TWAS hub - VRK3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Muscle Skeletal	0.0466	0.0199	6.3e-03	0.037	NA	0.031	NA	0.034	1.3e-04	NA	4.4e-04	NA	2.4e-04
2	GTEx	Prostate	0.2350	0.0960	9.2e-03	-0.009	NA	-0.011	NA	-0.008	6.3e-01	NA	8.3e-01	NA	5.5e-01
3	GTEx	Spleen	0.2900	0.0900	2.1e-04	0.061	NA	0.071	NA	0.092	1.2e-02	NA	6.8e-03	NA	2.3e-03
4	GTEx	Stomach	0.0990	0.0430	5.6e-03	-0.005	NA	-0.005	NA	-0.005	6.9e-01	NA	7.3e-01	NA	7.5e-01
5	GTEx	Testis	0.4740	0.0630	2.2e-16	0.445	NA	0.434	NA	0.413	1.3e-21	NA	5.2e-21	NA	9.7e-20
6	GTEx	Thyroid	0.0890	0.0370	3.5e-03	0.007	NA	0.005	NA	0.001	8.8e-02	NA	1.2e-01	NA	2.4e-01
7	NTR	Blood	0.0456	0.0118	1.4e-09	0.028	0.039	0.038	0.040	0.035	1.6e-09	1.4e-12	1.9e-12	6.9e-13	1.3e-11
8	YFS	Blood	0.2311	0.0292	0.0e+00	0.353	0.355	0.361	0.381	0.358	2.2e-121	1.9e-122	6.5e-125	1.1e-133	1.5e-123

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.7	4.3	8.4	-2.4	-1.4	-1.5	-1.1	-2.0	-2.3	-2.9	-2.4
Medication: Amlodipine	3.4	4.8	11.0	-2.8	-2.7	-3.3	-1.6	-2.2	-0.6	-1.3	-1.8
Medication: Lansoprazole	3.1	3.6	9.3	-1.8	-0.9	-0.8	-3.1	-1.3	-1.9	-2.1	-2.3
High blood pressure (mother)	2.9	4.0	8.4	1.5	2.9	1.8	2.5	1.9	1.9	1.6	1.4
Trunk fat-free mass	2.6	14.7	42.4	3.2	2.9	2.6	6.5	3.6	3.6	3.8	3.3
Trunk predicted mass	2.6	14.7	42.1	3.2	2.9	2.6	6.5	3.6	3.5	3.7	3.3
Ever had bowel cancer screening	2.6	3.0	5.6	-1.5	-2.2	-2.4	-1.5	-0.9	-1.2	-2.2	-1.4
Basal metabolic rate	2.5	13.6	31.0	3.3	2.9	3.1	5.6	3.4	3.6	3.6	3.4
Arm predicted mass (left)	2.5	12.6	35.3	3.0	2.7	2.6	5.9	3.3	3.3	3.3	3.1
Headache pain in last month	2.4	4.1	10.5	2.5	2.0	2.0	3.2	1.4	1.1	1.5	1.6
Shortness of breath walking on level ground	2.4	2.8	12.0	1.3	1.4	1.3	3.5	0.8	0.2	1.8	1.2
Whole body fat-free mass	2.4	13.4	35.9	3.1	2.7	2.6	6.0	3.3	3.5	3.6	3.3
Whole body water mass	2.4	13.7	37.4	3.1	2.7	2.6	6.1	3.3	3.5	3.6	3.3
Arm fat-free mass (left)	2.4	12.0	32.1	3.0	2.6	2.5	5.7	3.4	3.2	3.2	3.1
Rheumatoid Arthritis	2.3	3.2	5.2	1.4	1.8	1.9	-0.8	1.9	2.3	2.1	1.8
Supplements: Vitamin C	2.3	2.7	5.8	-1.5	-1.9	-2.4	-1.3	-1.1	-1.1	-1.6	-1.8
Major Depression (MDD)	2.2	2.6	4.4	1.7	1.8	2.1	0.0	1.7	1.5	1.5	1.8
Prostate Cancer	2.2	3.1	5.6	1.8	1.6	1.0	1.1	1.6	2.3	1.9	2.4
Impedance of whole body	2.2	11.4	42.9	-2.5	-2.6	-1.4	-6.5	-3.0	-2.8	-2.7	-2.9
Impedance of arm (left)	2.1	9.8	39.0	-2.2	-2.2	-1.0	-6.2	-3.1	-2.4	-2.5	-2.7
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.5	5.9	-2.4	-0.3	-1.2	1.2	-2.4	-1.3	-1.0	-1.6
Leg fat-free mass (left)	2.0	10.7	22.8	3.0	2.4	2.7	4.8	2.8	3.4	3.3	3.2
Leg predicted mass (left)	2.0	10.8	21.8	3.1	2.5	2.7	4.7	2.9	3.5	3.4	3.2
Weight	2.0	9.6	13.5	3.0	2.8	3.3	3.7	2.8	3.2	2.9	2.9
Impedance of arm (right)	2.0	9.2	34.0	-2.3	-2.2	-0.9	-5.8	-3.3	-2.3	-2.3	-2.7
Hip circumference	2.0	8.7	13.1	3.2	2.9	3.6	2.5	2.7	2.8	2.8	2.9
Time employed in main current job	2.0	2.3	6.4	-1.5	-0.1	-0.3	-2.5	-2.2	-1.2	-1.3	-1.3
Arm predicted mass (right)	2.0	10.5	29.7	2.8	2.2	2.1	5.4	3.3	2.9	2.9	3.0
HbA1C	1.9	2.1	5.3	-1.0	-1.2	0.1	-1.1	-1.1	-2.3	-1.6	-1.9
Ever used hormone-replacement therapy (HRT)	1.9	2.4	5.6	-2.0	-0.4	-0.8	-2.4	-1.9	-1.1	-1.1	-1.7
Medication: Atenolol	1.9	2.4	7.2	0.5	2.0	1.9	2.7	0.3	1.5	1.1	0.8
Arm fat-free mass (right)	1.9	9.9	29.1	2.6	2.1	2.1	5.4	3.1	2.9	2.9	2.9
Leg fat-free mass (right)	1.9	10.4	25.2	2.8	2.4	2.7	5.0	2.6	3.3	3.3	3.0
Leg predicted mass (right)	1.9	10.3	25.1	2.8	2.4	2.6	5.0	2.6	3.3	3.3	3.0
Deep venous thrombosis (DVT) (self-reported)	1.9	2.5	5.8	0.6	1.2	0.6	1.8	-0.2	2.4	2.4	1.7
Hand grip strength (right)	1.8	4.8	7.6	2.5	1.1	1.1	2.7	2.8	1.6	2.1	2.7
Medication: Aspirin	1.8	2.3	4.3	-2.1	-1.5	-1.3	-0.7	-1.6	-1.2	-1.7	-1.7
Number of self-reported non-cancer illnesses	1.8	3.1	5.2	-1.6	-2.0	-1.6	0.5	-1.1	-2.3	-2.1	-2.1
Pain all over the body in last month	1.7	1.9	3.3	-1.6	-1.1	-1.2	-0.4	-1.8	-1.5	-1.5	-1.3
Depression (self-reported)	1.7	2.0	4.9	-1.2	-1.1	-1.5	-0.5	-1.1	-1.7	-2.2	-1.4
Hand grip strength (left)	1.6	4.1	6.0	2.4	1.0	1.4	2.4	2.4	2.0	1.8	2.4
Chronic bronchitis/emphysema (father)	1.6	1.9	3.9	-1.1	-0.9	-1.5	-1.1	-0.8	-1.6	-2.0	-1.6
Impedance of leg (left)	1.6	7.6	26.1	-2.2	-2.3	-1.5	-5.1	-1.9	-2.7	-2.4	-2.5
Had menopause	1.6	2.0	4.5	-1.2	-0.9	-0.8	-2.1	-1.3	-1.0	-2.0	-1.4
Mouth/teeth dental problems: Dentures	1.6	2.8	4.3	-1.9	-1.5	-1.5	-0.9	-2.1	-1.7	-1.6	-1.9
Illnesses of mother	1.6	2.0	3.5	-1.2	-1.9	-1.5	-1.6	-0.9	-1.6	-1.0	-1.1
Mouth/teeth dental problems: Loose teeth	1.6	1.9	3.4	-1.9	-1.0	-1.7	-1.2	-1.5	-1.0	-1.1	-1.3
Ever depressed for a whole week	1.6	1.9	4.8	-1.5	-1.3	-0.9	1.0	-1.6	-2.2	-1.0	-1.1
Alcohol intake versus 10 years previously	1.5	2.2	3.9	-1.2	-1.6	-0.5	-2.0	-0.8	-1.8	-1.9	-1.2
Birth weight	1.5	3.2	8.0	1.8	2.1	1.9	2.8	1.6	1.3	0.8	1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.0	4.4	2.0	1.1	1.6	2.0	1.9	1.2	2.1	1.7
Medication: Gliclazide	1.5	1.7	3.8	-1.6	-1.3	-1.5	0.1	-1.9	-1.0	-0.9	-1.4
Body Mass Index (BMI) (2010)	1.4	1.9	3.1	1.0	1.6	1.6	1.8	0.8	1.7	1.2	1.0
Migraine (self-reported)	1.4	1.8	7.2	-0.5	-1.6	-1.1	2.7	-1.0	-1.0	-0.3	-0.9
Hearing aid user	1.4	1.5	3.5	1.3	1.3	1.6	1.9	0.8	0.7	0.8	0.9
Ever smoked	1.4	2.4	4.4	1.6	1.3	1.7	1.3	1.6	1.2	2.1	1.6
BMI	1.3	7.7	11.5	2.9	3.0	3.0	3.4	2.6	2.6	2.0	2.4
Multivitamins +/- minerals	1.3	1.6	4.3	1.0	1.9	0.1	0.4	0.8	2.1	1.4	1.2
Medication: Ramipril	1.3	1.6	4.8	-0.7	-1.9	-1.4	-2.2	-0.6	-0.2	-0.9	-0.9
Medication: Ibuprofen	1.3	1.5	7.2	-0.5	1.7	0.4	2.7	-0.7	0.4	1.0	0.4
Osteoporosis (self-reported)	1.3	1.7	2.6	-1.2	-0.4	-0.9	-1.4	-1.6	-1.4	-1.5	-1.3
Supplements: Calcium	1.3	1.5	3.7	1.0	1.2	0.7	0.0	0.9	1.9	1.6	1.3
Supplements: Zinc	1.2	1.3	2.3	1.1	1.3	0.5	1.1	0.5	1.5	1.4	1.4
Impedance of leg (right)	1.2	5.9	25.8	-1.6	-1.9	-1.2	-5.1	-1.3	-2.3	-1.8	-1.9
Waist circumference	1.2	4.5	8.4	2.3	2.2	2.9	1.7	2.0	2.0	1.8	1.9
Hearing difficulty/problems with background noise	1.2	1.8	5.9	-1.5	0.0	-0.2	-0.2	-0.9	-2.4	-2.0	-1.4
Blood clot in the leg (DVT)	1.2	1.6	3.6	0.1	0.9	0.2	1.8	-0.5	1.9	1.9	1.1
Number of full brothers	1.2	1.5	3.0	-0.9	-1.1	-1.7	1.6	-1.2	-1.1	-1.1	-1.0
Leg fat mass (right)	1.2	4.8	6.9	2.5	2.0	2.6	1.4	2.5	2.3	1.8	2.2
Arm fat mass (left)	1.2	4.8	7.5	2.4	2.1	2.7	2.0	2.3	2.2	1.5	2.0
Miserableness	1.2	2.1	3.6	-1.8	-1.1	-1.3	0.6	-1.9	-1.1	-1.5	-1.8
Relative age of first facial hair	1.1	2.3	8.1	-1.5	-1.2	-0.7	-2.9	-0.9	-1.2	-1.2	-1.7
Hair/balding pattern: Pattern 3	1.1	1.7	4.4	-2.1	-0.6	-1.0	-0.2	-1.7	-0.8	-1.0	-1.8
Happiness	1.1	1.4	6.5	0.3	1.7	0.9	2.5	-0.2	0.1	0.6	0.5
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	6.7	-0.7	1.6	-0.0	2.6	-0.8	0.5	0.9	0.2
Arm fat mass (right)	1.1	4.5	7.3	2.3	2.1	2.7	2.1	2.0	2.1	1.5	2.0
Medication: Aspirin	1.1	1.5	3.3	-1.8	-1.1	-1.0	-0.5	-1.3	-0.8	-1.2	-1.4
Leg fat mass (left)	1.1	4.2	6.1	2.3	1.9	2.5	1.4	2.3	2.2	1.6	2.1
LDL Cholesterol	1.0	1.6	4.9	1.0	1.7	2.2	1.0	0.5	1.1	1.1	0.6
Average weekly spirits intake	1.0	1.2	1.9	-1.4	-0.9	-1.1	0.1	-0.8	-1.3	-1.4	-1.3
Frequency of depressed mood in last 2 weeks	1.0	1.5	2.7	1.6	1.2	0.4	1.6	0.8	0.9	1.3	1.3
Hearing difficulty/problems: Yes	1.0	1.5	2.3	-1.5	-0.4	-1.2	1.1	-1.3	-1.5	-1.4	-0.9
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	3.1	-1.2	1.1	-0.1	1.3	-1.8	1.3	0.3	0.1
Qualifications: CSEs or equivalent	1.0	1.3	2.3	-0.8	-1.2	-0.7	-1.4	-1.0	-1.5	-1.1	-1.0
Sitting height	1.0	7.3	27.0	1.9	1.7	1.8	5.2	1.8	2.1	3.1	2.1
Body mass index (BMI)	1.0	4.3	5.4	2.2	2.1	2.3	2.3	2.1	2.1	1.3	2.0
Ever unenthusiastic/disinterested for a whole week	1.0	1.3	4.5	-0.8	-0.6	0.0	1.3	-1.3	-2.1	-0.8	-0.8
Fluid intelligence score	1.0	2.1	3.9	1.5	1.1	1.6	0.1	1.2	1.6	2.0	1.7
Number of live births	1.0	1.4	3.3	-0.9	-1.6	-1.8	-1.1	-0.8	-1.1	-1.1	-0.7
Comparative body size at age 10	1.0	2.7	8.7	1.1	1.9	1.8	0.7	0.7	2.9	1.7	1.2
Whole body fat mass	1.0	4.1	6.8	2.2	1.9	2.6	1.4	2.1	2.2	1.5	2.0
Age at last live birth	1.0	1.4	3.3	1.2	0.7	1.0	0.3	1.8	1.2	1.4	1.1
Medication: Lisinopril	1.0	1.3	3.6	0.7	1.9	1.3	0.0	0.5	1.7	0.8	0.7
Unable to work because of sickness or disability	1.0	1.3	2.8	-1.4	-0.8	-0.8	-0.8	-1.7	-1.1	-0.9	-1.3
Alzheimer’s Disease (in mother)	0.9	1.0	1.9	-0.8	-1.4	-1.1	-1.3	-1.3	-0.4	-0.9	-0.6
Verbal and Numeric Reasoning (VNR)	0.9	2.3	3.5	1.8	1.1	1.3	0.3	1.7	1.5	1.8	1.9
Past tobacco smoking	0.9	1.6	2.8	-1.4	-1.0	-1.6	-1.5	-1.0	-0.4	-1.7	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	3.6	-1.0	-1.0	-1.4	0.0	-1.1	-1.9	-1.2	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	1.9	-1.3	0.1	-1.4	0.7	-1.4	-1.0	-1.1	-1.1
Medication for pain relief, constipation, heartburn	0.9	1.5	2.7	1.6	-0.7	1.1	-1.6	1.3	0.7	1.2	1.1
Mean time to correctly identify matches	0.9	1.7	4.1	-1.1	-0.7	-2.0	-1.6	-0.7	-1.2	-1.3	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	3.7	-1.3	-1.0	-1.9	0.1	-1.7	-1.4	-1.4	-1.5
Tinnitus: Yes, now most or all of the time	0.9	1.0	3.4	-0.6	-1.8	-1.3	0.9	-1.2	-0.7	-0.4	-0.3
High cholesterol (Self-reported)	0.9	1.6	5.0	-0.7	-2.2	-0.8	-0.8	-0.7	-1.6	-0.9	-1.4
Medication: Atorvastatin	0.9	1.1	4.6	0.1	-1.4	-1.2	-2.1	-0.0	-0.1	-0.6	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	2.4	-1.1	0.0	-0.7	-0.9	-1.5	-0.8	-1.3	-1.2
Reaction Time	0.8	1.5	5.2	-1.1	-0.8	-2.3	-0.9	-0.7	-1.2	-1.1	-1.0
Relative age voice broke	0.8	1.3	6.2	0.4	1.0	1.6	-2.5	-0.1	0.4	0.6	-0.0
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	1.8	1.0	1.3	0.6	1.3	0.8	0.2	0.5	0.6
Length of working week for main job	0.8	0.9	2.2	1.0	0.2	0.8	-0.2	0.0	1.0	1.4	1.5
Peak expiratory flow (PEF)	0.8	1.8	3.3	1.6	0.9	0.9	1.8	0.9	1.3	1.5	1.4
Heart disease (mother)	0.8	0.9	2.3	0.8	1.1	1.4	1.5	1.1	0.3	0.0	0.5
Suffer from ‘nerves’	0.8	1.2	2.6	-1.1	-0.9	-1.4	-1.4	-1.6	-0.6	0.2	-0.7
Chest pain or discomfort	0.8	1.1	2.0	-1.4	-1.1	-0.5	-0.1	-1.4	-0.6	-1.2	-1.3
Wears glasses or contact lenses	0.8	0.9	2.4	0.2	1.0	1.5	-1.6	-0.2	-0.6	-1.0	-0.6
Heart disease (siblings)	0.8	0.9	2.0	-1.4	0.5	-0.5	-1.0	-1.4	0.2	-0.9	-1.1
Pack years of smoking	0.8	1.2	2.2	-1.3	-0.7	-0.5	1.2	-0.9	-1.2	-1.1	-1.5
Bipolar Disorder (2018)	0.7	1.1	2.7	1.6	1.0	1.2	1.0	0.7	0.2	0.4	1.5
Bipolar Disorder or Schizophrenia	0.7	1.7	3.2	1.8	1.4	1.2	1.1	1.1	0.8	0.9	1.7
Alzheimer’s Disease (including proxy)	0.7	1.0	2.3	-0.9	-0.8	-1.5	-1.4	-1.3	-0.3	-0.4	0.0
Lupus	0.7	1.0	1.8	-1.0	-1.3	-1.2	0.8	-1.1	-1.2	-0.8	-0.7
Number of treatments/medications taken	0.7	1.2	3.0	-0.8	-0.7	-1.1	-0.3	-0.6	-1.7	-1.4	-1.2
Medication: Simvastatin	0.7	1.0	1.9	-1.0	-1.3	-0.3	-0.5	-0.5	-1.3	-1.1	-1.4
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	7.2	-0.2	0.9	0.1	2.7	-0.7	0.2	0.4	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.3	0.1	1.5	1.3	-1.3	-0.0	0.7	-0.1	0.2
Loud music exposure frequency	0.7	0.7	2.0	1.1	1.0	1.4	0.3	1.0	-0.3	-0.4	0.4
Health satisfaction	0.7	1.0	3.8	-1.3	0.7	-0.6	0.7	-1.9	-0.1	-0.4	-0.9
Eye problems/disorders: None of the above	0.7	0.8	1.7	0.9	0.1	0.3	-1.1	1.3	1.0	0.9	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	2.2	-0.4	-1.2	-1.5	-1.0	-1.2	-0.1	-0.4	0.3
Fractured/broken bones in last 5 years	0.7	1.0	3.6	0.8	-0.9	0.1	-1.9	0.8	-0.8	-1.0	-0.5
Basal cell carcinoma (self-reported)	0.7	0.8	3.5	-0.1	-0.1	0.9	-1.9	-0.4	-0.1	-1.3	-0.6
Depression (Nagel 2018)	0.6	0.9	1.8	1.3	0.3	0.5	1.4	0.9	0.7	1.1	0.9
Breast Cancer	0.6	1.4	6.8	-1.5	-1.1	-2.6	0.2	-0.3	0.5	-0.3	-0.3
Medication: Metformin	0.6	0.8	3.2	-0.4	0.4	0.2	-1.8	-1.1	0.1	-0.9	-0.8
Age when periods started (menarche)	0.6	1.4	3.6	-1.2	-1.9	-1.7	0.7	-0.8	-0.7	-0.8	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	3.8	-0.9	-1.9	-1.0	0.8	-0.5	-1.9	-0.6	-0.6
Trunk fat mass	0.6	2.4	4.8	1.7	1.5	2.2	1.1	1.5	1.8	1.0	1.4
Hair/balding pattern: Pattern 2	0.6	0.7	1.4	-0.5	-1.2	-1.1	-0.4	0.3	-1.1	-1.1	-0.3
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.8	0.4	0.1	0.3	-0.5	0.3	-1.7	-1.4	-1.0
Noisy workplace	0.6	0.7	1.9	-0.8	-0.4	-0.4	1.4	-1.2	-0.6	-0.8	-0.5
Standing height	0.6	6.1	12.0	2.0	1.4	2.0	3.5	1.8	2.5	3.5	2.2
Worry too long after embarrassment	0.6	1.1	4.5	0.0	2.1	1.4	0.3	-0.8	0.6	1.0	0.5
Age at first live birth	0.6	1.0	3.6	0.8	0.1	0.9	0.5	1.9	1.1	1.1	0.6
Alcohol intake frequency.	0.6	1.5	10.4	0.2	-0.0	0.4	3.2	-0.7	0.2	0.6	0.3
Family relationship satisfaction	0.6	0.8	2.5	1.3	-0.1	0.5	0.1	1.6	-0.6	0.4	1.0
Illnesses of father: None of the above (group 1)	0.6	0.8	2.2	0.7	0.6	0.8	0.3	0.6	1.5	1.1	0.9
Medication: Paracetamol	0.6	0.9	3.3	-0.6	1.1	-0.6	1.8	-0.1	-1.0	-0.7	-0.3
Alcohol drinker status: Never	0.6	0.8	2.5	-0.7	-0.7	-1.4	1.6	-0.7	-0.0	0.5	-0.0
Commuting to job workplace: Cycle	0.6	0.7	2.9	-0.8	-0.3	0.0	-1.7	-1.0	-0.6	-0.4	-0.9
Myopia	0.6	0.8	3.0	0.8	-0.1	-0.3	-1.7	1.2	0.9	0.3	0.8
Pain experienced in last month	0.6	0.9	5.1	-0.7	-0.9	-0.6	-2.2	-0.2	-0.1	-0.7	-0.6
Blood Platelet Count	0.5	5.4	13.0	2.0	2.7	3.6	1.5	1.1	2.1	3.0	1.5
Blood White Count	0.5	3.5	6.9	2.6	1.8	2.1	0.4	1.0	2.2	1.9	2.0
Lung FVC	0.5	2.3	5.6	-1.6	-0.8	-0.8	-0.6	-2.4	-1.7	-1.8	-1.5
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.5	-1.1	0.1	0.1	0.4	-1.2	-1.0	-0.7	-0.9
Current tobacco smoking	0.5	0.8	2.0	-0.8	-1.4	-0.9	1.3	-0.3	-0.9	-0.3	-0.6
Stomach or abdominal pain in last month	0.5	0.6	2.0	-0.0	1.4	0.4	1.2	-0.4	0.8	0.6	0.4
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.8	0.4	1.3	-0.0	0.5	0.1	1.0	1.0	1.0
Nervous feelings	0.5	1.0	2.1	-1.2	-1.0	-0.5	-0.7	-1.5	-1.3	-0.4	-1.0
Illnesses of siblings	0.5	0.7	2.8	1.0	-1.7	0.2	0.4	1.0	-0.8	-0.1	0.3
Arm fat percentage (right)	0.5	1.8	4.9	1.6	1.5	2.2	0.2	1.2	1.4	0.6	1.1
Prospective memory result	0.5	0.6	3.6	-0.4	0.4	-0.0	1.9	0.3	0.6	0.5	0.4
Pulse wave Arterial Stiffness index	0.5	0.6	2.9	0.4	1.0	-0.2	1.7	0.4	0.6	0.5	0.5
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.7	-0.4	-0.8	-0.9	1.6	-1.0	0.6	0.7	0.6
High blood pressure (siblings)	0.5	0.8	2.9	-0.1	1.7	0.5	-0.6	-0.0	1.5	0.4	0.5
Leg fat percentage (right)	0.5	1.8	3.7	1.6	1.6	1.9	-0.7	1.6	1.2	0.3	1.0
Comparative height size at age 10	0.5	2.5	5.7	1.7	0.7	1.1	2.4	1.2	1.4	2.0	1.6
Leg pain on walking	0.5	0.7	2.2	-0.7	0.9	0.1	1.5	-0.6	-0.8	-0.7	-0.7
Smoking status: Previous	0.5	0.7	2.0	1.0	0.9	1.4	0.7	0.4	-0.2	0.9	0.7
Average weekly red wine intake	0.5	0.7	1.6	-0.3	1.0	0.4	-0.9	0.1	1.1	1.3	0.7
Friendships satisfaction	0.5	0.6	1.7	0.4	0.9	0.1	0.7	0.4	0.5	1.3	0.9
Commuting to job workplace: Walk	0.5	0.5	1.6	0.7	0.9	1.3	-0.6	-0.1	0.6	0.4	0.5
Breast cancer (self-reported)	0.5	0.6	3.0	-0.1	0.6	-0.7	1.7	-0.7	0.5	-0.4	0.1
Smoking status: Current	0.5	0.7	2.0	-0.6	-1.4	-0.9	1.3	-0.3	-0.7	-0.0	-0.5
Medication: Blood pressure	0.5	1.0	4.0	-1.3	-0.2	-0.8	-0.2	-2.0	-0.3	-0.4	-1.1
Supplements: Fish oil (including cod liver oil)	0.5	0.6	2.5	0.1	-1.6	-0.9	-0.3	-0.1	-0.9	-0.9	-0.2
Medication: Bendroflumethiazide	0.5	0.8	2.0	-0.9	-0.8	-0.4	-0.4	-1.1	-0.8	-1.4	-1.0
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.5	-0.9	0.9	-1.2	0.1	-1.0	0.6	-0.4	-0.6
Diastolic blood pressure, automated reading	0.5	1.5	2.3	1.2	1.3	0.6	1.3	1.4	1.2	1.5	1.2
Schizophrenia vs Biploar Disorder	0.4	0.5	2.6	-0.7	-1.6	-0.9	0.1	-0.2	-0.4	-0.3	-0.3
Alzheimer’s Disease (in father)	0.4	0.4	1.4	0.4	0.6	-0.4	-0.0	0.4	0.1	1.1	1.2
Age at First Birth	0.4	0.6	2.4	0.8	0.6	0.5	-1.6	0.6	-0.7	0.1	0.3
Primary Biliary Cirrhosis	0.4	0.6	1.9	1.4	-0.8	0.1	1.0	0.4	-0.8	-0.2	0.2
Schizophrenia (2014)	0.4	0.9	1.3	1.2	1.1	0.8	0.9	0.8	0.8	1.1	0.7
Height	0.4	7.8	28.8	1.8	1.3	1.7	5.4	1.9	2.6	3.4	2.0
Waist Hip Ratio (WHR)	0.4	1.7	2.7	-1.3	-1.3	-1.1	-1.4	-1.3	-1.6	-1.1	-1.4
Sensitivity / hurt feelings	0.4	0.8	3.3	0.3	1.5	1.8	-0.5	-0.2	0.1	0.4	0.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.3	-1.2	0.3	-0.9	0.1	-1.1	0.1	-0.3	-0.6
Medication for hormone replacement therapy	0.4	0.4	1.2	-0.5	-1.1	-0.4	-0.6	-0.7	-0.6	-0.5	-0.7
Vitamin and mineral supplements	0.4	0.5	1.3	0.1	-0.3	1.0	1.1	-0.1	-1.1	-0.4	0.1
Severe depression (siblings)	0.4	0.4	1.5	-1.0	-0.1	-0.3	0.4	-1.2	0.0	0.4	-0.5
Pack years adult smoking proportion	0.4	0.7	1.7	-0.9	-0.5	-0.1	1.3	-0.6	-0.7	-0.7	-1.0
Taking other prescription medications	0.4	0.6	1.2	-0.9	-0.2	-0.6	0.3	-0.8	-1.0	-1.1	-0.9
Hayfever, allergic rhinitis or eczema	0.4	0.9	2.3	-0.6	-0.2	-0.7	-1.1	-0.7	-0.5	-1.4	-1.5
Had other major operations	0.4	0.5	2.7	-0.1	0.9	0.1	1.7	-0.0	-0.1	0.2	0.1
Mouth/teeth dental problems	0.4	0.6	1.1	1.0	0.2	0.7	0.7	0.9	0.3	0.9	1.0
Heart attack	0.4	0.5	1.1	-0.2	-0.8	0.1	-0.8	0.3	-1.1	-0.8	-0.8
Neuroticism score	0.4	0.8	2.5	-1.2	0.7	0.1	0.1	-1.6	-0.7	-0.4	-1.0
Father’s age at death	0.4	0.6	2.2	-0.2	-0.7	-1.2	-1.5	0.4	-0.4	-0.3	-0.1
Medication: Cholesterol lowering	0.4	0.6	1.0	-0.8	-0.9	-0.4	-0.9	-0.1	-0.6	-0.8	-1.0
Birth weight of first child	0.4	0.7	4.8	0.2	-0.1	-0.1	2.2	0.3	0.5	0.4	0.3
Pulse wave reflection index	0.4	0.5	2.4	0.6	-0.2	-0.8	1.5	0.2	-0.5	-0.7	-0.1
Chronic bronchitis/emphysema (mother)	0.4	0.5	0.9	-0.9	-0.4	-0.9	-0.8	-0.7	0.1	-0.5	-0.8
Number of children fathered	0.4	0.4	1.0	-0.5	-0.5	-0.2	-0.8	-1.0	-0.9	-0.7	-0.4
Pulse wave peak to peak time	0.4	0.5	2.4	-0.3	-0.9	0.3	-1.5	-0.3	-0.4	-0.3	-0.4
Angina (self-reported)	0.4	0.5	3.2	-0.2	0.4	0.9	1.8	0.1	-0.1	0.1	-0.4
Number of full sisters	0.4	0.4	1.0	-0.6	1.0	1.0	-0.6	-0.7	0.3	-0.3	-0.4
Overall health rating	0.4	1.0	3.0	-1.3	0.0	-0.1	-0.3	-1.7	-0.1	-0.8	-1.5
Commuting to job workplace: Car/motor vehicle	0.4	0.5	2.2	-0.7	-0.4	-1.5	0.5	-0.8	0.5	-0.3	-0.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	2.0	-0.0	-1.4	-0.8	-0.6	-0.6	-0.6	-0.2	-0.3
Illnesses of siblings: Diabetes	0.4	0.5	1.0	-0.9	0.4	-0.1	-0.7	-0.7	-0.8	-0.8	-1.0
Arm fat percentage (left)	0.4	1.6	4.2	1.5	1.4	2.0	-0.1	1.2	1.3	0.2	1.0
Long-standing illness, disability or infirmity	0.4	0.7	1.1	-1.0	0.5	-0.2	0.8	-1.0	-0.8	-0.9	-1.0
Eye problems/disorders: Cataract	0.4	0.4	2.6	0.2	0.3	-0.6	1.6	-0.0	-0.5	-0.0	0.1
Back pain experienced in last month	0.4	0.6	3.5	-0.1	0.9	-0.5	1.9	0.4	-0.0	0.0	-0.0
Osteoarthritis (self-reported)	0.4	0.5	1.8	-0.4	0.9	0.7	1.3	-0.1	0.2	-0.4	-0.8
Average weekly champagne plus white wine intake	0.4	0.6	2.8	0.1	-1.0	-0.7	-1.7	-0.0	-0.3	0.5	0.0
Ever taken oral contraceptive pill	0.4	0.4	1.1	0.4	0.6	0.5	-0.1	0.5	0.9	1.0	0.7
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.7	-0.4	-0.1	-0.4	1.6	-0.6	-0.7	-0.5	-0.4
Intelligence (Savage-Jansen 2018)	0.3	1.0	1.7	1.3	1.0	1.2	0.2	0.6	0.8	1.2	1.0
Schizophrenia (2018)	0.3	0.7	1.1	0.9	1.0	0.6	0.6	0.8	0.9	0.8	1.0
Worry (Nagel 2018)	0.3	0.6	1.9	-0.5	-0.5	-0.7	-1.4	-1.0	-0.6	0.2	-0.6
Mean Putamen Volume	0.3	0.3	0.6	-0.8	-0.8	-0.4	0.1	-0.5	-0.3	-0.5	-0.7
Fasting Glucose	0.3	0.4	1.0	-1.0	0.0	-0.8	0.4	-0.5	-0.5	-0.8	-0.5
HDL Cholesterol	0.3	0.4	1.1	-0.6	-1.1	-0.8	-0.6	-0.9	-0.1	0.3	0.1
Smoking Status	0.3	0.7	1.8	-0.5	-1.4	-1.0	1.1	-0.5	-1.1	0.4	-0.2
Allergy or Eczema	0.3	0.7	1.6	-0.6	1.1	-0.3	-0.8	-0.9	0.3	-1.0	-1.2
Hypothyroidism (self reported)	0.3	0.8	1.4	-1.2	-1.0	-1.2	0.2	-0.0	-0.3	-1.1	-1.1
Angina	0.3	0.4	2.3	-0.3	0.2	0.5	1.5	-0.1	-0.1	-0.1	-0.5
Diabetes (father)	0.3	0.3	0.7	0.5	0.9	0.7	-0.7	-0.4	-0.6	-0.3	0.0
Fed-up feelings	0.3	0.6	1.4	-0.5	1.0	0.1	1.1	-1.2	-0.6	-0.3	-0.7
Serious illness, injury or assault to yourself	0.3	0.3	1.3	-0.3	0.8	0.1	1.1	-0.3	0.1	-0.5	-0.3
Supplements: Glucosamine	0.3	0.4	2.1	0.0	-1.1	-1.4	-0.4	0.3	-0.3	0.1	0.0
Number of incorrect matches in round	0.3	0.6	1.4	-0.4	-0.4	-0.8	-1.2	-1.1	0.7	0.5	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	2.1	-0.8	-1.4	-0.6	0.6	-0.1	-1.5	-0.6	-0.3
Worrier / anxious feelings	0.3	0.5	1.4	-0.8	0.1	0.4	-0.6	-1.2	-0.6	-0.3	-1.0
Qualifications: A levels/AS levels or equivalent	0.3	0.7	1.9	-0.6	-1.2	-1.4	1.2	-0.5	-0.4	-0.4	-0.2
Lung cancer (father)	0.3	0.3	0.8	-0.3	0.5	0.5	-0.2	-0.8	0.6	-0.0	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.9	-1.0	0.6	-0.2	0.2	-0.9	0.1	-0.8	-0.7
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	1.3	0.1	0.7	0.0	-1.1	0.0	0.9	-0.1	0.1
Medication: Paracetamol	0.3	0.6	2.4	-0.2	1.4	-0.1	1.5	0.2	-0.2	-0.4	-0.1
Glaucoma (self-reported)	0.3	0.4	1.4	-0.3	-0.1	0.3	1.2	-0.6	0.6	0.7	0.4
Exposure to tobacco smoke outside home	0.3	0.4	1.4	0.2	-0.1	0.3	0.1	0.4	1.2	1.0	0.6
Neck or shoulder pain in last month	0.3	0.4	0.7	-0.8	-0.7	-0.7	0.6	-0.8	-0.5	-0.4	-0.6
Medication: Allopurinol	0.3	0.4	1.6	-0.1	-0.1	0.5	0.0	1.3	-1.0	-0.3	-0.5
Medication: Seretide 50 evohaler	0.3	0.3	1.2	0.4	0.4	-0.6	-0.7	0.2	0.3	1.1	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.9	-0.5	0.5	-0.6	-0.8	-1.0	-0.3	-0.1	-0.4
Loneliness, isolation	0.3	0.4	2.1	0.1	-0.2	-0.5	1.5	-0.5	-0.3	0.2	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.3	0.2	1.1	0.2	0.8	0.7	0.6	-0.2	0.6
Medication for cholesterol	0.3	0.4	1.1	0.6	1.1	0.6	0.1	1.0	0.5	-0.0	0.6
Mineral and other dietary supplements	0.3	0.4	0.7	-0.9	0.4	0.4	0.7	-0.9	-0.3	-0.1	-0.7
Leg fat percentage (left)	0.3	1.2	2.8	1.2	1.2	1.7	-0.7	1.4	0.8	-0.1	0.7
Number of operations (self-reported)	0.3	0.4	1.0	-1.0	-0.4	-0.7	-0.2	-0.9	-0.5	-0.6	-0.7
Average weekly beer plus cider intake	0.3	0.4	1.2	0.7	1.0	1.1	0.2	0.5	-0.1	0.0	0.1
Irritability	0.3	0.5	1.0	-1.0	0.9	-0.1	0.3	-1.0	0.3	-0.4	-1.0
Risk taking	0.3	0.4	1.9	0.7	-0.0	0.3	-0.4	1.4	-0.0	0.2	0.7
Cholesterol lowering medication	0.3	0.4	2.0	0.2	-1.4	-0.2	-0.8	-0.4	-0.6	-0.4	-0.3
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.7	-0.1	-0.8	0.2	-0.7	0.4	-0.9	-0.7	-0.6
Alcohol drinker status: Previous	0.3	0.4	1.0	-0.1	-0.6	0.4	1.0	-0.5	-0.5	-0.9	-0.6
Depressed Affect (Nagel 2018)	0.2	0.4	1.3	0.1	1.2	0.9	0.7	-0.6	0.1	0.4	0.0
Neuroticism (Nagel 2018)	0.2	0.5	1.8	0.0	1.4	0.9	-0.0	-0.9	0.4	0.6	-0.1
Crohns Disease (2017)	0.2	0.4	1.0	-0.7	0.3	0.6	-0.7	-1.0	-0.2	0.3	-0.8
Irritable Bowel Disease (IBD)	0.2	0.5	1.4	-0.8	0.1	0.6	-0.4	-1.2	-0.3	0.8	-0.5
Ovarian Cancer	0.2	0.3	1.4	0.4	0.4	0.2	0.3	0.2	0.6	1.2	0.1
Triglycerides	0.2	0.4	1.4	0.3	1.2	1.0	0.4	-0.1	0.4	0.2	0.2
Ulcerative Colitis	0.2	0.2	0.6	-0.1	-0.7	-0.4	-0.5	-0.0	-0.8	0.3	-0.5
Blood Eosinophil Count	0.2	1.7	5.6	2.4	0.5	1.4	-0.4	1.6	1.2	0.9	1.1
Blood Red Count	0.2	1.7	8.6	0.0	-0.6	-1.6	-2.9	-1.1	0.2	0.5	0.2
Cardiovascular Disease	0.2	0.7	1.6	-0.4	-1.3	0.3	0.7	-0.8	-1.1	-0.6	-0.9
Type 2 Diabetes (T2D) (2018)	0.2	0.5	1.4	-0.5	-0.2	0.1	-0.2	-1.2	0.3	-0.7	-1.1
Neuroticism	0.2	0.5	1.4	-0.7	0.9	0.7	-0.6	-1.2	-0.2	0.1	-0.8
Medication: Co-codamol	0.2	0.2	0.5	-0.4	0.6	-0.4	-0.5	-0.7	0.3	-0.4	-0.3
Diabetes (mother)	0.2	0.2	0.9	0.6	-0.1	0.1	-0.0	1.0	-0.6	-0.0	0.0
Trunk fat percentage	0.2	0.8	2.9	0.8	0.7	1.7	-0.9	0.5	0.8	-0.2	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.5	0.7	0.4	0.2	0.7	0.4	0.5	0.4	0.4
Medication: Levothyroxine sodium	0.2	0.3	1.1	-0.5	-0.2	-0.8	0.3	-0.0	0.5	-1.1	-0.4
Forced vital capacity (FVC)	0.2	0.6	2.9	0.7	0.2	0.8	1.7	-0.1	-0.4	0.7	0.5
Qualifications: None of the above	0.2	0.5	2.4	0.2	0.3	0.7	-0.2	1.6	-0.8	-0.4	-0.4
Allergy	0.2	0.5	1.0	0.4	0.4	0.8	0.7	0.9	0.3	0.9	1.0
Diabetes (self-reported)	0.2	0.4	1.1	0.6	0.7	0.6	-1.0	-0.1	0.8	-0.0	0.0
Falls in the last year	0.2	0.2	0.4	0.3	-0.6	-0.6	-0.5	0.4	-0.0	0.3	0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	2.4	0.8	0.4	1.0	1.6	0.2	-0.4	0.4	0.6
Pulse rate	0.2	0.4	1.5	-0.1	0.6	0.4	1.2	-0.4	0.6	0.6	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	3.3	0.6	0.5	1.1	1.8	-0.1	-0.3	0.4	0.4
Exposure to tobacco smoke at home	0.2	0.3	0.5	0.5	-0.7	-0.5	0.6	0.5	-0.3	0.3	0.4
Breastfed as a baby	0.2	0.2	0.8	-0.0	-0.8	-0.9	0.2	0.2	-0.2	0.3	0.3
Tense / ‘highly strung’	0.2	0.4	1.8	-0.4	0.5	-0.5	1.3	-0.2	0.0	0.7	0.2
Hair/balding pattern: Pattern 4	0.2	0.5	1.7	1.0	0.1	0.7	-1.3	-0.2	0.3	0.4	0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.8	0.4	0.6	0.3	0.9	-0.6	0.6	0.5	0.3
Gout (self-reported)	0.2	0.2	0.6	-0.3	0.6	0.4	0.6	0.6	-0.8	-0.0	-0.3
Forced vital capacity (FVC), Best measure	0.2	0.6	3.2	0.3	0.1	0.8	1.8	-0.6	-0.5	0.4	0.1
Body fat percentage	0.2	0.9	3.0	1.0	0.9	1.7	-0.9	0.8	0.9	-0.1	0.6
Qualifications: College or University degree	0.2	0.7	1.5	1.0	0.8	0.7	0.2	0.9	0.7	1.2	0.8
Emphysema/chronic bronchitis	0.2	0.2	0.4	0.6	-0.7	0.2	0.5	-0.1	-0.7	-0.0	0.2
Medication: Omeprazole	0.2	0.3	1.1	-0.4	0.3	-0.4	-0.2	-0.6	-0.3	-1.1	-0.4
Illnesses of father: Heart disease	0.2	0.3	0.7	-0.1	0.7	0.4	0.5	-0.8	-0.4	-0.5	-0.5
Mood swings	0.2	0.3	0.8	-0.2	0.8	0.9	0.6	-0.4	0.3	0.2	-0.3
Diabetes diagnosed by doctor	0.2	0.4	1.1	-0.4	0.2	-0.4	-1.0	-0.9	0.3	-0.6	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.7	-0.1	0.3	-0.8	-0.8	-0.1	-0.1	0.2	-0.1
Qualifications: nursing, teaching	0.2	0.3	0.4	0.5	-0.2	-0.6	0.7	-0.4	0.3	0.6	0.6
Financial situation satisfaction	0.2	0.2	0.5	0.5	0.6	0.2	0.4	-0.2	0.4	0.7	0.4
Commuting to job workplace: Public transport	0.2	0.2	0.9	0.3	0.8	1.0	-0.1	-0.3	-0.3	-0.2	-0.2
Eye problems/disorders: Glaucoma	0.2	0.3	0.5	-0.4	0.3	0.6	0.6	-0.7	0.7	0.4	0.1
Vascular/heart problems diagnosed by doctor	0.2	0.7	1.4	1.1	0.7	-0.0	0.2	0.5	0.9	1.1	1.2
Ulcerative Colitis (UC)	0.1	0.2	0.6	-0.3	-0.2	0.2	0.2	-0.7	-0.5	0.7	-0.0
Crohns Disease (2012)	0.1	0.2	0.7	-0.7	0.0	0.4	0.2	-0.8	-0.3	0.5	-0.4
Neuroticism (2016)	0.1	0.1	0.3	-0.1	0.1	0.1	-0.3	-0.6	0.5	0.6	0.2
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.4	0.0	0.0	0.0	0.0	0.0	0.0	-0.7	-0.3
Heel T-Score	0.1	0.6	1.4	-0.5	1.2	1.1	0.1	-0.9	0.2	-1.0	-0.5
Systolic Blood Pressure	0.1	0.3	0.6	-0.6	-0.5	-0.8	0.2	0.3	-0.1	-0.4	-0.7
Respiratory disease	0.1	0.2	0.4	0.4	-0.3	-0.1	-0.1	-0.7	-0.6	-0.4	-0.1
Lung FEV1/FVC ratio	0.1	0.4	1.0	-0.8	-0.7	-0.5	0.7	-0.2	-0.3	-1.0	-0.8
Chronotype (morning person)	0.1	0.3	1.5	0.4	0.2	1.2	0.6	0.4	0.5	-0.0	-0.3
Tanning	0.1	1.1	4.4	0.5	-2.1	-0.1	-1.2	1.4	-1.0	-0.0	0.2
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	-0.2	0.3	0.3	-0.2	0.2	0.2	0.4	-0.2
Systolic blood pressure, automated reading	0.1	0.2	0.4	-0.4	-0.0	-0.5	0.6	0.5	0.2	0.5	0.0
Townsend deprivation index at recruitment	0.1	0.1	0.5	0.1	-0.5	0.2	-0.7	-0.1	0.0	0.1	0.1
Average weekly fortified wine intake	0.1	0.1	0.4	0.6	-0.1	-0.2	-0.4	0.3	0.3	0.4	0.4
Maternal smoking around birth	0.1	0.1	0.3	0.3	0.5	0.5	0.4	0.2	0.4	0.3	0.2
High blood pressure	0.1	0.2	0.6	-0.7	-0.2	0.1	-0.0	-0.3	-0.4	-0.8	-0.7
Alcohol usually taken with meals	0.1	0.2	0.6	0.5	0.4	-0.0	-0.5	0.7	0.6	-0.0	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.3	0.0	-0.0	0.3	0.1	-0.5	0.0	0.6	-0.1
Financial difficulties in last 2 years	0.1	0.2	0.8	-0.2	0.3	0.1	0.4	0.2	-0.4	-0.9	-0.3
Asthma	0.1	0.2	1.2	1.1	-0.2	0.5	-0.4	0.0	-0.3	0.1	0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	0.7	-0.5	-0.1	-0.7	0.5	0.4	0.5	-0.9	-0.4
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.4	0.1	0.1	0.2	0.1	-0.5	-0.6	-0.0	0.0
Wheeze or whistling in the chest in last year	0.1	0.1	0.5	0.4	0.2	0.1	0.4	0.3	-0.7	-0.0	0.4
Medication: Blood pressure	0.1	0.2	0.5	-0.7	-0.4	-0.2	-0.6	0.6	-0.2	-0.5	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.7	0.3	-0.7	-0.0	-0.8	0.2	0.0	0.0	-0.2
Had major operations	0.1	0.2	0.6	-0.2	0.4	0.8	-0.3	-0.3	-0.0	-0.5	-0.3
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.5	0.4	0.2	0.0	0.1	0.4	0.7	0.3	0.4
Asthma (self-reported)	0.1	0.2	0.4	0.6	-0.5	0.3	-0.6	-0.4	-0.6	-0.3	-0.3
Guilty feelings	0.1	0.1	0.3	-0.5	0.2	0.1	-0.0	-0.5	0.2	0.6	0.1
Mother’s age at death	0.1	0.1	0.3	-0.1	-0.6	-0.1	-0.3	-0.1	-0.2	-0.3	-0.3
Illnesses of father: High blood pressure	0.1	0.1	0.4	0.2	0.1	0.3	0.2	0.6	0.0	-0.2	0.1
Age started oral contraceptive pill	0.1	0.2	0.7	-0.3	0.8	0.5	-0.3	-0.0	0.0	-0.2	-0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.6	1.3	0.7	0.6	-0.2	1.0	1.1	0.6	0.6	0.9
Pulse rate, automated reading	0.0	0.1	0.2	0.1	0.5	0.4	0.0	0.0	-0.2	-0.3	-0.2
Knee pain experienced in last month	0.0	0.1	0.2	-0.2	0.0	-0.3	0.5	0.1	0.3	-0.2	-0.3
Hypertension (Self-reported)	0.0	0.1	0.3	-0.4	0.2	0.4	0.0	-0.2	-0.2	-0.5	-0.5

Hub : Genes

VRK3

Models

Trait associations