[Hub]/) : Traits : Arm fat-free mass (left) :

chr12:121,453,962-125,155,900

Best TWAS P=7.36e-20 · Best GWAS P=1.02e-19 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC92 0.09 0.01 bslmm 438 0.03 3.1e-04 -3.9 5.4 5.3e-08 0.21 0.83 0.01 FALSE
2 CommonMind Brain Pre-frontal Cortex RILPL1 0.03 0.00 blup 379 0.02 1.5e-03 5.0 6.6 3.3e-11 0.08 0.08 0.72 FALSE
3 GTEx Adipose Subcutaneous ZCCHC8 0.04 0.00 lasso 7 0.00 1.4e-01 5.9 9.1 7.4e-20 0.01 0.12 0.38 TRUE
4 GTEx Adipose Subcutaneous CDK2AP1 0.20 0.18 lasso 11 0.19 1.0e-15 6.3 -6.6 3.5e-11 -0.05 0.03 0.97 FALSE
5 GTEx Adipose Subcutaneous RP11-282O18.3 0.15 0.14 lasso 7 0.15 2.0e-12 6.3 -6.6 5.2e-11 -0.05 0.03 0.97 FALSE
6 GTEx Adipose Visceral Omentum MPHOSPH9 0.07 0.02 lasso 4 0.00 3.5e-01 6.7 7.0 3.0e-12 0.04 0.14 0.08 FALSE
7 GTEx Adipose Visceral Omentum CDK2AP1 0.14 0.14 lasso 4 0.11 2.7e-06 6.7 -7.2 6.9e-13 -0.06 0.01 0.99 FALSE
8 GTEx Adipose Visceral Omentum RP11-282O18.3 0.14 0.11 enet 12 0.10 6.7e-06 6.7 -7.2 5.5e-13 -0.06 0.02 0.98 FALSE
9 GTEx Artery Aorta CDK2AP1 0.17 0.19 lasso 2 0.15 8.0e-09 6.3 -6.4 2.0e-10 -0.04 0.03 0.97 FALSE
10 GTEx Artery Aorta C12orf65 0.11 0.07 lasso 10 0.08 5.8e-05 5.7 -6.8 7.9e-12 -0.03 0.09 0.89 FALSE
11 GTEx Artery Aorta RP11-282O18.3 0.18 0.19 lasso 9 0.16 4.3e-09 6.3 -6.5 6.6e-11 -0.04 0.03 0.97 FALSE
12 GTEx Artery Tibial MPHOSPH9 0.05 0.03 lasso 3 0.03 2.2e-03 5.7 6.2 5.5e-10 0.02 0.59 0.03 FALSE
13 GTEx Artery Tibial SETD8 0.07 0.03 lasso 7 0.03 2.2e-03 6.3 6.8 9.4e-12 0.05 0.04 0.93 FALSE
14 GTEx Artery Tibial RP11-282O18.3 0.17 0.08 enet 26 0.10 2.4e-08 5.7 -5.2 2.4e-07 -0.05 0.04 0.96 FALSE
15 GTEx Brain Cerebellum TMEM120B 0.28 0.06 enet 18 0.04 2.6e-02 5.7 -6.7 1.8e-11 0.01 0.07 0.11 TRUE
16 GTEx Brain Hippocampus CLIP1 0.27 0.14 lasso 4 0.12 1.0e-03 -3.7 -5.3 9.4e-08 -0.06 0.07 0.27 FALSE
17 GTEx Breast Mammary Tissue CDK2AP1 0.08 0.06 lasso 3 0.07 1.2e-04 6.0 -6.3 2.3e-10 -0.04 0.04 0.94 FALSE
18 GTEx Breast Mammary Tissue RP11-282O18.3 0.10 0.06 lasso 6 0.08 5.4e-05 6.0 -6.1 1.0e-09 -0.04 0.05 0.94 FALSE
19 GTEx Breast Mammary Tissue (Female) CDK2AP1 0.08 0.03 lasso 3 0.02 6.4e-02 6.5 -6.2 4.5e-10 -0.04 0.05 0.61 FALSE
20 GTEx Breast Mammary Tissue (Female) RP11-282O18.3 0.09 0.07 enet 8 0.08 2.8e-03 5.9 -6.4 1.7e-10 -0.04 0.08 0.78 FALSE
21 GTEx Cells Transformed fibroblasts OGFOD2 0.10 0.07 lasso 7 0.07 3.1e-06 3.0 5.2 1.8e-07 0.03 0.99 0.00 FALSE
22 GTEx Cells Transformed fibroblasts CDK2AP1 0.31 0.32 lasso 8 0.35 8.5e-27 6.3 -6.3 2.5e-10 -0.03 0.05 0.95 FALSE
23 GTEx Cells Transformed fibroblasts C12orf65 0.07 0.05 lasso 4 0.04 5.8e-04 6.1 -6.5 8.4e-11 -0.02 0.11 0.82 FALSE
24 GTEx Cells Transformed fibroblasts SETD8 0.10 0.12 enet 9 0.09 1.4e-07 3.8 5.6 2.5e-08 0.08 0.05 0.95 FALSE
25 GTEx Cells Transformed fibroblasts RP11-282O18.3 0.25 0.29 enet 16 0.28 2.2e-21 6.3 -6.4 1.5e-10 -0.03 0.05 0.95 FALSE
26 GTEx Colon Sigmoid ABCB9 0.18 0.16 lasso 6 0.15 4.8e-06 6.4 5.8 5.0e-09 0.05 0.83 0.01 FALSE
27 GTEx Colon Transverse CDK2AP1 0.17 0.19 enet 7 0.22 1.4e-10 6.5 -6.8 1.4e-11 -0.05 0.01 0.99 FALSE
28 GTEx Colon Transverse ABCB9 0.08 0.07 enet 5 0.09 5.3e-05 6.3 5.3 9.7e-08 0.05 0.70 0.01 FALSE
29 GTEx Colon Transverse MLXIP 0.20 0.18 enet 23 0.14 5.8e-07 7.8 7.2 5.9e-13 0.09 0.05 0.95 FALSE
30 GTEx Colon Transverse RP11-282O18.3 0.18 0.19 enet 8 0.19 1.8e-09 6.5 -6.6 3.2e-11 -0.04 0.02 0.98 FALSE
31 GTEx Esophagus Gastroesophageal Junction CDK2AP1 0.14 0.06 lasso 8 0.06 4.7e-03 6.3 -7.0 1.9e-12 -0.07 0.04 0.70 FALSE
32 GTEx Esophagus Gastroesophageal Junction RP11-282O18.3 0.16 0.06 lasso 9 0.07 2.3e-03 6.3 -6.4 1.2e-10 -0.03 0.04 0.80 FALSE
33 GTEx Esophagus Mucosa CDK2AP1 0.30 0.36 lasso 5 0.38 1.9e-26 6.5 -6.5 1.1e-10 -0.04 0.02 0.98 FALSE
34 GTEx Esophagus Mucosa RP11-282O18.3 0.29 0.34 lasso 4 0.34 1.9e-23 6.3 -6.3 3.5e-10 -0.04 0.04 0.96 FALSE
35 GTEx Esophagus Muscularis MPHOSPH9 0.18 0.18 enet 17 0.18 4.8e-11 6.1 5.9 3.8e-09 0.03 0.99 0.01 FALSE
36 GTEx Esophagus Muscularis CDK2AP1 0.17 0.10 enet 18 0.11 4.6e-07 6.5 -7.1 1.6e-12 -0.05 0.02 0.98 FALSE
37 GTEx Esophagus Muscularis C12orf65 0.06 0.04 lasso 4 0.04 2.0e-03 6.4 -5.9 3.9e-09 -0.03 0.04 0.94 FALSE
38 GTEx Esophagus Muscularis ABCB9 0.10 0.08 lasso 6 0.05 3.8e-04 6.3 5.3 1.2e-07 0.04 0.78 0.01 FALSE
39 GTEx Esophagus Muscularis RP11-282O18.3 0.19 0.11 lasso 6 0.10 2.1e-06 6.5 -6.0 1.4e-09 -0.03 0.03 0.97 FALSE
40 GTEx Heart Left Ventricle MPHOSPH9 0.06 0.04 lasso 5 0.04 4.2e-03 6.1 6.9 4.6e-12 0.07 0.36 0.03 FALSE
41 GTEx Heart Left Ventricle ABCB9 0.10 0.14 lasso 5 0.10 4.2e-06 5.3 5.3 9.2e-08 0.04 0.90 0.01 FALSE
42 GTEx Lung CDK2AP1 0.08 0.03 lasso 4 0.00 2.0e-01 6.3 -7.0 3.3e-12 -0.05 0.04 0.93 FALSE
43 GTEx Lung ABCB9 0.04 0.02 lasso 3 0.02 8.0e-03 6.1 5.8 5.0e-09 0.03 0.38 0.08 FALSE
44 GTEx Lung RP11-282O18.3 0.06 0.02 lasso 7 0.00 6.1e-01 6.3 -6.7 2.6e-11 -0.05 0.04 0.91 FALSE
45 GTEx Muscle Skeletal RSRC2 0.06 0.03 enet 7 0.04 9.6e-05 -4.0 -6.8 1.3e-11 -0.02 0.06 0.88 FALSE
46 GTEx Nerve Tibial MPHOSPH9 0.07 0.04 lasso 4 0.01 7.0e-02 6.4 7.0 2.3e-12 0.06 0.40 0.04 FALSE
47 GTEx Nerve Tibial CDK2AP1 0.11 0.11 enet 25 0.09 4.4e-07 6.3 -6.7 1.9e-11 -0.05 0.05 0.95 FALSE
48 GTEx Nerve Tibial C12orf65 0.05 0.07 lasso 3 0.06 3.0e-05 5.7 -5.9 3.8e-09 -0.01 0.13 0.77 FALSE
49 GTEx Nerve Tibial ABCB9 0.06 0.04 lasso 3 0.05 3.5e-04 6.3 6.6 5.3e-11 0.04 0.82 0.01 FALSE
50 GTEx Nerve Tibial KNTC1 0.12 0.05 lasso 5 0.05 1.9e-04 -4.7 -5.4 7.7e-08 -0.01 0.36 0.35 FALSE
51 GTEx Nerve Tibial RP11-282O18.3 0.10 0.10 enet 28 0.08 1.9e-06 6.3 -6.6 3.8e-11 -0.06 0.05 0.95 FALSE
52 GTEx Pancreas CDK2AP1 0.24 0.27 lasso 3 0.26 3.1e-11 6.5 -6.5 6.1e-11 -0.04 0.02 0.98 FALSE
53 GTEx Pancreas ARL6IP4 0.07 0.07 lasso 2 0.07 9.6e-04 5.3 -5.9 4.0e-09 -0.04 0.27 0.10 FALSE
54 GTEx Pancreas SETD8 0.20 0.12 lasso 5 0.13 3.4e-06 6.4 -6.1 1.3e-09 -0.04 0.02 0.98 FALSE
55 GTEx Pancreas RP11-282O18.3 0.22 0.24 lasso 5 0.24 2.3e-10 6.3 -6.5 7.2e-11 -0.04 0.03 0.97 FALSE
56 GTEx Skin Not Sun Exposed Suprapubic CDK2AP1 0.17 0.12 lasso 10 0.12 3.4e-07 6.4 -6.6 5.3e-11 -0.04 0.05 0.95 FALSE
57 GTEx Skin Not Sun Exposed Suprapubic RP11-282O18.3 0.13 0.10 lasso 6 0.09 1.9e-05 6.0 -6.6 5.1e-11 -0.04 0.06 0.94 FALSE
58 GTEx Skin Sun Exposed Lower leg CDK2AP1 0.21 0.22 lasso 5 0.22 3.4e-18 6.3 -6.5 7.4e-11 -0.04 0.04 0.96 FALSE
59 GTEx Skin Sun Exposed Lower leg WDR66 0.19 0.10 lasso 5 0.08 5.5e-07 6.1 7.3 2.3e-13 0.00 0.98 0.01 TRUE
60 GTEx Skin Sun Exposed Lower leg RP11-282O18.3 0.17 0.20 lasso 6 0.20 2.2e-16 6.3 -6.3 2.3e-10 -0.03 0.04 0.96 FALSE
61 GTEx Small Intestine Terminal Ileum ABCB9 0.23 0.21 enet 12 0.22 1.0e-05 6.1 5.6 1.9e-08 0.06 0.29 0.06 FALSE
62 GTEx Stomach MPHOSPH9 0.17 0.08 lasso 5 0.10 1.2e-05 6.3 6.0 2.0e-09 0.04 0.82 0.03 FALSE
63 GTEx Testis MPHOSPH9 0.28 0.27 enet 23 0.32 1.3e-14 6.0 5.8 5.7e-09 0.03 1.00 0.00 FALSE
64 GTEx Testis CDK2AP1 0.20 0.14 lasso 5 0.13 2.0e-06 5.2 -5.4 7.7e-08 -0.04 0.24 0.74 FALSE
65 GTEx Testis ABCB9 0.14 0.05 lasso 3 0.06 8.0e-04 6.4 -7.9 2.3e-15 -0.08 0.20 0.22 FALSE
66 GTEx Testis RP11-282O18.3 0.18 0.09 lasso 9 0.12 7.8e-06 5.2 -5.5 5.0e-08 -0.02 0.19 0.48 FALSE
67 GTEx Testis RP11-380L11.3 0.14 0.05 enet 29 0.06 1.4e-03 -3.7 -6.0 2.2e-09 -0.33 0.14 0.21 TRUE
68 GTEx Thyroid MPHOSPH9 0.10 0.08 enet 20 0.09 2.0e-07 5.8 6.3 3.4e-10 0.06 0.99 0.01 FALSE
69 GTEx Thyroid PITPNM2 0.04 0.07 lasso 2 0.06 1.6e-05 6.5 6.4 1.3e-10 0.05 0.84 0.02 FALSE
70 GTEx Thyroid CDK2AP1 0.08 0.09 enet 7 0.10 8.2e-08 6.3 -6.6 4.8e-11 -0.04 0.02 0.98 FALSE
71 GTEx Thyroid TMEM120B 0.09 0.04 lasso 5 0.04 4.2e-04 6.3 -5.4 6.4e-08 0.02 0.32 0.05 TRUE
72 GTEx Thyroid RP11-282O18.3 0.06 0.06 enet 6 0.06 3.6e-05 6.3 -6.7 3.0e-11 -0.03 0.02 0.97 FALSE
73 METSIM Adipose ABCB9 0.04 0.03 enet 19 0.03 7.7e-05 -4.3 -5.4 5.6e-08 0.00 0.12 0.52 TRUE
74 METSIM Adipose CDK2AP1 0.11 0.14 enet 23 0.14 1.7e-20 6.1 -6.2 6.7e-10 -0.02 0.06 0.94 FALSE
75 METSIM Adipose CLIP1 0.03 0.01 bslmm 372 0.01 3.3e-03 -4.7 5.9 3.8e-09 0.03 0.40 0.36 FALSE
76 METSIM Adipose WDR66 0.04 0.00 blup 341 0.01 1.4e-02 6.3 6.6 4.7e-11 0.02 0.04 0.14 FALSE
77 YFS Blood MPHOSPH9 0.05 0.07 enet 31 0.07 3.7e-23 6.2 6.5 5.8e-11 0.03 0.99 0.01 FALSE
78 YFS Blood PSMD9 0.04 0.03 bslmm 324 0.05 8.2e-15 -3.7 5.3 9.0e-08 0.02 1.00 0.00 TRUE
79 YFS Blood SBNO1 0.03 0.03 lasso 6 0.03 1.2e-09 6.3 -5.8 7.3e-09 -0.04 0.06 0.94 FALSE
80 The Cancer Genome Atlas Bladder Urothelial Carcinoma ABCB9 0.05 0.04 enet 5 0.04 2.4e-04 6.1 6.3 2.7e-10 0.02 0.00 0.98 FALSE
81 The Cancer Genome Atlas Bladder Urothelial Carcinoma CDK2AP1 0.09 0.08 lasso 2 0.06 5.9e-06 6.3 -6.3 2.4e-10 -0.04 0.00 1.00 FALSE
82 The Cancer Genome Atlas Bladder Urothelial Carcinoma LRRC43 0.06 0.03 enet 6 0.03 8.7e-04 -4.5 -5.7 1.0e-08 -0.03 0.13 0.22 FALSE
83 The Cancer Genome Atlas Breast Invasive Carcinoma CDK2AP1 0.07 0.08 lasso 7 0.08 5.0e-16 6.3 -6.3 3.5e-10 -0.04 0.01 0.99 FALSE
84 The Cancer Genome Atlas Breast Invasive Carcinoma RILPL2 0.02 0.01 enet 8 0.01 2.6e-02 6.4 6.0 1.5e-09 0.03 0.00 0.98 FALSE
85 The Cancer Genome Atlas Breast Invasive Carcinoma VPS33A 0.01 0.02 lasso 2 0.02 2.7e-04 6.8 -6.9 6.6e-12 0.03 0.03 0.93 FALSE
86 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CDK2AP1 0.07 0.07 blup 34 0.05 1.1e-03 6.0 -6.4 1.4e-10 -0.03 0.01 0.90 FALSE
87 The Cancer Genome Atlas Colon Adenocarcinoma CDK2AP1 0.12 0.17 lasso 4 0.17 6.3e-10 6.3 -6.3 3.6e-10 -0.04 0.00 1.00 FALSE
88 The Cancer Genome Atlas Colon Adenocarcinoma MLXIP 0.06 0.04 lasso 7 0.02 2.7e-02 7.5 7.2 5.5e-13 0.05 0.02 0.94 TRUE
89 The Cancer Genome Atlas Colon Adenocarcinoma RILPL2 0.09 0.09 blup 43 0.08 3.1e-05 6.4 5.6 1.8e-08 0.04 0.01 0.99 FALSE
90 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CDK2AP1 0.14 0.15 lasso 2 0.14 7.8e-16 6.3 -6.2 4.6e-10 -0.04 0.00 1.00 FALSE
91 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CDK2AP1 0.11 0.13 lasso 5 0.14 5.9e-16 6.3 -6.2 5.9e-10 -0.03 0.00 1.00 FALSE
92 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CDK2AP1 0.12 0.10 lasso 2 0.11 6.3e-07 6.3 -6.2 6.6e-10 -0.04 0.00 1.00 FALSE
93 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PITPNM2 0.06 0.07 lasso 5 0.09 1.2e-05 6.0 -5.7 1.1e-08 -0.02 0.12 0.87 FALSE
94 The Cancer Genome Atlas Brain Lower Grade Glioma LRRC43 0.03 0.03 enet 8 0.02 1.5e-03 -4.3 -6.1 9.1e-10 -0.01 0.10 0.08 TRUE
95 The Cancer Genome Atlas Brain Lower Grade Glioma VPS33A 0.03 0.05 lasso 1 0.05 4.4e-06 6.7 -6.7 2.3e-11 0.02 0.28 0.71 FALSE
96 The Cancer Genome Atlas Liver Hepatocellular Carcinoma CDK2AP1 0.11 0.11 enet 5 0.11 1.2e-05 6.3 -6.3 2.3e-10 -0.04 0.00 0.99 FALSE
97 The Cancer Genome Atlas Lung Adenocarcinoma CDK2AP1 0.03 0.04 lasso 1 0.04 1.2e-05 6.3 -6.3 2.4e-10 -0.04 0.00 1.00 FALSE
98 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CDK2AP1 0.04 0.04 lasso 3 0.03 3.8e-04 6.3 -6.2 5.0e-10 -0.04 0.00 0.98 FALSE
99 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CDK2AP1 0.07 0.06 enet 7 0.06 7.0e-05 6.3 -6.8 1.0e-11 -0.03 0.00 0.98 FALSE
100 The Cancer Genome Atlas Pancreatic Adenocarcinoma CDK2AP1 0.12 0.14 blup 34 0.15 7.2e-07 5.3 -6.5 9.1e-11 -0.03 0.01 0.99 FALSE
101 The Cancer Genome Atlas Prostate Adenocarcinoma CDK2AP1 0.06 0.07 lasso 2 0.06 1.7e-06 6.3 -6.3 3.1e-10 -0.03 0.00 1.00 FALSE
102 The Cancer Genome Atlas Prostate Adenocarcinoma LRRC43 0.04 0.00 blup 58 0.01 6.9e-02 7.0 -7.3 2.7e-13 0.02 0.02 0.20 TRUE
103 The Cancer Genome Atlas Prostate Adenocarcinoma VPS33A 0.04 0.05 lasso 1 0.04 3.0e-05 6.8 -6.8 1.1e-11 0.03 0.14 0.85 FALSE
104 The Cancer Genome Atlas Rectum Adenocarcinoma MLXIP 0.18 0.14 lasso 4 0.13 5.1e-04 7.2 7.4 1.5e-13 0.05 0.02 0.88 TRUE
105 The Cancer Genome Atlas Stomach Adenocarcinoma CDK2AP1 0.09 0.10 lasso 2 0.10 1.8e-07 6.3 -6.2 4.9e-10 -0.04 0.00 1.00 FALSE
106 The Cancer Genome Atlas Stomach Adenocarcinoma MLXIP 0.06 0.02 blup 68 0.04 1.2e-03 7.7 7.2 8.1e-13 0.08 0.02 0.88 FALSE
107 The Cancer Genome Atlas Testicular Germ Cell Tumors CDK2AP1 0.13 0.10 blup 34 0.11 8.2e-05 5.2 -5.6 2.7e-08 -0.04 0.02 0.96 FALSE
108 The Cancer Genome Atlas Thyroid Carcinoma CDK2AP1 0.08 0.10 lasso 2 0.10 1.3e-09 6.3 -6.3 2.5e-10 -0.04 0.00 1.00 FALSE
109 The Cancer Genome Atlas Thyroid Carcinoma MPHOSPH9 0.27 0.09 lasso 4 0.09 9.8e-09 6.1 6.0 2.3e-09 0.01 0.09 0.91 FALSE
110 The Cancer Genome Atlas Thyroid Carcinoma PITPNM2 0.04 0.03 enet 5 0.05 8.1e-06 5.6 6.2 7.2e-10 0.08 0.03 0.96 FALSE
111 The Cancer Genome Atlas Thyroid Carcinoma SBNO1 0.03 0.01 blup 59 0.02 9.4e-03 6.0 -6.2 5.3e-10 -0.01 0.01 0.65 FALSE
112 The Cancer Genome Atlas Thyroid Carcinoma VPS33A 0.06 0.00 enet 8 0.03 9.6e-04 5.9 -7.1 1.5e-12 0.02 0.38 0.57 TRUE