TWAS hub - C10orf26

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0575	0.0211	1.1e-06	0.031	0.019	0.021	0.021	0.028	2.7e-10	5.2e-07	1.9e-07	1.7e-07	2.0e-09
2	TCGA	Breast Invasive Carcinoma	0.0257	0.0120	6.1e-04	0.021	0.016	0.017	NA	0.017	2.9e-05	2.8e-04	1.6e-04	NA	1.8e-04
3	TCGA	Thyroid Carcinoma	0.0600	0.0280	3.9e-05	0.046	0.042	0.038	NA	0.044	2.8e-05	5.5e-05	1.3e-04	NA	4.1e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Worrier / anxious feelings	12.3	23.2	37.9	-2.3	5.1	6.2
Birth weight	11.5	25.0	56.6	7.5	-1.4	-4.0
Systolic Blood Pressure	10.4	51.8	110.2	-6.6	1.2	10.5
Worry (Nagel 2018)	9.2	19.4	30.0	-3.7	3.8	5.5
Schizophrenia (2014)	9.1	20.2	36.9	-3.9	3.0	6.1
Smoking Status	8.9	21.2	27.9	3.4	-5.3	-4.9
Schizophrenia (2018)	8.6	17.8	30.5	-4.3	2.1	5.5
Systolic blood pressure, automated reading	8.5	24.7	46.9	-4.9	1.7	6.8
Bipolar Disorder or Schizophrenia	7.7	18.9	36.8	-3.5	2.8	6.1
Hand grip strength (left)	7.5	19.8	28.8	1.8	-5.4	-5.2
Migraine (self-reported)	7.3	9.1	15.3	3.5	0.3	-3.9
Past tobacco smoking	6.8	12.4	24.9	-1.3	5.0	3.2
Nervous feelings	6.6	12.3	17.8	-3.8	2.3	4.2
Type 2 Diabetes (T2D) (2018)	6.1	11.5	19.9	-1.9	-4.5	-3.3
Hand grip strength (right)	6.0	16.3	25.3	1.1	-4.7	-5.0
Birth weight of first child	5.9	10.7	15.4	3.9	-1.7	-3.7
Coronary Artery Disease (CAD)	5.8	6.9	14.2	-2.0	1.6	3.8
Pulse wave peak to peak time	5.7	6.8	9.4	1.6	-2.9	-3.1
Forced expiratory volume in 1-second (FEV1), predicted	5.7	11.8	24.0	1.2	-4.9	-3.2
Ever smoked	5.7	9.9	15.1	1.3	-3.9	-3.6
Allergy or Eczema	5.6	14.7	42.1	1.0	6.5	0.8
Height	5.5	106.9	256.0	2.8	-16.0	-7.5
Diabetes (self-reported)	5.4	8.3	13.4	-1.5	-3.7	-3.0
Number of incorrect matches in round	5.1	8.4	13.8	-1.5	3.0	3.7
Trunk fat-free mass	5.1	29.5	42.4	2.9	-6.5	-6.2
Trunk predicted mass	5.1	29.1	40.6	3.0	-6.4	-6.2
Type 2 Diabetes (T2D) (2012)	5.0	5.8	9.6	-2.8	0.0	3.1
Whole body fat-free mass	5.0	28.6	44.2	2.8	-5.8	-6.7
Smoking status: Current	5.0	7.9	10.6	1.6	-3.3	-3.2
Arm fat-free mass (left)	5.0	25.2	39.1	2.3	-5.6	-6.2
Arm predicted mass (left)	5.0	25.3	39.4	2.0	-5.7	-6.3
Neuroticism	4.9	11.7	16.7	-2.5	3.5	4.1
Whole body water mass	4.9	28.1	44.1	2.7	-5.8	-6.6
Arm fat-free mass (right)	4.8	24.7	34.6	2.4	-5.8	-5.9
Arm predicted mass (right)	4.8	24.6	34.3	2.3	-5.8	-5.9
Basal metabolic rate	4.8	26.7	43.7	2.3	-5.6	-6.6
Peak expiratory flow (PEF)	4.7	10.8	16.9	1.0	-3.8	-4.1
Diabetes diagnosed by doctor	4.7	7.8	11.0	-1.5	-3.3	-3.2
Leg fat-free mass (left)	4.6	24.1	46.6	2.2	-4.6	-6.8
Current tobacco smoking	4.6	7.6	11.4	1.3	-3.4	-3.1
Hayfever, allergic rhinitis or eczema	4.6	10.1	28.0	0.9	5.3	1.1
Leg fat-free mass (right)	4.6	24.8	46.0	2.7	-4.6	-6.8
Leg predicted mass (right)	4.6	24.5	45.5	2.7	-4.5	-6.7
Schizophrenia vs Biploar Disorder	4.5	5.9	8.1	-2.8	2.1	2.3
Leg predicted mass (left)	4.5	23.7	45.7	2.2	-4.5	-6.8
Standing height	4.5	44.4	100.0	2.6	-10.0	-5.2
Pulse wave reflection index	4.5	5.6	8.6	2.9	-1.7	-2.3
Neuroticism (Nagel 2018)	4.4	10.3	18.1	-2.8	2.2	4.3
Chronotype (morning person)	4.4	10.1	26.8	5.2	1.3	-1.4
Prostate Cancer	4.3	6.0	15.4	-0.3	3.9	1.6
Medication: Metformin	4.2	6.0	12.9	-0.6	-2.2	-3.6
Pulse wave Arterial Stiffness index	4.1	4.8	7.4	-1.5	2.2	2.7
Exposure to tobacco smoke outside home	4.1	5.5	8.6	0.2	-2.9	-2.8
Weight	4.0	19.7	38.9	1.1	-4.4	-6.2
Worry too long after embarrassment	3.9	6.5	12.7	-3.6	1.5	2.2
Maternal smoking around birth	3.7	5.4	9.5	0.8	-2.4	-3.1
High blood pressure (mother)	3.7	5.2	11.1	-1.2	1.7	3.3
Length of working week for main job	3.7	4.1	8.4	-1.9	-2.9	-0.7
Suffer from ‘nerves’	3.7	5.8	10.0	-1.8	2.0	3.2
Major Depression (MDD)	3.6	4.4	11.1	-1.4	0.3	3.3
Seen a psychiatrist for nerves, anxiety, tension or depression	3.6	4.6	11.4	-0.3	1.5	3.4
Severe depression (siblings)	3.5	3.9	7.6	-1.4	1.5	2.8
Medication: Ramipril	3.5	4.5	10.9	-1.6	0.1	3.3
Medication: Paracetamol	3.5	5.9	10.7	-2.5	0.7	3.3
Heart disease (mother)	3.5	4.3	10.2	-1.6	0.6	3.2
Comparative height size at age 10	3.5	19.5	45.4	1.4	-6.7	-3.3
Reaction Time	3.4	6.4	12.8	-0.5	3.6	2.5
Bilateral oophorectomy (both ovaries removed)	3.4	4.0	7.7	1.3	2.8	1.6
Allergy	3.4	7.9	21.3	0.2	-4.6	-1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	3.4	5.2	11.2	-2.0	-0.5	3.3
Fractured/broken bones in last 5 years	3.4	4.4	5.2	-2.2	1.8	2.3
Pulse rate	3.3	5.6	8.0	-1.9	2.8	2.3
Commuting to job workplace: Walk	3.3	3.5	5.6	-0.5	2.4	2.2
Bipolar Disorder (2011)	3.1	3.0	6.3	0.1	1.6	2.5
Neuroticism score	3.1	6.5	9.3	-1.2	3.0	3.1
Commuting to job workplace: Car/motor vehicle	3.1	3.6	7.4	2.7	-0.4	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	3.1	3.3	6.8	-2.6	-1.7	0.6
Sitting height	2.9	20.6	54.3	1.6	-7.4	-2.2
Illnesses of father: None of the above (group 1)	2.9	3.6	7.0	1.7	0.9	-2.6
Cardiovascular Disease	2.8	9.2	21.6	-1.9	-1.6	4.7
Hip circumference	2.8	12.1	30.8	1.1	-2.1	-5.6
Reason for reducing amount of alcohol drunk: Health precaution	2.8	3.3	6.8	-0.8	-2.6	1.6
Medication: Lisinopril	2.8	3.7	6.4	-1.7	-1.3	2.5
Body Mass Index (BMI) (2010)	2.7	3.7	11.1	-0.1	0.0	-3.3
Eye problems/disorders: Diabetes related eye disease	2.7	3.0	4.7	0.2	-2.2	-2.1
Hearing difficulty/problems with background noise	2.7	4.3	11.7	0.6	-3.4	-0.8
Leg fat mass (left)	2.7	10.6	25.9	0.3	-2.4	-5.1
Waist Hip Ratio (WHR)	2.6	11.6	25.5	-3.0	-5.0	0.8
Waist circumference	2.6	9.5	16.7	-0.8	-3.4	-4.1
Leg fat mass (right)	2.6	10.3	25.0	0.1	-2.4	-5.0
Medication: Paracetamol	2.6	4.0	8.0	-1.9	0.6	2.8
BMI	2.5	14.4	42.6	0.4	-0.6	-6.5
Smoking status: Previous	2.5	3.8	9.7	0.8	-3.1	-1.0
Bipolar Disorder (2018)	2.4	3.8	7.9	-0.2	1.9	2.8
Lupus	2.4	3.7	7.3	2.7	0.0	-1.9
High blood pressure	2.4	6.8	16.2	-1.8	-1.0	4.0
Ever depressed for a whole week	2.4	2.9	3.8	-1.9	-1.4	1.7
Ulcerative Colitis (UC)	2.3	4.2	11.6	3.4	-0.9	-0.6
Trunk fat mass	2.3	10.1	23.4	-0.3	-2.6	-4.8
Whole body fat mass	2.3	9.8	23.9	-0.3	-2.3	-4.9
Hypertension (Self-reported)	2.3	6.5	16.0	-1.7	-0.7	4.0
Pain type(s) experienced in last month: Hip pain	2.2	2.8	6.3	-0.7	2.5	1.2
Medication: Bendroflumethiazide	2.2	3.3	5.6	-1.3	-1.6	2.4
Vascular/heart problems diagnosed by doctor	2.2	6.0	13.6	1.8	1.0	-3.7
Sensitivity / hurt feelings	2.1	3.6	6.1	-2.5	0.6	2.1
Diabetes (mother)	2.1	2.7	5.9	-1.3	-2.4	-0.9
Impedance of leg (right)	2.1	10.2	21.7	-3.0	-0.4	4.7
Ever taken oral contraceptive pill	2.1	2.4	6.0	-0.1	-1.0	-2.5
Supplements: Zinc	2.0	2.2	4.7	0.5	-2.2	-1.3
Had menopause	2.0	2.4	5.2	0.3	2.3	1.4
Forced vital capacity (FVC)	2.0	7.6	15.1	1.0	-3.9	-2.6
Medication for pain relief, constipation, heartburn	2.0	3.4	5.2	2.2	-0.5	-2.3
Number of self-reported non-cancer illnesses	2.0	3.5	8.8	0.5	1.3	3.0
Serious illness, injury or assault to yourself	1.9	2.2	4.5	-2.1	0.3	1.5
Medication: Lansoprazole	1.9	2.2	4.8	-0.6	1.2	2.2
Chronic bronchitis/emphysema (father)	1.8	2.1	4.6	-2.1	0.7	1.1
Arm fat mass (right)	1.8	7.4	20.4	-0.0	-1.3	-4.5
Ever highly irritable/argumentative for 2 days	1.8	2.1	5.7	-0.1	-0.8	2.4
Headache pain in last month	1.8	3.0	5.3	2.3	1.9	0.5
Arm fat mass (left)	1.8	7.5	20.6	0.0	-1.4	-4.5
Financial situation satisfaction	1.8	2.2	4.4	0.9	-2.1	-1.2
Ever used hormone-replacement therapy (HRT)	1.7	2.1	4.4	0.0	1.4	2.1
Vitamin and mineral supplements	1.7	2.4	6.4	-0.5	0.6	2.5
Number of live births	1.7	2.4	3.6	-1.9	0.9	1.6
Forced expiratory volume in 1-second (FEV1)	1.7	5.8	10.1	0.3	-3.2	-2.7
Pulse rate, automated reading	1.7	5.4	7.4	-2.0	2.7	2.2
Ever had bowel cancer screening	1.7	2.0	3.5	1.6	-1.9	0.2
Medication for cholesterol	1.7	2.6	6.9	0.7	0.6	-2.6
Medication: Gliclazide	1.7	1.9	3.1	-0.8	-1.8	-1.4
Illnesses of father: High blood pressure	1.7	2.1	5.4	-0.9	-0.2	2.3
Diastolic blood pressure, automated reading	1.7	5.1	7.8	-0.5	-2.7	2.8
Impedance of whole body	1.7	8.7	19.7	-2.3	1.0	4.4
Blood White Count	1.6	11.8	30.8	-2.1	-5.5	-0.4
Impedance of leg (left)	1.6	7.9	18.7	-2.2	-0.5	4.3
Blood clot in the leg (DVT)	1.6	2.0	4.2	-2.1	0.3	1.3
High blood pressure (siblings)	1.6	2.3	6.7	0.2	-0.5	2.6
Mean time to correctly identify matches	1.6	3.0	4.7	-0.4	2.2	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	5.3	0.6	-2.3	0.1
Average weekly champagne plus white wine intake	1.6	2.2	3.3	1.8	-0.1	-1.8
Crohns Disease (2012)	1.5	2.3	4.1	-0.9	-2.0	-1.5
Neuroticism (2016)	1.5	2.2	4.4	-0.0	1.5	2.1
Ulcerative Colitis	1.5	2.2	3.1	1.7	-1.8	-0.7
Number of treatments/medications taken	1.5	2.6	7.0	-0.9	-0.3	2.6
Ever had hysterectomy (womb removed)	1.5	1.6	3.1	1.3	1.8	0.5
Townsend deprivation index at recruitment	1.5	2.1	3.0	0.8	-1.6	-1.7
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	4.9	0.0	2.2	1.0
Mouth/teeth dental problems: Bleeding gums	1.5	2.0	4.8	2.2	-0.0	-1.1
Forced vital capacity (FVC), Best measure	1.5	5.5	8.7	1.6	-2.9	-2.3
Comparative body size at age 10	1.5	4.0	7.6	-2.0	-0.7	-2.8
Illnesses of siblings: Diabetes	1.5	1.8	4.5	-0.4	-2.1	-0.8
Qualifications: nursing, teaching	1.5	2.3	4.8	-2.2	-1.2	0.8
Commuting to job workplace: Public transport	1.5	1.8	4.9	-2.2	-0.0	0.8
Medication: Blood pressure	1.5	2.8	5.0	-1.4	-1.2	2.2
Average weekly spirits intake	1.4	1.7	5.0	-2.2	0.0	-0.3
Medication: Co-codamol	1.4	1.6	2.5	-1.2	1.0	1.6
Body mass index (BMI)	1.4	5.9	17.8	0.0	0.0	-4.2
Impedance of arm (left)	1.4	6.5	13.0	-1.8	1.9	3.6
Eye problems/disorders: None of the above	1.4	1.6	2.0	1.0	1.3	-1.4
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	3.0	-1.7	0.4	1.5
Depression (Nagel 2018)	1.3	1.9	3.6	0.4	1.9	1.4
Verbal and Numeric Reasoning (VNR)	1.3	3.1	4.5	2.1	-0.9	-2.0
Hearing difficulty/problems: Yes	1.3	2.0	4.6	1.2	-2.1	0.1
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	3.1	0.4	1.8	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.2	6.1	1.2	-2.3	-2.5
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	2.6	0.2	1.6	-1.5
Age at First Birth	1.2	1.7	3.4	1.9	-0.4	-1.3
Rheumatoid Arthritis	1.2	1.6	2.5	0.3	-1.5	-1.6
Blood Platelet Count	1.2	13.9	39.4	-0.2	-6.3	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.9	6.1	-1.6	-2.5	-0.1
Fluid intelligence score	1.2	2.5	3.6	1.4	-1.3	-1.9
Arm fat percentage (right)	1.2	4.6	13.1	-0.9	0.2	-3.6
Mouth/teeth dental problems: Dentures	1.2	2.0	4.0	1.1	-1.0	-2.0
Medication: Ventolin 100micrograms inhaler	1.2	1.6	3.5	-1.9	0.2	1.1
Mouth/teeth dental problems: Loose teeth	1.2	1.5	3.2	0.2	-1.1	-1.8
Medication: Blood pressure	1.2	2.1	5.5	-0.6	-0.6	2.3
Ever had prostate specific antigen (PSA) test	1.2	1.4	1.9	1.3	1.4	0.6
HbA1C	1.1	1.2	1.9	-0.2	1.4	1.3
Blood Red Count	1.1	10.4	17.0	3.7	0.8	4.1
Taking other prescription medications	1.1	1.6	4.6	0.1	0.6	2.1
Pain all over the body in last month	1.1	1.1	2.4	0.3	1.5	1.0
Impedance of arm (right)	1.1	5.2	9.4	-2.0	1.5	3.1
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	2.9	-1.2	1.7	0.0
Medication: Amlodipine	1.1	1.5	2.6	-0.8	1.1	1.6
Body fat percentage	1.1	4.2	10.6	-1.3	-0.5	-3.2
Leg fat percentage (right)	1.1	3.9	9.8	-1.2	-0.6	-3.1
Qualifications: College or University degree	1.1	3.4	6.9	-2.6	0.9	1.6
Mood swings	1.1	2.0	3.3	0.3	1.8	1.6
Mineral and other dietary supplements	1.1	1.5	3.6	-0.9	0.2	1.9
Leg fat percentage (left)	1.1	3.9	10.8	-0.7	-0.6	-3.3
Irritability	1.1	1.8	4.1	2.0	-0.7	-1.0
Pack years adult smoking proportion	1.0	1.6	2.6	-1.1	-1.6	-0.9
Trunk fat percentage	1.0	4.1	10.2	-1.3	-0.7	-3.2
Financial difficulties in last 2 years	1.0	1.4	4.0	-0.3	-2.0	-0.1
Illnesses of father: Heart disease	1.0	1.4	1.8	-0.9	-1.3	1.2
Arm fat percentage (left)	1.0	4.0	11.2	-0.8	0.5	-3.4
Breast cancer (self-reported)	1.0	1.2	3.4	1.8	-0.2	-0.4
Intelligence (Savage-Jansen 2018)	0.9	2.8	5.5	2.4	-1.5	-0.7
Ovarian Cancer	0.9	1.2	2.4	-1.6	-1.1	0.1
Mean Putamen Volume	0.9	1.0	2.7	0.1	-0.6	-1.6
HDL Cholesterol	0.9	1.5	3.0	-1.7	1.2	0.5
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	3.4	0.2	0.4	1.8
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	3.0	-1.7	-1.7	-0.4
Multivitamins +/- minerals	0.9	1.1	3.1	0.4	0.3	-1.8
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	2.8	-0.0	1.7	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	2.2	0.6	-1.5	-1.4
Prospective memory result	0.9	1.1	2.3	-1.5	-0.6	0.7
Asthma (self-reported)	0.9	1.8	3.9	-0.5	2.0	1.1
Unable to work because of sickness or disability	0.9	1.2	2.8	1.7	-0.8	0.1
Pack years of smoking	0.9	1.3	2.4	-0.9	-1.5	-0.9
Depressed Affect (Nagel 2018)	0.8	1.6	2.5	-0.1	1.5	1.6
Irritable Bowel Disease (IBD)	0.8	2.0	3.1	1.8	-1.7	-0.3
Respiratory disease	0.8	1.8	3.7	-0.1	1.9	1.2
Medication for hormone replacement therapy	0.8	0.9	1.2	0.9	0.7	1.1
Average weekly fortified wine intake	0.8	1.0	1.6	-1.3	0.0	1.1
Medication: Atenolol	0.8	1.0	2.2	-0.9	-1.5	-0.1
Medication: Levothyroxine sodium	0.8	1.4	1.6	0.9	1.3	1.3
Medication: Simvastatin	0.8	1.2	2.4	-0.7	-1.6	-0.9
Health satisfaction	0.8	1.0	2.3	-1.5	-0.6	0.6
Age at last live birth	0.8	1.2	2.6	0.3	-0.9	-1.6
Leg pain on walking	0.8	1.0	2.7	-0.2	0.6	1.6
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.1	-0.8	-1.4	-0.4
Supplements: Vitamin C	0.8	1.0	1.8	0.6	-0.9	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	1.5	1.1	-1.2	1.1
Wears glasses or contact lenses	0.8	0.9	2.1	-0.7	-0.2	1.5
Eye problems/disorders: Glaucoma	0.8	1.0	2.8	-1.7	-0.3	0.3
Cholesterol lowering medication	0.8	1.2	2.8	-1.7	-0.7	0.6
Pain experienced in last month	0.8	1.4	2.6	-0.4	-1.6	-1.2
Breast Cancer	0.7	1.8	3.7	-0.9	1.9	0.9
Fasting Glucose	0.7	0.8	1.2	0.0	-1.1	-1.1
Blood Eosinophil Count	0.7	5.5	7.3	-2.7	-2.5	1.7
Qualifications: CSEs or equivalent	0.7	1.0	2.4	1.5	-0.7	-0.1
Mouth/teeth dental problems	0.7	1.1	1.9	-1.4	1.0	0.5
Heart attack	0.7	0.9	1.5	-1.2	0.3	1.0
Illnesses of siblings	0.7	1.0	1.5	-0.3	1.1	-1.2
Alcohol intake versus 10 years previously	0.7	1.0	2.1	0.6	-0.8	-1.4
Father’s age at death	0.7	0.9	1.4	-0.9	-1.2	-0.7
Happiness	0.7	0.9	1.2	-1.0	1.1	0.6
Qualifications: A levels/AS levels or equivalent	0.7	1.5	3.1	-1.2	-1.7	0.2
Asthma	0.7	1.4	3.1	-0.4	1.8	1.0
Lung cancer (father)	0.7	0.8	1.8	1.4	0.0	-0.8
Breastfed as a baby	0.7	0.9	1.4	-0.3	1.1	1.2
Hair/balding pattern: Pattern 4	0.7	1.6	2.4	1.1	1.1	-1.5
Loud music exposure frequency	0.7	0.8	1.4	1.2	-0.5	-0.8
Age at first live birth	0.7	1.2	2.4	0.9	-0.4	-1.6
Neck or shoulder pain in last month	0.7	1.0	1.8	-1.3	0.4	1.1
Medication: Allopurinol	0.7	0.9	1.8	-0.5	-1.3	0.8
Alcohol intake frequency.	0.7	1.6	2.9	0.2	-1.4	-1.7
Medication: Aspirin	0.7	0.9	2.5	-0.2	-1.6	0.3
Knee pain experienced in last month	0.7	1.1	2.5	0.9	0.2	-1.6
Average weekly red wine intake	0.7	1.1	1.9	-1.1	0.1	1.4
Osteoarthritis (self-reported)	0.7	0.9	1.5	0.4	1.1	1.2
Medication: Aspirin	0.7	0.9	2.5	-0.3	-1.6	0.5
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.0	-0.2	-1.4	-0.5
Supplements: Calcium	0.7	0.7	2.0	0.3	-0.3	-1.4
Heart disease (siblings)	0.7	0.9	2.3	0.5	-1.5	0.4
Crohns Disease (2017)	0.6	1.4	3.8	-0.2	-1.9	-0.6
Primary Biliary Cirrhosis	0.6	0.9	1.5	-1.2	-1.1	-0.0
Diabetes (father)	0.6	0.7	1.3	-0.9	-1.1	-0.3
Age when periods started (menarche)	0.6	1.5	3.8	0.2	-0.8	-2.0
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.0	0.8	1.0	0.5
Supplements: Glucosamine	0.6	0.8	2.0	1.4	0.5	-0.5
Alcohol usually taken with meals	0.6	1.0	1.5	-1.1	1.2	0.4
Tense / ‘highly strung’	0.6	0.9	1.5	-0.6	1.2	0.9
Gout (self-reported)	0.6	0.9	1.5	0.1	-1.2	1.1
Angina (self-reported)	0.6	0.8	1.2	-0.7	-0.8	1.1
Medication: Ibuprofen	0.6	0.7	1.3	-1.2	0.8	-0.2
Chest pain or discomfort	0.6	0.9	2.3	1.5	-0.1	0.5
Had major operations	0.6	0.7	1.9	-0.1	0.2	-1.4
Eye problems/disorders: Cataract	0.6	0.7	1.1	-1.0	-1.0	0.2
Mother’s age at death	0.6	0.8	2.1	0.5	-0.3	-1.4
Risk taking	0.6	0.8	1.5	0.9	-0.2	-1.2
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.4	-1.2	0.3	0.9
Alzheimer’s Disease (in father)	0.5	0.6	1.1	0.7	-0.3	1.0
Tanning	0.5	6.7	12.0	0.1	-2.8	-3.5
Angina	0.5	0.7	1.6	-0.3	-1.3	0.6
Hair/balding pattern: Pattern 3	0.5	0.8	0.9	0.7	-1.0	0.9
Glaucoma (self-reported)	0.5	0.6	1.6	-1.3	-0.4	0.4
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.0	0.8	-1.0	-0.1
Medication: Seretide 50 evohaler	0.5	0.6	1.2	0.1	-1.1	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.5	-0.3	-1.2	-0.3
Long-standing illness, disability or infirmity	0.5	0.8	2.0	0.3	-1.4	-0.5
Osteoporosis (self-reported)	0.5	0.7	1.3	-0.8	-0.0	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.9	0.2	0.2	-1.7
High cholesterol (Self-reported)	0.5	0.8	1.4	-0.9	-1.2	-0.6
LDL Cholesterol	0.4	0.6	1.2	0.6	1.1	0.4
Triglycerides	0.4	0.7	1.1	1.0	-0.4	1.0
Lung FEV1/FVC ratio	0.4	2.3	6.5	0.1	-0.5	-2.5
Lung FVC	0.4	1.9	5.7	0.1	2.4	0.2
Fed-up feelings	0.4	0.7	1.6	-0.4	1.3	0.6
Relative age voice broke	0.4	0.6	1.3	-1.2	-0.3	0.7
Had other major operations	0.4	0.5	0.8	0.4	0.7	0.9
Time employed in main current job	0.4	0.4	1.2	1.1	-0.2	-0.1
Illnesses of mother	0.4	0.5	1.5	0.2	-0.3	-1.2
Exposure to tobacco smoke at home	0.4	0.4	1.3	-1.1	0.0	-0.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.2	0.5	0.8	-1.1
Hypothyroidism/myxoedema (self-reported)	0.4	0.9	2.4	0.5	0.1	1.5
Shortness of breath walking on level ground	0.4	0.4	1.0	-0.0	0.6	1.0
Overall health rating	0.4	0.8	2.2	1.5	0.5	-0.0
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.9	-0.5	-1.0	-0.6
Miserableness	0.4	0.8	1.2	0.9	-1.1	-0.5
Hearing aid user	0.4	0.5	0.9	0.3	1.0	0.7
Average weekly beer plus cider intake	0.4	0.5	0.8	0.6	-0.7	0.9
Commuting to job workplace: Cycle	0.4	0.5	0.7	-0.8	-0.8	0.4
Alcohol drinker status: Previous	0.4	0.5	1.3	0.2	0.0	1.1
Heel T-Score	0.3	2.2	3.9	-0.1	-2.0	-1.7
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.9	0.6	0.9	0.4
Relative age of first facial hair	0.3	0.7	1.7	-1.3	-0.5	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.6	0.3	-0.8	0.7
Medication: Omeprazole	0.3	0.4	1.0	-0.3	0.1	1.0
Number of full sisters	0.3	0.4	0.5	-0.6	-0.7	-0.6
Family relationship satisfaction	0.3	0.3	0.6	-0.7	-0.8	0.0
Loneliness, isolation	0.3	0.4	0.9	0.4	1.0	0.2
Friendships satisfaction	0.3	0.3	0.7	-0.5	0.8	0.0
Alcohol drinker status: Never	0.3	0.4	0.6	0.8	0.4	-0.6
Age started oral contraceptive pill	0.3	0.4	0.6	0.2	0.7	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.7	0.0	0.9	0.7
Alzheimer’s Disease (in mother)	0.2	0.3	0.4	0.5	0.4	-0.6
Hypothyroidism (self reported)	0.2	0.3	0.8	0.2	-0.9	0.5
Hair Pigment	0.2	5.5	12.2	-3.5	0.9	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.5	0.7	-0.0	-0.4
Hair/balding pattern: Pattern 2	0.2	0.3	0.8	-0.2	-0.1	-0.9
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.3	-0.5	-0.3	0.6
Qualifications: None of the above	0.2	0.4	0.8	0.7	0.0	-0.9
Falls in the last year	0.2	0.3	0.4	0.7	0.1	0.6
Depression (self-reported)	0.2	0.3	0.5	0.7	0.2	0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.6	0.8	-0.1	0.6
Number of full brothers	0.2	0.2	0.4	0.5	-0.6	0.2
Number of children fathered	0.2	0.2	0.3	-0.3	-0.4	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.4	0.4	0.1	0.6
Back pain experienced in last month	0.2	0.3	0.5	0.7	-0.6	-0.4
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.5	0.4	0.3	-0.7
Number of operations (self-reported)	0.2	0.3	0.9	-0.1	1.0	-0.0
Alzheimer’s Disease (including proxy)	0.1	0.1	0.3	0.5	0.1	-0.1
Noisy workplace	0.1	0.1	0.3	0.6	0.3	0.0
Medication: Cholesterol lowering	0.1	0.2	0.5	0.2	-0.7	-0.4
Wheeze or whistling in the chest in last year	0.1	0.3	0.7	0.8	-0.0	-0.2
Emphysema/chronic bronchitis	0.1	0.1	0.2	-0.3	-0.5	0.1
Guilty feelings	0.1	0.2	0.4	0.3	0.2	0.6
Medication: Atorvastatin	0.1	0.1	0.2	0.3	0.3	0.5
Basal cell carcinoma (self-reported)	0.1	0.1	0.2	0.2	-0.3	0.5
Stomach or abdominal pain in last month	0.0	0.1	0.1	0.3	-0.1	-0.1
Myopia	0.0	0.0	0.1	-0.0	0.3	-0.2

Hub : Genes

C10orf26

Models

Trait associations