[Hub]/) : Traits : Schizophrenia (2018) : ← →

chr10:103,313,599-106,042,502

Best TWAS P=9.06e-17 · Best GWAS P=2.68e-15 conditioned to 0.799

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NEURL	0.05	0.00	blup	417	0.02	7.9e-04	4.19	-5.1	2.6e-07	0.37	0.10	0.06	FALSE
2	GTEx	Adipose Subcutaneous	CYP17A1-AS1	0.05	0.02	enet	10	0.03	2.8e-03	-5.47	-6.2	7.7e-10	0.65	0.12	0.67	FALSE
3	GTEx	Artery Aorta	NT5C2	0.08	0.02	lasso	7	0.01	1.2e-01	4.20	6.4	1.2e-10	-0.70	0.11	0.69	FALSE
4	GTEx	Artery Aorta	ARL3	0.19	0.07	lasso	6	0.06	4.8e-04	-5.07	5.7	1.5e-08	-0.37	0.46	0.23	FALSE
5	GTEx	Artery Tibial	NT5C2	0.06	0.04	lasso	9	0.02	1.5e-02	-6.22	6.7	2.2e-11	-0.92	0.03	0.91	FALSE
6	GTEx	Artery Tibial	CYP17A1-AS1	0.08	0.08	lasso	8	0.06	2.8e-05	-6.22	-6.0	1.7e-09	0.89	0.04	0.96	FALSE
7	GTEx	Brain Cortex	CYP17A1-AS1	0.15	0.13	lasso	7	0.14	1.3e-04	-5.08	-5.5	3.6e-08	0.79	0.06	0.83	FALSE
8	GTEx	Breast Mammary Tissue	CYP17A1-AS1	0.10	-0.01	enet	28	0.00	2.4e-01	-3.37	-5.4	7.4e-08	0.67	0.04	0.76	FALSE
9	GTEx	Breast Mammary Tissue (Female)	CYP17A1-AS1	0.14	0.01	lasso	11	0.00	4.7e-01	-6.58	-7.0	2.0e-12	0.64	0.04	0.53	FALSE
10	GTEx	Cells Transformed fibroblasts	GBF1	0.07	0.00	enet	2	0.00	1.4e-01	-5.47	-5.4	5.6e-08	0.32	0.08	0.04	FALSE
11	GTEx	Cells Transformed fibroblasts	SUFU	0.07	0.04	lasso	3	0.04	3.5e-04	-6.44	-5.3	1.2e-07	0.31	0.41	0.10	FALSE
12	GTEx	Cells Transformed fibroblasts	ARL3	0.07	0.00	enet	13	0.04	1.2e-03	-5.51	5.1	3.1e-07	-0.33	0.09	0.54	FALSE
13	GTEx	Colon Sigmoid	ARL3	0.13	0.10	lasso	6	0.05	5.5e-03	-5.07	5.3	1.1e-07	-0.36	0.18	0.27	FALSE
14	GTEx	Esophagus Gastroesophageal Junction	CYP17A1-AS1	0.23	0.08	enet	23	0.13	1.9e-05	-4.89	-5.9	4.8e-09	0.60	0.14	0.42	FALSE
15	GTEx	Liver	ACTR1A	0.15	0.00	lasso	10	0.00	4.6e-01	0.49	5.7	9.1e-09	-0.66	0.03	0.56	FALSE
16	GTEx	Pancreas	CYP17A1-AS1	0.11	0.06	lasso	5	0.06	1.1e-03	-7.77	-6.3	3.1e-10	0.85	0.02	0.86	FALSE
17	GTEx	Testis	NT5C2	0.20	0.03	lasso	8	0.08	2.8e-04	-6.44	-5.3	1.4e-07	0.33	0.12	0.75	FALSE
18	GTEx	Testis	CYP17A1-AS1	0.14	0.08	enet	5	0.10	2.3e-05	-6.76	6.7	2.7e-11	-0.45	0.14	0.82	FALSE
19	GTEx	Thyroid	WBP1L	0.26	0.10	enet	9	0.13	2.1e-10	-3.46	5.6	1.6e-08	-0.30	0.81	0.19	FALSE
20	METSIM	Adipose	AS3MT	0.24	0.28	lasso	12	0.28	6.1e-43	-4.26	5.4	5.1e-08	-0.90	0.80	0.20	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	ARL3	0.24	0.14	bslmm	368	0.16	3.9e-20	-5.07	5.9	3.7e-09	-0.43	1.00	0.00	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	CNNM2	0.11	0.08	lasso	3	0.07	2.2e-09	-7.15	-7.1	9.9e-13	0.44	0.06	0.94	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	CYP17A1-AS1	0.15	0.18	lasso	6	0.19	1.3e-23	-5.08	-5.7	9.0e-09	0.77	1.00	0.00	FALSE
24	YFS	Blood	ARL3	0.39	0.14	enet	30	0.20	7.0e-63	-5.07	-5.4	8.5e-08	0.50	1.00	0.00	FALSE
25	YFS	Blood	NT5C2	0.13	0.10	bslmm	382	0.11	7.3e-35	-7.47	-5.8	5.5e-09	0.25	0.04	0.96	FALSE
26	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	AS3MT	0.06	0.09	enet	6	0.07	1.3e-06	-7.77	8.3	9.1e-17	-0.94	0.00	1.00	TRUE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	AS3MT	0.05	0.05	enet	10	0.05	4.7e-11	-7.77	7.0	2.0e-12	-0.94	0.00	1.00	FALSE
28	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C10orf32	0.16	0.06	blup	54	0.10	1.3e-05	-3.93	5.3	1.1e-07	-0.86	0.02	0.97	FALSE
29	The Cancer Genome Atlas	Glioblastoma Multiforme	AS3MT	0.15	0.05	blup	62	0.10	5.1e-04	-3.93	5.9	4.7e-09	-0.87	0.01	0.86	FALSE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AS3MT	0.05	0.05	blup	62	0.06	1.1e-07	-6.04	5.6	1.7e-08	-0.89	0.01	0.99	FALSE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ARL3	0.03	0.02	lasso	3	0.02	1.1e-03	-5.29	5.3	1.4e-07	-0.32	0.01	0.85	FALSE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AS3MT	0.04	0.05	enet	3	0.04	8.6e-06	-7.77	7.8	5.9e-15	-1.00	0.00	1.00	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	AS3MT	0.34	0.38	lasso	6	0.38	4.4e-46	-3.93	5.6	1.7e-08	-0.92	0.23	0.77	FALSE
34	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	AS3MT	0.13	0.14	blup	62	0.13	5.6e-06	-6.22	6.4	1.9e-10	-0.93	0.02	0.98	FALSE
35	The Cancer Genome Atlas	Prostate Adenocarcinoma	AS3MT	0.16	0.21	lasso	9	0.24	2.5e-24	-7.91	6.0	2.4e-09	-0.93	0.00	1.00	FALSE
36	The Cancer Genome Atlas	Rectum Adenocarcinoma	C10orf32	0.17	0.14	blup	52	0.14	3.2e-04	-6.22	6.6	4.1e-11	-0.94	0.01	0.85	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	ARL3	0.06	0.07	lasso	4	0.06	3.5e-06	-5.07	5.1	2.8e-07	-0.33	0.03	0.97	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	AS3MT	0.23	0.18	lasso	3	0.18	1.8e-17	-7.91	7.4	1.1e-13	-1.00	0.00	1.00	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	C10orf26	0.06	0.05	lasso	5	0.04	4.1e-05	-4.89	5.5	3.4e-08	-0.68	0.17	0.72	FALSE
40	The Cancer Genome Atlas	Thyroid Carcinoma	CYP17A1	0.04	0.02	lasso	1	0.02	3.9e-03	-6.04	6.0	1.6e-09	-0.85	0.03	0.71	FALSE