[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr19:16,462,417-19,374,068

Best TWAS P=6.8e-41 · Best GWAS P=3.77e-39 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	KIAA1683	0.09	0.06	enet	14	0.10	6.6e-12	-8.29	11.3	1.4e-29	0.78	0.02	0.98	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PDE4C	0.14	0.16	lasso	4	0.15	2.8e-18	-8.15	-7.9	2.9e-15	-0.46	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	KIAA1683	0.14	0.09	enet	6	0.16	2.5e-13	-7.27	10.9	1.2e-27	0.80	0.01	0.99	FALSE
4	GTEx	Adipose Subcutaneous	AC005253.4	0.11	0.06	enet	23	0.04	1.6e-04	-1.44	7.2	7.9e-13	0.38	0.18	0.54	FALSE
5	GTEx	Adrenal Gland	KIAA1683	0.26	0.05	enet	21	0.19	1.7e-07	-7.38	7.7	1.0e-14	0.58	0.05	0.92	FALSE
6	GTEx	Artery Tibial	KIAA1683	0.16	0.08	enet	11	0.15	8.2e-12	-7.27	8.8	1.9e-18	0.60	0.48	0.52	FALSE
7	GTEx	Artery Tibial	HAUS8	0.16	0.02	lasso	7	0.02	4.7e-03	4.96	-5.8	6.2e-09	-0.02	0.26	0.65	FALSE
8	GTEx	Artery Tibial	CTD-3032J10.3	0.14	0.01	lasso	5	0.01	6.4e-02	7.54	-7.3	2.4e-13	0.00	0.00	0.94	TRUE
9	GTEx	Breast Mammary Tissue	KIAA1683	0.17	0.10	lasso	5	0.07	1.2e-04	-8.68	9.0	2.3e-19	0.60	0.08	0.91	FALSE
10	GTEx	Breast Mammary Tissue (Female)	KIAA1683	0.18	0.03	lasso	2	0.03	5.2e-02	-7.33	7.3	2.0e-13	0.42	0.04	0.25	FALSE
11	GTEx	Cells Transformed fibroblasts	KIAA1683	0.14	0.16	lasso	2	0.15	1.2e-11	-7.27	8.9	8.2e-19	0.61	0.87	0.13	FALSE
12	GTEx	Cells Transformed fibroblasts	HAUS8	0.12	0.05	enet	19	0.05	1.0e-04	4.96	-6.3	2.4e-10	-0.04	0.43	0.44	FALSE
13	GTEx	Cells Transformed fibroblasts	AC005253.2	0.15	0.01	enet	23	0.03	1.3e-03	-1.44	5.3	1.1e-07	0.18	0.21	0.14	TRUE
14	GTEx	Colon Sigmoid	KIAA1683	0.15	0.09	lasso	6	0.09	5.1e-04	-8.68	9.8	9.4e-23	0.67	0.03	0.91	FALSE
15	GTEx	Colon Transverse	SSBP4	0.18	0.01	enet	21	0.00	3.6e-01	6.70	-7.6	4.2e-14	-0.38	0.06	0.23	FALSE
16	GTEx	Colon Transverse	KIAA1683	0.15	0.02	lasso	3	0.02	3.3e-02	-8.68	12.1	1.2e-33	0.87	0.00	0.98	FALSE
17	GTEx	Esophagus Muscularis	MYO9B	0.13	0.02	lasso	5	0.05	9.5e-04	2.49	-6.1	9.1e-10	-0.02	0.05	0.93	FALSE
18	GTEx	Esophagus Muscularis	KIAA1683	0.10	0.04	lasso	3	0.06	1.1e-04	-7.27	11.1	9.2e-29	0.80	0.01	0.99	FALSE
19	GTEx	Heart Atrial Appendage	KIAA1683	0.15	0.03	lasso	5	0.10	2.4e-05	13.09	9.1	7.5e-20	0.67	0.01	0.97	FALSE
20	GTEx	Heart Left Ventricle	KIAA1683	0.20	0.03	lasso	7	0.15	2.9e-08	-8.68	9.0	1.6e-19	0.67	0.01	0.99	FALSE
21	GTEx	Muscle Skeletal	PDE4C	0.11	0.05	lasso	6	0.06	7.7e-07	-7.40	-9.1	7.7e-20	-0.54	0.98	0.02	FALSE
22	GTEx	Muscle Skeletal	HAUS8	0.15	0.10	lasso	4	0.08	1.6e-08	5.00	-5.6	2.2e-08	-0.01	1.00	0.00	FALSE
23	GTEx	Muscle Skeletal	AC068499.10	0.10	0.07	lasso	4	0.07	2.5e-07	-8.65	-9.0	1.7e-19	-0.55	0.92	0.07	FALSE
24	GTEx	Nerve Tibial	KIAA1683	0.25	0.22	lasso	9	0.28	5.2e-20	13.04	12.4	3.8e-35	0.87	0.00	1.00	FALSE
25	GTEx	Ovary	PGPEP1	0.42	0.18	enet	31	0.14	3.5e-04	2.25	-7.2	4.4e-13	-0.29	0.09	0.10	TRUE
26	GTEx	Pancreas	AC007192.6	0.19	0.00	enet	28	0.01	1.3e-01	8.37	-8.1	5.0e-16	-0.48	0.06	0.24	FALSE
27	GTEx	Pituitary	KIAA1683	0.43	0.25	lasso	3	0.17	3.9e-05	10.98	10.7	8.9e-27	0.80	0.01	0.93	FALSE
28	GTEx	Prostate	KIAA1683	0.20	0.27	lasso	1	0.23	1.8e-06	-7.27	7.3	3.7e-13	0.48	0.29	0.10	FALSE
29	GTEx	Skin Not Sun Exposed Suprapubic	KIAA1683	0.16	0.05	enet	12	0.06	3.5e-04	-7.27	8.7	2.4e-18	0.64	0.22	0.74	FALSE
30	GTEx	Skin Sun Exposed Lower leg	KIAA1683	0.09	0.04	enet	9	0.06	1.0e-05	-7.27	6.6	4.0e-11	0.49	0.39	0.52	FALSE
31	GTEx	Spleen	KIAA1683	0.26	0.17	lasso	6	0.13	3.9e-04	-7.27	8.2	3.4e-16	0.52	0.28	0.18	FALSE
32	GTEx	Thyroid	KIAA1683	0.11	0.07	enet	14	0.12	2.1e-09	10.98	11.8	2.8e-32	0.75	0.02	0.97	FALSE
33	GTEx	Vagina	LRRC25	0.63	0.02	enet	2	0.04	5.3e-02	13.04	-13.1	4.2e-39	-1.00	0.01	0.72	FALSE
34	METSIM	Adipose	IFI30	0.03	0.01	blup	420	0.02	2.6e-04	-7.50	8.3	7.1e-17	0.38	0.35	0.22	FALSE
35	METSIM	Adipose	IL12RB1	0.05	0.05	lasso	3	0.04	2.8e-07	6.51	-6.1	1.4e-09	-0.29	0.98	0.01	FALSE
36	METSIM	Adipose	KIAA1683	0.21	0.24	enet	21	0.27	2.1e-40	-7.28	9.6	7.7e-22	0.62	1.00	0.00	FALSE
37	NTR	Blood	IFI30	0.03	0.02	lasso	6	0.02	8.8e-08	8.53	8.4	4.4e-17	0.47	0.98	0.00	FALSE
38	ROSMAP	Brain Pre-frontal Cortex	PDE4C	0.18	0.12	enet	17	0.19	3.3e-24	-8.15	-9.7	2.0e-22	-0.57	1.00	0.00	TRUE
39	ROSMAP	Brain Pre-frontal Cortex	KIAA1683	0.23	0.14	bslmm	409	0.24	1.4e-30	-7.27	11.0	3.7e-28	0.83	0.00	1.00	TRUE
40	ROSMAP	Brain Pre-frontal Cortex	JUND	0.17	0.17	lasso	5	0.20	2.7e-25	13.04	12.9	6.7e-38	0.92	0.00	1.00	FALSE
41	ROSMAP	Brain Pre-frontal Cortex	HAUS8	0.05	0.05	enet	7	0.05	7.1e-07	4.93	-5.1	3.1e-07	0.00	0.41	0.58	FALSE
42	YFS	Blood	IFI30	0.08	0.04	bslmm	405	0.08	1.1e-23	-3.51	7.2	7.3e-13	0.42	1.00	0.00	FALSE
43	YFS	Blood	KIAA1683	0.51	0.40	enet	65	0.46	9.9e-171	13.09	11.8	4.4e-32	0.91	0.00	1.00	FALSE
44	YFS	Blood	MAST3	0.06	0.04	lasso	5	0.04	4.2e-12	8.37	-7.9	2.6e-15	-0.40	1.00	0.00	FALSE
45	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IL12RB1	0.07	0.02	lasso	3	0.01	6.4e-02	6.51	-6.3	2.5e-10	-0.32	0.13	0.16	TRUE
46	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	KIAA1683	0.05	0.04	enet	6	0.05	4.9e-05	-7.27	10.4	3.2e-25	0.73	0.05	0.88	FALSE
47	The Cancer Genome Atlas	Breast Invasive Carcinoma	HAUS8	0.05	0.06	enet	12	0.06	2.9e-12	5.00	-5.5	4.0e-08	-0.01	1.00	0.00	FALSE
48	The Cancer Genome Atlas	Breast Invasive Carcinoma	KIAA1683	0.04	0.02	blup	65	0.03	2.6e-07	-7.35	8.2	1.8e-16	0.62	0.71	0.26	FALSE
49	The Cancer Genome Atlas	Colon Adenocarcinoma	HAUS8	0.12	0.06	lasso	5	0.06	1.8e-04	4.96	-5.4	5.5e-08	-0.05	0.22	0.62	FALSE
50	The Cancer Genome Atlas	Colon Adenocarcinoma	ISYNA1	0.08	0.09	lasso	4	0.09	7.0e-06	-5.28	-5.3	1.4e-07	0.04	0.00	0.99	FALSE
51	The Cancer Genome Atlas	Glioblastoma Multiforme	JUND	0.17	0.00	blup	57	0.03	5.4e-02	13.04	13.4	6.8e-41	0.71	0.00	0.70	TRUE
52	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HAUS8	0.08	0.07	blup	55	0.07	6.7e-08	4.96	-5.6	2.0e-08	-0.01	0.99	0.01	FALSE
53	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	KIAA1683	0.05	0.03	lasso	4	0.04	9.1e-06	-8.29	10.1	3.4e-24	0.68	0.16	0.84	FALSE
54	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ELL	0.06	0.01	blup	48	0.03	4.8e-04	-5.28	-5.9	3.1e-09	0.05	0.01	0.95	TRUE
55	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL12RB1	0.10	0.08	blup	58	0.09	6.9e-10	6.70	-6.3	3.0e-10	-0.29	1.00	0.00	FALSE
56	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	JUND	0.05	0.04	lasso	1	0.04	4.3e-05	13.04	13.0	6.8e-39	1.00	0.00	0.99	FALSE
57	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	KIAA1683	0.09	0.07	lasso	8	0.12	2.1e-13	-7.35	10.8	3.7e-27	0.75	0.24	0.76	FALSE
58	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MAST3	0.04	0.02	blup	65	0.01	7.3e-02	8.37	-6.0	1.7e-09	-0.32	0.01	0.52	FALSE
59	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	JUND	0.11	0.03	blup	58	0.04	1.4e-03	-0.77	9.7	2.6e-22	0.57	0.03	0.43	TRUE
60	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	KIAA1683	0.13	0.02	blup	65	0.05	1.0e-03	11.10	10.8	3.4e-27	0.79	0.00	0.98	FALSE
61	The Cancer Genome Atlas	Brain Lower Grade Glioma	IL12RB1	0.05	0.03	lasso	3	0.03	1.3e-04	6.51	-6.0	1.9e-09	-0.29	0.27	0.34	FALSE
62	The Cancer Genome Atlas	Brain Lower Grade Glioma	JUND	0.04	0.03	lasso	2	0.02	7.9e-04	13.04	13.1	4.6e-39	0.99	0.00	0.99	FALSE
63	The Cancer Genome Atlas	Brain Lower Grade Glioma	KIAA1683	0.16	0.11	lasso	6	0.11	2.9e-12	-7.27	10.1	4.6e-24	0.70	0.88	0.12	FALSE
64	The Cancer Genome Atlas	Lung Adenocarcinoma	ARRDC2	0.04	0.01	enet	7	0.03	5.3e-04	2.48	5.2	1.6e-07	0.15	0.02	0.05	FALSE
65	The Cancer Genome Atlas	Lung Adenocarcinoma	IL12RB1	0.10	0.08	enet	13	0.07	3.9e-08	6.70	-7.3	3.7e-13	-0.29	0.99	0.01	FALSE
66	The Cancer Genome Atlas	Lung Adenocarcinoma	KIAA1683	0.04	0.04	lasso	4	0.05	2.5e-06	-8.29	8.7	4.8e-18	0.59	0.72	0.22	FALSE
67	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IL12RB1	0.07	0.04	blup	58	0.06	4.9e-07	4.18	-6.9	5.8e-12	-0.26	0.88	0.10	FALSE
68	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	KIAA1683	0.09	0.05	lasso	4	0.06	1.3e-07	13.04	11.8	2.3e-32	0.86	0.00	1.00	FALSE
69	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	KIAA1683	0.09	0.06	blup	64	0.07	2.2e-05	-7.27	8.2	3.4e-16	0.53	0.83	0.09	TRUE
70	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	HAUS8	0.20	0.13	lasso	2	0.11	2.4e-05	5.00	-5.2	2.1e-07	-0.01	0.31	0.41	FALSE
71	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	KIAA1683	0.08	-0.01	blup	64	0.02	3.4e-02	13.04	7.8	7.3e-15	0.66	0.01	0.77	TRUE
72	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	HAUS8	0.21	0.11	enet	9	0.10	6.2e-05	-6.72	-6.8	1.5e-11	0.02	0.08	0.57	FALSE
73	The Cancer Genome Atlas	Prostate Adenocarcinoma	KIAA1683	0.06	0.02	blup	65	0.04	3.2e-05	-8.68	8.9	4.7e-19	0.69	0.09	0.87	FALSE
74	The Cancer Genome Atlas	Prostate Adenocarcinoma	MYO9B	0.14	0.07	blup	103	0.10	5.0e-11	7.54	-5.7	9.6e-09	-0.05	0.00	1.00	FALSE
75	The Cancer Genome Atlas	Soft Tissue Sarcoma	KIAA1683	0.07	0.00	blup	64	0.01	4.5e-02	-8.84	10.8	2.2e-27	0.59	0.01	0.68	FALSE
76	The Cancer Genome Atlas	Stomach Adenocarcinoma	HAUS8	0.06	0.04	blup	55	0.04	1.0e-03	4.92	-6.4	1.6e-10	0.01	0.04	0.41	FALSE
77	The Cancer Genome Atlas	Testicular Germ Cell Tumors	KIAA1683	0.17	0.06	blup	65	0.06	3.0e-03	-6.60	9.4	3.8e-21	0.68	0.01	0.93	FALSE
78	The Cancer Genome Atlas	Thyroid Carcinoma	HAUS8	0.04	0.06	lasso	2	0.05	2.2e-05	5.00	-5.5	3.8e-08	-0.01	0.10	0.87	FALSE
79	The Cancer Genome Atlas	Thyroid Carcinoma	IL12RB1	0.08	0.04	lasso	3	0.05	8.9e-06	3.53	-5.8	5.6e-09	-0.25	0.28	0.55	FALSE
80	The Cancer Genome Atlas	Thyroid Carcinoma	KIAA1683	0.15	0.09	lasso	6	0.16	5.4e-15	11.10	10.8	3.5e-27	0.75	0.64	0.36	FALSE