.1	2.0	-0.2	-1.4
Arm fat mass (right)	0.4	1.6	4.8	-2.0	-0.9	-0.7	-1.1	1.1	0.8	0.9	-0.8	0.8	-2.2	-0.4	2.1
Trunk predicted mass	0.3	2.0	6.6	-1.4	-1.5	-1.7	-1.8	-0.6	-0.8	-0.2	0.3	-1.1	-1.8	-1.0	2.6
Standing height	0.3	3.2	8.7	-1.2	-1.6	-1.9	-1.8	-1.7	-1.7	-1.0	1.1	-3.0	0.0	-2.1	2.5
Length of working week for main job	0.9	1.0	3.1	-1.1	-1.1	-1.0	-0.7	-0.1	-0.2	-1.8	-1.6	-0.4	1.3	-0.7	-0.2
Exposure to tobacco smoke at home	1.9	2.1	10.2	-0.5	0.7	0.8	0.1	1.1	1.0	0.3	0.8	1.7	-3.2	0.3	2.8
Breastfed as a baby	1.2	1.4	4.5	-0.1	1.1	1.2	0.9	2.1	2.1	1.2	0.9	1.3	-0.6	0.8	-0.1
Tense / ‘highly strung’	0.7	1.2	2.1	-0.9	-1.1	-1.0	-0.7	-1.2	-1.3	-0.1	-1.2	-1.5	-1.2	-1.1	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.5	0.5	-0.6	-0.7	-0.6	-0.4	-0.4	-0.7	0.3	-0.5	0.7	0.0	-0.5
Hair/balding pattern: Pattern 4	0.2	0.5	2.0	-0.3	0.0	-0.0	0.1	0.4	0.5	-0.9	-0.6	-0.5	1.4	0.2	-1.4
Birth weight of first child	0.8	1.4	4.5	0.8	-0.7	-0.8	-0.1	-2.0	-2.0	-2.1	0.0	-1.2	0.7	-0.7	0.3
Peak expiratory flow (PEF)	0.5	1.2	3.6	-1.4	0.3	0.3	0.3	1.2	1.2	1.7	-0.5	0.4	-1.9	0.6	1.3
Pulse wave reflection index	1.2	1.5	3.8	-1.8	-1.2	-1.1	-1.2	0.7	0.5	0.4	-1.5	-0.5	-1.9	-0.6	2.0
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.3	-0.2	-0.4	-0.4	-0.1	0.7	0.5	-1.2	-0.0	-0.1	0.3	0.3	0.1
Loud music exposure frequency	0.7	0.8	2.7	-0.1	0.5	0.7	0.6	-0.6	-0.6	0.5	1.2	1.6	-1.0	1.3	0.5
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.0	0.2	0.6	0.4	0.3	0.9	1.0	0.9	0.7	-0.2	-0.7	0.5	0.6
Mouth/teeth dental problems: Bleeding gums	3.3	4.3	8.0	-2.4	-2.8	-2.8	-2.7	-0.2	-0.4	0.5	-2.7	-2.1	-0.7	-2.6	1.9
Blood clot in the leg (DVT)	0.4	0.6	1.6	0.2	0.7	0.7	0.4	1.0	1.0	1.3	0.1	1.1	-0.7	0.5	-0.3
Medication: Paracetamol	0.9	1.6	2.5	1.3	1.3	1.5	1.1	1.5	1.6	1.0	0.1	1.6	0.2	1.4	-1.4
Headache pain in last month	0.5	0.8	2.2	0.3	0.3	0.6	0.7	0.4	0.4	-0.6	-0.7	1.4	1.5	1.1	-1.4
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	4.0	0.7	0.4	0.3	0.3	-1.2	-1.1	-1.2	2.0	0.6	-0.7	0.5	0.8
Glaucoma (self-reported)	0.8	0.9	3.4	-1.9	-1.0	-0.8	-0.7	-0.3	-0.4	-0.7	-1.6	0.1	-0.1	-1.0	1.1
Gout (self-reported)	0.6	0.9	2.3	-0.2	0.5	0.6	0.9	-0.3	-0.3	-1.5	0.6	1.2	1.5	1.3	-0.9
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	6.0	-1.1	-0.1	0.1	-0.1	0.8	0.6	1.3	-0.2	1.0	-2.4	-0.3	2.0
Medication: Amlodipine	1.1	1.5	5.7	1.0	-0.2	-0.4	-0.2	-1.0	-0.8	-1.3	-0.6	-1.0	2.4	-0.8	-2.3
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.2	0.9	0.6	0.6	0.5	0.4	0.5	0.2	0.0	1.1	-0.1	0.8	-1.0
Birth weight	0.5	1.1	6.6	-0.5	-1.0	-0.9	-0.6	-0.0	-0.2	-0.2	0.0	-1.1	-1.5	-1.0	2.6
Chronic bronchitis/emphysema (mother)	1.4	1.6	2.9	-1.2	-1.5	-1.5	-1.3	-0.6	-0.7	-1.6	-1.7	-1.3	1.6	-1.1	-0.7
High blood pressure (siblings)	0.8	1.2	3.5	-1.8	-1.1	-0.8	-1.2	0.6	0.5	1.0	-1.9	-1.1	-0.5	-0.8	0.6
Forced vital capacity (FVC), Best measure	1.0	3.8	8.4	-2.1	-2.2	-2.3	-2.1	-1.4	-1.5	-1.1	-0.9	-2.9	-0.6	-2.6	2.5
Body fat percentage	0.4	1.7	5.6	-2.4	-0.8	-0.4	-0.9	1.3	1.0	1.5	-1.3	1.1	-1.6	-0.5	1.5
Leg fat percentage (right)	0.6	2.3	8.7	-3.0	-1.3	-0.9	-1.3	1.3	0.9	1.6	-2.1	1.0	-1.5	-0.7	1.2
Arm fat-free mass (right)	0.4	1.9	8.6	-1.4	-1.2	-1.2	-1.5	-0.2	-0.3	0.9	0.5	-0.5	-2.4	-0.5	2.9
Exposure to tobacco smoke outside home	0.5	0.6	2.6	-1.6	-0.9	-0.8	-0.5	0.6	0.5	-0.2	-1.6	-0.1	-0.4	-0.4	0.4
Comparative body size at age 10	0.5	1.4	5.5	-0.8	0.0	0.2	-0.3	1.5	1.4	1.4	-0.6	1.0	-2.4	0.3	1.8
Number of full brothers	0.5	0.6	1.4	0.7	-0.4	-0.5	-0.4	-0.9	-0.8	-0.8	-0.9	-0.4	1.2	-0.8	-1.1
Worry too long after embarrassment	1.8	3.0	6.9	-0.8	-1.7	-1.8	-1.7	-1.8	-1.9	0.8	-0.2	-2.6	-1.9	-1.3	2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.9	-0.5	-0.7	-0.6	-0.6	-0.4	-0.4	-0.7	-0.9	0.9	1.0	0.6	-0.5
Wheeze or whistling in the chest in last year	2.6	4.6	16.1	1.9	2.2	2.6	2.7	0.4	0.5	0.9	0.8	4.0	0.6	2.9	-2.5
Number of children fathered	0.3	0.4	3.4	-0.7	-0.3	-0.3	0.1	-0.0	0.1	-0.2	-1.9	-0.2	0.2	-0.0	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	1.9	2.2	5.2	-0.1	-1.4	-1.4	-1.2	-2.2	-2.2	-1.5	-0.9	-2.3	1.0	-1.1	-0.7
Age at first live birth	0.1	0.3	1.2	0.0	-0.2	-0.4	-0.2	-0.5	-0.4	-0.7	0.1	-1.1	0.5	-0.7	-0.2
Pulse wave peak to peak time	1.0	1.1	2.4	1.2	1.4	1.4	1.4	-1.0	-0.7	0.4	1.6	0.7	0.0	0.8	-1.0
Health satisfaction	0.6	0.8	3.0	-0.0	0.6	0.5	1.2	-0.4	-0.4	-0.7	-0.1	1.1	1.1	1.7	-1.0
Shortness of breath walking on level ground	0.8	0.9	4.5	0.6	1.2	1.1	1.0	-0.4	-0.3	-0.2	2.1	0.8	0.3	1.2	-0.5
Qualifications: College or University degree	0.9	2.9	13.4	2.1	1.7	1.1	1.4	-1.3	-0.9	-0.7	3.7	-0.4	1.7	1.5	-1.7
Eye problems/disorders: None of the above	2.2	2.5	8.2	-2.5	-1.6	-1.6	-1.7	-0.1	-0.2	0.5	-1.0	-1.2	-1.7	-1.6	2.9
Mouth/teeth dental problems: Loose teeth	0.4	0.5	2.0	-0.5	-0.9	-0.7	-0.9	0.2	0.1	0.5	-1.4	-0.3	-0.2	-0.6	0.5
Emphysema/chronic bronchitis	0.2	0.2	1.0	-0.8	-0.0	0.2	0.1	0.5	0.4	0.5	-1.0	0.6	-0.1	0.5	0.1
Medication for pain relief, constipation, heartburn	0.7	1.2	3.2	-0.9	-0.6	-0.7	-0.2	-1.8	-1.8	-1.6	-0.1	-1.0	1.3	-0.4	-0.6
Neck or shoulder pain in last month	0.8	1.1	5.2	-0.2	0.1	0.3	0.5	-0.4	-0.4	-1.3	-0.9	1.0	1.9	0.6	-2.3
Medication: Blood pressure	0.6	1.1	4.5	-0.6	-0.8	-0.6	-0.8	0.8	0.8	0.8	-2.1	-1.0	1.4	-0.9	-1.3
Angina (self-reported)	0.2	0.3	0.9	-0.4	0.5	0.6	0.7	0.1	0.1	0.8	-0.2	1.0	0.1	0.4	-0.7
Migraine (self-reported)	1.5	1.9	4.6	-2.0	-1.8	-1.6	-1.7	0.3	0.0	0.2	-2.2	-0.8	-1.0	-0.9	1.6
Medication: Ibuprofen	1.6	1.9	9.4	0.1	-0.8	-0.8	-0.5	-0.4	-0.5	-1.9	-1.1	-1.2	3.1	-0.6	-2.1
Medication: Allopurinol	0.8	1.1	2.3	-0.0	1.1	1.2	1.3	0.3	0.4	-0.6	0.6	1.5	1.5	1.1	-1.3
Medication: Omeprazole	0.7	0.8	4.0	-0.2	-0.0	0.1	-0.0	0.4	0.4	2.0	-0.5	0.3	-2.0	-0.1	1.1
Medication: Seretide 50 evohaler	3.2	3.7	7.5	2.2	2.5	2.5	2.1	0.7	0.8	0.2	2.3	2.7	1.0	1.7	-2.1
Mean time to correctly identify matches	1.4	2.7	8.5	0.3	-1.6	-1.5	-1.2	-2.9	-2.9	-1.1	-0.4	-1.9	1.5	-1.4	0.2
Heart disease (mother)	0.8	1.0	3.1	-0.7	0.4	0.4	0.1	1.3	1.2	1.8	1.0	0.4	-1.4	0.3	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	2.5	-0.3	0.8	1.1	1.2	1.1	1.0	0.6	-0.9	1.6	0.2	1.0	-0.7
Whole body fat mass	0.5	2.0	6.5	-2.5	-1.3	-1.0	-1.4	0.8	0.5	1.3	-1.0	0.5	-2.1	-0.7	2.2
Leg fat mass (right)	0.6	2.2	8.1	-2.8	-1.6	-1.3	-1.7	0.7	0.4	1.0	-1.4	0.4	-1.8	-0.8	1.9
Arm predicted mass (right)	0.4	1.9	8.8	-1.4	-1.2	-1.3	-1.5	-0.5	-0.6	0.6	0.7	-0.6	-2.3	-0.5	3.0
Pulse rate, automated reading	2.4	7.6	36.6	3.2	0.4	0.4	0.9	-2.2	-2.0	-3.2	0.2	-0.3	6.0	0.7	-4.8
Alcohol intake frequency.	1.2	2.8	5.6	2.4	2.0	2.2	2.2	-0.6	-0.4	-1.0	1.5	1.9	0.6	1.9	-1.8
Comparative height size at age 10	0.3	1.5	8.6	1.2	1.3	1.1	0.9	0.3	0.4	-0.8	2.9	0.3	-1.1	0.5	1.4
Number of full sisters	2.0	2.4	4.3	1.9	2.1	2.0	1.6	1.2	1.4	0.5	0.9	1.4	1.4	1.3	-2.0
Suffer from ‘nerves’	0.6	1.0	4.1	-0.8	-1.2	-0.8	-0.8	0.2	-0.0	0.6	-2.0	0.2	-1.2	-0.4	1.6
Overall health rating	0.8	1.7	6.5	-1.0	-1.3	-1.0	-0.3	-1.5	-1.6	-2.6	-1.7	0.5	1.3	-0.1	-0.4
Chest pain or discomfort	0.7	1.0	2.9	-0.5	1.0	1.2	1.5	0.8	0.8	0.0	-0.5	1.3	-0.3	1.7	-0.6
Had major operations	1.4	1.6	6.0	-1.4	-1.0	-1.0	-0.9	1.9	1.7	0.5	-2.5	0.2	1.0	-0.4	-0.7
Age at last live birth	0.9	1.3	3.7	-0.1	-1.3	-1.4	-1.3	-1.0	-1.0	-1.9	-0.7	-1.3	1.3	-0.8	-0.3
Family relationship satisfaction	2.0	2.5	4.9	-0.6	-2.1	-2.2	-1.8	-1.3	-1.5	-1.6	-1.7	-1.9	0.1	-1.4	1.5
Leg pain on walking	1.2	1.5	3.3	-1.8	-1.5	-1.3	-1.3	-1.5	-1.7	-0.8	-0.6	0.6	0.1	-0.8	1.6
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	3.5	-1.1	-1.4	-1.3	-1.5	1.1	0.9	1.2	-1.9	-0.9	-1.1	-1.5	1.6
Commuting to job workplace: Car/motor vehicle	0.6	0.6	2.2	-1.1	-0.6	-0.5	-0.3	-1.2	-1.2	-1.5	0.2	0.0	0.5	0.1	-0.5
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.8	-0.5	-0.3	-0.4	-0.4	-0.0	-0.0	0.1	0.2	0.2	-0.3	-0.4	0.9
Medication: Aspirin	0.4	0.5	1.1	0.8	0.5	0.5	0.5	1.0	1.0	0.5	0.3	0.7	-1.1	0.8	0.6
Supplements: Vitamin C	0.2	0.2	0.8	0.1	0.6	0.6	0.4	0.2	0.3	0.4	0.2	0.9	-0.6	0.7	-0.1
Knee pain experienced in last month	0.5	0.8	2.1	-1.2	-0.7	-0.5	-0.6	1.4	1.1	0.1	-0.2	0.8	-0.9	-0.6	1.4
Hypertension (Self-reported)	0.6	1.5	7.5	-0.4	-0.3	0.0	0.0	-0.6	-0.6	-0.7	-1.5	0.4	2.6	0.3	-2.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.4	2.8	7.1	2.0	2.0	2.0	2.0	1.1	1.2	1.1	1.6	1.6	0.3	2.7	-1.4
Illnesses of father: Heart disease	0.7	1.0	4.6	-0.5	0.1	0.3	0.2	0.1	0.0	2.2	-0.3	-0.7	-2.1	-0.7	1.1
Illnesses of siblings: Diabetes	0.7	0.9	2.1	-0.5	-1.4	-1.2	-1.2	-0.3	-0.5	-0.9	-1.4	-0.4	-0.2	-1.2	0.9
Smoking status: Previous	0.2	0.3	1.1	-0.2	-0.5	-0.7	-0.3	0.4	0.5	0.1	-1.0	-0.6	0.7	-0.2	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.5	0.2	0.5	0.4	0.7	-0.3	-0.2	0.0	0.6	-0.1	0.1	0.1	0.1
Whole body fat-free mass	0.4	2.1	8.5	-1.4	-1.4	-1.6	-1.7	-0.6	-0.7	-0.2	0.6	-1.0	-2.0	-0.9	2.9
Leg fat-free mass (right)	0.3	1.8	8.3	-1.1	-1.2	-1.3	-1.3	-0.8	-0.9	-0.6	0.9	-0.8	-1.9	-0.4	2.9
Arm fat percentage (left)	0.3	1.2	3.4	-1.8	-0.5	-0.2	-0.6	1.4	1.2	1.1	-1.0	1.2	-1.5	0.0	1.2
Average weekly red wine intake	1.5	2.2	5.3	-1.9	-1.4	-1.6	-1.6	0.3	0.2	0.5	-2.1	-1.2	-1.5	-1.6	2.3
Handedness (chirality/laterality): Left-handed	0.9	1.1	3.4	-0.2	-0.9	-1.1	-0.8	-1.4	-1.3	-0.3	-0.9	-1.8	-0.0	-1.6	0.0
Mood swings	0.4	0.7	3.1	-1.8	-1.0	-0.8	-0.7	0.3	0.1	-0.2	-1.2	-0.4	-0.3	-0.8	0.6
Loneliness, isolation	1.2	1.7	5.8	0.9	-0.5	-0.3	0.3	-2.4	-2.4	-2.4	-0.1	-0.4	1.4	0.3	-0.7
Long-standing illness, disability or infirmity	1.0	1.5	6.7	-0.1	1.1	1.4	1.3	1.1	1.1	0.3	0.4	2.6	-0.7	1.8	0.1
Ever had bowel cancer screening	0.8	0.9	4.6	0.1	-0.0	-0.0	0.3	-0.9	-0.9	-0.8	-0.7	-0.6	2.2	-0.0	-1.7
Diabetes diagnosed by doctor	1.0	1.6	4.8	0.1	1.0	0.9	1.2	2.2	2.2	0.6	-0.3	2.0	-0.4	1.2	0.4
Ever had stillbirth, spontaneous miscarriage or termination	2.2	2.4	6.6	2.6	1.7	1.7	1.8	-0.5	-0.3	-0.3	1.9	1.9	0.6	2.0	-0.9
Friendships satisfaction	0.9	1.1	3.2	1.4	-0.0	-0.3	-0.5	-0.5	-0.6	0.2	1.8	-0.9	-1.8	-0.2	1.7
Qualifications: nursing, teaching	0.6	0.9	2.2	1.5	1.0	0.9	0.8	0.1	0.3	0.2	1.1	0.1	1.0	1.2	-1.5
Commuting to job workplace: Walk	0.2	0.3	1.0	0.9	0.1	-0.1	-0.2	-0.4	-0.3	0.3	0.0	-1.0	0.5	0.5	-0.5
Eye problems/disorders: Cataract	0.7	0.8	2.7	1.6	0.6	0.6	0.5	-0.4	-0.4	-0.6	1.1	-0.2	1.1	0.3	-1.6
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.6	0.4	-1.1	-1.1	-1.3	-0.5	-0.6	-0.8	-0.5	-1.2	0.5	-0.7	-0.0
Medication for cholesterol	0.1	0.1	0.6	0.4	0.2	0.1	-0.0	-0.2	-0.2	0.2	0.8	-0.4	-0.2	0.3	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	0.8	-0.5	-0.4	-0.4	-0.6	0.9	0.7	0.9	-0.5	-0.1	-0.7	-0.5	0.9
Back pain experienced in last month	0.3	0.5	1.4	-1.1	-0.3	-0.0	-0.2	-0.6	-0.7	0.3	0.3	0.8	-1.2	0.9	0.7
Mineral and other dietary supplements	1.5	2.0	4.8	1.3	-0.2	-0.5	-0.3	-2.2	-2.1	-2.0	2.1	-0.6	1.8	-0.6	-0.5
Breast cancer (self-reported)	2.2	2.7	6.5	-1.9	-2.1	-2.1	-1.6	-1.8	-1.9	-0.7	-2.5	-1.3	0.6	-1.2	0.4
Asthma (self-reported)	0.9	1.9	5.6	1.2	1.4	1.7	1.5	-0.6	-0.5	0.4	1.2	2.4	0.8	1.5	-1.8
Osteoporosis (self-reported)	0.3	0.4	1.2	0.2	0.9	1.1	1.1	0.2	0.3	0.6	0.3	0.7	-0.2	0.6	0.0
Osteoarthritis (self-reported)	0.5	0.7	3.2	-0.8	-0.5	-0.4	-0.1	-0.1	-0.2	-1.2	-0.6	1.0	1.8	0.4	-0.8
Medication: Aspirin	0.5	0.6	1.5	1.0	0.8	0.7	0.7	1.2	1.2	0.2	0.3	0.6	-0.8	0.9	0.4
Medication: Gliclazide	0.4	0.4	1.0	-0.6	-0.9	-1.0	-1.0	0.3	0.2	0.3	-0.7	-0.3	-0.1	-0.5	0.8
Illnesses of father: None of the above (group 1)	1.4	1.7	8.1	1.1	-0.0	-0.1	0.1	-0.4	-0.3	-2.8	0.4	0.6	2.6	0.6	-1.8
Smoking status: Current	0.6	1.0	3.7	-0.5	-0.2	0.1	-0.1	1.5	1.3	-0.6	-1.9	1.5	0.5	0.7	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	2.0	4.3	-2.1	-1.7	-1.6	-1.6	-0.5	-0.6	0.0	-1.5	-1.5	-1.4	-1.3	1.7
Whole body water mass	0.3	1.9	8.0	-1.3	-1.3	-1.5	-1.6	-0.5	-0.6	-0.1	0.6	-0.9	-2.0	-0.8	2.8
Leg predicted mass (right)	0.3	1.8	8.4	-1.1	-1.2	-1.3	-1.3	-0.8	-0.9	-0.6	0.9	-0.8	-1.9	-0.4	2.9
Arm fat mass (left)	0.3	1.4	3.8	-1.9	-1.1	-0.9	-1.2	0.7	0.5	0.8	-0.7	0.4	-1.9	-0.5	2.0
Number of self-reported non-cancer illnesses	0.7	1.2	4.3	-0.2	0.4	0.7	0.1	2.1	1.9	1.1	-1.1	1.7	-0.5	0.6	0.2
Average weekly champagne plus white wine intake	0.4	0.5	1.4	-0.4	-0.3	-0.8	-0.5	-0.9	-0.8	0.0	1.2	-1.2	-0.1	-0.4	0.8
Miserableness	1.0	1.7	3.6	-0.9	-1.6	-1.6	-1.1	-1.8	-1.9	-1.7	-1.1	-1.5	0.2	-0.6	0.1
Guilty feelings	0.6	0.9	4.1	0.1	-0.6	-0.5	-0.2	-2.0	-2.0	-0.4	-0.1	-0.9	-0.5	-0.0	0.5
Wears glasses or contact lenses	0.8	0.9	2.9	0.5	0.6	0.6	0.5	1.6	1.6	1.7	-0.1	0.6	-1.1	0.4	0.4
Ever taken oral contraceptive pill	0.2	0.3	0.7	0.3	0.6	0.6	0.5	0.7	0.8	-0.4	-0.6	0.1	0.3	-0.1	-0.5
Hearing aid user	1.7	1.9	5.6	1.8	1.6	1.5	1.4	0.6	0.7	1.0	2.4	1.4	-1.1	1.5	0.3
Mother’s age at death	2.2	2.7	5.5	-2.2	-1.9	-2.0	-2.4	0.7	0.5	1.1	-1.5	-2.1	-0.7	-2.0	1.2
Financial situation satisfaction	1.2	1.5	3.1	-1.5	-0.2	-0.1	-0.3	1.8	1.5	1.1	-1.0	1.5	-1.7	-0.0	1.6
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.9	0.4	0.3	0.1	0.5	0.3	0.4	0.4	0.9	-0.1	-0.8	-0.2	0.7
Commuting to job workplace: Public transport	0.1	0.1	0.4	0.1	0.3	0.2	0.6	0.0	0.1	-0.1	-0.2	-0.2	0.4	0.3	-0.0
Eye problems/disorders: Glaucoma	0.3	0.3	1.1	-0.5	-0.3	-0.2	-0.1	0.5	0.5	-0.4	-1.1	0.5	-0.5	-0.4	0.9
Medication: Blood pressure	0.4	0.8	2.4	0.5	-0.0	0.2	0.4	-1.5	-1.5	-1.5	-0.1	0.4	1.0	0.3	-0.9
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.2	-0.2	-0.0	-0.1	0.3	-0.7	-0.7	-0.6	0.3	0.1	1.1	0.9	-0.7
Supplements: Fish oil (including cod liver oil)	1.0	1.3	5.4	-0.7	-0.2	0.1	-0.2	0.9	0.9	1.7	-2.0	0.2	-2.3	-0.2	1.1
High cholesterol (Self-reported)	0.3	0.5	1.8	-1.0	-0.2	-0.1	-0.2	0.9	0.8	0.6	-1.3	0.3	-0.7	-1.0	0.6
Medication: Bendroflumethiazide	0.7	1.1	4.1	0.1	-0.7	-0.5	-0.7	-0.1	-0.1	-0.3	-1.7	-1.0	1.9	-0.8	-2.0
Medication: Paracetamol	1.1	1.7	3.9	1.1	1.2	1.5	1.3	1.3	1.4	0.7	-0.1	1.7	0.8	1.4	-2.0
Medication: Lisinopril	0.2	0.3	0.9	-0.3	0.1	0.0	0.1	0.1	0.1	-0.9	0.1	-0.3	0.9	-0.6	-0.9
Medication: Atorvastatin	0.1	0.1	0.6	0.3	0.2	0.1	0.4	-0.1	-0.0	0.4	-0.8	-0.2	0.1	-0.4	-0.1
Illnesses of father: High blood pressure	0.5	0.6	1.7	-1.3	-0.8	-0.6	-0.8	-0.4	-0.5	0.3	-1.3	-0.9	-0.4	-0.7	-0.0
Alcohol drinker status: Never	3.9	4.7	10.9	1.5	2.9	3.1	2.8	1.5	1.6	0.5	2.4	3.3	-0.4	2.2	-1.3
Ever smoked	1.5	2.7	9.7	-2.1	-1.8	-1.8	-1.8	1.7	1.5	-0.0	-3.1	-1.0	0.5	-1.3	0.2
Basal metabolic rate	0.4	2.0	8.6	-1.5	-1.4	-1.5	-1.7	-0.4	-0.5	0.0	0.4	-0.7	-2.1	-0.9	2.9
Leg fat percentage (left)	0.6	2.0	7.9	-2.8	-1.1	-0.6	-1.1	1.1	0.8	1.7	-1.7	1.3	-1.7	-0.4	1.3
Arm fat-free mass (left)	0.4	2.0	7.2	-1.3	-1.6	-1.7	-1.8	-0.7	-0.9	0.0	0.4	-0.9	-1.9	-1.0	2.7
Number of operations (self-reported)	1.9	2.9	11.2	-3.3	-2.2	-2.1	-1.9	0.6	0.2	0.1	-2.8	-0.6	0.5	-0.9	0.6
Average weekly beer plus cider intake	0.2	0.3	1.6	-0.5	0.1	0.3	0.1	0.3	0.2	1.3	-0.4	-0.0	-0.9	0.1	0.5
Irritability	0.3	0.6	3.2	-1.8	-0.6	-0.6	-0.8	-0.1	-0.2	0.1	0.3	-0.6	-0.8	-0.7	0.9
Risk taking	0.3	0.5	2.7	0.1	0.8	0.7	0.8	0.3	0.5	-0.1	0.2	0.4	0.8	0.6	-1.6
Ever had prostate specific antigen (PSA) test	1.4	1.6	4.1	-0.5	-1.2	-1.3	-1.3	-0.0	-0.0	-1.2	-2.0	-1.8	1.4	-1.9	-0.7
Fractured/broken bones in last 5 years	2.6	3.4	8.2	1.9	2.2	2.2	2.4	0.9	1.0	0.3	1.7	2.7	0.2	2.9	-1.3
Age started oral contraceptive pill	0.5	0.7	3.6	0.9	0.8	0.6	0.8	-0.7	-0.6	0.2	1.9	-0.5	0.1	0.7	-0.5
Diastolic blood pressure, automated reading	0.4	1.3	7.0	-0.3	0.1	0.6	0.7	-0.3	-0.3	0.6	-1.2	1.0	2.1	0.6	-2.6
Ever depressed for a whole week	0.2	0.3	2.1	1.4	0.2	0.1	0.1	-0.3	-0.2	0.1	0.7	-0.2	-0.1	0.3	-0.5
Unable to work because of sickness or disability	0.3	0.4	1.3	0.7	0.1	0.2	0.0	0.9	0.8	0.5	-0.8	1.1	-0.3	0.9	0.3
Commuting to job workplace: Cycle	1.1	1.3	4.1	2.0	1.5	1.7	1.5	-0.2	0.0	0.5	0.5	1.2	-0.5	1.1	-0.8
Myopia	1.8	2.7	7.7	-2.6	-1.9	-1.8	-1.2	0.2	-0.1	0.1	-2.8	-1.1	-0.8	-1.8	2.1
Vascular/heart problems diagnosed by doctor	0.7	1.8	6.8	0.6	0.9	0.6	0.6	1.1	1.2	1.4	1.6	0.0	-2.6	-0.1	2.5
Cholesterol lowering medication	0.4	0.6	2.2	0.6	0.8	0.8	0.7	0.1	0.1	0.5	0.5	1.5	-1.1	0.7	0.7
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	4.2	-0.0	-0.0	0.1	0.1	0.3	0.3	2.0	-0.7	0.3	-2.1	0.3	1.2
Pain experienced in last month	0.4	0.6	2.2	-0.4	-0.4	-0.5	-0.8	0.2	0.2	0.9	0.2	-1.5	-0.6	-1.4	1.0
Supplements: Calcium	0.4	0.4	2.1	-0.6	-0.4	-0.5	-0.5	0.7	0.8	0.1	-1.4	-0.5	0.6	0.2	-0.3
Basal cell carcinoma (self-reported)	0.1	0.1	0.7	0.4	-0.0	0.0	-0.5	0.1	0.1	0.5	0.8	0.1	-0.1	-0.3	-0.0
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.4	1.2	0.9	0.7	0.8	1.1	1.1	0.5	0.3	0.3	-0.9	0.2	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.9	0.3	0.7	0.7	0.4	0.9	0.9	1.4	0.3	1.1	-0.7	0.5	-0.2
Heart disease (siblings)	0.4	0.5	1.9	0.6	0.5	0.4	0.6	0.6	0.7	-0.0	-0.2	-0.7	1.0	0.2	-1.4
Alcohol drinker status: Previous	0.4	0.4	1.2	-0.4	0.2	0.1	0.3	0.7	0.7	0.8	0.1	-0.0	-0.9	1.0	1.1
Pack years of smoking	0.4	0.5	2.7	-0.2	0.2	0.3	0.2	1.7	1.4	-0.3	-0.6	0.9	-0.5	0.3	-0.2
Impedance of whole body	0.1	0.5	3.0	-0.1	0.5	0.7	0.6	0.4	0.4	-0.1	-0.1	0.1	1.7	-0.5	-1.2
Leg fat mass (left)	0.5	1.9	7.2	-2.7	-1.3	-1.0	-1.4	0.6	0.3	1.0	-1.1	0.7	-1.9	-0.5	1.9
Arm predicted mass (left)	0.3	1.7	7.1	-1.2	-1.2	-1.3	-1.5	-0.4	-0.5	0.3	0.5	-0.5	-2.0	-0.7	2.7