[Hub]/) : Traits : Arm fat percentage (right) : ← →

chr11:46,180,005-48,783,497

Best TWAS P=1.52e-40 · Best GWAS P=1.68e-39 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
98	The Cancer Genome Atlas	Lung Adenocarcinoma	C1QTNF4	0.03	0.02	blup	15	0.02	1.3e-03	13.02	-13.3	1.5e-40	-0.97	0.00	0.97	TRUE
33	GTEx	Liver	C1QTNF4	0.25	0.14	enet	16	0.20	2.3e-06	13.02	-12.2	1.9e-34	-0.84	0.02	0.97	TRUE
14	GTEx	Breast Mammary Tissue (Female)	MADD	0.13	0.04	lasso	3	0.05	1.3e-02	10.49	10.9	7.1e-28	0.81	0.05	0.32	TRUE
30	GTEx	Heart Left Ventricle	MADD	0.14	0.01	enet	17	0.05	7.0e-04	-4.41	9.6	6.5e-22	0.70	0.02	0.95	TRUE
55	METSIM	Adipose	MYBPC3	0.11	0.10	enet	26	0.11	1.0e-15	10.51	-9.6	8.0e-22	-0.81	0.32	0.68	TRUE
100	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MADD	0.16	0.05	blup	64	0.08	2.2e-09	-1.31	5.5	4.9e-08	0.10	0.98	0.00	TRUE
62	ROSMAP	Brain Pre-frontal Cortex	PACSIN3	0.11	0.00	bslmm	292	0.04	1.8e-06	1.99	5.2	2.3e-07	0.12	0.16	0.03	TRUE
6	GTEx	Artery Aorta	C1QTNF4	0.09	0.10	lasso	1	0.08	3.2e-05	13.02	-13.0	9.4e-39	-1.00	0.00	0.99	FALSE
24	GTEx	Esophagus Mucosa	C1QTNF4	0.10	0.11	lasso	1	0.10	5.0e-07	13.02	-13.0	9.4e-39	-1.00	0.00	1.00	FALSE
31	GTEx	Heart Left Ventricle	C1QTNF4	0.10	0.11	lasso	1	0.09	1.1e-05	13.02	-13.0	9.4e-39	-1.00	0.00	0.99	FALSE
77	The Cancer Genome Atlas	Colon Adenocarcinoma	C1QTNF4	0.12	0.12	lasso	1	0.12	1.6e-07	13.02	-13.0	9.4e-39	-1.00	0.00	1.00	FALSE
36	GTEx	Muscle Skeletal	C1QTNF4	0.09	0.14	lasso	3	0.13	9.9e-13	13.02	-13.0	2.2e-38	-0.98	0.00	1.00	FALSE
46	GTEx	Skin Sun Exposed Lower leg	C1QTNF4	0.25	0.22	lasso	12	0.23	4.2e-19	13.02	-12.9	3.4e-38	-0.95	0.00	1.00	FALSE
19	GTEx	Cells Transformed fibroblasts	NDUFS3	0.08	0.01	lasso	2	0.01	3.3e-02	13.15	-12.8	1.3e-37	-0.98	0.00	0.98	FALSE
81	The Cancer Genome Atlas	Esophageal Carcinoma	C1QTNF4	0.39	0.33	blup	15	0.35	6.1e-12	13.02	-12.8	1.4e-37	-0.98	0.00	1.00	FALSE
5	GTEx	Adipose Subcutaneous	C1QTNF4	0.16	0.22	lasso	4	0.22	2.5e-18	13.15	-12.8	2.8e-37	-0.98	0.00	1.00	FALSE
47	GTEx	Spleen	C1QTNF4	0.31	0.28	enet	29	0.34	1.8e-09	11.43	-12.7	5.3e-37	-0.89	0.08	0.92	FALSE
29	GTEx	Heart Atrial Appendage	C1QTNF4	0.26	0.14	lasso	9	0.17	3.9e-08	13.02	-12.7	5.7e-37	-0.95	0.02	0.98	FALSE
20	GTEx	Colon Transverse	C1QTNF4	0.07	0.02	lasso	6	0.03	2.0e-02	13.15	-12.7	8.6e-37	-0.96	0.01	0.96	FALSE
15	GTEx	Cells Transformed fibroblasts	FNBP4	0.11	0.05	lasso	8	0.08	1.6e-06	-11.34	12.5	5.7e-36	0.88	0.04	0.96	FALSE
86	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1QTNF4	0.12	0.14	enet	4	0.16	6.5e-18	11.57	-12.5	6.4e-36	-0.95	0.03	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FAM180B	0.07	0.08	lasso	3	0.08	9.1e-10	13.02	12.4	2.8e-35	0.95	0.02	0.98	FALSE
71	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C1QTNF4	0.06	0.07	lasso	2	0.06	4.9e-06	11.66	-12.4	4.4e-35	-0.93	0.01	0.99	FALSE
79	The Cancer Genome Atlas	Colon Adenocarcinoma	NUP160	0.05	0.05	blup	44	0.05	7.7e-04	-11.38	12.3	5.9e-35	0.82	0.03	0.74	FALSE
27	GTEx	Esophagus Muscularis	C1QTNF4	0.10	0.05	enet	23	0.06	1.4e-04	13.15	-12.3	9.9e-35	-0.93	0.01	0.99	FALSE
105	The Cancer Genome Atlas	Stomach Adenocarcinoma	C1QTNF4	0.06	0.04	lasso	4	0.03	4.3e-03	11.61	-12.2	3.7e-34	-0.92	0.00	0.92	FALSE
41	GTEx	Nerve Tibial	C1QTNF4	0.20	0.23	enet	12	0.23	1.7e-16	13.02	-12.1	8.3e-34	-0.96	0.00	1.00	FALSE
59	ROSMAP	Brain Pre-frontal Cortex	MTCH2	0.35	0.40	enet	9	0.40	4.7e-56	11.57	12.0	2.5e-33	0.91	1.00	0.00	FALSE
107	The Cancer Genome Atlas	Thyroid Carcinoma	C1QTNF4	0.04	0.01	blup	15	0.03	7.9e-04	13.02	-11.9	1.2e-32	-0.89	0.00	0.95	FALSE
103	The Cancer Genome Atlas	Prostate Adenocarcinoma	NUP160	0.03	0.02	enet	7	0.02	6.3e-03	10.88	11.9	1.5e-32	0.83	0.02	0.82	FALSE
60	ROSMAP	Brain Pre-frontal Cortex	FNBP4	0.04	0.04	lasso	3	0.04	8.2e-06	-11.38	11.8	3.4e-32	0.69	0.95	0.05	FALSE
34	GTEx	Lung	C1QTNF4	0.18	0.15	lasso	6	0.13	3.2e-10	10.49	-11.8	5.7e-32	-0.91	0.09	0.91	FALSE
58	NTR	Blood	MTCH2	0.02	0.04	lasso	1	0.04	1.3e-11	11.72	-11.7	1.0e-31	-0.88	0.90	0.10	FALSE
89	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1QTNF4	0.13	0.16	lasso	1	0.16	3.1e-09	11.70	-11.7	1.2e-31	-0.88	0.15	0.85	FALSE
12	GTEx	Brain Cortex	C1QTNF4	0.26	0.04	lasso	8	0.02	1.2e-01	-11.30	-11.6	2.9e-31	-0.80	0.02	0.58	FALSE
82	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1QTNF4	0.06	0.08	lasso	3	0.08	7.5e-09	11.57	-11.6	2.9e-31	-0.88	0.04	0.96	FALSE
93	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTCH2	0.11	0.11	lasso	2	0.10	6.4e-12	11.57	11.6	4.4e-31	0.87	0.09	0.91	FALSE
96	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C1QTNF4	0.19	0.19	lasso	3	0.19	3.2e-09	11.57	-11.6	4.5e-31	-0.87	0.09	0.91	FALSE
35	GTEx	Muscle Skeletal	MTCH2	0.05	0.03	enet	15	0.04	1.5e-04	10.88	11.6	6.9e-31	0.84	0.05	0.94	FALSE
52	GTEx	Whole Blood	C1QTNF4	0.09	0.05	lasso	3	0.03	1.4e-03	11.45	-11.5	9.8e-31	-0.86	0.18	0.72	FALSE
44	GTEx	Skin Not Sun Exposed Suprapubic	C1QTNF4	0.32	0.18	enet	33	0.20	5.2e-11	13.02	-11.5	9.9e-31	-0.90	0.00	1.00	FALSE
49	GTEx	Testis	C1QTNF4	0.14	0.12	lasso	4	0.11	1.6e-05	-11.38	-11.4	3.3e-30	-0.73	0.28	0.67	FALSE
25	GTEx	Esophagus Muscularis	MTCH2	0.09	0.04	lasso	6	0.02	1.8e-02	11.72	11.4	7.0e-30	0.78	0.26	0.53	FALSE
54	METSIM	Adipose	C1QTNF4	0.24	0.31	lasso	7	0.31	1.2e-46	11.57	-11.3	9.0e-30	-0.86	1.00	0.00	FALSE
18	GTEx	Cells Transformed fibroblasts	C1QTNF4	0.13	0.11	enet	19	0.12	5.2e-09	11.72	-10.9	1.5e-27	-0.84	0.03	0.97	FALSE
92	The Cancer Genome Atlas	Brain Lower Grade Glioma	MADD	0.08	0.01	lasso	5	0.05	3.1e-06	10.49	10.8	4.5e-27	0.62	0.01	0.95	FALSE
65	YFS	Blood	FNBP4	0.02	0.01	bslmm	301	0.01	8.9e-05	-9.20	10.7	9.5e-27	0.78	0.03	0.95	FALSE
97	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PSMC3	0.09	0.07	blup	39	0.06	8.7e-04	10.48	10.6	2.8e-26	0.85	0.01	0.98	FALSE
90	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PSMC3	0.07	0.07	enet	7	0.06	1.4e-04	10.53	10.6	3.5e-26	0.82	0.01	0.98	FALSE
78	The Cancer Genome Atlas	Colon Adenocarcinoma	KBTBD4	0.14	0.01	blup	13	0.02	1.6e-02	-11.53	10.6	3.7e-26	0.90	0.00	0.53	FALSE
48	GTEx	Testis	MTCH2	0.17	0.16	lasso	3	0.16	1.0e-07	10.51	10.5	5.8e-26	0.83	0.52	0.48	FALSE
64	ROSMAP	Brain Pre-frontal Cortex	C1QTNF4	0.05	0.06	blup	281	0.06	1.7e-08	10.52	-10.3	4.3e-25	-0.86	0.10	0.90	FALSE
74	The Cancer Genome Atlas	Breast Invasive Carcinoma	MADD	0.11	0.03	enet	14	0.06	1.4e-11	-6.05	10.3	8.6e-25	0.56	0.04	0.96	FALSE
13	GTEx	Breast Mammary Tissue	C1QTNF4	0.10	0.06	lasso	2	0.03	8.5e-03	10.51	-10.2	1.2e-24	-0.82	0.10	0.67	FALSE
11	GTEx	Brain Cortex	MTCH2	0.21	0.19	lasso	6	0.16	4.0e-05	11.43	10.2	2.7e-24	0.79	0.35	0.18	FALSE
68	YFS	Blood	PSMC3	0.02	0.01	blup	289	0.01	2.8e-05	13.15	9.9	2.7e-23	0.84	0.00	0.99	FALSE
69	YFS	Blood	PTPMT1	0.03	0.01	lasso	5	0.01	3.2e-04	-11.49	-9.9	3.1e-23	-0.67	0.27	0.61	FALSE
42	GTEx	Pituitary	MADD	0.42	0.32	lasso	6	0.39	8.9e-11	-5.67	9.9	3.5e-23	0.60	0.25	0.63	FALSE
17	GTEx	Cells Transformed fibroblasts	PSMC3	0.07	0.00	enet	13	0.02	2.3e-02	-4.07	9.8	7.6e-23	0.83	0.03	0.77	FALSE
10	GTEx	Brain Cerebellum	MADD	0.21	0.00	enet	13	0.11	3.3e-04	-4.69	9.8	1.8e-22	0.63	0.07	0.68	FALSE
75	The Cancer Genome Atlas	Breast Invasive Carcinoma	MYBPC3	0.02	0.01	blup	43	0.01	3.4e-03	10.49	-9.6	1.0e-21	-0.74	0.01	0.97	FALSE
95	The Cancer Genome Atlas	Brain Lower Grade Glioma	PSMC3	0.10	0.05	blup	39	0.08	3.7e-09	10.51	9.4	7.7e-21	0.79	0.02	0.98	FALSE
85	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NUP160	0.08	0.03	blup	42	0.04	6.7e-05	11.48	9.2	3.0e-20	0.71	0.01	0.94	FALSE
3	CommonMind	Brain Pre-frontal Cortex	MTCH2	0.03	0.00	bslmm	299	0.00	1.1e-01	0.70	9.2	5.4e-20	0.68	0.07	0.53	FALSE
84	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MYBPC3	0.05	0.03	blup	43	0.04	6.0e-05	8.00	-9.0	3.4e-19	-0.71	0.01	0.98	FALSE
80	The Cancer Genome Atlas	Colon Adenocarcinoma	PSMC3	0.09	0.05	blup	39	0.05	1.0e-03	-6.31	8.8	1.6e-18	0.55	0.02	0.82	FALSE
4	GTEx	Adipose Subcutaneous	ACP2	0.08	0.03	enet	18	0.03	3.5e-03	-4.32	8.7	3.0e-18	0.73	0.08	0.78	FALSE
104	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMC3	0.02	0.02	blup	39	0.02	5.7e-03	10.51	8.6	6.9e-18	0.78	0.01	0.71	FALSE
61	ROSMAP	Brain Pre-frontal Cortex	ACP2	0.03	0.00	blup	295	0.02	1.5e-03	10.49	8.6	7.5e-18	0.72	0.06	0.86	FALSE
37	GTEx	Nerve Tibial	NR1H3	0.10	0.00	enet	24	0.08	4.7e-06	-1.53	-8.5	2.1e-17	-0.52	0.01	0.82	FALSE
56	METSIM	Adipose	PSMC3	0.06	0.03	enet	28	0.04	2.3e-06	5.02	8.4	5.7e-17	0.79	0.03	0.96	FALSE
94	The Cancer Genome Atlas	Brain Lower Grade Glioma	MYBPC3	0.03	0.01	blup	43	0.02	3.2e-03	10.48	-8.2	1.8e-16	-0.72	0.00	0.90	FALSE
99	The Cancer Genome Atlas	Lung Adenocarcinoma	MYBPC3	0.04	0.02	enet	10	0.04	2.9e-05	10.49	-8.1	3.9e-16	-0.68	0.01	0.98	FALSE
22	GTEx	Esophagus Mucosa	MADD	0.27	0.04	enet	18	0.12	4.1e-08	-4.73	8.1	8.0e-16	0.40	0.26	0.08	FALSE
73	The Cancer Genome Atlas	Breast Invasive Carcinoma	C1QTNF4	0.02	0.01	lasso	5	0.02	2.1e-04	-2.20	-7.9	2.3e-15	-0.74	0.01	0.83	FALSE
108	The Cancer Genome Atlas	Thyroid Carcinoma	MADD	0.07	0.00	enet	11	0.03	6.7e-04	-4.59	7.9	2.7e-15	0.36	0.05	0.13	FALSE
88	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMC3	0.05	0.04	lasso	3	0.05	3.8e-06	5.02	7.9	2.8e-15	0.73	0.01	0.98	FALSE
102	The Cancer Genome Atlas	Prostate Adenocarcinoma	MADD	0.15	0.04	enet	10	0.06	4.5e-07	-6.05	7.9	3.8e-15	0.30	0.20	0.03	FALSE
87	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MADD	0.20	0.07	enet	9	0.08	2.4e-09	-6.05	7.8	4.3e-15	0.32	0.92	0.01	FALSE
70	YFS	Blood	SPI1	0.65	0.18	enet	75	0.27	1.6e-87	10.45	-7.8	4.7e-15	-0.62	1.00	0.00	FALSE
7	GTEx	Brain Cerebellar Hemisphere	MADD	0.44	0.14	lasso	7	0.21	4.0e-06	-4.32	7.6	3.0e-14	0.50	0.33	0.19	FALSE
32	GTEx	Liver	PSMC3	0.15	0.09	lasso	4	0.07	5.9e-03	6.74	7.5	6.3e-14	0.59	0.09	0.10	FALSE
72	The Cancer Genome Atlas	Breast Invasive Carcinoma	ACP2	0.02	0.01	blup	44	0.02	2.7e-04	-4.69	7.4	9.9e-14	0.50	0.04	0.21	FALSE
53	METSIM	Adipose	ACP2	0.05	0.04	blup	302	0.06	1.7e-09	10.51	7.4	1.5e-13	0.67	0.35	0.65	FALSE
101	The Cancer Genome Atlas	Prostate Adenocarcinoma	AGBL2	0.04	0.03	blup	49	0.03	7.8e-04	-9.73	7.4	1.5e-13	0.41	0.18	0.07	FALSE
66	YFS	Blood	NR1H3	0.34	0.15	enet	66	0.24	3.1e-76	-4.39	7.3	2.3e-13	0.56	1.00	0.00	FALSE
16	GTEx	Cells Transformed fibroblasts	MADD	0.19	0.00	enet	17	0.09	3.3e-07	-4.89	7.3	2.7e-13	0.30	0.53	0.04	FALSE
40	GTEx	Nerve Tibial	SLC39A13	0.07	0.01	enet	14	0.02	7.6e-03	10.53	7.2	4.9e-13	0.70	0.13	0.34	FALSE
63	ROSMAP	Brain Pre-frontal Cortex	PSMC3	0.15	0.08	bslmm	285	0.10	5.1e-13	-3.16	7.0	2.3e-12	0.68	0.41	0.59	FALSE
45	GTEx	Skin Sun Exposed Lower leg	PSMC3	0.20	0.05	lasso	7	0.10	1.2e-08	-4.07	6.9	5.4e-12	0.68	0.68	0.29	FALSE
67	YFS	Blood	NUP160	0.02	0.01	blup	290	0.01	1.7e-04	11.46	6.8	9.2e-12	0.65	0.24	0.60	FALSE
76	The Cancer Genome Atlas	Breast Invasive Carcinoma	NUP160	0.03	0.01	blup	44	0.01	1.9e-03	10.86	6.8	9.3e-12	0.58	0.01	0.40	FALSE
83	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FNBP4	0.10	0.03	blup	45	0.05	7.7e-06	11.46	6.7	1.6e-11	0.51	0.01	0.97	FALSE
106	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MADD	0.21	0.04	blup	64	0.07	1.3e-03	-4.36	6.7	2.1e-11	0.28	0.07	0.05	FALSE
28	GTEx	Heart Atrial Appendage	ACP2	0.10	0.12	enet	7	0.10	2.7e-05	-5.12	6.6	3.3e-11	0.49	0.32	0.07	FALSE
39	GTEx	Nerve Tibial	CELF1	0.08	0.02	enet	15	0.06	4.3e-05	-10.12	6.6	3.7e-11	0.40	0.21	0.04	FALSE
57	NTR	Blood	ACP2	0.01	0.00	enet	7	0.01	2.5e-03	-4.59	6.4	1.6e-10	0.44	0.43	0.11	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MADD	0.32	0.17	bslmm	315	0.18	1.4e-21	-6.05	6.3	2.6e-10	0.19	1.00	0.00	FALSE
9	GTEx	Brain Cerebellar Hemisphere	RP11-750H9.5	0.17	0.25	lasso	6	0.21	3.5e-06	-6.31	6.3	2.8e-10	0.29	0.43	0.06	FALSE
91	The Cancer Genome Atlas	Brain Lower Grade Glioma	ACP2	0.09	0.04	enet	12	0.06	5.0e-07	-4.32	6.2	4.2e-10	0.56	0.60	0.38	FALSE
38	GTEx	Nerve Tibial	PTPRJ	0.05	0.03	enet	13	0.03	2.7e-03	-3.69	-6.1	1.2e-09	-0.50	0.19	0.08	FALSE
50	GTEx	Thyroid	MADD	0.11	0.00	enet	13	0.01	6.1e-02	-4.07	6.0	2.4e-09	0.25	0.06	0.04	FALSE
43	GTEx	Skin Not Sun Exposed Suprapubic	LRP4	0.13	0.00	lasso	7	0.02	3.5e-02	-0.46	-5.7	1.3e-08	-0.60	0.04	0.74	FALSE
26	GTEx	Esophagus Muscularis	MADD	0.13	0.07	enet	8	0.11	2.0e-07	-6.05	5.7	1.4e-08	0.17	0.73	0.01	FALSE
23	GTEx	Esophagus Mucosa	C11orf49	0.19	0.05	enet	21	0.12	3.2e-08	-4.57	-5.5	3.6e-08	-0.29	0.79	0.01	FALSE
8	GTEx	Brain Cerebellar Hemisphere	ACP2	0.29	0.05	enet	16	0.12	5.9e-04	-3.82	5.3	1.0e-07	0.44	0.09	0.10	FALSE
51	GTEx	Thyroid	ACP2	0.19	0.14	lasso	4	0.12	3.0e-09	-4.69	5.2	1.8e-07	0.34	1.00	0.00	FALSE
21	GTEx	Esophagus Gastroesophageal Junction	NUP160	0.18	0.02	enet	18	0.11	7.1e-05	-1.79	5.2	1.9e-07	0.29	0.27	0.05	FALSE