[Hub]/) : Traits : Sitting height : ← →

chr19:48,464,978-51,224,297

Best TWAS P=3e-16 · Best GWAS P=2.77e-12 conditioned to 0.191

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MED25	0.05	0.01	blup	361	0.02	2.2e-03	-4.9	-5.2	1.6e-07	0.06	0.22	0.03	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PNKP	0.15	0.16	enet	23	0.16	7.0e-19	-5.0	-5.6	2.1e-08	0.02	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	PRR12	0.11	0.10	lasso	1	0.09	1.0e-07	7.0	7.0	3.6e-12	0.99	0.00	1.00	FALSE
4	GTEx	Adrenal Gland	RASIP1	0.20	0.11	lasso	4	0.10	2.4e-04	5.2	-5.5	3.6e-08	-0.01	0.04	0.92	FALSE
5	GTEx	Artery Aorta	PRR12	0.21	0.13	lasso	5	0.15	7.6e-09	4.4	5.7	1.3e-08	0.95	0.01	0.99	FALSE
6	GTEx	Brain Cerebellar Hemisphere	PRR12	0.27	0.12	lasso	5	0.10	2.0e-03	6.9	7.3	2.1e-13	0.96	0.01	0.87	FALSE
7	GTEx	Brain Cerebellar Hemisphere	AP2A1	0.33	0.05	lasso	7	0.06	1.1e-02	3.4	-5.4	6.7e-08	-0.26	0.06	0.30	FALSE
8	GTEx	Brain Cerebellum	PRR12	0.36	0.33	lasso	6	0.31	6.8e-10	6.9	7.3	2.5e-13	0.98	0.00	1.00	FALSE
9	GTEx	Breast Mammary Tissue	PRR12	0.23	0.09	lasso	6	0.11	3.3e-06	4.8	6.5	1.1e-10	0.75	0.02	0.98	FALSE
10	GTEx	Breast Mammary Tissue (Male)	PRR12	0.41	0.29	lasso	5	0.24	2.5e-06	4.8	6.7	2.3e-11	0.70	0.02	0.93	FALSE
11	GTEx	Cells Transformed fibroblasts	TBC1D17	0.11	0.03	enet	23	0.04	6.5e-04	-4.5	7.0	2.5e-12	0.12	0.87	0.01	FALSE
12	GTEx	Cells Transformed fibroblasts	RASIP1	0.19	0.14	lasso	6	0.20	6.1e-15	-4.5	-5.7	1.6e-08	0.02	0.03	0.97	FALSE
13	GTEx	Cells Transformed fibroblasts	PRR12	0.14	0.06	enet	14	0.10	4.5e-08	6.9	6.2	5.0e-10	0.78	0.01	0.99	FALSE
14	GTEx	Colon Sigmoid	PRR12	0.20	0.01	lasso	8	0.00	4.9e-01	7.0	8.2	3.0e-16	0.72	0.02	0.56	TRUE
15	GTEx	Colon Transverse	PRR12	0.27	0.09	enet	8	0.16	4.7e-08	5.6	7.6	4.2e-14	0.74	0.14	0.86	FALSE
16	GTEx	Esophagus Mucosa	RASIP1	0.13	0.13	lasso	4	0.13	9.0e-09	5.7	-5.9	3.6e-09	0.00	0.05	0.95	FALSE
17	GTEx	Esophagus Mucosa	PRR12	0.23	0.11	lasso	6	0.21	3.2e-14	5.6	7.5	7.7e-14	0.82	0.02	0.98	FALSE
18	GTEx	Esophagus Mucosa	AP2A1	0.18	0.09	enet	8	0.13	7.7e-09	-4.5	-5.2	1.8e-07	0.08	0.99	0.00	FALSE
19	GTEx	Esophagus Muscularis	PRR12	0.19	0.16	lasso	3	0.16	6.4e-10	7.0	6.8	7.4e-12	0.99	0.00	1.00	FALSE
20	GTEx	Esophagus Muscularis	CTB-33G10.11	0.09	0.00	lasso	4	0.00	2.7e-01	6.0	6.9	6.8e-12	0.87	0.01	0.90	FALSE
21	GTEx	Heart Left Ventricle	MAMSTR	0.26	0.18	lasso	6	0.21	3.4e-11	4.6	-5.7	1.1e-08	0.01	0.02	0.98	FALSE
22	GTEx	Liver	PRRG2	0.23	0.10	lasso	2	0.12	3.1e-04	7.0	6.9	3.8e-12	0.99	0.00	0.98	FALSE
23	GTEx	Liver	PRR12	0.44	0.19	lasso	7	0.16	2.8e-05	5.6	6.3	4.0e-10	0.52	0.18	0.75	FALSE
24	GTEx	Lung	PRR12	0.13	0.11	lasso	2	0.10	5.8e-08	7.0	7.2	5.0e-13	0.99	0.00	1.00	FALSE
25	GTEx	Nerve Tibial	PRR12	0.20	0.18	lasso	3	0.17	7.4e-12	7.0	6.9	4.3e-12	0.99	0.00	1.00	FALSE
26	GTEx	Pancreas	PRR12	0.19	0.17	lasso	2	0.16	3.8e-07	7.0	7.3	2.0e-13	0.95	0.00	0.99	FALSE
27	GTEx	Skin Not Sun Exposed Suprapubic	RASIP1	0.15	0.04	lasso	6	0.08	2.9e-05	-6.4	-5.9	4.2e-09	0.01	0.01	0.98	FALSE
28	GTEx	Skin Not Sun Exposed Suprapubic	PRR12	0.24	0.25	lasso	4	0.25	5.3e-14	5.6	6.1	1.1e-09	0.47	0.97	0.03	FALSE
29	GTEx	Skin Not Sun Exposed Suprapubic	NTN5	0.19	0.07	lasso	5	0.08	2.5e-05	-4.5	-5.5	3.4e-08	-0.01	0.08	0.91	FALSE
30	GTEx	Skin Sun Exposed Lower leg	RASIP1	0.21	0.13	enet	19	0.17	1.1e-13	5.8	-6.6	4.3e-11	-0.02	0.02	0.98	TRUE
31	GTEx	Skin Sun Exposed Lower leg	PRRG2	0.23	0.18	lasso	3	0.21	1.3e-17	6.9	6.1	1.4e-09	0.97	0.01	0.99	FALSE
32	GTEx	Skin Sun Exposed Lower leg	PRR12	0.34	0.24	lasso	5	0.23	4.3e-19	5.6	5.5	3.0e-08	0.39	0.97	0.03	FALSE
33	GTEx	Skin Sun Exposed Lower leg	NTN5	0.11	0.09	enet	18	0.05	6.2e-05	-4.5	-5.3	1.4e-07	0.02	0.06	0.94	FALSE
34	GTEx	Skin Sun Exposed Lower leg	NOSIP	0.13	0.12	lasso	1	0.11	3.2e-09	6.0	6.0	2.3e-09	0.68	0.58	0.42	FALSE
35	GTEx	Skin Sun Exposed Lower leg	AP2A1	0.15	0.08	enet	10	0.07	1.9e-06	-4.7	-5.3	1.2e-07	0.03	0.99	0.00	FALSE
36	GTEx	Stomach	VRK3	0.10	-0.01	enet	10	-0.01	7.3e-01	2.5	5.2	2.0e-07	-0.03	0.07	0.08	FALSE
37	GTEx	Testis	RASIP1	0.29	0.20	lasso	8	0.30	7.5e-14	5.7	-6.4	2.0e-10	0.00	0.02	0.98	FALSE
38	GTEx	Testis	NTN5	0.16	0.02	enet	23	0.06	9.6e-04	-4.6	-5.1	2.6e-07	0.00	0.04	0.68	FALSE
39	GTEx	Thyroid	PRR12	0.47	0.34	lasso	5	0.40	3.5e-32	4.8	6.2	7.6e-10	0.53	0.99	0.01	FALSE
40	GTEx	Vagina	PRR12	0.49	0.14	lasso	6	0.32	4.6e-08	4.8	6.5	8.6e-11	0.30	0.09	0.26	TRUE
41	GTEx	Whole Blood	PNKP	0.14	0.10	enet	12	0.12	1.5e-11	-4.9	-5.9	2.8e-09	-0.09	0.99	0.00	FALSE
42	METSIM	Adipose	PRR12	0.06	0.06	enet	10	0.06	9.4e-09	7.0	7.1	1.5e-12	0.98	0.00	1.00	FALSE
43	YFS	Blood	PNKP	0.22	0.28	enet	47	0.30	3.9e-101	-4.9	-5.3	1.2e-07	0.06	1.00	0.00	FALSE
44	YFS	Blood	RPL13A	0.45	0.19	enet	53	0.34	1.8e-115	3.5	5.1	2.9e-07	0.43	1.00	0.00	FALSE
45	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FUT2	0.05	0.01	blup	52	0.01	6.1e-02	-6.6	5.9	4.6e-09	0.01	0.00	0.87	FALSE
46	The Cancer Genome Atlas	Breast Invasive Carcinoma	NTN5	0.02	0.01	enet	11	0.01	7.6e-04	-5.0	-6.1	1.3e-09	-0.03	0.01	0.81	FALSE
47	The Cancer Genome Atlas	Breast Invasive Carcinoma	PRR12	0.04	0.03	lasso	4	0.02	1.1e-05	4.9	5.5	3.5e-08	0.82	0.02	0.96	FALSE
48	The Cancer Genome Atlas	Breast Invasive Carcinoma	RASIP1	0.02	0.02	blup	56	0.03	3.8e-07	-4.7	-5.5	4.6e-08	-0.02	0.02	0.98	FALSE
49	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FUT2	0.10	0.02	blup	55	0.06	6.8e-04	-5.0	5.2	1.7e-07	0.02	0.19	0.71	FALSE
50	The Cancer Genome Atlas	Colon Adenocarcinoma	PRR12	0.04	0.02	blup	30	0.03	7.1e-03	5.8	6.3	3.6e-10	0.88	0.02	0.52	FALSE
51	The Cancer Genome Atlas	Colon Adenocarcinoma	PRRG2	0.05	0.05	lasso	2	0.02	1.9e-02	7.0	-7.0	3.0e-12	-0.99	0.00	0.91	FALSE
52	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FUT2	0.11	0.22	blup	52	0.22	6.3e-24	-4.4	5.2	1.9e-07	0.01	0.99	0.01	FALSE
53	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RASIP1	0.04	0.01	enet	10	0.02	2.3e-03	4.1	-5.3	1.2e-07	0.01	0.10	0.73	FALSE
54	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FUT2	0.10	0.01	blup	51	0.05	9.8e-04	-4.3	5.2	2.4e-07	-0.01	0.03	0.81	FALSE
55	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PRR12	0.09	0.03	lasso	6	0.06	4.0e-04	5.6	7.2	7.1e-13	0.75	0.01	0.86	FALSE
56	The Cancer Genome Atlas	Brain Lower Grade Glioma	MAMSTR	0.04	0.04	blup	47	0.06	3.9e-07	5.2	-5.2	1.7e-07	-0.02	0.15	0.85	FALSE
57	The Cancer Genome Atlas	Brain Lower Grade Glioma	SEC1	0.16	0.11	lasso	4	0.11	2.1e-12	4.2	-5.1	3.1e-07	0.03	0.66	0.31	FALSE
58	The Cancer Genome Atlas	Lung Adenocarcinoma	FUT2	0.09	0.12	blup	52	0.12	4.2e-14	-5.0	5.2	2.4e-07	0.00	0.76	0.24	FALSE
59	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PRR12	0.03	0.00	blup	30	0.01	2.1e-02	5.6	6.6	4.8e-11	0.82	0.01	0.66	FALSE
60	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FUT2	0.06	0.00	blup	53	0.05	3.5e-04	-6.6	5.2	1.8e-07	0.01	0.01	0.92	FALSE
61	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	IZUMO1	0.16	0.17	lasso	7	0.15	1.4e-06	5.7	-5.8	6.0e-09	-0.01	0.16	0.83	FALSE
62	The Cancer Genome Atlas	Prostate Adenocarcinoma	FUT2	0.05	0.06	blup	52	0.06	8.6e-07	-4.4	5.8	7.3e-09	0.00	0.04	0.96	FALSE
63	The Cancer Genome Atlas	Prostate Adenocarcinoma	PRR12	0.03	0.00	blup	30	0.01	1.1e-02	7.0	5.4	6.0e-08	0.88	0.01	0.77	FALSE
64	The Cancer Genome Atlas	Rectum Adenocarcinoma	FUT2	0.26	0.28	lasso	10	0.22	5.2e-06	-4.7	5.2	2.4e-07	0.01	0.09	0.85	FALSE
65	The Cancer Genome Atlas	Soft Tissue Sarcoma	CCDC114	0.09	0.06	lasso	4	0.05	4.6e-04	-5.6	5.3	9.0e-08	-0.03	0.00	0.96	TRUE
66	The Cancer Genome Atlas	Soft Tissue Sarcoma	RASIP1	0.05	0.06	blup	54	0.04	1.4e-03	3.9	-5.2	2.0e-07	-0.02	0.04	0.46	FALSE
67	The Cancer Genome Atlas	Thyroid Carcinoma	FUT2	0.06	0.04	blup	54	0.06	1.1e-06	3.9	5.5	4.8e-08	0.03	0.02	0.97	FALSE