TWAS hub - FKBP1B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.0954	0.0406	1.6e-04	0.062	NA	0.035	NA	0.040	1.3e-05	NA	8.6e-04	NA	4.4e-04
2	GTEx	Brain Cerebellum	0.2530	0.0880	4.9e-04	0.012	NA	0.198	NA	0.121	1.4e-01	NA	1.6e-06	NA	2.0e-04
3	METSIM	Adipose	0.2020	0.0435	2.6e-12	0.044	0.101	0.094	0.100	0.074	3.6e-07	6.5e-15	7.0e-14	1.1e-14	3.0e-11
4	ROSMAP	Brain Pre-frontal Cortex	0.0587	0.0218	5.4e-05	0.026	0.025	0.021	0.026	0.036	2.5e-04	2.8e-04	9.0e-04	2.4e-04	2.0e-05
5	YFS	Blood	0.0826	0.0250	2.2e-06	0.026	0.023	0.031	0.031	0.029	5.5e-09	3.2e-08	1.6e-10	2.0e-10	7.6e-10
6	TCGA	Breast Invasive Carcinoma	0.0372	0.0183	4.3e-05	0.024	0.020	0.016	NA	0.018	9.1e-06	3.6e-05	2.0e-04	NA	1.0e-04
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0518	0.0254	1.2e-06	0.067	0.055	0.060	NA	0.060	5.7e-08	8.8e-07	2.8e-07	NA	2.3e-07
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1010	0.0550	8.2e-04	0.012	0.016	0.013	NA	0.010	6.8e-02	3.9e-02	5.8e-02	NA	7.8e-02
9	TCGA	Thyroid Carcinoma	0.0440	0.0230	6.3e-04	0.017	0.038	0.040	NA	0.039	8.4e-03	1.3e-04	9.0e-05	NA	1.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Blood Red Count	6.5	62.5	124.5	-5.4	9.7	-8.9	7.3	0.7	-10.8	-5.6	-5.7	-11.2
HbA1C	4.7	5.2	16.2	-1.4	1.2	-1.9	2.9	-0.9	-2.7	-2.4	-1.3	-4.0
Age when periods started (menarche)	4.0	9.7	18.5	-0.7	3.9	-4.3	1.9	0.6	-4.2	-2.9	-3.0	-3.8
Severe depression (siblings)	3.7	4.1	7.1	1.9	-2.5	2.0	-1.9	-0.6	1.9	2.4	1.8	2.7
Alcohol intake frequency.	3.6	8.4	29.7	0.3	3.6	-2.8	0.5	1.3	-5.5	-1.3	-3.1	-3.4
Qualifications: nursing, teaching	3.6	5.5	11.3	0.2	-3.4	3.3	-1.0	-0.4	3.3	1.8	2.5	2.5
Average weekly fortified wine intake	3.5	4.1	8.0	0.8	-2.6	2.8	-1.6	-1.5	2.3	1.6	1.5	2.5
Type 2 Diabetes (T2D) (2012)	3.4	3.9	6.2	-1.5	1.8	-2.4	2.5	-2.0	-1.6	-2.1	-1.7	-1.9
Chronotype (morning person)	3.0	6.9	13.0	-1.3	2.4	-3.4	1.6	-2.2	-3.6	-2.3	-2.5	-3.4
Other serious medical condition/disability diagnosed by doctor	2.7	3.5	6.4	-2.3	1.6	-0.9	2.5	-0.3	-1.8	-2.1	-1.6	-2.5
Suffer from ‘nerves’	2.5	4.0	12.6	3.5	-0.2	-0.6	-3.3	-0.5	0.5	2.4	2.0	1.5
Mouth/teeth dental problems: Mouth ulcers	2.5	3.9	11.0	1.0	-1.8	1.8	-0.7	1.5	3.3	1.8	2.5	2.2
Medication: Paracetamol	2.5	3.8	8.9	-1.2	2.9	-1.0	1.9	-1.6	-1.5	-2.3	-0.9	-3.0
Whole body water mass	2.4	13.7	37.7	1.9	-4.1	4.8	-0.6	0.5	6.1	2.2	4.8	3.8
Impedance of leg (right)	2.3	11.0	21.8	-2.2	4.4	-4.7	2.9	-0.9	-3.4	-2.9	-2.0	-4.5
Sitting height	2.3	16.0	53.7	-2.0	-6.7	1.8	3.6	-2.7	7.3	-1.0	3.0	2.9
Comparative body size at age 10	2.3	6.2	19.2	2.4	1.7	4.4	-2.6	2.0	0.5	3.0	2.4	1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.7	7.9	1.6	-2.8	0.5	-1.0	0.1	1.6	1.9	0.7	2.5
Leg fat-free mass (right)	2.3	12.2	26.9	2.4	-4.2	4.4	-1.5	0.5	5.2	2.5	3.9	4.0
Asthma (self-reported)	2.3	4.6	11.2	1.2	-1.6	2.6	-1.3	3.3	2.2	2.1	1.5	2.7
Leg predicted mass (right)	2.3	12.0	27.0	2.4	-4.2	4.3	-1.5	0.5	5.2	2.4	3.9	4.0
Arm fat-free mass (right)	2.2	11.4	31.4	1.9	-3.4	4.4	-0.5	0.5	5.6	2.0	4.8	3.1
Mean time to correctly identify matches	2.2	4.2	13.8	-0.8	-3.4	1.5	-0.0	-1.2	3.7	0.5	1.7	2.3
Whole body fat-free mass	2.2	12.8	36.0	1.7	-4.0	4.6	-0.4	0.5	6.0	2.1	4.6	3.6
Arm fat-free mass (left)	2.2	11.0	28.7	1.6	-3.5	4.6	-0.4	0.9	5.4	2.0	4.4	3.1
Respiratory disease	2.1	4.7	10.0	2.5	-1.5	2.2	-2.2	3.2	1.8	1.8	1.3	2.5
Leg fat-free mass (left)	2.1	11.1	24.5	2.3	-3.8	4.3	-1.4	0.6	5.0	2.4	4.0	3.7
Leg predicted mass (left)	2.1	11.1	24.3	2.3	-3.7	4.3	-1.5	0.6	4.9	2.4	4.0	3.7
Trunk fat-free mass	2.1	12.1	39.4	1.2	-3.7	4.3	0.3	0.3	6.3	1.6	4.7	3.3
Hip circumference	2.1	8.9	17.6	3.1	-2.5	4.2	-2.8	1.4	2.7	3.2	3.3	3.0
Arm predicted mass (right)	2.1	11.0	29.9	1.7	-3.3	4.3	-0.5	0.8	5.5	2.0	4.7	3.0
Comparative height size at age 10	2.1	11.3	39.9	1.4	-3.3	2.9	0.5	-1.4	6.3	1.8	5.0	3.1
Knee pain experienced in last month	2.1	3.3	10.0	0.4	-1.7	3.2	-1.7	1.8	1.7	1.4	1.9	1.5
Average weekly champagne plus white wine intake	2.1	2.8	6.6	-0.3	-2.1	2.6	-0.6	0.2	2.4	1.2	1.3	2.2
Basal metabolic rate	2.1	11.8	29.7	2.1	-3.7	4.5	-0.9	0.8	5.5	2.3	4.5	3.5
Arm predicted mass (left)	2.1	10.9	28.0	1.7	-3.5	4.4	-0.4	0.6	5.3	2.2	4.6	3.0
Asthma	2.0	3.9	11.2	1.0	-1.4	2.2	-1.2	3.3	1.9	1.8	1.2	2.4
Trunk predicted mass	2.0	11.5	37.7	1.2	-3.6	4.2	0.3	0.2	6.1	1.5	4.6	3.1
Worry too long after embarrassment	2.0	3.3	6.1	2.0	-0.8	1.7	-2.4	-0.9	1.2	2.5	2.1	1.9
Worry (Nagel 2018)	1.9	4.0	11.0	3.3	-0.4	-0.6	-2.6	-2.1	1.6	1.7	2.0	1.8
Fed-up feelings	1.9	3.5	17.1	1.8	4.1	-0.5	-0.8	0.3	-1.8	0.7	1.5	-2.2
Impedance of leg (left)	1.9	9.0	19.3	-1.7	4.0	-4.4	2.2	-0.7	-3.4	-2.3	-1.9	-4.1
Number of incorrect matches in round	1.9	3.1	12.1	3.5	-1.0	0.0	-2.8	-1.1	0.6	1.4	1.6	1.0
Medication: Seretide 50 evohaler	1.9	2.2	5.2	-1.2	0.2	-1.3	2.2	1.9	0.1	-2.3	-1.4	-1.1
Wears glasses or contact lenses	1.9	2.2	5.5	1.8	-0.6	1.7	-1.9	0.3	0.5	2.3	1.3	1.6
Medication: Bendroflumethiazide	1.9	2.8	8.8	2.6	0.2	1.1	-1.8	1.4	0.8	1.6	3.0	-0.0
Depressed Affect (Nagel 2018)	1.8	3.8	19.9	1.9	4.5	-1.0	-0.6	-0.6	-0.8	-0.0	1.7	-2.2
Current tobacco smoking	1.8	2.9	10.0	-0.9	3.2	-0.3	1.4	0.8	-2.3	-1.1	-1.4	-2.1
Hair/balding pattern: Pattern 3	1.8	2.8	7.2	-0.8	2.7	-2.0	0.3	-0.5	-2.4	-1.4	-1.1	-2.0
Pulse wave Arterial Stiffness index	1.8	2.1	6.8	0.3	-1.8	0.2	-0.5	-0.8	2.6	1.3	1.7	2.0
Qualifications: College or University degree	1.8	5.7	22.0	0.6	-1.7	3.0	-0.7	-0.7	4.7	1.2	2.7	2.8
Fractured/broken bones in last 5 years	1.8	2.3	5.3	1.7	0.1	1.0	-1.0	1.3	1.7	2.1	2.3	1.3
Age started oral contraceptive pill	1.8	2.3	3.9	1.0	-2.0	1.9	-1.7	1.1	1.4	1.4	1.2	1.5
Commuting to job workplace: Cycle	1.8	2.2	4.9	0.5	-1.8	2.2	-1.0	0.6	1.6	1.5	0.8	2.0
Supplements: Glucosamine	1.7	2.3	6.1	-0.6	-1.9	1.4	-1.2	-0.7	2.5	1.0	1.0	2.1
Weight	1.7	8.4	15.8	2.9	-2.6	4.0	-1.9	1.4	3.2	2.8	3.8	2.7
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.2	16.1	0.8	4.0	-0.5	-0.2	-0.3	-0.3	0.0	0.9	-1.2
Medication: Paracetamol	1.7	2.8	7.7	-1.0	2.6	-0.9	1.4	-1.1	-1.6	-1.7	-0.5	-2.8
Exposure to tobacco smoke outside home	1.7	2.2	5.4	-1.7	1.9	-2.3	0.9	-1.6	-0.8	-1.3	-0.5	-1.4
Medication: Ibuprofen	1.7	2.1	14.2	1.2	3.8	-0.3	-0.4	-0.1	0.1	0.5	1.4	-0.8
Number of full sisters	1.7	2.0	5.2	0.5	-0.2	2.3	-1.0	1.2	0.8	2.2	1.7	1.3
Reaction Time	1.6	3.1	9.8	-2.0	-2.6	0.7	1.5	-1.2	3.1	-1.3	0.4	1.1
Systolic blood pressure, automated reading	1.6	4.7	17.6	3.4	0.2	0.1	-4.2	0.3	0.3	2.6	2.0	1.4
Qualifications: CSEs or equivalent	1.6	2.1	5.5	-0.7	1.8	-1.8	0.3	0.9	-2.3	-0.8	-1.8	-1.2
Medication: Lansoprazole	1.6	1.8	5.2	1.1	-0.3	0.9	-1.8	0.3	0.8	2.0	2.3	0.8
Birth weight	1.6	3.5	11.0	1.7	-1.5	1.9	-0.7	-0.2	3.3	0.9	2.2	2.4
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.3	10.7	1.7	-0.9	0.7	-0.9	-0.2	3.3	1.6	2.6	2.2
Impedance of whole body	1.6	8.3	22.0	-1.1	3.2	-4.7	1.7	-1.9	-3.4	-2.3	-2.3	-3.5
Prostate Cancer	1.5	2.2	3.5	1.0	-1.8	1.4	-0.9	1.5	1.9	1.2	1.3	1.8
HDL Cholesterol	1.5	2.4	4.8	1.2	-0.4	2.2	-2.0	0.6	1.6	1.5	1.9	1.6
Blood White Count	1.5	11.4	42.5	1.2	6.5	-0.9	-0.3	3.6	-5.1	0.9	0.4	-4.2
Waist circumference	1.5	5.5	13.2	3.6	-0.9	2.7	-2.6	0.9	1.3	2.7	3.0	1.4
Qualifications: None of the above	1.5	3.1	10.4	0.7	1.7	-2.0	0.9	-1.0	-3.2	-0.7	-1.4	-2.4
Shortness of breath walking on level ground	1.5	1.8	4.2	2.0	1.1	-2.0	-0.6	-0.6	-1.9	0.1	0.1	-1.5
Age at last live birth	1.5	2.1	5.2	1.1	-1.6	1.1	-1.1	0.7	2.3	1.1	1.4	1.9
Smoking status: Previous	1.5	2.2	4.7	1.2	-1.1	0.8	-0.8	-0.9	2.2	1.7	2.1	1.8
Neuroticism (Nagel 2018)	1.4	3.3	10.0	3.2	1.9	-0.3	-1.9	-1.9	1.1	1.3	2.5	0.2
BMI	1.4	8.2	22.6	2.7	-0.7	4.8	-3.5	2.6	1.3	3.3	2.2	2.7
Relative age voice broke	1.4	2.1	5.6	0.1	2.0	-0.9	0.6	-0.9	-2.4	-1.1	-1.9	-1.5
Pulse wave reflection index	1.4	1.7	4.1	1.1	-1.0	-0.0	-2.0	0.4	0.9	2.0	1.2	1.6
Qualifications: O levels/GCSEs or equivalent	1.4	2.3	8.9	-3.0	0.3	-0.6	2.0	-0.6	0.9	-2.2	-1.1	-0.5
Emphysema/chronic bronchitis	1.4	1.6	3.2	-0.5	0.8	-0.8	1.6	-1.7	-0.6	-1.8	-1.2	-1.3
Average weekly red wine intake	1.4	2.0	6.2	-1.2	-1.9	1.7	0.0	0.2	2.5	0.4	0.9	1.8
Osteoarthritis (self-reported)	1.4	1.8	5.7	-0.3	0.2	2.4	-0.9	0.3	1.8	1.3	1.8	1.3
Smoking status: Current	1.4	2.2	9.1	-0.5	3.0	-0.1	1.1	0.7	-1.7	-1.0	-1.1	-1.8
Miserableness	1.4	2.5	16.7	0.5	4.1	-0.6	-0.1	-0.3	-0.8	-0.1	1.2	-1.8
Mother’s age at death	1.4	1.7	4.5	0.3	-0.9	1.0	-1.7	2.1	1.0	1.4	1.6	0.9
Alzheimer’s Disease (in father)	1.3	1.4	6.7	-1.1	-2.6	0.4	0.6	0.9	0.4	-0.8	-1.3	0.7
Mean Putamen Volume	1.3	1.5	2.5	1.6	-1.5	1.6	-0.9	0.5	1.2	0.8	0.7	1.5
Height	1.3	25.3	98.0	0.4	-6.0	1.0	4.1	-5.4	9.9	-0.8	6.3	2.5
Sensitivity / hurt feelings	1.3	2.3	7.5	0.6	-2.7	1.8	-1.2	0.8	1.0	1.2	0.2	2.2
Frequency of depressed mood in last 2 weeks	1.3	1.8	4.4	1.8	1.1	-0.7	-1.8	-0.9	0.3	1.7	2.1	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	4.9	1.0	1.3	-2.2	-0.8	-1.7	-1.6	0.1	0.1	-1.5
Body mass index (BMI)	1.3	5.3	11.6	2.7	-0.6	3.4	-2.9	2.6	0.2	2.8	1.8	1.6
Arm fat mass (right)	1.3	5.5	9.9	3.1	-1.0	3.1	-2.6	1.5	1.2	2.8	2.6	1.8
Peak expiratory flow (PEF)	1.3	3.0	9.0	0.6	-2.1	2.1	-0.4	-0.6	3.0	1.0	1.7	2.2
Medication: Ventolin 100micrograms inhaler	1.3	1.7	7.3	0.7	0.2	0.9	-1.3	2.7	0.9	1.2	0.9	1.3
Illness, injury, bereavement, stress in last 2 years	1.3	1.5	4.4	0.3	-1.2	0.4	-0.7	-0.3	2.0	1.3	2.1	1.2
Commuting to job workplace: Walk	1.3	1.5	3.4	1.9	0.1	0.5	-1.8	-0.4	1.6	0.7	1.4	1.1
Heart attack/myocardial infarction (self-reported)	1.3	1.6	3.3	-1.8	0.8	-0.8	1.5	-0.4	-1.1	-1.6	-1.4	-1.3
Lung FVC	1.2	6.0	22.0	-4.7	0.3	0.0	4.5	-0.0	0.7	-2.8	-1.2	-1.4
Supplements: Zinc	1.2	1.3	4.3	-1.2	-1.5	0.1	1.0	-2.1	1.0	-0.7	-0.8	0.6
Heart attack	1.2	1.5	2.6	-1.6	0.7	-0.8	1.4	-0.4	-1.3	-1.5	-1.4	-1.4
Fluid intelligence score	1.2	2.6	7.6	0.2	-0.7	1.9	-0.2	-0.3	2.8	1.5	2.3	1.9
Illnesses of siblings	1.2	1.6	4.8	-2.2	-1.8	-0.2	1.5	-0.2	1.7	-0.3	-0.4	1.1
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	5.8	-0.0	2.4	-1.8	0.0	-1.4	-1.4	-0.5	0.3	-2.0
Standing height	1.2	12.3	48.6	0.8	-4.4	1.7	2.1	-2.6	7.0	0.3	4.8	2.4
Chronic bronchitis/emphysema (mother)	1.2	1.4	5.7	1.8	2.4	-0.6	-0.5	-1.1	0.3	-0.8	0.6	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	5.1	2.3	-1.3	-0.9	-1.3	-1.5	0.8	0.8	0.6	1.1
Age at first live birth	1.2	2.0	4.1	1.6	-0.7	0.6	-1.6	-0.4	2.0	1.4	1.9	1.7
Pulse wave peak to peak time	1.2	1.4	4.2	-0.3	1.3	0.0	0.6	0.8	-2.0	-1.1	-1.3	-1.6
Had major operations	1.2	1.5	5.2	-2.3	-1.0	0.4	1.8	-0.5	0.5	-1.4	-1.0	-0.4
Supplements: Vitamin C	1.2	1.4	6.1	-0.1	-0.6	-1.4	0.9	-2.5	0.0	-1.2	-1.2	-0.1
Ever had bowel cancer screening	1.2	1.4	5.9	0.4	-1.0	1.4	-0.0	0.6	2.4	0.0	1.6	1.1
Mineral and other dietary supplements	1.2	1.6	4.2	-0.4	1.4	-0.2	1.1	1.4	-2.1	-1.0	-1.5	-1.4
Arm fat mass (left)	1.2	5.1	9.4	3.1	-0.9	3.0	-2.5	1.6	1.1	2.6	2.6	1.6
Medication: Lisinopril	1.2	1.5	4.8	-0.3	0.3	-2.2	1.4	0.2	-1.4	-1.0	-0.5	-1.8
Leg fat mass (left)	1.2	4.8	9.2	3.0	-0.0	2.9	-2.4	2.1	0.5	2.8	2.5	1.1
Depression (Nagel 2018)	1.1	1.6	3.7	1.3	0.9	-1.1	-1.6	-1.9	-0.1	1.5	1.5	-0.2
Fasting Glucose	1.1	1.4	3.6	1.7	0.1	0.0	-1.9	-1.3	0.8	0.9	0.3	1.6
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	3.4	1.8	1.1	-0.7	-1.7	1.5	-0.5	0.4	0.2	-0.1
Trunk fat mass	1.1	4.8	11.3	3.4	-0.9	2.4	-2.4	0.9	1.0	2.7	2.9	1.4
Hearing difficulty/problems with background noise	1.1	1.7	3.4	1.8	1.4	1.7	-1.8	0.7	0.1	1.5	1.0	0.6
Neuroticism score	1.1	2.3	5.4	2.3	1.9	0.1	-1.7	-1.7	0.1	1.5	1.9	0.0
Impedance of arm (left)	1.1	4.9	15.3	-0.3	2.2	-3.9	0.7	-2.3	-2.6	-1.6	-1.9	-2.3
Medication for pain relief, constipation, heartburn	1.1	1.9	12.1	-0.9	-3.5	0.6	-0.2	0.4	0.6	0.3	-1.0	1.5
Whole body fat mass	1.1	4.6	9.0	3.0	-0.9	2.7	-2.4	1.4	1.0	2.7	2.6	1.4
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	4.1	-1.1	0.0	-0.5	0.8	1.3	-2.0	-0.7	-1.2	-1.4
Handedness (chirality/laterality): Left-handed	1.1	1.3	2.4	0.4	-0.9	1.4	-1.2	1.2	0.9	1.6	1.3	1.1
Guilty feelings	1.1	1.6	4.8	1.2	2.2	0.5	-1.4	-1.6	-0.7	1.1	1.3	-0.8
Ever taken oral contraceptive pill	1.1	1.2	2.6	-1.6	0.7	-1.6	0.9	-1.5	0.6	-1.1	-0.3	-0.3
Alcohol drinker status: Never	1.1	1.4	3.4	-0.3	1.8	-0.2	1.5	0.8	-1.5	-0.7	-0.9	-1.5
Risk taking	1.1	1.6	4.5	-1.6	-0.2	0.4	1.7	-1.5	2.1	-1.1	0.7	0.0
Neuroticism	1.0	2.5	7.8	2.8	2.4	-0.5	-1.4	-1.2	-0.1	1.0	2.0	-0.6
Serious illness, injury or assault to yourself	1.0	1.3	3.6	-1.5	0.3	-0.2	1.7	0.6	-0.2	-1.9	-1.0	-1.1
High blood pressure	1.0	2.7	6.4	2.0	-1.2	0.8	-2.0	1.4	1.2	1.8	2.5	0.8
Medication: Atenolol	1.0	1.2	4.9	1.1	-0.4	0.8	-0.8	-0.5	1.4	1.0	2.2	0.5
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	3.7	1.4	1.9	-1.9	-0.3	-0.7	-1.3	-0.7	0.3	-1.6
Had menopause	1.0	1.3	3.5	0.7	-1.2	1.5	-1.1	-0.1	0.4	1.9	1.4	0.8
Had other major operations	1.0	1.2	4.7	-1.0	-1.1	2.2	0.8	0.6	1.3	-0.4	0.9	-0.0
Forced vital capacity (FVC)	1.0	3.7	9.4	-2.2	-1.4	0.3	3.1	-2.3	2.9	-1.4	0.8	0.4
Medication: Simvastatin	1.0	1.5	3.9	-0.3	0.5	-2.0	1.0	-0.3	-1.9	-0.7	-0.4	-1.9
Forced expiratory volume in 1-second (FEV1)	1.0	3.2	8.1	-2.0	-1.7	1.2	2.6	-1.8	2.9	-1.4	0.4	0.8
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	4.3	-1.6	-1.0	-1.2	1.7	-0.5	-0.5	-1.7	-2.1	-0.4
Forced vital capacity (FVC), Best measure	1.0	3.6	12.0	-2.5	0.1	-0.7	3.5	-2.1	1.9	-2.2	0.3	-0.7
Leg fat mass (right)	1.0	3.9	7.1	2.6	0.2	2.7	-2.1	2.0	0.4	2.5	2.4	0.9
Arm fat percentage (left)	1.0	3.9	8.8	3.0	0.3	2.1	-3.0	1.7	-0.7	2.6	1.4	0.8
Leg fat percentage (left)	1.0	3.6	7.6	2.4	1.5	1.5	-2.2	2.8	-1.9	2.2	1.0	-0.5
Intelligence (Savage-Jansen 2018)	0.9	2.7	9.7	-3.1	-0.0	1.8	2.2	-0.3	2.0	0.4	1.5	0.4
Alzheimer’s Disease (including proxy)	0.9	1.2	3.1	-1.8	-1.2	1.0	1.3	0.4	0.6	-1.3	-1.3	0.3
LDL Cholesterol	0.9	1.4	3.6	1.2	-1.0	1.0	-1.2	0.1	0.7	1.9	1.4	1.1
Neuroticism (2016)	0.9	1.2	3.4	1.8	0.6	-0.6	-1.3	-1.3	0.2	0.7	1.7	-0.1
Hypothyroidism (self reported)	0.9	2.1	4.2	-1.7	0.1	-1.2	1.4	-0.4	-2.0	-1.4	-1.8	-1.7
Relative age of first facial hair	0.9	1.8	5.7	-0.9	1.7	-0.7	0.8	0.2	-2.4	-0.7	-1.6	-1.5
Past tobacco smoking	0.9	1.7	4.0	-0.8	-0.2	-0.7	0.7	1.1	-2.0	-1.6	-2.0	-1.5
Allergy	0.9	2.0	6.5	-0.8	0.5	-2.5	0.4	-1.1	-1.9	-1.1	-0.9	-1.9
Arm fat percentage (right)	0.9	3.5	7.6	2.8	0.2	2.1	-2.8	1.7	-0.7	2.5	1.3	0.9
Alcohol intake versus 10 years previously	0.9	1.3	5.6	-0.1	1.5	-0.6	-0.4	0.6	-2.4	-0.4	-0.9	-1.5
Qualifications: A levels/AS levels or equivalent	0.9	2.0	9.7	-1.4	-1.4	1.2	0.7	-0.7	3.1	-0.7	0.9	1.0
Leg fat percentage (right)	0.9	3.4	7.6	2.0	1.9	1.3	-1.9	2.8	-2.1	1.9	1.0	-0.9
Health satisfaction	0.9	1.2	4.2	1.1	-2.0	0.4	-0.2	-0.9	1.5	0.3	-0.0	1.5
Family relationship satisfaction	0.9	1.1	4.6	0.8	-1.1	-0.9	-0.4	-2.1	1.0	0.2	1.0	0.2
Hypertension (Self-reported)	0.9	2.5	6.3	2.0	-1.2	0.7	-1.7	1.6	1.1	1.7	2.5	0.6
Illnesses of father: Heart disease	0.9	1.3	2.8	-1.1	1.7	-0.3	1.2	-1.1	-0.6	-1.3	-0.4	-1.6
Friendships satisfaction	0.9	1.2	5.7	-1.0	-2.4	0.2	0.7	0.3	1.6	-0.2	0.4	0.6
Financial situation satisfaction	0.9	1.1	2.3	1.2	0.5	0.9	-1.3	0.5	1.0	1.5	1.1	1.0
Number of operations (self-reported)	0.9	1.4	3.6	-0.9	-1.5	1.9	0.9	-0.6	1.6	0.4	1.2	0.3
Schizophrenia vs Biploar Disorder	0.8	1.0	2.9	0.7	0.0	0.6	-1.7	-1.6	0.2	1.3	0.4	1.1
Alzheimer’s Disease (in mother)	0.8	0.9	2.4	-1.5	-0.3	1.6	1.1	0.3	1.3	-0.7	0.0	0.3
Verbal and Numeric Reasoning (VNR)	0.8	1.8	5.4	-2.3	0.1	1.0	2.0	-0.2	2.0	0.1	1.4	0.5
Blood Platelet Count	0.8	9.5	23.1	3.1	-4.4	1.6	-4.8	2.0	1.6	2.3	0.1	4.4
Systolic Blood Pressure	0.8	3.9	13.7	3.7	0.4	-1.6	-3.7	-0.3	-0.0	1.4	1.4	0.6
Angina	0.8	1.0	2.8	1.3	0.3	0.9	-1.3	0.9	-0.6	1.7	0.5	0.8
Trunk fat percentage	0.8	3.2	10.0	3.2	0.2	1.4	-2.6	1.0	-0.8	2.4	1.7	0.4
Medication: Ramipril	0.8	1.0	2.8	1.4	1.0	0.2	-1.1	1.0	-0.2	0.7	1.7	-0.5
Time employed in main current job	0.8	1.0	3.7	1.6	-1.9	-0.3	-0.9	-0.3	0.4	0.4	-0.2	1.1
Mouth/teeth dental problems: Dentures	0.8	1.3	3.6	0.6	1.0	-1.4	1.6	-0.7	-1.3	-0.2	0.4	-1.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	7.7	-2.0	-0.4	0.3	2.8	-1.7	2.1	-1.9	0.3	-0.2
Gout (self-reported)	0.8	1.1	2.9	-0.8	-1.7	1.7	0.0	0.6	1.2	0.7	1.1	0.6
Body fat percentage	0.8	3.3	7.8	2.8	0.6	1.6	-2.5	1.8	-1.1	2.4	1.5	0.2
Angina (self-reported)	0.8	1.0	2.7	1.5	0.2	0.7	-1.3	0.7	-0.6	1.6	0.5	0.7
Leg pain on walking	0.8	1.0	2.7	-1.1	-0.4	-0.3	1.1	-1.2	-0.9	-1.2	-1.7	-0.4
Illnesses of siblings: Diabetes	0.8	1.0	2.8	1.6	-0.8	1.2	-1.7	-0.4	0.4	0.4	0.5	0.9
Mood swings	0.8	1.5	6.2	1.0	2.5	-0.3	-0.3	-1.4	-0.7	0.3	1.2	-1.3
Triglycerides	0.7	1.1	2.2	-0.8	1.4	-1.0	1.3	-0.4	-1.5	-0.4	-0.7	-1.3
Waist Hip Ratio (WHR)	0.7	3.0	6.6	2.6	1.9	-2.3	-0.2	-2.0	-0.9	-0.1	1.2	-2.2
Diabetes (mother)	0.7	0.8	6.3	0.8	-0.0	0.4	-0.5	2.5	-0.3	-0.1	-0.1	-0.2
Maternal smoking around birth	0.7	1.0	4.6	1.2	2.1	-0.4	-0.9	0.1	-0.4	0.6	1.0	-0.5
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.0	-0.5	-0.3	1.0	-0.1	1.2	1.0	0.9	1.4	0.6
Alcohol usually taken with meals	0.7	1.1	6.0	-0.4	-2.4	0.1	-0.4	-0.9	1.1	0.2	0.1	1.3
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	1.9	1.0	1.2	-0.0	-0.6	-1.1	1.3	0.4	1.4	0.5
Impedance of arm (right)	0.7	3.5	12.0	-0.3	1.6	-3.5	0.5	-2.1	-2.1	-1.2	-1.8	-1.6
Worrier / anxious feelings	0.7	1.3	2.5	1.2	-1.0	0.4	-1.6	-1.5	1.1	0.7	1.2	1.1
Number of live births	0.7	0.9	1.6	0.4	-1.2	0.9	-1.2	1.2	0.8	0.9	0.4	1.2
Pulse rate	0.7	1.1	3.9	-0.4	-0.1	1.7	1.2	2.0	0.9	-0.3	0.7	-0.4
Medication: Cholesterol lowering	0.7	1.0	3.7	1.5	1.9	0.4	-0.6	0.2	-0.7	0.8	1.0	-0.6
Depression (self-reported)	0.7	0.8	2.9	1.0	-0.4	-1.3	-0.5	-1.7	0.9	0.1	0.4	0.4
Blood clot in the leg (DVT)	0.7	1.0	2.0	-1.4	-1.3	-0.6	1.0	-1.4	-0.7	-0.3	-1.0	-0.2
Eye problems/disorders: None of the above	0.7	0.9	3.3	1.3	-0.3	-0.5	-0.8	1.8	-1.1	0.4	-0.8	0.0
Long-standing illness, disability or infirmity	0.7	1.1	3.6	-0.7	1.9	0.4	-0.1	1.9	-1.2	0.1	-0.0	-0.9
Irritability	0.7	1.2	3.6	1.9	0.8	0.2	-0.9	-1.5	1.0	0.7	1.4	0.5
Unable to work because of sickness or disability	0.7	0.9	4.1	-0.0	0.2	-1.2	0.2	0.0	-2.0	0.2	-0.3	-1.4
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.2	-1.5	-1.4	-0.5	1.0	-1.1	-0.7	-0.3	-1.0	-0.2
Heart disease (siblings)	0.7	0.8	2.7	0.7	1.2	0.4	-0.4	1.6	-1.4	0.7	-0.3	-0.4
Body Mass Index (BMI) (2010)	0.6	0.8	2.6	0.2	-1.3	1.6	-1.0	-0.0	0.3	0.7	-0.1	1.1
Lupus	0.6	0.9	2.5	-1.6	-0.2	-1.4	0.6	-1.2	-0.7	-0.6	-0.8	-0.5
Schizophrenia (2014)	0.6	1.3	2.8	0.9	1.6	-1.5	0.2	-1.7	-1.2	-0.5	-1.0	-0.9
Hearing difficulty/problems: Yes	0.6	0.9	5.0	0.3	2.2	1.5	-0.7	0.1	-0.1	0.5	0.5	-0.1
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.0	-1.4	-1.2	0.3	0.5	0.9	0.6	-0.8	-0.4	0.5
Medication: Co-codamol	0.6	0.7	2.7	-0.3	1.2	-1.7	0.2	0.1	-0.4	-0.8	-0.0	-1.1
Diabetes (father)	0.6	0.7	2.4	-0.6	-0.8	-1.6	0.6	-0.2	-0.4	-0.9	-1.0	-0.6
Hayfever, allergic rhinitis or eczema	0.6	1.3	3.9	0.8	1.0	2.0	-0.2	0.1	1.8	0.5	1.0	1.2
Pain all over the body in last month	0.6	0.7	1.8	0.3	0.6	-1.1	0.2	-0.5	-1.3	-0.7	-0.5	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.1	-1.0	0.9	0.7	0.7	-1.0	0.3	-1.1	-1.0	-0.0
Lung cancer (father)	0.6	0.7	2.8	1.2	-0.1	-0.5	-1.7	-0.1	-0.4	0.8	0.7	0.3
Tense / ‘highly strung’	0.6	0.9	2.7	1.6	-0.4	-1.6	-0.6	-1.6	0.3	-0.3	0.3	0.1
Loud music exposure frequency	0.6	0.6	1.6	1.0	0.4	0.9	-0.7	-1.3	0.4	0.9	0.7	0.5
Wheeze or whistling in the chest in last year	0.6	1.1	6.5	0.4	1.3	0.0	0.2	2.5	-1.1	0.2	-0.0	-0.8
Neck or shoulder pain in last month	0.6	0.8	3.2	1.2	1.8	0.0	-0.6	0.9	-0.9	0.3	0.6	-0.8
Medication: Blood pressure	0.6	1.1	4.0	1.1	0.8	-0.2	-1.3	-0.5	1.0	0.9	2.0	0.1
Loneliness, isolation	0.6	0.9	3.0	0.3	1.6	-0.6	0.7	0.2	-0.9	-0.7	0.4	-1.7
Diabetes diagnosed by doctor	0.6	1.0	3.4	0.6	0.7	-1.8	-0.2	-0.5	-1.6	-0.5	-0.0	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.7	-0.9	-0.2	0.0	1.1	0.8	-0.3	-1.3	-0.5	-1.3
Breast cancer (self-reported)	0.6	0.8	2.9	0.9	-1.3	1.0	-0.3	1.7	0.1	0.5	0.2	0.3
Osteoporosis (self-reported)	0.6	0.8	3.5	-0.5	1.2	0.4	-0.4	1.9	-0.1	0.8	-0.0	0.8
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.0	-0.6	-1.4	-0.2	-0.7	-0.3	1.1	1.1	0.9	1.1
High cholesterol (Self-reported)	0.6	1.0	2.0	1.2	1.4	0.3	0.2	1.1	-1.0	0.9	1.2	-1.0
Ever had prostate specific antigen (PSA) test	0.6	0.6	2.8	-0.3	-1.7	-0.1	-0.7	-1.1	0.5	0.6	0.1	0.7
Myopia	0.6	0.9	6.1	-1.0	-0.1	0.2	0.7	2.5	0.6	-0.2	0.1	-0.1
Vascular/heart problems diagnosed by doctor	0.6	1.7	4.1	-1.7	0.8	-0.4	1.7	-1.4	-0.5	-1.5	-2.0	-0.4
Irritable Bowel Disease (IBD)	0.5	1.1	2.2	-0.8	0.3	-0.4	1.0	-1.5	-1.1	-1.3	-1.4	-1.1
Age at First Birth	0.5	0.7	1.9	0.8	0.9	-0.5	-1.3	0.0	-0.9	1.4	0.7	-0.0
Smoking Status	0.5	1.1	3.1	0.7	1.7	1.5	-0.0	0.7	0.8	1.1	1.5	0.2
Allergy or Eczema	0.5	1.3	4.9	0.6	0.5	2.2	0.0	0.7	1.9	0.5	0.8	1.2
Cardiovascular Disease	0.5	1.7	5.7	2.4	-0.7	-0.0	-1.1	2.1	-0.0	1.2	1.4	-0.1
Average weekly spirits intake	0.5	0.6	1.7	-0.5	-1.2	0.8	1.3	-0.7	0.7	0.3	0.5	0.2
Vitamin and mineral supplements	0.5	0.7	2.4	-0.9	0.1	-0.1	-0.3	1.2	-1.5	-0.1	-0.4	-1.0
Medication: Metformin	0.5	0.8	3.9	0.4	0.2	-0.1	-1.1	2.0	-0.8	0.6	0.5	-0.3
Hand grip strength (right)	0.5	1.2	4.1	1.5	0.2	0.8	-0.3	0.3	2.0	0.5	1.1	1.5
Taking other prescription medications	0.5	0.7	3.7	0.5	0.9	0.3	-0.1	1.9	-0.7	-0.1	0.6	-0.8
Multivitamins +/- minerals	0.5	0.6	2.2	0.7	-0.8	-0.1	-0.0	-0.6	1.5	0.5	0.5	1.1
High blood pressure (mother)	0.5	0.7	1.6	-0.2	1.1	-1.3	0.7	-0.8	-0.1	-1.2	-0.4	-0.9
Nervous feelings	0.5	0.9	4.5	2.1	0.4	-0.9	-1.1	-0.9	-0.5	0.0	0.2	0.0
Hair/balding pattern: Pattern 2	0.5	0.6	1.5	0.9	-0.8	-0.0	-0.8	-0.9	0.9	0.8	0.1	1.2
Length of working week for main job	0.5	0.5	3.7	0.3	0.0	-0.5	-0.1	-1.9	0.1	0.6	0.4	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	4.9	2.2	-0.8	0.3	-0.6	0.2	0.8	0.0	0.6	0.6
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.1	0.9	0.7	0.8	-0.7	0.2	1.0	0.9	1.1	0.7
High blood pressure (siblings)	0.5	0.7	2.0	0.8	0.7	-0.6	-0.0	-0.4	-1.4	-0.9	-0.5	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	2.1	-1.5	-0.1	1.0	1.1	-0.4	0.7	-0.1	0.0	0.4
Mouth/teeth dental problems: Loose teeth	0.5	0.5	1.1	-0.4	1.0	0.5	0.7	-1.0	0.2	0.1	1.0	-0.9
Overall health rating	0.5	1.1	5.4	2.3	-0.1	-0.4	-1.1	1.3	-0.7	0.6	0.5	-0.2
Eye problems/disorders: Cataract	0.5	0.6	2.1	0.9	0.8	0.4	-0.7	-0.4	0.5	0.9	1.4	0.3
Medication: Blood pressure	0.5	0.9	2.8	1.1	-0.3	-0.1	-0.2	1.5	-0.8	-0.3	1.0	-1.7
Average weekly beer plus cider intake	0.5	0.7	2.1	1.5	1.1	-0.1	-1.4	0.6	-0.3	0.4	0.1	0.0
Pain experienced in last month	0.5	0.8	4.2	-0.6	0.1	-0.7	1.2	-2.1	0.1	-0.4	-0.3	-0.3
Bipolar Disorder or Schizophrenia	0.4	0.9	2.7	1.5	1.6	-0.6	-0.4	-1.5	-0.1	0.1	0.2	-0.2
Schizophrenia (2018)	0.4	0.9	3.2	1.0	1.8	-1.0	-0.3	-1.5	-0.3	0.2	-0.3	-0.1
Crohns Disease (2017)	0.4	0.9	2.8	-0.1	0.5	-0.0	0.8	-0.6	-1.7	-0.8	-1.0	-1.4
Number of treatments/medications taken	0.4	0.8	1.8	1.1	1.4	-0.7	0.2	-1.1	-0.0	-0.6	0.7	-1.1
Ever had hysterectomy (womb removed)	0.4	0.5	1.5	-0.9	0.7	-0.4	0.4	-0.1	-0.8	-0.4	0.4	-1.2
Pack years adult smoking proportion	0.4	0.7	3.8	-0.1	0.3	-0.3	0.1	-0.7	-2.0	0.3	-0.8	-0.9
Stomach or abdominal pain in last month	0.4	0.5	2.6	-0.2	-1.0	0.1	0.3	1.6	0.4	-0.8	-0.6	0.1
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.1	0.9	0.8	-0.8	-0.6	0.4	-1.1	0.3	-0.2	-0.4
Mouth/teeth dental problems	0.4	0.7	2.8	-1.2	-0.6	-0.0	-0.5	-0.1	-0.6	-0.8	-1.7	0.5
Diabetes (self-reported)	0.4	0.6	1.1	1.0	0.7	-1.1	-0.7	0.0	-1.0	0.2	0.7	-0.9
Father’s age at death	0.4	0.5	1.5	-0.7	-1.2	0.5	-0.7	-0.2	0.1	0.2	-0.4	1.1
Happiness	0.4	0.5	1.1	1.1	-0.7	-0.8	-0.4	-0.7	0.5	0.3	0.9	-0.2
Noisy workplace	0.4	0.6	1.5	1.2	-0.7	-0.5	-1.2	0.5	0.2	0.6	0.6	0.6
Medication: Allopurinol	0.4	0.6	2.2	-0.8	-1.5	0.8	0.6	0.2	1.0	-0.1	0.4	0.3
Medication: Omeprazole	0.4	0.5	1.3	0.7	0.9	-0.6	0.7	0.2	-0.7	-0.6	-0.2	-1.1
Pulse rate, automated reading	0.4	1.2	3.7	0.7	0.6	1.9	0.8	1.1	1.4	-0.4	1.6	-0.4
Medication for cholesterol	0.4	0.6	1.4	-0.8	0.8	0.3	-0.4	-1.2	0.7	-0.2	-1.0	1.2
Illnesses of father: None of the above (group 1)	0.4	0.5	1.3	1.1	0.9	0.3	-0.7	0.5	-0.9	0.9	0.3	-0.4
Medication: Atorvastatin	0.4	0.5	1.0	0.8	1.0	1.0	-0.5	-0.7	0.2	0.5	1.0	-0.0
Illnesses of father: High blood pressure	0.4	0.5	2.6	0.4	0.5	-1.6	-0.0	-0.0	-0.5	-0.6	-0.3	-0.7
Ever smoked	0.4	0.8	1.6	-0.3	0.6	0.8	-0.3	-0.9	1.2	1.0	0.9	1.3
Diastolic blood pressure, automated reading	0.4	1.3	3.2	1.3	0.5	1.1	-1.8	1.1	0.6	1.0	1.6	0.2
Supplements: Calcium	0.4	0.5	1.5	0.7	0.6	1.0	0.3	-1.2	0.9	-0.0	0.2	0.5
Ulcerative Colitis (UC)	0.3	0.5	1.3	-1.1	-0.4	0.0	0.6	-1.2	0.4	-0.7	-0.8	0.1
Major Depression (MDD)	0.3	0.4	1.0	1.0	0.4	0.5	-0.8	0.3	0.4	0.7	0.8	0.3
Bipolar Disorder (2011)	0.3	0.3	1.1	0.3	0.5	-0.1	0.3	-0.5	0.6	0.1	1.1	-0.4
Coronary Artery Disease (CAD)	0.3	0.4	1.5	0.2	0.4	-0.6	-0.2	0.6	-1.2	0.1	-1.1	-0.2
Ulcerative Colitis	0.3	0.4	2.5	-0.4	0.0	-0.2	0.3	-1.6	1.0	-0.4	0.3	0.2
Lung FEV1/FVC ratio	0.3	1.4	4.6	0.1	-2.1	2.1	-0.6	-1.0	1.2	0.0	0.1	1.0
Hand grip strength (left)	0.3	0.8	2.5	1.6	-0.4	0.5	-0.0	0.2	1.5	0.2	0.6	1.2
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.7	-1.3	-0.7	-0.1	1.2	0.4	0.4	-0.1	0.0	-0.1
Medication: Levothyroxine sodium	0.3	0.6	1.7	0.8	-0.3	1.3	-0.5	0.7	0.3	0.8	1.1	0.2
Financial difficulties in last 2 years	0.3	0.4	1.3	0.7	1.1	-0.0	-0.2	1.1	-0.3	-0.0	-0.5	-0.0
Falls in the last year	0.3	0.4	1.3	-0.3	-0.7	1.1	-0.5	1.0	-0.2	0.2	0.1	0.1
Prospective memory result	0.3	0.3	1.1	0.5	0.1	0.3	-0.9	0.4	-1.0	0.0	-0.2	-0.7
Illnesses of mother	0.3	0.3	1.2	-0.3	-0.6	-0.2	-0.1	0.1	-1.1	1.1	-0.2	0.1
Hair/balding pattern: Pattern 4	0.3	0.8	2.3	0.3	0.5	0.4	-1.5	-1.4	-0.1	1.2	0.5	0.5
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.1	0.6	-0.7	0.8	-0.4	1.1	-0.6	0.5	0.0	0.0
Glaucoma (self-reported)	0.3	0.3	0.7	-0.3	0.8	0.4	0.1	-0.8	0.8	0.4	0.6	0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.9	-1.4	0.2	-0.2	0.7	-0.1	-1.2	-0.3	-0.5	-1.0
Number of children fathered	0.3	0.3	1.1	0.8	1.1	-0.7	-0.4	0.0	0.5	0.3	0.6	0.1
Migraine (self-reported)	0.3	0.3	2.1	-0.5	1.4	0.1	-0.3	0.2	-0.1	0.3	-0.3	0.5
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.7	-0.4	-0.2	-0.1	0.6	1.3	-0.4	-0.4	-0.2	-0.3
Medication: Aspirin	0.3	0.4	1.0	1.0	0.9	-0.8	-0.3	-0.2	-0.8	0.2	0.2	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.8	-1.1	0.2	-0.2	1.3	-0.4	0.3	-0.1	0.3	-0.3
Back pain experienced in last month	0.3	0.5	2.2	0.8	1.5	0.3	-0.8	0.4	-0.8	0.4	-0.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	1.9	-1.2	-0.1	0.9	0.3	-0.1	1.4	-0.6	0.4	0.4
Number of self-reported non-cancer illnesses	0.3	0.6	1.8	0.8	-0.2	1.0	-0.6	0.0	1.1	0.6	1.3	0.5
Commuting to job workplace: Public transport	0.3	0.3	0.6	-0.8	0.0	0.6	0.1	0.5	-0.7	-0.5	-0.6	-0.7
Eye problems/disorders: Glaucoma	0.3	0.4	1.2	-0.5	1.1	-0.3	0.4	-1.0	0.5	0.2	0.5	0.1
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.7	0.1	0.6	0.9	0.0	1.3	-0.2	-0.1	0.3	-0.5
Alcohol drinker status: Previous	0.3	0.4	1.2	0.8	1.1	0.4	-0.0	0.7	-0.7	0.1	-0.3	-0.4
Pack years of smoking	0.3	0.5	2.4	0.1	-0.2	0.2	-0.3	-1.0	-1.5	0.9	-0.2	-0.4
Bipolar Disorder (2018)	0.2	0.3	1.3	1.2	0.4	0.4	-0.4	-0.5	0.3	-0.1	0.7	-0.3
Breast Cancer	0.2	0.4	1.8	0.5	0.9	0.7	0.0	0.2	-1.3	0.3	-0.3	-0.7
Ovarian Cancer	0.2	0.3	1.2	0.6	-0.3	0.4	0.1	0.2	0.7	0.4	1.1	0.1
Crohns Disease (2012)	0.2	0.3	1.3	-0.1	0.3	1.0	0.5	-1.1	-0.1	-0.2	0.1	-0.6
Primary Biliary Cirrhosis	0.2	0.3	0.8	-0.5	0.3	-0.1	0.1	-0.7	-0.2	-0.9	-0.8	-0.0
Rheumatoid Arthritis	0.2	0.2	0.9	-0.4	-0.5	-0.5	0.7	-1.0	0.0	0.0	-0.2	-0.0
Blood Eosinophil Count	0.2	1.9	12.4	1.9	-0.9	-0.0	-0.4	3.5	-0.0	0.2	-0.1	0.2
Heel T-Score	0.2	1.3	4.0	-1.1	-0.6	-1.4	0.4	-2.0	0.4	-1.4	-1.5	0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.1	0.4	-0.0	-1.0	-0.5	-0.3	-1.0	-0.4	-0.4	-0.7
Hair Pigment	0.2	6.7	13.1	-1.4	3.0	-2.7	1.8	-0.1	-3.6	-2.4	-3.2	-3.0
Tanning	0.2	2.1	6.0	1.0	0.3	1.0	-2.4	1.6	-0.8	2.4	1.1	0.8
Medication for hormone replacement therapy	0.2	0.2	0.8	0.3	-0.2	0.9	0.5	-0.6	-0.0	0.6	0.4	0.1
Townsend deprivation index at recruitment	0.2	0.3	1.5	1.2	0.4	-0.2	0.4	0.1	-0.3	0.2	0.5	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.3	0.3	-0.3	-0.2	-0.6	-1.1	0.5	1.0	0.6	0.9
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.7	0.0	-0.4	0.6	-0.4	0.6	0.3	0.3	0.8	-0.1
Chronic bronchitis/emphysema (father)	0.2	0.2	0.7	-0.3	-0.8	0.4	0.3	0.6	0.2	0.0	-0.4	0.6
Exposure to tobacco smoke at home	0.2	0.2	0.6	0.3	0.8	-0.3	-0.1	0.2	-0.6	-0.5	-0.4	-0.4
Breastfed as a baby	0.2	0.3	1.3	0.6	-0.3	-1.2	-0.1	0.2	0.1	-0.7	-0.3	-0.1
Birth weight of first child	0.2	0.4	1.3	-0.3	0.3	-0.7	1.1	0.2	-0.0	-1.1	-0.4	-0.6
Headache pain in last month	0.2	0.4	1.8	0.4	1.3	-0.3	-0.2	0.5	-0.5	-0.1	0.5	-0.9
Medication: Amlodipine	0.2	0.3	1.2	0.3	0.3	-0.5	-0.0	-0.5	0.4	-0.2	1.1	-0.6
Number of full brothers	0.2	0.3	0.8	-0.2	-0.5	0.8	-0.2	0.3	-0.5	-0.7	-0.9	-0.3
Heart disease (mother)	0.2	0.3	1.5	0.3	-0.1	1.2	-0.8	0.2	0.5	-0.1	0.3	0.3
Chest pain or discomfort	0.2	0.3	0.5	0.0	0.6	0.6	0.6	0.7	-0.5	-0.6	-0.3	-0.6
Medication: Aspirin	0.2	0.2	1.2	1.1	0.3	-0.5	-0.2	0.1	-0.5	0.3	0.3	-0.2
Medication: Gliclazide	0.2	0.2	0.9	0.4	0.5	-1.0	-0.4	-0.1	-0.4	-0.5	-0.2	-0.5
Ever depressed for a whole week	0.2	0.3	1.2	0.2	0.5	-1.1	-0.2	-0.3	-0.1	-0.6	-0.7	-0.0
Cholesterol lowering medication	0.2	0.3	1.8	-0.3	-1.3	-0.0	0.6	0.2	0.2	-0.0	0.5	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.3	1.1	0.7	-0.2	0.1	-0.3	-0.5	-0.2	0.0	-0.7
Basal cell carcinoma (self-reported)	0.2	0.2	1.0	-0.4	0.2	-0.4	-0.1	0.4	-1.0	0.1	-0.5	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	1.6	0.2	0.6	-1.2	-0.1	-0.1	0.1	0.2	0.3	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.3	0.2	-0.3	0.2	-0.6	-0.2	0.4	0.3	0.6	0.4
Hearing aid user	0.1	0.2	0.3	0.3	0.4	0.6	0.5	0.6	-0.0	0.3	0.2	-0.3
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.6	0.8	0.1	0.1	0.4	0.5	-0.5	0.1	-0.2	-0.2

Hub : Genes

FKBP1B

Models

Trait associations