TWAS hub - LRRC73

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Spleen	0.375	0.122	0.0098	0.010	NA	-0.004	NA	0.002	0.18	NA	0.42	NA	0.28
2	GTEx	Testis	0.183	0.079	0.0045	-0.006	NA	0.001	NA	-0.006	0.86	NA	0.30	NA	0.85

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
HbA1C	8.2	9.1	11.0	2.7	3.3
Schizophrenia (2014)	7.6	16.7	20.2	-4.5	-3.6
Bipolar Disorder or Schizophrenia	7.4	18.1	22.7	-4.8	-3.7
Schizophrenia (2018)	6.8	14.1	15.3	-3.6	-3.9
Worrier / anxious feelings	6.3	11.8	17.0	4.1	2.6
Exposure to tobacco smoke at home	6.3	7.1	8.4	2.4	2.9
Exposure to tobacco smoke outside home	6.1	8.1	10.2	3.2	2.5
Number of live births	6.0	8.4	8.9	-3.0	-2.8
Medication: Blood pressure	5.4	10.3	11.7	3.4	3.0
Number of incorrect matches in round	4.6	7.7	14.2	-3.8	-1.1
Medication for cholesterol	4.1	6.2	8.8	-1.9	-3.0
Medication: Omeprazole	3.8	4.6	6.9	-1.5	-2.6
Cholesterol lowering medication	3.3	4.9	6.7	1.7	2.6
Alcohol drinker status: Previous	3.3	3.7	6.0	-1.2	-2.4
Bipolar Disorder (2018)	3.2	5.0	8.9	-3.0	-1.0
Qualifications: NVQ or HND or HNC or equivalent	3.0	3.7	6.7	-2.6	-0.8
Fluid intelligence score	2.9	5.9	10.2	3.2	1.3
Neck or shoulder pain in last month	2.8	4.0	8.0	2.8	0.3
Blood Red Count	2.7	26.1	27.2	-5.0	-5.2
Comparative body size at age 10	2.7	7.4	14.7	3.8	-0.1
Illnesses of father: None of the above (group 1)	2.7	3.4	4.3	-1.5	-2.1
Supplements: Glucosamine	2.6	3.4	6.7	-0.4	-2.6
Pain type(s) experienced in last month: Hip pain	2.6	3.3	4.8	2.2	1.3
Primary Biliary Cirrhosis	2.5	3.5	4.6	-1.6	-2.1
Relative age of first facial hair	2.5	5.1	7.5	-2.7	-1.6
Supplements: Vitamin C	2.5	3.0	4.9	2.2	1.0
Intelligence (Savage-Jansen 2018)	2.2	6.9	11.0	3.3	1.7
Verbal and Numeric Reasoning (VNR)	2.2	5.2	9.2	3.0	1.1
Coronary Artery Disease (CAD)	2.2	2.6	3.4	1.3	1.9
Lung FVC	2.2	11.4	13.2	-3.6	-3.1
Age at first live birth	2.2	4.0	7.1	0.9	2.7
Fasting Glucose	2.1	2.5	4.0	1.0	2.0
Medication: Ramipril	2.1	2.7	5.3	0.1	-2.3
Time employed in main current job	2.1	2.5	5.0	2.2	-0.0
Leg pain on walking	2.1	2.7	4.2	-1.1	-2.0
Breast Cancer	2.0	4.8	8.1	2.8	1.3
Lupus	2.0	3.0	6.0	-0.1	2.4
Type 2 Diabetes (T2D) (2012)	2.0	2.4	3.6	1.9	1.1
Hair/balding pattern: Pattern 4	2.0	4.8	7.1	-2.7	-1.6
Heart disease (mother)	2.0	2.4	3.1	1.3	1.8
Worry (Nagel 2018)	1.9	3.9	7.5	2.7	0.6
Age when periods started (menarche)	1.9	4.5	6.8	-2.6	-1.5
Pulse rate	1.9	3.2	4.3	2.1	1.4
Schizophrenia vs Biploar Disorder	1.8	2.4	3.2	-1.3	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	4.0	-0.6	-2.0
Medication: Atorvastatin	1.8	2.3	3.6	-1.0	-1.9
Hearing difficulty/problems: Yes	1.7	2.5	3.3	-1.8	-1.3
Hair/balding pattern: Pattern 3	1.7	2.5	3.6	-1.2	-1.9
Osteoporosis (self-reported)	1.7	2.1	4.1	-0.2	-2.0
Average weekly champagne plus white wine intake	1.7	2.3	3.3	1.2	1.8
Guilty feelings	1.7	2.6	4.5	0.8	-2.1
Commuting to job workplace: Public transport	1.7	2.1	2.9	1.1	1.7
Medication: Omeprazole (e.g. Zanprol)	1.7	2.1	3.4	-0.9	-1.8
Neuroticism	1.5	3.7	7.3	2.7	-0.2
Frequency of depressed mood in last 2 weeks	1.5	2.0	3.7	0.6	-1.9
Birth weight	1.5	3.2	6.3	-2.5	-0.4
Mineral and other dietary supplements	1.5	2.0	2.3	1.3	1.5
Unable to work because of sickness or disability	1.5	1.9	2.1	1.3	1.4
Basal cell carcinoma (self-reported)	1.5	1.8	2.5	-1.1	-1.6
Fed-up feelings	1.4	2.5	4.9	-0.2	-2.2
Hearing difficulty/problems with background noise	1.4	2.3	2.6	-1.4	-1.6
Happiness	1.4	1.7	1.8	-1.3	-1.3
Breastfed as a baby	1.4	1.7	2.2	-1.5	-1.1
Qualifications: O levels/GCSEs or equivalent	1.4	2.3	3.7	1.9	0.9
Headache pain in last month	1.4	2.4	3.8	-1.0	-1.9
Friendships satisfaction	1.4	1.7	2.7	-0.9	-1.6
Tinnitus: Yes, now most or all of the time	1.4	1.6	2.0	-1.1	-1.4
Age at First Birth	1.3	1.9	3.3	0.7	1.8
Ulcerative Colitis	1.3	1.8	2.0	-1.4	-1.3
Supplements: Zinc	1.3	1.4	2.6	-0.4	-1.6
Medication: Amlodipine	1.3	1.8	2.8	0.9	1.7
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	4.1	0.4	-2.0
Back pain experienced in last month	1.3	1.8	3.6	1.9	0.2
Financial situation satisfaction	1.3	1.6	3.0	1.7	0.5
Chronotype (morning person)	1.2	2.7	5.2	2.3	0.5
Noisy workplace	1.2	1.5	2.5	-1.6	-0.8
Mouth/teeth dental problems: Dentures	1.2	2.0	3.9	-2.0	0.1
Illnesses of mother	1.2	1.5	2.3	0.8	1.5
Tense / ‘highly strung’	1.2	2.0	4.0	2.0	-0.3
Commuting to job workplace: Car/motor vehicle	1.2	1.4	2.0	0.9	1.4
Ever taken oral contraceptive pill	1.2	1.3	2.3	0.5	1.5
Irritability	1.2	2.1	4.1	2.0	0.2
Relative age voice broke	1.1	1.7	3.0	-1.7	-0.6
Falls in the last year	1.1	1.4	2.5	1.6	0.6
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	2.2	1.5	0.6
Suffer from ‘nerves’	1.1	1.7	3.4	1.9	0.2
Eye problems/disorders: Cataract	1.1	1.3	2.1	1.4	0.7
Miserableness	1.1	2.0	4.0	0.0	-2.0
Hearing aid user	1.1	1.3	1.8	-1.4	-0.8
Medication: Bendroflumethiazide	1.1	1.7	2.0	1.4	1.2
Depression (Nagel 2018)	1.0	1.5	2.5	1.6	-0.7
Respiratory disease	1.0	2.2	4.4	2.1	-0.3
Medication: Cholesterol lowering	1.0	1.6	1.6	-1.3	-1.2
Ever highly irritable/argumentative for 2 days	1.0	1.2	2.5	1.6	0.1
High blood pressure (siblings)	1.0	1.5	2.0	0.9	1.4
Arm fat-free mass (left)	1.0	5.1	5.2	-2.3	-2.2
Neuroticism (Nagel 2018)	0.9	2.1	4.0	2.0	-0.5
Alzheimer’s Disease (in mother)	0.9	1.1	1.3	-1.0	-1.1
Irritable Bowel Disease (IBD)	0.9	2.2	2.6	-1.4	-1.6
Ulcerative Colitis (UC)	0.9	1.7	2.6	-0.9	-1.6
Reaction Time	0.9	1.7	2.6	-0.8	1.6
Ovarian Cancer	0.9	1.2	2.0	1.4	0.7
Height	0.9	17.0	28.6	-5.3	-2.3
Average weekly spirits intake	0.9	1.2	2.2	-0.3	-1.5
Serious illness, injury or assault to yourself	0.9	1.1	1.4	1.2	-0.9
Alcohol usually taken with meals	0.9	1.4	1.6	-1.3	1.1
Had menopause	0.9	1.1	2.2	1.5	0.1
Alcohol intake versus 10 years previously	0.9	1.4	2.8	0.1	1.7
Standing height	0.9	8.6	14.2	-3.8	-1.8
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	2.2	0.9	1.5
Smoking status: Previous	0.9	1.3	2.5	-1.6	0.4
Arm predicted mass (left)	0.9	4.4	4.5	-2.1	-2.1
LDL Cholesterol	0.8	1.3	1.6	1.3	1.0
Diabetes (mother)	0.8	1.0	1.5	-0.7	-1.2
Sitting height	0.8	5.4	5.7	-2.2	-2.4
Medication: Simvastatin	0.8	1.2	2.0	0.6	1.4
Trunk fat-free mass	0.8	4.5	4.7	-2.2	-2.1
Prospective memory result	0.8	0.9	1.1	-1.1	0.9
Trunk predicted mass	0.8	4.5	4.7	-2.2	-2.1
Birth weight of first child	0.8	1.4	2.9	-1.7	0.1
Arm predicted mass (right)	0.8	4.0	4.1	-2.0	-2.0
Breast cancer (self-reported)	0.8	0.9	1.4	0.7	1.2
Osteoarthritis (self-reported)	0.8	1.0	1.9	0.3	1.4
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.0	1.4	-0.2
Angina	0.7	0.9	1.8	0.0	1.3
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	0.7	-0.8	-0.9
Past tobacco smoking	0.7	1.2	2.4	1.6	-0.1
Neuroticism score	0.7	1.4	2.5	1.6	-0.5
Qualifications: A levels/AS levels or equivalent	0.7	1.6	2.4	0.8	1.6
Asthma	0.7	1.3	1.6	1.3	-1.0
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	1.7	1.3	-0.2
Blood clot in the leg (DVT)	0.7	0.9	1.7	1.3	-0.4
Number of full brothers	0.7	0.9	1.4	-0.6	-1.2
Medication: Blood pressure	0.7	1.2	1.5	-1.0	-1.2
Angina (self-reported)	0.7	0.9	1.8	0.0	1.3
Medication: Seretide 50 evohaler	0.7	0.8	1.5	1.2	-0.3
Mean time to correctly identify matches	0.7	1.3	2.4	-1.5	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	1.5	1.2	0.5
Illnesses of father: Heart disease	0.7	0.9	1.1	0.9	1.0
Illnesses of siblings: Diabetes	0.7	0.9	1.7	1.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	1.5	-1.2	-1.2
Mother’s age at death	0.7	0.8	1.6	-0.2	-1.3
Number of operations (self-reported)	0.7	1.0	2.1	0.1	-1.4
Average weekly beer plus cider intake	0.7	1.1	1.9	1.4	-0.5
Fractured/broken bones in last 5 years	0.7	0.8	1.4	1.2	0.5
Depressed Affect (Nagel 2018)	0.6	1.3	1.7	1.3	-0.9
Crohns Disease (2017)	0.6	1.4	1.5	-1.2	-1.1
Crohns Disease (2012)	0.6	1.0	1.7	-1.3	-0.6
Cardiovascular Disease	0.6	2.0	2.2	1.5	1.4
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.2	-1.1	-0.1
Maternal smoking around birth	0.6	0.8	1.2	-1.1	-0.7
Forced vital capacity (FVC)	0.6	2.5	4.6	-2.1	-0.6
Pain all over the body in last month	0.6	0.7	1.3	0.2	1.2
Arm fat-free mass (right)	0.6	3.0	3.1	-1.7	-1.8
Health satisfaction	0.6	0.8	1.1	0.6	-1.1
Overall health rating	0.6	1.4	1.9	1.4	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	0.9	1.0	0.7
Asthma (self-reported)	0.6	1.2	1.5	1.2	-0.9
Supplements: Fish oil (including cod liver oil)	0.6	0.7	1.0	-1.0	-0.7
BMI	0.5	2.9	5.4	2.3	0.6
Townsend deprivation index at recruitment	0.5	0.7	1.4	-1.2	0.2
Medication: Paracetamol	0.5	0.9	1.2	-1.1	-0.7
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.0	-0.5	-1.0
Worry too long after embarrassment	0.5	0.8	0.8	0.9	-0.9
Wheeze or whistling in the chest in last year	0.5	0.9	1.8	1.3	0.2
Pulse rate, automated reading	0.5	1.6	1.7	1.3	1.2
Age at last live birth	0.5	0.8	0.8	-0.9	0.9
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	0.8	-0.9	-0.7
Hypertension (Self-reported)	0.5	1.3	1.4	1.1	1.2
Whole body fat-free mass	0.5	2.9	3.2	-1.6	-1.8
Qualifications: nursing, teaching	0.5	0.8	1.6	-0.2	-1.3
Whole body water mass	0.5	2.8	3.2	-1.6	-1.8
Vascular/heart problems diagnosed by doctor	0.5	1.3	1.7	-1.0	-1.3
Heel T-Score	0.4	3.2	6.2	-0.3	-2.5
Waist Hip Ratio (WHR)	0.4	1.8	3.2	1.8	0.6
Ever had hysterectomy (womb removed)	0.4	0.5	0.8	-0.9	0.3
Diabetes (father)	0.4	0.5	0.7	0.8	0.4
High blood pressure	0.4	1.1	1.3	0.9	1.1
Impedance of leg (left)	0.4	1.9	2.7	-1.0	1.7
Impedance of arm (left)	0.4	1.9	3.1	0.8	1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	0.8	0.9	-0.5
Eye problems/disorders: None of the above	0.4	0.5	0.7	0.6	0.8
Emphysema/chronic bronchitis	0.4	0.5	0.9	-1.0	0.1
Medication for pain relief, constipation, heartburn	0.4	0.6	0.8	0.7	0.9
Medication: Allopurinol	0.4	0.6	0.7	0.9	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.6	-0.1	1.3
Average weekly red wine intake	0.4	0.7	1.3	-1.1	0.1
Illnesses of father: High blood pressure	0.4	0.5	0.9	-0.2	1.0
Basal metabolic rate	0.4	2.2	2.3	-1.4	-1.5
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.0	0.1	-1.0
Heart disease (siblings)	0.4	0.5	0.8	-0.9	-0.3
HDL Cholesterol	0.3	0.5	1.0	-0.1	1.0
Triglycerides	0.3	0.5	0.9	-1.0	-0.3
Blood Platelet Count	0.3	3.3	6.0	2.5	0.8
Hand grip strength (left)	0.3	0.8	1.5	-0.2	-1.2
Medication: Co-codamol	0.3	0.3	0.6	0.1	-0.8
Impedance of leg (right)	0.3	1.6	1.6	-1.2	1.3
Hand grip strength (right)	0.3	0.9	1.7	-0.4	-1.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.7	-0.2	0.8
Medication: Levothyroxine sodium	0.3	0.6	0.9	-1.0	-0.4
Chronic bronchitis/emphysema (father)	0.3	0.4	0.5	0.7	-0.4
Nervous feelings	0.3	0.5	0.5	0.7	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.7	0.5	-0.8
Hair/balding pattern: Pattern 2	0.3	0.4	0.5	-0.5	0.7
Qualifications: None of the above	0.3	0.7	0.8	-0.9	-0.8
Allergy	0.3	0.8	1.0	-1.0	0.7
Illnesses of siblings	0.3	0.4	0.8	-0.9	-0.3
Impedance of arm (right)	0.3	1.2	2.4	0.2	1.6
Length of working week for main job	0.3	0.3	0.5	0.1	-0.7
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	0.8	-0.7	-0.9
Number of children fathered	0.3	0.3	0.4	-0.5	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.4	0.6	0.5
Qualifications: College or University degree	0.3	1.0	1.0	0.9	1.0
Migraine (self-reported)	0.3	0.4	0.7	-0.9	0.3
Medication: Aspirin	0.3	0.4	0.7	0.4	0.8
Mood swings	0.3	0.6	1.0	0.3	-1.0
Long-standing illness, disability or infirmity	0.3	0.5	0.9	0.2	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.6	-0.2	0.8
Number of self-reported non-cancer illnesses	0.3	0.5	0.5	0.6	-0.7
Medication: Lisinopril	0.3	0.4	0.7	-0.1	-0.9
Ever smoked	0.3	0.5	0.9	-0.9	0.3
Pain experienced in last month	0.3	0.4	0.6	-0.5	0.8
Supplements: Calcium	0.3	0.3	0.6	0.8	-0.0
Pack years of smoking	0.3	0.4	0.8	0.0	-0.9
Impedance of whole body	0.3	1.6	3.0	-0.3	1.7
Alzheimer’s Disease (including proxy)	0.2	0.2	0.3	-0.5	-0.4
Smoking Status	0.2	0.4	0.7	-0.3	0.8
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.4	0.7	0.2
Medication for hormone replacement therapy	0.2	0.2	0.4	0.1	0.6
Severe depression (siblings)	0.2	0.3	0.4	0.4	0.6
Average weekly fortified wine intake	0.2	0.3	0.5	0.7	0.0
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.5	-0.7	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	0.6	0.3	-0.8
Qualifications: CSEs or equivalent	0.2	0.3	0.5	-0.0	0.7
Multivitamins +/- minerals	0.2	0.2	0.4	-0.7	0.0
High blood pressure (mother)	0.2	0.2	0.3	0.4	-0.5
Had other major operations	0.2	0.3	0.4	0.3	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.0	-0.0	-1.0
Diabetes (self-reported)	0.2	0.3	0.7	-0.0	-0.8
Father’s age at death	0.2	0.2	0.4	-0.6	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.5	0.7	-0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.6	-1.3	0.0
Medication: Lansoprazole	0.2	0.2	0.5	0.7	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	1.0	-1.0	-0.2
Gout (self-reported)	0.2	0.3	0.5	0.7	0.2
Forced vital capacity (FVC), Best measure	0.2	0.7	1.4	-1.2	-0.2
Chest pain or discomfort	0.2	0.3	0.5	0.7	0.1
Family relationship satisfaction	0.2	0.2	0.4	-0.1	-0.7
Knee pain experienced in last month	0.2	0.4	0.7	-0.0	-0.8
Arm fat percentage (left)	0.2	0.8	1.5	1.2	0.4
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.4	-0.6	-0.4
Medication: Aspirin	0.2	0.3	0.5	0.2	0.7
Medication: Gliclazide	0.2	0.2	0.3	0.6	0.2
Risk taking	0.2	0.3	0.6	-0.8	-0.2
Age started oral contraceptive pill	0.2	0.2	0.4	-0.6	-0.2
Ever depressed for a whole week	0.2	0.2	0.4	0.1	-0.6
Alzheimer’s Disease (in father)	0.1	0.1	0.1	0.3	-0.1
Body Mass Index (BMI) (2010)	0.1	0.1	0.2	-0.4	0.1
Neuroticism (2016)	0.1	0.2	0.3	0.6	-0.0
Blood Eosinophil Count	0.1	0.5	0.9	0.1	1.0
Blood White Count	0.1	0.6	1.1	-0.2	1.0
Systolic Blood Pressure	0.1	0.3	0.4	-0.4	0.6
Tanning	0.1	1.1	1.3	1.1	0.9
Number of treatments/medications taken	0.1	0.2	0.4	-0.6	-0.3
Sensitivity / hurt feelings	0.1	0.2	0.2	-0.4	-0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.3	-0.1	-0.5
Vitamin and mineral supplements	0.1	0.1	0.1	-0.3	0.2
Medication: Metformin	0.1	0.2	0.3	0.3	-0.5
Pack years adult smoking proportion	0.1	0.1	0.2	0.2	-0.5
Leg fat-free mass (left)	0.1	0.7	1.1	-0.5	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.4	0.1	-0.6
Stomach or abdominal pain in last month	0.1	0.2	0.2	0.5	-0.4
Body mass index (BMI)	0.1	0.5	0.8	0.9	-0.3
Leg predicted mass (left)	0.1	0.6	1.0	-0.4	-1.0
Waist circumference	0.1	0.3	0.6	0.8	0.3
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.3	0.1	-0.6
Mouth/teeth dental problems	0.1	0.2	0.2	0.4	0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.1	0.4	0.3
Weight	0.1	0.7	0.9	-0.7	-1.0
Arm fat percentage (right)	0.1	0.4	0.8	0.9	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.1	0.1	-0.4
Lung cancer (father)	0.1	0.1	0.1	-0.3	-0.2
Pulse wave Arterial Stiffness index	0.1	0.1	0.2	0.4	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.4	0.1	-0.7
Pulse wave reflection index	0.1	0.2	0.2	-0.4	-0.5
Pulse wave peak to peak time	0.1	0.1	0.2	-0.4	-0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	-0.1	-0.4
Medication: Ibuprofen	0.1	0.2	0.3	0.1	-0.5
Alcohol intake frequency.	0.1	0.2	0.3	-0.6	-0.1
Comparative height size at age 10	0.1	0.6	1.1	-1.1	-0.2
Number of full sisters	0.1	0.1	0.2	-0.4	0.2
Leg fat-free mass (right)	0.1	0.4	0.7	-0.5	-0.8
Loneliness, isolation	0.1	0.1	0.2	0.4	-0.1
Diabetes diagnosed by doctor	0.1	0.2	0.4	-0.2	-0.6
Commuting to job workplace: Walk	0.1	0.1	0.1	-0.4	-0.1
Leg predicted mass (right)	0.1	0.5	0.7	-0.5	-0.9
Wears glasses or contact lenses	0.1	0.1	0.2	-0.3	0.5
Medication: Paracetamol	0.1	0.2	0.3	-0.3	-0.5
Leg fat percentage (left)	0.1	0.3	0.3	0.5	0.5
Diastolic blood pressure, automated reading	0.1	0.4	0.4	0.6	0.7
Myopia	0.1	0.2	0.2	-0.4	0.5
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.2	-0.4	-0.1
Major Depression (MDD)	0.0	0.0	0.0	0.0	-0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.1	-0.3	0.1
Rheumatoid Arthritis	0.0	0.0	0.1	0.1	-0.3
Allergy or Eczema	0.0	0.1	0.1	0.3	0.3
Hypothyroidism (self reported)	0.0	0.1	0.1	0.3	0.2
Type 2 Diabetes (T2D) (2018)	0.0	0.0	0.0	0.0	-0.2
Lung FEV1/FVC ratio	0.0	0.1	0.2	-0.4	-0.2
Hair Pigment	0.0	1.1	2.1	-1.5	0.1
Systolic blood pressure, automated reading	0.0	0.1	0.1	-0.3	0.3
Trunk fat percentage	0.0	0.1	0.2	0.4	0.3
Current tobacco smoking	0.0	0.0	0.0	0.2	0.1
Taking other prescription medications	0.0	0.0	0.1	-0.1	0.3
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.0	-0.1	-0.2
Medication: Atenolol	0.0	0.0	0.0	-0.2	0.2
Trunk fat mass	0.0	0.0	0.0	-0.1	-0.2
Financial difficulties in last 2 years	0.0	0.0	0.1	-0.0	-0.2
Heart attack	0.0	0.0	0.0	-0.2	0.0
Hip circumference	0.0	0.0	0.0	-0.1	0.1
Depression (self-reported)	0.0	0.0	0.1	-0.1	0.3
Arm fat mass (right)	0.0	0.1	0.1	0.2	-0.3
Peak expiratory flow (PEF)	0.0	0.0	0.0	0.2	-0.0
Loud music exposure frequency	0.0	0.0	0.0	0.2	0.0
Glaucoma (self-reported)	0.0	0.0	0.0	-0.1	0.2
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.0	-0.1	0.0
Body fat percentage	0.0	0.2	0.2	0.5	0.4
Leg fat percentage (right)	0.0	0.1	0.1	0.3	0.3
Shortness of breath walking on level ground	0.0	0.0	0.0	0.0	-0.0
Whole body fat mass	0.0	0.0	0.0	-0.1	-0.1
Leg fat mass (right)	0.0	0.0	0.0	0.0	0.0
Had major operations	0.0	0.1	0.1	0.2	-0.3
Ever had bowel cancer screening	0.0	0.0	0.0	-0.1	-0.2
Smoking status: Current	0.0	0.0	0.0	-0.1	-0.0
Arm fat mass (left)	0.0	0.1	0.1	0.2	-0.2
Eye problems/disorders: Glaucoma	0.0	0.0	0.0	-0.1	-0.2
High cholesterol (Self-reported)	0.0	0.0	0.0	-0.2	0.2
Alcohol drinker status: Never	0.0	0.0	0.0	0.1	0.1
Commuting to job workplace: Cycle	0.0	0.0	0.1	0.3	0.0
Leg fat mass (left)	0.0	0.0	0.0	0.2	0.2

Hub : Genes

LRRC73

Models

Trait associations