[Hub]/) : Traits : Sitting height : ← →

chr6:33,662,667-36,897,763

Best TWAS P=3.41e-42 · Best GWAS P=3.1e-50 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C6orf106	0.29	0.21	bslmm	382	0.23	6.9e-28	12.7	10.5	1.4e-25	-0.07	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FANCE	0.03	0.02	bslmm	420	0.01	1.7e-02	-6.4	-8.7	4.6e-18	0.08	0.37	0.04	TRUE
3	CommonMind	Brain Pre-frontal Cortex	PACSIN1	0.07	0.01	lasso	6	0.02	1.1e-03	13.0	10.8	3.8e-27	0.16	0.33	0.03	TRUE
4	CommonMind	Brain Pre-frontal Cortex	RPL10A	0.21	0.09	enet	30	0.11	2.6e-13	-5.5	-6.5	1.1e-10	-0.01	1.00	0.00	FALSE
5	GTEx	Adipose Subcutaneous	RPL10A	0.06	0.02	enet	27	0.03	2.6e-03	-7.0	-6.0	2.7e-09	-0.10	0.32	0.03	FALSE
6	GTEx	Artery Aorta	RPL10A	0.20	0.12	lasso	5	0.11	8.8e-07	-5.5	-6.0	1.9e-09	-0.04	0.96	0.00	FALSE
7	GTEx	Artery Tibial	C6orf106	0.07	0.02	lasso	4	0.02	8.8e-03	-3.3	5.6	2.1e-08	-0.13	0.10	0.05	TRUE
8	GTEx	Artery Tibial	RPL10A	0.11	0.08	lasso	2	0.09	1.5e-07	-5.3	-6.4	1.6e-10	-0.08	1.00	0.00	FALSE
9	GTEx	Brain Caudate basal ganglia	SNRPC	0.19	0.15	lasso	3	0.06	7.7e-03	4.2	-5.4	6.9e-08	-0.11	0.38	0.17	FALSE
10	GTEx	Brain Cerebellar Hemisphere	UHRF1BP1	0.22	0.16	lasso	12	0.15	1.0e-04	4.2	5.5	5.1e-08	0.11	0.20	0.55	FALSE
11	GTEx	Brain Cortex	C6orf106	0.22	0.07	enet	16	0.10	1.1e-03	13.0	11.9	8.1e-33	0.26	0.51	0.03	FALSE
12	GTEx	Brain Frontal Cortex BA9	TAF11	0.25	0.01	lasso	10	0.00	2.7e-01	-3.9	-5.2	1.8e-07	0.00	0.07	0.06	FALSE
13	GTEx	Brain Frontal Cortex BA9	RPS10	0.21	0.08	lasso	3	0.06	8.6e-03	2.9	5.4	6.5e-08	-0.05	0.12	0.05	FALSE
14	GTEx	Cells EBV-transformed lymphocytes	BRPF3	0.24	0.01	enet	26	0.00	4.2e-01	4.2	-5.2	2.4e-07	-0.11	0.04	0.42	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	C6orf106	0.20	0.00	lasso	5	0.00	2.7e-01	10.0	8.3	1.1e-16	0.08	0.07	0.05	FALSE
16	GTEx	Cells Transformed fibroblasts	TEAD3	0.36	0.29	enet	27	0.32	8.4e-25	3.2	-5.7	1.2e-08	-0.09	1.00	0.00	FALSE
17	GTEx	Cells Transformed fibroblasts	UHRF1BP1	0.34	0.32	enet	44	0.31	2.4e-23	4.2	5.4	5.4e-08	0.15	1.00	0.00	FALSE
18	GTEx	Cells Transformed fibroblasts	MAPK13	0.12	0.05	enet	20	0.05	7.5e-05	5.7	-5.1	2.8e-07	-0.11	0.49	0.39	FALSE
19	GTEx	Cells Transformed fibroblasts	NUDT3	0.11	0.03	lasso	3	0.02	9.2e-03	7.3	-6.6	5.0e-11	-0.40	0.24	0.03	TRUE
20	GTEx	Colon Transverse	C6orf106	0.15	0.05	lasso	1	0.03	1.5e-02	9.1	9.1	7.5e-20	-0.03	0.17	0.04	FALSE
21	GTEx	Colon Transverse	RPL10A	0.12	0.05	lasso	4	0.05	2.5e-03	-5.3	-6.4	1.2e-10	-0.06	0.28	0.05	FALSE
22	GTEx	Esophagus Mucosa	UHRF1BP1	0.14	0.15	enet	28	0.17	1.3e-11	3.7	5.2	1.6e-07	0.14	1.00	0.00	FALSE
23	GTEx	Esophagus Mucosa	MAPK13	0.34	0.29	lasso	5	0.38	2.3e-26	-4.5	5.8	6.9e-09	0.10	1.00	0.00	FALSE
24	GTEx	Esophagus Mucosa	RPL10A	0.14	0.10	enet	17	0.09	2.1e-06	-5.3	-8.4	4.6e-17	-0.12	0.94	0.01	TRUE
25	GTEx	Esophagus Muscularis	MAPK13	0.13	0.09	enet	26	0.08	1.5e-05	3.0	5.2	1.9e-07	0.08	0.27	0.69	FALSE
26	GTEx	Esophagus Muscularis	RPL10A	0.31	0.19	lasso	5	0.18	4.6e-11	-5.5	-5.6	1.9e-08	-0.01	1.00	0.00	TRUE
27	GTEx	Esophagus Muscularis	NUDT3	0.12	0.00	lasso	7	0.02	3.2e-02	5.8	-5.5	3.0e-08	-0.13	0.14	0.08	TRUE
28	GTEx	Liver	UHRF1BP1	0.13	0.04	lasso	3	0.05	1.8e-02	4.3	6.7	2.5e-11	0.09	0.16	0.12	FALSE
29	GTEx	Muscle Skeletal	SNRPC	0.03	0.02	lasso	3	0.02	8.3e-03	4.2	-6.1	1.2e-09	-0.13	0.08	0.81	FALSE
30	GTEx	Muscle Skeletal	C6orf106	0.08	0.06	lasso	4	0.06	7.1e-07	5.9	-7.5	7.4e-14	-0.10	0.98	0.00	FALSE
31	GTEx	Nerve Tibial	DEF6	0.15	0.00	lasso	8	0.00	1.6e-01	-4.1	5.4	8.4e-08	-0.01	0.18	0.05	FALSE
32	GTEx	Nerve Tibial	C6orf106	0.11	0.07	enet	17	0.07	1.3e-05	13.3	12.9	3.3e-38	0.03	0.71	0.01	FALSE
33	GTEx	Ovary	MAPK13	0.23	-0.01	enet	40	0.02	8.7e-02	3.2	6.7	2.1e-11	0.06	0.05	0.46	FALSE
34	GTEx	Pancreas	MAPK13	0.20	0.14	lasso	5	0.16	3.4e-07	4.2	5.8	8.7e-09	0.12	0.42	0.48	FALSE
35	GTEx	Pancreas	C6orf106	0.14	0.11	enet	11	0.13	2.8e-06	5.9	9.5	3.0e-21	0.10	0.86	0.01	FALSE
36	GTEx	Skin Not Sun Exposed Suprapubic	TEAD3	0.15	0.06	lasso	5	0.08	2.5e-05	-5.2	-6.2	6.9e-10	-0.09	0.78	0.01	FALSE
37	GTEx	Skin Not Sun Exposed Suprapubic	MAPK13	0.20	0.05	lasso	5	0.08	2.8e-05	-4.5	6.7	2.0e-11	0.10	0.10	0.89	TRUE
38	GTEx	Skin Sun Exposed Lower leg	SRPK1	0.14	0.00	enet	27	0.02	1.2e-02	-1.4	6.3	2.7e-10	0.14	0.23	0.07	TRUE
39	GTEx	Skin Sun Exposed Lower leg	MAPK13	0.23	0.20	enet	7	0.23	4.8e-19	-4.5	5.4	7.1e-08	0.11	1.00	0.00	FALSE
40	GTEx	Skin Sun Exposed Lower leg	C6orf106	0.09	0.04	enet	25	0.02	4.6e-03	-2.0	8.8	1.3e-18	0.04	0.38	0.02	FALSE
41	GTEx	Small Intestine Terminal Ileum	UHRF1BP1	0.20	0.03	lasso	5	0.00	3.4e-01	4.2	5.5	3.4e-08	0.13	0.14	0.10	FALSE
42	GTEx	Testis	ZNF76	0.15	0.14	enet	8	0.12	4.4e-06	-5.3	5.2	2.0e-07	-0.02	0.94	0.00	FALSE
43	GTEx	Testis	MAPK13	0.16	0.16	lasso	2	0.16	1.1e-07	-4.4	5.2	1.7e-07	0.11	0.77	0.10	FALSE
44	GTEx	Thyroid	C6orf106	0.09	0.01	enet	29	0.01	1.1e-01	13.0	9.7	3.1e-22	-0.10	0.10	0.04	FALSE
45	GTEx	Thyroid	RPL10A	0.16	0.09	lasso	11	0.07	8.9e-06	-6.8	-6.7	1.7e-11	-0.13	0.89	0.00	FALSE
46	GTEx	Uterus	UHRF1BP1	0.20	0.03	lasso	4	0.07	1.8e-02	4.3	7.8	8.7e-15	0.13	0.09	0.23	FALSE
47	GTEx	Vagina	UHRF1BP1	0.31	0.05	lasso	8	0.04	5.0e-02	4.3	5.6	1.9e-08	0.12	0.10	0.42	FALSE
48	METSIM	Adipose	C6orf106	0.04	0.02	blup	381	0.02	7.7e-04	7.3	7.6	2.7e-14	-0.13	0.43	0.02	FALSE
49	METSIM	Adipose	SRPK1	0.06	0.01	blup	438	0.04	3.9e-07	-1.1	-5.5	4.1e-08	-0.13	0.70	0.05	FALSE
50	NTR	Blood	C6orf106	0.03	0.02	lasso	6	0.02	7.2e-07	13.0	13.3	3.3e-40	0.05	1.00	0.00	TRUE
51	ROSMAP	Brain Pre-frontal Cortex	PACSIN1	0.09	0.00	blup	359	0.02	4.5e-04	12.7	12.1	6.4e-34	0.27	0.18	0.07	FALSE
52	ROSMAP	Brain Pre-frontal Cortex	C6orf106	0.30	0.26	bslmm	372	0.33	9.3e-44	13.0	11.5	1.5e-30	0.00	1.00	0.00	FALSE
53	YFS	Blood	SNRPC	0.02	0.03	lasso	5	0.02	3.0e-08	6.8	-6.9	7.0e-12	-0.12	0.98	0.02	FALSE
54	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RPL10A	0.03	0.00	blup	54	0.02	6.0e-03	-5.1	-5.6	1.7e-08	0.03	0.04	0.20	FALSE
55	The Cancer Genome Atlas	Breast Invasive Carcinoma	MAPK13	0.02	0.02	lasso	2	0.01	1.1e-03	5.6	6.0	1.6e-09	0.09	0.03	0.75	FALSE
56	The Cancer Genome Atlas	Colon Adenocarcinoma	MAPK13	0.12	0.07	blup	43	0.09	8.5e-06	-4.5	5.3	1.0e-07	0.11	0.51	0.31	FALSE
57	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C6orf106	0.09	0.03	lasso	5	0.05	3.6e-06	-3.6	5.8	5.2e-09	-0.03	0.32	0.04	FALSE
58	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf106	0.04	0.01	blup	68	0.01	2.4e-02	12.9	11.7	1.4e-31	0.08	0.00	0.84	FALSE
59	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RPL10A	0.07	0.07	lasso	2	0.06	9.9e-08	-5.3	-6.1	1.4e-09	-0.04	0.81	0.19	FALSE
60	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf106	0.04	0.05	lasso	4	0.03	8.1e-05	12.9	12.7	5.3e-37	0.09	0.07	0.93	FALSE
61	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ZNF76	0.08	0.05	lasso	10	0.07	4.9e-04	-7.1	-5.5	3.7e-08	0.06	0.05	0.39	FALSE
62	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf106	0.03	0.03	lasso	3	0.01	7.6e-03	7.3	9.8	8.6e-23	0.00	0.05	0.62	TRUE
63	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf81	0.05	0.00	blup	43	0.02	8.9e-04	4.9	-5.6	2.2e-08	0.03	0.03	0.03	FALSE
64	The Cancer Genome Atlas	Lung Adenocarcinoma	RPL10A	0.02	0.02	lasso	2	0.02	3.8e-03	-5.8	-5.8	6.1e-09	-0.01	0.07	0.14	FALSE
65	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf106	0.14	0.07	enet	6	0.06	1.0e-04	13.0	13.6	3.4e-42	0.08	0.01	0.96	TRUE
66	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CLPS	0.26	0.08	enet	14	0.10	4.9e-07	2.9	-5.3	1.0e-07	-0.02	0.02	0.06	TRUE
67	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPL10A	0.09	0.03	enet	19	0.07	1.1e-07	-5.5	-6.8	1.0e-11	0.01	0.09	0.90	FALSE
68	The Cancer Genome Atlas	Thyroid Carcinoma	C6orf106	0.08	0.00	enet	15	0.05	2.5e-05	-2.9	10.3	4.5e-25	-0.05	0.03	0.28	FALSE
69	The Cancer Genome Atlas	Thyroid Carcinoma	MAPK13	0.07	0.06	lasso	6	0.06	1.5e-06	-4.5	5.8	8.3e-09	0.12	0.68	0.19	FALSE
70	The Cancer Genome Atlas	Thyroid Carcinoma	RPL10A	0.05	0.07	enet	4	0.04	1.2e-04	-5.5	-6.3	2.5e-10	-0.03	0.76	0.05	FALSE