[Hub]/) : Traits : Height : ← →

chr6:41,005,502-46,043,561

Best TWAS P=5.11e-59 · Best GWAS P=6.83e-45 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CUL7	0.06	0.05	lasso	2	0.04	7.5e-06	-6.47	6.2	6.0e-10	-0.04	0.70	0.06	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CUL9	0.15	0.12	bslmm	386	0.14	3.1e-16	-6.77	7.8	8.7e-15	0.01	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	MED20	0.15	0.11	blup	471	0.13	3.1e-15	-8.46	7.4	1.4e-13	0.03	1.00	0.00	FALSE
4	GTEx	Adipose Subcutaneous	PRICKLE4	0.10	0.09	lasso	8	0.08	9.2e-07	2.92	-5.4	5.9e-08	0.01	0.98	0.01	TRUE
5	GTEx	Adipose Subcutaneous	MED20	0.08	0.07	enet	9	0.05	4.7e-05	9.06	9.0	3.0e-19	0.01	0.96	0.01	FALSE
6	GTEx	Adipose Subcutaneous	FRS3	0.15	0.04	enet	22	0.04	5.9e-04	8.31	5.6	1.7e-08	0.01	0.20	0.56	TRUE
7	GTEx	Adipose Visceral Omentum	SUPT3H	0.27	0.10	lasso	7	0.06	3.4e-04	12.54	-14.6	4.1e-48	0.63	0.08	0.92	FALSE
8	GTEx	Artery Coronary	MED20	0.21	0.06	lasso	5	0.10	2.3e-04	3.83	6.2	4.6e-10	-0.05	0.06	0.52	FALSE
9	GTEx	Artery Tibial	PRICKLE4	0.11	0.09	lasso	3	0.08	1.3e-06	-3.04	-5.8	8.7e-09	-0.02	0.98	0.00	FALSE
10	GTEx	Artery Tibial	MED20	0.14	0.11	lasso	2	0.09	9.7e-08	9.03	9.0	1.8e-19	0.02	0.99	0.01	FALSE
11	GTEx	Artery Tibial	SUPT3H	0.13	0.01	enet	21	0.02	1.9e-02	-9.90	-13.5	1.8e-41	0.55	0.18	0.73	FALSE
12	GTEx	Brain Cortex	RP3-330M21.5	0.34	0.01	lasso	7	-0.01	5.3e-01	-6.36	6.1	1.3e-09	-0.02	0.05	0.07	FALSE
13	GTEx	Breast Mammary Tissue (Male)	RP3-475N16.1	0.08	-0.01	lasso	3	0.06	2.1e-02	-7.87	6.7	2.8e-11	0.03	0.03	0.22	FALSE
14	GTEx	Cells EBV-transformed lymphocytes	MED20	0.25	0.01	lasso	5	0.07	3.0e-03	-8.36	7.6	2.3e-14	0.02	0.15	0.12	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	SUPT3H	0.20	0.08	lasso	6	0.10	3.0e-04	12.81	-12.5	9.0e-36	0.66	0.23	0.46	FALSE
16	GTEx	Cells Transformed fibroblasts	CUL7	0.18	0.18	lasso	7	0.18	4.0e-13	-6.47	6.7	2.2e-11	-0.04	1.00	0.00	FALSE
17	GTEx	Cells Transformed fibroblasts	MED20	0.11	0.05	lasso	4	0.08	9.4e-07	-7.34	7.4	9.9e-14	0.00	0.86	0.09	FALSE
18	GTEx	Cells Transformed fibroblasts	USP49	0.13	0.02	lasso	4	0.02	2.4e-02	-6.84	-5.8	4.9e-09	0.00	0.29	0.03	FALSE
19	GTEx	Cells Transformed fibroblasts	SUPT3H	0.15	0.10	lasso	4	0.13	8.8e-10	12.90	-8.4	4.3e-17	0.25	0.29	0.71	FALSE
20	GTEx	Colon Transverse	MED20	0.17	0.01	enet	10	0.06	6.0e-04	9.05	11.2	4.9e-29	0.03	0.17	0.62	TRUE
21	GTEx	Esophagus Gastroesophageal Junction	SUPT3H	0.27	0.01	lasso	3	0.00	2.7e-01	-12.55	-12.1	6.4e-34	0.83	0.03	0.75	FALSE
22	GTEx	Esophagus Mucosa	MED20	0.09	0.07	enet	10	0.02	2.7e-02	-8.46	8.6	1.0e-17	0.02	0.76	0.13	FALSE
23	GTEx	Esophagus Mucosa	SUPT3H	0.08	0.09	lasso	3	0.08	6.4e-06	12.54	-13.4	5.0e-41	0.55	0.11	0.88	FALSE
24	GTEx	Esophagus Muscularis	MED20	0.15	0.05	lasso	7	0.04	1.0e-03	-8.49	9.0	1.7e-19	0.00	0.45	0.50	FALSE
25	GTEx	Esophagus Muscularis	SUPT3H	0.10	0.03	enet	20	0.02	1.3e-02	-12.55	-13.3	2.4e-40	0.71	0.01	0.94	FALSE
26	GTEx	Heart Atrial Appendage	PRICKLE4	0.16	0.07	enet	19	0.10	4.6e-05	-3.15	-6.3	3.9e-10	-0.04	0.24	0.52	FALSE
27	GTEx	Heart Atrial Appendage	MED20	0.14	0.12	enet	11	0.09	5.9e-05	8.77	9.0	3.3e-19	0.02	0.84	0.09	FALSE
28	GTEx	Heart Left Ventricle	PRICKLE4	0.11	0.05	lasso	4	0.03	9.8e-03	8.71	-8.7	2.6e-18	-0.03	0.26	0.06	FALSE
29	GTEx	Heart Left Ventricle	MED20	0.22	0.19	enet	8	0.12	5.8e-07	9.05	9.0	3.2e-19	0.02	1.00	0.00	FALSE
30	GTEx	Liver	MED20	0.20	0.03	enet	54	0.08	3.4e-03	9.00	6.4	1.7e-10	0.02	0.17	0.19	FALSE
31	GTEx	Liver	CRIP3	0.46	-0.01	enet	27	0.01	2.1e-01	-1.17	-7.9	3.5e-15	0.03	0.05	0.07	TRUE
32	GTEx	Lung	BYSL	0.08	0.03	lasso	4	0.02	4.9e-03	11.72	-11.0	5.5e-28	-0.02	0.27	0.56	TRUE
33	GTEx	Lung	PRICKLE4	0.12	0.05	lasso	3	0.06	2.2e-05	8.71	-7.7	1.9e-14	-0.04	0.60	0.07	FALSE
34	GTEx	Lung	MED20	0.10	0.01	lasso	4	0.00	2.7e-01	-2.08	8.3	9.1e-17	0.00	0.06	0.32	FALSE
35	GTEx	Lung	USP49	0.09	0.08	lasso	2	0.05	6.2e-05	-6.84	-6.0	2.0e-09	0.00	0.84	0.01	TRUE
36	GTEx	Lung	SUPT3H	0.10	0.06	enet	21	0.03	1.3e-03	12.17	-12.4	4.9e-35	0.49	0.28	0.67	FALSE
37	GTEx	Muscle Skeletal	PRICKLE4	0.07	0.05	lasso	2	0.05	2.1e-05	-2.88	-5.4	7.6e-08	-0.02	0.81	0.02	TRUE
38	GTEx	Muscle Skeletal	MED20	0.16	0.15	lasso	4	0.16	6.7e-16	8.71	8.8	1.3e-18	0.03	1.00	0.00	FALSE
39	GTEx	Muscle Skeletal	KLHDC3	0.06	0.04	lasso	4	0.03	1.2e-03	5.41	5.5	4.9e-08	0.00	0.17	0.20	TRUE
40	GTEx	Nerve Tibial	MED20	0.13	0.11	enet	8	0.10	1.5e-07	8.77	8.8	9.7e-19	0.02	1.00	0.00	FALSE
41	GTEx	Nerve Tibial	SUPT3H	0.17	0.12	lasso	5	0.10	2.2e-07	12.17	-12.2	2.1e-34	0.51	0.21	0.79	FALSE
42	GTEx	Pancreas	SUPT3H	0.11	0.07	lasso	2	0.05	3.6e-03	13.21	-13.2	7.4e-40	0.53	0.07	0.82	FALSE
43	GTEx	Skin Sun Exposed Lower leg	GNMT	0.07	0.09	lasso	1	0.09	9.9e-08	5.12	5.1	3.0e-07	0.01	0.95	0.01	FALSE
44	GTEx	Skin Sun Exposed Lower leg	SUPT3H	0.07	0.03	lasso	5	0.04	4.2e-04	12.17	-11.9	1.5e-32	0.46	0.17	0.66	FALSE
45	GTEx	Small Intestine Terminal Ileum	CUL7	0.27	0.07	lasso	7	0.06	1.6e-02	-3.99	5.9	4.5e-09	-0.06	0.12	0.20	TRUE
46	GTEx	Spleen	MED20	0.44	0.13	enet	23	0.07	6.4e-03	9.03	7.6	3.9e-14	0.00	0.11	0.51	FALSE
47	GTEx	Spleen	SUPT3H	0.32	0.06	enet	12	0.11	9.5e-04	10.89	-11.8	3.1e-32	0.41	0.24	0.34	FALSE
48	GTEx	Spleen	LRRC73	0.38	0.01	lasso	8	0.00	2.8e-01	-7.23	-5.3	8.9e-08	0.00	0.06	0.06	FALSE
49	GTEx	Stomach	GNMT	0.64	0.00	lasso	13	0.00	5.0e-01	-6.47	-5.4	8.2e-08	-0.02	0.05	0.20	TRUE
50	GTEx	Stomach	CNPY3	0.17	0.18	lasso	2	0.17	1.7e-08	5.12	-5.2	2.7e-07	-0.01	0.91	0.01	FALSE
51	GTEx	Testis	MED20	0.13	0.03	lasso	6	0.00	2.0e-01	-6.86	7.8	7.6e-15	0.00	0.16	0.17	FALSE
52	GTEx	Thyroid	CUL7	0.25	0.12	lasso	8	0.17	1.0e-12	-3.79	5.5	3.7e-08	-0.06	1.00	0.00	TRUE
53	GTEx	Thyroid	MED20	0.05	0.05	lasso	2	0.02	8.1e-03	9.03	8.9	3.5e-19	0.02	0.50	0.36	FALSE
54	GTEx	Thyroid	FRS3	0.20	0.16	lasso	4	0.16	5.2e-12	8.31	7.4	1.4e-13	0.07	0.98	0.02	FALSE
55	GTEx	Thyroid	SUPT3H	0.29	0.07	lasso	8	0.07	7.3e-06	-10.85	-12.8	2.5e-37	0.52	0.79	0.15	TRUE
56	METSIM	Adipose	BYSL	0.05	0.00	blup	476	0.02	2.3e-04	8.71	-6.8	1.2e-11	-0.04	0.18	0.06	FALSE
57	METSIM	Adipose	MED20	0.13	0.11	enet	27	0.11	2.3e-16	8.86	9.1	1.1e-19	0.02	1.00	0.00	FALSE
58	METSIM	Adipose	SUPT3H	0.11	0.04	bslmm	657	0.06	2.7e-09	12.91	-12.5	8.0e-36	0.59	0.39	0.61	FALSE
59	NTR	Blood	KLHDC3	0.01	0.00	blup	368	0.01	3.6e-03	-5.86	8.2	2.6e-16	0.07	0.04	0.76	FALSE
60	NTR	Blood	SUPT3H	0.03	0.02	lasso	7	0.02	1.9e-07	-4.84	-6.7	2.8e-11	0.18	0.99	0.01	FALSE
61	NTR	Blood	ZNF318	0.04	0.03	lasso	8	0.02	1.3e-08	-7.54	-7.9	2.8e-15	-0.06	1.00	0.00	TRUE
62	ROSMAP	Brain Pre-frontal Cortex	PGC	0.13	0.06	blup	520	0.06	3.2e-08	8.31	-8.6	8.6e-18	0.00	0.97	0.03	FALSE
63	ROSMAP	Brain Pre-frontal Cortex	PPP2R5D	0.05	0.00	bslmm	366	0.03	1.1e-04	-6.70	7.3	3.3e-13	-0.02	0.19	0.13	FALSE
64	ROSMAP	Brain Pre-frontal Cortex	MED20	0.10	0.10	enet	21	0.09	6.0e-12	9.03	10.5	1.0e-25	0.01	1.00	0.00	FALSE
65	ROSMAP	Brain Pre-frontal Cortex	KLC4	0.06	0.00	blup	362	0.01	5.6e-03	-7.90	10.0	1.6e-23	0.02	0.25	0.32	TRUE
66	YFS	Blood	BYSL	0.07	0.06	lasso	7	0.09	2.8e-28	9.03	-7.9	3.9e-15	-0.02	1.00	0.00	FALSE
67	YFS	Blood	CCND3	0.02	0.01	enet	13	0.02	2.3e-06	9.97	-11.2	4.1e-29	-0.03	0.72	0.22	FALSE
68	YFS	Blood	MEA1	0.01	0.00	blup	351	0.01	4.4e-03	-0.43	6.0	2.3e-09	-0.03	0.11	0.10	FALSE
69	YFS	Blood	MED20	0.04	0.03	lasso	5	0.03	3.6e-11	8.71	8.8	2.1e-18	0.03	1.00	0.00	FALSE
70	YFS	Blood	MRPL2	0.15	0.07	bslmm	352	0.10	1.1e-31	-6.77	-6.4	1.4e-10	-0.04	1.00	0.00	FALSE
71	YFS	Blood	SUPT3H	0.06	0.09	lasso	13	0.12	2.2e-36	12.17	-8.5	1.5e-17	0.21	0.58	0.42	FALSE
72	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCND3	0.04	0.00	blup	99	0.01	1.8e-03	-6.89	7.6	3.4e-14	-0.01	0.02	0.10	FALSE
73	The Cancer Genome Atlas	Breast Invasive Carcinoma	SUPT3H	0.02	0.01	blup	191	0.01	3.0e-03	12.54	-11.5	1.0e-30	0.41	0.15	0.82	FALSE
74	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C6orf108	0.08	0.02	blup	38	0.06	4.7e-04	-5.56	5.2	2.2e-07	0.03	0.01	0.94	FALSE
75	The Cancer Genome Atlas	Colon Adenocarcinoma	MED20	0.05	0.00	blup	50	0.04	2.8e-03	8.71	11.0	5.9e-28	0.02	0.06	0.27	FALSE
76	The Cancer Genome Atlas	Colon Adenocarcinoma	SUPT3H	0.08	0.01	blup	191	0.05	1.0e-03	12.90	-16.2	5.1e-59	0.85	0.02	0.94	TRUE
77	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MED20	0.04	0.03	lasso	3	0.04	7.3e-05	-7.34	7.7	1.9e-14	0.00	0.57	0.02	FALSE
78	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SUPT3H	0.04	0.01	blup	191	0.02	6.5e-03	-0.52	-7.7	1.3e-14	0.06	0.17	0.75	FALSE
79	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCND3	0.09	0.04	enet	12	0.07	1.3e-08	-0.75	-5.2	1.7e-07	-0.03	0.95	0.02	FALSE
80	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPP2R5D	0.03	0.03	lasso	4	0.02	1.6e-03	5.12	6.3	2.5e-10	0.02	0.02	0.32	FALSE
81	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PRICKLE4	0.05	0.04	blup	42	0.04	2.3e-05	-2.91	-5.3	1.4e-07	-0.04	0.70	0.13	FALSE
82	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TFEB	0.04	0.00	blup	84	0.02	2.7e-03	3.83	-6.3	2.4e-10	0.02	0.01	0.03	TRUE
83	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TOMM6	0.04	0.01	enet	12	0.03	6.5e-04	-2.89	-7.1	1.5e-12	0.01	0.02	0.84	FALSE
84	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CCND3	0.11	0.02	blup	99	0.03	1.3e-02	-3.07	-6.1	8.1e-10	-0.05	0.03	0.07	FALSE
85	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CRIP3	0.08	0.08	blup	34	0.07	1.0e-04	-7.95	-7.9	2.9e-15	-0.04	0.00	0.99	FALSE
86	The Cancer Genome Atlas	Brain Lower Grade Glioma	MED20	0.09	0.08	enet	12	0.09	5.5e-10	9.03	10.5	5.3e-26	0.02	1.00	0.00	FALSE
87	The Cancer Genome Atlas	Brain Lower Grade Glioma	SUPT3H	0.07	0.05	enet	12	0.08	1.1e-09	-0.35	-7.7	1.6e-14	0.10	0.52	0.48	FALSE
88	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MED20	0.09	0.07	lasso	5	0.07	3.4e-04	-6.86	8.6	8.1e-18	0.01	0.17	0.55	FALSE
89	The Cancer Genome Atlas	Lung Adenocarcinoma	SUPT3H	0.03	0.03	lasso	2	0.02	8.9e-04	12.88	-12.2	1.9e-34	0.48	0.18	0.45	FALSE
90	The Cancer Genome Atlas	Lung Adenocarcinoma	ZNF318	0.05	0.06	lasso	3	0.05	1.1e-06	-6.75	6.9	4.8e-12	0.07	0.80	0.10	FALSE
91	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PRICKLE4	0.03	0.01	blup	43	0.02	1.6e-03	-2.91	-7.7	1.2e-14	-0.02	0.04	0.89	FALSE
92	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf108	0.05	0.03	lasso	4	0.04	8.5e-04	-4.74	5.6	1.7e-08	0.01	0.01	0.95	FALSE
93	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SUPT3H	0.12	0.08	blup	191	0.09	2.8e-04	13.67	-14.2	6.3e-46	0.62	0.14	0.80	FALSE
94	The Cancer Genome Atlas	Prostate Adenocarcinoma	GNMT	0.10	0.07	enet	6	0.07	1.1e-07	-8.58	-8.4	3.3e-17	-0.03	0.06	0.94	TRUE
95	The Cancer Genome Atlas	Prostate Adenocarcinoma	MED20	0.04	0.06	enet	6	0.05	2.6e-06	8.71	9.9	6.0e-23	0.02	0.91	0.02	TRUE
96	The Cancer Genome Atlas	Prostate Adenocarcinoma	PRICKLE4	0.03	0.00	blup	43	0.01	5.5e-02	8.77	-5.9	4.0e-09	-0.02	0.00	0.76	FALSE
97	The Cancer Genome Atlas	Rectum Adenocarcinoma	C6orf108	0.47	0.06	enet	24	0.13	5.0e-04	-7.87	6.3	2.4e-10	0.01	0.00	0.66	FALSE
98	The Cancer Genome Atlas	Soft Tissue Sarcoma	ZNF318	0.04	0.02	blup	48	0.04	2.2e-03	-7.94	-7.5	8.9e-14	-0.05	0.01	0.80	FALSE
99	The Cancer Genome Atlas	Stomach Adenocarcinoma	MED20	0.03	0.05	lasso	2	0.04	1.2e-03	-7.34	7.7	1.2e-14	0.00	0.11	0.06	FALSE
100	The Cancer Genome Atlas	Stomach Adenocarcinoma	SUPT3H	0.05	0.01	blup	191	0.00	1.4e-01	-0.34	-5.7	1.0e-08	-0.09	0.12	0.08	FALSE
101	The Cancer Genome Atlas	Thyroid Carcinoma	BYSL	0.05	0.06	enet	7	0.06	4.3e-06	9.03	-8.9	6.9e-19	-0.01	0.82	0.09	FALSE
102	The Cancer Genome Atlas	Thyroid Carcinoma	PRICKLE4	0.04	0.03	lasso	3	0.04	1.1e-04	7.15	-7.4	1.0e-13	-0.08	0.07	0.85	FALSE
103	The Cancer Genome Atlas	Thyroid Carcinoma	SUPT3H	0.06	0.04	lasso	4	0.05	2.1e-05	12.88	-14.8	8.7e-50	0.65	0.18	0.76	FALSE