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chr9:97,940,807-101,710,041

Best TWAS P=8.13e-58 · Best GWAS P=3.02e-77 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CTSL2	0.04	0.03	lasso	9	0.03	5.0e-05	-4.99	6.2	5.4e-10	0.22	0.77	0.01	FALSE
2	CommonMind	Brain Pre-frontal Cortex	LOC441454	0.05	0.01	lasso	3	0.02	1.5e-03	-7.90	-10.9	1.3e-27	-0.39	0.09	0.05	TRUE
3	CommonMind	Brain Pre-frontal Cortex	NANS	0.08	0.09	lasso	3	0.08	2.4e-10	5.62	5.6	2.5e-08	-0.07	1.00	0.00	TRUE
4	GTEx	Adipose Subcutaneous	HSD17B3	0.21	0.01	enet	31	0.04	1.9e-04	-11.53	-5.5	5.0e-08	-0.15	0.39	0.02	FALSE
5	GTEx	Adipose Subcutaneous	TMOD1	0.05	0.00	lasso	2	0.00	1.8e-01	-5.12	-5.5	3.0e-08	-0.12	0.16	0.03	FALSE
6	GTEx	Adipose Subcutaneous	C9orf156	0.26	0.17	lasso	4	0.25	3.9e-20	-7.58	-13.6	4.3e-42	-0.07	0.01	0.99	FALSE
7	GTEx	Adipose Visceral Omentum	C9orf156	0.19	0.15	lasso	4	0.11	1.6e-06	-7.58	-7.7	2.0e-14	-0.06	0.82	0.10	FALSE
8	GTEx	Artery Coronary	TMOD1	0.18	0.01	enet	11	0.11	1.8e-04	1.77	5.1	2.8e-07	0.26	0.07	0.18	FALSE
9	GTEx	Artery Tibial	C9orf156	0.16	0.12	lasso	6	0.16	1.2e-12	17.33	-14.8	8.1e-50	-0.06	0.01	0.99	FALSE
10	GTEx	Artery Tibial	CCDC180	0.09	0.04	lasso	9	0.03	1.0e-03	-5.18	5.9	3.0e-09	0.13	0.84	0.01	FALSE
11	GTEx	Artery Tibial	RP11-23J9.4	0.10	0.03	lasso	6	0.05	6.2e-05	-5.12	5.8	5.0e-09	0.15	0.96	0.00	FALSE
12	GTEx	Brain Caudate basal ganglia	C9orf156	0.40	0.40	lasso	4	0.39	3.1e-12	-6.86	-7.7	2.0e-14	-0.04	0.92	0.07	FALSE
13	GTEx	Brain Cerebellar Hemisphere	C9orf156	0.26	0.22	lasso	2	0.14	1.9e-04	-7.58	-7.6	3.5e-14	-0.07	0.16	0.42	FALSE
14	GTEx	Brain Cerebellum	C9orf156	0.30	0.27	lasso	7	0.24	8.1e-08	-6.84	-7.5	7.5e-14	-0.05	0.22	0.76	FALSE
15	GTEx	Brain Cortex	C9orf156	0.51	0.32	enet	11	0.29	8.1e-09	-7.58	-6.3	2.2e-10	-0.07	0.89	0.05	FALSE
16	GTEx	Brain Frontal Cortex BA9	C9orf156	0.15	0.28	lasso	1	0.26	1.1e-07	-7.58	-7.6	3.6e-14	-0.07	0.39	0.28	FALSE
17	GTEx	Brain Hypothalamus	TBC1D2	0.27	0.00	enet	39	0.00	2.5e-01	-3.14	5.3	1.3e-07	0.00	0.12	0.10	FALSE
18	GTEx	Brain Nucleus accumbens basal ganglia	C9orf156	0.26	0.32	lasso	3	0.30	7.9e-09	-6.86	-7.6	3.6e-14	-0.04	0.22	0.72	FALSE
19	GTEx	Brain Putamen basal ganglia	C9orf156	0.27	0.24	lasso	1	0.24	2.6e-06	-6.86	-6.9	7.1e-12	-0.05	0.15	0.40	FALSE
20	GTEx	Breast Mammary Tissue	CDC14B	0.16	0.02	enet	21	0.02	3.7e-02	-11.69	12.5	1.1e-35	0.35	0.36	0.25	FALSE
21	GTEx	Breast Mammary Tissue	C9orf156	0.30	0.20	enet	16	0.21	3.3e-11	-6.86	-8.3	9.1e-17	-0.06	0.96	0.04	TRUE
22	GTEx	Breast Mammary Tissue (Male)	C9orf156	0.13	-0.01	enet	1	-0.01	5.6e-01	-7.58	-7.6	3.6e-14	-0.07	0.03	0.40	FALSE
23	GTEx	Breast Mammary Tissue (Female)	C9orf156	0.42	0.22	lasso	10	0.23	1.5e-07	-7.58	-6.6	4.2e-11	-0.09	0.36	0.29	TRUE
24	GTEx	Cells EBV-transformed lymphocytes	C9orf156	0.29	0.23	lasso	3	0.19	1.1e-06	-6.84	-6.8	1.3e-11	-0.05	0.69	0.11	FALSE
25	GTEx	Cells EBV-transformed lymphocytes	AAED1	0.17	0.02	lasso	3	0.04	2.4e-02	-11.18	-10.1	7.2e-24	-0.25	0.09	0.05	FALSE
26	GTEx	Cells Transformed fibroblasts	NANS	0.41	0.26	enet	20	0.28	2.6e-21	10.42	9.9	5.0e-23	0.06	1.00	0.00	FALSE
27	GTEx	Cells Transformed fibroblasts	RP11-23J9.4	0.10	0.08	lasso	6	0.08	6.4e-07	-4.99	5.3	9.1e-08	0.16	0.96	0.00	FALSE
28	GTEx	Colon Sigmoid	C9orf156	0.19	0.17	lasso	5	0.15	7.4e-06	-6.84	-9.8	1.5e-22	-0.06	0.03	0.94	FALSE
29	GTEx	Colon Sigmoid	RP11-23J9.4	0.11	0.02	lasso	8	0.01	1.3e-01	-5.12	5.5	3.7e-08	0.15	0.19	0.04	FALSE
30	GTEx	Colon Transverse	C9orf156	0.21	0.22	lasso	4	0.20	4.5e-10	-6.84	-7.7	1.8e-14	-0.06	0.70	0.29	FALSE
31	GTEx	Esophagus Gastroesophageal Junction	C9orf156	0.20	0.14	lasso	3	0.22	1.9e-08	-7.58	-11.1	1.2e-28	-0.08	0.07	0.92	FALSE
32	GTEx	Esophagus Gastroesophageal Junction	CCDC180	0.16	0.01	enet	18	0.02	7.6e-02	-5.28	6.3	3.9e-10	0.19	0.26	0.04	FALSE
33	GTEx	Esophagus Gastroesophageal Junction	RP11-23J9.4	0.18	0.01	lasso	15	0.01	2.0e-01	-5.37	5.3	1.2e-07	0.17	0.22	0.05	FALSE
34	GTEx	Esophagus Mucosa	TMOD1	0.12	0.04	enet	21	0.05	3.7e-04	-3.81	-5.9	3.6e-09	-0.18	0.21	0.04	FALSE
35	GTEx	Esophagus Mucosa	C9orf156	0.19	0.13	lasso	4	0.14	2.6e-09	-7.58	-10.8	3.6e-27	-0.08	0.21	0.78	FALSE
36	GTEx	Esophagus Muscularis	C9orf156	0.32	0.28	lasso	4	0.35	2.5e-22	17.33	-14.8	1.4e-49	-0.06	0.01	0.99	FALSE
37	GTEx	Esophagus Muscularis	RP11-535M15.2	0.19	0.04	enet	11	0.05	3.6e-04	-0.58	7.8	4.3e-15	0.50	0.09	0.75	TRUE
38	GTEx	Heart Left Ventricle	C9orf156	0.23	0.18	enet	13	0.16	9.3e-09	-7.58	-7.6	2.4e-14	-0.08	0.78	0.22	FALSE
39	GTEx	Muscle Skeletal	C9orf156	0.35	0.23	lasso	9	0.25	7.5e-25	-6.86	-11.3	7.7e-30	-0.05	0.94	0.06	TRUE
40	GTEx	Muscle Skeletal	CCDC180	0.05	0.01	lasso	3	0.02	4.8e-03	-4.69	5.5	4.3e-08	0.18	0.87	0.01	FALSE
41	GTEx	Muscle Skeletal	RP11-23J9.4	0.06	0.01	enet	23	0.03	1.1e-03	-4.69	6.3	2.8e-10	0.21	0.90	0.01	TRUE
42	GTEx	Nerve Tibial	HSD17B3	0.14	0.00	enet	20	0.00	2.4e-01	-10.81	-9.6	1.3e-21	-0.21	0.13	0.04	FALSE
43	GTEx	Nerve Tibial	C9orf156	0.20	0.17	lasso	4	0.15	7.9e-11	-7.58	-11.4	6.9e-30	-0.07	0.18	0.82	FALSE
44	GTEx	Nerve Tibial	ZNF367	0.10	0.05	lasso	3	0.02	7.9e-03	-10.46	-10.7	7.5e-27	-0.27	0.65	0.02	FALSE
45	GTEx	Nerve Tibial	RP11-23J9.4	0.42	0.08	lasso	8	0.07	1.0e-05	-5.37	5.3	9.1e-08	0.03	0.82	0.01	FALSE
46	GTEx	Ovary	C9orf156	0.39	0.23	enet	15	0.18	3.9e-05	-7.58	-6.1	8.4e-10	-0.08	0.08	0.74	FALSE
47	GTEx	Pituitary	CCDC180	0.19	0.07	lasso	5	0.06	1.3e-02	-4.99	6.5	1.1e-10	0.16	0.12	0.12	FALSE
48	GTEx	Pituitary	RP11-23J9.4	0.21	0.05	lasso	4	0.07	9.2e-03	-4.82	6.4	1.7e-10	0.16	0.15	0.15	TRUE
49	GTEx	Skin Not Sun Exposed Suprapubic	C9orf156	0.16	0.11	lasso	2	0.10	5.1e-06	-7.58	-10.4	1.6e-25	-0.07	0.04	0.95	FALSE
50	GTEx	Skin Not Sun Exposed Suprapubic	CCDC180	0.16	0.11	lasso	11	0.11	2.0e-06	-4.98	5.4	8.4e-08	0.13	0.97	0.00	FALSE
51	GTEx	Skin Not Sun Exposed Suprapubic	RP11-23J9.4	0.14	0.11	lasso	12	0.09	1.3e-05	-5.28	5.4	6.6e-08	0.12	0.90	0.01	FALSE
52	GTEx	Skin Sun Exposed Lower leg	C9orf156	0.22	0.12	enet	16	0.18	1.3e-14	-7.58	-10.0	2.2e-23	-0.07	0.95	0.05	FALSE
53	GTEx	Stomach	C9orf156	0.18	0.19	lasso	1	0.18	5.9e-09	-7.58	-7.6	3.6e-14	-0.07	0.92	0.06	FALSE
54	GTEx	Testis	HABP4	0.19	0.22	lasso	9	0.21	1.1e-09	-11.92	-11.8	3.3e-32	-0.28	1.00	0.00	FALSE
55	GTEx	Testis	C9orf156	0.39	0.40	enet	14	0.41	1.1e-19	-7.58	-7.4	1.2e-13	-0.04	1.00	0.00	FALSE
56	GTEx	Thyroid	CDC14B	0.15	0.10	lasso	5	0.08	5.3e-07	-11.59	11.2	2.3e-29	0.27	0.97	0.01	FALSE
57	GTEx	Thyroid	C9orf156	0.21	0.26	lasso	1	0.26	7.9e-20	-7.58	-7.6	3.6e-14	-0.07	1.00	0.00	FALSE
58	GTEx	Thyroid	CCDC180	0.17	0.20	lasso	8	0.22	1.1e-16	-4.69	5.5	3.2e-08	0.17	1.00	0.00	FALSE
59	GTEx	Thyroid	RP11-23J9.4	0.17	0.21	lasso	9	0.23	2.4e-17	-4.69	5.5	4.0e-08	0.17	1.00	0.00	FALSE
60	GTEx	Whole Blood	CCDC180	0.06	0.00	lasso	5	0.00	4.1e-01	-4.95	9.1	7.7e-20	0.30	0.02	0.72	FALSE
61	GTEx	Whole Blood	RP11-23J9.4	0.08	0.00	lasso	4	0.00	3.4e-01	-4.95	9.1	9.7e-20	0.33	0.02	0.77	FALSE
62	METSIM	Adipose	C9orf156	0.15	0.17	lasso	5	0.17	4.3e-25	-7.58	-7.4	1.5e-13	-0.07	1.00	0.00	TRUE
63	METSIM	Adipose	ERCC6L2	0.06	0.01	bslmm	569	0.03	4.6e-05	-0.44	7.1	1.4e-12	0.17	0.15	0.17	FALSE
64	METSIM	Adipose	HSD17B3	0.06	0.00	bslmm	427	0.01	2.4e-03	-11.53	-7.1	1.1e-12	-0.24	0.06	0.12	FALSE
65	YFS	Blood	CORO2A	0.03	0.01	bslmm	606	0.01	1.4e-04	0.91	-7.8	4.7e-15	-0.02	0.08	0.43	TRUE
66	YFS	Blood	HABP4	0.08	0.09	enet	24	0.11	5.9e-34	-11.22	15.6	9.9e-55	0.48	1.00	0.00	TRUE
67	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C9orf156	0.15	0.02	enet	12	0.06	1.4e-05	-7.70	-6.6	3.7e-11	-0.10	0.17	0.12	FALSE
68	The Cancer Genome Atlas	Breast Invasive Carcinoma	C9orf156	0.06	0.06	lasso	5	0.07	4.3e-14	-7.58	-11.8	2.8e-32	-0.09	0.76	0.24	FALSE
69	The Cancer Genome Atlas	Breast Invasive Carcinoma	CDC14B	0.02	0.01	lasso	1	0.01	3.0e-03	-11.84	11.8	2.6e-32	0.29	0.06	0.02	FALSE
70	The Cancer Genome Atlas	Breast Invasive Carcinoma	HSD17B3	0.02	0.01	enet	7	0.01	7.3e-03	3.31	-6.0	2.3e-09	-0.22	0.16	0.40	FALSE
71	The Cancer Genome Atlas	Glioblastoma Multiforme	C9orf156	0.24	0.19	blup	46	0.20	1.4e-06	-6.84	-12.6	2.0e-36	-0.07	0.08	0.80	FALSE
72	The Cancer Genome Atlas	Glioblastoma Multiforme	CDC14B	0.16	0.17	blup	41	0.19	2.6e-06	-11.18	9.9	4.5e-23	0.20	0.58	0.02	FALSE
73	The Cancer Genome Atlas	Glioblastoma Multiforme	HABP4	0.08	0.06	blup	44	0.05	1.6e-02	-11.59	12.2	4.2e-34	0.30	0.06	0.05	FALSE
74	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C9orf156	0.03	0.03	enet	2	0.03	1.1e-04	-6.86	-6.9	7.1e-12	-0.05	0.11	0.06	FALSE
75	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HABP4	0.02	0.02	blup	44	0.02	7.1e-03	-11.18	-9.9	2.6e-23	-0.18	0.09	0.03	FALSE
76	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C9orf156	0.11	0.08	blup	46	0.11	1.0e-12	-7.58	-13.6	2.5e-42	-0.06	0.04	0.96	FALSE
77	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CDC14B	0.03	0.02	blup	42	0.02	2.1e-03	-11.18	8.6	5.7e-18	0.11	0.10	0.03	FALSE
78	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TDRD7	0.03	0.03	lasso	3	0.02	8.5e-04	6.27	-5.5	4.7e-08	-0.15	0.30	0.10	FALSE
79	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C9orf156	0.24	0.08	enet	17	0.10	2.4e-06	12.52	-9.9	4.2e-23	-0.06	0.07	0.80	FALSE
80	The Cancer Genome Atlas	Brain Lower Grade Glioma	C9orf156	0.18	0.23	lasso	4	0.23	1.9e-25	-7.58	-7.0	3.0e-12	-0.07	1.00	0.00	FALSE
81	The Cancer Genome Atlas	Brain Lower Grade Glioma	CDC14B	0.05	0.06	lasso	5	0.06	6.5e-07	-11.34	12.5	9.9e-36	0.37	1.00	0.00	FALSE
82	The Cancer Genome Atlas	Brain Lower Grade Glioma	HABP4	0.05	0.08	lasso	5	0.08	6.9e-09	-11.53	11.6	3.8e-31	0.27	1.00	0.00	TRUE
83	The Cancer Genome Atlas	Brain Lower Grade Glioma	KIAA1529	0.02	0.00	blup	92	0.01	2.3e-02	-5.12	5.5	4.1e-08	0.16	0.02	0.67	FALSE
84	The Cancer Genome Atlas	Brain Lower Grade Glioma	LOC340508	0.06	0.01	lasso	2	0.01	1.9e-02	-5.73	5.8	6.3e-09	0.27	0.05	0.11	FALSE
85	The Cancer Genome Atlas	Lung Adenocarcinoma	C9orf156	0.04	0.01	blup	46	0.02	1.2e-03	17.37	-14.0	1.4e-44	-0.06	0.01	0.97	FALSE
86	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C9orf156	0.07	0.03	lasso	2	0.03	2.1e-04	-7.58	-7.4	1.5e-13	-0.06	0.33	0.18	FALSE
87	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C9orf156	0.09	0.07	blup	46	0.08	8.4e-06	-7.58	-13.5	2.8e-41	-0.06	0.16	0.72	FALSE
88	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FOXE1	0.13	0.08	lasso	3	0.08	7.0e-06	7.41	5.8	5.6e-09	-0.03	0.57	0.02	FALSE
89	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C9orf156	0.12	0.03	blup	46	0.09	9.0e-05	-7.58	-10.8	3.0e-27	-0.05	0.07	0.84	FALSE
90	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	HSD17B3	0.13	0.02	blup	97	0.04	9.1e-03	-11.53	-6.9	4.2e-12	-0.22	0.01	0.63	FALSE
91	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C9orf156	0.31	0.12	enet	7	0.11	3.4e-05	-7.70	-6.7	2.0e-11	-0.09	0.23	0.05	FALSE
92	The Cancer Genome Atlas	Prostate Adenocarcinoma	C9orf156	0.12	0.03	blup	46	0.05	2.4e-06	-6.86	-12.3	7.6e-35	-0.02	0.05	0.93	FALSE
93	The Cancer Genome Atlas	Prostate Adenocarcinoma	KIAA1529	0.05	0.02	lasso	10	0.05	6.5e-06	-4.99	5.5	3.0e-08	0.17	0.04	0.95	FALSE
94	The Cancer Genome Atlas	Soft Tissue Sarcoma	C9orf156	0.05	0.03	enet	8	0.03	9.8e-03	17.23	-16.0	8.1e-58	-0.05	0.02	0.66	TRUE
95	The Cancer Genome Atlas	Stomach Adenocarcinoma	CDC14B	0.08	0.02	blup	41	0.04	1.0e-03	-7.90	9.3	1.7e-20	0.14	0.06	0.03	FALSE
96	The Cancer Genome Atlas	Stomach Adenocarcinoma	KIAA1529	0.07	0.01	blup	92	0.02	8.1e-03	-4.99	6.2	4.6e-10	0.22	0.03	0.71	FALSE
97	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SLC35D2	0.18	0.04	blup	74	0.07	1.8e-03	-6.55	5.8	6.2e-09	0.09	0.03	0.19	FALSE
98	The Cancer Genome Atlas	Thyroid Carcinoma	C9orf156	0.29	0.15	lasso	5	0.13	1.0e-12	-7.58	-8.1	6.4e-16	-0.08	1.00	0.00	FALSE
99	The Cancer Genome Atlas	Thyroid Carcinoma	CDC14B	0.05	0.07	blup	42	0.08	4.8e-08	-11.59	8.8	1.8e-18	0.12	1.00	0.00	FALSE
100	The Cancer Genome Atlas	Thyroid Carcinoma	NANS	0.06	0.03	lasso	3	0.03	5.1e-04	10.41	10.5	5.9e-26	0.04	0.00	0.99	TRUE