TWAS hub - SCAMP3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.045	0.021	0.0014	0.045	0.023	0.029	0.028	0.035	3.4e-06	0.00068	0.00015	0.00022	3.8e-05
2	GTEx	Testis	0.087	0.042	0.0029	0.007	NA	0.013	NA	0.018	1.5e-01	NA	0.08200	NA	5.1e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Crohns Disease (2012)	18.1	29.2	32.6	-5.1	5.7
Irritable Bowel Disease (IBD)	12.2	29.0	31.0	-5.6	5.2
Crohns Disease (2017)	11.5	25.3	25.6	-5.1	5.0
Breast Cancer	10.7	25.9	27.1	5.2	-5.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	10.7	12.7	12.9	-3.5	3.6
Medication: Ramipril	8.1	10.4	14.7	-3.8	2.5
Qualifications: NVQ or HND or HNC or equivalent	7.2	8.7	9.3	-3.0	2.9
Medication for cholesterol, blood pressure or diabetes	6.0	9.9	10.3	3.2	-3.1
Ulcerative Colitis (UC)	5.7	10.7	13.4	-3.7	2.8
Financial situation satisfaction	5.6	6.9	7.7	-2.8	2.5
Pain experienced in last month	5.6	9.4	11.1	-3.3	2.8
Medication: Blood pressure	5.4	9.6	11.7	-2.7	3.4
Schizophrenia (2014)	5.1	11.1	15.6	-2.6	4.0
Number of full brothers	5.1	6.5	7.6	-2.8	2.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.8	5.6	6.2	2.5	-2.2
Bipolar Disorder or Schizophrenia	4.7	11.4	15.5	-2.7	3.9
Mouth/teeth dental problems: Dentures	4.6	7.7	11.2	-3.4	2.0
Ulcerative Colitis	4.4	6.4	7.1	-2.7	2.4
Tinnitus: Yes, but not now, but have in the past	4.3	4.6	5.1	2.2	-2.0
Hair/balding pattern: Pattern 2	4.3	5.5	7.3	-2.7	1.9
Medication: Atorvastatin	4.3	5.3	7.5	-2.7	1.8
Nervous feelings	4.0	7.4	12.1	3.5	-1.6
Qualifications: CSEs or equivalent	3.9	5.1	5.8	-2.1	2.4
Schizophrenia (2018)	3.7	7.6	11.8	-1.9	3.4
Number of full sisters	3.7	4.5	7.8	-2.8	1.1
Medication: Aspirin	3.7	4.9	5.9	-2.0	2.4
Severe depression (siblings)	3.6	4.0	4.0	-2.0	2.0
Current tobacco smoking	3.4	5.6	6.3	-2.5	2.2
Medication: Ibuprofen (e.g. Nurofen)	3.3	4.2	5.4	1.7	-2.3
Migraine (self-reported)	3.3	4.1	5.7	2.4	-1.6
Mean Putamen Volume	3.2	3.7	5.7	-2.4	1.3
High blood pressure (mother)	3.2	4.5	4.7	2.1	-2.2
Medication: Ibuprofen	3.0	3.6	5.2	1.4	-2.3
Worry (Nagel 2018)	2.9	6.0	9.6	3.1	-1.6
Medication: Aspirin	2.9	3.8	5.2	-1.6	2.3
Miserableness	2.9	5.1	6.5	-1.9	2.5
Basal cell carcinoma (self-reported)	2.9	3.4	3.6	1.9	-1.8
Smoking Status	2.7	6.5	8.0	-2.8	2.2
Maternal smoking around birth	2.7	3.8	4.2	-2.0	1.9
Loud music exposure frequency	2.7	2.9	4.2	2.0	-1.3
Qualifications: College or University degree	2.7	8.6	10.6	3.3	-2.6
Bipolar Disorder (2018)	2.6	4.0	4.1	-2.0	2.0
Townsend deprivation index at recruitment	2.6	3.7	4.0	-1.9	2.0
Mouth/teeth dental problems	2.6	4.0	5.7	2.4	-1.5
Diabetes (mother)	2.5	3.2	3.9	-1.6	2.0
Birth weight	2.5	5.5	8.0	2.8	-1.7
Risk taking	2.5	3.6	3.9	-2.0	1.8
Family relationship satisfaction	2.4	3.0	3.9	-1.4	2.0
Medication: Gliclazide	2.4	2.7	3.1	-1.5	1.8
Chest pain or discomfort	2.3	3.2	4.4	-2.1	1.5
Breastfed as a baby	2.2	2.7	3.2	-1.5	1.8
Time employed in main current job	2.1	2.5	2.8	1.4	-1.7
Medication: Cholesterol lowering	2.1	3.3	4.5	-2.1	1.4
Alzheimer’s Disease (in father)	2.0	2.2	3.2	1.1	-1.8
Illnesses of father: None of the above (group 1)	2.0	2.5	2.9	-1.5	1.7
Cardiovascular Disease	1.9	6.4	7.2	-2.7	2.3
Tanning	1.9	23.0	23.0	-4.8	4.8
Ever had hysterectomy (womb removed)	1.9	2.1	2.9	1.7	-1.2
Worrier / anxious feelings	1.9	3.6	5.2	2.3	-1.4
Smoking status: Current	1.9	3.0	3.5	-1.9	1.6
Fasting Glucose	1.8	2.1	3.6	-1.9	0.8
Diabetes (self-reported)	1.8	2.8	4.3	-2.1	1.1
Health satisfaction	1.8	2.3	2.8	1.7	-1.3
Diastolic blood pressure, automated reading	1.8	5.5	7.1	1.9	-2.7
Body Mass Index (BMI) (2010)	1.7	2.3	3.4	1.1	-1.9
Pulse rate, automated reading	1.7	5.5	6.6	2.6	-2.1
Breast cancer (self-reported)	1.7	2.0	2.2	-1.5	1.3
High cholesterol (Self-reported)	1.7	3.1	5.5	-2.3	0.9
Diabetes diagnosed by doctor	1.6	2.6	4.5	-2.1	0.9
Eye problems/disorders: Diabetes related eye disease	1.5	1.7	2.6	0.9	-1.6
Qualifications: A levels/AS levels or equivalent	1.5	3.4	4.0	2.0	-1.6
Shortness of breath walking on level ground	1.5	1.8	3.3	1.8	-0.5
Depressed Affect (Nagel 2018)	1.4	2.9	4.1	-1.3	2.0
Type 2 Diabetes (T2D) (2012)	1.4	1.6	1.6	-1.3	1.3
Sensitivity / hurt feelings	1.4	2.4	4.4	2.1	-0.6
Frequency of depressed mood in last 2 weeks	1.4	1.9	2.3	-1.2	1.5
Hair/balding pattern: Pattern 3	1.4	2.1	3.5	1.9	-0.9
Mouth/teeth dental problems: Bleeding gums	1.4	1.9	2.4	-1.5	1.2
Wheeze or whistling in the chest in last year	1.4	2.6	3.0	-1.5	1.7
Eye problems/disorders: Cataract	1.4	1.7	2.0	-1.4	1.2
Average weekly champagne plus white wine intake	1.4	1.9	2.0	1.3	-1.4
Lung FVC	1.3	6.5	8.2	2.9	-2.2
Ever used hormone-replacement therapy (HRT)	1.3	1.7	1.9	1.2	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	1.8	-1.4	1.3
Impedance of leg (left)	1.3	6.4	8.6	-2.0	2.9
Pain all over the body in last month	1.3	1.4	1.9	1.4	-1.0
Stomach or abdominal pain in last month	1.2	1.5	1.8	1.3	-1.1
Arm fat percentage (right)	1.2	4.6	5.2	2.3	-2.0
Impedance of arm (left)	1.2	5.7	11.2	3.4	-0.3
Hair/balding pattern: Pattern 4	1.2	2.9	3.3	1.8	-1.6
Blood clot in the leg (DVT)	1.2	1.5	1.6	-1.3	1.2
Age at first live birth	1.2	2.2	2.4	1.6	-1.4
Medication: Seretide 50 evohaler	1.2	1.4	1.5	-1.1	1.2
Ever taken oral contraceptive pill	1.2	1.3	1.3	-1.2	1.1
HDL Cholesterol	1.1	1.9	2.4	1.5	-1.2
Impedance of leg (right)	1.1	5.3	7.1	-1.8	2.7
Fed-up feelings	1.1	2.0	3.1	-0.9	1.8
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	1.6	1.3	-1.0
Heart attack	1.1	1.5	2.1	-1.5	0.9
Illnesses of siblings	1.1	1.6	2.2	1.0	-1.5
Impedance of arm (right)	1.1	4.9	9.6	3.1	-0.5
Chronic bronchitis/emphysema (mother)	1.1	1.2	1.5	-1.2	1.0
Comparative body size at age 10	1.1	2.9	4.2	1.3	-2.1
Hypertension (Self-reported)	1.1	3.0	3.2	-1.7	1.8
Smoking status: Previous	1.1	1.6	2.3	-1.5	0.9
Arm fat percentage (left)	1.1	4.6	5.5	2.4	-1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	2.7	1.6	-1.4
Tinnitus: Yes, now most or all of the time	1.1	1.3	1.6	1.2	-1.0
Fractured/broken bones in last 5 years	1.1	1.4	2.4	-1.6	0.7
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	1.6	-1.3	1.0
Heart disease (siblings)	1.1	1.4	1.8	-1.0	1.4
Depression (Nagel 2018)	1.0	1.5	2.0	-1.0	1.4
Waist Hip Ratio (WHR)	1.0	4.6	8.3	-0.9	2.9
Relative age of first facial hair	1.0	2.1	2.3	-1.5	1.4
Relative age voice broke	1.0	1.6	3.0	-1.7	0.2
Hayfever, allergic rhinitis or eczema	1.0	2.2	2.6	-1.6	1.4
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	2.4	-1.6	0.9
Pulse wave reflection index	1.0	1.2	1.5	-1.2	1.0
Glaucoma (self-reported)	1.0	1.1	1.9	0.6	-1.4
Loneliness, isolation	1.0	1.4	2.1	-0.9	1.4
Asthma (self-reported)	1.0	2.0	2.5	-1.6	1.2
Guilty feelings	1.0	1.5	1.5	-1.2	1.2
Ever smoked	1.0	1.7	2.1	-1.5	1.2
Vascular/heart problems diagnosed by doctor	1.0	2.8	2.9	1.7	-1.7
Supplements: Calcium	1.0	1.1	1.4	-0.9	1.2
HbA1C	0.9	1.0	2.0	-1.4	-0.1
Supplements: Zinc	0.9	1.0	1.4	0.8	-1.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	1.2	-1.1	1.1
Number of live births	0.9	1.3	2.2	-1.5	0.6
Lung cancer (father)	0.9	1.1	1.9	-0.5	1.4
Peak expiratory flow (PEF)	0.9	2.1	3.4	0.9	-1.9
Hearing aid user	0.9	1.0	1.2	1.1	-0.9
Eye problems/disorders: Glaucoma	0.9	1.0	1.2	0.9	-1.1
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.0	-1.4	0.6
Coronary Artery Disease (CAD)	0.8	1.0	1.2	0.9	-1.1
LDL Cholesterol	0.8	1.2	1.4	-1.0	1.2
Allergy or Eczema	0.8	2.2	2.7	-1.6	1.3
Type 2 Diabetes (T2D) (2018)	0.8	1.6	2.5	-1.6	0.8
Past tobacco smoking	0.8	1.5	2.0	1.4	-1.0
Had other major operations	0.8	1.0	2.0	-1.4	0.2
Asthma	0.8	1.6	2.0	-1.4	1.1
Headache pain in last month	0.8	1.3	1.6	1.3	-1.0
Neck or shoulder pain in last month	0.8	1.2	2.3	0.1	-1.5
Heart disease (mother)	0.8	1.0	1.3	0.9	-1.1
Leg pain on walking	0.8	1.0	1.1	0.9	-1.1
Age started oral contraceptive pill	0.8	0.9	1.1	1.1	-0.9
Blood Eosinophil Count	0.7	5.3	7.7	1.7	-2.8
Hearing difficulty/problems: Yes	0.7	1.1	1.6	1.2	-0.8
Age when periods started (menarche)	0.7	1.6	2.3	-0.9	1.5
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	2.7	1.5	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	2.4	1.6	-1.4
Number of children fathered	0.7	0.8	1.7	-1.3	-0.1
Pulse wave peak to peak time	0.7	0.8	1.2	1.1	-0.7
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.4	1.2	-0.5
Back pain experienced in last month	0.7	1.0	1.5	1.2	-0.8
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.5	1.2	0.4
Myopia	0.7	1.1	1.4	-0.8	1.2
Primary Biliary Cirrhosis	0.6	0.8	1.6	-1.2	0.4
Respiratory disease	0.6	1.2	2.2	-1.5	0.5
Hair Pigment	0.6	18.2	21.9	-4.7	3.8
Hand grip strength (left)	0.6	1.6	2.6	-1.6	0.8
Medication for hormone replacement therapy	0.6	0.6	0.8	0.9	-0.6
High blood pressure	0.6	1.5	1.7	-1.2	1.3
Hearing difficulty/problems with background noise	0.6	1.0	1.3	1.2	-0.8
Allergy	0.6	1.4	1.8	1.3	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	1.3	-1.1	0.1
Illnesses of mother	0.6	0.7	1.1	-1.0	0.5
Pulse wave Arterial Stiffness index	0.6	0.7	1.0	-1.0	0.7
Exposure to tobacco smoke at home	0.6	0.7	1.4	0.2	-1.2
Medication: Amlodipine	0.6	0.8	1.0	0.8	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	1.4	0.2	1.2
Average weekly red wine intake	0.6	0.9	1.2	-0.8	1.1
Alcohol drinker status: Never	0.6	0.8	1.2	1.1	-0.5
Ever depressed for a whole week	0.6	0.8	0.9	-1.0	0.8
Alcohol drinker status: Previous	0.6	0.7	1.1	-0.5	1.0
Verbal and Numeric Reasoning (VNR)	0.5	1.3	1.4	1.2	-1.1
Rheumatoid Arthritis	0.5	0.7	1.0	1.0	-0.6
Medication: Metformin	0.5	0.7	1.4	-1.2	0.2
Diabetes (father)	0.5	0.7	0.7	-0.8	0.8
Trunk fat percentage	0.5	2.0	2.6	1.6	-1.1
Chronic bronchitis/emphysema (father)	0.5	0.6	0.7	-0.7	-0.8
Leg predicted mass (left)	0.5	2.4	3.4	1.2	-1.9
Forced vital capacity (FVC)	0.5	1.9	2.0	1.4	-1.4
Arm fat mass (right)	0.5	2.2	2.4	1.4	-1.6
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	0.8	0.8	-0.9
Alcohol intake frequency.	0.5	1.2	1.7	1.3	-0.8
Suffer from ‘nerves’	0.5	0.8	1.2	1.1	-0.5
Illnesses of father: Heart disease	0.5	0.7	1.3	0.3	-1.1
Long-standing illness, disability or infirmity	0.5	0.8	0.9	-0.9	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.0	-1.0	-0.1
Qualifications: nursing, teaching	0.5	0.8	0.9	0.9	-0.9
Leg predicted mass (right)	0.5	2.4	3.5	1.1	-1.9
Arm fat mass (left)	0.5	2.0	2.1	1.4	-1.5
Number of self-reported non-cancer illnesses	0.5	0.8	1.2	-1.1	0.7
Reaction Time	0.4	0.8	1.6	-1.2	0.1
Neuroticism (2016)	0.4	0.6	0.8	0.6	-0.9
Average weekly spirits intake	0.4	0.4	0.7	-0.8	-0.5
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.0	-0.2	1.0
Leg fat-free mass (left)	0.4	2.2	3.3	1.1	-1.8
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	1.0	1.0	-0.9
Medication: Simvastatin	0.4	0.5	0.9	-1.0	0.4
Father’s age at death	0.4	0.6	0.7	0.7	-0.9
Prospective memory result	0.4	0.5	0.9	0.2	-1.0
Tense / ‘highly strung’	0.4	0.6	1.2	0.2	1.1
Forced vital capacity (FVC), Best measure	0.4	1.6	2.1	1.5	-1.1
Emphysema/chronic bronchitis	0.4	0.5	0.8	-0.9	-0.4
Had major operations	0.4	0.5	0.8	-0.4	0.9
Leg fat-free mass (right)	0.4	2.1	3.2	1.1	-1.8
Commuting to job workplace: Public transport	0.4	0.5	0.5	0.6	-0.7
Medication: Blood pressure	0.4	0.8	1.0	0.7	-1.0
Illnesses of father: High blood pressure	0.4	0.5	0.8	0.5	-0.9
Average weekly beer plus cider intake	0.4	0.6	1.1	0.1	-1.1
Cholesterol lowering medication	0.4	0.7	1.2	-1.1	0.3
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.7	0.9	0.6
Intelligence (Savage-Jansen 2018)	0.3	1.1	1.3	1.1	-0.9
Schizophrenia vs Biploar Disorder	0.3	0.4	0.8	-0.2	0.9
Blood White Count	0.3	2.6	3.9	-2.0	1.1
Angina	0.3	0.4	0.7	-0.8	0.2
Vitamin and mineral supplements	0.3	0.4	0.7	-0.8	0.3
Average weekly fortified wine intake	0.3	0.3	0.6	-0.1	0.8
Body mass index (BMI)	0.3	1.5	2.6	0.6	-1.6
Trunk fat mass	0.3	1.3	1.5	1.2	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.5	-0.6	0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.7	-0.1	0.9
Fluid intelligence score	0.3	0.6	0.9	0.5	-1.0
Pulse rate	0.3	0.5	0.8	0.5	-0.9
Length of working week for main job	0.3	0.3	0.6	-0.8	0.2
Birth weight of first child	0.3	0.6	0.8	0.9	-0.5
Gout (self-reported)	0.3	0.5	0.9	1.0	0.0
Body fat percentage	0.3	1.4	1.6	1.2	-1.1
Exposure to tobacco smoke outside home	0.3	0.4	0.8	0.3	-0.9
Medication: Omeprazole	0.3	0.3	0.6	0.2	0.8
Mean time to correctly identify matches	0.3	0.5	0.8	-0.9	0.4
Supplements: Vitamin C	0.3	0.4	0.7	0.8	-0.3
Knee pain experienced in last month	0.3	0.5	0.8	0.9	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.5	-0.7	0.5
Mother’s age at death	0.3	0.4	0.5	0.7	0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.4	-0.6	0.5
Neuroticism (Nagel 2018)	0.2	0.5	0.8	0.9	0.4
Alzheimer’s Disease (including proxy)	0.2	0.3	0.5	0.5	-0.7
Major Depression (MDD)	0.2	0.3	0.4	-0.6	0.4
Age at First Birth	0.2	0.3	0.7	0.8	-0.1
Lupus	0.2	0.3	0.3	0.5	-0.6
Triglycerides	0.2	0.4	0.4	-0.6	0.6
Blood Platelet Count	0.2	2.2	3.8	-1.9	0.8
Blood Red Count	0.2	2.0	3.1	-1.8	0.9
BMI	0.2	0.9	1.8	0.1	-1.4
Neuroticism	0.2	0.5	1.0	1.0	0.3
Systolic blood pressure, automated reading	0.2	0.5	0.8	0.3	-0.9
Medication: Co-codamol	0.2	0.2	0.3	0.5	-0.4
Had menopause	0.2	0.3	0.4	0.6	-0.5
Neuroticism score	0.2	0.5	0.8	0.9	0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.7	0.9	-0.2
High blood pressure (siblings)	0.2	0.2	0.4	0.7	-0.1
Arm fat-free mass (right)	0.2	1.1	2.2	-1.5	-0.1
Eye problems/disorders: None of the above	0.2	0.3	0.4	0.6	-0.4
Angina (self-reported)	0.2	0.3	0.6	-0.8	0.1
Medication: Allopurinol	0.2	0.3	0.6	0.8	0.1
Whole body fat mass	0.2	0.9	1.0	0.9	-1.0
Arm predicted mass (right)	0.2	1.1	2.2	-1.5	0.0
Age at last live birth	0.2	0.3	0.4	0.7	-0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.4	-0.1	0.7
Friendships satisfaction	0.2	0.2	0.4	0.6	0.1
Mineral and other dietary supplements	0.2	0.2	0.3	0.5	-0.5
Osteoarthritis (self-reported)	0.2	0.3	0.4	0.3	-0.6
Medication: Paracetamol	0.2	0.3	0.3	0.6	-0.5
Number of operations (self-reported)	0.2	0.3	0.5	-0.7	0.1
Commuting to job workplace: Cycle	0.2	0.2	0.3	0.6	-0.3
Impedance of whole body	0.2	1.2	1.5	1.0	1.2
Arm predicted mass (left)	0.2	0.9	1.7	-1.3	-0.2
Systolic Blood Pressure	0.1	0.3	0.5	-0.2	-0.7
Hypothyroidism (self reported)	0.1	0.2	0.4	0.6	-0.1
Lung FEV1/FVC ratio	0.1	0.5	0.5	0.7	-0.7
Chronotype (morning person)	0.1	0.1	0.3	-0.2	-0.5
Number of treatments/medications taken	0.1	0.2	0.2	-0.5	0.4
Hand grip strength (right)	0.1	0.2	0.3	-0.6	0.0
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	0.2	0.4
Serious illness, injury or assault to yourself	0.1	0.2	0.3	-0.6	0.1
Multivitamins +/- minerals	0.1	0.2	0.4	0.6	-0.1
Supplements: Glucosamine	0.1	0.2	0.4	0.6	0.1
Medication: Atenolol	0.1	0.1	0.2	-0.4	-0.2
Medication: Levothyroxine sodium	0.1	0.2	0.5	0.7	0.0
Number of incorrect matches in round	0.1	0.1	0.2	-0.1	0.4
Financial difficulties in last 2 years	0.1	0.2	0.2	-0.5	-0.3
Weight	0.1	0.7	1.2	0.4	-1.1
Trunk fat-free mass	0.1	0.3	0.4	-0.6	-0.5
Hip circumference	0.1	0.5	1.0	0.2	-1.0
Falls in the last year	0.1	0.1	0.3	-0.5	0.1
Happiness	0.1	0.1	0.1	0.4	0.2
Noisy workplace	0.1	0.2	0.3	-0.2	0.6
Medication: Lansoprazole	0.1	0.2	0.3	-0.2	-0.5
Trunk predicted mass	0.1	0.3	0.4	-0.6	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.4	-0.1
Medication: Paracetamol	0.1	0.2	0.3	0.4	-0.5
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.1	0.3	-0.3
Leg fat percentage (right)	0.1	0.3	0.5	-0.7	0.2
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.3	-0.6	-0.0
Medication for pain relief, constipation, heartburn	0.1	0.1	0.2	-0.4	-0.2
Comparative height size at age 10	0.1	0.5	0.9	1.0	-0.1
Overall health rating	0.1	0.3	0.6	0.7	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.4	-0.3	0.6
Whole body fat-free mass	0.1	0.5	1.0	-0.1	-1.0
Mood swings	0.1	0.1	0.2	-0.4	0.2
Ever had bowel cancer screening	0.1	0.1	0.1	0.3	-0.1
Commuting to job workplace: Walk	0.1	0.1	0.2	-0.5	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.2	0.1	-0.4
Medication for cholesterol	0.1	0.1	0.2	-0.1	0.4
Osteoporosis (self-reported)	0.1	0.1	0.2	-0.5	0.3
Whole body water mass	0.1	0.5	0.9	-0.1	-0.9
Wears glasses or contact lenses	0.1	0.1	0.3	0.5	0.1
Medication: Bendroflumethiazide	0.1	0.2	0.2	-0.2	-0.5
Medication: Lisinopril	0.1	0.1	0.1	-0.3	0.3
Basal metabolic rate	0.1	0.5	1.1	0.1	-1.0
Leg fat percentage (left)	0.1	0.2	0.5	-0.7	0.1
Arm fat-free mass (left)	0.1	0.8	1.4	-1.2	-0.4
Alzheimer’s Disease (in mother)	0.0	0.0	0.0	-0.2	0.2
Ovarian Cancer	0.0	0.0	0.0	-0.0	-0.1
Prostate Cancer	0.0	0.0	0.0	-0.0	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Heel T-Score	0.0	0.4	0.7	0.8	-0.3
Height	0.0	0.2	0.4	0.2	0.7
Pack years adult smoking proportion	0.0	0.0	0.0	0.1	0.1
Taking other prescription medications	0.0	0.0	0.0	0.0	-0.1
Sitting height	0.0	0.1	0.2	0.2	0.5
Waist circumference	0.0	0.2	0.2	-0.4	0.4
Alcohol usually taken with meals	0.0	0.1	0.1	-0.1	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.1	0.3	-0.0
Qualifications: None of the above	0.0	0.1	0.2	-0.4	-0.0
Alcohol intake versus 10 years previously	0.0	0.0	0.0	0.0	0.0
Depression (self-reported)	0.0	0.0	0.0	-0.2	0.1
Standing height	0.0	0.3	0.5	-0.2	0.7
Ever highly irritable/argumentative for 2 days	0.0	0.0	0.1	0.3	-0.0
Worry too long after embarrassment	0.0	0.0	0.0	0.2	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.0	-0.1	0.1
Leg fat mass (right)	0.0	0.1	0.2	-0.4	-0.1
Illnesses of siblings: Diabetes	0.0	0.0	0.1	-0.2	0.1
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.0	0.0	0.1
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.0	0.2	0.2
Irritability	0.0	0.1	0.1	-0.3	0.3
Unable to work because of sickness or disability	0.0	0.0	0.0	-0.2	0.0
Pack years of smoking	0.0	0.0	0.1	0.1	0.2
Leg fat mass (left)	0.0	0.1	0.1	-0.3	-0.3

Hub : Genes

SCAMP3

Models

Trait associations