Hub : Genes

FAAH

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1730 0.0420 4.2e-10 0.019 0.084 0.089 0.090 0.081 2.0e-03 2.1e-10 5.3e-11 5.0e-11 4.7e-10
2 GTEx Adipose Subcutaneous 0.1420 0.0540 4.3e-03 0.070 NA 0.067 NA 0.072 2.2e-06 NA 3.7e-06 NA 1.7e-06
3 GTEx Artery Aorta 0.1080 0.0500 2.2e-03 0.040 NA 0.032 NA 0.066 2.8e-03 NA 7.2e-03 NA 1.7e-04
4 GTEx Artery Tibial 0.1537 0.0476 1.9e-05 0.129 NA 0.111 NA 0.136 2.6e-10 NA 5.2e-09 NA 8.7e-11
5 GTEx Brain Cerebellum 0.2340 0.0930 2.6e-03 0.150 NA 0.177 NA 0.220 3.4e-05 NA 6.4e-06 NA 3.8e-07
6 GTEx Brain Nucleus accumbens basal ganglia 0.1930 0.0840 4.3e-03 0.084 NA 0.058 NA 0.080 2.9e-03 NA 1.2e-02 NA 3.6e-03
7 GTEx Cells EBV-transformed lymphocytes 0.4080 0.1090 1.9e-04 0.113 NA 0.119 NA 0.128 1.6e-04 NA 1.1e-04 NA 5.8e-05
8 GTEx Cells Transformed fibroblasts 0.2030 0.0630 4.2e-06 0.056 NA 0.142 NA 0.116 5.0e-05 NA 8.6e-11 NA 5.3e-09
9 GTEx Colon Transverse 0.1270 0.0490 1.7e-03 0.044 NA 0.051 NA 0.066 3.8e-03 NA 1.9e-03 NA 4.6e-04
10 GTEx Esophagus Mucosa 0.1230 0.0390 5.0e-06 0.082 NA 0.060 NA 0.069 4.1e-06 NA 7.1e-05 NA 2.2e-05
11 GTEx Esophagus Muscularis 0.1100 0.0410 1.1e-04 0.105 NA 0.064 NA 0.089 6.1e-07 NA 1.0e-04 NA 4.5e-06
12 GTEx Heart Left Ventricle 0.1241 0.0600 5.9e-03 0.033 NA 0.011 NA 0.026 7.2e-03 NA 8.2e-02 NA 1.5e-02
13 GTEx Muscle Skeletal 0.0952 0.0341 6.0e-04 0.001 NA 0.001 NA -0.003 2.7e-01 NA 2.4e-01 NA 8.7e-01
14 GTEx Skin Not Sun Exposed Suprapubic 0.1360 0.0540 3.9e-04 0.037 NA 0.042 NA 0.044 4.2e-03 NA 2.4e-03 NA 1.8e-03
15 GTEx Skin Sun Exposed Lower leg 0.3050 0.0680 6.3e-10 0.065 NA 0.139 NA 0.104 4.6e-06 NA 1.5e-11 NA 5.9e-09
16 GTEx Stomach 0.1830 0.0670 1.2e-03 0.012 NA -0.003 NA 0.005 8.6e-02 NA 5.2e-01 NA 1.8e-01
17 GTEx Testis 0.1470 0.0540 1.5e-03 0.149 NA 0.112 NA 0.123 4.0e-07 NA 1.1e-05 NA 4.1e-06
18 GTEx Thyroid 0.1630 0.0520 7.5e-05 0.062 NA 0.055 NA 0.076 1.8e-05 NA 4.8e-05 NA 1.9e-06
19 GTEx Whole Blood 0.0970 0.0550 6.4e-03 -0.001 NA 0.008 NA -0.001 4.8e-01 NA 5.8e-02 NA 4.1e-01
20 ROSMAP Brain Pre-frontal Cortex 0.2157 0.0458 1.1e-16 0.149 0.145 0.180 0.177 0.176 1.1e-18 3.1e-18 1.3e-22 3.7e-22 4.8e-22
21 YFS Blood 0.1147 0.0295 0.0e+00 0.084 0.124 0.132 0.125 0.128 5.0e-26 1.8e-38 5.4e-41 9.1e-39 1.3e-39
22 TCGA Breast Invasive Carcinoma 0.0430 0.0176 1.1e-07 0.019 0.040 0.028 NA 0.030 6.4e-05 1.3e-08 1.4e-06 NA 8.0e-07
23 TCGA Colon Adenocarcinoma 0.1210 0.0460 1.2e-09 0.179 0.174 0.177 NA 0.174 1.4e-10 2.7e-10 1.8e-10 NA 2.6e-10
24 TCGA Kidney Renal Clear Cell Carcinoma 0.0418 0.0206 2.3e-05 0.051 0.045 0.038 NA 0.045 1.7e-06 7.4e-06 3.7e-05 NA 8.2e-06
25 TCGA Kidney Renal Papillary Cell Carcinoma 0.1030 0.0500 1.6e-03 0.023 0.038 0.006 NA 0.025 1.8e-02 3.1e-03 1.3e-01 NA 1.4e-02
26 TCGA Pancreatic Adenocarcinoma 0.0780 0.0450 7.5e-03 0.070 0.049 0.028 NA 0.050 6.9e-04 4.1e-03 2.3e-02 NA 3.7e-03
27 TCGA Prostate Adenocarcinoma 0.1644 0.0520 0.0e+00 0.263 0.261 0.275 NA 0.274 2.0e-27 3.6e-27 8.1e-29 NA 1.2e-28
28 TCGA Thyroid Carcinoma 0.1080 0.0380 1.6e-13 0.150 0.143 0.141 NA 0.151 1.8e-14 8.8e-14 1.2e-13 NA 1.7e-14

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28
Bipolar Disorder (2018) 3.9 6.1 15.0 2.7 1.1 -1.1 -1.4 2.3 0.0 -0.4 -1.6 3.9 -2.5 -2.2 -2.8 -0.0 -2.2 -1.1 0.4 -2.3 3.3 -1.1 1.3 -1.7 3.8 3.0 3.7 3.6 3.5 3.7 3.7
Bipolar Disorder or Schizophrenia 0.7 1.8 4.1 1.5 1.2 -1.0 -1.1 0.4 -0.7 -0.9 -0.3 2.0 -1.5 -1.5 -0.7 -0.4 -1.7 0.2 -0.2 -1.4 1.3 -0.4 0.1 -1.3 1.9 1.7 2.0 1.9 1.4 2.0 1.9
Depressed Affect (Nagel 2018) 0.6 1.3 3.6 0.9 0.2 -1.4 -1.2 -0.4 -1.5 -1.2 -0.6 1.2 -1.8 -1.7 -1.1 0.0 -1.9 -1.1 -0.4 -1.5 0.3 -0.4 -0.8 -1.8 1.0 1.1 1.1 0.6 0.2 1.5 1.3
Depression (Nagel 2018) 0.5 0.7 3.3 1.8 1.7 -0.5 -0.3 -0.3 -1.0 -0.5 0.6 0.6 -1.1 -1.1 -0.6 -0.3 -1.1 0.2 -0.3 -0.7 -0.1 -1.2 -0.4 -1.0 0.8 0.5 0.8 0.7 -0.1 0.9 0.7
Intelligence (Savage-Jansen 2018) 0.4 1.3 4.5 -1.9 -2.1 -1.7 -1.7 -0.4 -0.4 -1.4 -2.0 0.2 -0.1 -1.1 -1.8 -1.7 -0.3 -1.3 -1.4 -1.2 0.8 -1.0 -1.2 -0.6 -0.5 -0.0 -0.4 -0.2 0.7 0.1 0.2
Neuroticism (Nagel 2018) 0.2 0.4 1.6 0.6 0.1 -0.8 -0.4 -0.2 -1.3 -0.8 -0.8 0.5 -0.9 -1.1 -0.9 0.3 -1.1 -0.7 -0.6 -0.6 -0.1 0.2 -1.1 -0.9 0.4 0.0 0.3 0.3 -0.4 0.5 0.4
Schizophrenia (2018) 0.2 0.5 2.0 -1.1 0.7 -0.4 -0.2 -1.0 -1.0 -0.9 0.8 -0.5 0.1 -0.1 1.4 -0.3 -0.5 1.2 -0.6 0.1 -0.8 0.4 -0.9 -0.4 -0.6 -0.3 -0.3 -0.4 -0.9 -0.4 -0.4
Schizophrenia vs Biploar Disorder 2.2 3.0 9.0 -1.9 0.8 0.9 1.5 -1.7 -0.8 0.6 2.3 -2.3 1.5 1.5 3.0 -0.3 0.7 1.8 -0.7 1.8 -2.9 1.1 -1.1 0.6 -1.8 -1.7 -1.8 -1.5 -3.0 -2.1 -2.1
Worry (Nagel 2018) 0.2 0.4 1.7 0.5 -1.2 -1.0 -0.8 0.4 -0.5 -0.9 -1.1 0.3 -0.3 -0.7 -0.9 1.3 -0.3 -0.3 0.0 -0.6 0.7 0.4 -0.6 -0.3 -0.0 -0.3 -0.2 -0.0 0.4 0.1 0.0
Alzheimer’s Disease (in mother) 0.0 0.1 0.4 -0.3 0.1 0.1 0.2 0.3 -0.3 -0.1 0.1 0.1 -0.1 0.2 -0.0 -0.0 0.0 -0.0 -0.7 0.2 0.1 -0.3 -0.1 -0.1 -0.4 0.0 -0.2 -0.3 -0.0 -0.2 -0.3
Alzheimer’s Disease (in father) 1.2 1.3 4.3 0.8 0.4 -0.9 -0.8 -0.9 -1.1 -0.6 -1.5 1.0 -1.6 -1.1 -1.5 -0.7 -1.4 -2.1 0.1 -1.2 0.6 -1.7 0.2 -1.5 1.0 1.2 1.4 1.2 0.9 1.4 1.3
Alzheimer’s Disease (including proxy) 0.2 0.3 1.6 -0.0 0.1 -0.1 0.0 -0.3 -0.7 -0.1 -0.9 0.3 -0.6 -0.1 -1.1 -0.6 -0.6 -1.1 -0.1 -0.2 -0.0 -1.3 0.0 -0.7 0.2 0.4 0.5 0.2 -0.0 0.4 0.2
Crohns Disease (2017) 0.3 0.6 2.0 -0.3 0.9 -0.2 0.0 0.4 -1.1 -0.5 0.3 1.1 -1.0 -0.7 0.3 0.7 -1.3 -0.2 0.1 -0.5 0.5 0.0 -0.5 -1.0 0.5 1.4 1.3 0.6 0.0 0.9 1.1
Irritable Bowel Disease (IBD) 1.4 3.4 9.7 -1.2 0.0 -1.7 -1.1 -0.5 -2.8 -1.6 -1.5 1.9 -2.7 -2.4 -1.3 0.1 -3.1 -1.8 -2.3 -1.9 0.2 -1.3 -2.3 -2.9 0.6 3.0 2.1 0.2 -0.2 1.9 2.2
Ulcerative Colitis (UC) 2.5 4.6 10.8 -1.0 -0.4 -2.0 -1.3 -1.1 -3.1 -1.7 -2.3 1.8 -3.2 -2.9 -2.1 -0.2 -3.3 -2.5 -3.2 -2.3 -0.2 -2.0 -2.6 -3.2 0.5 3.1 2.0 -0.1 -0.4 2.1 2.2
Major Depression (MDD) 0.2 0.3 2.9 -0.1 0.2 0.6 0.7 -0.4 -0.1 0.7 -0.4 -0.2 0.4 0.6 -0.7 -0.1 0.0 -0.7 1.7 0.5 -0.3 0.2 0.5 0.2 0.5 -0.4 0.0 0.7 0.0 0.0 -0.0
Reaction Time 0.7 1.3 3.0 -0.8 -0.8 -1.6 -1.4 -0.2 -1.2 -1.0 -0.3 1.4 -1.4 -1.6 -0.8 -0.2 -1.7 -0.6 -1.5 -1.4 0.8 -0.3 -0.8 -1.7 1.2 1.2 1.3 0.7 0.7 1.5 1.5
Verbal and Numeric Reasoning (VNR) 0.8 1.9 8.3 -2.9 -2.4 -1.4 -1.4 -1.5 -0.2 -1.4 -0.8 -1.4 0.9 -0.3 -0.5 -2.4 0.6 -0.2 -1.6 -0.4 -0.3 -0.5 -1.8 0.4 -1.9 -1.3 -1.8 -1.4 -0.4 -1.3 -1.3
Breast Cancer 4.2 10.1 20.5 -0.8 0.7 -3.6 -2.8 0.3 -2.6 -1.9 -2.7 4.2 -4.2 -4.5 -3.6 -1.6 -4.4 -2.5 -2.9 -3.7 1.9 -3.0 -2.0 -4.2 3.1 4.2 3.8 2.5 1.8 4.3 4.4
Ovarian Cancer 0.2 0.3 2.1 -1.0 -0.5 -0.0 -0.2 -0.2 -0.2 -0.4 -0.5 -0.0 -0.2 -0.0 -0.3 -1.4 -0.2 -1.1 -0.9 0.0 -0.5 0.0 -0.8 0.1 -0.5 0.2 -0.1 -0.2 -0.6 -0.2 -0.1
Prostate Cancer 2.5 3.5 7.7 -0.3 -0.0 1.2 1.2 -0.6 0.8 0.4 2.5 -2.7 2.1 1.8 1.6 -0.8 2.1 2.0 -0.2 1.9 -2.4 1.4 -0.4 1.8 -2.5 -2.3 -2.6 -2.7 -2.6 -2.7 -2.8
Age at First Birth 1.5 2.2 11.4 0.2 -0.7 -1.7 -1.4 1.0 0.1 -0.4 -2.6 1.7 -1.2 -1.9 -2.3 0.6 -0.9 -1.2 -1.1 -1.7 1.6 -3.4 0.1 -1.0 1.2 1.4 1.3 1.3 1.7 1.5 1.7
Bipolar Disorder (2011) 1.9 1.8 4.3 0.2 -0.0 -1.6 -1.6 0.0 -0.8 -0.8 -0.9 1.8 -1.6 -2.0 -1.6 -0.3 -1.8 -0.1 -0.4 -1.8 1.0 -0.5 -0.3 -1.7 1.8 1.5 1.7 1.5 1.2 2.1 1.9
Body Mass Index (BMI) (2010) 0.8 1.1 2.4 1.4 1.3 0.2 -0.2 0.8 0.5 0.5 0.6 1.4 -1.1 -0.2 0.0 1.5 -0.6 1.0 0.7 -0.6 1.1 0.8 1.2 -0.9 1.6 1.3 1.5 1.2 1.1 1.5 1.4
Coronary Artery Disease (CAD) 0.6 0.7 4.4 0.4 -0.2 0.8 0.3 2.1 1.5 0.3 0.2 0.9 0.3 0.7 -0.3 1.1 0.8 0.6 0.0 0.4 1.2 0.9 1.2 0.7 0.8 0.2 0.3 0.8 1.2 0.4 0.7
Crohns Disease (2012) 0.6 1.0 5.2 -0.5 1.6 0.4 1.1 -0.5 -1.7 0.2 0.4 0.1 -0.4 -0.0 2.3 1.5 -1.3 0.1 -0.1 0.5 -1.3 1.1 -0.8 -1.1 -0.5 0.9 0.6 -0.3 -1.8 -0.1 -0.0
Mean Putamen Volume 0.9 1.1 3.8 0.3 0.6 1.2 1.3 1.1 1.8 1.9 0.9 0.0 0.9 1.3 0.2 0.4 1.4 0.8 1.2 1.2 0.5 0.3 1.9 1.5 0.9 -0.6 0.1 1.1 0.7 -0.2 -0.2
Fasting Glucose 0.8 1.0 3.0 0.9 0.5 1.5 1.0 0.6 1.7 1.2 0.5 -0.7 0.8 1.5 -0.1 0.6 1.6 0.3 1.3 1.0 0.5 -0.2 1.7 1.6 -0.2 -0.9 -0.5 0.1 0.5 -0.4 -0.9
HbA1C 4.2 4.7 15.5 1.0 2.8 3.9 3.9 1.6 1.8 3.5 1.9 -0.7 2.1 3.1 2.0 2.3 1.8 1.6 2.8 3.2 -0.9 2.0 2.8 2.3 0.7 -0.6 0.1 1.1 -1.1 -1.1 -0.7
HDL Cholesterol 1.9 3.1 8.5 2.9 0.5 -0.3 -0.5 1.9 -0.3 -0.3 -2.8 2.5 -2.0 -1.1 -1.8 2.2 -1.5 -1.7 0.5 -1.2 2.0 -1.7 0.9 -1.3 1.8 2.3 2.3 1.9 1.7 2.1 2.4
LDL Cholesterol 0.9 1.5 5.8 -1.2 0.5 1.0 0.9 -0.1 1.3 1.1 2.4 -1.2 1.5 1.6 1.7 0.6 1.6 1.6 0.4 1.4 -0.4 0.7 0.8 1.4 -0.8 -1.5 -1.3 -0.6 -0.5 -1.2 -1.4
Lupus 0.8 1.2 6.2 -0.1 -0.9 -1.1 -1.0 -0.9 -1.1 -1.2 -2.5 0.4 -1.4 -1.4 -1.1 -0.5 -1.1 -2.0 -1.4 -1.3 -0.5 -1.2 -1.2 -1.5 -0.4 0.9 0.4 -0.5 -0.4 0.5 0.5
Neuroticism (2016) 0.9 1.3 5.5 0.1 0.8 0.0 0.2 1.0 -0.2 0.8 -1.9 1.6 -0.9 -0.8 -2.4 0.2 -0.9 -0.2 0.4 -0.3 0.7 -1.5 0.5 -0.7 2.3 0.6 1.5 2.2 0.4 1.3 1.6
Primary Biliary Cirrhosis 0.3 0.4 0.8 -0.5 0.3 0.7 0.5 0.0 0.4 0.2 -0.0 -0.8 0.8 0.8 0.9 -0.5 0.8 -0.1 0.7 0.7 -0.7 0.5 0.2 0.9 -0.6 -0.9 -0.6 -0.1 -0.6 -0.9 -0.8
Rheumatoid Arthritis 1.8 2.5 6.9 0.3 -0.0 2.5 1.9 2.2 2.6 2.1 0.8 -0.8 2.0 2.5 0.3 0.7 2.5 1.4 0.8 2.0 0.2 1.5 1.9 2.6 -0.3 -1.4 -0.9 -0.0 0.0 -1.4 -1.1
Schizophrenia (2014) 0.2 0.4 3.2 -1.1 1.8 0.1 0.4 -0.2 -0.5 0.2 1.1 0.1 0.1 0.2 0.9 -0.5 -0.4 1.6 -0.2 0.5 -0.2 -0.1 0.1 -0.1 0.5 -0.1 0.4 0.9 -0.5 0.1 0.1
Triglycerides 0.3 0.5 1.4 -1.0 -0.2 0.2 0.3 -0.6 0.1 0.1 1.2 -0.9 0.7 0.6 0.9 -1.0 0.7 -0.0 -0.3 0.5 -0.6 1.1 -0.4 0.7 -0.8 -1.0 -0.9 -0.5 -0.6 -0.9 -1.0
Type 2 Diabetes (T2D) (2012) 0.4 0.5 2.8 -0.2 -1.1 -0.4 -0.7 -0.2 -0.0 -0.8 -1.4 -0.3 -0.3 -0.3 -1.2 -0.9 0.4 -1.2 0.2 -0.8 -0.2 -1.7 -0.2 0.0 -0.7 -0.2 -0.4 -0.4 0.6 -0.3 -0.4
Ulcerative Colitis 1.3 1.9 5.6 -0.6 0.0 -1.6 -1.2 -1.3 -1.9 -1.3 -1.2 1.1 -2.0 -2.2 -0.3 0.6 -2.4 -0.4 -1.8 -1.8 -0.3 -0.8 -1.6 -2.4 0.3 1.9 1.2 -0.0 -0.3 1.4 1.2
Blood Eosinophil Count 1.6 12.5 34.3 -0.4 3.5 3.9 5.0 -2.3 -0.6 3.2 5.9 -4.1 2.9 4.3 5.1 2.2 1.8 4.3 1.8 4.9 -5.3 2.1 0.4 1.7 -2.5 -2.6 -2.6 -3.2 -5.5 -3.7 -3.7
Blood Platelet Count 0.3 3.9 16.2 4.0 -0.0 3.0 1.6 2.3 2.5 1.8 0.8 -1.3 1.7 3.4 -0.4 2.4 2.6 1.2 2.4 1.8 0.4 0.9 3.2 2.2 -0.5 -2.1 -1.4 -0.4 0.4 -1.2 -1.3
Blood Red Count 1.2 11.7 53.0 -3.4 5.3 1.0 4.2 -4.8 -5.0 1.4 6.6 -2.1 -0.4 -0.2 4.2 -2.8 -2.7 2.4 -1.6 3.0 -6.9 -0.5 -3.2 -1.1 -0.8 0.5 0.3 -1.8 -7.3 -1.5 -1.4
Blood White Count 1.0 7.7 36.7 -2.3 -0.6 0.8 1.6 -2.0 -0.6 0.5 6.1 -3.6 2.7 2.0 4.2 0.1 1.6 3.2 -0.2 2.4 -3.7 3.3 -1.6 1.5 -3.0 -3.0 -3.2 -3.4 -3.7 -3.4 -3.5
Heel T-Score 1.1 9.0 20.9 -0.9 2.5 4.0 4.3 0.5 2.1 3.8 4.1 -3.1 4.3 3.9 3.2 -1.2 3.4 2.0 1.4 4.6 -2.5 2.3 1.2 4.1 -0.8 -3.8 -2.4 -0.3 -2.9 -3.5 -2.9
BMI 1.2 6.8 16.6 1.7 2.2 4.1 3.0 2.2 3.8 3.9 3.3 -1.3 2.9 3.9 1.4 0.9 3.7 3.4 2.7 3.1 -0.2 2.1 3.5 3.4 0.6 -2.6 -1.4 0.6 -0.1 -1.5 -1.2
Height 0.1 1.3 3.2 -0.9 1.6 -0.4 0.9 0.3 -1.1 1.0 -0.3 1.5 -1.2 -1.5 -1.2 -0.6 -1.5 -0.7 0.5 0.0 -0.3 -1.2 -0.1 -1.3 1.6 1.7 1.8 1.4 -0.4 1.3 1.5
Waist Hip Ratio (WHR) 0.1 0.7 4.4 -0.6 0.3 -0.1 -0.3 0.2 1.2 -0.1 2.1 -0.5 0.9 0.3 1.1 0.3 1.0 1.4 1.1 0.0 0.6 1.6 0.9 0.8 -0.1 -0.7 -0.5 0.1 0.6 -0.3 -0.5
Systolic Blood Pressure 0.3 1.7 6.4 0.8 -1.8 0.4 -0.1 1.2 2.4 0.1 -0.7 -1.4 1.9 0.9 -0.7 -0.8 2.5 0.7 0.3 0.4 0.5 0.3 1.0 2.1 -1.3 -2.1 -2.1 -1.0 0.7 -1.5 -1.5
Smoking Status 1.3 3.2 13.1 1.8 0.4 1.5 0.6 2.4 3.6 1.8 1.7 0.1 1.5 1.6 -0.4 1.4 2.5 1.9 2.7 0.6 2.2 1.6 3.4 2.0 1.0 -1.3 -0.5 1.3 2.4 -0.0 -0.1
Allergy or Eczema 0.4 1.0 4.5 -0.8 -1.6 -0.9 -1.2 -1.0 -1.2 -1.8 -2.1 -0.5 -0.2 -0.7 0.2 0.7 -0.8 -0.1 -0.0 -0.9 -0.6 0.3 -1.4 -1.0 -1.7 0.2 -0.8 -1.7 -0.6 -0.5 -0.5
Cardiovascular Disease 0.5 1.7 3.9 1.1 1.0 1.7 1.8 1.2 1.7 1.7 0.5 -1.1 1.6 1.4 -0.4 -1.4 2.0 0.3 1.2 1.7 -0.9 -1.0 1.8 1.9 -0.1 -1.7 -1.2 -0.2 -0.8 -1.1 -1.3
Hypothyroidism (self reported) 2.9 6.8 15.0 1.3 1.4 3.6 3.0 1.5 2.6 2.5 3.0 -2.5 3.5 3.9 2.7 1.0 3.5 2.7 2.2 3.5 -1.0 3.0 2.0 3.6 -1.2 -3.5 -2.4 -0.6 -1.0 -2.9 -2.5
Respiratory disease 1.5 3.3 8.3 2.9 1.9 0.5 0.2 2.6 0.5 0.9 -0.6 2.8 -1.3 -0.6 -0.3 1.7 -1.1 -0.3 1.0 -0.8 2.4 0.6 1.7 -0.7 2.9 2.1 2.7 2.8 2.4 2.4 2.7
Type 2 Diabetes (T2D) (2018) 2.8 5.2 12.0 0.0 0.5 2.5 2.3 0.9 2.6 2.4 2.5 -2.4 3.0 3.3 2.9 0.6 3.5 2.3 2.1 2.9 -0.8 2.4 2.4 3.3 -1.0 -3.2 -2.2 -0.6 -0.4 -2.5 -2.3
Lung FEV1/FVC ratio 1.0 5.1 20.1 3.4 -2.1 -1.3 -2.5 1.5 0.3 -1.7 -4.5 2.2 -2.5 -1.8 -4.5 0.5 -1.1 -3.2 -1.4 -2.7 2.9 -2.3 0.5 -1.4 0.8 1.7 1.2 1.0 2.8 2.2 2.1
Lung FVC 0.3 1.3 4.7 0.2 -0.6 -0.3 -0.2 -1.6 -1.1 -1.4 0.8 -1.3 -0.1 0.1 1.1 -0.9 0.0 -0.4 -1.4 0.0 -1.1 1.6 -1.7 0.0 -2.2 -0.6 -1.3 -2.1 -1.1 -1.3 -1.4
Neuroticism 0.3 0.7 3.2 -0.6 -0.0 -0.9 -0.0 -0.8 -1.8 -0.6 -1.2 0.0 -0.7 -1.1 -0.8 -0.3 -1.2 -0.9 -1.1 -0.3 -1.1 -0.6 -1.8 -1.2 -0.1 -0.1 -0.1 -0.4 -1.3 -0.0 0.3
Chronotype (morning person) 0.5 1.2 3.8 0.9 1.3 1.3 1.1 1.8 0.9 1.6 -0.4 1.2 -0.2 0.4 -1.2 1.9 0.2 1.4 1.0 0.5 1.0 0.2 1.7 -0.1 1.7 0.5 1.1 1.4 0.9 0.8 1.0
Hair Pigment 0.0 1.3 5.3 0.2 -2.3 -1.7 -2.1 -0.6 -0.8 -1.9 -0.5 0.5 -0.6 -1.6 -1.0 -1.4 -1.0 -1.2 -0.3 -1.9 0.8 0.8 -1.6 -0.9 -0.5 0.0 -0.4 -0.6 0.8 0.5 0.3
Tanning 0.2 2.1 6.6 1.1 2.5 0.9 0.7 2.0 0.3 1.1 -0.4 2.2 -1.2 -0.4 -1.1 0.9 -0.9 -0.7 -0.7 -0.3 1.3 -0.9 0.9 -0.7 2.3 1.8 2.3 2.6 1.1 1.8 2.1
Hand grip strength (left) 0.2 0.6 2.2 0.3 1.0 0.7 1.3 -0.3 -1.2 0.9 -0.8 0.3 -0.5 -0.2 -1.1 -0.8 -1.0 -0.7 -0.4 0.4 -1.1 -1.5 -0.8 -0.6 0.7 0.7 0.7 0.2 -1.2 0.3 0.5
Number of treatments/medications taken 0.7 1.3 4.9 1.9 1.7 1.7 1.1 1.4 1.4 1.5 -0.2 0.3 0.5 1.3 -0.6 -0.6 1.0 -0.3 1.4 1.0 0.5 -0.2 2.2 1.2 1.3 -0.4 0.5 1.7 0.7 0.2 0.2
Average weekly spirits intake 2.8 3.4 8.0 0.3 1.3 2.8 2.5 -0.5 0.6 1.8 2.3 -2.2 2.0 2.8 2.8 0.5 1.8 1.4 1.0 2.7 -2.1 1.1 1.0 2.0 -1.3 -2.0 -1.6 -0.9 -1.9 -2.2 -2.1
Sensitivity / hurt feelings 0.3 0.5 1.8 -0.6 0.1 0.5 0.9 0.3 0.2 0.7 -0.7 -0.6 1.1 0.6 -0.5 -0.2 0.8 -0.3 -0.7 1.0 -0.7 0.2 -0.7 0.8 -0.4 -1.4 -0.9 -0.1 -1.0 -1.1 -0.6
Frequency of depressed mood in last 2 weeks 0.5 0.7 3.4 1.5 1.7 0.6 0.4 1.4 0.7 0.4 1.5 0.3 0.3 0.1 0.1 1.0 0.5 1.8 0.5 0.2 0.7 -0.1 0.7 0.5 0.7 -0.5 0.1 1.0 0.7 0.1 0.3
Hearing difficulty/problems: Yes 1.1 1.7 5.9 -1.0 2.0 -0.4 0.3 0.2 -2.1 0.1 0.4 1.6 -1.4 -1.3 0.6 0.0 -2.4 -0.6 -1.1 -0.2 -0.7 -0.9 -1.3 -1.8 1.6 2.1 2.0 1.1 -1.0 1.5 1.5
Relative age of first facial hair 0.3 0.6 3.1 -0.6 -1.0 -0.7 -0.3 -1.7 -1.4 -1.0 -0.6 -0.6 -0.4 -0.5 -0.1 -0.7 -0.8 -0.3 0.6 -0.3 -0.9 -0.5 -1.0 -0.7 -0.8 0.3 -0.2 -1.1 -1.0 -0.3 -0.4
Other serious medical condition/disability diagnosed by doctor 0.6 0.8 2.6 1.1 1.5 1.6 1.6 0.8 0.2 1.3 1.3 -0.3 0.6 1.4 0.4 0.0 0.5 -0.0 -0.9 1.4 -0.6 -0.4 0.4 0.7 0.3 -0.6 -0.1 0.6 -0.7 -0.6 -0.3
Ever used hormone-replacement therapy (HRT) 0.3 0.4 2.2 -0.3 -0.1 -0.0 -0.0 0.5 -0.6 0.2 -1.2 0.9 -0.4 -0.2 -1.1 -0.2 -0.8 -1.5 -1.1 -0.2 -0.0 -0.0 -0.3 -0.7 0.8 0.8 0.8 0.7 0.0 0.7 0.7
Ever had hysterectomy (womb removed) 2.0 2.2 7.2 0.9 1.5 2.7 2.3 1.4 1.6 2.6 1.4 -0.2 1.1 2.4 0.8 1.3 1.5 1.3 1.3 2.1 0.3 0.6 2.7 1.5 1.1 -0.6 0.3 1.4 0.3 -0.4 -0.2
Systolic blood pressure, automated reading 1.1 3.1 11.0 0.1 -0.7 1.7 1.0 1.3 2.9 1.4 0.6 -1.9 3.0 2.1 0.3 -0.6 3.3 1.9 0.3 1.6 0.0 0.7 1.3 3.1 -1.1 -2.8 -2.3 -0.7 0.2 -2.2 -1.8
Eye problems/disorders: Diabetes related eye disease 0.7 0.8 5.5 0.3 0.4 0.5 0.5 0.2 0.7 0.4 1.5 -0.4 0.8 0.3 0.8 0.4 0.6 2.3 1.4 0.5 -0.4 2.2 0.8 0.7 -0.1 -0.7 -0.5 -0.2 -0.3 -0.5 -0.6
Angina 0.5 0.7 3.6 1.9 1.1 1.3 1.2 0.3 0.3 0.9 1.1 -0.2 0.4 1.1 0.7 1.2 0.2 0.9 0.7 1.1 -0.3 0.5 1.2 0.6 0.2 -0.0 0.2 0.4 -0.5 -0.2 -0.2
Medication for hormone replacement therapy 0.6 0.7 3.5 -0.4 0.4 0.8 1.0 -0.6 -0.5 0.6 1.1 -0.9 0.8 0.7 0.7 -1.2 0.2 -0.2 -0.0 1.0 -1.9 1.1 -0.4 0.4 -0.4 -0.8 -0.7 -0.8 -1.8 -0.8 -0.6
Vitamin and mineral supplements 0.7 1.0 5.6 -2.1 -1.7 -1.7 -1.4 -0.5 -0.5 -1.1 0.2 0.3 -0.8 -1.2 -0.1 -0.1 -0.6 0.0 -2.4 -1.1 -0.1 0.1 -1.6 -1.0 -0.7 0.7 -0.1 -1.1 -0.1 0.3 0.5
Supplements: Zinc 0.9 1.0 4.7 0.9 0.6 1.3 1.0 0.1 1.2 0.9 0.1 -0.8 1.0 1.5 1.1 0.8 1.1 0.8 1.9 1.1 -0.1 2.2 1.4 1.2 -0.4 -0.5 -0.3 0.2 -0.0 -0.8 -1.0
Medication: Co-codamol 0.9 1.1 4.2 1.7 1.3 2.0 1.8 0.1 0.2 1.4 1.5 -0.5 0.5 1.5 0.7 1.0 0.5 0.9 0.6 1.5 -0.8 0.8 1.1 0.9 0.5 -0.6 0.0 0.5 -0.8 -0.4 -0.7
Medication: Metformin 2.1 2.9 6.9 -0.0 0.7 2.4 2.3 -0.2 1.0 1.8 1.6 -2.0 2.1 2.6 1.8 -0.2 2.0 1.0 1.3 2.5 -1.6 2.2 1.3 2.0 -0.9 -2.3 -1.6 -0.6 -1.3 -2.0 -2.1
Diabetes (father) 0.9 1.2 3.2 -0.8 -1.4 0.5 0.2 -0.2 0.6 -0.2 0.8 -1.5 1.2 0.9 0.5 -0.5 1.4 0.7 -1.3 0.6 -0.8 0.7 -0.6 1.0 -1.6 -1.6 -1.8 -1.7 -0.8 -1.6 -1.4
Diabetes (mother) 0.5 0.6 2.2 0.6 -0.7 -1.3 -1.4 0.4 0.2 -0.8 0.4 0.7 -0.7 -0.9 -0.6 0.0 -0.3 0.1 0.3 -1.4 1.3 1.0 0.1 -0.5 0.5 0.0 0.1 0.3 1.5 0.9 0.6
Severe depression (siblings) 0.4 0.4 2.3 -0.0 1.5 1.0 1.1 -0.2 -0.1 0.8 -1.1 -0.0 0.2 0.6 -0.7 0.1 -0.0 0.1 1.0 0.9 -0.5 -0.3 0.8 0.2 0.9 -0.2 0.5 1.2 -0.4 0.0 0.1
Pack years adult smoking proportion 0.3 0.5 3.0 1.1 0.9 0.8 0.6 0.6 0.4 0.6 0.9 -0.2 0.6 0.7 0.5 1.2 0.3 1.7 1.1 0.7 -0.3 0.1 0.7 0.5 0.4 -0.5 0.0 0.3 -0.4 -0.2 -0.1
Impedance of leg (right) 0.2 0.9 2.0 0.1 -1.1 -1.2 -1.1 -1.1 -1.1 -1.4 -0.7 0.6 -1.4 -1.2 -0.8 0.1 -1.4 -1.4 -0.7 -1.3 0.1 -0.2 -0.6 -1.4 0.0 1.4 0.8 -0.1 0.2 1.0 0.8
Leg fat-free mass (left) 0.2 1.0 3.1 0.1 1.5 1.3 1.2 1.4 1.4 1.8 0.3 0.1 1.0 0.9 -0.3 0.2 1.2 1.4 1.6 1.1 0.4 -0.1 1.3 1.2 0.7 -0.8 -0.2 0.9 0.1 -0.3 0.1
Trunk fat percentage 0.5 1.9 4.8 0.8 0.8 1.9 1.0 1.1 2.2 1.6 2.2 -0.8 1.5 1.8 0.5 -0.5 2.1 2.0 1.8 1.3 -0.1 1.4 1.8 1.8 0.0 -1.7 -1.0 0.2 -0.1 -0.9 -0.6
Hand grip strength (right) 0.7 1.9 6.2 -0.4 -0.1 -0.8 -0.4 -1.1 -2.5 -0.9 -2.3 0.7 -1.5 -1.4 -2.2 -1.7 -2.2 -1.4 -1.2 -0.9 -0.8 -2.0 -2.2 -1.8 0.4 1.4 0.9 -0.1 -1.0 0.8 0.8
Townsend deprivation index at recruitment 0.9 1.3 3.6 -0.4 -1.3 0.6 0.2 0.1 1.1 0.2 1.4 -1.4 1.8 1.2 1.7 0.6 1.6 1.7 0.2 0.8 -0.3 0.8 0.2 1.5 -1.0 -1.9 -1.6 -0.8 -0.3 -1.5 -1.2
Current tobacco smoking 1.0 1.6 7.1 1.1 1.0 1.3 0.9 0.8 1.6 1.1 1.5 -0.4 0.9 1.5 0.9 1.6 1.3 1.6 2.7 0.9 0.8 2.2 2.4 1.1 0.4 -0.9 -0.4 0.3 0.9 -0.3 -0.3
Average weekly fortified wine intake 1.3 1.5 8.4 1.6 2.9 1.9 2.3 0.9 -0.6 1.9 0.5 0.8 -0.7 0.5 -0.1 0.7 -0.8 -0.7 0.4 1.1 -0.9 -0.5 0.9 -0.3 1.7 1.0 1.6 1.5 -1.0 0.7 0.9
Maternal smoking around birth 1.2 1.7 5.0 1.4 -1.4 -0.5 -1.0 -1.5 0.2 -1.1 1.1 -1.9 1.3 0.3 0.7 -1.3 1.0 1.5 1.1 -0.3 -0.8 1.0 -0.5 0.5 -1.7 -2.1 -2.2 -2.1 -0.6 -1.4 -2.1
Fed-up feelings 0.9 1.6 3.7 0.6 -0.5 -1.9 -1.8 -0.4 -1.4 -1.7 -0.6 1.4 -1.6 -1.8 -1.3 -0.1 -1.8 -0.5 -0.8 -1.8 0.8 -0.5 -1.1 -1.7 1.0 0.8 0.9 0.7 0.8 1.5 1.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.3 6.9 2.3 2.6 0.9 0.8 1.0 0.1 0.9 1.5 1.1 -0.5 -0.1 -0.2 0.8 -0.4 1.8 0.3 0.1 0.7 0.1 1.1 -0.2 1.7 0.6 1.2 1.6 0.7 1.0 1.1
Relative age voice broke 0.4 0.6 2.4 0.4 -1.0 -0.8 -0.5 -1.3 -1.5 -1.1 0.5 -0.1 -0.8 -0.8 0.2 -0.9 -1.1 -0.3 1.1 -0.6 -0.9 -0.1 -1.0 -0.9 -0.5 0.3 -0.0 -1.1 -1.0 0.0 -0.1
Taking other prescription medications 0.6 0.9 4.2 2.0 0.6 1.0 0.6 1.5 0.6 1.0 -0.6 0.9 -0.3 0.8 -1.1 0.4 0.3 -0.8 0.6 0.4 0.9 -0.8 1.4 0.5 1.4 0.3 0.8 1.6 1.0 0.6 0.5
Age when periods started (menarche) 0.5 1.1 3.3 -0.3 -0.7 -1.7 -1.7 -1.1 -1.0 -1.5 -0.1 0.8 -1.2 -1.8 -0.5 -0.6 -1.5 0.3 -0.8 -1.8 0.3 0.0 -1.3 -1.7 0.3 1.0 0.7 -0.1 0.1 1.1 1.1
Bilateral oophorectomy (both ovaries removed) 3.3 3.8 8.7 0.5 1.4 2.9 2.9 1.3 1.8 2.5 2.8 -1.5 2.6 2.8 1.9 0.2 2.5 2.3 0.6 2.9 -0.9 1.6 1.8 3.0 -0.4 -1.9 -1.2 0.2 -0.9 -2.0 -1.7
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.3 5.6 -0.2 0.5 1.7 1.8 -0.9 0.5 1.0 0.8 -2.3 1.6 1.7 1.0 -0.9 1.4 0.5 0.8 2.1 -2.4 1.1 0.1 1.6 -1.6 -1.7 -1.7 -1.6 -2.3 -2.1 -2.2
Tinnitus: Yes, but not now, but have in the past 1.9 2.0 11.2 3.3 0.5 -0.4 -0.6 0.3 -1.7 -0.9 0.0 1.7 -2.4 -1.4 -1.8 -0.6 -2.1 -0.5 -0.8 -1.5 0.4 -1.1 -0.5 -1.8 1.4 1.8 1.7 0.7 0.4 1.9 1.6
Qualifications: CSEs or equivalent 0.4 0.5 2.0 0.7 -0.7 0.2 -0.0 -0.4 0.4 -0.3 0.2 -1.1 0.8 0.4 0.6 -0.2 0.7 0.1 1.4 0.2 -0.9 0.5 0.1 0.5 -1.0 -1.1 -1.1 -1.0 -0.7 -0.9 -0.8
Serious illness, injury or assault to yourself 0.7 0.8 3.7 0.1 1.3 1.5 1.9 1.3 0.1 1.8 0.7 0.2 0.5 1.3 0.2 1.6 0.1 0.7 0.1 1.5 -0.2 -0.3 1.0 0.3 0.5 0.5 0.6 0.6 -0.5 -0.2 0.1
High blood pressure 0.4 1.0 5.9 2.4 1.3 0.7 0.6 1.8 1.6 0.9 -0.2 0.3 0.2 0.3 -0.6 -0.3 1.2 0.6 0.9 0.3 0.7 -1.2 1.9 1.1 0.8 -0.4 0.1 0.7 0.9 0.2 0.1
Hayfever, allergic rhinitis or eczema 0.6 1.3 7.6 -0.5 -1.4 -1.2 -1.4 -0.8 -1.6 -2.0 -2.8 0.3 -1.0 -1.2 -0.8 0.3 -1.4 -1.0 -0.3 -1.3 -0.2 -0.1 -1.4 -1.6 -0.9 0.7 -0.1 -0.9 -0.3 0.3 0.2
Multivitamins +/- minerals 1.7 2.1 5.3 1.4 1.4 2.3 1.7 1.3 1.9 1.5 0.2 -1.0 1.9 2.0 0.7 -0.0 2.1 0.6 2.2 1.8 0.0 1.3 1.8 2.3 -0.1 -1.9 -1.0 0.6 0.0 -1.3 -1.3
Stomach or abdominal pain in last month 0.7 0.9 2.7 0.7 1.7 0.4 0.6 -0.2 -1.3 0.5 0.9 0.7 -0.8 -0.0 1.0 1.3 -1.4 0.3 -1.4 0.1 -0.7 0.7 -0.4 -1.3 1.2 1.0 1.2 0.8 -0.7 0.9 0.9
Supplements: Glucosamine 2.3 3.0 10.3 1.8 1.8 3.0 2.2 1.7 2.6 2.9 0.8 -0.2 1.2 2.4 0.8 1.6 2.2 0.7 1.8 1.9 0.7 0.8 3.2 2.1 1.1 -1.0 0.0 1.5 0.9 -0.3 -0.4
Diverticular disease/diverticulitis (self-reported) 0.2 0.3 1.8 -0.1 1.3 0.3 0.5 -0.1 -0.2 0.6 1.0 -0.1 0.1 0.1 0.4 -0.8 -0.1 0.1 -0.9 0.4 -0.7 -0.6 -0.4 -0.1 0.5 -0.4 0.1 0.2 -0.7 -0.0 0.1
Medication: Atenolol 0.9 1.1 4.4 0.9 0.4 1.2 1.0 1.6 1.8 1.5 0.7 0.3 0.9 1.2 -0.1 0.9 1.4 1.0 0.9 1.1 1.0 0.3 2.1 1.6 1.0 -0.5 0.1 1.2 1.1 -0.0 0.2
Medication: Levothyroxine sodium 1.2 2.0 4.8 1.1 1.3 2.2 1.8 1.0 0.7 1.1 1.8 -1.2 1.7 2.1 1.9 0.1 1.5 1.2 1.2 1.9 -0.9 1.5 0.7 1.7 -0.5 -1.9 -1.2 -0.2 -0.8 -1.7 -1.2
Sitting height 0.3 2.0 5.8 -1.5 0.8 -1.5 -0.1 -0.2 -1.8 -0.2 -0.7 1.8 -1.9 -2.4 -1.2 0.4 -2.4 -0.1 -0.8 -0.9 -0.4 -0.8 -0.9 -2.2 1.2 2.4 1.8 0.5 -0.5 1.7 2.1
Chronic bronchitis/emphysema (father) 1.5 1.7 6.0 0.4 0.4 -1.1 -1.1 -0.8 -2.4 -1.5 -1.5 1.0 -1.8 -1.5 -0.5 -1.2 -2.4 -1.6 -1.2 -1.3 -0.4 -0.1 -1.8 -2.2 0.3 1.4 1.1 -0.0 -0.6 1.2 1.1
High blood pressure (mother) 0.2 0.2 2.6 1.6 0.2 -0.2 -0.2 0.6 0.2 -0.2 -0.4 0.1 0.1 -0.2 -0.7 -0.4 0.2 0.2 0.4 -0.3 0.6 0.1 0.3 0.4 0.5 -0.8 -0.1 0.6 0.6 0.1 -0.1
Body mass index (BMI) 0.8 3.3 8.4 1.5 1.2 2.7 1.6 1.9 2.9 2.3 2.2 -1.0 2.2 2.5 0.4 0.0 2.8 2.4 2.0 1.8 0.1 1.2 2.2 2.6 0.2 -2.2 -1.3 0.3 0.1 -1.3 -0.8
Impedance of leg (left) 0.2 0.8 2.1 -0.6 -1.4 -1.2 -1.1 -1.1 -0.9 -1.2 -0.4 0.4 -1.0 -1.1 -0.4 -0.0 -1.2 -1.2 -0.9 -1.1 -0.2 0.5 -0.8 -1.3 -0.1 1.2 0.6 -0.2 0.1 0.7 0.5
Leg predicted mass (left) 0.2 1.0 3.3 0.1 1.6 1.4 1.3 1.4 1.4 1.8 0.4 0.1 1.0 0.9 -0.2 0.2 1.2 1.4 1.6 1.2 0.3 -0.1 1.4 1.2 0.7 -0.8 -0.1 0.9 0.1 -0.3 0.1
Trunk fat mass 0.5 2.3 6.0 0.9 1.2 2.1 1.3 1.5 2.5 2.1 2.0 -0.6 1.6 1.9 0.3 -0.1 2.2 2.3 2.2 1.5 0.0 1.4 2.1 1.9 0.4 -1.6 -0.8 0.5 0.0 -0.8 -0.5
Waist circumference 0.9 3.4 11.6 0.9 1.4 2.3 1.3 2.2 3.4 2.4 2.1 -0.6 2.2 2.1 0.5 0.6 2.9 2.6 2.4 1.6 0.8 1.7 2.8 2.6 0.7 -2.0 -0.9 0.9 0.8 -0.8 -0.6
Number of incorrect matches in round 0.8 1.3 6.8 1.8 2.6 1.6 2.0 0.4 -0.4 1.6 1.3 0.2 0.3 0.7 1.6 1.7 -0.4 1.3 -0.6 1.3 -1.3 -0.4 0.2 0.2 0.9 0.5 0.8 0.5 -1.4 -0.0 0.3
Past tobacco smoking 1.1 2.0 9.3 -1.5 -0.2 -1.4 -0.6 -1.9 -3.0 -1.6 -1.3 0.1 -1.6 -1.4 -0.2 -0.3 -2.2 -1.3 -1.8 -0.7 -1.3 -1.3 -2.4 -1.9 -0.6 1.4 0.6 -1.0 -1.5 0.3 0.4
Alcohol usually taken with meals 0.4 0.7 1.6 -1.0 0.2 0.9 0.9 -0.3 -0.1 0.8 1.2 -0.8 1.0 1.0 0.9 -1.3 0.5 1.0 -0.1 1.2 -0.9 0.9 -0.1 0.9 -0.1 -1.1 -0.7 -0.1 -0.7 -0.9 -0.9
Nervous feelings 0.6 1.1 3.1 1.5 -0.3 -1.2 -1.1 1.3 -0.2 -1.1 -1.8 1.1 -0.8 -1.3 -1.4 0.4 -0.4 -1.1 -0.6 -1.1 1.7 -1.3 -0.3 -0.3 0.6 0.2 0.5 0.9 1.5 0.7 1.0
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.7 3.4 0.6 0.2 -0.7 -0.5 -0.6 -1.8 -1.1 -0.6 0.4 -1.0 -1.0 -0.6 -0.3 -1.5 -0.3 -1.4 -0.7 -0.2 -0.3 -1.3 -1.3 -0.0 0.5 0.2 -0.2 -0.5 0.5 0.5
Hearing difficulty/problems with background noise 1.1 1.7 7.9 0.0 1.1 -1.2 -0.5 -1.3 -2.8 -1.4 -0.1 0.6 -1.7 -1.8 0.3 -0.8 -2.5 -1.4 -1.5 -0.9 -1.2 -0.6 -2.0 -2.0 -0.1 1.3 0.8 -0.4 -1.5 0.8 0.5
Hair/balding pattern: Pattern 2 1.7 2.1 6.2 0.3 -0.8 -1.1 -0.9 -2.1 -2.3 -1.8 -0.9 -0.8 -1.0 -1.0 -0.2 -2.2 -1.4 -2.1 -2.0 -0.8 -1.8 -2.2 -2.5 -1.0 -1.5 0.2 -0.7 -1.8 -1.8 -0.3 -0.3
Had menopause 2.8 3.5 7.2 -0.6 0.9 -2.0 -1.7 -0.5 -2.0 -1.5 -1.1 2.2 -2.6 -2.5 -1.6 -1.5 -2.6 -2.2 -2.6 -2.0 0.6 -2.3 -1.2 -2.7 1.4 2.4 2.0 1.2 0.6 2.3 2.0
Had other major operations 0.9 1.1 4.3 -0.2 1.1 1.5 1.4 1.4 1.5 2.1 1.1 0.4 0.7 1.3 0.1 0.2 0.9 0.6 1.2 1.1 0.4 1.0 1.8 0.9 1.1 0.1 0.5 1.3 0.4 0.2 0.2
Forced vital capacity (FVC) 0.1 0.4 2.0 0.5 0.9 -0.0 0.4 -0.1 -0.6 0.0 0.1 0.6 -0.6 -0.5 0.0 1.4 -0.9 0.4 0.5 -0.1 0.0 1.1 -0.1 -0.8 0.3 1.2 0.8 0.2 -0.2 0.6 0.6
Heel bone mineral density (BMD) T-score, automated (right) 1.4 3.2 6.6 -0.3 0.1 1.9 1.8 -0.4 1.3 1.2 1.1 -2.6 2.4 2.3 1.2 -0.9 2.3 1.1 1.2 2.4 -2.1 1.7 0.3 2.4 -1.8 -2.3 -2.2 -1.6 -2.0 -2.5 -2.4
Ever unenthusiastic/disinterested for a whole week 1.8 2.2 6.6 1.7 1.7 0.0 0.1 2.0 0.6 0.7 -0.6 2.2 -1.1 -0.5 -0.6 2.1 -0.8 0.5 0.5 -0.5 2.0 -0.7 1.3 -0.4 2.6 1.3 2.1 2.6 2.0 1.9 2.0
Qualifications: None of the above 0.2 0.3 1.2 0.9 -0.9 -0.0 -0.3 -0.3 -0.2 -0.5 0.6 -0.6 0.4 0.0 0.5 1.0 0.2 1.1 -0.7 -0.2 -0.3 0.7 -0.7 -0.0 -0.6 -0.7 -0.7 -0.6 -0.4 -0.5 -0.4
Financial difficulties in last 2 years 1.0 1.3 4.0 -1.6 -1.7 0.1 -0.3 0.5 1.3 -0.2 -0.1 -1.4 1.8 0.8 -0.0 -0.3 1.8 0.8 0.2 0.5 -0.3 -0.0 -0.1 1.5 -1.6 -1.7 -2.0 -1.5 -0.2 -1.6 -1.5
Mouth/teeth dental problems 0.5 0.7 2.8 0.4 0.8 -0.2 0.2 -0.4 -0.8 0.2 -1.4 0.8 -1.3 -0.5 -0.6 0.5 -1.0 -1.0 0.2 -0.1 0.2 -1.4 0.4 -0.7 0.9 1.7 1.6 0.9 0.2 1.0 1.0
Heart attack 0.5 0.6 3.2 -0.6 0.4 0.3 0.6 -1.5 -0.8 0.4 1.0 -1.0 0.4 0.6 0.8 -0.6 -0.2 0.1 0.1 0.9 -1.7 0.4 -0.4 -0.3 -0.5 -0.4 -0.5 -0.8 -1.8 -0.6 -0.8
Allergy 0.2 0.4 3.4 -0.6 -0.3 -0.2 -0.0 -0.0 1.1 0.6 1.8 -0.4 0.6 0.4 0.4 -0.4 1.1 0.5 -0.0 0.3 0.6 -0.2 0.6 1.1 0.2 -0.7 -0.3 0.3 0.8 -0.2 -0.4
Pain all over the body in last month 1.3 1.4 5.2 2.2 2.3 0.8 0.9 1.3 -0.5 0.8 -0.0 1.5 -1.2 -0.2 -0.5 0.7 -1.3 -0.8 -0.6 0.1 0.4 -0.1 0.7 -0.9 1.7 1.4 1.8 1.8 0.3 1.4 1.5
Diabetes (self-reported) 3.9 6.1 12.5 -0.6 0.4 2.7 2.4 0.2 2.2 2.0 3.1 -2.9 3.3 3.5 3.3 0.3 3.5 2.7 1.1 3.1 -1.5 2.8 1.7 3.4 -1.6 -3.5 -2.6 -1.0 -1.0 -3.0 -2.9
Hayfever/allergic rhinitis (self-reported) 0.6 0.7 1.9 -0.8 -0.2 1.0 1.0 -0.1 0.4 0.6 -1.4 -1.0 1.2 1.4 0.2 0.6 1.0 -0.4 -0.8 1.3 -0.5 0.4 -0.0 1.1 -0.8 -1.1 -1.0 -0.5 -0.6 -1.2 -1.0
Medication: Ramipril 0.3 0.4 1.3 -0.8 -0.2 0.2 0.4 0.9 1.0 0.4 -1.0 -0.5 0.9 0.4 -0.0 -0.4 1.1 0.4 -0.8 0.7 -0.1 -0.8 0.3 1.0 -0.5 -0.9 -0.9 -0.2 -0.1 -0.8 -0.5
Medication: Simvastatin 1.6 2.3 5.9 0.4 0.6 1.9 1.8 1.4 2.4 2.3 1.7 -1.1 2.1 2.1 0.4 -0.3 2.4 1.3 1.6 1.9 -0.4 0.8 2.0 2.4 0.2 -1.9 -1.1 0.4 -0.2 -1.2 -1.2
Fluid intelligence score 0.5 1.0 6.6 -2.6 -1.6 -0.9 -1.0 -0.7 0.2 -0.8 -1.0 -1.0 0.9 -0.1 -0.3 -1.5 0.7 -0.1 -0.6 -0.2 -0.2 0.7 -1.0 0.3 -1.4 -1.2 -1.5 -0.8 -0.2 -1.0 -1.1
Illnesses of siblings 2.0 2.8 6.8 -0.7 -2.0 -2.4 -2.3 -2.0 -2.2 -2.1 -1.5 0.5 -2.1 -2.3 -1.5 -0.9 -2.2 -1.9 -0.8 -2.3 -0.4 -0.9 -2.2 -2.6 -0.6 1.7 0.5 -1.4 -0.4 1.1 0.5
Neuroticism score 0.2 0.5 2.2 0.8 -0.1 -0.7 -0.2 0.3 -1.2 -0.7 -1.2 0.6 -0.8 -0.9 -1.5 0.2 -0.9 -0.3 -1.1 -0.5 0.1 -0.7 -1.1 -0.8 0.4 -0.1 0.1 0.2 -0.2 0.3 0.8
Weight 0.4 1.9 5.3 1.0 1.5 2.0 1.4 1.9 2.3 2.2 1.4 -0.2 1.5 1.5 -0.2 0.3 1.9 2.2 1.8 1.4 0.3 0.8 1.9 1.8 0.8 -1.3 -0.5 0.9 0.2 -0.5 -0.1
Impedance of arm (right) 0.2 1.1 4.3 -0.5 -1.6 -1.8 -1.4 -1.8 -1.4 -2.1 -0.4 -0.4 -0.8 -1.3 0.3 -0.5 -1.0 -1.2 -0.9 -1.1 -0.6 -0.0 -1.4 -1.1 -1.2 0.4 -0.3 -1.1 -0.6 -0.0 -0.2
Arm fat percentage (right) 0.7 2.8 6.9 1.2 0.9 2.3 1.3 1.3 2.5 1.8 2.2 -1.3 2.1 2.3 0.7 -0.3 2.6 2.0 2.0 1.7 -0.2 1.4 1.9 2.4 -0.3 -2.3 -1.5 -0.1 -0.3 -1.4 -1.1
Trunk fat-free mass 0.2 1.3 4.2 0.2 1.6 1.5 1.4 1.8 1.6 2.0 -0.1 0.3 1.1 0.9 -0.4 1.0 1.1 1.4 1.8 1.1 0.6 0.5 1.6 1.2 1.1 -0.5 0.1 1.3 0.5 -0.1 0.3
Hip circumference 0.8 3.5 8.4 0.8 1.8 2.9 2.2 1.4 2.6 2.6 1.9 -1.1 2.3 2.5 0.6 0.1 2.7 2.3 2.5 2.3 -0.4 1.3 2.3 2.6 0.2 -2.2 -1.2 0.4 -0.4 -1.4 -1.1
Time employed in main current job 0.5 0.6 1.5 -0.1 -0.6 -0.0 0.1 -0.8 0.8 0.2 1.0 -1.2 1.2 0.5 0.6 0.3 1.0 0.9 1.2 0.6 -0.3 -0.2 0.3 0.7 -0.6 -1.1 -1.0 -0.6 -0.4 -0.8 -1.1
Alcohol intake versus 10 years previously 0.8 1.2 4.0 1.0 1.1 0.5 0.2 2.0 1.9 1.1 1.0 0.8 0.5 0.5 -0.1 0.0 1.0 1.0 1.1 0.3 1.6 0.9 1.9 1.2 1.5 -0.3 0.6 1.6 1.7 0.5 0.7
Father’s age at death 0.5 0.6 2.9 -0.9 0.6 0.2 0.7 -1.6 -1.7 0.2 -0.4 -0.3 -0.4 -0.0 -0.3 -0.9 -1.0 -0.4 -0.3 0.6 -1.6 0.1 -1.2 -0.9 0.0 0.4 0.2 -0.4 -1.7 -0.1 -0.3
Worrier / anxious feelings 0.5 1.0 4.2 1.5 0.7 0.7 0.8 2.1 0.3 0.6 -1.1 1.2 -0.3 0.1 -1.8 1.6 -0.1 -0.0 0.4 0.3 1.2 -0.2 1.0 0.3 1.3 0.5 1.0 1.5 1.1 0.6 1.1
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 2.9 1.7 0.4 0.1 -0.2 0.3 0.5 -0.2 1.0 0.1 0.3 -0.0 0.1 0.3 0.2 1.2 1.6 -0.3 0.8 -0.1 0.9 0.5 0.8 -0.8 -0.1 1.0 0.9 0.3 0.1
Falls in the last year 0.3 0.4 2.9 0.7 1.7 1.2 1.0 0.3 -0.1 0.7 0.6 0.0 0.2 0.7 1.0 -0.1 -0.0 -0.4 0.7 0.8 -0.3 0.5 0.7 0.0 0.3 -0.1 0.3 0.8 -0.4 -0.1 0.1
Hair/balding pattern: Pattern 3 0.2 0.3 2.0 0.2 -0.2 0.5 0.3 0.4 0.6 0.2 0.4 -0.2 0.3 0.8 -0.4 1.4 0.6 -0.3 1.3 0.5 0.3 0.9 0.7 0.6 -0.4 0.0 -0.1 -0.1 0.3 -0.3 -0.2
Number of live births 1.6 2.3 9.6 1.8 1.7 1.7 1.4 2.6 1.8 1.9 0.9 0.9 0.5 1.4 -0.2 3.1 1.2 1.6 1.6 1.1 1.7 -0.2 2.5 1.0 1.4 0.1 0.8 1.5 1.5 0.3 0.6
Forced expiratory volume in 1-second (FEV1) 0.2 0.6 2.1 1.5 0.3 -0.4 -0.3 0.0 -0.8 -0.7 -1.0 0.8 -1.2 -1.0 -0.8 1.1 -1.2 -0.6 0.3 -0.8 0.4 0.3 -0.3 -1.0 0.0 1.4 0.8 -0.1 0.2 0.8 0.8
Pulse rate 0.9 1.5 7.6 -2.3 0.5 -0.2 0.6 -1.7 -1.0 0.1 1.7 -1.5 0.7 0.4 2.8 -0.4 0.1 1.1 0.0 0.8 -2.0 0.7 -0.9 -0.2 -1.3 -0.9 -1.0 -1.5 -2.1 -1.2 -1.2
Happiness 1.4 1.7 5.2 -0.9 -0.5 -0.9 -0.4 -1.8 -2.1 -1.4 -1.5 -1.0 -0.3 -0.7 -0.8 -1.9 -1.1 -1.4 -1.4 -0.2 -2.1 -1.0 -2.3 -1.0 -1.3 -0.4 -0.9 -1.6 -2.1 -0.7 -0.8
Noisy workplace 1.0 1.3 3.5 1.8 1.2 0.6 0.3 1.8 -0.1 0.3 -0.1 1.9 -1.2 -0.4 -0.8 0.4 -1.0 -0.8 -0.8 -0.4 1.2 -1.0 0.5 -0.6 1.8 1.2 1.7 1.8 1.0 1.5 1.4
Qualifications: A levels/AS levels or equivalent 0.4 0.9 5.1 0.0 2.2 1.2 1.7 0.5 0.1 1.8 0.3 0.5 -0.4 0.3 1.0 2.0 -0.3 0.3 -0.6 0.9 -0.6 0.3 0.7 -0.3 0.8 1.1 1.0 0.8 -0.8 0.4 0.5
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.6 2.8 0.8 0.8 0.3 0.2 1.3 0.3 0.4 -1.7 1.1 -0.4 -0.1 -1.1 0.8 -0.2 -0.9 -0.6 -0.2 0.9 -0.3 0.4 -0.1 0.9 0.8 1.0 1.2 0.8 0.7 1.0
Mouth/teeth dental problems: Dentures 1.0 1.7 7.6 1.0 0.4 1.4 1.1 0.8 1.0 0.8 2.8 -1.0 1.4 1.5 1.8 0.3 1.5 1.7 0.7 1.2 -0.6 1.6 0.8 1.4 -1.1 -1.7 -1.4 -0.7 -0.7 -1.4 -1.2
Asthma 1.2 2.4 10.1 3.2 1.7 0.9 0.3 2.7 0.7 0.7 -0.9 2.2 -1.0 -0.5 -0.9 1.4 -0.6 -0.2 0.1 -0.7 2.0 0.5 1.3 -0.5 2.1 1.6 2.0 2.1 1.7 1.7 2.3
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 2.2 -0.5 -1.2 -1.5 -1.3 -0.5 -0.3 -0.7 -0.6 0.2 -0.6 -0.8 -0.5 -0.9 -0.3 -1.2 -0.5 -0.9 0.7 -0.8 -0.7 -0.5 0.0 0.2 0.0 -0.1 0.8 0.4 0.3
Medication: Cholesterol lowering 1.3 2.0 4.9 -0.7 0.7 1.7 1.8 -0.0 1.2 1.6 1.8 -1.6 1.5 2.2 1.4 -0.5 1.9 0.7 0.2 2.2 -1.6 -0.1 0.9 2.0 -0.9 -1.4 -1.3 -0.8 -1.4 -1.6 -1.8
Depression (self-reported) 0.3 0.4 1.2 -0.6 0.8 0.4 0.8 0.3 0.3 0.4 0.8 -0.7 1.0 0.8 0.6 0.1 0.7 0.6 -0.4 0.9 -0.5 1.1 -0.0 0.8 -0.5 -0.6 -0.6 -0.4 -0.6 -0.9 -0.5
Medication: Lansoprazole 0.8 0.9 4.3 -0.8 -1.0 -1.2 -1.3 -1.3 -0.7 -1.4 -0.9 -0.4 -0.2 -1.0 -1.3 -2.1 -0.6 -0.0 -0.3 -0.9 -0.5 -1.7 -1.0 -0.8 -0.8 0.1 -0.5 -1.0 -0.7 -0.0 -0.2
Prospective memory result 0.8 1.0 4.5 0.1 -0.9 -1.4 -1.5 0.7 0.9 -0.5 -0.5 1.2 -0.2 -1.3 -0.8 0.7 -0.0 0.1 0.2 -1.4 2.1 -0.4 0.7 -0.1 1.3 0.3 0.6 0.9 2.1 1.2 1.0
Lung cancer (father) 0.3 0.3 1.1 -0.6 -0.8 -0.4 -0.5 -0.1 0.7 -0.1 -0.9 -0.6 0.6 0.3 -0.6 0.6 0.8 -0.2 -0.0 0.0 -0.2 0.0 -0.1 0.1 -1.0 -0.6 -0.9 -1.0 -0.4 -0.6 -0.6
Illnesses of mother 0.7 0.8 2.9 -1.0 0.0 -0.6 -0.2 -0.8 -1.1 -0.3 -0.6 0.5 -1.1 -0.9 -0.0 1.0 -1.2 -0.9 -1.2 -0.6 -0.6 -1.4 -1.1 -1.7 -0.2 1.7 0.8 -0.5 -0.8 0.6 0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.2 3.3 1.1 -0.5 -1.1 -0.9 0.1 -0.8 -1.0 -1.7 1.2 -1.6 -1.5 -1.8 1.0 -1.4 -1.2 -0.5 -1.4 0.9 -0.2 -0.7 -1.4 0.1 1.8 1.0 0.1 0.7 1.2 1.1
Pulse wave Arterial Stiffness index 1.0 1.2 3.0 1.1 0.8 1.1 1.3 0.7 1.3 1.4 1.6 -0.8 1.3 1.0 0.6 -0.5 1.4 1.1 1.7 1.1 -0.6 -0.1 1.4 1.5 0.2 -1.7 -0.8 0.1 -0.3 -0.8 -0.6
Impedance of arm (left) 0.2 1.0 2.9 0.1 -0.7 -1.6 -1.1 -1.4 -1.4 -1.7 -0.6 0.2 -1.4 -1.4 0.1 -0.5 -1.4 -1.4 -0.8 -1.1 -0.2 -0.5 -1.0 -1.3 -0.5 1.0 0.5 -0.4 -0.2 0.6 0.3
Arm fat mass (right) 0.8 3.2 8.1 1.5 1.6 2.7 1.7 1.8 2.8 2.4 2.1 -0.9 2.1 2.4 0.5 0.2 2.7 2.4 2.3 1.9 0.1 1.4 2.3 2.6 0.3 -2.0 -1.1 0.6 0.0 -1.1 -0.7
Trunk predicted mass 0.2 1.4 4.4 0.2 1.6 1.6 1.5 1.8 1.6 2.1 0.0 0.4 1.1 1.0 -0.3 1.1 1.1 1.5 1.8 1.2 0.6 0.7 1.7 1.2 1.1 -0.5 0.2 1.3 0.5 -0.1 0.3
Standing height 0.1 1.1 2.8 -1.1 0.9 -0.9 0.0 -0.1 -1.0 0.2 -1.4 1.4 -1.2 -1.6 -1.4 0.3 -1.6 -0.4 -0.1 -0.5 0.0 -0.9 -0.4 -1.5 1.3 1.7 1.5 1.1 -0.1 1.4 1.4
Length of working week for main job 0.5 0.5 2.4 0.7 0.0 0.7 0.6 -0.3 0.2 0.2 1.1 -1.0 0.8 0.6 0.3 -0.0 0.5 1.6 -0.0 0.5 -1.0 1.0 -0.0 0.3 -0.7 -0.9 -0.9 -0.9 -1.0 -0.9 -0.6
Exposure to tobacco smoke at home 2.0 2.3 7.4 1.6 -1.0 1.1 0.4 1.6 2.7 0.9 -0.7 -0.5 1.5 1.6 -1.0 1.9 2.3 1.1 2.7 0.8 2.0 0.2 2.6 2.2 -0.0 -1.4 -0.9 0.4 1.9 -0.7 -0.6
Breastfed as a baby 0.7 0.9 3.2 0.9 1.8 1.7 1.7 0.5 0.5 1.1 0.9 -0.4 0.5 1.4 1.0 0.7 0.8 1.1 0.5 1.5 -0.3 0.1 1.3 1.1 0.1 -0.5 0.1 0.6 -0.3 -0.6 -0.5
Tense / ‘highly strung’ 0.3 0.6 2.4 0.9 0.7 0.7 1.2 -0.5 -1.1 0.4 0.6 -0.5 0.3 0.5 0.6 0.6 -0.4 0.2 -1.4 1.0 -1.3 0.5 -0.9 -0.1 -0.1 -0.6 -0.3 -0.2 -1.5 -0.6 -0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 2.1 3.2 8.3 0.1 0.2 -1.6 -1.9 1.5 -0.4 -0.9 -1.3 2.9 -1.8 -1.8 -2.2 0.7 -1.8 0.3 -1.4 -2.0 2.6 0.3 -0.1 -1.7 2.5 1.8 2.2 2.1 2.5 2.6 2.6
Hair/balding pattern: Pattern 4 0.6 1.5 4.0 -0.2 -0.6 -0.6 -0.2 -1.6 -1.1 -1.0 1.4 -1.5 0.5 -0.2 1.6 -1.6 -0.0 1.5 -1.5 0.0 -1.8 0.7 -1.8 -0.0 -1.5 -1.2 -1.4 -2.0 -1.7 -1.2 -1.6
Birth weight of first child 0.5 0.9 2.8 0.1 0.1 -1.1 -1.0 -1.0 -1.4 -1.1 0.1 0.9 -1.4 -1.3 0.0 0.1 -1.7 -0.7 -0.0 -1.1 0.2 -0.7 -0.6 -1.4 0.6 1.3 1.1 0.9 0.3 1.3 0.9
Peak expiratory flow (PEF) 0.2 0.5 3.1 1.8 -0.1 0.2 -0.1 0.5 0.6 -0.2 -1.5 0.3 -0.2 -0.1 -1.4 0.1 0.2 -0.9 1.4 -0.4 1.0 -0.6 0.8 0.6 0.1 -0.0 0.0 0.2 0.9 0.2 0.3
Pulse wave reflection index 0.3 0.4 1.6 0.7 0.8 0.8 0.8 1.3 0.9 1.2 0.5 0.4 0.5 0.6 -0.2 0.1 0.5 0.4 0.9 0.5 0.5 0.0 1.0 0.5 0.9 -0.1 0.2 0.7 0.5 0.2 0.5
Ever highly irritable/argumentative for 2 days 0.5 0.6 3.0 -0.5 -0.3 0.5 0.3 0.8 1.5 0.8 0.1 -0.2 1.1 0.9 -0.3 0.2 1.1 0.8 1.7 0.7 0.5 0.2 1.1 1.2 0.4 -0.8 -0.2 0.5 0.7 -0.3 -0.4
Loud music exposure frequency 0.5 0.6 2.1 -0.2 0.9 0.7 0.6 0.1 -1.3 0.3 -0.7 0.8 -0.5 0.0 -0.7 0.1 -1.4 -0.6 -0.2 0.3 -0.4 -0.6 -0.5 -1.0 1.1 0.7 1.1 1.0 -0.8 0.6 1.0
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 2.3 0.4 1.5 1.1 1.3 -0.3 -0.7 1.0 -0.8 0.4 -0.8 0.1 -0.5 0.0 -0.9 -0.7 0.5 0.6 -0.9 -0.2 0.6 -0.7 0.7 1.1 1.0 0.3 -1.1 0.5 0.5
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 7.3 -1.2 -2.7 -0.9 -1.3 0.6 0.5 -1.0 -0.7 -0.3 0.7 -0.5 -1.5 -0.9 0.6 -0.5 -0.6 -0.9 0.3 -0.4 -0.9 0.1 -0.8 -0.9 -1.3 -1.1 0.4 -0.5 -0.4
Blood clot in the leg (DVT) 0.7 1.0 4.5 1.0 2.1 1.4 1.7 -0.3 -0.5 0.8 1.2 -0.9 0.4 0.8 1.5 0.2 0.2 0.1 0.5 1.2 -1.7 0.5 0.0 0.2 -0.4 -0.7 -0.4 -0.3 -1.9 -0.8 -0.5
Medication: Paracetamol 0.5 0.8 3.7 1.2 1.0 0.4 0.4 0.1 -1.1 -0.1 -0.7 0.5 -1.0 -0.2 -1.1 -1.9 -0.9 -1.9 0.1 -0.1 -0.4 -1.7 0.0 -0.5 0.6 0.3 0.8 0.8 -0.4 0.5 0.7
Headache pain in last month 2.0 3.5 9.4 3.1 0.7 -1.1 -1.3 0.7 -0.5 -1.0 -1.9 2.6 -2.5 -1.8 -2.1 1.4 -1.8 -0.7 0.4 -2.0 2.3 -0.7 1.0 -1.5 2.1 2.5 2.6 1.9 2.5 2.7 2.5
Medication for cholesterol, blood pressure or diabetes 0.7 1.1 3.3 -1.1 -1.5 -1.5 -1.4 -1.1 -1.4 -1.8 -1.3 0.2 -0.7 -1.4 -0.8 -0.0 -1.2 -1.0 -1.0 -1.4 0.2 0.4 -1.8 -1.3 -0.6 0.5 -0.0 -0.6 0.1 0.3 0.5
Glaucoma (self-reported) 0.8 0.9 3.3 1.6 1.3 0.6 0.4 1.0 0.4 0.7 -0.2 1.2 -0.8 0.1 -0.2 1.0 -0.3 0.2 -0.1 -0.1 1.2 -0.3 1.2 -0.4 1.6 0.9 1.5 1.8 1.3 1.2 1.2
Gout (self-reported) 0.7 0.9 3.6 -0.6 -0.4 0.1 0.3 -1.1 -0.0 0.0 1.8 -1.4 0.9 0.9 1.9 -0.0 0.8 0.7 0.1 0.7 -1.0 0.4 -0.1 0.7 -1.0 -1.5 -1.3 -1.1 -0.7 -1.2 -1.5
Hypothyroidism/myxoedema (self-reported) 2.2 4.3 10.8 1.1 1.1 3.1 2.6 1.0 1.5 1.9 2.1 -2.1 2.7 3.3 2.1 0.3 2.6 1.6 1.6 2.9 -1.1 2.5 1.2 2.8 -1.3 -2.8 -2.1 -0.6 -1.2 -2.6 -2.2
Medication: Amlodipine 0.4 0.5 1.4 0.9 -1.1 -1.1 -1.1 1.2 0.6 -0.8 -0.8 0.7 -0.4 -1.0 -1.0 -0.6 0.1 -0.0 0.2 -1.0 1.2 -0.1 0.2 0.0 -0.2 0.3 -0.1 -0.1 1.2 0.4 0.6
Medication: Ventolin 100micrograms inhaler 0.4 0.5 2.0 1.1 0.3 -0.1 -0.6 1.3 0.3 -0.4 -0.4 1.0 -0.6 -0.2 -0.4 0.6 -0.3 0.2 0.1 -0.7 1.4 -0.6 0.5 -0.1 0.5 0.8 0.8 0.7 1.3 0.7 0.8
Birth weight 1.4 3.0 7.0 -1.0 -1.3 -2.2 -2.3 0.7 -0.5 -1.4 -0.9 2.3 -2.1 -2.6 -1.9 -1.1 -1.9 -0.8 -1.6 -2.6 1.5 -1.4 -0.8 -2.1 1.0 2.3 1.6 0.8 1.5 2.2 2.3
Chronic bronchitis/emphysema (mother) 0.7 0.8 4.9 -0.3 0.6 0.7 0.9 -1.2 -1.0 0.1 0.9 -1.1 0.0 0.5 0.9 -0.8 -0.3 -0.3 0.2 0.7 -2.2 0.0 -0.3 -0.2 -1.1 -0.2 -0.6 -1.0 -2.0 -0.7 -0.9
High blood pressure (siblings) 1.9 2.7 7.2 0.8 1.1 2.2 2.1 1.8 2.5 2.2 0.2 -1.0 2.3 2.2 0.4 1.4 2.7 1.6 1.1 2.0 0.4 -0.2 2.4 2.7 0.1 -2.0 -1.0 0.7 0.3 -1.4 -1.2
Forced vital capacity (FVC), Best measure 0.1 0.5 2.2 0.2 0.2 -0.4 -0.0 -0.0 -0.6 -0.1 -0.8 0.8 -0.8 -0.8 -0.9 1.1 -1.0 -0.3 -0.2 -0.5 0.1 0.6 -0.5 -0.9 0.3 1.5 0.9 0.2 0.1 0.7 0.8
Body fat percentage 0.5 1.9 5.5 1.3 0.8 1.9 0.8 1.3 2.3 1.6 2.1 -0.6 1.4 1.8 0.2 -0.3 2.1 1.9 2.0 1.1 0.2 1.2 2.0 1.8 0.2 -1.6 -0.9 0.3 0.2 -0.7 -0.5
Leg fat percentage (right) 0.6 2.2 6.9 2.3 0.8 2.3 1.0 2.0 2.6 1.9 1.8 -0.2 1.2 1.8 -0.7 0.3 2.0 1.6 2.1 1.0 0.7 0.8 2.4 1.8 0.8 -1.2 -0.4 0.8 0.7 -0.3 0.0
Arm fat-free mass (right) 0.3 1.5 5.1 0.2 1.8 1.7 1.5 1.8 1.7 2.3 0.2 0.5 1.0 1.0 -0.4 0.7 1.1 1.6 1.8 1.2 0.6 0.3 1.8 1.2 1.4 -0.5 0.4 1.6 0.6 0.1 0.5
Exposure to tobacco smoke outside home 0.6 0.8 2.5 1.2 -1.2 0.1 -0.4 -0.9 -0.9 -1.2 0.1 -1.1 -0.0 0.1 -0.3 -1.4 -0.2 -0.8 -0.5 -0.2 -1.2 -0.8 -1.0 -0.1 -1.5 -0.5 -1.0 -1.6 -1.1 -0.8 -0.9
Comparative body size at age 10 0.4 1.1 3.1 1.5 1.2 1.2 0.8 1.8 0.6 1.2 -0.3 1.2 -0.0 0.5 -1.5 0.3 -0.1 0.9 0.9 0.3 1.0 -0.6 1.4 0.1 1.7 0.4 1.0 1.6 0.8 0.9 1.4
Number of full brothers 0.8 0.9 4.1 1.6 1.8 1.0 1.1 1.1 -0.2 0.8 1.0 0.9 -0.4 0.1 0.7 2.0 -0.6 1.4 0.8 0.3 0.2 1.3 0.6 -0.3 0.9 0.9 1.1 0.8 -0.1 0.6 1.0
Worry too long after embarrassment 0.4 0.7 4.6 -0.1 -0.8 -0.9 -0.2 0.2 -0.9 -0.5 -2.2 0.5 -0.7 -1.1 -1.9 0.3 -0.7 -1.3 -0.5 -0.5 0.3 -1.4 -0.9 -0.7 0.0 0.1 0.0 -0.3 -0.1 0.2 0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 2.5 3.3 9.4 3.0 1.1 -0.2 -0.6 2.3 0.5 0.3 -0.3 2.8 -1.5 -1.1 -1.7 0.9 -1.2 0.0 -0.9 -1.4 2.7 0.2 1.2 -1.1 3.1 1.6 2.3 2.8 2.5 2.5 2.8
Wheeze or whistling in the chest in last year 0.8 1.4 5.2 2.3 1.5 1.5 1.1 1.9 1.4 1.6 0.2 0.8 0.1 1.1 -0.5 1.9 0.5 0.7 1.2 0.6 1.1 0.1 1.9 0.5 1.2 0.6 1.0 1.2 0.9 0.6 0.9
Number of children fathered 0.4 0.4 2.2 0.4 0.9 0.2 0.4 -0.8 -1.5 -0.2 0.2 0.2 -0.8 -0.1 0.2 0.1 -1.3 -0.6 1.1 0.1 -0.6 0.3 0.0 -1.1 0.2 0.9 0.7 -0.0 -0.7 0.4 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.0 3.7 0.0 0.8 -0.6 -0.1 -0.1 -1.6 -0.3 -0.2 1.1 -1.5 -0.9 0.4 -0.0 -1.7 -1.0 -1.9 -0.5 -0.2 -1.4 -0.9 -1.2 1.1 1.3 1.3 0.9 0.1 1.1 1.1
Age at first live birth 0.5 0.9 2.0 1.4 -0.1 -1.0 -1.2 0.1 -0.3 -1.1 -1.0 1.1 -1.4 -1.3 -1.1 -0.8 -0.9 -1.2 -0.1 -1.3 0.9 0.1 -0.2 -0.4 0.5 1.1 1.0 0.7 1.1 1.1 0.9
Pulse wave peak to peak time 1.1 1.3 3.7 -1.1 -0.6 -1.1 -1.3 -0.4 -1.2 -1.3 -1.9 1.1 -1.4 -1.2 -1.0 0.8 -1.5 -1.2 -1.5 -1.2 0.8 0.0 -1.1 -1.6 0.1 1.9 1.1 0.2 0.6 1.1 0.9
Health satisfaction 0.9 1.2 3.2 -0.1 0.2 0.6 0.5 -0.7 0.5 0.3 1.5 -1.6 1.7 1.1 1.6 -0.2 1.0 1.6 0.7 1.1 -1.3 0.5 -0.0 1.2 -0.8 -1.8 -1.5 -0.8 -1.1 -1.3 -1.4
Shortness of breath walking on level ground 1.0 1.2 4.5 -0.9 0.7 0.9 1.2 -1.4 -0.8 0.4 1.1 -1.5 0.7 0.9 1.2 -0.1 0.3 0.6 0.6 1.4 -1.9 -0.4 -0.3 0.3 -1.1 -1.1 -1.1 -1.2 -2.1 -1.3 -1.6
Qualifications: College or University degree 0.3 1.0 3.6 -1.3 0.5 -1.0 -0.3 -0.5 -1.1 -0.3 -0.7 1.0 -1.4 -1.2 -1.3 -0.9 -1.4 -0.8 -1.9 -0.6 -0.0 -0.5 -1.2 -1.3 0.5 1.6 1.1 0.3 -0.1 0.9 1.0
Eye problems/disorders: None of the above 0.5 0.6 1.4 -0.9 0.4 1.1 1.1 0.7 -0.2 0.6 0.7 -0.5 0.7 1.1 0.6 -0.4 0.4 -0.3 -0.1 1.2 -0.9 -0.9 -0.4 0.7 -0.8 -0.6 -0.7 -0.4 -1.1 -1.1 -0.9
Mouth/teeth dental problems: Loose teeth 0.4 0.4 1.2 -0.9 -0.6 0.0 -0.0 -0.3 0.3 -0.2 0.3 -0.9 0.9 0.6 0.3 0.2 0.8 -0.0 0.6 0.4 -0.3 1.0 -0.0 0.6 -0.9 -1.1 -1.1 -0.9 -0.1 -0.9 -0.9
Emphysema/chronic bronchitis 1.1 1.2 4.0 0.7 0.9 1.0 0.9 1.6 0.5 1.5 0.1 1.3 0.0 0.7 -0.1 2.0 -0.2 0.8 0.8 0.5 1.4 0.3 1.4 0.1 1.9 0.7 1.3 2.0 1.4 1.0 0.9
Medication for pain relief, constipation, heartburn 0.4 0.7 3.4 -0.5 -0.4 -1.2 -1.1 -0.4 -0.6 -1.2 0.5 0.6 -0.7 -1.1 1.0 1.9 -1.0 0.7 -0.3 -1.1 0.4 1.4 -0.9 -1.1 -0.2 0.9 0.4 -0.3 0.4 0.6 0.5
Neck or shoulder pain in last month 1.5 2.2 6.9 -0.7 -2.0 -2.1 -2.3 -0.6 -0.4 -1.6 -2.3 1.1 -1.5 -1.7 -2.6 -0.0 -1.1 -2.1 0.5 -2.1 1.2 -1.6 -0.3 -1.5 0.3 1.2 0.7 0.3 1.6 1.5 1.1
Medication: Blood pressure 0.5 0.9 4.2 1.8 1.3 0.9 0.9 1.3 1.5 1.4 0.8 0.2 0.4 0.8 0.1 0.3 1.1 1.2 1.4 0.8 0.5 -0.1 2.0 1.0 0.9 -0.2 0.2 0.6 0.6 0.2 0.1
Angina (self-reported) 0.5 0.7 3.0 1.7 1.2 1.3 1.3 0.2 0.3 0.9 1.2 -0.3 0.3 1.1 0.7 1.3 0.2 0.9 0.4 1.1 -0.5 0.5 1.1 0.5 0.2 0.1 0.2 0.4 -0.6 -0.2 -0.2
Migraine (self-reported) 0.3 0.4 1.5 -0.3 0.2 0.1 -0.2 0.6 0.8 0.1 -0.6 0.5 0.4 0.2 -0.1 0.8 0.5 -0.2 1.0 0.2 1.0 -0.2 0.9 0.5 0.7 0.0 0.5 1.1 1.2 0.3 0.6
Medication: Ibuprofen 1.1 1.4 3.7 0.3 -1.0 -1.9 -1.8 -0.2 -0.5 -1.2 -1.2 1.1 -1.4 -1.5 -1.3 -0.4 -1.0 -1.5 -0.1 -1.7 1.5 -1.2 -0.4 -1.2 0.7 1.0 0.8 0.5 1.5 1.3 1.1
Medication: Allopurinol 0.5 0.7 3.4 -0.3 -0.5 0.2 0.2 -1.1 0.5 0.3 1.8 -1.2 0.8 0.7 1.5 0.1 0.9 1.2 -0.4 0.4 -0.7 0.5 0.3 0.6 -0.5 -1.2 -0.9 -0.7 -0.2 -0.7 -1.4
Medication: Omeprazole 0.3 0.4 3.0 1.7 0.7 0.8 0.7 0.3 -0.2 0.5 -0.4 0.3 -0.4 0.1 -1.1 0.3 -0.3 -0.6 0.1 0.1 -0.2 -1.1 0.3 -0.1 0.5 0.5 0.6 0.4 -0.3 0.4 -0.0
Medication: Seretide 50 evohaler 0.8 0.9 2.9 0.9 0.4 1.3 1.1 1.7 1.6 1.4 1.0 0.3 0.8 0.9 0.6 1.2 1.1 0.6 0.9 0.6 1.0 0.8 1.3 1.3 0.7 -0.1 0.3 0.8 0.7 -0.1 0.1
Mean time to correctly identify matches 0.9 1.8 4.0 -0.7 -0.1 -1.3 -1.0 0.4 -1.2 -0.5 0.3 2.0 -1.6 -1.5 -0.7 0.2 -1.9 -0.4 -2.0 -1.3 1.1 -1.0 -0.5 -1.8 1.8 1.7 1.8 1.4 1.0 1.9 1.9
Heart disease (mother) 0.5 0.6 2.6 1.2 1.3 0.4 0.1 0.6 0.5 0.4 1.1 0.7 0.2 0.1 0.1 -1.3 -0.1 0.5 0.7 0.1 0.8 0.9 0.9 0.7 1.4 -0.2 0.8 1.6 0.8 0.6 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.2 1.5 4.8 -0.4 -1.9 -0.2 -0.5 0.2 1.0 -0.5 0.1 -1.5 1.3 0.6 -0.6 -1.6 1.7 -0.3 1.2 0.2 -0.4 -1.1 -0.0 1.3 -1.9 -2.0 -2.2 -1.9 -0.2 -1.6 -1.5
Whole body fat mass 0.6 2.6 6.3 1.0 1.3 2.3 1.4 1.5 2.5 2.1 2.1 -0.8 1.8 2.1 0.3 -0.1 2.3 2.4 2.4 1.6 -0.1 1.2 2.1 2.1 0.3 -1.8 -1.0 0.4 -0.1 -0.9 -0.7
Leg fat mass (right) 0.6 2.2 6.4 1.5 1.2 2.4 1.4 1.7 2.5 2.2 1.6 -0.4 1.5 2.0 -0.4 0.3 2.1 1.9 2.1 1.4 0.3 0.7 2.3 1.9 0.7 -1.5 -0.6 0.7 0.3 -0.5 -0.2
Arm predicted mass (right) 0.2 1.2 4.0 -0.3 1.4 1.4 1.3 1.7 1.6 2.0 0.1 0.3 1.1 0.9 -0.4 0.5 1.2 1.6 1.7 1.1 0.5 0.3 1.5 1.2 1.1 -0.7 0.1 1.2 0.4 -0.1 0.3
Pulse rate, automated reading 0.8 2.5 10.1 -2.0 1.4 -0.9 0.4 -2.4 -1.9 -0.3 2.1 -1.5 -0.1 -0.2 3.2 -0.4 -0.6 1.6 -1.5 0.6 -2.9 -0.7 -1.8 -1.0 -1.6 -0.3 -0.8 -2.0 -2.9 -1.0 -1.4
Alcohol intake frequency. 0.2 0.5 2.1 0.3 -0.0 -0.2 -0.4 1.3 1.2 -0.1 -0.1 0.5 0.3 0.0 -0.1 0.7 0.7 0.2 1.2 -0.1 1.4 0.6 1.0 0.8 0.3 0.0 0.1 0.6 1.4 0.2 0.4
Comparative height size at age 10 0.1 0.3 3.4 -1.8 -0.1 -0.6 -0.2 0.5 0.8 0.4 -0.3 0.4 0.2 -0.3 -0.2 0.9 0.3 0.1 0.5 0.1 0.6 -0.9 0.6 0.3 0.4 0.2 0.1 0.5 0.7 0.3 0.2
Number of full sisters 0.9 1.1 3.1 -0.8 -1.0 -0.8 -1.1 -0.7 0.7 -1.4 0.9 -1.3 1.3 0.2 1.2 0.1 0.9 1.2 1.0 -0.2 -0.3 1.4 -0.3 0.8 -1.7 -1.3 -1.8 -1.5 -0.3 -1.1 -1.2
Suffer from ‘nerves’ 0.2 0.3 2.5 0.6 -1.6 -0.4 -0.7 0.3 0.0 -0.7 -0.6 -0.1 0.2 0.1 -1.0 -0.4 0.3 -0.1 -0.5 -0.4 0.7 -0.3 -0.4 0.4 -0.0 -1.1 -0.7 0.2 0.6 -0.3 -0.2
Overall health rating 0.6 1.3 3.8 -0.2 -1.4 -0.3 -0.6 -0.7 -0.0 -1.1 1.2 -1.5 1.3 0.5 1.2 -0.8 0.7 1.2 -0.2 0.2 -1.0 1.6 -1.0 0.8 -1.6 -1.8 -1.9 -1.3 -0.9 -1.4 -1.3
Chest pain or discomfort 2.1 3.1 7.8 2.4 1.6 2.5 2.0 2.0 2.6 2.3 1.0 -0.4 1.8 2.2 0.4 1.2 2.2 2.3 2.1 2.0 1.0 0.9 2.8 2.5 1.0 -1.4 -0.3 1.3 0.8 -0.6 -0.6
Had major operations 0.6 0.7 2.6 0.6 -0.8 0.2 -0.1 -1.0 0.1 -0.5 0.0 -1.4 0.5 0.8 0.4 -0.2 0.9 -0.7 0.7 0.2 -0.5 0.2 0.1 0.5 -1.6 -1.1 -1.4 -1.5 -0.5 -1.1 -1.2
Age at last live birth 0.7 1.0 4.4 2.1 -0.2 -1.1 -1.3 0.8 0.1 -1.2 -1.0 1.3 -1.2 -1.4 -1.2 0.5 -0.8 -0.3 0.4 -1.4 1.3 0.8 0.1 -0.6 0.5 1.1 0.9 0.4 1.3 1.1 1.0
Family relationship satisfaction 0.6 0.8 2.6 -1.1 1.2 -0.1 0.2 -0.6 -1.2 0.3 -0.3 0.8 -0.9 -0.3 -0.1 0.2 -1.5 -0.4 -1.6 0.1 -0.6 -1.0 -0.8 -1.2 1.0 1.2 1.2 1.0 -0.7 0.9 0.7
Leg pain on walking 4.5 5.7 15.4 -0.8 -0.3 1.9 1.5 0.3 2.2 1.3 2.8 -2.9 3.7 3.0 2.7 -0.1 3.5 3.4 0.9 2.6 -1.1 1.4 0.9 3.2 -1.9 -3.9 -3.3 -1.5 -1.0 -3.2 -3.3
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.9 3.0 -1.2 -1.6 -0.3 -0.7 0.1 0.5 -0.8 0.2 -1.1 0.9 0.7 1.3 0.3 1.2 -0.5 0.8 0.2 0.1 -0.4 -0.1 0.9 -1.7 -1.3 -1.5 -1.2 0.1 -1.3 -1.2
Commuting to job workplace: Car/motor vehicle 1.0 1.2 10.5 0.1 -2.4 -1.0 -1.0 0.2 0.4 -0.7 -2.4 0.6 -0.7 -0.9 -3.2 0.1 -0.1 -1.0 -0.0 -0.9 0.9 -1.1 0.0 -0.1 0.1 0.5 0.2 -0.1 1.0 0.6 0.3
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 2.0 0.2 -0.6 0.1 -0.1 -0.3 1.1 -0.0 0.6 -0.9 0.8 0.5 0.8 -1.0 1.3 0.3 0.5 0.3 0.1 0.7 0.4 1.3 -0.5 -1.4 -1.1 -0.4 0.3 -0.8 -1.0
Medication: Aspirin 1.8 2.4 6.2 0.0 2.0 2.3 2.4 0.1 1.1 2.3 2.0 -1.3 1.8 2.2 1.6 -0.8 1.6 1.8 0.9 2.5 -1.3 0.5 1.7 1.8 0.2 -1.6 -0.8 0.3 -1.4 -1.2 -1.2
Supplements: Vitamin C 1.2 1.4 5.5 1.7 2.3 1.2 1.2 0.8 -0.2 1.4 0.2 1.2 -0.6 0.5 0.2 1.4 -0.9 0.0 1.2 0.5 0.7 -0.6 1.4 -0.3 1.9 1.2 1.9 2.1 0.5 1.2 0.9
Knee pain experienced in last month 0.4 0.6 2.7 1.1 0.5 1.3 0.9 0.8 0.7 1.3 0.5 0.1 0.4 0.9 -0.4 1.6 0.5 0.7 0.1 0.6 0.1 -1.1 0.9 0.5 0.7 -0.5 0.1 0.9 0.1 0.0 0.0
Hypertension (Self-reported) 0.4 1.2 4.4 2.1 1.3 0.9 0.8 1.9 2.0 1.2 0.1 -0.2 0.8 0.7 -0.4 -0.5 1.8 1.2 0.8 0.7 0.6 -1.0 2.1 1.5 0.5 -1.0 -0.4 0.4 0.7 -0.3 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.4 1.7 4.9 1.4 0.7 -0.9 -0.8 -1.6 -1.8 -0.9 -1.7 0.7 -1.9 -1.6 -1.2 -0.4 -2.1 -0.9 0.6 -1.3 -0.7 -2.2 -0.5 -2.1 0.5 1.6 1.2 0.1 -0.5 1.5 1.0
Illnesses of father: Heart disease 1.3 1.8 5.5 -0.6 0.7 1.5 1.6 -0.5 -0.3 0.6 1.9 -1.7 1.4 1.2 1.9 -0.9 0.7 0.9 -0.1 1.6 -2.3 1.5 -0.9 1.1 -1.3 -1.5 -1.3 -1.1 -2.3 -1.9 -1.2
Illnesses of siblings: Diabetes 2.0 2.4 5.2 1.5 1.2 2.0 1.6 0.5 1.6 1.1 1.9 -1.3 1.6 2.1 2.3 1.3 2.0 1.9 1.9 1.9 -0.1 2.1 1.6 2.2 -0.7 -1.4 -1.0 -0.3 0.0 -1.5 -1.2
Smoking status: Previous 0.5 0.7 4.0 0.8 -0.2 0.6 0.2 1.4 2.0 1.1 -0.0 0.5 0.8 0.5 -0.5 -0.2 1.2 0.4 0.1 0.2 1.1 -0.0 1.2 1.0 0.9 -0.5 0.0 1.1 1.2 0.2 0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 1.9 -0.8 -0.4 -0.6 -0.0 -1.4 -1.2 -0.6 -0.6 -0.4 -0.4 -0.6 -0.7 -0.8 -0.9 -0.9 -0.8 -0.2 -1.3 -1.1 -1.3 -0.7 -0.6 0.3 -0.1 -0.6 -1.1 -0.1 -0.2
Whole body fat-free mass 0.2 1.3 4.2 -0.0 1.5 1.5 1.4 1.8 1.7 2.0 0.1 0.2 1.1 1.0 -0.3 0.7 1.3 1.6 1.7 1.2 0.5 0.5 1.6 1.3 1.0 -0.7 0.0 1.2 0.4 -0.2 0.2
Leg fat-free mass (right) 0.2 0.9 3.2 -0.5 1.3 1.2 1.3 1.3 1.4 1.8 0.3 -0.1 1.2 0.9 -0.0 0.2 1.2 1.4 1.5 1.2 0.1 0.1 1.1 1.2 0.6 -0.9 -0.3 0.7 -0.0 -0.4 -0.1
Arm fat percentage (left) 0.7 2.7 6.3 1.4 1.2 2.4 1.4 1.3 2.5 1.9 2.1 -1.1 1.9 2.3 0.7 -0.3 2.5 1.9 2.1 1.7 -0.1 1.2 2.0 2.3 -0.1 -2.2 -1.3 0.1 -0.2 -1.2 -1.0
Average weekly red wine intake 0.2 0.3 2.2 -0.8 0.0 0.2 0.1 -0.4 -0.9 -0.1 0.7 -0.2 -0.1 0.2 0.0 -1.5 -0.5 -0.2 -1.0 0.2 -1.0 0.3 -0.8 -0.4 -0.4 -0.1 -0.4 -0.5 -0.8 -0.2 0.3
Handedness (chirality/laterality): Left-handed 1.5 1.8 7.1 -2.5 -0.8 0.0 0.3 -1.8 -1.6 -0.5 0.5 -1.4 0.4 0.3 0.6 -1.7 -0.4 -0.4 -1.3 0.7 -2.7 0.7 -1.9 -0.2 -1.8 -0.4 -1.2 -2.1 -2.6 -1.3 -1.1
Mood swings 0.2 0.3 1.5 0.3 0.7 0.8 0.7 0.7 0.1 0.4 0.5 -0.2 0.5 0.7 0.5 1.0 0.4 1.2 0.1 0.7 -0.2 0.8 0.2 0.5 0.1 -0.9 -0.4 0.0 -0.3 -0.5 -0.1
Loneliness, isolation 0.6 0.9 2.8 0.2 0.3 -0.7 -0.2 0.0 -1.0 -0.2 -0.4 1.0 -1.2 -1.2 -1.7 -0.1 -1.4 -0.1 -1.6 -0.8 -0.1 -0.4 -0.5 -1.3 1.1 1.2 1.1 0.6 -0.1 1.2 1.4
Long-standing illness, disability or infirmity 0.6 0.9 3.4 1.5 1.4 1.4 1.2 1.7 0.8 1.4 0.2 0.6 0.4 0.9 -0.6 0.6 0.4 0.5 0.2 0.8 0.5 -0.2 1.3 0.5 1.4 0.1 0.8 1.8 0.6 0.4 0.7
Ever had bowel cancer screening 1.2 1.4 5.4 1.5 2.3 0.9 1.2 0.7 -1.0 1.0 1.2 1.3 -1.2 -0.3 -0.7 -0.2 -1.3 -0.1 -2.3 0.2 -0.4 -1.4 -0.1 -0.7 1.4 1.5 1.7 1.2 -0.6 1.1 1.4
Diabetes diagnosed by doctor 3.5 5.7 11.8 0.1 0.3 2.5 2.1 0.5 2.3 1.7 2.9 -2.8 3.1 3.3 3.1 0.7 3.4 2.6 1.7 2.9 -1.1 3.0 1.8 3.3 -1.6 -3.4 -2.6 -1.1 -0.8 -2.9 -2.8
Ever had stillbirth, spontaneous miscarriage or termination 2.6 2.7 5.8 1.7 0.4 -1.8 -1.8 -0.2 -1.3 -1.6 -1.8 1.9 -2.4 -2.4 -1.3 0.7 -2.2 -1.8 0.1 -2.4 1.0 -0.7 -0.5 -2.3 1.1 2.2 1.9 1.1 1.1 2.1 2.2
Friendships satisfaction 0.6 0.7 3.9 -2.0 -0.3 -0.1 0.5 -0.9 -0.9 0.3 -1.1 -0.4 0.2 0.1 -0.2 -0.9 -0.4 -1.3 -1.8 0.6 -1.1 -1.5 -1.3 -0.3 -0.3 -0.3 -0.3 -0.3 -1.2 -0.5 -0.4
Qualifications: nursing, teaching 0.8 1.3 2.9 -0.0 1.5 -0.2 0.1 -0.1 -1.2 0.3 -0.8 1.4 -1.6 -0.7 -1.3 -0.4 -1.6 -1.7 -1.2 -0.4 -0.1 -1.5 -0.1 -1.7 1.3 1.6 1.6 1.3 -0.2 1.5 1.1
Commuting to job workplace: Walk 1.4 1.5 4.1 1.0 1.5 0.2 0.1 1.2 0.7 0.9 -1.4 1.7 -0.7 -0.6 -1.1 1.0 -0.6 -0.0 1.0 -0.5 1.7 -0.5 1.6 -0.6 2.0 1.5 1.8 1.9 1.5 1.7 1.8
Eye problems/disorders: Cataract 0.3 0.3 2.8 -1.2 -1.1 -0.7 -0.5 -1.0 -0.1 -0.3 0.1 -0.4 0.5 -0.2 -0.0 -0.2 0.2 0.5 0.4 -0.1 0.3 1.7 -0.2 0.1 0.0 -0.8 -0.5 -0.1 0.4 -0.2 -0.3
Mouth/teeth dental problems: Mouth ulcers 1.1 1.8 5.3 0.2 0.7 -1.4 -1.3 -0.6 -1.3 -0.7 -0.6 1.7 -1.7 -1.9 -0.8 0.1 -2.2 -0.7 -0.6 -1.8 0.9 -0.0 -0.7 -2.3 1.5 1.9 1.8 1.0 0.8 2.1 1.5
Medication for cholesterol 1.1 1.6 5.2 -0.2 0.8 -1.0 -0.9 -0.7 -1.2 -0.8 -0.8 1.6 -2.0 -1.4 0.1 0.9 -2.0 -0.3 0.1 -1.4 1.3 -0.9 -0.4 -2.0 1.2 2.3 2.0 1.1 1.1 1.8 1.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 2.6 -0.1 0.8 0.5 0.7 -1.2 -0.9 0.2 0.4 -0.8 0.3 0.6 1.2 -1.1 -0.2 -0.0 -0.7 0.8 -1.6 0.0 -0.7 0.0 -0.5 -0.5 -0.5 -0.4 -1.4 -0.6 -0.5
Back pain experienced in last month 0.4 0.6 2.3 0.2 -0.6 -0.1 -0.7 1.0 0.9 0.3 -0.5 0.8 0.0 -0.3 -0.6 1.4 0.1 -0.4 0.2 -0.7 1.5 -0.2 0.7 -0.3 1.0 0.3 0.5 1.4 1.5 0.9 0.8
Mineral and other dietary supplements 2.2 2.9 10.9 -1.3 -2.4 -2.7 -2.0 -2.3 -2.4 -2.8 -0.9 -0.5 -1.1 -2.0 0.3 -0.9 -1.6 -0.4 -1.9 -1.7 -1.0 -0.3 -3.3 -1.9 -1.9 0.5 -0.8 -2.7 -1.2 -0.2 -0.2
Breast cancer (self-reported) 1.5 1.8 4.8 -1.3 -1.6 0.6 0.3 -0.7 0.9 0.1 0.7 -2.0 1.9 1.4 0.8 -0.5 1.8 0.9 -0.2 1.0 -0.9 -0.1 -0.3 1.7 -1.7 -2.2 -2.2 -1.4 -0.7 -1.9 -2.1
Asthma (self-reported) 1.4 2.8 11.8 3.4 1.8 1.1 0.6 3.0 1.0 1.0 -0.7 2.4 -0.9 -0.3 -1.0 1.5 -0.5 -0.2 0.5 -0.5 2.2 0.5 1.6 -0.3 2.3 1.6 2.2 2.4 1.9 1.7 2.3
Osteoporosis (self-reported) 1.1 1.3 2.8 0.1 -0.5 -1.5 -1.3 0.8 -0.3 -1.1 -1.1 1.5 -1.6 -1.5 -1.2 0.6 -1.0 -1.4 -0.4 -1.5 1.2 -1.2 -0.3 -1.0 0.7 1.7 1.3 0.8 1.5 1.4 1.4
Osteoarthritis (self-reported) 0.8 1.0 7.7 2.8 0.5 1.0 0.1 1.6 1.1 0.9 0.1 1.0 -0.0 0.4 -0.5 1.1 0.4 1.1 0.4 -0.2 1.0 0.3 1.2 0.6 1.5 0.0 0.6 1.5 1.3 0.8 0.6
Medication: Aspirin 1.4 1.8 4.8 -0.3 1.7 1.9 2.0 0.1 0.7 1.8 1.8 -1.2 1.5 1.8 1.4 -1.1 1.3 1.5 0.5 2.2 -1.3 0.4 1.2 1.5 0.1 -1.6 -0.8 0.2 -1.3 -1.2 -1.2
Medication: Gliclazide 1.2 1.4 5.0 2.0 1.5 1.3 1.1 2.2 1.1 1.5 1.3 1.2 -0.0 0.6 0.1 0.8 0.4 0.2 0.6 0.4 1.1 0.8 1.8 0.6 1.9 0.2 1.1 1.7 1.4 0.8 1.0
Illnesses of father: None of the above (group 1) 0.6 0.7 3.6 0.3 -0.7 -0.5 -0.8 0.5 1.2 0.2 -0.5 0.7 -0.1 -0.0 -0.8 1.1 0.4 -0.4 1.2 -0.5 1.9 -0.1 1.4 0.1 0.9 0.2 0.3 0.8 1.9 0.8 0.6
Smoking status: Current 1.3 2.0 8.3 1.6 1.3 1.4 0.9 1.0 1.7 1.3 1.9 -0.3 0.8 1.5 1.0 2.0 1.3 1.8 2.9 0.8 1.1 2.4 2.6 1.1 0.6 -0.8 -0.2 0.6 1.2 -0.1 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.7 0.0 -1.0 -0.6 -0.7 -0.8 -0.8 -1.2 -0.8 -0.6 -0.4 -0.3 -0.3 -0.5 -0.1 -0.7 -1.0 -0.4 -0.2 -0.2 -1.3 -0.2 -1.3 -0.1 -0.8 -1.3 -0.2 -0.5 -0.7
Whole body water mass 0.2 1.1 3.9 -0.2 1.5 1.4 1.4 1.6 1.6 2.0 0.0 0.2 1.1 1.0 -0.3 0.6 1.2 1.4 1.6 1.2 0.4 0.3 1.4 1.2 0.9 -0.7 -0.1 1.1 0.3 -0.2 0.1
Leg predicted mass (right) 0.2 0.9 3.2 -0.6 1.3 1.2 1.3 1.2 1.4 1.8 0.4 -0.1 1.2 0.9 0.1 0.1 1.2 1.4 1.4 1.2 0.1 0.1 1.1 1.3 0.5 -0.9 -0.3 0.7 -0.1 -0.5 -0.1
Arm fat mass (left) 0.7 3.0 7.2 1.2 1.5 2.7 1.8 1.6 2.7 2.4 1.9 -0.9 2.1 2.4 0.4 -0.1 2.6 2.3 2.2 2.0 -0.1 1.1 2.2 2.5 0.2 -2.1 -1.1 0.4 -0.2 -1.2 -0.8
Number of self-reported non-cancer illnesses 0.9 1.6 4.8 2.2 1.6 2.2 1.7 1.4 1.6 1.9 0.2 -0.2 1.2 1.9 0.1 -0.2 1.5 0.8 0.9 1.5 0.1 0.5 2.0 1.6 0.9 -1.1 -0.1 1.3 0.3 -0.4 -0.6
Average weekly champagne plus white wine intake 0.1 0.2 1.3 1.1 0.1 0.0 0.3 -0.2 0.1 0.4 0.4 -0.0 -0.3 -0.3 0.5 1.1 -0.1 -0.1 0.1 -0.1 -0.3 0.5 -0.0 -0.1 0.1 0.5 0.2 -0.4 -0.2 0.1 0.0
Miserableness 0.7 1.2 2.4 1.3 -0.4 -1.3 -1.4 0.8 -0.5 -1.2 -1.2 1.4 -1.4 -1.3 -1.0 0.9 -1.1 -1.1 -0.1 -1.4 1.4 -1.0 -0.3 -0.9 0.9 0.6 0.8 0.9 1.4 1.3 1.6
Guilty feelings 0.7 1.0 4.5 0.2 1.0 0.2 1.0 -0.2 -2.1 0.2 -1.0 0.5 -1.1 -0.7 -0.9 -0.2 -1.5 -0.4 -2.1 0.2 -1.2 -0.8 -1.5 -1.2 0.4 0.8 0.7 -0.1 -1.6 0.2 0.4
Wears glasses or contact lenses 1.3 1.5 4.2 0.2 0.0 1.3 1.0 1.4 1.6 1.1 -0.1 -1.0 1.9 1.8 0.2 0.1 2.0 1.1 1.8 1.6 -0.0 0.9 1.3 2.0 -0.8 -1.7 -1.4 -0.1 -0.0 -1.5 -1.2
Ever taken oral contraceptive pill 0.2 0.3 1.0 -0.2 0.1 0.4 0.8 -0.6 -0.4 0.4 0.1 -0.7 0.3 0.3 -0.9 0.3 0.1 0.4 -0.2 0.6 -1.0 -0.6 -0.2 0.1 -0.5 -0.3 -0.4 -0.7 -1.0 -0.6 -0.4
Hearing aid user 0.4 0.5 2.6 -0.5 0.1 -0.4 -0.4 -0.2 -1.2 -0.5 -0.6 0.4 -0.6 -0.5 0.1 -1.3 -1.1 -1.6 -0.5 -0.2 -0.7 -1.1 -1.2 -0.6 0.1 0.6 0.5 0.2 -0.7 0.2 0.5
Mother’s age at death 0.4 0.5 1.6 0.5 -0.1 0.5 0.5 1.1 0.6 0.8 -0.5 0.6 0.1 0.3 -0.7 0.5 0.3 0.5 0.6 0.3 1.2 0.0 1.0 0.6 1.2 -0.1 0.6 1.3 1.1 0.4 0.7
Financial situation satisfaction 2.8 3.5 8.5 -1.9 -0.6 1.8 1.5 -0.0 1.3 1.0 0.9 -2.5 2.9 2.5 1.5 0.2 2.4 1.4 1.6 2.3 -1.6 0.5 0.5 2.5 -2.0 -2.7 -2.6 -1.7 -1.5 -2.7 -2.6
Tinnitus: Yes, now most or all of the time 0.2 0.2 3.4 -0.7 -0.1 -0.2 0.2 0.1 -0.2 0.2 -0.3 -0.1 0.3 -0.0 -0.3 -0.7 -0.1 -0.8 0.1 0.2 -0.6 -1.9 -0.4 0.2 0.1 -0.0 0.1 0.5 -0.5 -0.1 0.0
Commuting to job workplace: Public transport 1.0 1.2 5.8 -1.2 0.8 0.6 0.8 -0.5 0.1 0.5 2.4 -1.3 1.2 0.9 2.1 -1.1 0.9 1.0 0.1 1.1 -1.2 1.2 -0.1 0.8 -0.8 -1.3 -1.1 -0.8 -1.1 -1.2 -1.2
Eye problems/disorders: Glaucoma 1.9 2.3 7.2 2.7 1.2 0.7 0.2 2.1 1.2 0.8 -1.0 1.9 -1.1 -0.1 -1.1 1.8 -0.0 -0.4 0.3 -0.4 2.2 -1.1 2.0 -0.0 2.2 1.3 2.0 2.5 2.3 1.7 1.9
Medication: Blood pressure 0.2 0.4 3.8 0.2 0.2 -0.2 0.0 1.1 0.3 0.3 -0.8 0.4 -0.1 -0.3 -1.4 -0.7 0.2 -0.8 -1.5 -0.0 0.0 -1.9 0.1 0.1 0.3 0.1 0.1 0.3 0.0 0.2 0.4
Pain type(s) experienced in last month: Hip pain 0.2 0.2 1.1 1.0 0.6 -0.1 0.1 -0.4 -0.6 0.0 0.3 0.1 -0.4 -0.2 -0.1 -0.4 -0.5 -0.3 -0.8 -0.1 -0.4 -1.0 -0.3 -0.4 0.5 -0.1 0.3 0.5 -0.4 0.4 0.1
Supplements: Fish oil (including cod liver oil) 2.3 3.1 9.8 0.6 2.1 3.1 2.6 2.0 2.1 3.1 0.7 -0.2 1.7 2.5 -0.2 0.9 1.7 0.9 2.0 2.3 0.2 -0.5 3.1 2.2 1.4 -1.0 0.3 2.1 0.3 -0.4 -0.4
High cholesterol (Self-reported) 0.4 0.8 2.3 0.7 0.9 1.3 1.1 0.6 0.8 1.3 1.4 -0.4 1.0 1.2 0.0 -1.5 0.9 0.8 0.6 1.1 -0.6 0.4 1.0 1.2 0.4 -0.8 -0.2 0.6 -0.5 -0.4 -0.5
Medication: Bendroflumethiazide 0.3 0.4 2.6 0.5 0.8 -0.2 -0.2 1.6 0.8 0.4 -0.1 0.9 -0.2 -0.4 -0.8 -0.0 0.2 0.3 -0.0 -0.2 0.7 -0.8 0.6 -0.1 0.9 0.4 0.5 0.9 0.8 0.7 0.9
Medication: Paracetamol 0.6 1.0 3.8 2.0 1.3 0.5 0.2 0.8 -0.2 -0.0 -0.7 1.0 -1.0 -0.3 -1.1 -0.7 -0.7 -1.5 1.2 -0.4 0.6 -1.4 1.0 -0.2 1.2 0.8 1.4 1.5 0.6 1.0 1.2
Medication: Lisinopril 0.2 0.2 1.1 -0.3 0.4 0.2 0.3 -0.4 0.3 0.4 1.0 -0.4 0.4 0.2 0.4 -1.1 0.5 0.8 0.3 0.3 -0.6 0.4 0.4 0.2 -0.2 -0.4 -0.3 -0.1 -0.6 -0.3 -0.5
Medication: Atorvastatin 1.4 1.7 4.0 -1.2 -0.7 0.5 0.7 -0.7 -0.1 0.0 0.6 -1.8 1.5 1.0 0.8 -1.9 1.1 0.3 -1.0 1.2 -1.9 0.4 -1.0 1.1 -1.8 -1.8 -1.9 -1.7 -2.0 -2.0 -1.7
Illnesses of father: High blood pressure 0.7 0.9 2.8 0.7 0.0 1.0 1.1 1.6 1.4 1.1 -0.3 -0.4 0.9 1.2 -0.6 0.4 1.5 0.4 1.7 1.1 0.3 -0.6 1.5 1.6 -0.1 -0.7 -0.4 -0.1 0.4 -0.7 -0.8
Alcohol drinker status: Never 0.8 1.0 2.6 0.2 0.8 1.5 1.5 -0.1 0.9 1.0 0.9 -1.0 1.1 1.5 1.1 0.8 1.3 0.6 0.7 1.5 -0.3 0.2 0.9 1.6 -0.7 -0.6 -0.5 -0.2 -0.4 -1.1 -1.1
Ever smoked 1.3 2.2 8.1 0.4 0.3 1.7 0.9 1.7 2.8 1.7 1.9 -0.6 1.9 1.9 0.4 -0.1 2.3 1.2 1.8 1.2 0.8 2.3 2.3 2.0 0.1 -1.6 -1.0 0.5 0.9 -0.8 -0.7
Basal metabolic rate 0.3 1.5 4.5 0.2 1.6 1.7 1.5 1.7 1.9 2.1 0.5 0.1 1.3 1.2 -0.2 0.6 1.5 1.8 1.9 1.3 0.4 0.6 1.7 1.5 0.9 -0.9 -0.2 1.1 0.3 -0.3 0.1
Leg fat percentage (left) 0.6 2.2 7.5 1.9 0.6 2.2 1.0 2.1 2.7 2.0 1.9 -0.1 1.3 1.9 -0.6 0.3 2.1 1.7 2.0 1.1 0.6 1.2 2.3 1.8 0.8 -1.2 -0.4 0.8 0.7 -0.3 -0.0
Arm fat-free mass (left) 0.2 1.1 3.5 0.1 1.6 1.4 1.2 1.7 1.6 1.9 0.5 0.4 1.0 0.9 -0.3 0.4 1.1 1.7 1.4 1.0 0.5 0.6 1.4 1.1 1.1 -0.6 0.1 1.2 0.4 -0.0 0.4
Number of operations (self-reported) 0.4 0.5 3.2 1.8 0.9 1.0 0.6 0.7 0.4 0.9 0.7 0.6 -0.4 0.4 -0.2 0.3 -0.1 -1.0 0.3 0.1 0.2 1.0 1.0 -0.0 0.9 0.6 0.8 1.0 0.4 0.7 0.6
Average weekly beer plus cider intake 0.2 0.3 1.4 -0.1 -0.7 -1.1 -1.2 0.2 0.0 -1.0 -0.5 0.4 -0.4 -1.0 0.1 0.3 -0.2 -0.1 -0.0 -1.1 0.7 0.1 -0.7 -0.4 -0.5 0.4 -0.0 -0.3 0.5 0.2 0.4
Irritability 0.4 0.7 2.3 -0.2 -0.5 -0.6 -0.6 -1.3 -0.8 -1.2 0.5 -1.1 0.5 0.2 0.8 -1.2 0.2 0.4 -1.4 0.2 -0.5 0.6 -1.5 0.3 -0.8 -1.5 -1.2 -0.8 -0.4 -0.9 -0.9
Risk taking 1.6 2.4 10.4 1.0 3.2 2.3 2.7 1.2 -0.2 2.8 0.4 1.4 -0.5 0.9 -0.3 1.7 -1.0 0.7 0.1 1.4 -0.3 -0.4 1.4 -0.5 2.2 2.0 2.2 1.7 -0.6 1.2 1.5
Ever had prostate specific antigen (PSA) test 0.7 0.8 2.9 -0.1 -0.1 -1.2 -1.1 -0.3 -0.7 -0.7 -0.1 0.8 -1.1 -1.2 -0.8 -1.5 -0.9 -1.0 -1.7 -1.2 0.4 -1.6 -0.8 -1.2 0.2 1.0 0.5 -0.0 0.2 0.8 0.5
Fractured/broken bones in last 5 years 1.5 1.9 6.9 2.1 1.2 0.4 0.3 1.7 1.2 1.1 -0.5 1.7 -0.6 -0.0 -1.0 1.7 -0.1 -0.3 0.6 -0.2 2.1 -1.3 1.9 0.0 2.2 1.0 1.8 2.6 1.9 1.6 1.4
Age started oral contraceptive pill 1.1 1.4 4.5 1.2 1.0 -0.5 -0.2 -0.3 -2.1 -0.7 -0.3 1.3 -1.6 -1.2 -0.4 -0.4 -2.1 -0.8 -1.7 -0.7 0.0 -1.1 -1.2 -1.4 1.3 1.7 1.8 1.3 -0.1 1.2 1.3
Diastolic blood pressure, automated reading 0.4 1.3 4.4 0.5 1.2 1.4 1.4 1.5 2.1 1.8 1.3 -0.5 1.5 1.1 -0.1 0.1 1.7 1.6 0.7 1.1 -0.1 0.4 1.5 1.6 0.2 -0.9 -0.5 0.1 -0.0 -0.6 -0.4
Ever depressed for a whole week 1.3 1.6 5.1 0.2 1.3 0.0 0.1 1.8 0.5 0.9 -1.4 2.0 -1.0 -0.7 -1.5 1.2 -0.7 -0.3 -0.6 -0.4 1.2 -0.8 0.8 -0.8 2.2 1.5 1.9 2.1 1.2 1.8 1.9
Unable to work because of sickness or disability 0.3 0.4 1.3 1.0 1.0 1.1 0.9 0.1 0.1 0.9 0.7 -0.1 0.4 0.8 0.3 0.6 -0.0 1.1 0.7 0.7 -0.4 -0.1 0.6 0.1 0.7 -0.3 0.2 0.6 -0.5 -0.0 0.1
Commuting to job workplace: Cycle 0.9 1.1 3.1 0.6 -0.3 -1.2 -1.4 0.3 -0.3 -1.0 -1.3 1.3 -1.1 -1.5 -0.4 0.2 -1.0 -1.1 -0.5 -1.8 1.2 -0.3 -0.4 -1.2 0.9 1.0 1.1 1.0 1.3 1.3 1.6
Myopia 1.7 2.5 7.3 -0.9 -1.7 0.6 0.3 -0.7 0.7 -0.2 1.6 -2.3 2.1 1.6 1.3 -1.2 1.9 0.9 0.6 1.2 -1.3 1.5 -0.2 1.8 -2.1 -2.5 -2.7 -2.1 -1.0 -2.3 -2.1
Vascular/heart problems diagnosed by doctor 0.4 1.2 5.3 -2.3 -1.6 -0.6 -0.5 -2.1 -1.6 -1.1 0.1 -0.7 -0.0 -0.2 0.6 0.2 -0.9 -0.7 -0.9 -0.3 -1.0 1.2 -2.1 -0.9 -1.3 0.1 -0.5 -1.2 -1.1 -0.6 -0.5
Cholesterol lowering medication 1.4 2.1 5.1 0.8 0.3 1.8 1.8 0.9 1.7 2.0 1.3 -1.3 2.3 2.0 0.3 0.2 2.0 1.6 1.5 1.9 -0.5 1.6 1.7 2.0 0.0 -2.1 -1.1 0.5 -0.5 -1.3 -1.1
Medication: Omeprazole (e.g. Zanprol) 0.3 0.3 2.0 1.2 0.3 0.4 0.3 -0.1 -0.7 -0.0 -0.8 0.2 -0.5 -0.2 -1.4 -0.3 -0.7 -0.9 -0.3 -0.2 -0.4 -1.2 -0.3 -0.6 0.3 0.5 0.4 0.1 -0.6 0.4 0.1
Pain experienced in last month 1.1 1.9 5.2 -2.3 -0.2 0.0 0.5 -0.8 -0.0 -0.1 1.8 -1.7 1.4 0.6 2.0 -1.9 1.1 1.0 -0.7 1.0 -1.5 1.3 -1.1 1.1 -1.7 -1.6 -1.7 -1.8 -1.7 -1.9 -1.6
Supplements: Calcium 2.4 2.6 5.2 1.4 -0.3 -1.5 -1.5 1.1 -0.6 -1.2 -2.3 2.3 -2.0 -1.7 -2.0 0.8 -1.6 -1.5 0.1 -1.8 2.1 -0.8 0.2 -1.5 1.6 2.1 1.9 1.6 2.3 2.2 2.0
Basal cell carcinoma (self-reported) 1.1 1.3 4.4 0.7 2.1 1.1 1.4 0.8 0.1 1.7 0.6 1.3 -0.3 0.2 -0.7 1.0 -0.7 -0.2 -0.2 0.5 0.4 -1.2 1.1 -0.2 2.0 1.4 1.9 2.0 0.2 1.1 1.3
Heart attack/myocardial infarction (self-reported) 0.6 0.8 4.3 -0.8 0.6 0.5 0.9 -1.5 -0.8 0.5 1.1 -1.1 0.4 0.6 0.9 -0.7 -0.2 0.2 -0.2 1.1 -2.0 0.3 -0.5 -0.3 -0.6 -0.4 -0.5 -0.9 -2.1 -0.7 -0.9
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 3.8 0.9 1.9 1.3 1.5 -0.2 -0.4 0.7 1.1 -0.7 0.4 0.7 1.4 0.2 0.1 0.2 0.5 1.1 -1.5 0.8 -0.0 0.2 -0.2 -0.6 -0.3 -0.1 -1.7 -0.7 -0.3
Heart disease (siblings) 0.8 1.0 5.5 1.1 2.3 1.5 1.6 1.4 0.8 1.4 1.0 0.5 0.5 0.8 0.5 -0.1 0.3 1.0 0.5 1.2 0.2 0.2 1.4 0.8 1.1 0.1 0.7 1.5 0.1 0.2 0.6
Alcohol drinker status: Previous 0.9 1.1 3.0 0.2 1.2 -0.2 -0.4 0.9 -0.5 0.1 -0.4 1.7 -1.1 -0.7 -0.0 -0.0 -1.4 -0.6 -0.3 -0.6 0.8 0.4 -0.1 -1.0 1.7 1.6 1.7 1.7 0.7 1.6 1.7
Pack years of smoking 0.3 0.4 3.2 0.9 0.8 0.7 0.5 0.6 0.3 0.6 0.8 -0.1 0.5 0.6 0.3 1.1 0.2 1.8 0.7 0.6 -0.3 -0.3 0.6 0.3 0.5 -0.3 0.2 0.4 -0.5 -0.1 -0.0
Impedance of whole body 0.4 2.0 5.1 -0.3 -1.4 -2.2 -1.9 -1.7 -1.8 -2.2 -0.7 0.6 -1.9 -2.0 -0.3 -0.5 -2.0 -1.5 -1.4 -1.9 -0.0 -0.1 -1.4 -2.1 -0.3 1.7 0.9 -0.5 0.1 1.1 0.8
Leg fat mass (left) 0.6 2.4 6.8 1.1 1.1 2.5 1.5 1.7 2.6 2.4 1.8 -0.5 1.7 2.1 -0.2 0.2 2.2 2.1 2.2 1.6 0.1 0.9 2.2 2.0 0.6 -1.6 -0.7 0.6 0.1 -0.7 -0.4
Arm predicted mass (left) 0.3 1.6 4.9 0.3 1.6 1.7 1.4 1.9 2.0 2.2 0.4 0.3 1.3 1.2 -0.3 0.9 1.4 2.0 1.7 1.2 0.7 0.7 1.8 1.4 1.2 -0.7 0.1 1.3 0.6 -0.1 0.3