[Hub]/) : Traits : Arm fat mass (right) :

chr12:121,194,565-125,270,773

Best TWAS P=1.06e-19 · Best GWAS P=6.59e-23 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HIP1R 0.06 0.02 lasso 6 0.04 1.9e-05 -6.1 -5.7 1.2e-08 0.09 0.18 0.02 FALSE
2 GTEx Adipose Subcutaneous ZCCHC8 0.04 0.00 lasso 7 0.00 1.4e-01 5.6 6.1 8.0e-10 -0.31 0.17 0.10 TRUE
3 GTEx Adipose Subcutaneous CCDC92 0.23 0.04 enet 27 0.16 6.9e-13 -5.1 8.1 6.0e-16 -0.09 0.05 0.95 FALSE
4 GTEx Adipose Subcutaneous RP11-380L11.3 0.09 0.03 lasso 3 0.03 1.4e-03 6.2 8.3 1.1e-16 -0.07 0.03 0.96 FALSE
5 GTEx Adipose Visceral Omentum CCDC92 0.19 0.02 lasso 8 0.09 3.3e-05 6.3 9.1 1.1e-19 -0.12 0.03 0.96 TRUE
6 GTEx Adipose Visceral Omentum RP11-380L11.3 0.15 0.03 lasso 5 0.01 1.4e-01 6.0 8.8 1.0e-18 -0.08 0.03 0.82 FALSE
7 GTEx Artery Tibial RP11-380L11.4 0.14 0.12 lasso 4 0.12 2.2e-09 6.2 6.0 1.5e-09 -0.04 0.05 0.95 FALSE
8 GTEx Brain Putamen basal ganglia WDR66 0.25 0.01 enet 16 -0.01 5.6e-01 6.6 -5.5 4.5e-08 0.15 0.06 0.26 FALSE
9 GTEx Breast Mammary Tissue (Male) CCDC92 0.06 -0.01 lasso 3 0.00 4.3e-01 5.4 6.0 1.6e-09 -0.07 0.04 0.12 FALSE
10 GTEx Breast Mammary Tissue (Female) CCDC92 0.05 -0.01 enet 2 -0.01 6.2e-01 5.2 5.3 1.5e-07 -0.04 0.04 0.23 FALSE
11 GTEx Breast Mammary Tissue (Female) C12orf65 0.06 0.00 enet 13 -0.01 6.5e-01 -4.0 -6.0 1.6e-09 0.27 0.04 0.08 FALSE
12 GTEx Cells Transformed fibroblasts BCL7A 0.06 0.01 lasso 4 0.01 3.1e-02 4.2 -7.3 2.1e-13 0.24 0.09 0.05 TRUE
13 GTEx Colon Sigmoid RP11-380L11.4 0.21 0.12 lasso 3 0.08 1.1e-03 6.2 6.3 3.9e-10 -0.06 0.05 0.88 FALSE
14 GTEx Colon Transverse MLXIP 0.20 0.18 enet 23 0.14 5.8e-07 7.3 7.0 2.8e-12 -0.17 1.00 0.00 FALSE
15 GTEx Colon Transverse SNRNP35 0.18 0.02 lasso 8 0.04 6.5e-03 -4.2 6.8 1.5e-11 -0.16 0.07 0.16 FALSE
16 GTEx Esophagus Mucosa KDM2B 0.11 0.04 enet 22 0.10 4.1e-07 2.7 6.5 7.2e-11 -0.10 0.92 0.01 TRUE
17 GTEx Esophagus Mucosa CCDC92 0.11 0.02 lasso 4 0.02 1.9e-02 5.5 5.6 1.7e-08 -0.05 0.11 0.76 FALSE
18 GTEx Esophagus Mucosa HIP1R 0.21 0.05 lasso 5 0.07 1.5e-05 4.0 7.7 1.9e-14 -0.21 0.47 0.26 FALSE
19 GTEx Esophagus Muscularis RP11-380L11.4 0.27 0.29 lasso 8 0.27 1.0e-16 6.3 6.2 5.0e-10 -0.05 0.04 0.96 FALSE
20 GTEx Heart Atrial Appendage CCDC92 0.12 0.11 enet 9 0.11 1.1e-05 4.6 6.0 2.7e-09 -0.05 0.08 0.89 FALSE
21 GTEx Heart Atrial Appendage RP11-380L11.4 0.18 0.11 lasso 7 0.12 6.5e-06 6.3 7.1 1.5e-12 -0.07 0.04 0.96 FALSE
22 GTEx Heart Left Ventricle CCDC92 0.26 0.19 lasso 4 0.21 1.9e-11 5.5 6.8 9.2e-12 -0.06 0.11 0.89 FALSE
23 GTEx Lung CCDC92 0.14 0.00 enet 10 0.01 1.1e-01 6.6 6.8 1.4e-11 -0.08 0.02 0.90 FALSE
24 GTEx Lung RP11-380L11.4 0.07 0.07 lasso 3 0.07 8.2e-06 6.4 6.2 4.2e-10 -0.06 0.04 0.96 FALSE
25 GTEx Muscle Skeletal RSRC2 0.06 0.03 enet 7 0.04 9.6e-05 -3.5 -6.8 1.1e-11 0.43 0.25 0.48 FALSE
26 GTEx Nerve Tibial CCDC92 0.16 0.01 enet 6 0.04 6.7e-04 5.3 7.2 6.2e-13 -0.10 0.08 0.60 FALSE
27 GTEx Nerve Tibial KNTC1 0.12 0.05 lasso 5 0.05 1.9e-04 -6.5 -7.2 5.8e-13 0.31 0.53 0.03 FALSE
28 GTEx Prostate CCDC92 0.31 0.10 enet 42 0.11 9.0e-04 5.2 5.3 1.3e-07 -0.08 0.06 0.71 FALSE
29 GTEx Skin Sun Exposed Lower leg WDR66 0.19 0.10 lasso 5 0.08 5.5e-07 3.4 5.1 3.1e-07 -0.11 0.99 0.00 TRUE
30 GTEx Testis ABCB9 0.14 0.05 lasso 3 0.06 8.0e-04 6.8 -5.9 3.0e-09 0.22 0.25 0.05 FALSE
31 GTEx Thyroid CCDC92 0.06 0.03 lasso 3 0.02 1.1e-02 6.3 7.6 2.5e-14 -0.08 0.04 0.93 FALSE
32 GTEx Thyroid ZNF664 0.13 0.06 lasso 11 0.08 6.7e-07 5.2 -6.0 2.4e-09 0.04 0.06 0.94 FALSE
33 GTEx Whole Blood DDX55 0.13 0.04 enet 13 0.06 3.3e-06 -3.3 5.2 1.9e-07 -0.17 0.34 0.02 FALSE
34 METSIM Adipose ABCB9 0.04 0.03 enet 19 0.03 7.7e-05 -6.1 -7.7 1.1e-14 0.38 0.08 0.65 TRUE
35 METSIM Adipose CCDC92 0.10 0.01 bslmm 435 0.06 5.5e-10 -3.0 7.7 1.7e-14 -0.08 0.03 0.97 FALSE
36 METSIM Adipose CLIP1 0.03 0.01 bslmm 372 0.01 3.3e-03 -5.1 5.2 1.6e-07 -0.31 0.60 0.04 TRUE
37 METSIM Adipose MORN3 0.06 0.02 lasso 10 0.04 8.7e-07 4.8 5.6 2.5e-08 -0.05 0.95 0.00 FALSE
38 METSIM Adipose RP11-214K3.24 0.05 0.03 bslmm 444 0.02 2.7e-04 5.5 7.0 3.1e-12 -0.07 0.05 0.91 FALSE
39 YFS Blood PSMD9 0.04 0.03 bslmm 324 0.05 8.2e-15 -4.9 5.2 2.3e-07 -0.08 1.00 0.00 FALSE
40 The Cancer Genome Atlas Bladder Urothelial Carcinoma LRRC43 0.06 0.03 enet 6 0.03 8.7e-04 -4.4 -5.5 4.7e-08 0.10 0.13 0.23 TRUE
41 The Cancer Genome Atlas Breast Invasive Carcinoma DNAH10 0.11 0.03 blup 99 0.05 8.2e-11 5.3 6.4 1.2e-10 -0.05 0.03 0.97 FALSE
42 The Cancer Genome Atlas Breast Invasive Carcinoma VPS33A 0.01 0.02 lasso 2 0.02 2.7e-04 6.0 -6.1 1.3e-09 0.14 0.17 0.61 TRUE
43 The Cancer Genome Atlas Colon Adenocarcinoma MLXIP 0.06 0.04 lasso 7 0.02 2.7e-02 7.1 7.1 1.1e-12 -0.17 0.02 0.93 TRUE
44 The Cancer Genome Atlas Glioblastoma Multiforme CCDC92 0.07 0.02 blup 52 0.04 1.8e-02 5.2 5.8 7.0e-09 -0.05 0.03 0.67 FALSE
45 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DNAH10 0.07 0.03 lasso 3 0.05 7.4e-06 6.3 6.3 3.7e-10 -0.06 0.02 0.97 FALSE
46 The Cancer Genome Atlas Brain Lower Grade Glioma LRRC43 0.03 0.03 enet 8 0.02 1.5e-03 -4.2 -5.6 1.8e-08 0.15 0.10 0.07 FALSE
47 The Cancer Genome Atlas Brain Lower Grade Glioma VPS33A 0.03 0.05 lasso 1 0.05 4.4e-06 5.7 -5.7 9.9e-09 0.13 0.40 0.58 FALSE
48 The Cancer Genome Atlas Prostate Adenocarcinoma GPR81 0.07 0.02 blup 54 0.02 4.4e-03 5.7 5.4 5.5e-08 -0.13 0.04 0.20 FALSE
49 The Cancer Genome Atlas Prostate Adenocarcinoma LRRC43 0.04 0.00 blup 58 0.01 6.9e-02 6.6 -5.7 1.2e-08 0.12 0.02 0.20 FALSE
50 The Cancer Genome Atlas Prostate Adenocarcinoma VPS33A 0.04 0.05 lasso 1 0.04 3.0e-05 6.0 -6.0 1.7e-09 0.13 0.25 0.75 FALSE
51 The Cancer Genome Atlas Rectum Adenocarcinoma MLXIP 0.18 0.14 lasso 4 0.13 5.1e-04 6.6 7.0 3.3e-12 -0.16 0.02 0.90 TRUE
52 The Cancer Genome Atlas Stomach Adenocarcinoma MLXIP 0.06 0.02 blup 68 0.04 1.2e-03 7.2 8.3 1.3e-16 -0.23 0.02 0.86 TRUE
53 The Cancer Genome Atlas Thyroid Carcinoma DNAH10 0.04 0.03 lasso 5 0.02 4.6e-03 5.3 5.7 1.1e-08 -0.05 0.01 0.84 FALSE
54 The Cancer Genome Atlas Thyroid Carcinoma VPS33A 0.06 0.00 enet 8 0.03 9.6e-04 5.6 -6.8 1.1e-11 0.20 0.06 0.93 FALSE
55 The Cancer Genome Atlas Thyroid Carcinoma ZNF664 0.06 0.05 enet 9 0.05 2.8e-05 6.2 -6.5 6.3e-11 0.08 0.03 0.96 FALSE