[Hub]/) : Traits : Comparative body size at age 10 : ← →

chr11:46,543,524-48,783,497

Best TWAS P=8.14e-24 · Best GWAS P=3.01e-18 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
90	The Cancer Genome Atlas	Thyroid Carcinoma	C1QTNF4	0.04	0.01	blup	15	0.03	7.9e-04	8.66	-10.1	8.1e-24	-0.89	0.00	0.95	TRUE
91	The Cancer Genome Atlas	Thyroid Carcinoma	MADD	0.07	0.00	enet	11	0.03	6.7e-04	-4.48	8.6	1.1e-17	0.36	0.05	0.14	TRUE
84	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MADD	0.16	0.05	blup	64	0.08	2.2e-09	2.38	7.3	3.4e-13	0.10	0.97	0.01	TRUE
53	ROSMAP	Brain Pre-frontal Cortex	FNBP4	0.04	0.04	lasso	3	0.04	8.2e-06	-5.77	7.0	3.8e-12	0.69	0.95	0.05	TRUE
50	NTR	Blood	MADD	0.01	0.01	enet	8	0.01	4.7e-03	2.66	5.7	1.1e-08	-0.03	0.17	0.02	TRUE
27	GTEx	Heart Atrial Appendage	ACP2	0.10	0.12	enet	7	0.10	2.7e-05	-4.84	5.3	9.9e-08	0.49	0.32	0.07	TRUE
59	YFS	Blood	PTPMT1	0.03	0.01	lasso	5	0.01	3.2e-04	-5.68	-5.1	3.1e-07	-0.67	0.28	0.61	TRUE
78	The Cancer Genome Atlas	Brain Lower Grade Glioma	MADD	0.08	0.01	lasso	5	0.05	3.1e-06	7.01	9.7	2.2e-22	0.62	0.01	0.94	FALSE
64	The Cancer Genome Atlas	Breast Invasive Carcinoma	MADD	0.11	0.03	enet	14	0.06	1.4e-11	-6.69	9.7	2.6e-22	0.56	0.03	0.97	FALSE
31	GTEx	Liver	C1QTNF4	0.25	0.14	enet	16	0.20	2.3e-06	8.66	-9.5	3.0e-21	-0.84	0.01	0.98	FALSE
82	The Cancer Genome Atlas	Lung Adenocarcinoma	C1QTNF4	0.03	0.02	blup	15	0.02	1.3e-03	8.66	-9.4	5.9e-21	-0.97	0.00	0.97	FALSE
22	GTEx	Esophagus Mucosa	MADD	0.27	0.04	enet	18	0.12	4.1e-08	-4.77	9.0	3.1e-19	0.40	0.26	0.08	FALSE
85	The Cancer Genome Atlas	Prostate Adenocarcinoma	MADD	0.15	0.04	enet	10	0.06	4.5e-07	-6.69	8.8	1.3e-18	0.30	0.07	0.68	FALSE
75	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MADD	0.20	0.07	enet	9	0.08	2.4e-09	-6.69	8.8	1.7e-18	0.32	0.09	0.91	FALSE
7	GTEx	Artery Aorta	C1QTNF4	0.09	0.10	lasso	1	0.08	3.2e-05	8.66	-8.7	4.6e-18	-1.00	0.00	1.00	FALSE
23	GTEx	Esophagus Mucosa	C1QTNF4	0.10	0.11	lasso	1	0.10	5.0e-07	8.66	-8.7	4.6e-18	-1.00	0.00	1.00	FALSE
30	GTEx	Heart Left Ventricle	C1QTNF4	0.10	0.11	lasso	1	0.09	1.1e-05	8.66	-8.7	4.6e-18	-1.00	0.00	0.99	FALSE
67	The Cancer Genome Atlas	Colon Adenocarcinoma	C1QTNF4	0.12	0.12	lasso	1	0.12	1.6e-07	8.66	-8.7	4.6e-18	-1.00	0.00	1.00	FALSE
5	GTEx	Adipose Subcutaneous	C1QTNF4	0.16	0.22	lasso	4	0.22	2.5e-18	8.71	-8.6	1.2e-17	-0.98	0.00	1.00	FALSE
37	GTEx	Nerve Tibial	C1QTNF4	0.20	0.23	enet	12	0.23	1.7e-16	8.66	-8.6	1.2e-17	-0.96	0.00	1.00	FALSE
17	GTEx	Cells Transformed fibroblasts	MADD	0.19	0.00	enet	17	0.09	3.3e-07	-4.06	8.5	2.2e-17	0.30	0.54	0.04	FALSE
39	GTEx	Skin Not Sun Exposed Suprapubic	C1QTNF4	0.32	0.18	enet	33	0.20	5.2e-11	8.66	-8.5	2.7e-17	-0.90	0.00	1.00	FALSE
34	GTEx	Muscle Skeletal	C1QTNF4	0.09	0.14	lasso	3	0.13	9.9e-13	8.66	-8.4	3.2e-17	-0.98	0.00	1.00	FALSE
38	GTEx	Pituitary	MADD	0.42	0.32	lasso	6	0.39	8.9e-11	-6.14	8.4	5.0e-17	0.60	0.25	0.63	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FAM180B	0.07	0.08	lasso	3	0.08	9.1e-10	8.66	8.4	5.2e-17	0.95	0.01	0.99	FALSE
21	GTEx	Colon Transverse	C1QTNF4	0.07	0.02	lasso	6	0.03	2.0e-02	8.71	-8.2	1.9e-16	-0.96	0.01	0.96	FALSE
74	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1QTNF4	0.12	0.14	enet	4	0.16	6.5e-18	7.47	-8.2	2.9e-16	-0.95	0.03	0.97	FALSE
28	GTEx	Heart Atrial Appendage	C1QTNF4	0.26	0.14	lasso	9	0.17	3.9e-08	8.66	-8.2	3.1e-16	-0.95	0.01	0.99	FALSE
40	GTEx	Skin Sun Exposed Lower leg	C1QTNF4	0.25	0.22	lasso	12	0.23	4.2e-19	8.66	-8.2	3.3e-16	-0.95	0.00	1.00	FALSE
44	GTEx	Thyroid	MADD	0.11	0.00	enet	13	0.01	6.1e-02	1.83	8.2	3.7e-16	0.25	0.06	0.04	FALSE
70	The Cancer Genome Atlas	Esophageal Carcinoma	C1QTNF4	0.39	0.33	blup	15	0.35	6.1e-12	8.66	-8.1	4.5e-16	-0.98	0.00	1.00	FALSE
81	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PSMC3	0.09	0.07	blup	39	0.06	8.7e-04	7.21	8.1	6.3e-16	0.85	0.01	0.98	FALSE
61	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C1QTNF4	0.06	0.07	lasso	2	0.06	4.9e-06	7.54	-8.1	7.3e-16	-0.93	0.01	0.99	FALSE
86	The Cancer Genome Atlas	Prostate Adenocarcinoma	NUP160	0.03	0.02	enet	7	0.02	6.3e-03	6.97	8.0	1.0e-15	0.83	0.04	0.58	FALSE
88	The Cancer Genome Atlas	Stomach Adenocarcinoma	C1QTNF4	0.06	0.04	lasso	4	0.03	4.3e-03	7.54	-8.0	1.2e-15	-0.92	0.00	0.92	FALSE
11	GTEx	Brain Cerebellum	MADD	0.21	0.00	enet	13	0.11	3.3e-04	-3.90	8.0	1.6e-15	0.63	0.07	0.68	FALSE
15	GTEx	Breast Mammary Tissue (Female)	MADD	0.13	0.04	lasso	3	0.05	1.3e-02	7.25	7.9	3.0e-15	0.81	0.05	0.29	FALSE
24	GTEx	Esophagus Muscularis	MTCH2	0.09	0.04	lasso	6	0.02	1.8e-02	7.52	7.9	3.2e-15	0.78	0.27	0.52	FALSE
32	GTEx	Lung	C1QTNF4	0.18	0.15	lasso	6	0.13	3.2e-10	7.10	-7.8	5.4e-15	-0.91	0.08	0.92	FALSE
52	ROSMAP	Brain Pre-frontal Cortex	MTCH2	0.35	0.40	enet	9	0.40	4.7e-56	7.47	7.8	6.5e-15	0.91	0.96	0.04	FALSE
58	YFS	Blood	FNBP4	0.02	0.01	bslmm	301	0.01	8.9e-05	-7.60	7.8	6.5e-15	0.78	0.03	0.95	FALSE
35	GTEx	Nerve Tibial	NR1H3	0.10	0.00	enet	24	0.08	4.7e-06	-2.60	-7.7	1.2e-14	-0.52	0.02	0.82	FALSE
20	GTEx	Cells Transformed fibroblasts	NDUFS3	0.08	0.01	lasso	2	0.01	3.3e-02	8.71	-7.6	3.1e-14	-0.98	0.00	0.97	FALSE
73	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NUP160	0.08	0.03	blup	42	0.04	6.7e-05	7.00	7.6	3.5e-14	0.71	0.09	0.67	FALSE
19	GTEx	Cells Transformed fibroblasts	C1QTNF4	0.13	0.11	enet	19	0.12	5.2e-09	7.52	-7.5	4.7e-14	-0.84	0.02	0.98	FALSE
51	NTR	Blood	MTCH2	0.02	0.04	lasso	1	0.04	1.3e-11	7.52	-7.5	5.5e-14	-0.88	0.89	0.11	FALSE
71	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1QTNF4	0.06	0.08	lasso	3	0.08	7.5e-09	7.47	-7.5	5.6e-14	-0.88	0.04	0.96	FALSE
76	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1QTNF4	0.13	0.16	lasso	1	0.16	3.1e-09	7.51	-7.5	6.0e-14	-0.88	0.14	0.86	FALSE
79	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTCH2	0.11	0.11	lasso	2	0.10	6.4e-12	7.47	7.5	6.8e-14	0.87	0.09	0.91	FALSE
80	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C1QTNF4	0.19	0.19	lasso	3	0.19	3.2e-09	7.47	-7.5	6.8e-14	-0.87	0.09	0.91	FALSE
47	METSIM	Adipose	C1QTNF4	0.24	0.31	lasso	7	0.31	1.2e-46	7.47	-7.4	1.2e-13	-0.86	0.97	0.03	FALSE
25	GTEx	Esophagus Muscularis	MADD	0.13	0.07	enet	8	0.11	2.0e-07	-6.69	7.4	1.3e-13	0.17	0.73	0.01	FALSE
33	GTEx	Muscle Skeletal	MTCH2	0.05	0.03	enet	15	0.04	1.5e-04	6.97	7.4	1.3e-13	0.84	0.05	0.94	FALSE
41	GTEx	Spleen	C1QTNF4	0.31	0.28	enet	29	0.34	1.8e-09	6.98	-7.4	1.4e-13	-0.89	0.07	0.93	FALSE
89	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MADD	0.21	0.04	blup	64	0.07	1.3e-03	-4.28	7.3	2.3e-13	0.28	0.07	0.06	FALSE
63	The Cancer Genome Atlas	Breast Invasive Carcinoma	C1QTNF4	0.02	0.01	lasso	5	0.02	2.1e-04	-4.32	-7.3	2.6e-13	-0.74	0.01	0.83	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MADD	0.32	0.17	bslmm	315	0.18	1.4e-21	-6.69	7.2	4.2e-13	0.19	1.00	0.00	FALSE
77	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PSMC3	0.07	0.07	enet	7	0.06	1.4e-04	7.25	7.2	4.7e-13	0.82	0.01	0.97	FALSE
29	GTEx	Heart Left Ventricle	MADD	0.14	0.01	enet	17	0.05	7.0e-04	-4.23	7.2	6.7e-13	0.70	0.02	0.96	FALSE
45	GTEx	Whole Blood	C1QTNF4	0.09	0.05	lasso	3	0.03	1.4e-03	6.99	-7.1	1.0e-12	-0.86	0.17	0.74	FALSE
16	GTEx	Cells Transformed fibroblasts	FNBP4	0.11	0.05	lasso	8	0.08	1.6e-06	-5.67	7.1	1.7e-12	0.88	0.04	0.96	FALSE
42	GTEx	Testis	MTCH2	0.17	0.16	lasso	3	0.16	1.0e-07	7.00	7.0	1.9e-12	0.83	0.53	0.47	FALSE
13	GTEx	Brain Cortex	C1QTNF4	0.26	0.04	lasso	8	0.02	1.2e-01	-5.66	-6.9	4.4e-12	-0.80	0.02	0.58	FALSE
57	YFS	Blood	DDB2	0.02	0.00	bslmm	306	0.01	1.9e-04	-4.32	6.9	6.7e-12	0.20	0.24	0.06	FALSE
65	The Cancer Genome Atlas	Breast Invasive Carcinoma	MYBPC3	0.02	0.01	blup	43	0.01	3.4e-03	7.10	-6.9	6.9e-12	-0.74	0.01	0.97	FALSE
14	GTEx	Breast Mammary Tissue	C1QTNF4	0.10	0.06	lasso	2	0.03	8.5e-03	7.00	-6.7	2.2e-11	-0.82	0.10	0.68	FALSE
54	ROSMAP	Brain Pre-frontal Cortex	MADD	0.33	0.16	enet	23	0.23	1.9e-29	-6.69	6.6	3.6e-11	0.08	1.00	0.00	FALSE
12	GTEx	Brain Cortex	MTCH2	0.21	0.19	lasso	6	0.16	4.0e-05	6.98	6.5	6.0e-11	0.79	0.35	0.18	FALSE
69	The Cancer Genome Atlas	Colon Adenocarcinoma	NUP160	0.05	0.05	blup	44	0.05	7.7e-04	-5.75	6.5	9.7e-11	0.82	0.07	0.29	FALSE
26	GTEx	Esophagus Muscularis	C1QTNF4	0.10	0.05	enet	23	0.06	1.4e-04	8.71	-6.5	9.9e-11	-0.93	0.01	0.99	FALSE
36	GTEx	Nerve Tibial	PTPRJ	0.05	0.03	enet	13	0.03	2.7e-03	-4.73	-6.5	1.0e-10	-0.50	0.19	0.08	FALSE
43	GTEx	Testis	C1QTNF4	0.14	0.12	lasso	4	0.11	1.6e-05	-5.75	-6.4	1.7e-10	-0.73	0.28	0.67	FALSE
56	ROSMAP	Brain Pre-frontal Cortex	C1QTNF4	0.05	0.06	blup	281	0.06	1.7e-08	7.19	-6.4	2.0e-10	-0.86	0.07	0.93	FALSE
6	GTEx	Artery Aorta	MADD	0.09	0.03	enet	22	0.04	1.9e-03	-7.12	6.3	3.0e-10	0.12	0.14	0.04	FALSE
48	METSIM	Adipose	MYBPC3	0.11	0.10	enet	26	0.11	1.0e-15	7.00	-6.1	9.5e-10	-0.81	0.29	0.71	FALSE
83	The Cancer Genome Atlas	Lung Adenocarcinoma	MYBPC3	0.04	0.02	enet	10	0.04	2.9e-05	7.10	-6.0	1.5e-09	-0.68	0.01	0.98	FALSE
62	The Cancer Genome Atlas	Breast Invasive Carcinoma	ACP2	0.02	0.01	blup	44	0.02	2.7e-04	-3.90	6.0	1.8e-09	0.50	0.05	0.02	FALSE
68	The Cancer Genome Atlas	Colon Adenocarcinoma	KBTBD4	0.14	0.01	blup	13	0.02	1.6e-02	-5.71	6.0	2.0e-09	0.90	0.00	0.40	FALSE
9	GTEx	Brain Cerebellar Hemisphere	MADD	0.44	0.14	lasso	7	0.21	4.0e-06	-2.05	5.9	4.2e-09	0.50	0.33	0.19	FALSE
4	GTEx	Adipose Subcutaneous	ACP2	0.08	0.03	enet	18	0.03	3.5e-03	-2.05	5.9	4.5e-09	0.73	0.08	0.78	FALSE
87	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMC3	0.02	0.02	blup	39	0.02	5.7e-03	7.00	5.8	7.3e-09	0.78	0.01	0.63	FALSE
72	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MYBPC3	0.05	0.03	blup	43	0.04	6.0e-05	5.74	-5.8	8.2e-09	-0.71	0.01	0.98	FALSE
10	GTEx	Brain Cerebellar Hemisphere	RP11-750H9.5	0.17	0.25	lasso	6	0.21	3.5e-06	-5.61	5.6	2.1e-08	0.29	0.43	0.06	FALSE
49	NTR	Blood	ACP2	0.01	0.00	enet	7	0.01	2.5e-03	-4.48	5.6	2.2e-08	0.44	0.44	0.09	FALSE
55	ROSMAP	Brain Pre-frontal Cortex	ACP2	0.03	0.00	blup	295	0.02	1.5e-03	7.01	5.5	3.2e-08	0.72	0.06	0.86	FALSE
46	METSIM	Adipose	ACP2	0.05	0.04	blup	302	0.06	1.7e-09	7.00	5.4	5.9e-08	0.67	0.32	0.68	FALSE
66	The Cancer Genome Atlas	Breast Invasive Carcinoma	NUP160	0.03	0.01	blup	44	0.01	1.9e-03	6.96	5.4	6.7e-08	0.58	0.02	0.13	FALSE
60	YFS	Blood	SPI1	0.65	0.18	enet	75	0.27	1.6e-87	7.16	-5.4	7.1e-08	-0.62	1.00	0.00	FALSE
8	GTEx	Artery Tibial	MADD	0.09	0.00	enet	13	0.02	1.1e-02	-2.65	5.3	9.5e-08	0.05	0.46	0.03	FALSE
3	CommonMind	Brain Pre-frontal Cortex	MTCH2	0.03	0.00	bslmm	299	0.00	1.1e-01	-0.82	5.2	1.8e-07	0.68	0.07	0.53	FALSE
18	GTEx	Cells Transformed fibroblasts	PSMC3	0.07	0.00	enet	13	0.02	2.3e-02	-1.47	5.2	1.8e-07	0.83	0.03	0.77	FALSE