[Hub]/) : Traits : Trunk fat-free mass :

chr17:27,200,734-30,884,028

Best TWAS P=1.86e-37 · Best GWAS P=3.18e-46 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NF1 0.06 0.01 blup 410 0.04 1.1e-05 8.2 7.4 1.0e-13 -0.20 0.95 0.00 FALSE
2 GTEx Adipose Visceral Omentum TEFM 0.12 0.02 lasso 14 0.05 1.0e-03 1.9 -6.7 2.0e-11 0.21 0.08 0.09 FALSE
3 GTEx Adipose Visceral Omentum SUZ12P 0.08 0.07 enet 14 0.07 1.2e-04 3.1 -5.4 6.2e-08 0.38 0.67 0.19 FALSE
4 GTEx Artery Aorta ABHD15 0.20 0.03 enet 36 0.06 2.9e-04 -6.1 -8.4 4.3e-17 0.08 0.03 0.54 TRUE
5 GTEx Artery Aorta TEFM 0.13 0.02 enet 34 0.03 5.8e-03 1.9 -8.3 1.4e-16 0.57 0.15 0.78 FALSE
6 GTEx Artery Aorta CRLF3 0.12 0.03 enet 33 0.06 3.8e-04 1.9 -8.9 6.9e-19 0.53 0.25 0.70 TRUE
7 GTEx Artery Tibial RP11-848P1.7 0.54 0.00 lasso 10 0.02 7.3e-03 -7.8 -12.8 1.9e-37 0.47 0.02 0.06 TRUE
8 GTEx Brain Caudate basal ganglia TEFM 0.27 0.19 enet 41 0.20 2.7e-06 1.9 -5.2 2.5e-07 0.28 0.66 0.06 FALSE
9 GTEx Brain Cerebellar Hemisphere TEFM 0.31 0.28 lasso 6 0.29 3.6e-08 3.1 -5.4 8.0e-08 0.30 0.50 0.28 FALSE
10 GTEx Brain Cerebellar Hemisphere CRLF3 0.38 0.35 enet 26 0.35 6.0e-10 3.1 -6.8 7.2e-12 0.32 0.97 0.01 FALSE
11 GTEx Brain Cerebellum CRLF3 0.52 0.12 lasso 27 0.20 1.3e-06 -12.0 -10.8 4.0e-27 0.56 0.09 0.74 FALSE
12 GTEx Breast Mammary Tissue CRLF3 0.10 0.10 lasso 3 0.05 9.6e-04 3.7 -6.3 3.0e-10 0.31 0.09 0.62 FALSE
13 GTEx Cells EBV-transformed lymphocytes EVI2A 0.13 0.03 lasso 4 0.01 1.5e-01 8.2 -8.4 4.9e-17 0.17 0.16 0.04 FALSE
14 GTEx Cells Transformed fibroblasts OMG 0.06 0.02 lasso 2 0.01 2.5e-02 8.1 8.1 5.9e-16 -0.22 0.14 0.07 FALSE
15 GTEx Cells Transformed fibroblasts TEFM 0.15 0.09 lasso 16 0.09 6.1e-07 1.9 -5.5 3.5e-08 0.45 0.96 0.04 FALSE
16 GTEx Colon Transverse CRLF3 0.16 0.07 lasso 6 0.05 1.5e-03 1.9 -6.4 1.8e-10 0.42 0.15 0.64 FALSE
17 GTEx Esophagus Mucosa ABHD15 0.21 0.13 lasso 1 0.10 1.7e-07 -6.1 -6.1 1.4e-09 0.00 0.94 0.04 FALSE
18 GTEx Esophagus Muscularis BLMH 0.15 0.02 lasso 8 0.01 1.0e-01 -3.9 6.4 1.9e-10 -0.13 0.04 0.46 TRUE
19 GTEx Esophagus Muscularis CRLF3 0.17 0.12 lasso 6 0.18 5.1e-11 3.1 -8.5 1.6e-17 0.46 0.94 0.05 FALSE
20 GTEx Heart Atrial Appendage ANKRD13B 0.14 0.09 enet 8 0.11 1.2e-05 -6.1 -5.7 9.2e-09 0.04 0.39 0.17 FALSE
21 GTEx Muscle Skeletal TP53I13 0.08 0.02 lasso 4 0.02 2.2e-03 -6.1 6.3 3.9e-10 -0.08 0.11 0.09 FALSE
22 GTEx Nerve Tibial TEFM 0.16 0.01 lasso 4 0.06 2.7e-05 1.9 -6.2 7.8e-10 0.43 0.26 0.59 FALSE
23 GTEx Nerve Tibial CRLF3 0.38 0.16 lasso 14 0.19 3.0e-13 3.3 -7.2 4.3e-13 0.38 1.00 0.00 FALSE
24 GTEx Nerve Tibial RP11-68I3.4 0.17 0.12 lasso 5 0.10 6.8e-08 -6.1 5.3 9.3e-08 0.02 0.97 0.02 FALSE
25 GTEx Nerve Tibial SUZ12P 0.25 0.34 enet 44 0.35 1.1e-25 3.3 -5.5 4.4e-08 0.29 1.00 0.00 FALSE
26 GTEx Ovary CRLF3 0.21 0.14 lasso 4 0.11 1.0e-03 3.1 -7.3 2.9e-13 0.40 0.06 0.58 FALSE
27 GTEx Pituitary SUZ12P 0.29 0.23 lasso 9 0.32 6.0e-09 3.1 -7.0 2.4e-12 0.40 0.86 0.07 FALSE
28 GTEx Prostate CRLF3 0.26 0.09 lasso 14 0.14 2.7e-04 3.7 -5.3 1.2e-07 0.32 0.16 0.46 FALSE
29 GTEx Spleen EVI2A 0.22 0.12 lasso 4 0.07 8.3e-03 7.8 -7.8 6.6e-15 0.17 0.11 0.05 FALSE
30 GTEx Spleen OMG 0.41 0.10 enet 26 0.08 4.5e-03 8.1 7.7 1.7e-14 -0.23 0.64 0.03 FALSE
31 GTEx Testis CRLF3 0.26 0.19 enet 23 0.17 3.8e-08 3.3 -6.5 6.1e-11 0.38 0.99 0.00 FALSE
32 GTEx Thyroid TP53I13 0.14 0.16 enet 7 0.14 6.0e-11 -6.1 5.6 2.6e-08 0.05 0.96 0.04 FALSE
33 GTEx Thyroid COPRS 0.17 0.00 enet 43 0.01 1.2e-01 1.3 -5.4 5.9e-08 0.13 0.04 0.18 FALSE
34 GTEx Thyroid CRLF3 0.10 0.04 enet 35 0.08 1.1e-06 3.3 -7.0 2.0e-12 0.38 0.91 0.05 FALSE
35 GTEx Whole Blood EVI2A 0.07 0.04 lasso 4 0.04 2.6e-04 7.7 -8.1 6.8e-16 0.14 0.89 0.00 FALSE
36 METSIM Adipose CTD-2349P21.5 0.02 0.00 bslmm 252 0.01 3.0e-03 -10.4 -8.4 2.9e-17 0.33 0.04 0.31 FALSE
37 METSIM Adipose NF1 0.04 0.00 blup 396 0.01 5.5e-03 8.3 8.4 5.4e-17 -0.30 0.80 0.02 FALSE
38 METSIM Adipose TEFM 0.08 0.06 blup 246 0.06 8.8e-10 -14.3 -8.9 4.0e-19 0.57 0.00 1.00 TRUE
39 METSIM Adipose TP53I13 0.05 0.02 enet 8 0.03 2.7e-05 -3.9 5.3 1.1e-07 -0.04 0.87 0.01 FALSE
40 YFS Blood EVI2A 0.03 0.05 lasso 4 0.04 1.0e-13 7.8 -7.8 6.3e-15 0.10 1.00 0.00 FALSE
41 YFS Blood EVI2B 0.01 0.00 blup 339 0.00 6.4e-02 0.1 7.9 3.3e-15 -0.26 0.07 0.02 FALSE
42 The Cancer Genome Atlas Bladder Urothelial Carcinoma EVI2A 0.03 0.03 blup 37 0.03 2.3e-03 7.8 -7.7 1.7e-14 0.10 0.06 0.42 FALSE
43 The Cancer Genome Atlas Bladder Urothelial Carcinoma OMG 0.02 0.02 blup 31 0.02 3.2e-03 7.7 -8.4 6.5e-17 0.15 0.03 0.76 FALSE
44 The Cancer Genome Atlas Breast Invasive Carcinoma ABHD15 0.04 0.03 lasso 2 0.02 1.4e-05 -6.1 -6.2 4.2e-10 -0.01 0.46 0.03 TRUE
45 The Cancer Genome Atlas Breast Invasive Carcinoma EVI2A 0.03 0.03 blup 38 0.03 6.9e-07 7.7 -8.0 1.6e-15 0.12 0.19 0.81 FALSE
46 The Cancer Genome Atlas Breast Invasive Carcinoma GOSR1 0.02 0.01 enet 4 0.01 1.7e-02 -7.9 7.9 3.3e-15 -0.27 0.01 0.83 FALSE
47 The Cancer Genome Atlas Breast Invasive Carcinoma OMG 0.03 0.04 lasso 1 0.04 1.1e-08 8.3 -8.3 8.7e-17 0.23 0.01 0.99 FALSE
48 The Cancer Genome Atlas Colon Adenocarcinoma LRRC37B2 0.09 0.00 enet 11 0.03 7.3e-03 3.2 -6.9 5.3e-12 0.47 0.01 0.26 FALSE
49 The Cancer Genome Atlas Esophageal Carcinoma OMG 0.09 0.09 blup 31 0.11 2.0e-04 8.4 -8.5 1.3e-17 0.18 0.02 0.92 FALSE
50 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EVI2A 0.04 0.00 blup 37 0.01 1.1e-02 7.7 -5.7 1.2e-08 0.00 0.02 0.12 FALSE
51 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma OMG 0.02 0.02 blup 31 0.03 6.9e-04 8.3 -8.4 3.4e-17 0.17 0.02 0.89 FALSE
52 The Cancer Genome Atlas Brain Lower Grade Glioma CRLF3 0.07 0.06 blup 37 0.08 2.8e-09 3.3 -5.7 1.4e-08 0.37 1.00 0.00 FALSE
53 The Cancer Genome Atlas Brain Lower Grade Glioma EVI2A 0.03 0.03 blup 38 0.04 3.0e-05 7.7 -8.4 4.2e-17 0.16 0.04 0.96 FALSE
54 The Cancer Genome Atlas Liver Hepatocellular Carcinoma NF1 0.04 0.03 blup 111 0.03 1.3e-02 8.4 8.5 2.6e-17 -0.19 0.05 0.68 FALSE
55 The Cancer Genome Atlas Lung Adenocarcinoma C17orf42 0.04 0.02 enet 5 0.04 5.4e-05 -1.4 -6.2 7.3e-10 0.46 0.17 0.46 FALSE
56 The Cancer Genome Atlas Lung Adenocarcinoma EVI2A 0.04 0.06 blup 38 0.06 3.0e-07 7.6 -8.3 1.2e-16 0.15 0.13 0.87 FALSE
57 The Cancer Genome Atlas Lung Adenocarcinoma OMG 0.05 0.03 lasso 5 0.04 3.6e-05 7.6 -6.9 7.1e-12 0.10 0.09 0.80 FALSE
58 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EVI2A 0.03 0.03 lasso 1 0.02 2.4e-03 7.5 -7.5 8.7e-14 0.10 0.05 0.22 FALSE
59 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma GOSR1 0.15 0.00 blup 56 0.04 1.1e-03 -3.0 7.1 1.6e-12 -0.35 0.04 0.18 FALSE
60 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma OMG 0.05 0.03 blup 32 0.03 5.6e-03 8.1 -7.9 2.0e-15 0.25 0.01 0.78 FALSE
61 The Cancer Genome Atlas Pancreatic Adenocarcinoma CRLF3 0.07 0.06 blup 40 0.06 2.0e-03 3.3 -5.6 2.3e-08 0.32 0.09 0.19 FALSE
62 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CRLF3 0.28 0.13 blup 40 0.11 3.1e-05 2.6 -5.9 3.0e-09 0.28 0.33 0.06 FALSE
63 The Cancer Genome Atlas Prostate Adenocarcinoma ABHD15 0.11 0.08 lasso 2 0.09 1.1e-09 -4.0 -5.1 2.9e-07 -0.03 0.99 0.01 FALSE
64 The Cancer Genome Atlas Prostate Adenocarcinoma ATAD5 0.14 0.08 enet 11 0.09 4.1e-10 1.9 5.8 7.1e-09 -0.41 0.99 0.01 FALSE
65 The Cancer Genome Atlas Prostate Adenocarcinoma EVI2A 0.08 0.12 lasso 3 0.12 1.3e-12 8.3 -8.2 2.5e-16 0.12 0.17 0.83 FALSE
66 The Cancer Genome Atlas Stomach Adenocarcinoma EVI2A 0.05 0.03 enet 7 0.04 4.8e-04 4.7 -7.1 1.7e-12 0.13 0.04 0.63 FALSE
67 The Cancer Genome Atlas Stomach Adenocarcinoma SUZ12P 0.05 0.05 blup 29 0.04 5.1e-04 3.7 -6.5 7.0e-11 0.32 0.16 0.16 TRUE
68 The Cancer Genome Atlas Thyroid Carcinoma OMG 0.02 0.01 blup 32 0.02 4.8e-03 8.1 -8.5 2.2e-17 0.18 0.02 0.87 FALSE