[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr2:23,453,834-26,262,948

Best TWAS P=4.49e-25 · Best GWAS P=5.33e-31 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	GTEx	Esophagus Muscularis	NCOA1	0.11	0.01	enet	9	0.01	5.8e-02	-7.44	-10.3	4.5e-25	-0.17	0.08	0.05	TRUE
8	GTEx	Adrenal Gland	PTRHD1	0.32	0.28	lasso	3	0.26	8.3e-10	9.15	-9.2	2.6e-20	-0.20	0.98	0.00	TRUE
16	GTEx	Colon Sigmoid	DNMT3A	0.19	-0.01	lasso	8	0.00	4.5e-01	-4.44	-9.1	9.9e-20	-0.40	0.05	0.40	TRUE
36	YFS	Blood	CENPO	0.09	0.06	lasso	6	0.07	6.7e-21	-8.27	8.6	8.8e-18	0.11	1.00	0.00	TRUE
33	NTR	Blood	ITSN2	0.02	0.00	bslmm	345	0.01	2.9e-03	-8.51	8.2	2.7e-16	0.06	0.05	0.05	TRUE
17	GTEx	Colon Transverse	UBXN2A	0.11	0.01	enet	8	0.03	8.7e-03	-5.86	-7.5	7.6e-14	-0.07	0.07	0.71	TRUE
12	GTEx	Artery Tibial	RP11-443B20.1	0.17	0.08	enet	40	0.09	8.2e-08	-6.84	-6.8	1.2e-11	-0.34	0.92	0.01	TRUE
49	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	POMC	0.19	0.01	blup	38	0.05	1.5e-04	9.52	6.7	2.1e-11	0.31	0.02	0.06	TRUE
26	GTEx	Small Intestine Terminal Ileum	UBXN2A	0.18	0.08	enet	33	0.16	2.5e-04	-7.11	-6.6	3.5e-11	-0.02	0.03	0.91	TRUE
18	GTEx	Esophagus Mucosa	TP53I3	0.16	0.03	enet	23	0.06	8.2e-05	0.95	-6.5	6.3e-11	-0.03	0.11	0.07	TRUE
3	GTEx	Adipose Subcutaneous	TP53I3	0.11	0.03	enet	48	0.04	3.8e-04	-1.38	6.0	2.5e-09	0.04	0.11	0.67	TRUE
1	CommonMind	Brain Pre-frontal Cortex	ADCY3	0.16	0.12	lasso	10	0.14	3.2e-17	-7.82	5.4	6.9e-08	0.27	1.00	0.00	TRUE
41	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	POMC	0.06	0.00	enet	12	0.03	9.3e-05	0.35	5.2	2.0e-07	0.17	0.02	0.04	TRUE
13	GTEx	Cells EBV-transformed lymphocytes	ADCY3	0.25	0.23	enet	10	0.12	9.2e-05	-7.92	10.2	1.6e-24	0.38	0.77	0.05	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	RP11-443B20.1	0.13	0.13	enet	9	0.05	9.2e-03	-7.92	9.2	4.4e-20	0.38	0.35	0.07	FALSE
9	GTEx	Artery Aorta	NCOA1	0.15	0.00	enet	15	0.01	1.4e-01	-8.05	-9.1	9.5e-20	-0.23	0.06	0.17	FALSE
27	GTEx	Spleen	UBXN2A	0.31	0.11	enet	19	0.17	4.1e-05	7.57	-8.5	1.7e-17	-0.06	0.04	0.92	FALSE
42	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADCY3	0.08	0.03	enet	16	0.03	1.5e-04	-8.54	8.3	1.0e-16	0.07	0.03	0.16	FALSE
24	GTEx	Nerve Tibial	ADCY3	0.09	0.05	enet	6	0.03	2.2e-03	-6.84	8.3	1.5e-16	0.35	0.96	0.00	FALSE
45	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY3	0.03	0.02	blup	81	0.02	7.1e-04	-7.50	8.1	5.2e-16	0.34	0.51	0.03	FALSE
40	The Cancer Genome Atlas	Glioblastoma Multiforme	ADCY3	0.36	0.14	enet	7	0.13	8.9e-05	-8.04	8.0	1.3e-15	0.11	0.04	0.06	FALSE
50	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EFR3B	0.26	0.01	lasso	4	0.05	3.8e-03	-7.44	-8.0	1.9e-15	-0.21	0.03	0.11	FALSE
34	ROSMAP	Brain Pre-frontal Cortex	ADCY3	0.17	0.26	enet	32	0.26	6.8e-33	-7.49	7.8	4.0e-15	0.37	1.00	0.00	FALSE
4	GTEx	Adipose Subcutaneous	ADCY3	0.07	0.04	lasso	6	0.01	3.2e-02	-7.92	-7.8	6.8e-15	-0.32	0.83	0.01	FALSE
38	The Cancer Genome Atlas	Breast Invasive Carcinoma	ADCY3	0.05	0.03	blup	81	0.03	5.0e-07	-8.59	7.7	1.9e-14	0.18	0.44	0.52	FALSE
28	GTEx	Whole Blood	DNAJC27	0.08	0.10	lasso	1	0.10	2.2e-09	-7.53	-7.5	5.3e-14	-0.34	1.00	0.00	FALSE
29	GTEx	Whole Blood	ADCY3	0.23	0.24	enet	24	0.27	5.5e-25	-7.49	-7.4	1.9e-13	-0.32	1.00	0.00	FALSE
43	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EFR3B	0.03	0.05	lasso	1	0.04	1.9e-05	7.35	7.3	2.0e-13	0.34	0.17	0.72	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CENPO	0.07	0.03	bslmm	322	0.03	7.0e-05	-1.02	7.1	9.5e-13	0.25	0.63	0.01	FALSE
37	YFS	Blood	POMC	0.35	0.05	enet	71	0.19	5.7e-59	9.52	7.1	1.2e-12	0.26	1.00	0.00	FALSE
31	GTEx	Whole Blood	RP11-443B20.1	0.21	0.17	enet	32	0.20	1.8e-18	-7.53	-7.0	2.6e-12	-0.32	1.00	0.00	FALSE
10	GTEx	Artery Tibial	ADCY3	0.21	0.14	lasso	6	0.15	4.3e-12	-6.84	-6.8	1.1e-11	-0.27	1.00	0.00	FALSE
6	GTEx	Adipose Visceral Omentum	NCOA1	0.11	0.02	enet	17	0.02	2.1e-02	-8.12	-6.7	1.6e-11	-0.11	0.18	0.04	FALSE
25	GTEx	Nerve Tibial	RP11-443B20.1	0.07	0.03	enet	6	0.02	1.1e-02	-6.84	6.6	3.5e-11	0.29	0.74	0.02	FALSE
46	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJC27	0.05	0.01	blup	46	0.04	3.2e-05	-3.19	6.6	5.5e-11	0.27	0.44	0.49	FALSE
35	ROSMAP	Brain Pre-frontal Cortex	CENPO	0.08	0.04	enet	5	0.05	2.6e-07	6.35	6.5	6.9e-11	0.16	1.00	0.00	FALSE
30	GTEx	Whole Blood	UBXN2A	0.17	0.07	lasso	8	0.09	2.1e-08	-2.74	-6.4	1.3e-10	-0.04	0.05	0.95	FALSE
39	The Cancer Genome Atlas	Breast Invasive Carcinoma	FKBP1B	0.04	0.02	blup	41	0.02	3.6e-05	-4.98	6.3	2.5e-10	0.01	0.43	0.06	FALSE
51	The Cancer Genome Atlas	Prostate Adenocarcinoma	ADCY3	0.09	0.02	enet	11	0.04	3.2e-05	-8.04	6.1	1.2e-09	-0.02	0.12	0.05	FALSE
21	GTEx	Lung	NCOA1	0.12	0.04	lasso	7	0.06	1.9e-05	-1.06	-6.0	2.3e-09	-0.10	0.52	0.02	FALSE
23	GTEx	Muscle Skeletal	POMC	0.38	0.10	lasso	9	0.09	2.9e-09	2.16	5.7	1.6e-08	0.29	1.00	0.00	FALSE
7	GTEx	Adipose Visceral Omentum	UBXN2A	0.10	0.08	enet	29	0.03	9.8e-03	-7.22	-5.6	1.9e-08	-0.02	0.06	0.92	FALSE
22	GTEx	Lung	UBXN2A	0.09	0.06	enet	7	0.07	6.1e-06	-2.73	-5.6	1.9e-08	-0.05	0.34	0.65	FALSE
48	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ADCY3	0.06	0.01	enet	9	0.02	1.0e-03	-8.51	5.5	3.6e-08	0.04	0.05	0.06	FALSE
20	GTEx	Heart Left Ventricle	PFN4	0.23	0.28	lasso	6	0.28	4.1e-15	-5.00	-5.5	4.3e-08	-0.01	1.00	0.00	FALSE
32	METSIM	Adipose	EFR3B	0.04	0.00	bslmm	357	0.00	9.7e-02	5.87	5.5	4.9e-08	-0.04	0.06	0.04	FALSE
11	GTEx	Artery Tibial	UBXN2A	0.12	0.06	enet	24	0.09	1.5e-07	-2.79	-5.5	5.0e-08	-0.05	0.90	0.10	FALSE
5	GTEx	Adipose Subcutaneous	RP11-443B20.1	0.04	0.00	enet	10	0.00	1.2e-01	-2.27	-5.3	1.1e-07	-0.28	0.36	0.05	FALSE
44	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	NCOA1	0.08	0.07	blup	77	0.05	5.8e-04	0.32	-5.3	1.1e-07	-0.07	0.27	0.04	FALSE
14	GTEx	Cells EBV-transformed lymphocytes	PFN4	0.18	0.13	lasso	12	0.12	8.9e-05	-4.98	-5.3	1.4e-07	0.00	0.34	0.05	FALSE
52	The Cancer Genome Atlas	Rectum Adenocarcinoma	PFN4	0.38	0.11	lasso	5	0.05	2.8e-02	-4.98	-5.3	1.4e-07	-0.01	0.01	0.56	FALSE
47	The Cancer Genome Atlas	Lung Adenocarcinoma	NCOA1	0.02	0.01	blup	77	0.01	1.2e-02	1.30	5.2	2.1e-07	0.15	0.04	0.66	FALSE