Hub : Genes

TOMM6

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Kidney Renal Clear Cell Carcinoma 0.0359 0.0198 0.00095 0.007 0.023 0.025 NA 0.009 4.8e-02 0.0011 0.00065 NA 0.0260
2 TCGA Prostate Adenocarcinoma 0.0407 0.0203 0.00017 0.037 0.021 0.012 NA 0.018 7.8e-05 0.0024 0.01700 NA 0.0043

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.0 0.0 0.0 -0.1 -0.0
Bipolar Disorder or Schizophrenia 0.8 2.0 2.0 -1.4 -1.4
Depressed Affect (Nagel 2018) 0.4 0.8 1.6 -0.2 1.3
Depression (Nagel 2018) 1.5 2.2 4.1 0.6 2.0
Intelligence (Savage-Jansen 2018) 0.2 0.6 0.8 -0.9 -0.5
Neuroticism (Nagel 2018) 0.6 1.4 2.2 0.7 1.5
Schizophrenia (2018) 1.5 3.1 3.3 -1.8 -1.7
Schizophrenia vs Biploar Disorder 2.2 2.8 4.4 -1.2 -2.1
Worry (Nagel 2018) 1.6 3.3 3.4 1.8 1.8
Alzheimer’s Disease (in mother) 2.8 3.3 3.4 1.8 1.8
Alzheimer’s Disease (in father) 1.2 1.3 2.0 -0.8 -1.4
Alzheimer’s Disease (including proxy) 1.1 1.6 1.9 1.4 1.1
Crohns Disease (2017) 0.0 0.1 0.1 -0.4 -0.2
Irritable Bowel Disease (IBD) 0.4 1.1 2.0 0.4 1.4
Ulcerative Colitis (UC) 1.4 2.6 4.4 0.9 2.1
Major Depression (MDD) 1.3 1.6 2.4 0.8 1.6
Reaction Time 2.8 5.3 5.6 -2.2 -2.4
Verbal and Numeric Reasoning (VNR) 0.4 1.1 1.8 -1.3 -0.6
Breast Cancer 0.5 1.2 1.9 1.4 0.7
Ovarian Cancer 0.0 0.0 0.1 -0.3 -0.0
Prostate Cancer 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.0 0.0 0.0 0.0 -0.0
Bipolar Disorder (2011) 0.8 0.8 1.6 -1.3 -0.0
Body Mass Index (BMI) (2010) 1.7 2.4 4.0 -2.0 -0.9
Coronary Artery Disease (CAD) 0.2 0.2 0.4 0.2 -0.6
Crohns Disease (2012) 0.2 0.3 0.5 -0.7 0.0
Mean Putamen Volume 0.7 0.8 0.9 1.0 0.8
Fasting Glucose 1.6 1.9 2.8 1.7 1.0
HbA1C 0.4 0.5 0.9 -1.0 -0.0
HDL Cholesterol 3.6 6.0 6.1 2.4 2.5
LDL Cholesterol 0.4 0.6 1.2 0.0 -1.1
Lupus 3.9 5.9 8.0 1.9 2.8
Neuroticism (2016) 1.2 1.8 3.0 -1.7 -0.8
Primary Biliary Cirrhosis 1.8 2.6 2.7 -1.7 -1.5
Rheumatoid Arthritis 0.4 0.6 1.0 0.5 1.0
Schizophrenia (2014) 1.4 3.0 4.0 -2.0 -1.4
Triglycerides 0.8 1.3 1.7 -1.3 -0.9
Type 2 Diabetes (T2D) (2012) 0.4 0.5 0.6 0.6 0.8
Ulcerative Colitis 0.7 0.9 1.9 -0.0 1.4
Blood Eosinophil Count 0.1 0.5 0.6 0.6 0.8
Blood Platelet Count 0.0 0.6 1.1 1.1 -0.0
Blood Red Count 81.8 790.6 1239.0 18.5 35.2
Blood White Count 0.3 1.9 3.4 -0.6 -1.9
Heel T-Score 0.1 1.2 2.0 1.4 -0.5
BMI 0.3 1.5 3.0 -1.7 0.1
Height 1.9 36.2 50.0 -7.1 -4.7
Waist Hip Ratio (WHR) 2.1 9.6 12.0 2.7 3.5
Systolic Blood Pressure 0.2 0.9 1.5 1.2 0.5
Smoking Status 3.1 7.3 8.9 -2.4 -3.0
Allergy or Eczema 2.6 6.8 10.4 3.2 1.8
Cardiovascular Disease 0.1 0.3 0.3 0.6 -0.6
Hypothyroidism (self reported) 0.1 0.2 0.2 -0.5 0.5
Respiratory disease 0.5 1.1 1.5 0.8 1.2
Type 2 Diabetes (T2D) (2018) 1.5 2.7 5.0 -0.7 -2.2
Lung FEV1/FVC ratio 0.0 0.0 0.0 0.2 0.1
Lung FVC 2.4 12.0 13.0 3.3 3.6
Neuroticism 1.2 2.8 3.8 1.3 2.0
Chronotype (morning person) 6.2 14.2 24.0 -2.1 -4.9
Hair Pigment 0.1 3.4 5.6 -2.4 -1.1
Tanning 0.0 0.3 0.5 0.7 -0.2
Hand grip strength (left) 0.3 0.8 1.7 -0.0 1.3
Number of treatments/medications taken 2.2 4.0 7.1 2.7 1.0
Average weekly spirits intake 0.1 0.1 0.1 -0.3 -0.3
Sensitivity / hurt feelings 0.4 0.7 1.3 0.3 1.1
Frequency of depressed mood in last 2 weeks 2.4 3.4 5.6 1.1 2.4
Hearing difficulty/problems: Yes 0.0 0.0 0.0 0.1 0.1
Relative age of first facial hair 7.5 15.3 16.2 -3.8 -4.0
Other serious medical condition/disability diagnosed by doctor 6.2 8.1 10.6 2.4 3.3
Ever used hormone-replacement therapy (HRT) 0.0 0.0 0.0 0.1 0.2
Ever had hysterectomy (womb removed) 0.5 0.6 1.0 -1.0 -0.5
Systolic blood pressure, automated reading 0.6 1.6 2.4 0.9 1.5
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.2 0.4 0.4
Angina 0.5 0.6 0.8 0.9 -0.7
Medication for hormone replacement therapy 0.2 0.2 0.3 0.3 -0.6
Vitamin and mineral supplements 7.2 9.8 13.5 -2.5 -3.7
Supplements: Zinc 6.6 7.2 8.5 2.9 2.4
Medication: Co-codamol 1.3 1.5 1.7 1.3 1.1
Medication: Metformin 1.0 1.4 2.4 -0.5 -1.6
Diabetes (father) 1.4 1.7 2.0 -1.4 -1.2
Diabetes (mother) 0.8 1.0 1.9 0.1 -1.4
Severe depression (siblings) 0.2 0.2 0.4 -0.3 0.6
Pack years adult smoking proportion 3.4 5.1 6.8 -1.9 -2.6
Impedance of leg (right) 0.8 4.0 7.9 2.8 0.5
Leg fat-free mass (left) 2.3 12.3 20.6 -4.5 -2.0
Trunk fat percentage 1.1 4.5 5.5 -2.3 -1.9
Hand grip strength (right) 0.2 0.5 0.9 -0.9 0.2
Townsend deprivation index at recruitment 0.5 0.7 1.4 1.2 0.2
Current tobacco smoking 2.7 4.4 4.5 -2.1 -2.1
Average weekly fortified wine intake 0.0 0.1 0.1 -0.3 0.1
Maternal smoking around birth 1.6 2.4 3.6 -1.0 -1.9
Fed-up feelings 1.2 2.1 3.4 0.9 1.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 0.6 0.5 0.8
Relative age voice broke 3.7 5.7 6.5 -2.5 -2.2
Taking other prescription medications 3.1 4.9 7.1 2.7 1.6
Age when periods started (menarche) 7.9 19.0 20.2 -4.2 -4.5
Bilateral oophorectomy (both ovaries removed) 1.4 1.6 2.2 -1.1 -1.5
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.1 2.2 1.5 -0.2
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 0.4 0.5 -0.7
Qualifications: CSEs or equivalent 0.1 0.1 0.3 0.0 -0.5
Serious illness, injury or assault to yourself 0.2 0.2 0.3 -0.4 -0.5
High blood pressure 0.0 0.1 0.3 -0.1 -0.5
Hayfever, allergic rhinitis or eczema 2.3 5.0 7.7 2.8 1.5
Multivitamins +/- minerals 3.1 3.9 6.7 1.1 2.6
Stomach or abdominal pain in last month 4.7 5.9 9.3 1.6 3.0
Supplements: Glucosamine 4.0 5.2 6.9 1.9 2.6
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.2 0.4 -0.2
Medication: Atenolol 0.4 0.5 0.9 1.0 -0.1
Medication: Levothyroxine sodium 0.0 0.0 0.0 0.1 0.1
Sitting height 1.9 13.7 18.8 -4.3 -2.9
Chronic bronchitis/emphysema (father) 0.0 0.0 0.0 -0.1 -0.1
High blood pressure (mother) 0.7 0.9 1.8 1.3 -0.3
Body mass index (BMI) 0.3 1.5 2.9 -1.7 0.1
Impedance of leg (left) 0.6 3.0 6.0 2.4 0.4
Leg predicted mass (left) 2.4 12.8 21.3 -4.6 -2.1
Trunk fat mass 1.5 6.6 9.7 -3.1 -1.9
Waist circumference 0.4 1.6 3.1 -1.8 0.3
Number of incorrect matches in round 0.3 0.5 0.9 -0.4 1.0
Past tobacco smoking 1.4 2.7 4.4 1.0 2.1
Alcohol usually taken with meals 4.6 7.5 10.8 2.0 3.3
Nervous feelings 0.2 0.3 0.4 0.6 0.6
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 1.1 1.0 0.7
Hearing difficulty/problems with background noise 0.1 0.2 0.4 0.6 -0.2
Hair/balding pattern: Pattern 2 0.1 0.1 0.2 -0.0 -0.4
Had menopause 3.1 3.8 5.6 1.4 2.4
Had other major operations 0.1 0.1 0.2 -0.1 -0.5
Forced vital capacity (FVC) 0.1 0.2 0.4 0.7 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.8 1.5 1.2 -0.2
Ever unenthusiastic/disinterested for a whole week 2.0 2.5 3.7 -1.1 -1.9
Qualifications: None of the above 2.3 5.0 6.8 -1.8 -2.6
Financial difficulties in last 2 years 1.9 2.5 2.9 1.7 1.5
Mouth/teeth dental problems 1.0 1.5 3.1 0.1 1.8
Heart attack 0.4 0.5 0.6 0.8 -0.6
Allergy 1.1 2.4 4.2 -2.0 -0.8
Pain all over the body in last month 0.4 0.4 0.5 -0.5 -0.7
Diabetes (self-reported) 2.0 3.1 5.8 -0.6 -2.4
Hayfever/allergic rhinitis (self-reported) 1.7 2.3 2.3 1.5 1.5
Medication: Ramipril 1.4 1.7 1.8 -1.3 -1.4
Medication: Simvastatin 0.3 0.4 0.4 0.7 -0.6
Fluid intelligence score 0.1 0.1 0.2 -0.5 -0.2
Illnesses of siblings 5.2 7.3 10.4 -2.0 -3.2
Neuroticism score 0.9 1.8 2.4 1.1 1.6
Weight 1.9 9.3 16.2 -4.0 -1.5
Impedance of arm (right) 0.4 1.7 3.2 0.4 -1.8
Arm fat percentage (right) 0.5 2.2 3.4 -1.8 -1.0
Trunk fat-free mass 1.5 8.4 15.6 -4.0 -1.1
Hip circumference 2.3 10.0 17.1 -4.1 -1.7
Time employed in main current job 1.3 1.5 1.8 1.1 1.3
Alcohol intake versus 10 years previously 0.0 0.0 0.1 0.0 -0.3
Father’s age at death 0.2 0.3 0.6 0.3 0.8
Worrier / anxious feelings 0.3 0.6 0.9 0.5 0.9
Frequency of tiredness / lethargy in last 2 weeks 2.5 4.1 4.7 2.2 1.9
Falls in the last year 1.2 1.7 2.3 1.0 1.5
Hair/balding pattern: Pattern 3 0.8 1.2 1.9 0.7 1.4
Number of live births 4.7 6.7 11.0 -1.5 -3.3
Forced expiratory volume in 1-second (FEV1) 0.4 1.2 2.3 1.5 0.4
Pulse rate 3.0 5.1 5.3 2.2 2.3
Happiness 0.0 0.0 0.0 -0.2 -0.2
Noisy workplace 1.2 1.5 2.6 1.6 0.6
Qualifications: A levels/AS levels or equivalent 2.0 4.4 7.4 1.2 2.7
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.0 1.9 0.2 1.4
Mouth/teeth dental problems: Dentures 4.2 7.0 12.3 -1.3 -3.5
Asthma 0.0 0.1 0.1 0.2 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.8 1.0 1.1 0.9 1.1
Medication: Cholesterol lowering 0.2 0.4 0.7 0.3 -0.8
Depression (self-reported) 3.5 4.2 5.0 2.2 1.9
Medication: Lansoprazole 0.5 0.6 0.8 0.9 0.6
Prospective memory result 0.3 0.4 0.7 -0.3 -0.8
Lung cancer (father) 1.8 2.1 2.4 -1.3 -1.5
Illnesses of mother 1.2 1.5 3.0 -1.7 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 1.0 1.3 1.1 0.9
Pulse wave Arterial Stiffness index 0.3 0.3 0.7 -0.0 -0.8
Impedance of arm (left) 0.6 2.7 5.3 0.3 -2.3
Arm fat mass (right) 1.3 5.3 9.2 -3.0 -1.1
Trunk predicted mass 1.5 8.5 15.8 -4.0 -1.1
Standing height 1.8 18.2 25.9 -5.1 -3.2
Length of working week for main job 0.4 0.5 0.9 -1.0 -0.0
Exposure to tobacco smoke at home 0.5 0.6 1.1 0.4 -1.0
Breastfed as a baby 1.6 2.0 2.3 1.3 1.5
Tense / ‘highly strung’ 1.7 2.9 2.9 1.7 1.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 0.7 0.8 0.4
Hair/balding pattern: Pattern 4 0.1 0.2 0.3 -0.6 -0.1
Birth weight of first child 0.6 1.0 1.5 -1.2 -0.7
Peak expiratory flow (PEF) 1.2 2.7 3.9 2.0 1.2
Pulse wave reflection index 2.0 2.5 4.0 -1.0 -2.0
Ever highly irritable/argumentative for 2 days 0.0 0.1 0.1 -0.2 -0.3
Loud music exposure frequency 2.4 2.6 3.9 -1.2 -2.0
Qualifications: O levels/GCSEs or equivalent 5.5 8.8 12.9 2.2 3.6
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 0.5 0.7 -0.3
Blood clot in the leg (DVT) 0.4 0.5 1.0 1.0 0.2
Medication: Paracetamol 0.5 0.8 1.2 1.1 0.7
Headache pain in last month 0.0 0.0 0.1 -0.3 0.1
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 1.1 -1.0 0.7
Glaucoma (self-reported) 0.3 0.4 0.4 0.7 0.6
Gout (self-reported) 0.8 1.1 1.9 0.5 1.4
Hypothyroidism/myxoedema (self-reported) 0.0 0.1 0.1 -0.4 0.2
Medication: Amlodipine 0.3 0.5 0.8 0.9 0.3
Medication: Ventolin 100micrograms inhaler 0.8 1.0 1.1 0.9 1.1
Birth weight 0.8 1.8 3.4 -1.8 -0.4
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.3 -0.1 0.5
High blood pressure (siblings) 2.2 3.2 4.4 1.4 2.1
Forced vital capacity (FVC), Best measure 0.1 0.3 0.4 0.6 0.5
Body fat percentage 0.4 1.7 2.5 -1.6 -1.0
Leg fat percentage (right) 0.1 0.3 0.5 0.1 0.7
Arm fat-free mass (right) 1.6 8.1 15.1 -3.9 -1.0
Exposure to tobacco smoke outside home 3.1 4.2 6.7 1.3 2.6
Comparative body size at age 10 0.9 2.6 4.8 -2.2 0.6
Number of full brothers 0.4 0.5 0.6 0.8 0.6
Worry too long after embarrassment 0.0 0.0 0.1 0.3 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.9 1.2 2.1 0.5 1.5
Wheeze or whistling in the chest in last year 0.8 1.4 2.2 -1.5 -0.8
Number of children fathered 0.0 0.0 0.1 -0.3 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 0.6 -0.8 -0.3
Age at first live birth 0.1 0.3 0.5 0.1 0.7
Pulse wave peak to peak time 0.1 0.2 0.2 -0.3 0.5
Health satisfaction 0.3 0.4 0.5 -0.5 -0.7
Shortness of breath walking on level ground 0.9 1.0 1.6 -1.3 -0.7
Qualifications: College or University degree 0.1 0.3 0.5 -0.7 0.1
Eye problems/disorders: None of the above 1.3 1.5 1.8 -1.1 -1.4
Mouth/teeth dental problems: Loose teeth 0.7 0.9 1.6 -1.3 -0.4
Emphysema/chronic bronchitis 0.0 0.0 0.0 -0.1 0.0
Medication for pain relief, constipation, heartburn 1.0 1.7 3.0 -1.7 -0.6
Neck or shoulder pain in last month 1.2 1.7 2.8 0.8 1.7
Medication: Blood pressure 0.6 1.0 1.2 1.1 -0.9
Angina (self-reported) 0.5 0.7 0.7 0.8 -0.8
Migraine (self-reported) 4.1 5.1 5.4 2.2 2.3
Medication: Ibuprofen 0.4 0.5 0.8 0.3 0.9
Medication: Allopurinol 0.4 0.5 1.0 -1.0 0.2
Medication: Omeprazole 4.7 5.6 6.9 2.1 2.6
Medication: Seretide 50 evohaler 0.0 0.0 0.0 0.1 0.1
Mean time to correctly identify matches 2.4 4.5 5.1 -2.0 -2.3
Heart disease (mother) 0.0 0.0 0.0 0.0 0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.2 0.1 -0.5
Whole body fat mass 0.9 4.0 6.9 -2.6 -1.0
Leg fat mass (right) 0.3 1.3 2.6 -1.6 0.0
Arm predicted mass (right) 1.6 8.0 15.1 -3.9 -1.0
Pulse rate, automated reading 5.0 16.0 20.2 4.5 3.5
Alcohol intake frequency. 1.0 2.3 2.8 1.7 1.4
Comparative height size at age 10 1.7 9.2 13.2 -3.6 -2.3
Number of full sisters 0.1 0.2 0.2 -0.3 0.5
Suffer from ‘nerves’ 0.2 0.3 0.7 0.1 0.8
Overall health rating 0.2 0.5 0.6 -0.8 -0.7
Chest pain or discomfort 2.2 3.2 4.5 1.4 2.1
Had major operations 0.2 0.3 0.4 0.6 0.3
Age at last live birth 0.1 0.1 0.1 -0.2 -0.3
Family relationship satisfaction 0.2 0.2 0.3 -0.5 0.3
Leg pain on walking 0.6 0.7 1.0 0.6 -1.0
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 0.2 0.5 0.2
Commuting to job workplace: Car/motor vehicle 0.3 0.4 0.7 -0.8 0.1
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 0.7 0.0 -0.8
Medication: Aspirin 0.4 0.5 1.0 1.0 -0.1
Supplements: Vitamin C 11.9 14.0 15.6 3.5 4.0
Knee pain experienced in last month 0.1 0.1 0.2 0.4 -0.0
Hypertension (Self-reported) 0.1 0.2 0.3 -0.0 -0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 1.0 0.5 1.0
Illnesses of father: Heart disease 6.6 9.1 10.6 2.8 3.3
Illnesses of siblings: Diabetes 1.5 1.9 3.4 0.5 1.9
Smoking status: Previous 1.4 2.1 3.8 -0.7 -2.0
Forced expiratory volume in 1-second (FEV1), predicted 2.9 6.0 7.2 -2.7 -2.2
Whole body fat-free mass 1.9 10.8 19.4 -4.4 -1.5
Leg fat-free mass (right) 2.6 14.0 23.3 -4.8 -2.2
Arm fat percentage (left) 0.7 2.6 3.3 -1.8 -1.4
Average weekly red wine intake 3.8 5.6 7.5 1.9 2.7
Handedness (chirality/laterality): Left-handed 2.4 2.9 3.7 1.9 1.4
Mood swings 0.7 1.2 2.3 0.4 1.5
Loneliness, isolation 0.3 0.5 0.9 0.1 1.0
Long-standing illness, disability or infirmity 4.9 7.5 7.7 2.8 2.7
Ever had bowel cancer screening 14.7 17.2 22.1 3.5 4.7
Diabetes diagnosed by doctor 1.6 2.7 4.8 -0.8 -2.2
Ever had stillbirth, spontaneous miscarriage or termination 1.4 1.5 2.8 -0.4 -1.7
Friendships satisfaction 3.1 3.9 4.6 -1.8 -2.1
Qualifications: nursing, teaching 2.4 3.7 5.1 1.6 2.2
Commuting to job workplace: Walk 1.8 2.0 2.5 1.2 1.6
Eye problems/disorders: Cataract 1.9 2.2 2.8 1.3 1.7
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 1.1 1.0 0.6
Medication for cholesterol 0.0 0.0 0.0 0.1 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 0.6 0.8 0.2
Back pain experienced in last month 1.2 1.7 2.1 1.1 1.5
Mineral and other dietary supplements 11.4 15.3 16.7 -3.7 -4.1
Breast cancer (self-reported) 0.4 0.5 0.6 0.7 0.8
Asthma (self-reported) 0.1 0.2 0.2 0.3 0.5
Osteoporosis (self-reported) 5.8 7.2 7.3 2.6 2.7
Osteoarthritis (self-reported) 2.3 3.0 3.5 1.6 1.9
Medication: Aspirin 0.1 0.1 0.1 0.3 -0.4
Medication: Gliclazide 2.4 2.8 5.0 -0.7 -2.2
Illnesses of father: None of the above (group 1) 5.3 6.5 7.9 -2.3 -2.8
Smoking status: Current 2.1 3.3 3.3 -1.8 -1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.1 6.6 6.7 2.6 2.5
Whole body water mass 1.9 11.0 19.7 -4.4 -1.5
Leg predicted mass (right) 2.7 14.3 23.8 -4.9 -2.2
Arm fat mass (left) 1.2 4.8 8.3 -2.9 -1.2
Number of self-reported non-cancer illnesses 1.8 3.2 4.6 2.1 1.3
Average weekly champagne plus white wine intake 1.1 1.5 2.5 0.7 1.6
Miserableness 0.5 0.9 1.3 -1.1 -0.7
Guilty feelings 0.2 0.2 0.5 -0.7 -0.1
Wears glasses or contact lenses 2.5 2.9 4.3 1.2 2.1
Ever taken oral contraceptive pill 4.6 5.2 9.5 -0.9 -3.1
Hearing aid user 0.7 0.8 1.0 1.0 0.8
Mother’s age at death 0.3 0.4 0.4 -0.6 -0.6
Financial situation satisfaction 0.5 0.6 0.8 -0.9 -0.7
Tinnitus: Yes, now most or all of the time 1.8 2.1 2.3 1.5 1.4
Commuting to job workplace: Public transport 0.3 0.3 0.4 -0.5 -0.7
Eye problems/disorders: Glaucoma 0.1 0.1 0.1 0.3 0.3
Medication: Blood pressure 0.1 0.1 0.1 0.3 0.4
Pain type(s) experienced in last month: Hip pain 2.4 3.0 5.5 0.7 2.4
Supplements: Fish oil (including cod liver oil) 4.0 5.2 5.3 2.3 2.3
High cholesterol (Self-reported) 0.0 0.0 0.1 0.2 -0.2
Medication: Bendroflumethiazide 1.2 1.8 2.0 -1.4 -1.3
Medication: Paracetamol 0.0 0.0 0.0 0.2 0.1
Medication: Lisinopril 0.0 0.0 0.1 0.0 -0.3
Medication: Atorvastatin 0.3 0.4 0.7 0.0 -0.8
Illnesses of father: High blood pressure 5.5 6.8 8.1 2.3 2.9
Alcohol drinker status: Never 3.2 3.8 5.0 1.6 2.2
Ever smoked 1.7 3.0 4.4 -1.2 -2.1
Basal metabolic rate 2.1 11.8 20.5 -4.5 -1.7
Leg fat percentage (left) 0.0 0.1 0.2 -0.3 0.4
Arm fat-free mass (left) 1.6 8.3 16.1 -4.0 -0.7
Number of operations (self-reported) 0.8 1.2 2.4 -0.3 -1.5
Average weekly beer plus cider intake 6.2 9.0 13.8 -2.1 -3.7
Irritability 0.9 1.6 1.6 1.2 1.3
Risk taking 0.2 0.3 0.5 -0.4 -0.7
Ever had prostate specific antigen (PSA) test 1.3 1.5 3.0 -0.3 -1.7
Fractured/broken bones in last 5 years 0.7 0.9 1.3 0.7 1.2
Age started oral contraceptive pill 0.7 0.9 0.9 0.9 1.0
Diastolic blood pressure, automated reading 0.3 1.0 1.8 0.4 1.3
Ever depressed for a whole week 0.4 0.5 0.8 -0.3 -0.9
Unable to work because of sickness or disability 1.0 1.4 2.7 0.2 -1.6
Commuting to job workplace: Cycle 0.1 0.1 0.2 -0.5 -0.1
Myopia 0.1 0.1 0.2 -0.4 0.3
Vascular/heart problems diagnosed by doctor 0.1 0.2 0.3 0.2 0.5
Cholesterol lowering medication 0.1 0.1 0.1 0.4 -0.2
Medication: Omeprazole (e.g. Zanprol) 7.9 9.6 11.5 2.8 3.4
Pain experienced in last month 0.1 0.2 0.4 0.1 -0.6
Supplements: Calcium 3.9 4.3 5.8 1.7 2.4
Basal cell carcinoma (self-reported) 0.1 0.1 0.1 -0.3 -0.1
Heart attack/myocardial infarction (self-reported) 0.4 0.5 0.8 0.9 -0.5
Deep venous thrombosis (DVT) (self-reported) 0.2 0.3 0.5 0.7 -0.3
Heart disease (siblings) 1.4 1.7 2.3 1.5 1.0
Alcohol drinker status: Previous 1.2 1.3 1.6 1.3 1.0
Pack years of smoking 1.9 2.8 3.4 -1.5 -1.8
Impedance of whole body 0.3 1.7 1.9 1.4 -1.2
Leg fat mass (left) 0.5 1.9 3.8 -1.9 -0.3
Arm predicted mass (left) 1.5 7.4 14.5 -3.8 -0.6