[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr17:60,821,100-64,251,733

Best TWAS P=5.06e-46 · Best GWAS P=4.05e-44 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Adipose Subcutaneous	CD79B	0.15	0.16	enet	9	0.17	3.5e-14	-13.4	14.2	5.1e-46	0.50	0.04	0.96	TRUE
2	CommonMind	Brain Pre-frontal Cortex	SMARCD2	0.03	0.03	blup	330	0.03	1.1e-04	13.9	10.1	3.4e-24	0.86	0.01	0.98	TRUE
64	YFS	Blood	SMARCD2	0.03	0.04	lasso	7	0.05	7.6e-15	13.3	10.1	8.4e-24	0.88	0.64	0.36	TRUE
26	GTEx	Colon Transverse	DDX42	0.19	0.07	lasso	4	0.11	4.4e-06	-2.6	-7.7	2.0e-14	-0.70	0.21	0.73	TRUE
38	GTEx	Muscle Skeletal	PSMC5	0.04	0.02	lasso	2	0.02	3.1e-03	9.6	7.4	1.7e-13	0.70	0.48	0.06	TRUE
68	The Cancer Genome Atlas	Colon Adenocarcinoma	DDX42	0.04	0.01	blup	51	0.02	1.6e-02	-2.1	-6.0	1.6e-09	-0.66	0.06	0.38	TRUE
61	YFS	Blood	AXIN2	0.20	0.05	enet	34	0.10	5.1e-31	5.1	-5.9	3.6e-09	0.00	1.00	0.00	TRUE
34	GTEx	Heart Atrial Appendage	CYB561	0.19	0.01	enet	28	0.06	1.3e-03	2.1	5.4	5.7e-08	0.41	0.05	0.32	TRUE
67	The Cancer Genome Atlas	Breast Invasive Carcinoma	SCN4A	0.04	0.01	blup	39	0.03	1.4e-07	-13.8	-13.6	5.4e-42	-0.33	0.03	0.95	FALSE
65	The Cancer Genome Atlas	Breast Invasive Carcinoma	CD79B	0.02	0.02	lasso	2	0.01	3.0e-03	-13.8	13.4	3.6e-41	0.37	0.02	0.59	FALSE
60	NTR	Blood	MAP3K3	0.02	0.01	lasso	2	0.01	2.0e-04	13.3	-13.3	2.0e-40	-0.89	0.45	0.55	FALSE
10	GTEx	Artery Tibial	MAP3K3	0.05	0.07	lasso	5	0.07	2.9e-06	13.3	13.3	2.2e-40	0.94	0.11	0.87	FALSE
53	GTEx	Testis	PSMC5	0.14	0.13	lasso	6	0.14	6.0e-07	13.3	-13.0	2.2e-38	-0.91	0.19	0.80	FALSE
46	GTEx	Skin Not Sun Exposed Suprapubic	MAP3K3	0.12	0.13	enet	10	0.15	1.8e-08	12.7	12.9	5.8e-38	0.92	0.14	0.86	FALSE
32	GTEx	Esophagus Muscularis	DCAF7	0.08	0.06	lasso	7	0.05	6.7e-04	12.8	12.8	1.6e-37	0.90	0.16	0.77	FALSE
16	GTEx	Breast Mammary Tissue	MAP3K3	0.10	0.11	lasso	8	0.08	8.9e-05	12.7	12.8	2.0e-37	0.91	0.32	0.66	FALSE
21	GTEx	Cells EBV-transformed lymphocytes	DDX42	0.11	0.14	lasso	2	0.12	1.3e-04	12.7	-12.7	9.3e-37	-0.91	0.20	0.41	FALSE
40	GTEx	Nerve Tibial	MAP3K3	0.07	0.10	lasso	2	0.08	4.1e-06	12.7	12.7	1.1e-36	0.90	0.60	0.38	FALSE
20	GTEx	Breast Mammary Tissue (Female)	MAP3K3	0.07	0.01	lasso	1	0.00	4.1e-01	12.6	12.6	1.5e-36	0.90	0.05	0.17	FALSE
51	GTEx	Spleen	MAP3K3	0.21	0.14	lasso	10	0.10	1.4e-03	12.7	12.5	4.9e-36	0.89	0.25	0.49	FALSE
48	GTEx	Skin Sun Exposed Lower leg	MAP3K3	0.08	0.08	lasso	3	0.08	6.8e-07	12.7	12.5	8.3e-36	0.90	0.88	0.09	FALSE
37	GTEx	Lung	MAP3K3	0.07	0.07	lasso	2	0.06	2.8e-05	12.3	12.4	3.6e-35	0.89	0.39	0.58	FALSE
4	GTEx	Adipose Subcutaneous	MAP3K3	0.09	0.07	lasso	6	0.07	3.5e-06	12.7	12.4	4.4e-35	0.91	0.78	0.22	FALSE
44	GTEx	Pituitary	MAP3K3	0.11	0.07	lasso	6	0.04	3.5e-02	12.6	12.1	1.2e-33	0.89	0.04	0.71	FALSE
13	GTEx	Brain Nucleus accumbens basal ganglia	DDX42	0.23	0.04	lasso	12	0.07	8.1e-03	12.7	-12.0	2.6e-33	-0.75	0.09	0.56	FALSE
77	The Cancer Genome Atlas	Brain Lower Grade Glioma	SMARCD2	0.08	0.04	blup	28	0.04	5.1e-05	13.3	12.0	4.3e-33	0.92	0.00	1.00	FALSE
84	The Cancer Genome Atlas	Thyroid Carcinoma	MAP3K3	0.02	0.02	blup	52	0.01	1.4e-02	12.3	12.0	5.7e-33	0.89	0.02	0.74	FALSE
5	GTEx	Adipose Visceral Omentum	CD79B	0.15	0.00	lasso	6	0.02	4.1e-02	-13.4	11.9	9.7e-33	0.32	0.10	0.28	FALSE
19	GTEx	Breast Mammary Tissue (Female)	DCAF7	0.10	0.02	lasso	3	0.00	4.4e-01	11.2	11.8	4.3e-32	0.85	0.06	0.23	FALSE
12	GTEx	Brain Hypothalamus	DDX42	0.15	0.18	lasso	3	0.09	4.2e-03	13.9	-11.6	4.2e-31	-0.97	0.01	0.92	FALSE
47	GTEx	Skin Sun Exposed Lower leg	DDX42	0.07	0.04	lasso	4	0.05	2.5e-05	13.3	-11.5	1.1e-30	-0.92	0.12	0.88	FALSE
63	YFS	Blood	LIMD2	0.03	0.03	enet	11	0.03	3.6e-11	11.2	-11.5	1.9e-30	-0.77	0.91	0.09	FALSE
79	The Cancer Genome Atlas	Lung Adenocarcinoma	SMARCD2	0.04	0.02	blup	28	0.01	1.6e-02	12.7	11.5	1.9e-30	0.90	0.00	0.78	FALSE
42	GTEx	Pancreas	DDX42	0.17	0.18	lasso	3	0.16	3.6e-07	12.6	-11.1	1.5e-28	-0.88	0.81	0.18	FALSE
28	GTEx	Esophagus Mucosa	DDX42	0.08	0.06	lasso	3	0.09	1.3e-06	12.7	-11.1	1.6e-28	-0.87	0.33	0.65	FALSE
6	GTEx	Adipose Visceral Omentum	MAP3K3	0.10	0.04	enet	12	0.05	9.0e-04	12.7	10.9	6.8e-28	0.78	0.08	0.76	FALSE
1	CommonMind	Brain Pre-frontal Cortex	KCNH6	0.04	0.02	enet	9	0.04	1.4e-05	12.7	10.9	1.1e-27	0.77	0.03	0.96	FALSE
59	NTR	Blood	LIMD2	0.04	0.03	blup	304	0.03	2.2e-10	13.3	-10.6	3.5e-26	-0.78	0.35	0.65	FALSE
18	GTEx	Breast Mammary Tissue (Female)	CD79B	0.04	0.07	lasso	2	0.03	4.2e-02	-10.9	10.5	1.0e-25	0.37	0.04	0.15	FALSE
9	GTEx	Artery Tibial	DDX42	0.13	0.14	lasso	5	0.15	9.1e-12	12.7	-10.5	1.2e-25	-0.85	0.31	0.69	FALSE
43	GTEx	Pancreas	MAP3K3	0.10	0.08	lasso	4	0.07	9.0e-04	12.7	10.5	1.3e-25	0.81	0.07	0.58	FALSE
81	The Cancer Genome Atlas	Prostate Adenocarcinoma	DDX42	0.07	0.07	enet	11	0.07	9.2e-08	12.7	-10.5	1.4e-25	-0.86	0.19	0.81	FALSE
82	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMC5	0.04	0.03	lasso	1	0.03	5.6e-04	-10.4	-10.4	1.5e-25	-0.39	0.16	0.03	FALSE
29	GTEx	Esophagus Mucosa	MAP3K3	0.05	0.01	enet	11	0.02	1.8e-02	9.6	10.3	5.5e-25	0.78	0.03	0.91	FALSE
17	GTEx	Breast Mammary Tissue (Male)	MAP3K3	0.12	0.14	lasso	2	0.07	1.2e-02	12.3	9.8	9.0e-23	0.86	0.05	0.70	FALSE
71	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STRADA	0.05	0.03	lasso	1	0.02	1.7e-03	-9.8	-9.8	1.1e-22	-0.39	0.04	0.07	FALSE
56	GTEx	Whole Blood	CCDC47	0.05	0.00	lasso	5	0.01	9.8e-02	1.3	-9.7	3.5e-22	-0.66	0.03	0.64	FALSE
31	GTEx	Esophagus Muscularis	PSMC5	0.12	0.08	lasso	3	0.07	3.8e-05	-10.6	-9.6	7.1e-22	-0.32	0.52	0.04	FALSE
30	GTEx	Esophagus Mucosa	STRADA	0.05	0.07	lasso	2	0.05	1.9e-04	-9.7	-9.6	1.0e-21	-0.39	0.30	0.06	FALSE
72	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DDX42	0.04	0.02	blup	51	0.03	3.9e-04	13.3	-9.5	2.7e-21	-0.84	0.01	0.97	FALSE
33	GTEx	Esophagus Muscularis	MAP3K3	0.07	0.02	enet	8	0.02	3.0e-02	12.7	9.3	1.6e-20	0.80	0.30	0.44	FALSE
25	GTEx	Colon Sigmoid	CD79B	0.17	0.00	lasso	9	0.08	9.7e-04	12.6	9.1	8.5e-20	0.62	0.05	0.47	FALSE
23	GTEx	Cells Transformed fibroblasts	PSMC5	0.19	0.09	lasso	5	0.10	7.1e-08	-9.8	-8.9	3.9e-19	-0.38	0.88	0.09	FALSE
50	GTEx	Spleen	FTSJ3	0.19	0.07	lasso	3	0.06	1.2e-02	11.3	8.9	7.2e-19	0.79	0.27	0.31	FALSE
52	GTEx	Stomach	DCAF7	0.24	0.00	enet	33	0.08	1.2e-04	3.2	8.9	7.2e-19	0.37	0.03	0.65	FALSE
73	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SCN4A	0.05	0.01	blup	41	0.04	2.2e-05	4.7	-8.8	1.9e-18	0.08	0.12	0.49	FALSE
78	The Cancer Genome Atlas	Brain Lower Grade Glioma	STRADA	0.03	0.00	blup	57	0.01	5.2e-02	-9.8	8.5	1.7e-17	0.23	0.03	0.04	FALSE
76	The Cancer Genome Atlas	Brain Lower Grade Glioma	DDX42	0.06	0.04	blup	51	0.06	7.9e-08	-2.1	-8.2	2.0e-16	-0.76	0.08	0.92	FALSE
83	The Cancer Genome Atlas	Stomach Adenocarcinoma	DDX42	0.04	0.02	blup	51	0.04	5.2e-04	12.7	-8.2	3.4e-16	-0.77	0.02	0.80	FALSE
15	GTEx	Breast Mammary Tissue	DCAF7	0.08	0.00	enet	18	0.05	1.1e-03	9.5	7.9	2.9e-15	0.52	0.07	0.33	FALSE
85	The Cancer Genome Atlas	Thyroid Carcinoma	SCN4A	0.04	0.01	blup	41	0.02	5.7e-03	4.7	-7.8	7.5e-15	-0.23	0.02	0.04	FALSE
75	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PSMC5	0.13	0.06	blup	27	0.07	7.2e-05	-2.1	7.4	1.3e-13	0.74	0.26	0.36	FALSE
39	GTEx	Muscle Skeletal	SMARCD2	0.13	0.03	lasso	5	0.04	1.3e-04	-9.8	-7.3	2.8e-13	-0.20	0.84	0.01	FALSE
57	METSIM	Adipose	CD79B	0.04	0.01	lasso	5	0.01	4.3e-03	-4.2	7.2	4.1e-13	0.40	0.15	0.47	FALSE
62	YFS	Blood	ICAM2	0.06	0.03	enet	21	0.04	1.3e-11	3.9	-7.1	1.1e-12	-0.11	1.00	0.00	FALSE
8	GTEx	Artery Aorta	CCDC47	0.08	0.02	lasso	2	0.01	9.4e-02	-2.1	7.0	1.8e-12	0.73	0.06	0.65	FALSE
14	GTEx	Brain Putamen basal ganglia	DDX42	0.16	0.04	lasso	4	0.06	1.5e-02	-3.5	-7.0	2.0e-12	-0.49	0.09	0.28	FALSE
74	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	STRADA	0.07	0.01	blup	57	0.03	5.5e-04	1.2	7.0	2.6e-12	0.13	0.10	0.03	FALSE
41	GTEx	Pancreas	FTSJ3	0.19	0.28	enet	44	0.31	1.7e-13	-2.1	7.0	3.4e-12	0.72	0.98	0.02	FALSE
45	GTEx	Skin Not Sun Exposed Suprapubic	DDX42	0.17	0.10	lasso	9	0.10	2.4e-06	-2.1	-6.9	4.7e-12	-0.72	0.29	0.71	FALSE
69	The Cancer Genome Atlas	Colon Adenocarcinoma	FTSJ3	0.16	0.17	blup	30	0.18	1.9e-10	-2.1	6.8	7.6e-12	0.73	0.70	0.30	FALSE
36	GTEx	Lung	DDX42	0.06	0.04	enet	7	0.04	5.8e-04	-2.1	-6.7	1.9e-11	-0.73	0.45	0.45	FALSE
27	GTEx	Esophagus Mucosa	CCDC47	0.12	0.00	lasso	5	0.00	3.7e-01	12.7	6.7	2.0e-11	0.65	0.07	0.34	FALSE
54	GTEx	Testis	CCDC47	0.17	0.06	enet	28	0.09	1.0e-04	-10.4	6.6	4.8e-11	0.13	0.16	0.73	FALSE
35	GTEx	Lung	TEX2	0.04	0.02	enet	13	0.01	5.0e-02	2.5	6.5	5.8e-11	0.48	0.13	0.17	FALSE
80	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FTSJ3	0.13	0.13	blup	30	0.13	5.0e-15	-2.1	6.5	9.6e-11	0.71	0.99	0.01	FALSE
49	GTEx	Small Intestine Terminal Ileum	FTSJ3	0.29	0.23	enet	50	0.22	1.3e-05	-2.1	6.1	1.3e-09	0.62	0.55	0.35	FALSE
55	GTEx	Testis	TEX2	0.22	0.03	enet	17	0.06	1.3e-03	1.9	6.0	1.5e-09	0.22	0.26	0.05	FALSE
58	METSIM	Adipose	RP11-214C8.2	0.03	0.00	blup	304	0.01	4.2e-03	-3.0	-6.0	2.1e-09	-0.14	0.25	0.03	FALSE
11	GTEx	Brain Cerebellum	DDX42	0.12	0.00	enet	19	0.02	7.0e-02	-1.7	-5.7	1.0e-08	-0.66	0.10	0.17	FALSE
70	The Cancer Genome Atlas	Glioblastoma Multiforme	FTSJ3	0.25	0.22	blup	30	0.24	8.7e-08	-1.7	5.7	1.0e-08	0.68	0.17	0.80	FALSE
7	GTEx	Adrenal Gland	FTSJ3	0.16	0.16	lasso	4	0.20	9.3e-08	-2.1	5.7	1.1e-08	0.73	0.30	0.68	FALSE
66	The Cancer Genome Atlas	Breast Invasive Carcinoma	FTSJ3	0.07	0.09	blup	30	0.10	1.6e-19	-2.1	5.6	1.8e-08	0.68	1.00	0.00	FALSE
22	GTEx	Cells Transformed fibroblasts	CD79B	0.20	0.00	lasso	4	0.00	4.3e-01	-1.1	-5.6	2.7e-08	-0.12	0.10	0.16	FALSE
24	GTEx	Cells Transformed fibroblasts	ICAM2	0.17	0.06	lasso	5	0.09	5.6e-07	3.7	-5.4	5.7e-08	-0.09	0.94	0.00	FALSE