TWAS hub - KRTCAP3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1000	0.0530	9.0e-04	0.066	NA	0.055	NA	0.059	2.6e-04	NA	7.9e-04	NA	5.2e-04
2	GTEx	Adrenal Gland	0.1139	0.0471	1.2e-04	0.157	NA	0.061	NA	0.150	2.9e-06	NA	3.1e-03	NA	4.9e-06
3	GTEx	Brain Cortex	0.1890	0.0860	7.0e-04	0.096	NA	0.069	NA	0.119	1.3e-03	NA	6.0e-03	NA	3.7e-04
4	GTEx	Muscle Skeletal	0.0846	0.0321	1.3e-06	0.057	NA	0.038	NA	0.045	2.9e-06	NA	1.3e-04	NA	3.1e-05
5	GTEx	Skin Sun Exposed Lower leg	0.1000	0.0430	3.6e-05	0.023	NA	0.031	NA	0.029	4.7e-03	NA	1.2e-03	NA	1.8e-03
6	GTEx	Spleen	0.3840	0.1170	1.8e-04	0.014	NA	0.120	NA	0.065	1.4e-01	NA	5.4e-04	NA	9.2e-03
7	GTEx	Thyroid	0.1270	0.0570	5.0e-04	0.101	NA	0.052	NA	0.062	4.1e-08	NA	7.5e-05	NA	1.7e-05
8	GTEx	Whole Blood	0.1190	0.0480	2.6e-06	0.046	NA	0.054	NA	0.047	4.4e-05	NA	9.9e-06	NA	3.7e-05
9	METSIM	Adipose	0.0475	0.0220	6.2e-06	0.015	0.031	0.026	0.031	0.014	2.4e-03	1.6e-05	7.9e-05	1.8e-05	2.6e-03
10	ROSMAP	Brain Pre-frontal Cortex	0.0578	0.0235	9.4e-07	0.053	0.051	0.034	0.048	0.041	1.8e-07	3.1e-07	3.2e-05	6.9e-07	4.5e-06
11	YFS	Blood	0.1158	0.0271	0.0e+00	0.175	0.175	0.175	0.177	0.175	9.8e-55	5.0e-55	9.0e-55	1.0e-55	7.5e-55
12	TCGA	Breast Invasive Carcinoma	0.0133	0.0126	5.3e-03	0.004	0.002	0.000	NA	0.000	3.7e-02	8.7e-02	2.9e-01	NA	2.8e-01
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0221	0.0187	3.2e-03	0.008	0.009	0.004	NA	0.006	3.9e-02	2.8e-02	1.0e-01	NA	6.0e-02
14	TCGA	Brain Lower Grade Glioma	0.0377	0.0328	7.7e-03	0.006	0.015	0.011	NA	0.015	5.4e-02	7.5e-03	1.6e-02	NA	6.5e-03
15	TCGA	Pheochromocytoma and Paraganglioma	0.4210	0.1650	1.3e-03	0.015	0.051	0.104	NA	0.058	8.1e-02	4.4e-03	6.4e-05	NA	2.6e-03
16	TCGA	Thyroid Carcinoma	0.0420	0.0490	3.2e-03	0.038	0.023	0.032	NA	0.033	1.3e-04	2.4e-03	3.8e-04	NA	3.4e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Triglycerides	63.3	103.7	166.4	-12.5	-12.6	-11.7	-12.5	-2.9	-5.8	3.4	-12.9	-11.6	-11.9	-12.0	-10.6	-11.9	-4.1	-4.6	-10.9
Had menopause	25.6	32.0	44.2	5.7	6.7	6.0	6.5	4.7	3.2	2.4	6.0	5.7	6.0	6.6	6.5	6.4	5.3	4.1	6.5
Gout (self-reported)	25.3	34.6	55.1	-6.9	-7.2	-6.2	-7.4	-2.8	-4.9	-0.3	-7.1	-6.6	-7.0	-7.0	-6.1	-6.7	-3.8	-2.2	-5.9
Medication: Allopurinol	17.4	23.2	38.3	-5.4	-5.7	-5.1	-5.8	-2.5	-4.4	-0.7	-6.0	-5.8	-6.2	-5.6	-4.6	-5.2	-3.2	-1.7	-4.7
Fasting Glucose	17.0	20.4	38.3	6.2	5.5	4.7	5.5	1.5	3.9	-1.6	5.8	2.2	4.0	5.0	5.7	5.6	1.9	3.8	4.9
High cholesterol (Self-reported)	13.9	24.6	39.9	-5.8	-6.2	-5.9	-6.1	-1.2	-3.1	2.3	-6.3	-5.6	-5.2	-5.6	-5.4	-5.8	-1.7	-1.4	-5.9
Blood Platelet Count	10.5	121.8	190.4	-13.8	-13.1	-11.6	-13.2	-6.0	-8.4	0.5	-13.5	-11.1	-12.5	-13.1	-12.2	-12.4	-6.5	-6.2	-12.4
Alcohol intake frequency.	10.0	23.4	40.1	-6.3	-6.1	-5.3	-6.1	-1.6	-3.4	2.0	-6.0	-4.7	-5.2	-5.9	-5.2	-5.5	-1.7	-1.6	-5.5
Blood White Count	9.8	72.6	114.5	-10.6	-10.1	-9.2	-10.2	-3.9	-5.4	1.5	-9.9	-10.7	-10.0	-9.9	-9.4	-9.7	-4.3	-3.7	-9.4
Ever used hormone-replacement therapy (HRT)	9.6	12.3	18.0	3.4	3.9	3.8	3.8	3.3	2.6	2.2	3.6	4.2	3.9	4.0	3.6	3.9	3.7	1.5	3.5
Type 2 Diabetes (T2D) (2018)	8.7	16.4	26.1	5.0	4.8	4.8	4.8	1.8	3.0	-0.7	4.2	5.1	4.4	4.9	4.4	4.8	2.1	1.5	4.5
Medication: Atorvastatin	8.5	10.5	18.4	-4.0	-4.3	-3.7	-4.3	-1.1	-2.4	1.3	-3.9	-3.1	-2.9	-3.9	-3.7	-4.0	-1.3	-1.0	-3.6
Diabetes diagnosed by doctor	8.0	13.2	23.4	4.4	4.5	4.4	4.4	0.9	1.7	-1.1	4.2	4.8	3.9	4.3	3.8	4.4	1.6	0.5	4.0
Diabetes (self-reported)	7.8	12.0	21.6	4.2	4.4	4.3	4.3	0.4	1.1	-1.7	4.0	4.6	3.5	4.1	3.7	4.3	1.2	0.4	3.8
Hayfever, allergic rhinitis or eczema	7.7	16.8	25.2	-3.8	-4.3	-4.6	-4.2	-3.2	-3.8	-1.4	-4.3	-5.0	-4.7	-4.6	-4.4	-4.4	-3.5	-2.8	-4.8
Alcohol intake versus 10 years previously	6.7	10.0	14.2	-3.6	-3.7	-3.4	-3.7	-2.1	-3.7	-0.6	-3.5	-2.9	-3.4	-3.8	-3.2	-3.5	-2.3	-2.3	-3.4
Number of treatments/medications taken	6.5	11.7	17.6	-3.9	-3.9	-3.5	-4.0	-2.2	-3.0	-0.3	-4.0	-2.9	-3.7	-3.7	-4.0	-3.8	-2.5	-2.9	-4.2
Medication: Cholesterol lowering	6.5	10.0	20.9	-3.5	-4.0	-3.5	-4.0	-0.3	-2.7	1.8	-4.6	-3.4	-3.4	-3.5	-3.4	-3.7	-0.8	-0.5	-3.4
Diverticular disease/diverticulitis (self-reported)	6.4	7.6	9.7	-3.0	-2.8	-2.6	-2.8	-3.1	-2.3	-1.9	-2.5	-3.1	-2.9	-3.0	-2.9	-2.8	-2.9	-2.3	-2.9
Allergy or Eczema	6.1	16.0	22.8	-3.6	-4.4	-4.4	-4.3	-3.1	-3.8	-1.2	-4.2	-4.8	-4.4	-4.6	-4.3	-4.3	-3.4	-3.1	-4.6
Cardiovascular Disease	5.7	18.8	35.4	-4.3	-5.3	-4.8	-5.0	-2.4	-3.5	-0.5	-6.0	-4.0	-4.6	-4.5	-4.7	-4.7	-3.1	-3.4	-5.2
Pulse rate, automated reading	5.7	18.4	30.9	-5.4	-5.2	-5.2	-5.1	-1.8	-2.0	1.0	-5.6	-5.2	-5.0	-4.8	-4.3	-4.8	-1.7	-1.4	-4.9
Schizophrenia vs Biploar Disorder	5.6	7.4	12.5	3.3	3.2	2.8	3.3	1.0	1.8	-0.3	2.9	3.3	3.5	3.1	3.0	3.1	1.5	1.9	2.9
Medication: Metformin	5.5	7.7	15.8	3.3	3.3	3.2	3.2	1.3	1.5	-0.5	3.2	4.0	3.2	3.2	2.9	3.2	1.3	0.6	3.1
Eye problems/disorders: Cataract	5.5	6.3	11.6	-3.4	-3.1	-2.6	-3.1	-1.6	-1.6	0.1	-2.8	-2.5	-2.6	-2.9	-3.0	-3.0	-1.6	-1.5	-2.7
Medication for pain relief, constipation, heartburn	5.4	9.2	14.0	3.5	3.4	2.6	3.4	2.3	3.5	0.4	3.4	2.0	3.1	3.0	3.6	3.1	2.2	3.7	3.4
Cholesterol lowering medication	5.4	8.0	13.0	-3.6	-3.4	-3.5	-3.5	-1.1	-1.9	1.0	-3.2	-3.1	-3.1	-3.1	-3.0	-3.3	-1.0	-0.3	-3.5
Crohns Disease (2017)	5.3	11.7	17.9	-3.4	-4.2	-4.0	-4.1	-1.7	-3.2	-1.1	-4.0	-3.9	-3.6	-4.1	-3.4	-4.1	-2.9	-0.9	-3.5
Irritable Bowel Disease (IBD)	5.2	12.4	18.7	-3.7	-4.3	-4.0	-4.2	-2.2	-3.0	-1.2	-4.1	-3.7	-3.5	-4.0	-3.7	-4.2	-3.1	-1.7	-3.7
Number of self-reported non-cancer illnesses	5.2	9.1	15.4	-3.6	-3.3	-3.5	-3.3	-0.9	-3.6	0.1	-3.9	-3.2	-3.5	-3.0	-3.1	-3.3	-1.7	-1.4	-3.5
Vitamin and mineral supplements	5.1	6.9	14.1	2.8	2.6	2.3	2.8	2.5	2.5	1.2	2.8	1.2	2.4	2.6	3.0	2.6	2.6	3.8	3.1
Age when periods started (menarche)	5.0	12.0	25.0	2.9	3.0	3.5	2.8	5.0	3.4	4.4	2.8	3.1	3.3	3.1	3.0	3.0	4.6	2.7	3.5
Ulcerative Colitis	4.7	6.8	10.5	-2.7	-3.1	-3.0	-3.0	-2.0	-2.3	-1.1	-3.2	-2.4	-2.6	-2.6	-2.7	-2.9	-2.4	-2.0	-2.9
Lupus	4.4	6.7	10.0	-2.3	-2.8	-2.6	-2.8	-2.2	-3.2	-1.3	-3.0	-3.1	-3.0	-2.8	-2.6	-2.8	-2.4	-1.3	-2.4
Unable to work because of sickness or disability	4.2	5.5	9.6	2.4	2.3	2.1	2.2	2.3	2.5	2.2	2.4	3.1	3.1	2.4	2.0	2.3	2.6	0.6	1.8
Major Depression (MDD)	4.1	5.0	7.6	1.9	2.3	2.1	2.3	2.7	1.5	1.9	1.5	2.1	1.8	2.6	2.4	2.3	2.8	2.6	2.4
Pulse rate	4.1	6.9	11.5	-3.2	-3.0	-3.4	-3.1	-1.4	-1.5	0.1	-3.2	-3.4	-3.2	-2.9	-2.5	-2.9	-1.2	-0.2	-3.1
Medication: Paracetamol	4.1	6.9	13.2	-2.8	-3.1	-1.9	-2.9	-1.9	-2.1	-0.5	-3.6	-1.9	-3.0	-2.6	-3.1	-2.7	-2.1	-3.6	-2.5
High blood pressure (siblings)	4.1	6.0	10.0	-2.2	-2.7	-2.3	-2.4	-1.8	-2.7	-0.7	-3.0	-1.9	-2.5	-2.4	-2.7	-2.2	-1.9	-3.2	-3.2
Health satisfaction	4.1	5.3	9.1	-2.4	-2.6	-2.6	-2.7	-1.6	-1.9	-0.1	-3.0	-1.5	-2.2	-2.5	-2.7	-2.6	-1.6	-2.1	-2.9
Stomach or abdominal pain in last month	4.0	4.9	9.7	-2.6	-2.7	-2.8	-2.9	-0.8	-0.7	1.1	-2.4	-0.9	-1.4	-2.5	-3.0	-2.9	-1.0	-1.7	-3.1
Illnesses of siblings	3.9	5.4	9.3	2.1	2.4	2.4	2.3	2.0	3.0	1.1	2.3	1.9	2.2	2.3	2.5	2.2	2.1	2.6	3.0
Seen a psychiatrist for nerves, anxiety, tension or depression	3.9	5.1	8.2	1.7	2.2	2.0	2.2	2.9	1.9	2.3	1.7	2.6	2.5	2.6	2.3	2.2	2.9	1.7	2.2
Schizophrenia (2018)	3.8	7.9	13.7	2.6	2.9	2.8	2.9	2.3	2.1	1.2	2.0	3.7	3.2	3.1	3.1	2.7	2.5	3.2	3.5
Medication: Ibuprofen (e.g. Nurofen)	3.8	4.9	8.9	-2.4	-2.3	-1.5	-2.3	-1.9	-2.6	-1.5	-2.3	-1.5	-2.6	-2.1	-2.4	-1.8	-2.2	-3.0	-2.2
Arm fat-free mass (right)	3.6	18.6	35.9	4.8	5.2	5.2	5.0	1.4	4.0	-1.5	4.8	6.0	5.2	5.1	3.9	5.0	1.5	-1.0	4.4
Medication for cholesterol, blood pressure or diabetes	3.4	5.6	11.5	2.5	2.8	2.4	2.9	1.1	2.4	-0.1	3.4	2.4	2.5	2.6	2.5	2.6	1.4	1.5	2.4
Allergy	3.3	7.6	13.0	2.6	2.8	3.3	2.6	2.1	2.7	0.9	3.1	3.6	3.2	2.7	2.9	2.9	2.3	1.9	3.4
Trunk predicted mass	3.3	19.0	33.8	5.1	5.1	5.2	5.0	1.0	4.4	-1.9	4.9	5.8	5.3	5.1	4.0	5.0	1.2	-0.8	4.5
Bilateral oophorectomy (both ovaries removed)	3.2	3.7	5.9	-2.4	-2.1	-1.7	-2.2	-0.9	-1.6	-0.0	-2.4	-2.1	-2.2	-1.9	-2.3	-2.0	-1.2	-2.0	-2.2
Trunk fat-free mass	3.2	18.5	32.9	5.0	5.0	5.1	5.0	1.0	4.4	-1.9	4.8	5.7	5.3	5.1	3.9	4.9	1.2	-0.9	4.4
Headache pain in last month	3.2	5.4	8.8	-2.7	-3.0	-2.3	-2.8	-1.2	-2.0	0.5	-2.7	-2.5	-2.6	-2.8	-2.7	-2.6	-1.2	-1.3	-2.6
Arm predicted mass (right)	3.2	16.5	32.9	4.5	4.8	4.9	4.7	1.0	3.8	-1.7	4.5	5.7	5.0	4.8	3.6	4.6	1.1	-1.1	4.1
Primary Biliary Cirrhosis	3.1	4.4	9.6	-2.1	-2.3	-3.1	-2.5	-1.0	-2.4	-0.3	-2.8	-1.5	-2.2	-1.9	-2.0	-2.4	-1.4	-0.9	-2.6
Osteoporosis (self-reported)	3.1	3.8	6.5	-2.5	-2.3	-2.2	-2.4	-0.8	-2.3	0.1	-2.1	-1.7	-1.8	-2.2	-2.2	-2.3	-1.2	-1.1	-2.2
Fractured/broken bones in last 5 years	3.1	4.0	5.5	-2.2	-2.1	-2.2	-2.2	-1.8	-2.1	-1.6	-1.8	-1.0	-1.4	-2.2	-2.1	-2.1	-2.4	-2.1	-2.3
Arm predicted mass (left)	3.1	15.7	31.0	4.4	4.7	4.8	4.5	1.1	4.0	-1.5	4.4	5.6	4.8	4.7	3.5	4.5	1.2	-1.2	4.0
Systolic Blood Pressure	3.0	15.1	23.8	-4.3	-4.1	-3.6	-4.2	-2.9	-3.6	-1.3	-4.5	-4.1	-4.9	-3.8	-4.2	-3.7	-3.1	-4.1	-4.5
Diabetes (father)	3.0	3.8	7.5	2.0	2.3	2.4	2.3	0.4	1.6	-0.8	2.7	2.1	2.2	2.2	2.0	2.4	0.9	0.2	2.0
Medication for cholesterol	3.0	4.6	6.8	2.4	2.4	1.7	2.4	1.6	2.3	0.6	2.6	1.5	2.6	2.2	2.4	2.0	1.6	2.5	2.4
Arm fat-free mass (left)	3.0	15.3	29.3	4.4	4.7	4.7	4.5	1.1	4.0	-1.5	4.3	5.4	4.7	4.6	3.5	4.5	1.2	-1.1	3.9
Schizophrenia (2014)	2.9	6.4	12.1	2.3	2.7	2.8	2.6	2.0	1.8	0.9	1.8	3.5	2.6	2.7	2.8	2.6	2.3	2.7	3.2
Alcohol usually taken with meals	2.9	4.7	6.7	-2.3	-2.0	-2.0	-1.9	-2.2	-2.2	-1.9	-2.3	-2.2	-2.6	-2.2	-2.0	-1.9	-2.4	-2.2	-2.3
Standing height	2.9	28.5	47.9	6.4	6.1	6.3	6.1	2.9	4.3	0.1	5.5	6.9	6.4	6.3	5.6	6.2	3.2	1.1	5.8
Ever had stillbirth, spontaneous miscarriage or termination	2.9	3.1	5.9	-2.3	-1.9	-1.7	-2.1	-1.1	-0.7	0.1	-1.9	-1.5	-1.6	-1.8	-2.2	-1.8	-1.1	-2.4	-2.2
Whole body water mass	2.9	16.5	32.6	4.7	4.7	4.8	4.7	0.9	4.0	-2.1	4.4	5.7	5.0	4.8	3.7	4.6	0.9	-1.1	4.1
Medication: Simvastatin	2.8	4.2	8.1	-2.6	-2.4	-2.4	-2.5	0.2	-1.4	2.0	-2.8	-1.9	-2.2	-1.9	-2.2	-2.2	0.1	-0.4	-2.6
Comparative body size at age 10	2.8	7.7	12.9	-3.4	-3.2	-2.6	-3.2	-1.7	-2.3	-0.9	-2.8	-2.6	-3.3	-3.6	-3.1	-3.1	-2.4	-2.1	-2.9
Whole body fat-free mass	2.8	16.2	31.7	4.7	4.7	4.8	4.6	0.8	3.9	-2.2	4.4	5.6	4.9	4.8	3.7	4.6	0.8	-1.1	4.1
Sitting height	2.7	19.1	28.5	5.3	5.2	5.2	5.3	1.7	4.1	-0.6	4.8	5.0	5.0	5.1	4.5	5.2	2.2	1.0	4.7
Mouth/teeth dental problems: Bleeding gums	2.7	3.5	8.5	-1.9	-2.4	-1.7	-2.3	-0.2	-0.7	0.6	-2.9	-1.8	-2.3	-1.8	-2.1	-2.0	-0.9	-1.9	-1.9
Eye problems/disorders: None of the above	2.7	3.1	6.1	2.5	2.0	2.1	2.2	1.0	0.5	-1.1	1.8	1.6	1.5	2.0	2.3	2.2	0.5	0.8	2.2
Overall health rating	2.7	5.7	11.6	-2.5	-3.1	-3.0	-3.0	-0.5	-0.7	1.1	-3.4	-1.4	-1.7	-2.3	-3.1	-3.0	-1.1	-2.0	-3.2
Taking other prescription medications	2.6	4.0	8.0	-2.3	-2.0	-2.6	-2.2	-1.3	-2.8	-0.3	-2.2	-2.0	-2.1	-1.9	-2.0	-2.3	-1.4	-0.4	-2.3
High blood pressure (mother)	2.6	3.7	6.2	-2.1	-2.5	-1.4	-2.5	-1.0	-1.2	-0.3	-2.2	-1.8	-1.8	-2.3	-2.4	-2.0	-1.5	-2.2	-2.0
Medication: Gliclazide	2.6	2.9	4.9	2.1	2.2	1.6	2.0	0.4	1.1	-1.0	2.1	2.2	1.9	2.0	1.9	1.8	0.4	1.2	1.9
Bipolar Disorder (2011)	2.5	2.5	5.0	-1.9	-1.9	-2.1	-2.0	-0.8	-0.6	-0.1	-2.2	-1.1	-1.6	-1.8	-1.6	-2.1	-0.9	0.1	-1.6
Height	2.5	48.1	79.7	8.2	8.3	8.2	8.1	2.7	4.9	-1.1	7.6	8.9	8.3	8.1	7.3	8.2	3.6	1.9	7.5
Medication: Paracetamol	2.5	3.9	9.3	-2.1	-2.4	-1.3	-2.3	-1.0	-1.8	0.1	-2.7	-1.2	-2.1	-1.9	-2.4	-2.1	-1.3	-3.0	-1.8
Average weekly beer plus cider intake	2.5	3.6	7.2	1.6	1.5	1.2	1.6	2.7	2.1	2.0	1.4	2.3	2.5	2.0	1.8	1.5	2.2	1.9	1.6
Ulcerative Colitis (UC)	2.4	4.5	6.9	-2.5	-2.6	-2.2	-2.5	-1.5	-1.6	-0.8	-2.6	-2.0	-2.1	-2.2	-2.3	-2.5	-1.9	-1.6	-2.1
Multivitamins +/- minerals	2.4	3.0	5.4	-1.9	-2.0	-1.7	-2.1	-1.3	-1.0	0.1	-1.8	-0.7	-1.4	-2.0	-2.3	-2.0	-1.3	-2.0	-2.3
Number of children fathered	2.4	2.8	7.2	0.8	1.2	1.4	1.1	2.5	1.7	2.7	1.2	1.8	2.0	1.6	1.1	1.2	2.4	0.6	1.5
Medication: Ibuprofen	2.4	2.8	7.2	-1.7	-1.8	-0.9	-1.8	-1.3	-2.1	-0.8	-1.8	-0.9	-1.9	-1.6	-1.9	-1.3	-1.5	-2.7	-1.7
Hypertension (Self-reported)	2.4	6.6	12.0	-2.2	-2.8	-2.7	-2.7	-2.1	-2.9	-1.1	-3.5	-1.8	-2.6	-2.3	-2.7	-2.5	-2.3	-2.9	-3.1
Basal metabolic rate	2.4	13.5	28.7	4.2	4.2	4.3	4.2	0.7	3.6	-2.1	3.9	5.4	4.4	4.3	3.3	4.2	0.6	-1.3	3.6
Systolic blood pressure, automated reading	2.3	6.7	10.5	-3.2	-2.5	-2.5	-2.6	-2.1	-2.7	-0.8	-2.7	-2.8	-3.2	-2.3	-2.8	-2.4	-1.9	-2.6	-3.2
Pulse wave reflection index	2.3	2.8	4.6	1.4	1.4	2.1	1.6	2.1	1.9	1.4	1.6	2.1	2.0	1.6	1.2	1.5	1.6	0.1	1.9
Qualifications: O levels/GCSEs or equivalent	2.3	3.7	8.9	-1.3	-1.5	-1.7	-1.5	-2.5	-1.9	-2.4	-0.8	-3.0	-2.1	-2.1	-1.7	-1.7	-2.6	-1.0	-1.8
High blood pressure	2.2	6.2	12.7	-2.3	-2.8	-2.8	-2.7	-1.9	-2.5	-0.8	-3.6	-1.8	-2.5	-2.2	-2.7	-2.5	-2.1	-2.6	-3.1
Illnesses of father: High blood pressure	2.2	2.8	6.6	-1.3	-1.5	-1.2	-1.5	-2.1	-1.9	-1.4	-1.7	-1.3	-1.5	-1.6	-1.6	-1.3	-1.8	-2.6	-1.6
Townsend deprivation index at recruitment	2.1	2.9	5.1	1.7	1.4	1.5	1.4	2.3	1.8	1.6	1.4	1.4	1.8	1.6	1.6	1.5	2.0	2.0	1.8
Comparative height size at age 10	2.1	11.8	25.9	4.6	3.9	3.7	4.0	1.2	3.2	-0.9	3.6	5.1	4.4	3.9	3.3	3.9	1.1	-0.4	3.2
Family relationship satisfaction	2.1	2.6	4.7	1.9	2.0	2.1	1.9	1.0	0.9	0.2	1.8	2.2	1.8	1.8	1.6	1.9	1.1	0.0	1.8
Ovarian Cancer	2.0	2.7	4.3	-2.1	-2.1	-2.0	-2.0	-0.3	-0.6	0.2	-1.5	-1.7	-1.6	-1.9	-2.0	-2.0	-1.2	-1.2	-2.0
Leg fat-free mass (left)	2.0	10.8	24.2	3.8	3.7	3.8	3.8	0.5	3.0	-2.3	3.4	4.9	4.0	3.8	3.0	3.7	0.3	-1.2	3.3
Relative age voice broke	2.0	3.0	5.1	-2.1	-2.3	-2.0	-2.2	-0.5	-2.1	0.1	-1.8	-1.8	-1.5	-2.2	-1.8	-2.2	-1.1	-0.4	-1.5
Leg predicted mass (left)	2.0	10.6	24.0	3.8	3.7	3.7	3.7	0.5	2.9	-2.3	3.3	4.9	4.0	3.8	3.0	3.6	0.2	-1.2	3.3
Qualifications: nursing, teaching	2.0	3.2	7.8	-2.0	-1.3	-1.3	-1.4	-2.5	-1.7	-2.8	-1.4	-1.8	-2.1	-1.7	-1.3	-1.4	-2.5	-0.8	-1.3
Vascular/heart problems diagnosed by doctor	2.0	5.5	12.7	2.2	2.7	2.6	2.7	1.2	2.6	0.1	3.6	1.5	2.3	2.1	2.6	2.6	1.6	2.2	2.8
Pain experienced in last month	2.0	3.4	7.8	1.8	2.2	1.8	2.1	1.0	2.0	0.3	2.3	0.5	1.3	1.6	2.2	2.0	1.5	2.8	2.2
Crohns Disease (2012)	1.9	3.0	4.5	-1.7	-2.1	-1.9	-2.0	-1.0	-1.6	-0.8	-1.9	-1.7	-1.7	-2.1	-1.8	-1.9	-1.6	-1.5	-1.9
Worrier / anxious feelings	1.9	3.5	6.4	-1.9	-2.2	-1.9	-2.2	-1.1	-1.7	-0.3	-1.8	-2.5	-1.6	-2.1	-2.3	-2.3	-1.5	-1.4	-1.9
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	4.8	-1.4	-1.7	-1.4	-1.8	-0.8	-0.8	-0.1	-2.2	-1.8	-1.6	-1.7	-1.8	-1.6	-1.0	-1.5	-1.8
Leg predicted mass (right)	1.9	9.9	23.0	3.7	3.5	3.6	3.5	0.4	2.9	-2.3	3.2	4.8	4.0	3.6	2.8	3.5	0.1	-1.4	3.1
Heart disease (mother)	1.8	2.1	3.4	-1.8	-1.6	-1.4	-1.7	-1.3	-0.8	-0.4	-1.8	-1.7	-1.7	-1.6	-1.6	-1.6	-1.1	-0.7	-1.5
Leg fat-free mass (right)	1.8	9.9	23.0	3.7	3.4	3.7	3.5	0.4	2.9	-2.3	3.2	4.8	3.9	3.6	2.7	3.5	0.1	-1.5	3.1
Hand grip strength (left)	1.7	4.5	7.3	2.7	2.4	2.0	2.4	1.3	1.8	0.6	2.4	2.1	2.4	2.5	2.4	2.4	1.6	1.6	2.1
Hair/balding pattern: Pattern 3	1.7	2.6	3.6	1.7	1.8	1.9	1.9	1.2	1.4	0.5	1.7	1.6	1.7	1.7	1.7	1.9	1.4	1.1	1.6
Birth weight of first child	1.7	3.1	5.7	2.0	1.8	2.2	1.9	0.1	2.2	-1.0	2.4	1.7	2.2	1.3	1.8	1.8	0.3	0.9	2.3
Medication: Ventolin 100micrograms inhaler	1.7	2.2	3.9	-1.9	-1.5	-1.9	-1.4	-0.9	-1.5	-1.0	-1.7	-2.0	-1.6	-1.3	-1.1	-1.8	-1.5	0.1	-1.1
Hand grip strength (right)	1.6	4.2	6.2	2.4	2.3	2.5	2.4	1.2	2.0	0.1	2.4	2.0	2.3	2.3	2.3	2.4	1.4	0.8	2.3
Pain all over the body in last month	1.6	1.8	3.7	-1.8	-1.3	-1.3	-1.4	-0.4	-1.5	-0.4	-1.9	-0.8	-1.5	-1.0	-1.4	-1.3	-1.0	-1.6	-1.4
Supplements: Vitamin C	1.6	1.9	7.6	-0.9	-0.6	-0.6	-0.7	-1.9	-2.3	-1.9	-1.1	-0.0	-1.0	-0.6	-0.9	-0.5	-1.8	-2.8	-1.1
Number of operations (self-reported)	1.6	2.4	7.5	-2.1	-1.4	-0.6	-1.3	-0.5	-2.4	0.1	-2.0	-1.5	-2.0	-0.9	-1.5	-0.9	-0.5	-2.7	-1.4
Weight	1.5	7.6	22.0	3.0	3.2	3.0	3.2	0.8	2.6	-1.5	2.4	4.7	3.2	3.3	2.5	3.1	0.5	-1.2	2.6
Illnesses of mother	1.5	1.8	3.6	1.6	1.6	1.1	1.8	0.4	0.3	-0.7	1.8	1.0	1.1	1.6	1.9	1.5	0.5	1.4	1.7
Ever had bowel cancer screening	1.5	1.8	4.0	-1.4	-1.4	-1.1	-1.3	-1.2	-2.0	-1.3	-1.7	-1.1	-1.6	-1.2	-1.0	-1.2	-1.4	-0.9	-0.9
Commuting to job workplace: Public transport	1.5	1.7	4.8	1.3	1.1	1.0	1.3	1.5	2.2	1.0	1.6	0.0	1.0	1.1	1.2	1.2	1.4	1.8	1.2
Hair Pigment	1.4	40.8	65.4	-7.1	-8.1	-7.4	-8.0	-3.3	-4.5	1.5	-6.5	-6.3	-5.6	-7.1	-7.8	-7.8	-3.8	-4.5	-7.8
Serious illness, injury or assault to yourself	1.4	1.7	2.8	-1.2	-1.6	-1.4	-1.7	-0.3	-0.9	-0.1	-1.5	-1.2	-1.1	-1.4	-1.7	-1.6	-1.1	-1.5	-1.6
Illnesses of father: Heart disease	1.4	2.0	4.1	-1.9	-1.4	-1.6	-1.4	-0.2	-1.3	1.1	-2.0	-1.6	-1.8	-1.4	-1.4	-1.5	-0.0	-0.4	-1.7
Ever taken oral contraceptive pill	1.4	1.6	8.6	-0.1	-0.5	-0.6	-0.7	-1.9	-1.3	-2.9	-0.7	-0.9	-1.1	-0.8	-0.6	-0.6	-2.2	-1.1	-0.5
Hearing aid user	1.4	1.6	4.3	-0.7	-1.4	-1.9	-1.4	-0.4	-1.0	0.4	-1.5	-2.1	-1.1	-1.3	-1.2	-1.6	-0.5	0.8	-1.4
Reaction Time	1.3	2.5	4.2	-1.3	-1.6	-2.0	-1.7	-1.6	-1.9	-1.9	-1.1	-1.8	-1.3	-1.7	-1.2	-1.7	-2.1	-0.0	-1.2
Neuroticism	1.3	3.0	5.8	-2.2	-2.3	-1.8	-2.4	-0.5	-0.2	1.2	-1.9	-1.5	-1.2	-2.0	-2.4	-2.2	-0.6	-0.9	-2.1
Angina	1.3	1.7	3.7	-1.1	-1.6	-1.4	-1.5	1.5	-1.1	1.9	-1.9	-0.8	-0.6	-1.0	-1.1	-1.7	0.3	1.2	-0.8
Mood swings	1.3	2.3	4.0	-1.9	-2.0	-1.5	-2.0	-0.4	-1.0	1.2	-1.8	-1.1	-1.0	-1.5	-2.0	-1.9	-0.4	-1.3	-1.8
Bipolar Disorder (2018)	1.2	1.9	4.0	-1.9	-1.6	-1.5	-1.7	-0.5	-0.7	-0.0	-2.0	-1.2	-1.9	-1.4	-1.4	-1.8	-0.7	0.5	-1.1
Waist Hip Ratio (WHR)	1.2	5.3	13.7	1.3	2.0	1.2	1.9	3.5	1.8	3.7	1.6	2.2	2.7	2.5	1.9	1.9	3.6	1.5	1.3
Hearing difficulty/problems with background noise	1.2	1.9	3.9	-1.1	-0.8	-1.6	-0.8	-1.5	-2.0	-1.8	-1.6	-0.7	-1.6	-0.7	-0.9	-0.9	-1.6	-1.6	-1.6
Medication: Amlodipine	1.2	1.6	6.7	-0.2	-0.9	-0.3	-0.8	-2.1	-1.6	-1.9	-1.0	0.4	-0.5	-0.8	-1.0	-0.6	-1.8	-2.6	-0.8
Number of full brothers	1.2	1.5	2.7	1.4	1.4	1.6	1.4	0.8	1.1	0.1	1.2	1.4	1.0	1.3	1.3	1.6	1.0	0.2	1.2
Medication: Blood pressure	1.2	2.1	3.7	-1.2	-1.5	-1.5	-1.6	-1.4	-1.5	-0.7	-1.9	-0.9	-1.1	-1.4	-1.6	-1.4	-1.4	-1.8	-1.6
Miserableness	1.2	2.1	3.8	-1.7	-1.9	-1.4	-1.8	0.1	-0.3	1.3	-1.7	-1.9	-1.7	-1.5	-1.6	-1.6	-0.0	-0.3	-1.6
Age at First Birth	1.1	1.5	4.2	-0.7	-0.6	-0.8	-0.8	-1.8	-0.8	-1.5	-0.9	-2.0	-2.1	-1.3	-0.8	-0.9	-1.6	-1.0	-0.7
Relative age of first facial hair	1.1	2.2	4.4	-2.1	-1.8	-1.8	-1.8	1.0	-1.1	1.8	-1.6	-1.1	-1.3	-1.7	-1.2	-1.8	0.4	1.0	-1.3
Number of live births	1.1	1.6	2.4	-0.8	-1.2	-1.4	-1.3	-1.2	-1.3	-1.1	-1.2	-1.6	-1.3	-1.1	-1.2	-1.1	-1.3	-1.3	-1.5
Glaucoma (self-reported)	1.1	1.4	4.8	0.4	0.5	0.7	0.5	1.7	1.9	2.2	0.7	0.7	1.3	0.6	0.7	0.6	1.7	1.2	0.8
Chronic bronchitis/emphysema (mother)	1.1	1.3	3.9	-1.1	-1.1	-0.8	-1.3	-0.9	-1.2	-0.2	-1.4	-0.4	-1.0	-1.2	-1.5	-1.1	-0.9	-2.0	-1.2
Angina (self-reported)	1.1	1.5	4.1	-1.0	-1.4	-1.3	-1.3	1.6	-0.9	2.0	-1.8	-0.6	-0.4	-0.9	-0.9	-1.5	0.6	1.4	-0.6
Medication: Aspirin	1.1	1.5	3.6	-1.0	-1.3	-1.3	-1.4	-0.9	-1.9	0.3	-1.1	-0.7	-0.8	-1.5	-1.5	-1.4	-0.6	-0.9	-1.6
Mother’s age at death	1.1	1.3	2.5	1.3	1.5	1.0	1.4	0.5	-0.3	-1.0	1.1	1.1	0.8	1.4	1.6	1.4	0.3	1.5	1.2
Tinnitus: Yes, now most or all of the time	1.1	1.3	4.7	-0.9	-1.1	-1.0	-1.1	-0.7	-0.4	-1.1	-1.3	-2.2	-1.8	-1.2	-0.9	-1.0	-1.2	-0.2	-0.8
Body Mass Index (BMI) (2010)	1.0	1.4	3.9	1.6	1.3	1.7	1.3	0.5	0.9	-0.5	0.7	2.0	1.2	1.1	1.1	1.4	0.4	-0.2	1.3
Tanning	1.0	12.2	21.3	3.5	4.4	4.3	4.4	0.4	1.2	-2.4	4.3	4.6	3.8	3.9	3.8	4.1	0.6	0.2	4.2
Waist circumference	1.0	3.7	13.6	1.8	2.2	1.8	2.0	1.4	2.1	0.1	1.6	3.7	2.4	2.3	1.6	2.0	1.0	-1.1	1.3
Heart attack	1.0	1.3	5.5	-0.7	-1.5	-0.6	-1.6	0.1	-2.3	-0.1	-1.6	-0.2	-0.7	-1.1	-1.3	-1.5	-1.0	-0.6	-0.4
Mouth/teeth dental problems: Dentures	1.0	1.8	3.8	1.2	1.3	1.9	1.0	1.0	1.7	1.4	1.8	1.1	1.4	1.1	0.7	1.3	1.6	-0.0	1.4
Breastfed as a baby	1.0	1.2	2.7	0.9	1.6	1.6	1.5	-0.4	0.1	-1.3	1.3	1.1	0.5	1.0	1.3	1.5	-0.1	-0.2	1.3
Hair/balding pattern: Pattern 4	1.0	2.5	5.1	1.9	1.9	1.8	1.9	0.8	-0.1	-0.8	0.9	1.9	1.4	2.3	2.0	1.9	0.6	0.7	2.1
Age at first live birth	1.0	1.7	4.0	-1.7	-1.1	-1.0	-1.1	-1.6	-1.3	-1.3	-0.8	-2.0	-1.5	-1.6	-1.1	-1.3	-1.6	-0.5	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.9	-0.9	-1.3	-1.7	-1.3	-0.7	-1.2	0.2	-0.8	-1.3	-0.7	-1.1	-1.2	-1.4	-0.6	0.3	-1.4
Chest pain or discomfort	1.0	1.5	2.7	-1.5	-1.7	-1.6	-1.5	-0.1	0.6	0.7	-1.5	-1.1	-1.2	-1.3	-1.4	-1.5	-0.3	-0.2	-1.6
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.7	1.2	1.0	1.1	1.0	1.4	1.6	1.0	1.1	0.4	1.0	0.8	0.9	1.0	1.2	0.9	1.0
Medication: Blood pressure	1.0	2.0	3.3	-1.3	-1.6	-1.3	-1.5	-1.1	-1.8	-0.4	-1.8	-0.6	-1.4	-1.2	-1.6	-1.4	-1.1	-1.8	-1.8
Heart attack/myocardial infarction (self-reported)	1.0	1.3	5.4	-0.7	-1.5	-0.6	-1.6	0.2	-2.3	-0.1	-1.7	-0.1	-0.7	-1.0	-1.2	-1.5	-1.0	-0.4	-0.3
Bipolar Disorder or Schizophrenia	0.9	2.3	7.9	0.9	1.3	1.2	1.2	1.5	1.2	0.9	0.3	2.1	1.3	1.5	1.5	1.0	1.6	2.8	2.0
HDL Cholesterol	0.9	1.5	6.8	0.9	1.3	1.6	1.3	-0.1	0.7	-0.1	1.3	2.6	1.8	1.0	0.8	1.2	0.4	-0.7	1.0
Neuroticism (2016)	0.9	1.2	5.3	0.5	0.7	1.3	0.6	1.3	1.3	2.3	1.1	1.0	1.2	0.7	0.3	0.7	1.7	-0.4	0.6
Frequency of depressed mood in last 2 weeks	0.9	1.3	2.5	-1.0	-1.5	-1.4	-1.6	-0.0	-0.4	0.7	-1.3	-1.2	-1.0	-1.3	-1.4	-1.4	-0.3	-0.4	-1.5
Hearing difficulty/problems: Yes	0.9	1.4	3.9	-1.4	-1.2	-1.8	-1.1	-0.2	-1.1	0.1	-2.0	-1.4	-1.5	-0.9	-0.9	-1.2	-0.6	-0.6	-1.2
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	2.9	-1.7	-1.0	-1.6	-1.1	-0.1	-1.1	1.0	-1.3	-1.1	-1.3	-0.9	-0.9	-1.1	0.1	0.0	-1.4
Diabetes (mother)	0.9	1.2	3.8	1.4	1.3	0.7	1.3	0.1	0.1	-0.4	1.3	1.9	1.7	1.2	1.0	1.0	0.2	0.4	0.8
Medication: Ramipril	0.9	1.1	3.8	-0.4	-0.5	-0.3	-0.8	-1.2	-1.9	-1.5	-1.1	-0.7	-1.3	-1.0	-0.7	-0.7	-1.5	-1.4	-0.3
Neuroticism score	0.9	1.8	3.3	-1.4	-1.7	-1.5	-1.7	0.3	0.7	1.8	-1.2	-1.4	-0.6	-1.4	-1.8	-1.7	0.1	-0.2	-1.8
Qualifications: A levels/AS levels or equivalent	0.9	2.1	8.2	-0.8	-1.0	-1.7	-1.0	-1.8	-1.2	-1.6	-0.5	-2.9	-1.6	-1.4	-0.9	-1.4	-1.8	0.6	-1.1
Medication: Aspirin	0.9	1.1	2.9	-0.8	-1.2	-1.1	-1.3	-0.6	-1.7	0.6	-1.0	-0.4	-0.6	-1.3	-1.4	-1.2	-0.4	-0.9	-1.4
Loneliness, isolation	0.9	1.2	3.3	-1.4	-1.2	-1.5	-1.3	0.7	0.4	1.8	-1.0	-0.6	-0.5	-0.9	-1.2	-1.5	0.4	0.5	-1.1
Eye problems/disorders: Glaucoma	0.9	1.1	3.8	0.3	0.6	0.4	0.5	1.5	1.4	1.9	0.7	0.5	1.0	0.6	0.6	0.4	1.6	1.7	0.6
Irritability	0.9	1.6	3.5	-1.4	-1.6	-1.8	-1.7	0.1	0.1	0.9	-1.6	-1.1	-0.5	-1.2	-1.4	-1.9	-0.4	0.9	-1.3
Medication: Levothyroxine sodium	0.8	1.3	3.4	-0.8	-0.8	-0.9	-0.8	-1.3	-1.6	-1.1	-1.1	-1.7	-1.8	-0.9	-0.9	-0.8	-1.2	-1.0	-1.1
Trunk fat mass	0.8	3.4	13.5	1.9	2.1	1.8	2.2	1.1	1.6	-0.5	1.1	3.7	2.0	2.2	1.8	2.1	0.7	-0.9	1.6
Happiness	0.8	0.9	2.3	-0.6	-0.8	-0.4	-0.8	-0.6	-0.8	-0.2	-0.9	-1.5	-1.5	-1.3	-1.1	-0.7	-0.6	-1.4	-1.0
Length of working week for main job	0.8	0.9	2.3	0.5	1.0	1.5	0.9	0.5	0.9	0.0	1.5	1.2	1.0	0.9	0.8	1.1	0.6	0.0	1.0
Worry too long after embarrassment	0.8	1.4	3.5	-1.1	-1.3	-1.7	-1.4	-0.3	0.7	0.7	-0.4	-1.9	-0.6	-1.3	-1.5	-1.6	-0.4	0.9	-1.6
Wheeze or whistling in the chest in last year	0.8	1.4	3.1	-1.8	-1.3	-1.7	-1.3	-0.5	-0.4	-0.3	-1.4	-1.2	-1.1	-1.2	-1.2	-1.4	-0.8	-0.5	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.3	1.5	1.3	1.2	1.4	-0.4	0.0	-1.0	1.2	0.4	0.7	1.0	1.0	1.2	-0.0	-0.1	1.1
Mean time to correctly identify matches	0.8	1.4	4.2	-1.0	-0.9	-1.3	-1.0	-1.1	-2.1	-1.7	-0.8	-1.5	-1.3	-1.1	-0.6	-1.1	-1.5	0.1	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	3.1	1.5	1.4	1.8	1.6	0.1	0.6	-1.0	1.3	1.5	1.5	1.4	1.2	1.6	0.0	-0.8	1.4
Verbal and Numeric Reasoning (VNR)	0.7	1.7	4.0	1.3	1.6	1.5	1.7	0.6	2.0	0.0	2.0	-0.0	0.5	1.1	1.4	1.6	0.9	1.2	1.2
Blood Eosinophil Count	0.7	5.1	9.1	-3.0	-2.6	-2.2	-2.8	-1.9	-0.7	-0.7	-1.6	-1.9	-1.7	-2.6	-2.9	-2.8	-2.1	-2.2	-2.5
Fed-up feelings	0.7	1.2	2.4	-1.1	-1.6	-1.4	-1.4	0.3	1.0	1.1	-1.3	-0.5	-0.5	-1.1	-1.3	-1.5	-0.2	-0.2	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	1.9	-1.0	-1.4	-1.3	-1.3	-0.3	-0.7	0.2	-1.4	-1.1	-1.1	-1.1	-1.2	-1.2	-0.6	-0.5	-1.4
Fluid intelligence score	0.7	1.4	4.2	1.4	1.4	1.5	1.5	0.2	1.7	-0.4	2.1	-0.0	0.8	0.9	1.1	1.4	0.4	0.3	1.2
Impedance of arm (right)	0.7	3.4	6.6	-1.7	-2.2	-2.2	-1.9	0.5	-1.9	2.0	-2.6	-2.2	-2.2	-2.0	-1.0	-1.8	0.5	1.6	-1.6
Time employed in main current job	0.7	0.8	2.3	-0.1	-0.6	-0.9	-0.5	-1.0	-1.5	-1.5	-0.6	-0.9	-0.9	-0.6	-0.4	-0.6	-1.4	-0.5	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	3.0	-1.1	-1.3	-1.4	-1.2	0.4	0.5	1.1	-1.4	-0.3	-0.7	-0.8	-1.3	-1.1	-0.0	-1.2	-1.7
Falls in the last year	0.7	0.9	1.6	-1.1	-1.1	-0.9	-1.1	-0.5	-0.8	-0.2	-1.2	-0.4	-0.8	-1.1	-1.2	-1.1	-0.8	-0.9	-1.3
Commuting to job workplace: Car/motor vehicle	0.7	0.8	4.6	-0.7	-0.4	-0.5	-0.5	-0.9	-1.4	-0.3	-0.9	-0.2	-0.9	-0.6	-0.9	-0.4	-0.4	-2.1	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	2.9	-1.1	-0.9	-1.2	-1.2	-0.9	-0.5	-0.6	-0.8	-1.7	-1.4	-1.1	-1.2	-1.0	-0.9	-0.6	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	3.0	-1.2	-0.8	-0.7	-1.1	-0.1	0.1	1.0	-0.6	0.7	-0.1	-0.9	-1.3	-0.9	0.0	-1.7	-1.4
Supplements: Fish oil (including cod liver oil)	0.7	0.9	1.8	-1.2	-0.8	-0.9	-0.9	-0.9	-0.7	0.3	-1.2	0.2	-0.9	-0.8	-1.1	-0.8	-0.4	-1.4	-1.3
Prostate Cancer	0.6	0.8	1.7	1.3	0.6	0.9	0.7	1.1	1.3	1.2	0.1	0.9	0.3	0.8	0.8	0.8	1.2	0.1	0.9
Coronary Artery Disease (CAD)	0.6	0.7	1.4	-0.8	-0.8	-0.6	-0.9	-0.3	-1.0	-1.2	-1.1	-0.8	-1.1	-1.0	-0.5	-0.8	-1.1	-0.1	-0.3
Chronotype (morning person)	0.6	1.4	5.5	0.1	0.5	1.0	0.4	1.4	2.3	2.4	1.1	-0.4	0.8	0.4	0.4	0.5	1.8	1.0	0.9
Medication for hormone replacement therapy	0.6	0.6	2.6	-0.0	0.6	1.3	0.6	0.4	0.2	0.1	0.2	1.6	0.3	0.7	0.4	0.8	0.3	-1.6	0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.5	2.7	1.3	1.6	1.2	1.5	0.1	0.9	-1.5	1.6	1.0	0.7	1.2	1.5	1.4	-0.0	0.3	1.5
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.6	0.7	0.8	0.4	0.8	1.0	0.7	0.5	0.6	1.3	1.0	1.0	0.8	0.7	0.8	0.4	0.6
Supplements: Glucosamine	0.6	0.8	2.9	0.8	0.8	0.8	0.8	0.9	1.7	0.2	0.9	1.0	1.0	0.7	0.9	0.9	0.5	-0.3	0.7
Had other major operations	0.6	0.7	8.1	-0.8	-0.4	0.9	-0.2	-0.4	-0.7	-0.1	-0.4	0.3	-0.2	-0.0	-0.5	0.2	-0.2	-2.8	-0.1
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	4.2	0.2	0.3	0.5	0.5	1.3	0.7	2.1	-0.1	0.9	0.4	0.4	0.3	0.5	1.6	0.2	0.2
Qualifications: None of the above	0.6	1.3	5.2	1.0	0.9	1.1	0.8	1.4	0.4	1.3	0.7	2.3	1.3	1.2	0.9	1.0	1.4	-0.2	1.0
Impedance of arm (left)	0.6	2.8	6.5	-1.5	-1.8	-1.9	-1.5	1.2	-1.7	2.5	-2.2	-1.7	-1.8	-1.6	-0.6	-1.4	1.1	2.0	-1.3
Forced vital capacity (FVC), Best measure	0.6	2.2	3.0	1.5	1.6	1.6	1.5	1.2	1.7	1.0	1.7	1.5	1.7	1.6	1.3	1.5	1.6	1.1	1.4
Qualifications: College or University degree	0.6	1.8	4.6	-1.2	-1.0	-1.3	-1.0	-1.6	-1.5	-1.4	-0.7	-2.1	-1.5	-1.6	-1.1	-1.4	-1.6	-0.0	-0.9
Leg fat mass (right)	0.6	2.4	8.1	1.5	1.9	1.5	1.9	0.7	1.5	-0.5	1.1	2.8	1.6	2.0	1.5	1.8	0.6	-0.7	1.3
Back pain experienced in last month	0.6	0.8	2.5	-0.7	-1.2	-0.6	-1.1	-0.4	-0.6	1.1	-1.1	-0.2	-0.2	-0.4	-1.3	-1.0	-0.0	-1.6	-1.0
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.8	1.4	1.0	1.0	1.0	0.5	0.7	0.1	0.8	1.1	1.0	1.1	0.9	1.2	0.6	-0.5	0.6
Diastolic blood pressure, automated reading	0.6	2.0	8.5	-1.4	-0.9	-0.6	-0.8	-1.6	-1.2	-1.4	-1.4	-1.3	-1.9	-0.9	-1.2	-0.6	-1.4	-2.9	-1.4
Heart disease (siblings)	0.6	0.7	1.9	-1.1	-0.9	-1.1	-1.0	0.5	-0.2	1.4	-0.5	-0.8	-0.3	-0.8	-0.9	-0.9	0.4	0.1	-1.2
Leg fat mass (left)	0.6	2.2	8.0	1.5	1.8	1.5	1.7	0.5	1.4	-0.7	1.0	2.8	1.6	1.8	1.3	1.6	0.3	-1.0	1.2
Depressed Affect (Nagel 2018)	0.5	1.1	2.4	-1.2	-1.5	-1.1	-1.4	0.4	-0.2	1.2	-1.6	-0.2	-0.7	-1.0	-1.3	-1.3	-0.1	-0.6	-1.1
Depression (Nagel 2018)	0.5	0.7	1.9	-0.6	-1.3	-0.6	-1.1	0.2	-0.7	1.0	-1.4	-0.3	-0.7	-0.8	-1.0	-1.0	-0.0	-0.8	-0.9
Alzheimer’s Disease (in mother)	0.5	0.6	1.7	-1.3	-0.4	-0.7	-0.5	0.5	0.0	1.2	-0.4	-1.3	-0.7	-0.6	-0.5	-0.7	0.6	0.6	-0.5
Hypothyroidism (self reported)	0.5	1.1	3.2	-0.4	-0.7	-1.1	-0.8	-1.3	-1.0	-0.8	-0.7	-1.8	-1.6	-0.8	-0.9	-0.8	-1.0	-0.4	-1.3
Lung FVC	0.5	2.3	6.3	-1.6	-1.5	-1.7	-1.5	-0.6	-1.3	-0.5	-1.6	-2.5	-2.5	-1.7	-1.3	-1.4	-0.9	-0.2	-1.6
Supplements: Zinc	0.5	0.6	2.8	-0.0	0.3	0.3	0.2	-1.6	-1.0	-1.7	-0.1	-0.1	-0.6	-0.0	-0.0	0.3	-1.0	-1.1	-0.1
Hair/balding pattern: Pattern 2	0.5	0.6	1.8	-0.8	-0.5	-0.9	-0.8	0.1	0.7	1.4	-0.6	-0.2	-0.5	-0.8	-1.0	-0.8	0.4	0.1	-1.2
Forced vital capacity (FVC)	0.5	1.9	3.6	1.7	1.4	1.4	1.4	1.2	1.9	0.9	1.5	1.6	1.6	1.4	1.1	1.4	1.3	0.4	1.2
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	3.1	-0.7	-0.9	-1.0	-0.8	-0.2	-1.8	-0.3	-0.4	-0.9	-0.7	-1.0	-0.8	-0.9	-0.7	-0.0	-1.0
Forced expiratory volume in 1-second (FEV1)	0.5	1.5	4.8	1.0	0.7	1.0	0.7	1.8	2.2	2.0	1.1	1.0	1.4	0.9	0.5	0.7	1.7	0.5	0.8
Lung cancer (father)	0.5	0.6	2.0	-0.8	-0.8	-1.3	-0.8	0.6	0.9	0.5	-0.8	-0.3	-0.0	-0.5	-0.4	-0.9	-0.0	1.4	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	2.9	0.9	0.9	1.2	0.9	1.5	1.7	1.7	1.4	1.0	1.5	1.1	0.8	0.9	1.6	1.0	1.0
Ever highly irritable/argumentative for 2 days	0.5	0.6	3.2	-0.2	-0.5	0.2	-0.5	0.8	0.6	1.8	-0.6	-0.2	-0.3	-0.3	-0.8	-0.3	0.8	-1.4	-0.4
Neck or shoulder pain in last month	0.5	0.8	5.8	-0.1	-0.6	-0.6	-0.5	-0.7	-0.7	-0.7	-1.1	0.5	-0.1	-0.1	-0.7	-0.4	-0.9	-2.4	-0.9
Whole body fat mass	0.5	2.2	9.3	1.5	1.7	1.4	1.8	0.7	1.4	-0.7	0.8	3.0	1.6	1.9	1.4	1.6	0.4	-0.9	1.2
Leg pain on walking	0.5	0.7	2.5	0.5	0.7	0.3	0.7	0.8	0.6	1.6	0.3	1.2	0.7	1.0	0.3	0.7	1.3	-0.5	-0.2
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	4.0	-0.2	0.2	-0.1	0.4	-1.6	-1.0	-2.0	0.0	-0.5	-0.6	0.2	0.5	0.2	-1.0	0.4	0.3
Smoking status: Previous	0.5	0.7	4.4	0.2	0.2	-0.3	-0.1	-1.2	-2.1	-1.8	-0.7	0.0	-0.8	-0.2	0.1	0.1	-1.0	-0.5	-0.3
Financial situation satisfaction	0.5	0.6	3.7	-0.7	-0.5	0.1	-0.6	-0.9	-1.0	-0.1	-0.7	-0.1	-0.7	-0.7	-0.8	-0.3	-0.4	-1.9	-0.6
Alcohol drinker status: Never	0.5	0.6	3.3	-0.6	0.0	-0.1	-0.1	1.2	1.5	1.8	-0.1	0.5	0.2	0.2	-0.1	-0.0	1.3	0.8	-0.2
Risk taking	0.5	0.8	7.3	0.5	0.5	0.6	0.5	0.6	0.3	0.2	0.5	2.7	1.4	0.6	0.4	0.6	0.3	-0.6	0.3
Commuting to job workplace: Cycle	0.5	0.5	1.4	0.4	0.5	0.8	0.7	0.5	0.4	1.1	0.9	1.2	1.1	0.6	0.2	0.7	0.8	-0.8	0.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.5	-0.9	-0.9	-1.2	-0.9	0.1	-0.9	0.5	-0.6	-0.8	-0.4	-0.4	-0.8	-0.9	-0.1	-0.2	-1.2
Pack years of smoking	0.5	0.7	1.6	0.5	0.7	1.3	0.7	0.5	0.6	1.0	0.6	1.0	1.1	1.0	0.5	1.0	1.1	-0.7	0.7
Impedance of whole body	0.5	2.6	10.0	-1.3	-1.4	-1.4	-1.3	1.4	-1.5	3.2	-1.7	-1.7	-1.5	-1.4	-0.4	-1.1	1.7	2.3	-1.0
LDL Cholesterol	0.4	0.7	2.6	-0.4	-0.5	-1.0	-0.4	0.7	-0.2	1.4	-0.6	-1.6	-1.1	-0.6	-0.2	-0.5	0.8	1.1	-0.6
Severe depression (siblings)	0.4	0.5	2.4	-0.5	-0.1	-0.5	-0.2	-1.4	-0.3	-1.5	-0.0	0.3	-0.4	-0.4	-0.4	-0.3	-1.2	-0.7	-0.6
Impedance of leg (right)	0.4	1.8	11.7	-0.4	-0.1	-0.1	-0.1	1.8	-0.4	3.4	-0.2	-1.1	-0.5	-0.2	0.4	-0.0	2.4	2.5	0.1
Impedance of leg (left)	0.4	1.7	12.0	-0.6	-0.5	-0.4	-0.6	1.6	-0.6	3.5	-0.6	-1.2	-0.6	-0.7	-0.0	-0.4	2.2	2.1	-0.2
Number of incorrect matches in round	0.4	0.6	3.3	0.8	0.6	0.3	0.5	-1.1	-1.1	-1.8	0.2	1.2	0.1	0.3	0.6	0.6	-0.9	-0.2	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	2.1	1.1	1.4	1.1	1.3	-0.2	0.5	-1.4	1.2	0.6	0.1	1.1	1.2	1.3	-0.2	-0.3	1.1
Mouth/teeth dental problems	0.4	0.6	2.5	0.1	-0.2	-1.1	0.1	-0.8	-1.6	-1.4	-0.4	0.3	-0.1	-0.2	0.1	-0.4	-1.1	0.5	-0.5
Hip circumference	0.4	1.9	9.0	1.0	1.3	1.5	1.3	-0.0	1.4	-1.6	0.7	3.0	1.2	1.2	0.8	1.3	-0.5	-1.9	0.9
Father’s age at death	0.4	0.5	1.2	-0.7	-0.5	-0.7	-0.5	-0.8	-1.1	-0.9	-0.6	-1.1	-0.8	-0.5	-0.4	-0.8	-0.9	-0.1	-0.2
Noisy workplace	0.4	0.4	1.3	0.6	0.7	0.2	0.7	0.8	0.1	1.1	0.6	0.7	0.6	0.6	0.6	0.6	1.0	0.6	0.1
Arm fat mass (right)	0.4	1.6	7.0	1.2	1.4	1.0	1.5	0.3	1.5	-1.1	0.6	2.6	1.2	1.6	1.0	1.3	-0.1	-1.2	0.7
Exposure to tobacco smoke at home	0.4	0.5	2.9	-0.3	-0.2	-0.4	-0.1	-1.1	-0.6	-1.7	-0.3	-0.5	-0.7	-0.5	-0.2	-0.2	-1.2	-0.5	-0.5
Birth weight	0.4	0.9	4.0	-0.9	-0.5	-0.2	-0.4	-1.1	-0.8	-1.2	-1.2	-0.2	-0.9	-0.5	-0.7	-0.4	-1.2	-2.0	-0.6
Pulse wave peak to peak time	0.4	0.4	1.2	0.8	0.7	0.4	0.5	-0.6	0.2	-0.9	1.1	0.3	0.7	0.5	0.7	0.6	-0.2	1.0	0.5
Emphysema/chronic bronchitis	0.4	0.4	1.4	0.3	0.9	0.6	0.9	0.4	1.2	0.3	0.7	0.2	0.4	0.8	0.6	0.9	0.8	0.3	0.3
Migraine (self-reported)	0.4	0.5	4.5	-0.5	-0.3	0.3	-0.2	0.8	-0.2	2.1	-0.2	-0.2	-0.2	-0.0	-0.4	-0.0	1.4	-0.2	-0.3
Suffer from ‘nerves’	0.4	0.6	3.6	0.4	0.1	-0.2	0.1	1.2	1.3	1.9	0.4	-0.1	0.4	0.1	-0.2	0.0	1.2	0.4	-0.4
Knee pain experienced in last month	0.4	0.6	2.4	1.2	0.6	0.9	0.7	0.3	-0.1	0.4	0.5	1.6	0.9	1.0	0.7	0.9	0.7	-0.5	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	0.9	-0.8	-0.8	-0.3	-0.9	-0.1	-0.8	-0.1	-0.5	-1.0	-0.5	-0.8	-0.9	-0.8	-0.5	-0.2	-0.4
Illnesses of siblings: Diabetes	0.4	0.4	3.0	0.6	0.1	-0.3	0.1	-0.9	-0.6	-1.7	0.3	-0.2	0.4	0.1	-0.1	-0.3	-1.3	0.0	0.1
Osteoarthritis (self-reported)	0.4	0.5	2.6	-0.1	0.3	0.6	0.3	-1.0	-0.6	-1.4	0.1	0.8	-0.2	0.2	0.1	0.5	-0.6	-1.6	-0.0
Arm fat mass (left)	0.4	1.7	7.5	1.2	1.4	1.1	1.5	0.4	1.6	-0.9	0.6	2.7	1.3	1.6	1.0	1.4	0.0	-1.2	0.7
Guilty feelings	0.4	0.7	3.4	0.5	-0.2	0.2	-0.1	1.5	1.4	1.8	0.3	0.6	1.0	0.2	-0.2	-0.1	1.0	0.2	-0.0
Age started oral contraceptive pill	0.4	0.6	5.8	-0.4	0.2	-0.0	0.2	0.9	0.0	0.5	0.7	-0.6	0.4	0.2	0.5	0.0	0.6	2.4	0.6
Ever depressed for a whole week	0.4	0.5	2.2	0.4	0.7	0.5	0.6	0.9	1.0	1.5	0.2	0.5	0.3	0.6	0.4	0.5	1.4	0.5	0.3
HbA1C	0.3	0.3	1.2	0.0	0.4	0.4	0.4	0.6	0.1	0.5	0.6	0.6	0.4	0.6	0.6	0.6	0.8	1.1	0.3
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.5	0.4	0.8	0.1	0.6	-0.7	-0.5	-1.2	0.5	0.8	0.4	0.8	0.5	0.5	-0.3	0.6	0.3
Heel T-Score	0.3	2.2	5.1	1.7	1.9	1.1	1.7	1.2	0.7	-0.7	1.3	2.2	1.2	1.9	2.0	1.6	0.6	0.9	1.7
Medication: Co-codamol	0.3	0.3	1.2	-0.1	-0.2	-0.0	-0.3	-0.4	0.9	0.8	0.3	0.5	0.5	-0.4	-0.5	0.0	0.4	-1.1	-0.8
Current tobacco smoking	0.3	0.4	1.2	-0.6	-0.8	-0.8	-0.8	0.7	0.7	1.1	-0.4	0.1	0.3	-0.5	-0.7	-0.7	0.3	-0.4	-0.9
Past tobacco smoking	0.3	0.5	3.4	-0.2	-0.1	0.2	0.3	0.7	1.8	1.3	0.6	-0.1	0.7	0.2	0.1	-0.1	0.8	0.9	0.3
Financial difficulties in last 2 years	0.3	0.4	1.4	0.5	0.4	-0.0	0.2	0.7	1.2	1.1	0.5	0.7	0.6	0.3	0.3	0.4	0.9	-0.2	-0.3
Tense / ‘highly strung’	0.3	0.6	3.2	-0.3	-0.7	-0.7	-0.8	0.9	0.3	1.8	-0.7	0.2	0.4	-0.3	-0.6	-0.9	0.7	0.8	-0.4
Peak expiratory flow (PEF)	0.3	0.7	4.0	-0.4	-0.6	-0.6	-0.5	1.1	1.1	2.0	-0.3	0.0	0.4	-0.2	-0.8	-0.6	0.8	-0.8	-0.9
Exposure to tobacco smoke outside home	0.3	0.4	2.2	-0.1	-0.4	0.4	-0.3	0.2	1.5	1.2	-0.0	-0.0	0.2	-0.3	-0.6	-0.2	0.3	-1.1	-0.1
Shortness of breath walking on level ground	0.3	0.4	2.1	0.5	0.5	0.3	0.5	0.9	0.1	0.8	0.5	1.4	0.7	0.5	0.4	0.3	0.8	0.6	0.3
Had major operations	0.3	0.3	0.7	-0.9	-0.3	-0.8	-0.4	-0.2	-0.5	0.3	-0.7	-0.6	-0.8	-0.2	-0.5	-0.5	-0.0	-0.2	-0.7
Average weekly red wine intake	0.3	0.5	2.6	0.7	0.6	0.3	0.7	-0.7	-1.6	-1.2	0.5	0.3	0.3	0.7	0.4	0.5	-0.6	-0.4	0.3
Long-standing illness, disability or infirmity	0.3	0.5	1.8	-0.4	-0.6	-1.0	-0.7	-0.1	-1.2	0.6	-0.5	0.2	-0.1	-0.5	-0.9	-0.7	-0.1	-0.8	-1.4
Myopia	0.3	0.5	1.8	0.6	0.4	1.3	0.5	0.4	0.6	-0.2	0.3	1.4	0.7	0.4	0.5	0.7	0.1	-0.5	1.0
Supplements: Calcium	0.3	0.3	1.2	-0.7	-0.3	0.2	-0.4	-0.6	-0.9	-0.2	-0.6	-0.4	-0.7	-0.3	-0.5	-0.1	-0.2	-1.1	-0.5
Basal cell carcinoma (self-reported)	0.3	0.3	1.1	-0.7	-0.7	-0.4	-0.6	-0.7	0.1	0.1	-0.2	-0.7	-0.0	-0.6	-0.8	-0.6	-0.4	-1.1	-0.6
Alcohol drinker status: Previous	0.3	0.3	2.3	-0.4	-0.4	-0.6	-0.4	-0.7	-1.5	-0.7	-0.6	-0.0	-0.2	-0.2	-0.1	-0.2	-0.5	0.4	-0.6
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.5	0.4	0.6	0.9	0.7	0.5	1.6	0.4	1.1	-1.1	-0.3	0.2	0.6	0.7	0.7	1.0	0.7
Neuroticism (Nagel 2018)	0.2	0.6	3.5	0.2	-0.6	-0.1	-0.5	1.3	0.6	1.9	-0.3	0.5	0.9	0.1	-0.4	-0.4	0.9	0.5	-0.1
Alzheimer’s Disease (in father)	0.2	0.3	1.3	0.1	-0.1	0.4	-0.1	-0.7	-0.3	-1.1	-0.5	0.2	-0.0	-0.0	0.0	0.0	-0.8	-0.9	0.5
Blood Red Count	0.2	2.3	7.6	-1.7	-0.9	-0.6	-0.9	-1.9	0.0	-1.4	-0.7	-2.0	-1.5	-0.9	-2.0	-1.4	-1.8	-2.8	-1.1
BMI	0.2	1.2	4.0	0.9	0.8	0.7	0.9	-0.6	1.1	-1.9	-0.1	2.0	0.9	1.1	0.4	0.7	-1.0	-1.6	0.6
Lung FEV1/FVC ratio	0.2	1.1	4.3	0.4	0.1	1.0	0.2	2.1	1.7	1.9	1.2	-0.3	1.0	0.4	0.3	0.4	1.3	0.4	0.8
Ever had hysterectomy (womb removed)	0.2	0.2	0.9	-0.7	-0.3	-0.6	-0.3	0.0	-0.9	0.1	-0.6	-0.7	-0.9	-0.1	-0.2	-0.3	0.0	-0.0	-0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.2	0.5	0.4	-0.4	0.2	-1.1	-0.3	-0.9	0.3	0.5	0.0	0.3	0.1	0.1	-0.6	-0.1	-0.3
Pack years adult smoking proportion	0.2	0.3	1.3	-0.0	0.1	0.8	0.1	0.2	0.5	1.0	0.1	0.7	0.8	0.5	-0.0	0.5	0.7	-1.1	0.2
Average weekly fortified wine intake	0.2	0.3	0.9	0.4	0.6	0.9	0.6	0.0	0.1	0.1	0.3	0.3	0.4	0.6	0.5	0.5	0.4	0.6	0.9
Maternal smoking around birth	0.2	0.3	0.9	0.2	0.5	0.1	0.5	0.8	-0.3	-0.2	-0.2	0.9	0.4	1.0	0.8	0.6	0.4	0.4	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.7	-0.3	-0.9	-0.4	-0.8	0.2	-0.4	0.5	-0.7	-0.1	-0.3	-0.6	-0.7	-0.6	-0.1	-0.5	-0.7
Medication: Atenolol	0.2	0.2	1.0	-0.1	-0.5	-0.6	-0.4	0.7	-0.1	1.0	-0.2	-0.2	0.2	-0.3	-0.5	-0.5	0.3	0.0	-0.6
Chronic bronchitis/emphysema (father)	0.2	0.2	0.9	-0.1	-0.3	-0.0	-0.3	0.8	-0.3	0.8	-0.9	0.3	-0.4	0.0	-0.1	-0.2	0.4	-0.1	0.1
Body mass index (BMI)	0.2	0.7	3.5	0.1	0.4	0.2	0.4	-0.5	0.7	-1.5	-0.1	1.6	0.3	0.5	-0.1	0.3	-0.9	-1.9	-0.1
Prospective memory result	0.2	0.2	0.7	0.5	0.4	0.5	0.3	-0.7	-0.7	-0.3	0.3	0.8	0.5	0.2	0.4	0.5	0.1	-0.3	0.3
Pulse wave Arterial Stiffness index	0.2	0.2	0.9	-0.4	-0.2	0.2	-0.1	0.8	0.2	0.9	-0.7	0.2	-0.2	-0.0	-0.3	-0.1	0.5	-0.9	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	0.8	-0.1	0.6	0.9	0.5	0.7	0.7	0.7	0.3	0.7	-0.0	0.4	0.3	0.7	0.8	-0.8	0.3
Loud music exposure frequency	0.2	0.2	1.1	0.7	0.2	0.1	0.4	0.1	0.1	0.3	-0.4	1.1	0.5	0.5	0.3	0.4	0.4	0.1	-0.0
Medication: Seretide 50 evohaler	0.2	0.2	1.1	0.0	0.4	0.0	0.5	-0.4	-0.7	-1.0	0.4	-0.2	-0.1	0.2	0.4	0.4	-0.4	0.3	0.0
Asthma (self-reported)	0.2	0.5	1.7	-0.4	-0.2	-1.1	-0.1	-1.0	-1.3	-1.0	-0.6	-0.4	-0.6	-0.1	-0.1	-0.5	-0.7	0.3	-0.8
Illnesses of father: None of the above (group 1)	0.2	0.3	1.3	-0.5	-0.4	-0.6	-0.4	-0.6	0.4	-1.1	0.2	-0.2	-0.2	-0.4	-0.3	-0.4	-0.9	0.4	-0.4
Smoking status: Current	0.2	0.3	1.4	-0.3	-0.4	-0.5	-0.5	1.1	0.9	1.2	-0.1	0.2	0.4	-0.2	-0.4	-0.3	0.6	-0.3	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	2.1	-0.5	-0.6	-0.6	-0.6	-0.1	-0.6	0.3	-0.4	-1.4	-0.9	-0.5	-0.4	-0.5	-0.0	0.4	-0.5
Wears glasses or contact lenses	0.2	0.3	1.0	-0.7	-0.2	-0.4	-0.3	-0.4	-0.8	-1.0	-0.4	0.1	-0.3	-0.3	-0.3	-0.4	-0.9	-0.5	-0.4
Medication: Bendroflumethiazide	0.2	0.2	1.5	-0.0	-0.4	-0.1	-0.5	0.1	0.6	0.6	-0.6	-0.3	-0.3	-0.4	-0.5	-0.3	0.1	-1.2	-0.5
Medication: Lisinopril	0.2	0.2	0.6	-0.5	-0.4	-0.8	-0.4	-0.7	0.1	-0.1	-0.5	0.0	-0.0	-0.2	-0.5	-0.5	-0.3	-0.0	-0.8
Ever smoked	0.2	0.4	1.8	0.3	-0.0	-0.1	-0.3	-0.7	-1.4	-1.1	-0.3	0.3	-0.4	-0.4	-0.3	0.0	-0.7	-1.2	-0.5
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.7	-0.8	-0.2	-0.3	-0.2	-0.4	-0.1	-0.9	-0.7	-0.5	-0.7	-0.2	-0.2	-0.3	-0.7	-0.7	-0.2
Worry (Nagel 2018)	0.1	0.3	2.0	0.1	-0.6	-0.4	-0.5	0.4	0.3	1.4	-0.2	-0.1	0.6	-0.2	-0.6	-0.6	0.5	0.1	-0.4
Alzheimer’s Disease (including proxy)	0.1	0.1	0.3	-0.2	0.2	0.3	0.2	0.4	0.1	0.5	-0.1	-0.4	-0.1	0.1	0.2	0.1	0.5	0.5	0.5
Breast Cancer	0.1	0.2	0.9	-0.6	0.2	0.2	0.3	0.8	0.2	1.0	0.1	-0.2	-0.3	0.1	0.3	0.2	0.9	-0.1	0.2
Mean Putamen Volume	0.1	0.2	1.8	0.0	0.2	0.1	0.1	0.1	-0.0	0.3	0.2	-0.3	-0.2	-0.1	0.2	-0.0	0.3	1.3	0.4
Rheumatoid Arthritis	0.1	0.2	0.4	0.7	0.4	0.5	0.5	0.1	-0.0	-0.5	0.4	0.2	0.2	0.3	0.6	0.5	0.0	0.6	0.5
Smoking Status	0.1	0.2	0.8	0.1	-0.3	-0.5	-0.5	-0.2	-0.5	-0.9	-0.7	-0.1	-0.5	-0.4	-0.1	-0.2	-0.5	-0.2	-0.4
Respiratory disease	0.1	0.1	0.8	-0.1	-0.1	-0.9	-0.1	-0.1	-0.6	-0.1	-0.5	-0.2	-0.1	0.1	0.0	-0.4	-0.1	0.7	-0.4
Average weekly spirits intake	0.1	0.1	0.7	-0.5	0.2	0.2	0.0	0.0	0.7	0.5	-0.2	0.8	0.2	-0.0	0.0	0.2	0.4	-0.1	-0.2
Sensitivity / hurt feelings	0.1	0.2	0.6	-0.4	-0.5	-0.4	-0.6	0.1	-0.2	0.4	-0.4	0.3	0.2	-0.2	-0.8	-0.5	-0.2	-0.7	-0.8
Trunk fat percentage	0.1	0.5	4.6	0.3	0.6	0.4	0.7	0.8	0.3	0.0	-0.4	2.1	0.5	0.7	0.6	0.6	0.3	-0.8	0.2
Qualifications: CSEs or equivalent	0.1	0.1	0.6	0.4	-0.1	0.3	-0.1	-0.6	-0.3	-0.8	-0.2	0.3	-0.1	-0.1	-0.1	0.1	-0.6	-0.7	-0.1
Nervous feelings	0.1	0.2	1.7	0.4	-0.3	-0.1	-0.2	0.5	0.3	1.3	0.0	-0.3	0.6	0.1	-0.1	-0.2	0.8	0.7	-0.0
Arm fat percentage (right)	0.1	0.4	1.2	-0.5	-0.3	-0.8	-0.1	-0.1	0.2	-0.6	-1.1	0.9	-0.5	-0.1	-0.3	-0.3	-0.5	-1.1	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.7	0.3	0.4	0.6	0.3	-0.1	0.1	-0.8	0.0	-0.4	-0.6	0.0	0.2	0.5	-0.2	-0.4	0.1
Asthma	0.1	0.3	1.1	-0.2	0.1	-0.9	0.2	-0.7	-1.1	-0.8	-0.3	-0.2	-0.3	0.3	0.2	-0.2	-0.4	0.7	-0.5
Depression (self-reported)	0.1	0.1	0.5	0.1	0.2	0.3	0.2	0.3	-0.1	0.4	0.7	-0.2	0.4	0.1	0.3	0.3	0.6	0.7	0.1
Medication: Lansoprazole	0.1	0.1	0.4	-0.6	-0.4	0.2	-0.5	0.5	0.0	0.5	-0.6	0.2	-0.3	-0.3	-0.3	-0.3	0.1	-0.6	0.2
Blood clot in the leg (DVT)	0.1	0.2	1.0	-0.3	0.1	-0.1	0.3	-0.0	-0.4	-0.4	-0.7	-0.3	-0.5	0.3	-0.1	0.1	-0.3	-1.0	-0.3
Body fat percentage	0.1	0.3	2.5	-0.1	0.2	-0.1	0.3	0.6	0.3	0.2	-0.7	1.6	0.1	0.4	0.2	0.2	0.2	-0.8	-0.2
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.8	-0.4	-0.2	0.3	-0.1	0.5	0.1	0.9	-0.4	0.0	-0.1	-0.1	-0.1	0.1	0.6	-0.4	0.1
Medication: Omeprazole	0.1	0.2	0.5	-0.3	-0.3	-0.7	-0.3	0.2	-0.7	0.4	-0.2	0.1	0.3	0.1	-0.4	-0.4	0.0	-0.5	-0.7
Number of full sisters	0.1	0.1	0.8	0.2	-0.1	-0.1	0.0	0.9	-0.5	0.4	-0.1	-0.7	-0.1	-0.0	-0.0	-0.1	0.2	0.1	0.1
Age at last live birth	0.1	0.2	0.8	-0.6	0.1	0.1	0.0	-0.6	-0.3	-0.9	0.3	-0.7	-0.4	-0.3	-0.0	-0.0	-0.5	-0.5	0.1
Arm fat percentage (left)	0.1	0.3	1.3	-0.3	-0.2	-0.6	0.0	0.2	0.2	-0.4	-1.0	1.2	-0.3	0.1	-0.2	-0.1	-0.3	-0.9	-0.7
Friendships satisfaction	0.1	0.1	0.9	-0.3	-0.0	0.2	-0.1	-0.1	0.4	0.1	-0.2	-1.0	-0.7	-0.4	-0.4	-0.1	0.1	-0.5	-0.2
Commuting to job workplace: Walk	0.1	0.1	0.8	0.4	0.0	0.5	0.2	0.0	-0.2	0.0	0.3	-0.5	0.0	-0.1	0.1	0.1	0.1	0.9	0.4
Mineral and other dietary supplements	0.1	0.2	0.7	0.5	-0.0	0.3	-0.0	0.3	-0.1	-0.4	0.4	-0.7	0.2	0.1	0.3	-0.0	-0.2	0.8	0.7
Average weekly champagne plus white wine intake	0.1	0.2	1.2	0.2	0.2	-0.1	0.2	-0.3	0.1	-1.1	0.6	-0.0	0.3	0.3	0.2	0.1	-0.5	0.7	0.3
Leg fat percentage (left)	0.1	0.2	1.3	-0.3	0.0	-0.2	-0.0	0.2	0.1	-0.0	-0.7	1.1	-0.2	0.0	-0.2	-0.1	-0.1	-1.1	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.7	-0.2	0.2	-0.1	0.4	0.1	-0.3	-0.3	-0.6	-0.1	-0.3	0.4	0.0	0.2	-0.2	-0.8	-0.3
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.5	0.0	0.2	-0.3	-0.0	-0.4	-0.4	-0.4	0.1	-0.4	-0.7	-0.0	-0.0	-0.0	-0.2	0.2	-0.4
Leg fat percentage (right)	0.0	0.2	1.2	-0.2	0.3	-0.1	0.3	0.4	0.2	0.1	-0.5	1.1	-0.2	0.3	0.1	0.1	0.2	-0.7	-0.2
Breast cancer (self-reported)	0.0	0.1	0.2	-0.3	-0.2	-0.1	-0.2	-0.2	-0.3	0.3	-0.1	-0.4	0.0	-0.2	-0.3	-0.3	0.1	-0.2	-0.1

Hub : Genes

KRTCAP3

Models

Trait associations