[Hub]/) : Traits : Height :

chr2:35,883,253-39,300,259

Best TWAS P=5.72e-52 · Best GWAS P=1.81e-46 conditioned to 2.72e-43

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FEZ2 0.16 0.24 lasso 2 0.22 1.3e-26 12.73 -12.7 4.8e-37 0.00 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous ATL2 0.13 0.02 lasso 5 0.04 2.2e-04 5.71 5.2 1.7e-07 -0.04 0.48 0.04 FALSE
3 GTEx Adipose Subcutaneous AC007401.1 0.10 0.02 lasso 4 0.02 5.4e-03 10.99 11.2 3.8e-29 -0.04 0.48 0.03 FALSE
4 GTEx Artery Tibial CYP1B1 0.16 0.06 lasso 5 0.07 3.8e-06 6.47 6.2 5.7e-10 -0.07 0.64 0.02 FALSE
5 GTEx Artery Tibial CRIM1 0.10 0.04 lasso 4 0.05 1.4e-04 10.99 -13.4 5.5e-41 0.03 0.10 0.86 FALSE
6 GTEx Artery Tibial RP11-78I14.1 0.10 0.08 enet 16 0.07 4.2e-06 10.99 -13.3 1.6e-40 0.07 0.17 0.75 FALSE
7 GTEx Brain Cerebellar Hemisphere CRIM1 0.36 0.21 lasso 5 0.16 5.4e-05 9.68 10.6 2.1e-26 -0.03 0.34 0.06 FALSE
8 GTEx Brain Cerebellar Hemisphere FEZ2 0.41 0.30 lasso 6 0.28 8.6e-08 10.73 10.7 8.6e-27 -0.01 0.82 0.02 FALSE
9 GTEx Brain Cerebellar Hemisphere AC007401.1 0.40 0.26 lasso 4 0.22 2.3e-06 9.68 10.5 1.3e-25 -0.02 0.73 0.02 FALSE
10 GTEx Brain Cerebellar Hemisphere RP11-490M8.1 0.37 0.18 lasso 4 0.15 1.2e-04 10.91 11.4 6.5e-30 -0.01 0.26 0.09 FALSE
11 GTEx Brain Cerebellum FEZ2 0.44 0.26 lasso 6 0.23 2.6e-07 10.01 9.4 6.7e-21 -0.01 0.93 0.02 FALSE
12 GTEx Brain Cerebellum AC007401.1 0.27 0.21 enet 5 0.20 1.5e-06 9.68 10.1 6.7e-24 -0.02 0.62 0.08 FALSE
13 GTEx Brain Cerebellum RP11-490M8.1 0.21 0.21 lasso 4 0.20 1.4e-06 9.64 9.9 2.6e-23 -0.03 0.58 0.06 FALSE
14 GTEx Heart Left Ventricle CRIM1 0.20 0.11 lasso 6 0.15 3.1e-08 -6.80 5.3 1.1e-07 0.02 0.88 0.00 FALSE
15 GTEx Heart Left Ventricle RP11-490M8.1 0.28 0.11 lasso 6 0.14 3.7e-08 -6.80 6.0 2.0e-09 0.05 0.99 0.00 FALSE
16 GTEx Skin Sun Exposed Lower leg RP11-78I14.1 0.14 0.06 enet 8 0.04 6.0e-04 -13.01 -11.8 5.7e-32 -0.01 0.04 0.90 FALSE
17 GTEx Spleen FEZ2 0.42 0.16 enet 25 0.17 3.9e-05 9.64 10.6 2.2e-26 -0.02 0.28 0.23 FALSE
18 GTEx Whole Blood FEZ2 0.11 0.09 enet 25 0.10 8.4e-10 10.73 7.3 4.0e-13 -0.04 1.00 0.00 FALSE
19 GTEx Whole Blood AC007401.1 0.06 0.06 lasso 5 0.05 4.6e-05 10.73 10.8 3.8e-27 0.00 0.78 0.01 FALSE
20 METSIM Adipose STRN 0.07 0.03 blup 624 0.03 8.3e-06 -0.56 5.4 6.9e-08 0.05 0.94 0.00 TRUE
21 NTR Blood CRIM1 0.09 0.10 lasso 6 0.11 3.1e-32 11.30 -11.6 5.4e-31 0.03 1.00 0.00 FALSE
22 ROSMAP Brain Pre-frontal Cortex NDUFAF7 0.13 0.07 enet 48 0.10 1.8e-12 -1.49 6.1 1.3e-09 0.03 1.00 0.00 TRUE
23 ROSMAP Brain Pre-frontal Cortex CYP1B1 0.08 0.00 blup 584 0.02 2.2e-03 -4.09 8.4 3.2e-17 0.06 0.12 0.03 TRUE
24 ROSMAP Brain Pre-frontal Cortex FEZ2 0.41 0.55 lasso 5 0.58 3.1e-93 11.43 -11.8 2.5e-32 0.02 1.00 0.00 FALSE
25 YFS Blood FEZ2 0.40 0.52 bslmm 615 0.55 7.7e-222 10.76 7.8 6.1e-15 -0.02 1.00 0.00 FALSE
26 The Cancer Genome Atlas Breast Invasive Carcinoma FEZ2 0.01 0.01 blup 85 0.01 1.0e-03 10.95 -13.5 1.1e-41 0.01 0.31 0.10 FALSE
27 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FEZ2 0.06 0.05 lasso 4 0.04 3.3e-03 11.98 -11.6 4.3e-31 0.03 0.20 0.06 FALSE
28 The Cancer Genome Atlas Colon Adenocarcinoma FEZ2 0.11 0.03 blup 84 0.07 6.1e-05 12.73 -9.2 4.5e-20 0.02 0.58 0.03 FALSE
29 The Cancer Genome Atlas Esophageal Carcinoma FEZ2 0.11 0.01 blup 87 0.02 7.1e-02 10.01 -10.0 2.1e-23 0.01 0.06 0.04 FALSE
30 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FEZ2 0.04 0.00 blup 88 0.02 6.1e-03 9.97 -8.8 1.6e-18 0.01 0.13 0.02 FALSE
31 The Cancer Genome Atlas Prostate Adenocarcinoma CRIM1 0.05 0.04 lasso 2 0.03 3.2e-04 -9.51 -9.5 2.6e-21 -0.01 0.23 0.19 FALSE
32 The Cancer Genome Atlas Prostate Adenocarcinoma FEZ2 0.06 0.05 blup 87 0.08 1.4e-08 11.43 -10.6 2.5e-26 0.01 1.00 0.00 FALSE
33 The Cancer Genome Atlas Stomach Adenocarcinoma FAM82A1 0.05 0.03 blup 135 0.03 3.0e-03 -2.78 5.6 1.9e-08 0.05 0.04 0.52 FALSE
34 The Cancer Genome Atlas Stomach Adenocarcinoma QPCT 0.07 0.00 blup 68 0.04 1.3e-03 3.05 -6.5 1.1e-10 -0.02 0.01 0.17 TRUE
35 The Cancer Genome Atlas Testicular Germ Cell Tumors FEZ2 0.18 0.21 lasso 6 0.21 5.3e-08 -14.18 -15.2 5.7e-52 0.02 0.00 1.00 TRUE
36 The Cancer Genome Atlas Thyroid Carcinoma FEZ2 0.07 0.06 blup 87 0.06 2.4e-06 10.91 -8.0 1.5e-15 0.02 0.97 0.00 FALSE