Hub : Genes

SCAMP3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.045 0.021 0.0014 0.045 0.023 0.029 0.028 0.035 3.4e-06 0.00068 0.00015 0.00022 3.8e-05
2 GTEx Testis 0.087 0.042 0.0029 0.007 NA 0.013 NA 0.018 1.5e-01 NA 0.08200 NA 5.1e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 2.6 4.0 4.1 -2.0 2.0
Bipolar Disorder or Schizophrenia 4.7 11.4 15.5 -2.7 3.9
Depressed Affect (Nagel 2018) 1.4 2.9 4.1 -1.3 2.0
Depression (Nagel 2018) 1.0 1.5 2.0 -1.0 1.4
Intelligence (Savage-Jansen 2018) 0.3 1.1 1.3 1.1 -0.9
Neuroticism (Nagel 2018) 0.2 0.5 0.8 0.9 0.4
Schizophrenia (2018) 3.7 7.6 11.8 -1.9 3.4
Schizophrenia vs Biploar Disorder 0.3 0.4 0.8 -0.2 0.9
Worry (Nagel 2018) 2.9 6.0 9.6 3.1 -1.6
Alzheimer’s Disease (in mother) 0.0 0.0 0.0 -0.2 0.2
Alzheimer’s Disease (in father) 2.0 2.2 3.2 1.1 -1.8
Alzheimer’s Disease (including proxy) 0.2 0.3 0.5 0.5 -0.7
Crohns Disease (2017) 11.5 25.3 25.6 -5.1 5.0
Irritable Bowel Disease (IBD) 12.2 29.0 31.0 -5.6 5.2
Ulcerative Colitis (UC) 5.7 10.7 13.4 -3.7 2.8
Major Depression (MDD) 0.2 0.3 0.4 -0.6 0.4
Reaction Time 0.4 0.8 1.6 -1.2 0.1
Verbal and Numeric Reasoning (VNR) 0.5 1.3 1.4 1.2 -1.1
Breast Cancer 10.7 25.9 27.1 5.2 -5.0
Ovarian Cancer 0.0 0.0 0.0 -0.0 -0.1
Prostate Cancer 0.0 0.0 0.0 -0.0 -0.1
Age at First Birth 0.2 0.3 0.7 0.8 -0.1
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 1.7 2.3 3.4 1.1 -1.9
Coronary Artery Disease (CAD) 0.8 1.0 1.2 0.9 -1.1
Crohns Disease (2012) 18.1 29.2 32.6 -5.1 5.7
Mean Putamen Volume 3.2 3.7 5.7 -2.4 1.3
Fasting Glucose 1.8 2.1 3.6 -1.9 0.8
HbA1C 0.9 1.0 2.0 -1.4 -0.1
HDL Cholesterol 1.1 1.9 2.4 1.5 -1.2
LDL Cholesterol 0.8 1.2 1.4 -1.0 1.2
Lupus 0.2 0.3 0.3 0.5 -0.6
Neuroticism (2016) 0.4 0.6 0.8 0.6 -0.9
Primary Biliary Cirrhosis 0.6 0.8 1.6 -1.2 0.4
Rheumatoid Arthritis 0.5 0.7 1.0 1.0 -0.6
Schizophrenia (2014) 5.1 11.1 15.6 -2.6 4.0
Triglycerides 0.2 0.4 0.4 -0.6 0.6
Type 2 Diabetes (T2D) (2012) 1.4 1.6 1.6 -1.3 1.3
Ulcerative Colitis 4.4 6.4 7.1 -2.7 2.4
Blood Eosinophil Count 0.7 5.3 7.7 1.7 -2.8
Blood Platelet Count 0.2 2.2 3.8 -1.9 0.8
Blood Red Count 0.2 2.0 3.1 -1.8 0.9
Blood White Count 0.3 2.6 3.9 -2.0 1.1
Heel T-Score 0.0 0.4 0.7 0.8 -0.3
BMI 0.2 0.9 1.8 0.1 -1.4
Height 0.0 0.2 0.4 0.2 0.7
Waist Hip Ratio (WHR) 1.0 4.6 8.3 -0.9 2.9
Systolic Blood Pressure 0.1 0.3 0.5 -0.2 -0.7
Smoking Status 2.7 6.5 8.0 -2.8 2.2
Allergy or Eczema 0.8 2.2 2.7 -1.6 1.3
Cardiovascular Disease 1.9 6.4 7.2 -2.7 2.3
Hypothyroidism (self reported) 0.1 0.2 0.4 0.6 -0.1
Respiratory disease 0.6 1.2 2.2 -1.5 0.5
Type 2 Diabetes (T2D) (2018) 0.8 1.6 2.5 -1.6 0.8
Lung FEV1/FVC ratio 0.1 0.5 0.5 0.7 -0.7
Lung FVC 1.3 6.5 8.2 2.9 -2.2
Neuroticism 0.2 0.5 1.0 1.0 0.3
Chronotype (morning person) 0.1 0.1 0.3 -0.2 -0.5
Hair Pigment 0.6 18.2 21.9 -4.7 3.8
Tanning 1.9 23.0 23.0 -4.8 4.8
Hand grip strength (left) 0.6 1.6 2.6 -1.6 0.8
Number of treatments/medications taken 0.1 0.2 0.2 -0.5 0.4
Average weekly spirits intake 0.4 0.4 0.7 -0.8 -0.5
Sensitivity / hurt feelings 1.4 2.4 4.4 2.1 -0.6
Frequency of depressed mood in last 2 weeks 1.4 1.9 2.3 -1.2 1.5
Hearing difficulty/problems: Yes 0.7 1.1 1.6 1.2 -0.8
Relative age of first facial hair 1.0 2.1 2.3 -1.5 1.4
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 1.0 -0.2 1.0
Ever used hormone-replacement therapy (HRT) 1.3 1.7 1.9 1.2 -1.4
Ever had hysterectomy (womb removed) 1.9 2.1 2.9 1.7 -1.2
Systolic blood pressure, automated reading 0.2 0.5 0.8 0.3 -0.9
Eye problems/disorders: Diabetes related eye disease 1.5 1.7 2.6 0.9 -1.6
Angina 0.3 0.4 0.7 -0.8 0.2
Medication for hormone replacement therapy 0.6 0.6 0.8 0.9 -0.6
Vitamin and mineral supplements 0.3 0.4 0.7 -0.8 0.3
Supplements: Zinc 0.9 1.0 1.4 0.8 -1.2
Medication: Co-codamol 0.2 0.2 0.3 0.5 -0.4
Medication: Metformin 0.5 0.7 1.4 -1.2 0.2
Diabetes (father) 0.5 0.7 0.7 -0.8 0.8
Diabetes (mother) 2.5 3.2 3.9 -1.6 2.0
Severe depression (siblings) 3.6 4.0 4.0 -2.0 2.0
Pack years adult smoking proportion 0.0 0.0 0.0 0.1 0.1
Impedance of leg (right) 1.1 5.3 7.1 -1.8 2.7
Leg fat-free mass (left) 0.4 2.2 3.3 1.1 -1.8
Trunk fat percentage 0.5 2.0 2.6 1.6 -1.1
Hand grip strength (right) 0.1 0.2 0.3 -0.6 0.0
Townsend deprivation index at recruitment 2.6 3.7 4.0 -1.9 2.0
Current tobacco smoking 3.4 5.6 6.3 -2.5 2.2
Average weekly fortified wine intake 0.3 0.3 0.6 -0.1 0.8
Maternal smoking around birth 2.7 3.8 4.2 -2.0 1.9
Fed-up feelings 1.1 2.0 3.1 -0.9 1.8
Frequency of unenthusiasm / disinterest in last 2 weeks 1.3 1.8 1.8 -1.4 1.3
Relative age voice broke 1.0 1.6 3.0 -1.7 0.2
Taking other prescription medications 0.0 0.0 0.0 0.0 -0.1
Age when periods started (menarche) 0.7 1.6 2.3 -0.9 1.5
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 0.1 0.2 0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.9 1.0 1.0 -0.9
Tinnitus: Yes, but not now, but have in the past 4.3 4.6 5.1 2.2 -2.0
Qualifications: CSEs or equivalent 3.9 5.1 5.8 -2.1 2.4
Serious illness, injury or assault to yourself 0.1 0.2 0.3 -0.6 0.1
High blood pressure 0.6 1.5 1.7 -1.2 1.3
Hayfever, allergic rhinitis or eczema 1.0 2.2 2.6 -1.6 1.4
Multivitamins +/- minerals 0.1 0.2 0.4 0.6 -0.1
Stomach or abdominal pain in last month 1.2 1.5 1.8 1.3 -1.1
Supplements: Glucosamine 0.1 0.2 0.4 0.6 0.1
Diverticular disease/diverticulitis (self-reported) 1.1 1.3 1.6 1.3 -1.0
Medication: Atenolol 0.1 0.1 0.2 -0.4 -0.2
Medication: Levothyroxine sodium 0.1 0.2 0.5 0.7 0.0
Sitting height 0.0 0.1 0.2 0.2 0.5
Chronic bronchitis/emphysema (father) 0.5 0.6 0.7 -0.7 -0.8
High blood pressure (mother) 3.2 4.5 4.7 2.1 -2.2
Body mass index (BMI) 0.3 1.5 2.6 0.6 -1.6
Impedance of leg (left) 1.3 6.4 8.6 -2.0 2.9
Leg predicted mass (left) 0.5 2.4 3.4 1.2 -1.9
Trunk fat mass 0.3 1.3 1.5 1.2 -1.0
Waist circumference 0.0 0.2 0.2 -0.4 0.4
Number of incorrect matches in round 0.1 0.1 0.2 -0.1 0.4
Past tobacco smoking 0.8 1.5 2.0 1.4 -1.0
Alcohol usually taken with meals 0.0 0.1 0.1 -0.1 0.3
Nervous feelings 4.0 7.4 12.1 3.5 -1.6
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 0.5 -0.6 0.7
Hearing difficulty/problems with background noise 0.6 1.0 1.3 1.2 -0.8
Hair/balding pattern: Pattern 2 4.3 5.5 7.3 -2.7 1.9
Had menopause 0.2 0.3 0.4 0.6 -0.5
Had other major operations 0.8 1.0 2.0 -1.4 0.2
Forced vital capacity (FVC) 0.5 1.9 2.0 1.4 -1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.0 0.0 0.1 0.3 -0.0
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 0.7 -0.1 0.9
Qualifications: None of the above 0.0 0.1 0.2 -0.4 -0.0
Financial difficulties in last 2 years 0.1 0.2 0.2 -0.5 -0.3
Mouth/teeth dental problems 2.6 4.0 5.7 2.4 -1.5
Heart attack 1.1 1.5 2.1 -1.5 0.9
Allergy 0.6 1.4 1.8 1.3 -1.0
Pain all over the body in last month 1.3 1.4 1.9 1.4 -1.0
Diabetes (self-reported) 1.8 2.8 4.3 -2.1 1.1
Hayfever/allergic rhinitis (self-reported) 0.9 1.2 1.2 -1.1 1.1
Medication: Ramipril 8.1 10.4 14.7 -3.8 2.5
Medication: Simvastatin 0.4 0.5 0.9 -1.0 0.4
Fluid intelligence score 0.3 0.6 0.9 0.5 -1.0
Illnesses of siblings 1.1 1.6 2.2 1.0 -1.5
Neuroticism score 0.2 0.5 0.8 0.9 0.3
Weight 0.1 0.7 1.2 0.4 -1.1
Impedance of arm (right) 1.1 4.9 9.6 3.1 -0.5
Arm fat percentage (right) 1.2 4.6 5.2 2.3 -2.0
Trunk fat-free mass 0.1 0.3 0.4 -0.6 -0.5
Hip circumference 0.1 0.5 1.0 0.2 -1.0
Time employed in main current job 2.1 2.5 2.8 1.4 -1.7
Alcohol intake versus 10 years previously 0.0 0.0 0.0 0.0 0.0
Father’s age at death 0.4 0.6 0.7 0.7 -0.9
Worrier / anxious feelings 1.9 3.6 5.2 2.3 -1.4
Frequency of tiredness / lethargy in last 2 weeks 1.0 1.6 2.4 -1.6 0.9
Falls in the last year 0.1 0.1 0.3 -0.5 0.1
Hair/balding pattern: Pattern 3 1.4 2.1 3.5 1.9 -0.9
Number of live births 0.9 1.3 2.2 -1.5 0.6
Forced expiratory volume in 1-second (FEV1) 0.7 2.5 2.7 1.5 -1.7
Pulse rate 0.3 0.5 0.8 0.5 -0.9
Happiness 0.1 0.1 0.1 0.4 0.2
Noisy workplace 0.1 0.2 0.3 -0.2 0.6
Qualifications: A levels/AS levels or equivalent 1.5 3.4 4.0 2.0 -1.6
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.6 1.3 -1.1 0.1
Mouth/teeth dental problems: Dentures 4.6 7.7 11.2 -3.4 2.0
Asthma 0.8 1.6 2.0 -1.4 1.1
Medication: Ibuprofen (e.g. Nurofen) 3.3 4.2 5.4 1.7 -2.3
Medication: Cholesterol lowering 2.1 3.3 4.5 -2.1 1.4
Depression (self-reported) 0.0 0.0 0.0 -0.2 0.1
Medication: Lansoprazole 0.1 0.2 0.3 -0.2 -0.5
Prospective memory result 0.4 0.5 0.9 0.2 -1.0
Lung cancer (father) 0.9 1.1 1.9 -0.5 1.4
Illnesses of mother 0.6 0.7 1.1 -1.0 0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.2 2.4 1.6 -1.4
Pulse wave Arterial Stiffness index 0.6 0.7 1.0 -1.0 0.7
Impedance of arm (left) 1.2 5.7 11.2 3.4 -0.3
Arm fat mass (right) 0.5 2.2 2.4 1.4 -1.6
Trunk predicted mass 0.1 0.3 0.4 -0.6 -0.4
Standing height 0.0 0.3 0.5 -0.2 0.7
Length of working week for main job 0.3 0.3 0.6 -0.8 0.2
Exposure to tobacco smoke at home 0.6 0.7 1.4 0.2 -1.2
Breastfed as a baby 2.2 2.7 3.2 -1.5 1.8
Tense / ‘highly strung’ 0.4 0.6 1.2 0.2 1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.1 0.1 0.2 0.4 -0.1
Hair/balding pattern: Pattern 4 1.2 2.9 3.3 1.8 -1.6
Birth weight of first child 0.3 0.6 0.8 0.9 -0.5
Peak expiratory flow (PEF) 0.9 2.1 3.4 0.9 -1.9
Pulse wave reflection index 1.0 1.2 1.5 -1.2 1.0
Ever highly irritable/argumentative for 2 days 0.0 0.0 0.1 0.3 -0.0
Loud music exposure frequency 2.7 2.9 4.2 2.0 -1.3
Qualifications: O levels/GCSEs or equivalent 0.5 0.7 0.8 0.8 -0.9
Mouth/teeth dental problems: Bleeding gums 1.4 1.9 2.4 -1.5 1.2
Blood clot in the leg (DVT) 1.2 1.5 1.6 -1.3 1.2
Medication: Paracetamol 0.1 0.2 0.3 0.4 -0.5
Headache pain in last month 0.8 1.3 1.6 1.3 -1.0
Medication for cholesterol, blood pressure or diabetes 6.0 9.9 10.3 3.2 -3.1
Glaucoma (self-reported) 1.0 1.1 1.9 0.6 -1.4
Gout (self-reported) 0.3 0.5 0.9 1.0 0.0
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 0.7 0.9 -0.2
Medication: Amlodipine 0.6 0.8 1.0 0.8 -1.0
Medication: Ventolin 100micrograms inhaler 0.1 0.1 0.1 0.3 -0.3
Birth weight 2.5 5.5 8.0 2.8 -1.7
Chronic bronchitis/emphysema (mother) 1.1 1.2 1.5 -1.2 1.0
High blood pressure (siblings) 0.2 0.2 0.4 0.7 -0.1
Forced vital capacity (FVC), Best measure 0.4 1.6 2.1 1.5 -1.1
Body fat percentage 0.3 1.4 1.6 1.2 -1.1
Leg fat percentage (right) 0.1 0.3 0.5 -0.7 0.2
Arm fat-free mass (right) 0.2 1.1 2.2 -1.5 -0.1
Exposure to tobacco smoke outside home 0.3 0.4 0.8 0.3 -0.9
Comparative body size at age 10 1.1 2.9 4.2 1.3 -2.1
Number of full brothers 5.1 6.5 7.6 -2.8 2.3
Worry too long after embarrassment 0.0 0.0 0.0 0.2 -0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.7 1.4 0.2 1.2
Wheeze or whistling in the chest in last year 1.4 2.6 3.0 -1.5 1.7
Number of children fathered 0.7 0.8 1.7 -1.3 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.0 0.0 0.0 -0.1 0.1
Age at first live birth 1.2 2.2 2.4 1.6 -1.4
Pulse wave peak to peak time 0.7 0.8 1.2 1.1 -0.7
Health satisfaction 1.8 2.3 2.8 1.7 -1.3
Shortness of breath walking on level ground 1.5 1.8 3.3 1.8 -0.5
Qualifications: College or University degree 2.7 8.6 10.6 3.3 -2.6
Eye problems/disorders: None of the above 0.2 0.3 0.4 0.6 -0.4
Mouth/teeth dental problems: Loose teeth 0.1 0.2 0.3 -0.6 -0.0
Emphysema/chronic bronchitis 0.4 0.5 0.8 -0.9 -0.4
Medication for pain relief, constipation, heartburn 0.1 0.1 0.2 -0.4 -0.2
Neck or shoulder pain in last month 0.8 1.2 2.3 0.1 -1.5
Medication: Blood pressure 5.4 9.6 11.7 -2.7 3.4
Angina (self-reported) 0.2 0.3 0.6 -0.8 0.1
Migraine (self-reported) 3.3 4.1 5.7 2.4 -1.6
Medication: Ibuprofen 3.0 3.6 5.2 1.4 -2.3
Medication: Allopurinol 0.2 0.3 0.6 0.8 0.1
Medication: Omeprazole 0.3 0.3 0.6 0.2 0.8
Medication: Seretide 50 evohaler 1.2 1.4 1.5 -1.1 1.2
Mean time to correctly identify matches 0.3 0.5 0.8 -0.9 0.4
Heart disease (mother) 0.8 1.0 1.3 0.9 -1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 10.7 12.7 12.9 -3.5 3.6
Whole body fat mass 0.2 0.9 1.0 0.9 -1.0
Leg fat mass (right) 0.0 0.1 0.2 -0.4 -0.1
Arm predicted mass (right) 0.2 1.1 2.2 -1.5 0.0
Pulse rate, automated reading 1.7 5.5 6.6 2.6 -2.1
Alcohol intake frequency. 0.5 1.2 1.7 1.3 -0.8
Comparative height size at age 10 0.1 0.5 0.9 1.0 -0.1
Number of full sisters 3.7 4.5 7.8 -2.8 1.1
Suffer from ‘nerves’ 0.5 0.8 1.2 1.1 -0.5
Overall health rating 0.1 0.3 0.6 0.7 -0.2
Chest pain or discomfort 2.3 3.2 4.4 -2.1 1.5
Had major operations 0.4 0.5 0.8 -0.4 0.9
Age at last live birth 0.2 0.3 0.4 0.7 -0.3
Family relationship satisfaction 2.4 3.0 3.9 -1.4 2.0
Leg pain on walking 0.8 1.0 1.1 0.9 -1.1
Qualifications: NVQ or HND or HNC or equivalent 7.2 8.7 9.3 -3.0 2.9
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.4 -0.1 0.7
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 1.4 1.2 -0.5
Medication: Aspirin 2.9 3.8 5.2 -1.6 2.3
Supplements: Vitamin C 0.3 0.4 0.7 0.8 -0.3
Knee pain experienced in last month 0.3 0.5 0.8 0.9 -0.5
Hypertension (Self-reported) 1.1 3.0 3.2 -1.7 1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 0.5 -0.7 0.5
Illnesses of father: Heart disease 0.5 0.7 1.3 0.3 -1.1
Illnesses of siblings: Diabetes 0.0 0.0 0.1 -0.2 0.1
Smoking status: Previous 1.1 1.6 2.3 -1.5 0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.2 0.4 -0.3 0.6
Whole body fat-free mass 0.1 0.5 1.0 -0.1 -1.0
Leg fat-free mass (right) 0.4 2.1 3.2 1.1 -1.8
Arm fat percentage (left) 1.1 4.6 5.5 2.4 -1.9
Average weekly red wine intake 0.6 0.9 1.2 -0.8 1.1
Handedness (chirality/laterality): Left-handed 0.0 0.0 0.0 0.0 0.1
Mood swings 0.1 0.1 0.2 -0.4 0.2
Loneliness, isolation 1.0 1.4 2.1 -0.9 1.4
Long-standing illness, disability or infirmity 0.5 0.8 0.9 -0.9 0.8
Ever had bowel cancer screening 0.1 0.1 0.1 0.3 -0.1
Diabetes diagnosed by doctor 1.6 2.6 4.5 -2.1 0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 1.0 -1.0 -0.1
Friendships satisfaction 0.2 0.2 0.4 0.6 0.1
Qualifications: nursing, teaching 0.5 0.8 0.9 0.9 -0.9
Commuting to job workplace: Walk 0.1 0.1 0.2 -0.5 -0.2
Eye problems/disorders: Cataract 1.4 1.7 2.0 -1.4 1.2
Mouth/teeth dental problems: Mouth ulcers 0.1 0.1 0.2 0.1 -0.4
Medication for cholesterol 0.1 0.1 0.2 -0.1 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 4.8 5.6 6.2 2.5 -2.2
Back pain experienced in last month 0.7 1.0 1.5 1.2 -0.8
Mineral and other dietary supplements 0.2 0.2 0.3 0.5 -0.5
Breast cancer (self-reported) 1.7 2.0 2.2 -1.5 1.3
Asthma (self-reported) 1.0 2.0 2.5 -1.6 1.2
Osteoporosis (self-reported) 0.1 0.1 0.2 -0.5 0.3
Osteoarthritis (self-reported) 0.2 0.3 0.4 0.3 -0.6
Medication: Aspirin 3.7 4.9 5.9 -2.0 2.4
Medication: Gliclazide 2.4 2.7 3.1 -1.5 1.8
Illnesses of father: None of the above (group 1) 2.0 2.5 2.9 -1.5 1.7
Smoking status: Current 1.9 3.0 3.5 -1.9 1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.3 2.7 1.6 -1.4
Whole body water mass 0.1 0.5 0.9 -0.1 -0.9
Leg predicted mass (right) 0.5 2.4 3.5 1.1 -1.9
Arm fat mass (left) 0.5 2.0 2.1 1.4 -1.5
Number of self-reported non-cancer illnesses 0.5 0.8 1.2 -1.1 0.7
Average weekly champagne plus white wine intake 1.4 1.9 2.0 1.3 -1.4
Miserableness 2.9 5.1 6.5 -1.9 2.5
Guilty feelings 1.0 1.5 1.5 -1.2 1.2
Wears glasses or contact lenses 0.1 0.1 0.3 0.5 0.1
Ever taken oral contraceptive pill 1.2 1.3 1.3 -1.2 1.1
Hearing aid user 0.9 1.0 1.2 1.1 -0.9
Mother’s age at death 0.3 0.4 0.5 0.7 0.5
Financial situation satisfaction 5.6 6.9 7.7 -2.8 2.5
Tinnitus: Yes, now most or all of the time 1.1 1.3 1.6 1.2 -1.0
Commuting to job workplace: Public transport 0.4 0.5 0.5 0.6 -0.7
Eye problems/disorders: Glaucoma 0.9 1.0 1.2 0.9 -1.1
Medication: Blood pressure 0.4 0.8 1.0 0.7 -1.0
Pain type(s) experienced in last month: Hip pain 0.3 0.3 0.4 -0.6 0.5
Supplements: Fish oil (including cod liver oil) 0.0 0.0 0.0 0.2 0.2
High cholesterol (Self-reported) 1.7 3.1 5.5 -2.3 0.9
Medication: Bendroflumethiazide 0.1 0.2 0.2 -0.2 -0.5
Medication: Paracetamol 0.2 0.3 0.3 0.6 -0.5
Medication: Lisinopril 0.1 0.1 0.1 -0.3 0.3
Medication: Atorvastatin 4.3 5.3 7.5 -2.7 1.8
Illnesses of father: High blood pressure 0.4 0.5 0.8 0.5 -0.9
Alcohol drinker status: Never 0.6 0.8 1.2 1.1 -0.5
Ever smoked 1.0 1.7 2.1 -1.5 1.2
Basal metabolic rate 0.1 0.5 1.1 0.1 -1.0
Leg fat percentage (left) 0.1 0.2 0.5 -0.7 0.1
Arm fat-free mass (left) 0.1 0.8 1.4 -1.2 -0.4
Number of operations (self-reported) 0.2 0.3 0.5 -0.7 0.1
Average weekly beer plus cider intake 0.4 0.6 1.1 0.1 -1.1
Irritability 0.0 0.1 0.1 -0.3 0.3
Risk taking 2.5 3.6 3.9 -2.0 1.8
Ever had prostate specific antigen (PSA) test 0.7 0.8 1.5 1.2 0.4
Fractured/broken bones in last 5 years 1.1 1.4 2.4 -1.6 0.7
Age started oral contraceptive pill 0.8 0.9 1.1 1.1 -0.9
Diastolic blood pressure, automated reading 1.8 5.5 7.1 1.9 -2.7
Ever depressed for a whole week 0.6 0.8 0.9 -1.0 0.8
Unable to work because of sickness or disability 0.0 0.0 0.0 -0.2 0.0
Commuting to job workplace: Cycle 0.2 0.2 0.3 0.6 -0.3
Myopia 0.7 1.1 1.4 -0.8 1.2
Vascular/heart problems diagnosed by doctor 1.0 2.8 2.9 1.7 -1.7
Cholesterol lowering medication 0.4 0.7 1.2 -1.1 0.3
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 0.7 0.9 0.6
Pain experienced in last month 5.6 9.4 11.1 -3.3 2.8
Supplements: Calcium 1.0 1.1 1.4 -0.9 1.2
Basal cell carcinoma (self-reported) 2.9 3.4 3.6 1.9 -1.8
Heart attack/myocardial infarction (self-reported) 0.9 1.2 2.0 -1.4 0.6
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 1.6 -1.3 1.0
Heart disease (siblings) 1.1 1.4 1.8 -1.0 1.4
Alcohol drinker status: Previous 0.6 0.7 1.1 -0.5 1.0
Pack years of smoking 0.0 0.0 0.1 0.1 0.2
Impedance of whole body 0.2 1.2 1.5 1.0 1.2
Leg fat mass (left) 0.0 0.1 0.1 -0.3 -0.3
Arm predicted mass (left) 0.2 0.9 1.7 -1.3 -0.2