TWAS hub - CROCCP2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.688	0.0410	0.0e+00	0.312	0.385	0.393	0.342	0.362	1.1e-38	1.3e-49	6.2e-51	4.5e-43	4.7e-46
2	GTEx	Adipose Subcutaneous	0.115	0.0490	7.0e-03	0.027	NA	0.001	NA	0.009	2.5e-03	NA	2.8e-01	NA	5.1e-02
3	GTEx	Artery Aorta	0.304	0.0820	1.1e-05	-0.004	NA	0.094	NA	0.014	6.3e-01	NA	7.7e-06	NA	5.4e-02
4	GTEx	Artery Tibial	0.199	0.0732	8.0e-04	-0.003	NA	-0.003	NA	-0.004	8.4e-01	NA	6.1e-01	NA	9.6e-01
5	GTEx	Brain Caudate basal ganglia	0.314	0.1150	6.2e-03	0.048	NA	0.065	NA	0.073	1.7e-02	NA	6.2e-03	NA	4.0e-03
6	GTEx	Brain Cerebellar Hemisphere	0.281	0.1330	7.1e-03	0.016	NA	0.028	NA	0.015	1.2e-01	NA	6.4e-02	NA	1.3e-01
7	GTEx	Cells Transformed fibroblasts	0.348	0.0900	9.2e-06	-0.001	NA	0.057	NA	0.032	4.0e-01	NA	4.3e-05	NA	2.0e-03
8	GTEx	Esophagus Mucosa	0.198	0.0680	2.5e-04	0.077	NA	0.065	NA	0.066	7.9e-06	NA	3.7e-05	NA	3.3e-05
9	GTEx	Pancreas	0.406	0.1530	1.7e-03	-0.001	NA	0.098	NA	0.014	3.4e-01	NA	6.1e-05	NA	8.3e-02
10	GTEx	Skin Sun Exposed Lower leg	0.152	0.0530	7.8e-04	-0.003	NA	-0.001	NA	0.003	6.5e-01	NA	3.6e-01	NA	1.6e-01
11	GTEx	Whole Blood	0.150	0.0700	7.3e-04	0.010	NA	0.065	NA	0.048	3.6e-02	NA	1.3e-06	NA	3.2e-05
12	METSIM	Adipose	0.340	0.0573	0.0e+00	0.112	0.196	0.180	0.190	0.162	2.2e-16	1.3e-28	4.0e-26	1.0e-27	1.6e-23
13	ROSMAP	Brain Pre-frontal Cortex	0.635	0.0521	0.0e+00	0.097	0.295	0.329	0.293	0.228	1.8e-12	2.3e-38	1.9e-43	4.7e-38	8.1e-29

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Lung FEV1/FVC ratio	4.4	22.1	92.2	0.9	0.5	-4.4	-3.0	-4.1	-4.2	-4.0	-0.6	-4.8	-9.3	-9.6	2.0	0.1
Vitamin and mineral supplements	4.4	6.0	11.0	1.8	2.3	2.8	1.6	2.2	2.4	2.7	3.3	2.8	2.5	2.9	1.6	2.1
Mineral and other dietary supplements	3.5	4.7	10.2	1.2	2.1	2.2	1.8	2.4	1.8	2.6	1.8	2.2	3.2	2.4	1.3	2.4
LDL Cholesterol	3.0	4.7	17.3	-0.1	2.6	1.9	0.5	2.3	2.8	2.1	1.3	1.0	2.8	4.2	2.1	0.9
Heel bone mineral density (BMD) T-score, automated (right)	2.9	6.7	22.6	-2.3	-2.1	-1.3	-0.9	-3.2	-4.0	-3.0	-1.8	0.2	-1.7	-4.8	-2.6	-2.1
Multivitamins +/- minerals	2.8	3.6	6.0	-2.0	-0.9	-2.5	-1.9	-1.6	-2.0	-2.5	-2.2	-1.5	-1.8	-2.2	-0.9	-1.9
Knee pain experienced in last month	2.7	4.1	9.1	-1.7	-3.0	-2.1	-1.7	-1.0	-1.9	-1.9	-2.1	-0.4	-2.0	-2.7	-2.0	-2.6
Neuroticism (2016)	2.5	3.6	16.5	2.2	1.3	1.4	4.1	1.2	1.7	1.7	1.8	0.3	0.3	1.3	1.7	2.7
Ever highly irritable/argumentative for 2 days	2.5	3.0	10.4	0.1	-1.2	-2.1	-1.2	-0.7	-1.3	-1.8	-1.1	-1.4	-2.9	-3.2	-1.4	-1.4
Hayfever/allergic rhinitis (self-reported)	2.4	3.1	8.8	1.5	3.0	1.3	2.2	-0.3	0.1	2.2	2.6	0.8	1.0	1.1	1.4	2.6
Hair/balding pattern: Pattern 4	2.4	5.7	11.7	-1.4	-1.8	-3.0	-2.5	-2.6	-1.5	-3.3	-2.6	-2.3	-1.3	-2.5	-1.3	-3.4
Prospective memory result	2.3	2.8	7.6	0.0	-0.6	-1.7	-2.1	-1.8	-2.2	-1.7	-1.5	-2.2	-2.8	-1.5	-0.4	-0.3
Alcohol intake versus 10 years previously	2.2	3.2	11.6	-1.0	-3.1	-1.6	-1.5	-1.2	-1.0	-1.2	-3.4	-0.4	-1.7	-1.4	-0.7	-2.3
Average weekly fortified wine intake	2.1	2.5	8.4	0.1	1.7	1.1	0.9	1.7	1.0	2.0	0.8	1.8	2.9	2.2	0.9	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.5	6.1	-1.8	0.5	-2.5	-1.0	-1.6	-1.3	-1.5	-1.1	-2.3	-0.9	-1.8	-1.5	-1.6
Illnesses of father: High blood pressure	2.1	2.6	7.2	-0.0	0.6	1.9	0.8	2.1	2.7	1.3	0.6	1.7	2.5	1.4	1.7	1.3
Medication for hormone replacement therapy	2.0	2.2	5.6	1.4	1.7	2.4	1.8	1.5	1.5	1.6	0.9	1.1	1.2	1.5	0.1	1.5
Qualifications: College or University degree	2.0	6.2	17.2	4.2	1.5	3.1	2.5	2.1	1.4	3.3	2.4	2.1	0.8	1.7	1.9	3.2
Medication: Atorvastatin	2.0	2.5	6.6	0.7	2.6	1.9	1.1	1.7	2.0	1.2	1.3	0.9	0.9	1.5	1.9	1.6
Nervous feelings	1.9	3.5	8.2	1.3	2.0	1.4	2.9	1.8	1.9	1.7	1.3	-0.8	1.7	2.3	1.8	2.5
Chronic bronchitis/emphysema (mother)	1.9	2.2	7.3	-1.3	-0.3	-1.9	-0.8	0.2	-0.5	-1.8	-0.8	-0.5	-2.3	-2.7	-1.6	-1.7
Breast cancer (self-reported)	1.9	2.3	6.5	2.5	1.0	2.2	1.0	1.5	2.3	1.6	1.2	0.9	0.4	1.0	1.4	1.1
Commuting to job workplace: Public transport	1.9	2.3	5.8	1.6	0.8	1.4	0.7	2.4	2.3	1.4	0.4	1.1	2.4	0.9	1.6	0.9
High cholesterol (Self-reported)	1.9	3.4	9.9	0.7	1.9	1.2	1.8	1.4	2.3	1.9	1.3	-0.5	1.8	3.1	2.4	2.0
Ovarian Cancer	1.8	2.4	5.3	-1.0	-1.7	-2.0	-1.7	-1.3	-1.2	-0.9	-1.3	-1.8	-2.3	-2.3	-0.4	-1.3
Height	1.8	35.0	176.9	2.4	2.1	6.7	3.6	4.9	4.5	6.2	1.0	5.7	13.3	9.0	1.4	3.4
Eye problems/disorders: Diabetes related eye disease	1.8	1.9	4.7	-1.6	-1.0	-2.2	-1.2	-1.6	-2.0	-1.4	-0.8	-0.7	-1.1	-1.8	-1.1	-0.9
Medication: Co-codamol	1.8	2.1	6.1	-1.7	-2.5	-1.0	-0.3	-0.7	-0.8	-1.0	-2.3	-0.6	-0.6	-1.5	-1.9	-1.8
Maternal smoking around birth	1.8	2.6	8.2	1.1	2.3	2.0	2.9	0.4	0.8	1.6	1.6	1.7	0.7	1.5	1.6	0.8
Illnesses of father: None of the above (group 1)	1.8	2.2	4.9	-0.7	-1.0	-2.2	-1.1	-1.8	-0.9	-2.1	-1.3	-2.2	-1.7	-1.1	-0.5	-1.2
Forced vital capacity (FVC)	1.7	6.6	27.0	1.4	-1.2	2.8	1.4	1.2	2.9	1.8	0.1	2.1	5.2	5.0	-1.4	0.4
Fluid intelligence score	1.7	3.5	5.7	0.8	0.8	1.7	1.8	1.9	2.4	2.0	1.7	2.3	2.2	1.7	2.3	2.1
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.6	18.4	0.2	0.1	1.5	1.7	2.0	1.7	2.0	0.6	2.5	4.3	2.3	0.5	0.6
Bipolar Disorder (2018)	1.6	2.6	7.5	0.3	2.1	1.5	1.9	0.9	0.3	2.4	2.7	1.4	-0.1	1.0	2.1	1.3
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.6	14.0	-1.7	-1.3	-1.3	-0.2	-2.2	-2.4	-2.2	-2.0	0.4	-0.6	-3.7	-1.8	-1.8
Illnesses of siblings	1.6	2.2	8.3	-0.5	-0.1	-1.8	-0.3	-2.9	-2.6	-1.9	1.3	-0.5	-1.4	-1.6	-0.9	0.1
Forced vital capacity (FVC), Best measure	1.6	5.8	29.1	0.6	-1.2	2.5	0.8	1.0	2.4	1.4	0.0	2.2	5.4	4.5	-1.8	-0.3
Eye problems/disorders: None of the above	1.6	1.9	6.5	2.6	0.8	0.5	0.1	1.4	1.0	1.4	-0.6	-1.6	-0.6	0.4	2.0	2.1
Eye problems/disorders: Cataract	1.6	1.8	7.8	-0.6	-0.1	1.1	-0.3	-1.3	-0.4	-1.4	1.3	2.8	0.7	0.0	-2.0	-2.1
Cholesterol lowering medication	1.6	2.3	11.3	0.6	0.9	1.3	1.1	1.1	1.4	1.4	1.3	0.1	1.7	3.4	1.6	1.4
Cardiovascular Disease	1.5	4.8	12.0	-0.4	2.8	1.7	1.8	2.4	3.0	1.6	2.0	0.1	3.5	2.9	2.2	1.4
Lung FVC	1.5	7.6	30.3	0.7	0.1	4.4	2.7	0.7	2.7	1.8	2.0	2.1	4.0	5.5	-2.4	0.4
Severe depression (siblings)	1.5	1.7	5.7	-1.1	-1.6	-1.5	-0.6	0.8	0.3	-0.4	-1.9	-1.0	-0.4	-2.4	-0.8	-2.0
Hand grip strength (right)	1.5	4.1	11.2	1.3	1.1	2.3	2.3	1.7	1.6	2.6	0.7	3.4	3.3	1.6	0.6	1.8
Commuting to job workplace: Walk	1.5	1.7	4.1	1.4	1.0	1.0	1.4	1.0	1.3	1.8	0.2	0.5	1.0	1.8	1.2	2.0
Number of self-reported non-cancer illnesses	1.5	2.5	5.2	0.7	2.3	1.9	1.1	1.9	1.9	1.7	0.9	-0.0	0.9	2.2	2.0	1.4
Fractured/broken bones in last 5 years	1.5	2.0	6.5	1.1	2.0	0.7	1.0	-0.1	0.3	2.1	1.4	0.9	0.2	1.8	2.5	1.4
Rheumatoid Arthritis	1.4	2.0	6.0	0.0	0.3	1.1	0.8	1.3	1.6	1.4	0.7	0.1	2.5	2.2	1.1	2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	4.1	1.0	1.7	1.4	1.5	1.4	0.9	2.0	1.1	0.8	1.3	1.1	0.9	1.6
Medication for pain relief, constipation, heartburn	1.4	2.4	6.8	2.4	0.5	0.9	0.5	1.5	1.5	2.6	0.8	1.1	1.2	2.2	1.0	1.9
Long-standing illness, disability or infirmity	1.4	2.1	4.9	0.2	2.2	1.5	1.6	0.1	0.4	1.9	2.1	0.6	1.5	2.1	1.5	1.0
Commuting to job workplace: Cycle	1.4	1.6	3.8	-0.2	1.1	-0.0	-1.9	-1.6	-1.6	-1.7	1.2	-1.6	-2.0	0.8	-0.0	0.2
Verbal and Numeric Reasoning (VNR)	1.3	3.1	4.9	0.8	2.1	1.6	1.8	0.6	0.9	1.9	2.1	2.0	1.7	2.1	2.1	2.2
HbA1C	1.3	1.5	4.5	-0.3	0.4	-1.6	-1.8	-2.1	-1.7	-0.4	-0.2	-1.7	-1.3	-1.0	0.1	0.1
Hair/balding pattern: Pattern 3	1.3	1.9	6.1	1.0	-0.9	-1.8	-1.7	-1.5	-1.8	-1.0	-0.5	-0.8	-2.5	-1.7	-0.8	-0.3
Qualifications: A levels/AS levels or equivalent	1.3	2.8	7.6	2.8	1.1	1.4	1.6	0.3	-0.5	1.9	2.6	0.8	0.5	2.3	1.2	2.3
Exposure to tobacco smoke at home	1.3	1.4	7.4	-0.7	2.7	1.0	-0.8	-0.1	-0.9	0.4	1.6	0.5	-0.0	1.6	1.6	-0.2
Headache pain in last month	1.3	2.3	6.8	-2.4	-0.8	-1.2	-0.5	-2.6	-1.9	-1.5	0.8	-1.9	-1.3	-0.6	-0.8	-1.4
Number of children fathered	1.3	1.4	4.0	-1.3	-1.4	-1.0	-0.7	-0.5	-0.7	-1.2	-1.2	0.1	-0.5	-1.5	-2.0	-1.9
Supplements: Vitamin C	1.3	1.6	4.4	-0.2	-1.9	-1.0	-0.7	-0.7	-1.0	-1.0	-1.0	-2.1	-2.1	-0.9	-1.4	-0.9
Qualifications: nursing, teaching	1.3	2.1	5.7	0.4	1.9	1.2	2.2	-0.2	-0.2	1.4	2.4	1.8	1.2	1.7	0.4	1.1
Supplements: Glucosamine	1.2	1.5	4.7	-1.1	-0.5	-1.1	-0.8	-1.3	-1.2	-1.3	-0.6	-1.8	-2.2	-1.4	-0.4	-1.0
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	6.2	-1.8	-0.1	-0.1	0.4	-2.0	-2.5	-0.7	0.5	-0.2	-0.9	-1.5	-1.0	-1.0
Emphysema/chronic bronchitis	1.2	1.4	4.2	0.3	1.5	1.0	2.0	-0.4	-0.8	1.6	1.1	0.6	-0.4	1.6	1.1	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	6.9	2.4	0.4	1.1	0.2	0.6	-0.0	0.5	-0.3	0.5	-2.6	-1.1	0.7	1.1
Alcohol intake frequency.	1.2	2.7	6.3	-2.5	-1.4	-1.1	-1.9	-2.0	-1.5	-1.9	-1.6	-1.6	-1.8	-1.0	-0.7	-1.8
Supplements: Fish oil (including cod liver oil)	1.2	1.6	4.5	0.4	-1.6	-0.8	-0.5	-1.6	-0.8	-1.2	-1.6	-1.3	-2.1	-1.5	-0.1	-1.0
Medication: Paracetamol	1.2	1.8	6.6	-1.7	-0.7	-0.8	-0.1	-1.9	-0.9	-2.6	-0.7	-1.6	0.1	-0.7	-1.5	-1.5
Triglycerides	1.1	1.8	3.4	0.4	1.2	1.5	1.4	1.8	1.9	1.6	0.0	0.6	1.0	1.5	1.8	1.4
Hand grip strength (left)	1.1	3.0	5.7	1.1	0.9	2.3	2.0	1.1	1.6	2.2	1.1	2.2	2.4	1.7	0.5	2.2
Ever used hormone-replacement therapy (HRT)	1.1	1.4	4.0	0.3	1.5	2.0	0.0	1.6	1.4	1.1	1.3	0.6	0.1	1.0	1.5	1.2
Lung cancer (father)	1.1	1.3	3.5	-1.5	1.3	-0.9	-0.7	-1.4	-1.3	-0.5	-0.1	-1.9	-0.9	-0.3	1.5	-1.1
Standing height	1.1	10.7	73.4	0.4	0.1	2.9	1.9	2.2	1.9	3.3	0.2	2.7	8.6	4.8	0.1	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.6	7.2	1.2	0.6	0.5	2.7	1.9	1.0	2.2	0.2	0.2	-0.4	0.1	1.0	1.0
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.8	-1.6	0.4	1.0	0.0	1.4	1.2	-0.0	0.6	2.0	-0.5	-1.3	0.2	-1.8
Number of full sisters	1.1	1.4	4.3	-2.0	-1.0	-1.3	-0.6	1.3	0.2	-0.5	-2.1	-0.7	0.3	-1.2	-0.8	-1.3
Had major operations	1.1	1.3	5.4	0.3	-0.6	0.7	1.4	2.3	1.3	1.2	-0.0	1.0	1.1	1.0	-1.5	-0.3
Medication for cholesterol	1.1	1.6	4.0	0.7	-1.1	-1.7	-1.9	-0.9	-1.1	-0.8	-1.8	-0.1	-1.2	-2.0	-1.1	-0.9
Heart disease (siblings)	1.1	1.4	3.8	0.2	0.3	1.3	1.2	1.4	0.8	1.9	-0.4	1.7	1.6	1.3	0.3	0.9
Alzheimer’s Disease (in father)	1.0	1.1	4.3	1.1	0.8	-0.7	-0.2	-1.3	-1.7	-0.2	-0.6	-1.1	-2.1	0.0	0.9	0.6
Heel T-Score	1.0	8.3	33.5	-0.5	-2.9	-2.6	-1.2	-2.7	-3.0	-2.8	-2.8	-1.9	-2.8	-5.8	-2.5	-2.7
Relative age of first facial hair	1.0	2.0	5.2	2.1	0.9	1.3	2.1	2.0	2.3	1.4	-0.7	0.2	0.1	0.1	1.0	1.7
Age when periods started (menarche)	1.0	2.4	5.2	1.0	0.8	2.3	2.2	1.2	1.6	1.9	0.0	1.1	2.2	1.8	1.0	1.1
Alcohol usually taken with meals	1.0	1.7	3.8	1.6	0.2	1.8	1.0	-0.3	0.1	1.6	2.0	1.8	1.4	1.4	0.2	0.8
Qualifications: None of the above	1.0	2.1	7.3	-2.7	-0.8	-0.6	-0.6	-1.3	-1.3	-1.5	-0.8	-0.8	-1.5	-1.6	-1.4	-2.2
Mouth/teeth dental problems: Dentures	1.0	1.7	6.5	-1.8	0.1	-1.1	-0.6	-1.2	-1.1	-0.8	-2.1	-2.5	-0.5	-0.6	0.8	-1.4
Pulse wave reflection index	1.0	1.2	3.5	1.0	-1.8	-0.5	-0.5	-1.3	-1.1	-0.7	-1.1	-0.8	-1.2	-0.8	-1.9	0.1
High blood pressure (siblings)	1.0	1.4	6.0	0.4	-0.1	1.6	0.2	2.2	2.4	0.7	-1.3	-0.4	0.2	1.0	0.7	-1.2
Average weekly champagne plus white wine intake	1.0	1.3	4.1	1.1	0.6	0.1	2.0	-1.0	-1.3	1.9	1.8	0.5	0.2	1.3	0.1	0.4
Wears glasses or contact lenses	1.0	1.1	2.3	-1.3	0.1	-0.8	-0.6	-1.2	-1.5	-1.2	-0.4	-1.4	-1.2	-0.9	-1.5	-0.4
Ever taken oral contraceptive pill	1.0	1.1	4.0	1.7	-1.1	0.8	1.2	1.8	2.0	-0.0	0.3	0.6	-0.6	-0.2	-0.5	0.5
Mother’s age at death	1.0	1.3	5.3	-0.2	-0.6	-1.4	-1.2	-0.6	-0.2	-1.3	-0.1	-2.3	-1.8	-0.9	-0.7	1.0
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	2.9	-1.1	1.3	1.3	1.1	1.5	0.4	0.2	1.7	1.3	-0.1	1.3	0.4	1.1
Pack years of smoking	1.0	1.4	8.5	-2.9	0.4	-0.8	-0.6	0.2	-0.4	-1.1	-0.1	-0.1	1.0	-0.3	-0.4	-2.5
Bipolar Disorder (2011)	0.9	0.9	2.2	0.2	0.0	0.6	0.6	1.4	0.4	1.5	1.1	1.1	-0.1	0.2	1.4	1.4
Body Mass Index (BMI) (2010)	0.9	1.3	4.8	-1.6	-0.2	-1.6	-1.0	-1.4	-1.5	-0.4	-0.5	-0.0	-0.4	-2.2	0.1	-0.9
Frequency of depressed mood in last 2 weeks	0.9	1.2	4.8	-0.6	-0.0	-1.6	0.5	-0.9	-1.3	-1.1	-0.9	-1.0	-1.4	-2.2	-0.5	-0.2
Systolic blood pressure, automated reading	0.9	2.6	7.1	1.3	1.6	1.7	0.6	2.7	2.6	1.2	0.7	0.5	1.6	1.8	1.7	1.0
Pack years adult smoking proportion	0.9	1.4	8.7	-3.0	0.2	-0.8	-0.3	0.3	-0.1	-1.0	-0.2	-0.3	1.3	-0.2	-0.3	-2.4
High blood pressure	0.9	2.6	5.7	0.0	2.2	0.9	1.5	2.2	2.4	0.5	1.2	-1.4	1.7	1.8	2.2	1.1
Sitting height	0.9	6.7	44.6	0.9	-0.3	2.5	1.8	1.8	2.1	2.5	0.2	2.6	6.7	3.1	0.4	1.2
Peak expiratory flow (PEF)	0.9	2.0	6.4	1.0	-0.8	-1.1	-0.6	-2.5	-1.5	-1.6	0.0	-1.1	-2.3	-2.3	-0.6	-0.0
Medication: Paracetamol	0.9	1.5	5.2	-1.0	-1.0	-0.9	-0.1	-1.3	-1.0	-2.3	-1.1	-1.7	-0.1	-0.8	-1.2	-1.5
Medication: Ventolin 100micrograms inhaler	0.9	1.1	3.8	-2.0	-0.1	-0.3	0.6	-1.9	-2.0	-0.6	0.4	0.2	-0.6	-0.3	-1.0	-0.9
Health satisfaction	0.9	1.1	4.4	-2.1	1.6	0.1	0.2	-1.5	-0.6	-0.0	1.6	0.3	0.3	1.0	-0.5	-1.0
Shortness of breath walking on level ground	0.9	1.1	4.5	-1.1	2.1	0.1	0.5	-0.6	-0.7	0.7	2.1	-0.2	0.8	1.1	0.6	0.4
Migraine (self-reported)	0.9	1.1	6.0	-0.4	0.7	0.3	0.7	-1.2	-0.8	1.1	2.5	0.3	0.2	1.6	-0.0	0.9
Commuting to job workplace: Car/motor vehicle	0.9	1.1	3.5	-1.3	-1.1	-1.1	-0.1	-1.2	-1.0	-1.1	0.0	-0.6	-0.1	-1.1	-1.9	-1.0
Risk taking	0.9	1.3	4.7	-0.6	1.4	0.4	1.2	-0.1	-1.1	1.8	0.5	2.2	1.4	0.7	0.9	-0.4
Myopia	0.9	1.4	3.8	-0.7	-1.9	-1.1	0.2	-1.0	-0.7	-1.4	-2.0	-0.9	-0.8	-1.4	-1.1	-0.6
Vascular/heart problems diagnosed by doctor	0.9	2.4	6.1	-0.0	-2.5	-0.7	-1.3	-1.8	-2.2	-0.4	-1.4	1.6	-1.9	-1.8	-1.9	-1.0
Basal cell carcinoma (self-reported)	0.9	1.1	3.5	0.1	0.2	1.1	1.3	-0.6	-0.2	1.6	1.4	1.9	1.0	1.1	-0.2	0.0
Depression (Nagel 2018)	0.8	1.2	4.6	-0.8	0.3	-1.4	-0.2	-0.5	-1.8	-1.3	-0.4	0.8	-0.8	-2.2	-0.7	-1.0
Schizophrenia vs Biploar Disorder	0.8	1.1	3.4	0.9	-1.2	-1.2	-1.3	-0.2	0.1	-0.8	-1.9	-1.3	-0.4	-1.3	-0.9	-0.4
Serious illness, injury or assault to yourself	0.8	0.9	3.2	-0.7	0.8	1.4	0.1	0.7	0.5	0.7	0.4	1.8	0.2	1.7	-0.4	-1.1
Had menopause	0.8	1.1	3.1	1.7	1.1	1.8	0.3	0.1	0.6	0.7	0.9	0.0	-0.4	1.2	0.6	1.7
Had other major operations	0.8	0.9	3.3	0.0	-1.4	0.1	-0.7	1.8	1.8	-0.4	-0.7	-0.9	0.3	-0.7	0.4	-1.0
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	3.6	-0.6	0.2	-0.7	0.3	-0.4	-1.4	-0.8	1.1	0.1	-1.3	-1.5	-0.9	-1.9
Length of working week for main job	0.8	0.8	3.2	-1.5	0.6	-1.2	1.8	-0.3	-0.1	-0.0	-0.6	-1.1	0.5	-1.1	0.7	-0.0
Age at last live birth	0.8	1.2	5.4	-0.5	-0.4	-1.1	-1.6	-0.8	-0.6	-1.2	-1.4	-2.3	1.0	-0.4	-0.8	0.4
Osteoporosis (self-reported)	0.8	1.0	5.5	0.6	0.1	0.7	-0.1	2.4	1.5	0.2	0.5	0.1	0.5	1.8	0.4	0.8
Tinnitus: Yes, now most or all of the time	0.8	0.9	4.5	0.7	0.3	0.8	0.5	-1.2	-0.4	-0.6	2.1	-1.3	-1.4	0.5	-0.6	-0.0
Eye problems/disorders: Glaucoma	0.8	0.9	6.2	-2.5	0.2	-0.9	-0.9	0.0	-0.3	-0.4	-0.4	-0.3	-0.1	-0.1	0.3	-1.9
Medication: Bendroflumethiazide	0.8	1.2	8.2	-1.2	0.6	-1.4	-1.0	0.4	0.2	-1.2	-0.2	-2.9	0.7	0.0	0.5	0.1
Age started oral contraceptive pill	0.8	1.0	4.7	1.2	0.2	1.2	0.4	0.2	0.7	1.0	0.9	-0.2	0.3	1.4	0.6	2.2
Ever depressed for a whole week	0.8	1.0	2.8	-0.4	-0.9	-1.2	-0.4	-0.9	-1.3	-0.0	0.5	0.3	-1.7	-0.9	-1.3	-1.6
Heart attack/myocardial infarction (self-reported)	0.8	1.0	4.0	-0.7	0.1	-1.0	-0.5	2.0	1.7	-0.9	-0.8	-1.2	-1.0	-0.8	-0.3	-0.6
Bipolar Disorder or Schizophrenia	0.7	1.7	4.1	-0.8	1.3	0.4	2.0	1.5	1.2	1.3	2.0	1.5	-1.0	-0.5	1.6	0.9
Intelligence (Savage-Jansen 2018)	0.7	2.3	5.9	0.6	1.4	1.6	1.7	0.2	0.0	1.8	1.5	1.5	1.1	1.7	2.4	1.9
Alzheimer’s Disease (including proxy)	0.7	1.0	2.1	0.8	1.1	-0.2	1.4	-1.4	-1.5	0.4	0.9	0.2	-1.4	0.4	0.8	0.9
Prostate Cancer	0.7	1.0	2.4	-0.1	-0.9	-1.0	-0.6	-0.4	-1.3	-0.6	-1.6	-1.2	-0.4	-0.9	-1.3	-1.3
Primary Biliary Cirrhosis	0.7	0.9	3.5	-1.4	-0.6	-1.1	-1.0	-0.7	-0.3	-1.9	0.5	-0.9	-0.2	-1.1	-1.0	-0.7
Systolic Blood Pressure	0.7	3.6	12.5	2.4	0.7	1.7	1.4	2.7	3.5	1.6	0.6	0.3	1.7	2.8	1.1	0.9
Allergy or Eczema	0.7	1.8	6.2	1.5	1.3	1.3	1.4	0.5	0.1	1.9	1.7	0.4	0.1	1.4	0.9	2.5
Respiratory disease	0.7	1.6	9.8	-3.1	0.2	-1.0	-0.6	-1.7	-1.8	-0.2	-0.1	0.1	-0.0	1.3	-0.8	-1.2
Average weekly spirits intake	0.7	0.8	3.0	0.1	-0.8	-0.8	-1.3	0.0	0.1	-1.3	-1.7	-0.8	-0.3	-0.4	-0.8	-1.4
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	3.1	-0.5	1.8	1.4	0.4	1.1	1.3	0.4	0.6	0.1	1.0	1.3	1.1	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	4.1	-0.4	0.7	-0.5	1.0	-0.8	-1.7	-0.3	-0.6	0.2	0.0	-2.0	-0.9	-0.8
Qualifications: CSEs or equivalent	0.7	0.9	2.0	-1.2	-1.2	-0.8	-0.8	-0.8	0.0	-0.9	0.3	0.9	1.4	-0.1	-1.0	-1.4
Hayfever, allergic rhinitis or eczema	0.7	1.6	6.5	1.6	1.5	1.2	1.4	-0.1	-0.5	1.4	1.3	-0.0	-0.2	1.1	0.6	2.5
Medication: Levothyroxine sodium	0.7	1.3	4.1	0.7	0.9	1.6	1.2	0.8	0.8	1.3	1.8	2.0	0.2	0.5	0.2	0.9
Waist circumference	0.7	2.7	17.9	-4.2	1.6	0.7	0.9	0.4	-0.1	-0.2	0.8	-0.6	3.1	0.6	-0.3	-1.5
Number of incorrect matches in round	0.7	1.2	4.6	1.0	0.3	0.9	-0.1	1.3	2.1	1.6	0.4	0.7	-0.2	1.3	1.3	0.8
Heart attack	0.7	0.9	2.7	-0.7	-0.1	-1.0	-0.5	1.6	1.4	-1.1	-0.6	-1.1	-1.0	-1.0	-0.5	-0.5
Hip circumference	0.7	2.9	13.7	-3.2	1.9	1.5	0.8	-0.0	-0.1	0.4	2.0	0.5	3.7	0.7	-0.1	-1.1
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	4.3	0.5	1.7	1.6	0.7	1.0	0.9	1.2	2.1	1.9	-0.2	0.5	0.2	0.4
Exposure to tobacco smoke outside home	0.7	0.9	3.7	-1.9	0.2	-1.0	-0.3	-1.1	-1.2	-0.8	-0.8	-0.8	0.5	-0.8	0.9	-0.8
Neck or shoulder pain in last month	0.7	1.0	3.7	-1.0	0.3	1.4	1.9	-0.8	0.3	0.7	1.0	0.8	1.0	1.5	-0.2	-0.2
Medication: Ibuprofen	0.7	0.8	2.7	-1.0	-0.3	0.6	1.1	-1.5	-1.6	-0.5	0.8	0.1	-0.1	-1.3	-0.9	-0.2
Medication: Omeprazole	0.7	0.9	3.5	-1.1	0.2	0.8	1.2	0.9	0.1	-0.4	1.9	1.1	-1.1	0.7	-0.5	0.7
Medication: Seretide 50 evohaler	0.7	0.8	1.9	-1.3	-0.1	-0.2	0.8	-1.4	-0.9	0.1	1.0	1.0	1.3	0.8	-0.8	-0.9
Comparative height size at age 10	0.7	4.1	34.0	-0.9	0.4	1.0	0.8	0.5	0.2	1.8	0.3	1.4	5.8	3.2	-0.5	0.4
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	3.6	0.3	-0.4	-1.1	-1.9	-0.8	-0.4	-1.4	-0.2	-1.6	-0.8	-0.4	0.5	-0.2
Hypertension (Self-reported)	0.7	2.0	4.2	-0.1	2.0	0.7	1.3	1.8	2.0	0.6	1.1	-1.3	1.5	1.8	1.7	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	4.2	-0.3	1.0	0.5	-0.1	0.9	0.2	0.2	2.0	1.4	-0.9	-0.2	-0.1	1.1
Medication: Lisinopril	0.7	0.8	2.8	0.2	0.9	-0.2	-1.0	-1.2	-0.4	0.4	0.9	-1.0	1.0	1.7	0.9	0.8
Ever smoked	0.7	1.2	7.2	0.4	2.7	1.4	0.5	0.0	-0.9	1.6	-0.3	0.4	0.2	0.3	1.7	0.3
Diastolic blood pressure, automated reading	0.7	2.3	9.5	-0.9	-1.0	0.6	1.1	2.7	3.1	-0.6	-0.2	0.5	2.4	0.6	-1.5	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.5	1.1	1.0	1.6	0.5	0.2	0.2	1.2	-0.1	0.0	1.2	1.0	1.4	0.8
Schizophrenia (2014)	0.6	1.2	3.7	0.6	0.9	0.3	1.3	0.3	1.0	1.0	1.8	1.0	-0.9	-0.7	1.2	1.9
BMI	0.6	3.4	15.9	-4.0	1.5	-0.6	-0.8	0.0	-0.3	-2.0	-0.2	-0.9	-0.5	-3.1	0.8	-3.2
Waist Hip Ratio (WHR)	0.6	2.6	12.4	-1.4	0.6	1.0	1.4	1.8	0.9	1.2	-1.0	-0.2	3.5	3.0	-0.6	-0.7
Smoking Status	0.6	1.3	4.0	-2.0	0.7	0.5	0.5	1.6	0.5	1.8	-0.6	2.0	0.9	0.1	0.8	-1.0
Angina	0.6	0.7	3.6	0.7	1.9	0.2	-0.7	0.7	0.6	0.0	-0.6	-1.1	-0.3	0.4	1.4	-0.4
Impedance of leg (right)	0.6	2.8	26.1	0.2	-0.1	0.8	0.2	0.7	0.4	2.1	-0.1	0.2	1.8	5.1	-0.8	0.8
Townsend deprivation index at recruitment	0.6	0.9	2.3	-1.5	-0.2	-0.5	-0.1	-0.1	-0.5	-1.2	-0.9	-1.1	-1.2	-1.5	-0.1	-1.2
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	3.3	-0.1	1.6	0.1	0.4	0.2	0.3	0.5	1.8	0.2	1.0	1.3	0.5	0.8
Medication: Atenolol	0.6	0.7	2.2	-0.0	0.6	0.0	0.0	1.0	1.3	0.2	-0.4	-1.2	1.5	0.5	1.3	0.4
Allergy	0.6	1.3	3.5	-0.2	-1.6	-1.3	-1.2	0.7	1.1	-1.7	-0.7	-0.1	-0.3	-1.9	-0.7	-1.4
Pain all over the body in last month	0.6	0.6	1.9	-0.4	0.4	0.9	-0.4	1.3	1.0	0.9	-0.1	0.3	1.0	1.4	0.3	-0.4
Father’s age at death	0.6	0.8	3.3	0.3	1.0	0.6	-1.8	-1.5	-1.5	-0.9	0.1	-0.2	-0.6	0.2	-0.2	0.6
Worrier / anxious feelings	0.6	1.1	3.6	0.6	1.0	0.3	1.6	0.3	1.0	0.6	1.8	-0.9	-0.2	0.9	0.5	1.9
Breastfed as a baby	0.6	0.7	1.8	0.0	0.5	1.2	1.3	0.9	1.3	1.0	-0.5	-0.0	1.3	-0.0	-0.1	0.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	2.5	1.0	-0.1	1.1	1.6	-0.1	-0.1	0.1	1.4	0.9	-0.9	0.6	0.3	0.9
Blood clot in the leg (DVT)	0.6	0.8	2.6	1.2	0.9	1.5	0.2	0.2	0.2	1.0	-0.8	-0.4	0.9	0.7	1.6	0.5
Suffer from ‘nerves’	0.6	1.0	3.2	0.7	-0.9	0.5	1.8	1.7	1.6	0.6	0.1	-0.4	0.8	0.1	-0.2	1.3
Leg pain on walking	0.6	0.8	2.7	-1.6	-0.5	-0.8	0.3	-0.6	-0.9	-0.0	0.8	-1.6	-0.7	-0.8	-0.7	0.7
Medication: Aspirin	0.6	0.8	2.2	-0.7	1.0	-0.3	-0.8	-1.4	-1.5	-1.3	0.0	-0.2	-0.9	-0.7	0.6	-0.5
Loneliness, isolation	0.6	0.8	3.2	0.8	-0.6	-0.4	0.8	-0.7	-1.3	0.9	0.2	-0.5	-1.8	-1.5	0.1	0.0
Ever had bowel cancer screening	0.6	0.7	2.2	-0.2	0.8	-0.1	-0.8	-0.7	-1.5	-0.3	1.0	1.2	-1.0	1.1	0.8	-0.1
Diabetes diagnosed by doctor	0.6	1.0	4.1	0.3	2.0	0.6	0.1	-0.7	-0.6	0.6	1.1	0.1	0.6	1.4	1.7	1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.5	-1.0	-0.7	-1.0	0.5	0.9	1.0	-0.0	-0.2	-0.7	1.6	0.1	0.2	0.1
Friendships satisfaction	0.6	0.8	4.3	-1.1	1.1	-0.2	0.2	-1.0	-2.1	0.1	0.9	0.5	-0.2	-0.2	-1.0	-0.8
Medication: Aspirin	0.6	0.8	2.5	-1.1	0.9	-0.2	-0.9	-1.6	-1.4	-1.3	0.0	-0.2	-0.9	-0.6	0.6	-0.8
Smoking status: Current	0.6	0.9	2.7	-1.6	-0.3	0.2	-0.3	1.6	0.9	1.0	-0.7	0.9	1.3	0.1	0.5	-1.0
Hearing aid user	0.6	0.6	2.4	-0.8	0.9	0.9	1.6	0.4	0.2	0.2	1.4	1.0	0.6	0.2	-0.0	-0.1
Pain type(s) experienced in last month: Hip pain	0.6	0.7	2.9	-0.9	-1.7	0.2	0.5	0.8	0.9	0.2	-0.8	0.4	0.6	0.1	0.5	-1.4
Age at First Birth	0.5	0.7	2.1	1.2	-0.5	-0.3	-1.1	-0.4	-0.8	-0.8	-0.8	-1.4	-0.7	-1.1	-0.6	0.3
Mean Putamen Volume	0.5	0.6	2.3	-1.3	0.8	-0.8	0.0	-0.6	-0.8	-0.7	1.5	0.3	-0.3	-0.4	-0.9	-0.3
Lupus	0.5	0.7	2.5	0.9	1.6	0.2	0.0	-0.1	-0.8	1.2	0.3	-0.8	0.3	0.7	1.2	1.1
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.7	-1.0	-0.7	0.3	1.4	-0.1	0.1	0.6	-0.3	-0.1	1.6	-0.8	0.4	0.2
Hypothyroidism (self reported)	0.5	1.1	4.7	0.5	1.9	1.3	0.0	0.8	0.6	0.7	2.2	1.1	-0.8	0.6	0.5	0.5
Number of treatments/medications taken	0.5	0.9	3.1	-1.8	0.2	0.2	-0.2	-0.6	-0.3	-1.4	0.0	-1.2	-0.9	-0.0	-1.0	-1.6
Diabetes (father)	0.5	0.7	5.0	-2.2	-0.9	-0.5	-0.1	-0.6	-0.6	0.2	0.3	0.1	-0.2	-0.2	-0.9	-1.0
Diabetes (mother)	0.5	0.7	2.1	-1.2	0.2	-0.8	-1.2	-0.6	-0.4	-0.7	-1.0	-1.5	0.4	-0.2	-0.7	0.7
Trunk fat percentage	0.5	2.1	12.7	-3.6	1.9	0.4	-0.1	-1.1	-1.1	0.0	1.1	-0.4	2.0	0.5	0.3	-1.7
Fed-up feelings	0.5	0.9	2.8	-1.4	0.1	-0.7	-0.5	-0.1	-0.2	-1.5	-0.8	-0.4	-0.6	-1.4	-1.0	-1.7
Chronic bronchitis/emphysema (father)	0.5	0.6	1.8	-0.7	1.1	0.9	-0.3	1.3	0.7	0.2	1.4	0.4	1.0	0.7	0.3	0.5
Impedance of leg (left)	0.5	2.4	21.4	0.3	-0.6	0.6	-0.0	0.4	-0.0	1.9	-0.9	0.2	1.3	4.6	-1.1	1.0
Trunk fat mass	0.5	2.0	10.1	-3.2	1.7	0.7	0.3	-0.7	-0.6	0.2	1.1	-0.1	2.9	0.5	0.3	-1.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	6.6	0.6	0.7	0.4	2.6	0.2	0.6	0.8	0.1	-0.2	0.3	0.4	0.4	0.4
Diabetes (self-reported)	0.5	0.8	2.8	0.1	1.6	0.6	-0.5	-0.5	-0.4	0.7	0.6	-0.4	0.3	1.4	1.7	0.9
Medication: Simvastatin	0.5	0.8	4.6	-0.7	-0.4	-1.0	-0.0	0.6	0.8	-0.6	-0.4	-2.1	-0.1	1.4	0.0	-0.1
Number of live births	0.5	0.7	2.0	-1.4	-0.6	-0.8	-0.6	1.2	1.0	-1.1	-0.2	0.3	0.9	-0.6	-0.2	-0.9
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	5.0	1.9	-1.1	1.7	0.7	-0.1	1.4	0.7	0.3	0.7	2.2	2.2	-0.8	0.8
Happiness	0.5	0.6	2.8	-1.7	-0.6	-0.7	-0.7	-0.8	-0.6	-0.5	-0.2	-0.7	-0.1	-0.2	-1.2	-1.0
Asthma	0.5	1.1	4.8	-2.2	0.7	0.4	0.7	-0.8	-0.9	0.9	0.3	1.2	0.3	1.9	0.1	-0.4
Medication: Cholesterol lowering	0.5	0.8	5.8	-0.3	0.8	-0.7	-0.6	0.2	0.6	-1.0	-0.4	-2.4	-1.2	0.0	0.5	0.1
Pulse wave Arterial Stiffness index	0.5	0.6	1.2	0.5	0.3	1.0	1.1	-0.6	-0.5	1.0	0.5	1.0	0.8	0.2	-0.9	0.7
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	1.9	1.2	-0.4	-0.7	0.1	-0.8	-1.4	1.0	0.7	-0.3	-0.2	1.2	0.4	1.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.3	-0.3	-1.5	-0.8	-1.0	-0.9	-1.5	-0.4	-0.3	1.1	0.0	-0.8	-0.5	-0.8
Body fat percentage	0.5	2.1	12.9	-3.6	1.9	0.3	-0.1	-1.2	-1.2	-0.3	1.0	-0.7	1.4	0.3	0.1	-1.9
Leg fat percentage (right)	0.5	1.7	10.6	-3.3	2.0	0.3	0.2	-0.7	-0.6	-0.1	1.3	-0.7	1.0	0.7	0.1	-1.8
Number of full brothers	0.5	0.6	2.2	0.5	0.1	0.4	1.0	0.3	-0.6	1.3	-1.0	0.3	-0.6	-0.3	0.8	1.5
Angina (self-reported)	0.5	0.7	2.9	0.4	1.7	0.2	-0.7	0.8	0.9	0.2	-0.5	-1.2	-0.1	0.6	1.3	-0.3
Heart disease (mother)	0.5	0.6	1.5	0.8	-0.6	0.7	0.3	1.2	1.2	0.8	-0.2	0.5	0.9	1.1	0.7	0.3
Leg fat mass (right)	0.5	1.8	9.4	-3.1	1.8	0.6	0.5	-0.4	-0.1	0.0	1.3	-0.3	2.2	0.3	0.3	-1.6
Pulse rate, automated reading	0.5	1.6	4.1	-1.5	-1.1	-2.0	0.3	-1.7	-0.6	-1.1	-0.2	-1.4	-1.0	-1.0	-1.5	-1.6
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.0	0.0	0.5	0.3	1.1	0.8	1.2	1.1	-0.0	1.1	1.4	-0.2	-0.1	-0.1
Arm fat percentage (left)	0.5	2.0	10.5	-3.2	1.7	0.0	-0.4	-1.4	-1.2	-0.8	1.4	-0.7	0.6	-0.8	0.3	-2.1
Asthma (self-reported)	0.5	1.0	5.1	-2.3	0.8	0.2	0.6	-0.8	-0.8	0.9	0.1	1.1	0.7	1.7	0.2	-0.5
Medication: Gliclazide	0.5	0.6	1.4	0.2	1.2	0.8	0.8	-0.1	-0.4	0.8	0.9	1.0	0.3	0.2	1.1	1.0
Financial situation satisfaction	0.5	0.6	2.4	-1.0	1.2	-0.9	-0.2	-1.5	-1.2	0.1	-0.1	-0.6	0.7	-0.4	-0.4	0.0
Unable to work because of sickness or disability	0.5	0.6	2.9	-1.5	0.6	-0.7	0.6	-0.1	-0.6	-0.6	0.9	-1.7	-0.5	0.4	-0.4	-0.1
Pain experienced in last month	0.5	0.9	4.5	1.3	1.5	0.4	-0.0	1.0	0.5	0.2	0.9	0.3	0.8	0.6	0.3	2.1
Supplements: Calcium	0.5	0.5	1.7	1.1	0.3	-0.6	-1.2	-0.8	-0.7	-0.0	0.7	-0.6	-1.3	0.1	-0.3	0.3
Depressed Affect (Nagel 2018)	0.4	0.9	2.2	-0.7	-0.3	-1.0	-1.2	-0.3	-1.2	-0.9	-0.6	0.2	-1.1	-1.2	-1.2	-1.5
Schizophrenia (2018)	0.4	0.8	1.9	-1.3	0.1	-0.7	1.1	1.2	1.3	-0.1	0.6	0.7	-1.1	-1.4	0.4	0.1
Worry (Nagel 2018)	0.4	0.9	3.8	0.5	0.3	0.4	1.3	0.1	0.3	0.4	2.0	-0.5	0.4	1.3	-1.3	1.5
Ulcerative Colitis (UC)	0.4	0.8	2.8	0.9	1.0	0.4	-0.1	-0.1	0.6	-0.4	1.4	0.6	1.7	1.3	0.4	0.9
Coronary Artery Disease (CAD)	0.4	0.5	2.2	-0.2	-0.1	0.1	-0.2	-1.5	-0.9	0.4	-0.1	-0.1	-1.1	1.0	0.5	-0.8
HDL Cholesterol	0.4	0.7	1.6	0.8	-1.2	0.6	1.1	1.1	1.2	-0.3	0.4	0.5	1.3	-0.0	-0.9	0.3
Type 2 Diabetes (T2D) (2018)	0.4	0.7	2.9	-0.7	1.7	0.0	-0.6	-0.2	-0.5	0.1	1.0	-0.2	0.8	1.4	0.9	0.6
Chronotype (morning person)	0.4	0.9	5.2	2.3	-1.5	0.2	-0.4	-1.0	0.1	0.1	-1.3	-0.4	-0.1	-0.6	-0.8	0.6
Ever had hysterectomy (womb removed)	0.4	0.5	2.5	0.4	-0.7	0.2	1.1	0.0	0.1	-0.5	-0.1	1.6	-0.7	-1.0	-0.1	-0.5
Current tobacco smoking	0.4	0.7	2.5	-1.6	-0.3	0.2	0.1	1.6	1.0	0.8	-0.6	0.3	1.0	0.3	0.3	-1.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.5	-0.1	-1.2	0.1	-0.1	0.4	0.5	-0.8	-1.1	-0.6	0.2	-1.1	0.0	-0.6
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.6	-0.1	-0.8	-0.9	-1.2	0.1	-0.3	0.1	-0.8	-0.7	-0.6	0.4	0.9	0.2
Stomach or abdominal pain in last month	0.4	0.5	2.4	-0.5	0.1	0.4	0.1	1.5	0.9	-0.3	-0.8	0.9	-0.3	-0.5	0.8	-0.4
Body mass index (BMI)	0.4	1.8	9.3	-3.0	1.4	-0.1	0.1	-0.8	-0.6	-1.3	1.0	-0.6	0.0	-2.2	0.3	-1.9
Hair/balding pattern: Pattern 2	0.4	0.5	2.5	-0.4	0.4	1.0	0.6	0.3	0.4	0.5	0.4	0.3	1.6	0.2	-0.8	1.1
Financial difficulties in last 2 years	0.4	0.5	1.9	-1.4	0.5	0.2	0.5	-0.6	-0.7	-0.8	0.7	0.4	-0.1	-0.6	0.0	-1.3
Mouth/teeth dental problems	0.4	0.5	1.9	1.1	0.4	-0.2	-0.4	-0.8	-0.8	-0.2	1.3	0.4	-0.1	-0.1	-1.4	0.8
Medication: Ramipril	0.4	0.5	2.2	-0.9	-0.0	-0.1	0.4	1.0	1.5	-0.0	-0.1	-0.7	0.6	-0.6	-0.8	0.1
Weight	0.4	2.2	14.0	-2.7	1.5	1.1	0.9	0.1	0.2	0.3	1.1	0.5	3.7	0.2	0.4	-1.0
Impedance of arm (right)	0.4	1.7	12.3	0.1	0.7	1.0	-0.4	0.2	-0.0	2.3	0.4	0.2	1.7	3.5	0.1	0.7
Arm fat percentage (right)	0.4	1.7	9.9	-3.2	1.8	0.2	-0.2	-1.2	-1.0	-0.5	1.2	-0.5	0.7	-0.7	0.4	-2.0
Time employed in main current job	0.4	0.5	2.6	-1.1	-0.6	-0.8	-0.7	-0.5	-0.8	0.0	-0.1	0.4	-0.5	-0.2	0.3	-1.6
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	4.3	-0.8	2.1	0.8	0.6	-0.2	-0.6	0.0	0.8	-0.1	0.2	0.6	1.0	-0.3
Pulse rate	0.4	0.7	2.5	-1.6	0.8	-0.9	0.8	-0.1	1.1	-0.2	0.1	-1.1	1.6	0.2	0.4	-0.1
Noisy workplace	0.4	0.4	2.8	-1.7	-0.2	-0.3	-0.4	0.3	0.4	-0.2	0.3	-0.2	0.2	-1.0	-0.6	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.5	0.1	-1.6	-0.3	0.8	0.0	0.1	0.1	-0.8	0.3	0.7	-0.3	-0.7	-1.2
Medication: Lansoprazole	0.4	0.5	1.8	-0.7	-0.6	-0.6	-0.8	0.7	0.8	-0.5	0.1	-1.3	-0.5	0.7	0.2	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	6.3	0.9	-1.2	1.4	0.3	0.0	1.4	0.2	0.3	1.0	2.5	1.8	-1.2	-0.0
Arm fat mass (right)	0.4	1.7	9.2	-3.0	1.7	0.8	0.4	-0.4	-0.2	-0.2	1.0	0.3	2.1	-0.6	0.5	-1.9
Tense / ‘highly strung’	0.4	0.7	2.9	0.2	0.3	0.4	1.7	-0.8	-0.7	-0.1	0.8	-0.3	-1.6	-0.5	-0.3	1.0
Birth weight	0.4	1.0	3.3	1.8	-0.0	0.8	-0.1	-1.1	-1.0	0.5	-1.6	0.1	0.6	-0.6	1.3	1.0
Worry too long after embarrassment	0.4	0.6	1.9	0.3	0.8	0.6	1.4	0.5	1.0	0.9	0.8	-0.3	0.7	0.4	0.9	0.7
Pulse wave peak to peak time	0.4	0.4	1.2	-0.4	-0.2	-0.8	-1.1	0.7	0.7	-0.7	-0.6	-0.8	-0.2	-0.0	1.0	-0.6
Medication: Blood pressure	0.4	0.6	4.4	0.5	0.7	-0.5	0.2	0.7	1.1	-0.4	-0.6	-2.1	-0.4	-0.1	0.1	0.6
Whole body fat mass	0.4	1.8	10.2	-3.2	1.5	0.4	0.2	-0.8	-0.7	-0.2	0.8	-0.3	2.5	0.2	0.2	-1.7
Overall health rating	0.4	0.9	6.4	-2.5	1.5	-0.0	-0.2	-0.1	-0.2	-0.1	0.9	-0.6	0.2	0.4	0.9	-0.9
Illnesses of siblings: Diabetes	0.4	0.5	1.7	-1.0	0.5	-0.2	-1.3	1.0	0.1	-0.2	-1.2	-0.2	1.1	0.1	0.6	-0.1
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.9	0.0	-0.0	-0.2	1.4	0.5	0.4	1.7	0.2	-0.4	0.7	0.4	0.3	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.2	0.2	-0.8	0.3	-0.2	1.1	1.0	1.0	-0.8	0.2	0.6	1.1	1.5	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	3.4	0.4	-0.9	1.6	0.5	1.2	1.8	-0.4	0.2	0.2	0.2	0.9	-1.4	-0.2
Arm fat mass (left)	0.4	1.7	10.1	-3.2	1.7	0.5	0.3	-0.7	-0.6	-0.5	1.2	-0.0	1.8	-0.7	0.3	-1.8
Guilty feelings	0.4	0.5	1.9	-0.2	1.1	0.1	1.1	-0.4	-0.5	0.9	0.8	-0.2	0.4	0.0	1.4	0.8
Leg fat percentage (left)	0.4	1.5	10.4	-3.2	1.7	0.2	0.1	-1.0	-1.0	-0.2	0.8	-0.5	0.6	0.3	-0.0	-1.8
Number of operations (self-reported)	0.4	0.5	2.5	-0.4	0.1	0.3	-0.2	1.6	1.1	0.4	-0.7	-0.9	-0.3	0.3	0.2	-1.1
Average weekly beer plus cider intake	0.4	0.6	1.9	-0.2	-0.9	0.2	-0.2	0.3	0.6	-1.1	-0.8	-0.1	-1.4	-0.2	-0.8	-1.3
Alcohol drinker status: Previous	0.4	0.5	2.7	-0.5	-0.1	-0.2	-0.7	-0.7	-0.6	-0.2	-1.2	-1.6	0.1	0.5	0.6	-0.4
Impedance of whole body	0.4	1.9	16.9	0.2	-0.1	0.7	-0.3	-0.2	-0.4	1.9	-0.1	0.3	1.5	4.1	-0.7	0.7
Leg fat mass (left)	0.4	1.5	8.6	-2.9	1.5	0.6	0.4	-0.3	-0.1	-0.1	0.9	-0.3	2.0	0.1	0.2	-1.6
Alzheimer’s Disease (in mother)	0.3	0.3	1.4	0.3	0.8	0.3	0.8	-0.4	-0.2	0.5	1.2	0.5	-0.0	0.2	0.2	0.6
Reaction Time	0.3	0.5	1.7	1.2	0.3	-0.2	-0.5	-1.3	-0.6	0.1	1.1	-0.2	-1.2	-0.2	0.4	0.3
Crohns Disease (2012)	0.3	0.4	1.4	0.5	-0.2	-0.4	-0.6	-1.2	-0.6	-0.7	0.4	-0.7	-0.4	-0.7	1.0	0.0
Fasting Glucose	0.3	0.4	2.5	0.3	-0.1	-0.9	1.6	0.2	-0.3	0.9	-0.2	-0.0	0.0	-0.2	-0.8	-0.2
Blood Red Count	0.3	3.0	7.3	-2.4	-1.8	-0.8	-1.2	-0.6	1.0	-1.2	-1.1	-1.1	2.5	2.0	-2.3	-2.7
Hearing difficulty/problems: Yes	0.3	0.5	3.9	-2.0	-0.4	0.3	0.4	-0.4	-0.2	-0.1	0.5	0.5	-0.9	-0.7	0.1	-0.3
Supplements: Zinc	0.3	0.4	0.8	-0.1	0.7	0.6	0.6	0.8	0.3	0.1	0.9	0.4	0.8	0.5	-0.9	0.2
Medication: Metformin	0.3	0.5	2.2	-0.2	1.5	0.4	-0.9	-0.7	-0.9	0.0	0.4	0.1	-0.7	0.3	0.9	0.2
Leg fat-free mass (left)	0.3	1.6	13.5	-1.4	0.8	0.7	0.9	0.1	0.4	0.0	1.0	0.6	3.7	-0.6	0.6	-0.8
Relative age voice broke	0.3	0.4	1.5	0.7	-0.6	0.1	0.0	0.3	-0.5	0.0	-1.1	-1.2	-1.2	-0.4	0.1	-0.2
High blood pressure (mother)	0.3	0.4	1.7	0.3	-1.1	-0.0	0.2	0.4	1.0	0.6	-0.5	0.1	0.3	1.3	0.9	-0.4
Leg predicted mass (left)	0.3	1.5	13.5	-1.4	0.7	0.7	0.8	0.1	0.4	0.0	1.0	0.7	3.7	-0.6	0.6	-0.8
Past tobacco smoking	0.3	0.6	2.9	-0.1	-1.7	-0.6	-0.4	-0.3	0.6	-1.0	0.6	-0.7	0.2	0.4	-1.2	0.0
Neuroticism score	0.3	0.5	2.4	0.5	1.1	0.2	1.5	1.0	0.6	0.7	0.9	-0.1	0.4	0.2	0.1	0.6
Trunk fat-free mass	0.3	1.8	16.1	-0.5	0.3	1.1	1.5	1.0	0.9	0.7	0.4	1.1	4.0	0.5	0.3	0.1
Falls in the last year	0.3	0.4	2.7	-1.7	0.3	-0.7	1.1	0.1	-0.4	0.5	0.4	-0.1	0.3	0.4	0.2	0.0
Depression (self-reported)	0.3	0.4	0.9	0.2	-0.0	-0.5	0.3	0.9	0.7	0.5	-1.0	-0.9	0.7	-0.7	-0.3	0.3
Impedance of arm (left)	0.3	1.4	9.9	0.1	0.4	0.8	-0.7	-0.4	-0.6	1.8	0.4	0.1	1.4	3.1	-0.2	0.7
Trunk predicted mass	0.3	1.7	15.3	-0.4	0.3	1.1	1.5	0.9	0.8	0.7	0.4	1.1	3.9	0.4	0.2	0.0
Birth weight of first child	0.3	0.5	2.0	0.2	0.2	1.2	0.2	-0.6	-0.5	1.4	-0.6	0.1	1.4	0.0	0.6	-0.3
Loud music exposure frequency	0.3	0.3	1.1	0.7	-0.8	-0.2	-0.2	-0.1	1.0	-0.2	-0.1	0.2	-0.4	-0.2	1.1	0.0
Glaucoma (self-reported)	0.3	0.4	0.9	-0.9	0.5	-0.4	-0.9	0.9	0.7	-0.6	-0.4	-0.5	0.0	-0.5	0.4	-0.8
Gout (self-reported)	0.3	0.4	1.2	0.3	0.5	0.3	0.6	0.7	1.1	-0.5	1.0	0.4	0.3	0.6	0.6	0.2
Medication: Amlodipine	0.3	0.4	1.5	-0.2	-0.1	0.4	1.1	0.1	0.4	-0.0	-0.8	-1.2	0.8	0.0	0.8	0.8
Wheeze or whistling in the chest in last year	0.3	0.5	2.9	-1.7	0.6	-0.4	-0.3	-0.1	-1.0	0.7	0.8	-0.3	0.1	0.7	-0.1	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.2	-0.4	0.2	-0.4	-1.1	0.0	-0.0	0.1	0.7	-0.8	0.0	0.9	0.6	0.3
Age at first live birth	0.3	0.6	1.7	0.3	0.2	0.2	-0.9	-0.8	-1.0	-0.1	0.1	-1.1	1.3	0.7	-1.2	0.8
Mean time to correctly identify matches	0.3	0.6	2.5	1.4	0.4	0.2	-0.4	-0.8	-0.6	0.3	0.8	-0.1	-1.6	-0.0	-0.2	0.7
Arm predicted mass (right)	0.3	1.6	14.5	-1.3	0.6	0.9	1.2	0.5	0.5	-0.1	0.6	0.8	3.8	0.2	0.0	-0.3
Chest pain or discomfort	0.3	0.4	1.8	-0.7	1.3	0.3	0.1	-0.5	-0.4	0.6	-0.6	-0.4	-0.4	0.4	1.2	-0.4
Family relationship satisfaction	0.3	0.4	1.4	1.0	0.1	0.3	0.0	0.5	-0.1	0.9	-1.0	1.2	-0.1	-0.3	0.4	0.6
Back pain experienced in last month	0.3	0.5	1.2	-0.9	-0.3	0.0	0.7	-1.1	-0.4	0.5	-1.1	-0.3	-0.7	-0.3	0.8	-0.9
Alcohol drinker status: Never	0.3	0.3	0.8	-0.0	0.9	0.8	-0.6	-0.4	-0.6	0.3	0.8	0.0	-0.4	0.0	0.8	0.2
Basal metabolic rate	0.3	1.7	15.4	-1.4	0.7	0.9	1.1	0.4	0.5	0.2	0.6	0.9	3.9	-0.1	0.4	-0.5
Arm fat-free mass (left)	0.3	1.7	15.3	-1.1	0.6	1.0	1.5	0.7	0.8	0.4	0.5	1.1	3.9	0.1	0.2	-0.2
Arm predicted mass (left)	0.3	1.4	13.2	-1.4	0.5	0.6	1.1	0.3	0.2	0.0	0.0	0.6	3.6	0.0	0.0	-0.5
Crohns Disease (2017)	0.2	0.4	1.2	0.3	0.5	-0.5	-0.6	-1.1	-0.3	-0.2	1.1	-0.5	-0.2	-0.2	0.8	0.3
Irritable Bowel Disease (IBD)	0.2	0.6	2.2	0.8	0.8	-0.1	-0.6	-0.9	0.1	-0.4	1.5	-0.1	1.1	0.6	0.7	0.8
Major Depression (MDD)	0.2	0.3	0.9	-0.0	0.0	0.1	-0.5	-0.3	-0.4	0.2	0.7	0.4	0.3	1.0	-0.8	0.6
Ulcerative Colitis	0.2	0.2	1.1	0.5	0.3	-0.0	-0.7	-0.1	0.1	-0.4	-0.6	0.4	1.1	0.4	0.6	0.3
Blood Eosinophil Count	0.2	1.8	8.1	-1.5	2.1	0.4	0.7	0.4	-0.4	1.3	1.0	2.0	2.8	-0.6	0.8	0.6
Blood Platelet Count	0.2	2.2	9.4	-1.0	3.1	-0.4	0.6	-2.5	-2.9	0.3	0.5	0.3	1.0	-0.5	0.6	0.5
Sensitivity / hurt feelings	0.2	0.3	1.6	0.2	1.0	0.0	-0.4	1.3	1.1	0.1	0.2	-0.0	-0.3	-0.1	0.1	0.6
Taking other prescription medications	0.2	0.3	1.8	-0.4	0.5	0.2	-0.7	0.5	0.7	-0.0	-0.1	-0.7	-0.1	1.3	0.1	-0.4
Hearing difficulty/problems with background noise	0.2	0.3	1.4	-1.2	-0.4	-0.1	0.5	0.9	0.5	0.2	-0.4	-0.9	-0.4	0.2	0.4	0.4
Illnesses of mother	0.2	0.2	1.0	0.0	1.0	0.0	-0.3	0.6	-0.2	0.1	0.7	-0.1	0.1	-0.6	0.1	0.4
Arm fat-free mass (right)	0.2	1.0	10.8	-0.9	0.5	0.5	0.9	0.1	0.0	-0.2	0.5	0.5	3.3	-0.0	0.2	-0.2
Comparative body size at age 10	0.2	0.6	2.2	-0.7	1.0	-0.2	-1.0	0.1	1.0	0.2	0.4	0.5	0.2	0.3	1.5	-0.9
Medication: Allopurinol	0.2	0.2	1.4	-0.1	-0.0	-0.4	-0.2	0.2	0.8	-1.2	-0.5	-0.6	-0.4	0.0	0.0	-0.3
Illnesses of father: Heart disease	0.2	0.3	1.0	0.6	-1.0	0.7	0.1	0.6	-0.2	0.8	-0.7	-0.1	-0.1	0.0	-0.1	0.1
Smoking status: Previous	0.2	0.2	0.8	0.5	0.9	0.4	0.4	-0.5	-0.8	0.3	-0.3	0.1	-0.7	-0.1	0.3	0.1
Whole body fat-free mass	0.2	1.4	13.7	-0.8	0.4	0.8	1.2	0.5	0.5	0.3	0.5	0.8	3.7	-0.1	0.4	-0.3
Leg fat-free mass (right)	0.2	1.3	11.1	-1.2	0.4	0.5	0.7	0.0	0.2	-0.2	0.5	0.8	3.3	-1.1	0.3	-0.8
Average weekly red wine intake	0.2	0.2	0.9	0.7	1.0	0.5	-0.5	-0.4	-0.5	0.6	0.5	0.3	0.3	0.0	-0.2	0.1
Mood swings	0.2	0.3	1.0	-1.0	0.3	-0.5	0.3	0.5	-0.1	-0.1	0.2	0.7	0.7	-0.4	-0.2	-0.9
Osteoarthritis (self-reported)	0.2	0.3	1.2	0.5	-0.2	-0.3	0.1	-0.9	-1.1	-0.5	-0.0	-0.9	-0.7	-0.1	0.2	0.2
Whole body water mass	0.2	1.4	13.7	-1.0	0.4	0.7	1.1	0.5	0.5	0.1	0.3	0.8	3.7	-0.2	0.4	-0.4
Leg predicted mass (right)	0.2	1.3	11.1	-1.2	0.4	0.5	0.7	0.0	0.3	-0.2	0.5	0.8	3.3	-1.0	0.5	-0.7
Medication: Blood pressure	0.2	0.3	1.1	-0.7	-0.1	0.7	0.3	0.3	0.5	-0.3	0.5	-0.7	0.4	1.1	0.9	0.1
Irritability	0.2	0.4	1.0	-0.8	0.5	-0.9	0.4	-0.7	-0.9	-0.4	0.2	-0.2	-1.0	-0.7	-0.1	-0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.5	-0.6	-0.3	0.5	0.3	-0.4	-0.6	-0.2	-0.1	0.4	0.6	0.1	-0.3	-0.7
Neuroticism (Nagel 2018)	0.1	0.2	1.3	-0.7	0.2	-0.4	0.6	0.2	-0.3	-0.1	0.7	0.2	-0.4	-0.1	-1.1	0.2
Breast Cancer	0.1	0.3	1.0	-0.5	-0.3	0.8	-0.0	0.5	0.7	-0.3	0.8	1.0	-0.6	-0.7	-0.2	-0.1
Blood White Count	0.1	0.8	2.0	-1.3	1.1	-0.5	0.4	-0.8	0.1	-0.4	-1.2	-0.7	1.4	-1.2	-0.0	-1.1
Neuroticism	0.1	0.2	0.6	0.1	0.4	-0.7	0.5	0.4	0.0	-0.3	0.2	-0.7	0.1	0.0	-0.8	0.1
Hair Pigment	0.1	1.7	6.4	-1.7	-0.7	-1.4	-2.5	-1.4	-2.1	-0.7	-0.1	0.9	-1.0	-0.1	-1.0	-0.7
Tanning	0.1	1.7	6.2	0.7	-0.9	-1.1	-0.9	-0.3	-0.9	-1.5	-2.5	-0.8	-0.9	-2.5	-0.8	-0.9
Miserableness	0.1	0.2	0.7	-0.1	-0.1	-0.6	0.3	0.4	0.0	-0.3	-0.6	-0.3	-0.4	-0.7	-0.8	-0.9

Hub : Genes

CROCCP2

Models

Trait associations