TWAS hub - TOMM6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.0359	0.0198	0.00095	0.007	0.023	0.025	NA	0.009	4.8e-02	0.0011	0.00065	NA	0.0260
2	TCGA	Prostate Adenocarcinoma	0.0407	0.0203	0.00017	0.037	0.021	0.012	NA	0.018	7.8e-05	0.0024	0.01700	NA	0.0043

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood Red Count	81.8	790.6	1239.0	18.5	35.2
Ever had bowel cancer screening	14.7	17.2	22.1	3.5	4.7
Supplements: Vitamin C	11.9	14.0	15.6	3.5	4.0
Mineral and other dietary supplements	11.4	15.3	16.7	-3.7	-4.1
Age when periods started (menarche)	7.9	19.0	20.2	-4.2	-4.5
Medication: Omeprazole (e.g. Zanprol)	7.9	9.6	11.5	2.8	3.4
Relative age of first facial hair	7.5	15.3	16.2	-3.8	-4.0
Vitamin and mineral supplements	7.2	9.8	13.5	-2.5	-3.7
Supplements: Zinc	6.6	7.2	8.5	2.9	2.4
Illnesses of father: Heart disease	6.6	9.1	10.6	2.8	3.3
Chronotype (morning person)	6.2	14.2	24.0	-2.1	-4.9
Other serious medical condition/disability diagnosed by doctor	6.2	8.1	10.6	2.4	3.3
Average weekly beer plus cider intake	6.2	9.0	13.8	-2.1	-3.7
Osteoporosis (self-reported)	5.8	7.2	7.3	2.6	2.7
Qualifications: O levels/GCSEs or equivalent	5.5	8.8	12.9	2.2	3.6
Illnesses of father: High blood pressure	5.5	6.8	8.1	2.3	2.9
Illnesses of father: None of the above (group 1)	5.3	6.5	7.9	-2.3	-2.8
Illnesses of siblings	5.2	7.3	10.4	-2.0	-3.2
Pulse rate, automated reading	5.0	16.0	20.2	4.5	3.5
Long-standing illness, disability or infirmity	4.9	7.5	7.7	2.8	2.7
Stomach or abdominal pain in last month	4.7	5.9	9.3	1.6	3.0
Number of live births	4.7	6.7	11.0	-1.5	-3.3
Medication: Omeprazole	4.7	5.6	6.9	2.1	2.6
Alcohol usually taken with meals	4.6	7.5	10.8	2.0	3.3
Ever taken oral contraceptive pill	4.6	5.2	9.5	-0.9	-3.1
Mouth/teeth dental problems: Dentures	4.2	7.0	12.3	-1.3	-3.5
Migraine (self-reported)	4.1	5.1	5.4	2.2	2.3
Supplements: Glucosamine	4.0	5.2	6.9	1.9	2.6
Supplements: Fish oil (including cod liver oil)	4.0	5.2	5.3	2.3	2.3
Lupus	3.9	5.9	8.0	1.9	2.8
Supplements: Calcium	3.9	4.3	5.8	1.7	2.4
Average weekly red wine intake	3.8	5.6	7.5	1.9	2.7
Relative age voice broke	3.7	5.7	6.5	-2.5	-2.2
HDL Cholesterol	3.6	6.0	6.1	2.4	2.5
Depression (self-reported)	3.5	4.2	5.0	2.2	1.9
Pack years adult smoking proportion	3.4	5.1	6.8	-1.9	-2.6
Alcohol drinker status: Never	3.2	3.8	5.0	1.6	2.2
Smoking Status	3.1	7.3	8.9	-2.4	-3.0
Taking other prescription medications	3.1	4.9	7.1	2.7	1.6
Multivitamins +/- minerals	3.1	3.9	6.7	1.1	2.6
Had menopause	3.1	3.8	5.6	1.4	2.4
Exposure to tobacco smoke outside home	3.1	4.2	6.7	1.3	2.6
Friendships satisfaction	3.1	3.9	4.6	-1.8	-2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.1	6.6	6.7	2.6	2.5
Pulse rate	3.0	5.1	5.3	2.2	2.3
Forced expiratory volume in 1-second (FEV1), predicted	2.9	6.0	7.2	-2.7	-2.2
Alzheimer’s Disease (in mother)	2.8	3.3	3.4	1.8	1.8
Reaction Time	2.8	5.3	5.6	-2.2	-2.4
Current tobacco smoking	2.7	4.4	4.5	-2.1	-2.1
Leg predicted mass (right)	2.7	14.3	23.8	-4.9	-2.2
Allergy or Eczema	2.6	6.8	10.4	3.2	1.8
Leg fat-free mass (right)	2.6	14.0	23.3	-4.8	-2.2
Frequency of tiredness / lethargy in last 2 weeks	2.5	4.1	4.7	2.2	1.9
Wears glasses or contact lenses	2.5	2.9	4.3	1.2	2.1
Lung FVC	2.4	12.0	13.0	3.3	3.6
Frequency of depressed mood in last 2 weeks	2.4	3.4	5.6	1.1	2.4
Leg predicted mass (left)	2.4	12.8	21.3	-4.6	-2.1
Loud music exposure frequency	2.4	2.6	3.9	-1.2	-2.0
Mean time to correctly identify matches	2.4	4.5	5.1	-2.0	-2.3
Handedness (chirality/laterality): Left-handed	2.4	2.9	3.7	1.9	1.4
Qualifications: nursing, teaching	2.4	3.7	5.1	1.6	2.2
Medication: Gliclazide	2.4	2.8	5.0	-0.7	-2.2
Pain type(s) experienced in last month: Hip pain	2.4	3.0	5.5	0.7	2.4
Leg fat-free mass (left)	2.3	12.3	20.6	-4.5	-2.0
Hayfever, allergic rhinitis or eczema	2.3	5.0	7.7	2.8	1.5
Qualifications: None of the above	2.3	5.0	6.8	-1.8	-2.6
Hip circumference	2.3	10.0	17.1	-4.1	-1.7
Osteoarthritis (self-reported)	2.3	3.0	3.5	1.6	1.9
Schizophrenia vs Biploar Disorder	2.2	2.8	4.4	-1.2	-2.1
Number of treatments/medications taken	2.2	4.0	7.1	2.7	1.0
High blood pressure (siblings)	2.2	3.2	4.4	1.4	2.1
Chest pain or discomfort	2.2	3.2	4.5	1.4	2.1
Waist Hip Ratio (WHR)	2.1	9.6	12.0	2.7	3.5
Smoking status: Current	2.1	3.3	3.3	-1.8	-1.8
Basal metabolic rate	2.1	11.8	20.5	-4.5	-1.7
Ever unenthusiastic/disinterested for a whole week	2.0	2.5	3.7	-1.1	-1.9
Diabetes (self-reported)	2.0	3.1	5.8	-0.6	-2.4
Qualifications: A levels/AS levels or equivalent	2.0	4.4	7.4	1.2	2.7
Pulse wave reflection index	2.0	2.5	4.0	-1.0	-2.0
Height	1.9	36.2	50.0	-7.1	-4.7
Sitting height	1.9	13.7	18.8	-4.3	-2.9
Financial difficulties in last 2 years	1.9	2.5	2.9	1.7	1.5
Weight	1.9	9.3	16.2	-4.0	-1.5
Whole body fat-free mass	1.9	10.8	19.4	-4.4	-1.5
Eye problems/disorders: Cataract	1.9	2.2	2.8	1.3	1.7
Whole body water mass	1.9	11.0	19.7	-4.4	-1.5
Pack years of smoking	1.9	2.8	3.4	-1.5	-1.8
Primary Biliary Cirrhosis	1.8	2.6	2.7	-1.7	-1.5
Lung cancer (father)	1.8	2.1	2.4	-1.3	-1.5
Standing height	1.8	18.2	25.9	-5.1	-3.2
Commuting to job workplace: Walk	1.8	2.0	2.5	1.2	1.6
Number of self-reported non-cancer illnesses	1.8	3.2	4.6	2.1	1.3
Tinnitus: Yes, now most or all of the time	1.8	2.1	2.3	1.5	1.4
Body Mass Index (BMI) (2010)	1.7	2.4	4.0	-2.0	-0.9
Hayfever/allergic rhinitis (self-reported)	1.7	2.3	2.3	1.5	1.5
Tense / ‘highly strung’	1.7	2.9	2.9	1.7	1.7
Comparative height size at age 10	1.7	9.2	13.2	-3.6	-2.3
Ever smoked	1.7	3.0	4.4	-1.2	-2.1
Worry (Nagel 2018)	1.6	3.3	3.4	1.8	1.8
Fasting Glucose	1.6	1.9	2.8	1.7	1.0
Maternal smoking around birth	1.6	2.4	3.6	-1.0	-1.9
Breastfed as a baby	1.6	2.0	2.3	1.3	1.5
Arm fat-free mass (right)	1.6	8.1	15.1	-3.9	-1.0
Arm predicted mass (right)	1.6	8.0	15.1	-3.9	-1.0
Diabetes diagnosed by doctor	1.6	2.7	4.8	-0.8	-2.2
Arm fat-free mass (left)	1.6	8.3	16.1	-4.0	-0.7
Depression (Nagel 2018)	1.5	2.2	4.1	0.6	2.0
Schizophrenia (2018)	1.5	3.1	3.3	-1.8	-1.7
Type 2 Diabetes (T2D) (2018)	1.5	2.7	5.0	-0.7	-2.2
Trunk fat mass	1.5	6.6	9.7	-3.1	-1.9
Trunk fat-free mass	1.5	8.4	15.6	-4.0	-1.1
Trunk predicted mass	1.5	8.5	15.8	-4.0	-1.1
Illnesses of siblings: Diabetes	1.5	1.9	3.4	0.5	1.9
Arm predicted mass (left)	1.5	7.4	14.5	-3.8	-0.6
Ulcerative Colitis (UC)	1.4	2.6	4.4	0.9	2.1
Schizophrenia (2014)	1.4	3.0	4.0	-2.0	-1.4
Diabetes (father)	1.4	1.7	2.0	-1.4	-1.2
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	2.2	-1.1	-1.5
Past tobacco smoking	1.4	2.7	4.4	1.0	2.1
Medication: Ramipril	1.4	1.7	1.8	-1.3	-1.4
Smoking status: Previous	1.4	2.1	3.8	-0.7	-2.0
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	2.8	-0.4	-1.7
Heart disease (siblings)	1.4	1.7	2.3	1.5	1.0
Major Depression (MDD)	1.3	1.6	2.4	0.8	1.6
Medication: Co-codamol	1.3	1.5	1.7	1.3	1.1
Time employed in main current job	1.3	1.5	1.8	1.1	1.3
Arm fat mass (right)	1.3	5.3	9.2	-3.0	-1.1
Eye problems/disorders: None of the above	1.3	1.5	1.8	-1.1	-1.4
Ever had prostate specific antigen (PSA) test	1.3	1.5	3.0	-0.3	-1.7
Alzheimer’s Disease (in father)	1.2	1.3	2.0	-0.8	-1.4
Neuroticism (2016)	1.2	1.8	3.0	-1.7	-0.8
Neuroticism	1.2	2.8	3.8	1.3	2.0
Fed-up feelings	1.2	2.1	3.4	0.9	1.8
Falls in the last year	1.2	1.7	2.3	1.0	1.5
Noisy workplace	1.2	1.5	2.6	1.6	0.6
Illnesses of mother	1.2	1.5	3.0	-1.7	-0.2
Peak expiratory flow (PEF)	1.2	2.7	3.9	2.0	1.2
Neck or shoulder pain in last month	1.2	1.7	2.8	0.8	1.7
Back pain experienced in last month	1.2	1.7	2.1	1.1	1.5
Arm fat mass (left)	1.2	4.8	8.3	-2.9	-1.2
Medication: Bendroflumethiazide	1.2	1.8	2.0	-1.4	-1.3
Alcohol drinker status: Previous	1.2	1.3	1.6	1.3	1.0
Alzheimer’s Disease (including proxy)	1.1	1.6	1.9	1.4	1.1
Trunk fat percentage	1.1	4.5	5.5	-2.3	-1.9
Allergy	1.1	2.4	4.2	-2.0	-0.8
Average weekly champagne plus white wine intake	1.1	1.5	2.5	0.7	1.6
Medication: Metformin	1.0	1.4	2.4	-0.5	-1.6
Mouth/teeth dental problems	1.0	1.5	3.1	0.1	1.8
Medication for pain relief, constipation, heartburn	1.0	1.7	3.0	-1.7	-0.6
Alcohol intake frequency.	1.0	2.3	2.8	1.7	1.4
Unable to work because of sickness or disability	1.0	1.4	2.7	0.2	-1.6
Neuroticism score	0.9	1.8	2.4	1.1	1.6
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	1.9	0.2	1.4
Comparative body size at age 10	0.9	2.6	4.8	-2.2	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	2.1	0.5	1.5
Shortness of breath walking on level ground	0.9	1.0	1.6	-1.3	-0.7
Whole body fat mass	0.9	4.0	6.9	-2.6	-1.0
Irritability	0.9	1.6	1.6	1.2	1.3
Bipolar Disorder or Schizophrenia	0.8	2.0	2.0	-1.4	-1.4
Bipolar Disorder (2011)	0.8	0.8	1.6	-1.3	-0.0
Triglycerides	0.8	1.3	1.7	-1.3	-0.9
Diabetes (mother)	0.8	1.0	1.9	0.1	-1.4
Impedance of leg (right)	0.8	4.0	7.9	2.8	0.5
Hair/balding pattern: Pattern 3	0.8	1.2	1.9	0.7	1.4
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	1.1	0.9	1.1
Gout (self-reported)	0.8	1.1	1.9	0.5	1.4
Medication: Ventolin 100micrograms inhaler	0.8	1.0	1.1	0.9	1.1
Birth weight	0.8	1.8	3.4	-1.8	-0.4
Wheeze or whistling in the chest in last year	0.8	1.4	2.2	-1.5	-0.8
Number of operations (self-reported)	0.8	1.2	2.4	-0.3	-1.5
Mean Putamen Volume	0.7	0.8	0.9	1.0	0.8
Ulcerative Colitis	0.7	0.9	1.9	-0.0	1.4
High blood pressure (mother)	0.7	0.9	1.8	1.3	-0.3
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.6	-1.3	-0.4
Arm fat percentage (left)	0.7	2.6	3.3	-1.8	-1.4
Mood swings	0.7	1.2	2.3	0.4	1.5
Hearing aid user	0.7	0.8	1.0	1.0	0.8
Fractured/broken bones in last 5 years	0.7	0.9	1.3	0.7	1.2
Age started oral contraceptive pill	0.7	0.9	0.9	0.9	1.0
Neuroticism (Nagel 2018)	0.6	1.4	2.2	0.7	1.5
Systolic blood pressure, automated reading	0.6	1.6	2.4	0.9	1.5
Impedance of leg (left)	0.6	3.0	6.0	2.4	0.4
Impedance of arm (left)	0.6	2.7	5.3	0.3	-2.3
Birth weight of first child	0.6	1.0	1.5	-1.2	-0.7
Medication: Blood pressure	0.6	1.0	1.2	1.1	-0.9
Leg pain on walking	0.6	0.7	1.0	0.6	-1.0
Breast Cancer	0.5	1.2	1.9	1.4	0.7
Respiratory disease	0.5	1.1	1.5	0.8	1.2
Ever had hysterectomy (womb removed)	0.5	0.6	1.0	-1.0	-0.5
Angina	0.5	0.6	0.8	0.9	-0.7
Townsend deprivation index at recruitment	0.5	0.7	1.4	1.2	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.2	1.5	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.1	1.0	0.7
Arm fat percentage (right)	0.5	2.2	3.4	-1.8	-1.0
Medication: Lansoprazole	0.5	0.6	0.8	0.9	0.6
Exposure to tobacco smoke at home	0.5	0.6	1.1	0.4	-1.0
Medication: Paracetamol	0.5	0.8	1.2	1.1	0.7
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.1	-1.0	0.7
Angina (self-reported)	0.5	0.7	0.7	0.8	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.0	0.5	1.0
Miserableness	0.5	0.9	1.3	-1.1	-0.7
Financial situation satisfaction	0.5	0.6	0.8	-0.9	-0.7
Leg fat mass (left)	0.5	1.9	3.8	-1.9	-0.3
Depressed Affect (Nagel 2018)	0.4	0.8	1.6	-0.2	1.3
Irritable Bowel Disease (IBD)	0.4	1.1	2.0	0.4	1.4
Verbal and Numeric Reasoning (VNR)	0.4	1.1	1.8	-1.3	-0.6
HbA1C	0.4	0.5	0.9	-1.0	-0.0
LDL Cholesterol	0.4	0.6	1.2	0.0	-1.1
Rheumatoid Arthritis	0.4	0.6	1.0	0.5	1.0
Type 2 Diabetes (T2D) (2012)	0.4	0.5	0.6	0.6	0.8
Sensitivity / hurt feelings	0.4	0.7	1.3	0.3	1.1
Medication: Atenolol	0.4	0.5	0.9	1.0	-0.1
Waist circumference	0.4	1.6	3.1	-1.8	0.3
Heart attack	0.4	0.5	0.6	0.8	-0.6
Pain all over the body in last month	0.4	0.4	0.5	-0.5	-0.7
Impedance of arm (right)	0.4	1.7	3.2	0.4	-1.8
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	2.3	1.5	0.4
Length of working week for main job	0.4	0.5	0.9	-1.0	-0.0
Blood clot in the leg (DVT)	0.4	0.5	1.0	1.0	0.2
Body fat percentage	0.4	1.7	2.5	-1.6	-1.0
Number of full brothers	0.4	0.5	0.6	0.8	0.6
Medication: Ibuprofen	0.4	0.5	0.8	0.3	0.9
Medication: Allopurinol	0.4	0.5	1.0	-1.0	0.2
Medication: Aspirin	0.4	0.5	1.0	1.0	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.1	1.0	0.6
Breast cancer (self-reported)	0.4	0.5	0.6	0.7	0.8
Ever depressed for a whole week	0.4	0.5	0.8	-0.3	-0.9
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.8	0.9	-0.5
Blood White Count	0.3	1.9	3.4	-0.6	-1.9
BMI	0.3	1.5	3.0	-1.7	0.1
Hand grip strength (left)	0.3	0.8	1.7	-0.0	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.6	0.5	0.8
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.4	0.5	-0.7
Body mass index (BMI)	0.3	1.5	2.9	-1.7	0.1
Number of incorrect matches in round	0.3	0.5	0.9	-0.4	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	1.5	1.2	-0.2
Medication: Simvastatin	0.3	0.4	0.4	0.7	-0.6
Worrier / anxious feelings	0.3	0.6	0.9	0.5	0.9
Prospective memory result	0.3	0.4	0.7	-0.3	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	1.3	1.1	0.9
Pulse wave Arterial Stiffness index	0.3	0.3	0.7	-0.0	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.7	0.8	0.4
Glaucoma (self-reported)	0.3	0.4	0.4	0.7	0.6
Medication: Amlodipine	0.3	0.5	0.8	0.9	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.6	-0.8	-0.3
Health satisfaction	0.3	0.4	0.5	-0.5	-0.7
Leg fat mass (right)	0.3	1.3	2.6	-1.6	0.0
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.7	-0.8	0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.7	0.0	-0.8
Loneliness, isolation	0.3	0.5	0.9	0.1	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.6	0.8	0.2
Mother’s age at death	0.3	0.4	0.4	-0.6	-0.6
Commuting to job workplace: Public transport	0.3	0.3	0.4	-0.5	-0.7
Medication: Atorvastatin	0.3	0.4	0.7	0.0	-0.8
Diastolic blood pressure, automated reading	0.3	1.0	1.8	0.4	1.3
Impedance of whole body	0.3	1.7	1.9	1.4	-1.2
Intelligence (Savage-Jansen 2018)	0.2	0.6	0.8	-0.9	-0.5
Coronary Artery Disease (CAD)	0.2	0.2	0.4	0.2	-0.6
Crohns Disease (2012)	0.2	0.3	0.5	-0.7	0.0
Systolic Blood Pressure	0.2	0.9	1.5	1.2	0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.2	0.4	0.4
Medication for hormone replacement therapy	0.2	0.2	0.3	0.3	-0.6
Severe depression (siblings)	0.2	0.2	0.4	-0.3	0.6
Hand grip strength (right)	0.2	0.5	0.9	-0.9	0.2
Serious illness, injury or assault to yourself	0.2	0.2	0.3	-0.4	-0.5
Nervous feelings	0.2	0.3	0.4	0.6	0.6
Father’s age at death	0.2	0.3	0.6	0.3	0.8
Medication: Cholesterol lowering	0.2	0.4	0.7	0.3	-0.8
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.5	0.7	-0.3
Suffer from ‘nerves’	0.2	0.3	0.7	0.1	0.8
Overall health rating	0.2	0.5	0.6	-0.8	-0.7
Had major operations	0.2	0.3	0.4	0.6	0.3
Family relationship satisfaction	0.2	0.2	0.3	-0.5	0.3
Guilty feelings	0.2	0.2	0.5	-0.7	-0.1
Risk taking	0.2	0.3	0.5	-0.4	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.5	0.7	-0.3
Blood Eosinophil Count	0.1	0.5	0.6	0.6	0.8
Heel T-Score	0.1	1.2	2.0	1.4	-0.5
Cardiovascular Disease	0.1	0.3	0.3	0.6	-0.6
Hypothyroidism (self reported)	0.1	0.2	0.2	-0.5	0.5
Hair Pigment	0.1	3.4	5.6	-2.4	-1.1
Average weekly spirits intake	0.1	0.1	0.1	-0.3	-0.3
Qualifications: CSEs or equivalent	0.1	0.1	0.3	0.0	-0.5
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	0.4	-0.2
Hearing difficulty/problems with background noise	0.1	0.2	0.4	0.6	-0.2
Hair/balding pattern: Pattern 2	0.1	0.1	0.2	-0.0	-0.4
Had other major operations	0.1	0.1	0.2	-0.1	-0.5
Forced vital capacity (FVC)	0.1	0.2	0.4	0.7	-0.2
Fluid intelligence score	0.1	0.1	0.2	-0.5	-0.2
Hair/balding pattern: Pattern 4	0.1	0.2	0.3	-0.6	-0.1
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.3	-0.1	0.5
Forced vital capacity (FVC), Best measure	0.1	0.3	0.4	0.6	0.5
Leg fat percentage (right)	0.1	0.3	0.5	0.1	0.7
Age at first live birth	0.1	0.3	0.5	0.1	0.7
Pulse wave peak to peak time	0.1	0.2	0.2	-0.3	0.5
Qualifications: College or University degree	0.1	0.3	0.5	-0.7	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	0.1	-0.5
Number of full sisters	0.1	0.2	0.2	-0.3	0.5
Age at last live birth	0.1	0.1	0.1	-0.2	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	0.5	0.2
Knee pain experienced in last month	0.1	0.1	0.2	0.4	-0.0
Hypertension (Self-reported)	0.1	0.2	0.3	-0.0	-0.6
Asthma (self-reported)	0.1	0.2	0.2	0.3	0.5
Medication: Aspirin	0.1	0.1	0.1	0.3	-0.4
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	0.3	0.3
Medication: Blood pressure	0.1	0.1	0.1	0.3	0.4
Commuting to job workplace: Cycle	0.1	0.1	0.2	-0.5	-0.1
Myopia	0.1	0.1	0.2	-0.4	0.3
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.3	0.2	0.5
Cholesterol lowering medication	0.1	0.1	0.1	0.4	-0.2
Pain experienced in last month	0.1	0.2	0.4	0.1	-0.6
Basal cell carcinoma (self-reported)	0.1	0.1	0.1	-0.3	-0.1
Bipolar Disorder (2018)	0.0	0.0	0.0	-0.1	-0.0
Crohns Disease (2017)	0.0	0.1	0.1	-0.4	-0.2
Ovarian Cancer	0.0	0.0	0.1	-0.3	-0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.0	0.0	0.0	-0.0
Blood Platelet Count	0.0	0.6	1.1	1.1	-0.0
Lung FEV1/FVC ratio	0.0	0.0	0.0	0.2	0.1
Tanning	0.0	0.3	0.5	0.7	-0.2
Hearing difficulty/problems: Yes	0.0	0.0	0.0	0.1	0.1
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.0	0.1	0.2
Average weekly fortified wine intake	0.0	0.1	0.1	-0.3	0.1
High blood pressure	0.0	0.1	0.3	-0.1	-0.5
Medication: Levothyroxine sodium	0.0	0.0	0.0	0.1	0.1
Chronic bronchitis/emphysema (father)	0.0	0.0	0.0	-0.1	-0.1
Alcohol intake versus 10 years previously	0.0	0.0	0.1	0.0	-0.3
Happiness	0.0	0.0	0.0	-0.2	-0.2
Asthma	0.0	0.1	0.1	0.2	0.4
Ever highly irritable/argumentative for 2 days	0.0	0.1	0.1	-0.2	-0.3
Headache pain in last month	0.0	0.0	0.1	-0.3	0.1
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.1	-0.4	0.2
Worry too long after embarrassment	0.0	0.0	0.1	0.3	0.1
Number of children fathered	0.0	0.0	0.1	-0.3	-0.1
Emphysema/chronic bronchitis	0.0	0.0	0.0	-0.1	0.0
Medication: Seretide 50 evohaler	0.0	0.0	0.0	0.1	0.1
Heart disease (mother)	0.0	0.0	0.0	0.0	0.2
Medication for cholesterol	0.0	0.0	0.0	0.1	0.2
High cholesterol (Self-reported)	0.0	0.0	0.1	0.2	-0.2
Medication: Paracetamol	0.0	0.0	0.0	0.2	0.1
Medication: Lisinopril	0.0	0.0	0.1	0.0	-0.3
Leg fat percentage (left)	0.0	0.1	0.2	-0.3	0.4

Hub : Genes

TOMM6

Models

Trait associations