Hub : Genes

NEURL

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.046 0.021 0.0027 -0.002 0.023 0.003 0.021 -0.002 8.4e-01 0.00079 0.13000 0.0012 0.5800
2 TCGA Testicular Germ Cell Tumors 0.192 0.084 0.0016 0.130 0.093 0.083 NA 0.072 2.5e-05 0.00036 0.00071 NA 0.0016

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.2 0.3 0.6 -0.7 0.1
Bipolar Disorder or Schizophrenia 4.5 11.1 19.8 -4.5 1.5
Depressed Affect (Nagel 2018) 0.8 1.8 1.9 -1.4 -1.3
Depression (Nagel 2018) 1.1 1.7 1.9 -1.4 -1.2
Intelligence (Savage-Jansen 2018) 0.3 0.9 1.7 1.3 0.3
Neuroticism (Nagel 2018) 2.5 5.8 11.5 -3.4 -0.5
Schizophrenia (2018) 7.2 15.0 26.5 -5.1 1.8
Schizophrenia vs Biploar Disorder 5.3 7.0 13.3 -3.6 0.8
Worry (Nagel 2018) 3.7 7.9 15.2 -3.9 0.7
Alzheimer’s Disease (in mother) 0.9 1.1 2.1 1.4 -0.2
Alzheimer’s Disease (in father) 1.6 1.7 3.1 1.8 -0.6
Alzheimer’s Disease (including proxy) 2.3 3.3 6.0 2.4 -0.8
Crohns Disease (2017) 0.1 0.2 0.3 0.3 0.6
Irritable Bowel Disease (IBD) 1.0 2.3 4.4 2.1 -0.4
Ulcerative Colitis (UC) 2.2 4.1 7.2 2.7 -1.0
Major Depression (MDD) 0.7 0.8 1.6 -1.3 -0.0
Reaction Time 1.1 2.0 4.1 0.1 2.0
Verbal and Numeric Reasoning (VNR) 0.3 0.7 1.2 1.1 -0.4
Breast Cancer 0.8 1.8 3.3 -1.8 0.5
Ovarian Cancer 0.2 0.3 0.5 0.7 0.2
Prostate Cancer 0.5 0.7 1.1 -0.4 1.1
Age at First Birth 1.2 1.8 1.9 1.3 1.4
Bipolar Disorder (2011) 0.8 0.8 1.1 1.0 -0.8
Body Mass Index (BMI) (2010) 0.2 0.2 0.4 -0.2 0.6
Coronary Artery Disease (CAD) 4.7 5.6 10.1 -3.2 1.0
Crohns Disease (2012) 0.3 0.5 0.8 -0.9 -0.4
Mean Putamen Volume 0.7 0.8 1.5 1.2 0.4
Fasting Glucose 2.2 2.6 4.9 -0.5 2.2
HbA1C 1.3 1.5 2.2 -1.5 0.8
HDL Cholesterol 2.6 4.3 5.5 -2.3 1.8
LDL Cholesterol 0.2 0.2 0.4 -0.6 -0.4
Lupus 0.8 1.3 1.4 1.2 -1.1
Neuroticism (2016) 0.6 0.9 1.4 -1.2 0.6
Primary Biliary Cirrhosis 1.0 1.5 2.8 -1.7 -0.3
Rheumatoid Arthritis 0.3 0.4 0.6 0.8 -0.5
Schizophrenia (2014) 4.5 9.9 19.5 -4.4 0.6
Triglycerides 0.4 0.6 1.1 1.1 -0.3
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.2 0.4 -0.5
Ulcerative Colitis 2.3 3.4 4.5 2.1 -1.5
Blood Eosinophil Count 0.1 0.6 1.1 -1.1 -0.1
Blood Platelet Count 1.1 12.4 18.7 4.3 -2.5
Blood Red Count 0.8 7.3 14.5 3.8 0.3
Blood White Count 0.2 1.7 2.0 1.4 -1.2
Heel T-Score 1.0 8.0 15.7 4.0 0.6
BMI 0.6 3.5 6.5 2.5 -0.7
Height 0.7 14.0 17.1 4.1 -3.3
Waist Hip Ratio (WHR) 0.7 3.2 5.5 -2.4 0.9
Systolic Blood Pressure 0.5 2.7 5.2 -2.3 -0.3
Smoking Status 0.4 0.9 1.5 1.2 -0.6
Allergy or Eczema 1.3 3.3 4.5 1.4 -2.1
Cardiovascular Disease 0.1 0.5 0.9 0.3 -1.0
Hypothyroidism (self reported) 0.2 0.5 1.0 -1.0 -0.0
Respiratory disease 0.6 1.3 2.1 1.5 -0.6
Type 2 Diabetes (T2D) (2018) 1.5 2.7 4.2 -2.0 1.1
Lung FEV1/FVC ratio 0.7 3.3 4.8 2.2 -1.3
Lung FVC 1.3 6.7 13.3 -3.7 -0.2
Neuroticism 2.1 5.1 9.7 -3.1 -0.7
Chronotype (morning person) 0.5 1.3 2.5 1.6 -0.1
Hair Pigment 0.0 0.7 1.5 -1.2 0.2
Tanning 0.1 0.8 1.5 -1.2 0.3
Hand grip strength (left) 1.4 3.8 4.7 1.7 -2.2
Number of treatments/medications taken 0.7 1.2 2.4 -1.5 -0.3
Average weekly spirits intake 2.6 3.2 3.9 -1.6 -2.0
Sensitivity / hurt feelings 1.8 3.2 5.9 -2.4 0.6
Frequency of depressed mood in last 2 weeks 0.8 1.1 1.9 -0.6 -1.4
Hearing difficulty/problems: Yes 1.1 1.7 1.8 1.3 1.3
Relative age of first facial hair 1.3 2.6 4.6 0.8 -2.1
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 0.6 0.5 -0.8
Ever used hormone-replacement therapy (HRT) 0.8 1.0 1.3 0.9 -1.2
Ever had hysterectomy (womb removed) 0.8 0.9 1.8 1.3 -0.3
Systolic blood pressure, automated reading 0.9 2.5 4.8 -2.2 0.5
Eye problems/disorders: Diabetes related eye disease 3.0 3.2 3.7 1.7 -1.9
Angina 1.1 1.4 2.7 -1.6 0.4
Medication for hormone replacement therapy 5.7 6.4 10.8 1.4 -3.3
Vitamin and mineral supplements 0.2 0.3 0.6 0.2 -0.8
Supplements: Zinc 0.1 0.1 0.2 0.2 -0.5
Medication: Co-codamol 2.6 3.0 4.4 -1.3 -2.1
Medication: Metformin 0.3 0.4 0.6 -0.8 0.3
Diabetes (father) 2.2 2.7 4.9 -0.8 -2.2
Diabetes (mother) 0.3 0.4 0.8 0.2 0.9
Severe depression (siblings) 0.1 0.1 0.2 -0.1 -0.5
Pack years adult smoking proportion 2.2 3.3 6.4 -0.5 -2.5
Impedance of leg (right) 0.9 4.3 7.9 -2.8 -0.8
Leg fat-free mass (left) 1.9 10.0 16.7 4.1 -1.8
Trunk fat percentage 0.4 1.8 2.3 1.5 -1.1
Hand grip strength (right) 1.2 3.3 5.0 1.3 -2.2
Townsend deprivation index at recruitment 1.4 1.9 3.7 0.3 -1.9
Current tobacco smoking 0.1 0.2 0.3 -0.6 -0.4
Average weekly fortified wine intake 1.0 1.2 1.8 1.3 0.8
Maternal smoking around birth 1.0 1.4 1.9 1.0 -1.4
Fed-up feelings 1.0 1.9 3.0 -0.9 -1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 1.0 -0.7 -1.0
Relative age voice broke 2.0 3.0 5.7 -0.6 -2.4
Taking other prescription medications 0.2 0.4 0.5 -0.7 0.4
Age when periods started (menarche) 1.3 3.1 3.6 1.9 -1.6
Bilateral oophorectomy (both ovaries removed) 0.9 1.1 1.3 0.9 1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.8 1.3 1.2 0.5
Tinnitus: Yes, but not now, but have in the past 0.1 0.1 0.2 0.4 -0.2
Qualifications: CSEs or equivalent 0.4 0.6 0.7 0.8 0.7
Serious illness, injury or assault to yourself 1.6 1.9 2.5 -1.6 -1.1
High blood pressure 0.1 0.3 0.5 -0.7 -0.2
Hayfever, allergic rhinitis or eczema 1.0 2.1 2.6 1.3 -1.6
Multivitamins +/- minerals 0.4 0.6 1.0 1.0 0.4
Stomach or abdominal pain in last month 0.1 0.2 0.3 -0.5 0.3
Supplements: Glucosamine 0.1 0.1 0.2 -0.4 -0.1
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 1.5 -1.2 -0.2
Medication: Atenolol 0.8 1.0 1.8 -1.4 0.4
Medication: Levothyroxine sodium 0.3 0.5 0.9 -0.4 -0.9
Sitting height 0.7 4.7 7.4 2.7 -1.4
Chronic bronchitis/emphysema (father) 0.8 0.9 1.9 -1.4 -0.0
High blood pressure (mother) 1.6 2.2 3.4 -1.0 1.8
Body mass index (BMI) 0.5 2.3 4.4 2.1 -0.5
Impedance of leg (left) 0.7 3.3 6.4 -2.5 -0.4
Leg predicted mass (left) 1.8 9.6 16.3 4.0 -1.7
Trunk fat mass 0.9 3.8 5.7 2.4 -1.4
Waist circumference 0.4 1.5 2.9 1.7 -0.0
Number of incorrect matches in round 0.4 0.6 1.1 -1.0 0.4
Past tobacco smoking 0.3 0.5 0.8 -0.9 -0.5
Alcohol usually taken with meals 0.7 1.1 1.9 -1.4 0.6
Nervous feelings 2.6 4.8 9.4 -3.1 0.5
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.6 2.2 -1.5 -1.0
Hearing difficulty/problems with background noise 0.5 0.7 1.4 1.2 -0.2
Hair/balding pattern: Pattern 2 0.2 0.3 0.5 0.7 0.3
Had menopause 1.9 2.3 2.5 -1.6 1.4
Had other major operations 1.3 1.6 2.4 -1.0 1.5
Forced vital capacity (FVC) 0.4 1.6 2.4 -0.9 -1.5
Heel bone mineral density (BMD) T-score, automated (right) 1.2 2.8 5.5 2.3 -0.3
Ever unenthusiastic/disinterested for a whole week 2.0 2.5 3.6 1.1 -1.9
Qualifications: None of the above 0.1 0.2 0.3 -0.5 -0.2
Financial difficulties in last 2 years 3.6 4.8 9.7 0.1 -3.1
Mouth/teeth dental problems 4.7 7.2 13.1 -3.6 1.1
Heart attack 1.1 1.4 2.9 -1.7 0.1
Allergy 0.5 1.2 2.5 -0.2 1.6
Pain all over the body in last month 0.0 0.0 0.0 -0.0 -0.1
Diabetes (self-reported) 0.8 1.2 2.2 -1.5 0.3
Hayfever/allergic rhinitis (self-reported) 1.7 2.2 4.0 2.0 -0.7
Medication: Ramipril 2.8 3.6 6.1 -1.1 2.5
Medication: Simvastatin 0.1 0.2 0.4 0.6 0.2
Fluid intelligence score 0.7 1.4 2.0 0.9 -1.4
Illnesses of siblings 0.0 0.0 0.1 0.2 0.0
Neuroticism score 1.1 2.2 4.0 -2.0 -0.7
Weight 1.4 7.1 11.5 3.4 -1.6
Impedance of arm (right) 0.6 2.7 3.0 -1.6 -1.7
Arm fat percentage (right) 0.4 1.6 2.1 1.4 -1.1
Trunk fat-free mass 1.4 7.9 12.6 3.5 -1.8
Hip circumference 1.1 4.8 8.7 3.0 -0.9
Time employed in main current job 0.7 0.8 1.5 1.2 0.2
Alcohol intake versus 10 years previously 0.1 0.1 0.2 0.4 -0.3
Father’s age at death 1.4 1.9 2.4 -1.6 1.2
Worrier / anxious feelings 1.2 2.2 3.6 -1.9 -1.0
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.9 1.6 -0.4 -1.3
Falls in the last year 1.0 1.3 1.3 1.2 -1.1
Hair/balding pattern: Pattern 3 1.5 2.2 4.0 -2.0 0.6
Number of live births 1.1 1.5 2.3 -0.9 1.5
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 2.6 -0.5 -1.6
Pulse rate 0.3 0.5 0.6 -0.8 0.7
Happiness 2.5 3.1 5.0 -2.2 -1.1
Noisy workplace 0.5 0.6 0.6 0.7 0.8
Qualifications: A levels/AS levels or equivalent 0.0 0.1 0.2 -0.4 0.2
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 0.7 -0.3 -0.8
Mouth/teeth dental problems: Dentures 1.8 3.0 5.8 2.4 0.5
Asthma 0.1 0.2 0.5 -0.7 0.1
Medication: Ibuprofen (e.g. Nurofen) 2.0 2.6 2.8 -1.5 -1.7
Medication: Cholesterol lowering 0.2 0.4 0.4 -0.6 0.5
Depression (self-reported) 0.4 0.4 0.6 -0.8 0.5
Medication: Lansoprazole 3.8 4.3 8.5 0.2 -2.9
Prospective memory result 0.5 0.6 0.6 -0.8 0.7
Lung cancer (father) 1.6 1.9 2.1 1.3 1.5
Illnesses of mother 0.4 0.5 0.9 0.2 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.3 4.7 0.1 -2.2
Pulse wave Arterial Stiffness index 0.7 0.8 1.5 -0.1 1.2
Impedance of arm (left) 0.2 0.9 1.1 -0.8 -1.1
Arm fat mass (right) 0.8 3.1 5.0 2.2 -1.1
Trunk predicted mass 1.4 7.9 12.5 3.5 -1.9
Standing height 0.9 9.4 11.8 3.4 -2.6
Length of working week for main job 0.3 0.4 0.6 -0.3 -0.8
Exposure to tobacco smoke at home 0.8 0.9 1.8 0.1 -1.4
Breastfed as a baby 1.2 1.5 1.5 -1.2 1.2
Tense / ‘highly strung’ 1.2 2.0 3.8 -1.9 0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 2.8 4.3 8.2 -0.7 -2.9
Hair/balding pattern: Pattern 4 0.1 0.1 0.1 -0.4 0.4
Birth weight of first child 0.7 1.3 2.7 1.6 0.1
Peak expiratory flow (PEF) 0.6 1.5 2.5 0.7 -1.6
Pulse wave reflection index 6.3 7.8 14.2 3.8 -1.1
Ever highly irritable/argumentative for 2 days 1.8 2.1 4.0 0.5 -2.0
Loud music exposure frequency 0.0 0.0 0.0 0.0 0.1
Qualifications: O levels/GCSEs or equivalent 1.4 2.2 2.3 1.5 -1.4
Mouth/teeth dental problems: Bleeding gums 2.8 3.6 6.5 2.5 -0.9
Blood clot in the leg (DVT) 0.5 0.7 1.3 -0.2 -1.1
Medication: Paracetamol 1.2 2.0 3.9 -0.3 -2.0
Headache pain in last month 2.7 4.7 8.2 1.1 -2.9
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 0.6 0.3 -0.8
Glaucoma (self-reported) 1.6 1.9 2.3 -1.2 1.5
Gout (self-reported) 1.6 2.1 4.1 2.0 -0.4
Hypothyroidism/myxoedema (self-reported) 0.4 0.7 1.1 -1.1 -0.6
Medication: Amlodipine 0.5 0.7 0.8 0.8 -0.9
Medication: Ventolin 100micrograms inhaler 0.9 1.1 2.2 -1.5 -0.1
Birth weight 8.3 18.0 36.0 6.0 0.2
Chronic bronchitis/emphysema (mother) 1.6 1.9 2.4 1.2 -1.6
High blood pressure (siblings) 0.4 0.6 0.7 0.8 0.7
Forced vital capacity (FVC), Best measure 0.7 2.4 4.7 -0.4 -2.2
Body fat percentage 0.3 1.0 1.4 1.2 -0.8
Leg fat percentage (right) 0.0 0.2 0.2 0.5 -0.3
Arm fat-free mass (right) 1.2 6.1 11.6 3.4 -0.7
Exposure to tobacco smoke outside home 1.1 1.5 2.9 -0.3 -1.7
Comparative body size at age 10 0.9 2.4 2.8 -1.4 1.7
Number of full brothers 0.7 0.9 1.8 1.3 -0.1
Worry too long after embarrassment 1.4 2.3 4.6 -2.1 -0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.2 1.5 3.0 -1.7 0.1
Wheeze or whistling in the chest in last year 0.1 0.2 0.3 0.5 0.4
Number of children fathered 0.1 0.1 0.2 0.4 0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.4 0.7 0.8 0.4
Age at first live birth 2.6 4.6 8.2 1.0 2.9
Pulse wave peak to peak time 0.8 0.9 1.8 0.3 -1.4
Health satisfaction 0.0 0.0 0.0 -0.1 -0.1
Shortness of breath walking on level ground 0.2 0.3 0.5 -0.7 0.3
Qualifications: College or University degree 1.1 3.5 6.9 -2.6 -0.3
Eye problems/disorders: None of the above 0.3 0.3 0.5 -0.7 -0.4
Mouth/teeth dental problems: Loose teeth 0.1 0.1 0.1 -0.4 0.2
Emphysema/chronic bronchitis 2.0 2.3 3.1 -1.8 -1.2
Medication for pain relief, constipation, heartburn 1.0 1.7 1.8 1.2 1.4
Neck or shoulder pain in last month 4.3 6.1 6.2 -2.5 -2.5
Medication: Blood pressure 0.1 0.2 0.4 0.7 0.1
Angina (self-reported) 1.6 2.1 4.2 -2.0 0.3
Migraine (self-reported) 3.5 4.4 7.3 2.7 -1.2
Medication: Ibuprofen 1.4 1.7 2.1 -1.1 -1.5
Medication: Allopurinol 0.9 1.2 2.0 0.6 -1.4
Medication: Omeprazole 0.6 0.7 1.2 1.1 0.4
Medication: Seretide 50 evohaler 0.0 0.0 0.0 -0.1 0.1
Mean time to correctly identify matches 2.6 4.9 9.7 -0.2 3.1
Heart disease (mother) 1.9 2.3 4.3 -2.1 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.7 2.0 2.6 1.6 -1.2
Whole body fat mass 0.7 2.8 4.6 2.1 -1.0
Leg fat mass (right) 0.7 2.6 4.1 2.0 -1.1
Arm predicted mass (right) 1.2 6.2 11.4 3.4 -1.0
Pulse rate, automated reading 0.1 0.5 0.8 -0.4 -0.9
Alcohol intake frequency. 0.0 0.1 0.2 -0.4 -0.1
Comparative height size at age 10 0.4 2.0 4.0 2.0 -0.1
Number of full sisters 0.7 0.8 1.3 -0.6 -1.1
Suffer from ‘nerves’ 1.2 1.9 2.3 -1.5 1.2
Overall health rating 0.0 0.1 0.2 -0.4 -0.1
Chest pain or discomfort 0.7 1.1 2.1 0.2 -1.5
Had major operations 0.5 0.5 0.7 0.8 -0.7
Age at last live birth 4.0 5.9 9.9 1.4 3.1
Family relationship satisfaction 0.8 0.9 1.0 -1.0 -0.9
Leg pain on walking 0.1 0.1 0.1 0.0 -0.4
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.1 1.9 0.5 1.4
Commuting to job workplace: Car/motor vehicle 2.2 2.5 5.1 2.3 -0.1
Illness, injury, bereavement, stress in last 2 years 3.2 4.0 7.6 0.6 2.8
Medication: Aspirin 0.3 0.4 0.8 -0.1 0.9
Supplements: Vitamin C 0.2 0.3 0.5 -0.2 0.7
Knee pain experienced in last month 1.0 1.5 1.8 1.3 1.1
Hypertension (Self-reported) 0.1 0.2 0.3 -0.5 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.1 1.2 2.3 -0.4 -1.5
Illnesses of father: Heart disease 0.7 0.9 1.8 -1.4 0.1
Illnesses of siblings: Diabetes 0.5 0.6 1.3 0.1 -1.1
Smoking status: Previous 0.3 0.5 0.9 0.3 1.0
Forced expiratory volume in 1-second (FEV1), predicted 3.0 6.1 9.9 3.1 -1.5
Whole body fat-free mass 1.5 8.7 14.7 3.8 -1.6
Leg fat-free mass (right) 1.9 10.1 17.8 4.2 -1.5
Arm fat percentage (left) 0.5 1.8 3.2 1.8 -0.7
Average weekly red wine intake 0.8 1.2 2.4 0.0 1.5
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.2 0.2 0.4
Mood swings 0.1 0.3 0.5 -0.7 -0.0
Loneliness, isolation 0.7 0.9 1.7 -1.3 -0.4
Long-standing illness, disability or infirmity 0.0 0.0 0.0 -0.1 0.0
Ever had bowel cancer screening 1.3 1.6 1.8 1.3 1.1
Diabetes diagnosed by doctor 0.8 1.3 2.2 -1.5 0.6
Ever had stillbirth, spontaneous miscarriage or termination 2.5 2.7 2.8 -1.7 1.6
Friendships satisfaction 0.3 0.4 0.8 -0.9 0.1
Qualifications: nursing, teaching 2.0 3.1 3.6 -1.6 1.9
Commuting to job workplace: Walk 1.0 1.1 1.9 -0.5 1.4
Eye problems/disorders: Cataract 0.1 0.1 0.1 0.4 -0.1
Mouth/teeth dental problems: Mouth ulcers 1.3 2.0 3.7 1.9 -0.6
Medication for cholesterol 0.6 1.0 1.9 0.0 1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.2 0.5 0.1
Back pain experienced in last month 0.2 0.3 0.5 -0.1 -0.7
Mineral and other dietary supplements 0.1 0.1 0.1 0.4 0.2
Breast cancer (self-reported) 1.5 1.8 3.5 0.2 1.9
Asthma (self-reported) 0.1 0.2 0.4 -0.6 -0.2
Osteoporosis (self-reported) 2.0 2.5 4.2 -0.9 2.1
Osteoarthritis (self-reported) 0.3 0.4 0.6 -0.8 -0.5
Medication: Aspirin 0.5 0.6 0.9 -0.5 0.9
Medication: Gliclazide 3.2 3.6 4.9 -2.2 1.5
Illnesses of father: None of the above (group 1) 0.5 0.6 1.0 -0.4 1.0
Smoking status: Current 0.0 0.1 0.1 0.1 -0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.5 5.3 10.2 -3.2 -0.6
Whole body water mass 1.5 8.4 14.4 3.8 -1.5
Leg predicted mass (right) 1.9 9.9 17.7 4.2 -1.5
Arm fat mass (left) 0.7 3.0 5.2 2.3 -0.9
Number of self-reported non-cancer illnesses 0.4 0.7 0.8 -0.8 -0.9
Average weekly champagne plus white wine intake 0.1 0.1 0.2 0.0 -0.4
Miserableness 1.4 2.4 4.0 -0.9 -2.0
Guilty feelings 0.0 0.1 0.1 0.0 0.3
Wears glasses or contact lenses 1.7 1.9 3.4 -1.9 0.7
Ever taken oral contraceptive pill 0.7 0.8 1.4 -0.5 -1.2
Hearing aid user 0.1 0.1 0.1 0.2 -0.3
Mother’s age at death 0.4 0.5 1.0 -0.0 1.0
Financial situation satisfaction 1.1 1.4 2.1 0.8 -1.4
Tinnitus: Yes, now most or all of the time 0.5 0.6 1.0 1.0 0.5
Commuting to job workplace: Public transport 2.8 3.3 6.1 -2.5 -0.7
Eye problems/disorders: Glaucoma 2.4 2.8 2.9 -1.7 1.7
Medication: Blood pressure 0.3 0.5 1.0 -1.0 -0.1
Pain type(s) experienced in last month: Hip pain 2.8 3.5 6.1 -2.5 0.9
Supplements: Fish oil (including cod liver oil) 0.1 0.1 0.1 -0.3 -0.2
High cholesterol (Self-reported) 0.1 0.1 0.2 0.5 -0.3
Medication: Bendroflumethiazide 0.6 0.9 1.4 0.7 -1.2
Medication: Paracetamol 0.6 1.0 1.8 -0.5 -1.3
Medication: Lisinopril 1.3 1.7 2.9 0.6 -1.7
Medication: Atorvastatin 0.2 0.3 0.5 -0.7 -0.1
Illnesses of father: High blood pressure 2.4 2.9 4.7 1.1 -2.2
Alcohol drinker status: Never 0.4 0.5 0.6 -0.7 0.8
Ever smoked 0.1 0.2 0.2 0.4 -0.4
Basal metabolic rate 1.6 9.0 14.9 3.9 -1.7
Leg fat percentage (left) 0.1 0.5 0.9 0.9 0.1
Arm fat-free mass (left) 1.1 5.4 9.9 3.1 -1.0
Number of operations (self-reported) 0.2 0.3 0.4 0.6 -0.4
Average weekly beer plus cider intake 2.2 3.2 5.1 2.3 -1.1
Irritability 1.8 3.0 5.0 1.0 -2.2
Risk taking 4.0 5.9 6.2 2.4 -2.5
Ever had prostate specific antigen (PSA) test 2.5 2.9 3.1 1.8 1.6
Fractured/broken bones in last 5 years 1.6 2.1 2.8 -1.7 1.2
Age started oral contraceptive pill 0.2 0.2 0.3 0.4 0.6
Diastolic blood pressure, automated reading 1.0 3.1 6.0 2.4 0.5
Ever depressed for a whole week 1.5 1.8 3.7 0.2 -1.9
Unable to work because of sickness or disability 0.7 0.8 1.7 1.3 -0.1
Commuting to job workplace: Cycle 0.1 0.1 0.1 -0.3 0.2
Myopia 0.2 0.3 0.6 -0.8 0.2
Vascular/heart problems diagnosed by doctor 0.3 0.8 1.5 1.2 -0.1
Cholesterol lowering medication 0.1 0.2 0.4 -0.6 -0.2
Medication: Omeprazole (e.g. Zanprol) 0.2 0.2 0.3 0.2 0.6
Pain experienced in last month 0.9 1.5 2.5 0.7 1.6
Supplements: Calcium 0.1 0.2 0.3 -0.6 -0.0
Basal cell carcinoma (self-reported) 0.1 0.1 0.2 0.4 0.4
Heart attack/myocardial infarction (self-reported) 0.9 1.2 2.4 -1.6 -0.1
Deep venous thrombosis (DVT) (self-reported) 0.9 1.1 2.3 0.1 -1.5
Heart disease (siblings) 0.4 0.5 0.9 -1.0 -0.0
Alcohol drinker status: Previous 0.7 0.9 1.6 0.4 1.3
Pack years of smoking 1.9 2.8 5.4 -0.5 -2.3
Impedance of whole body 0.5 2.6 4.2 -2.0 -1.0
Leg fat mass (left) 0.8 2.9 5.3 2.3 -0.7
Arm predicted mass (left) 1.0 5.0 8.7 2.9 -1.2