[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr19:16,462,417-19,374,068

Best TWAS P=6.8e-41 · Best GWAS P=3.77e-39 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KIAA1683 0.09 0.06 enet 14 0.10 6.6e-12 -8.29 11.3 1.4e-29 0.78 0.02 0.98 FALSE
2 CommonMind Brain Pre-frontal Cortex PDE4C 0.14 0.16 lasso 4 0.15 2.8e-18 -8.15 -7.9 2.9e-15 -0.46 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous KIAA1683 0.14 0.09 enet 6 0.16 2.5e-13 -7.27 10.9 1.2e-27 0.80 0.01 0.99 FALSE
4 GTEx Adipose Subcutaneous AC005253.4 0.11 0.06 enet 23 0.04 1.6e-04 -1.44 7.2 7.9e-13 0.38 0.18 0.54 FALSE
5 GTEx Adrenal Gland KIAA1683 0.26 0.05 enet 21 0.19 1.7e-07 -7.38 7.7 1.0e-14 0.58 0.05 0.92 FALSE
6 GTEx Artery Tibial KIAA1683 0.16 0.08 enet 11 0.15 8.2e-12 -7.27 8.8 1.9e-18 0.60 0.48 0.52 FALSE
7 GTEx Artery Tibial HAUS8 0.16 0.02 lasso 7 0.02 4.7e-03 4.96 -5.8 6.2e-09 -0.02 0.26 0.65 FALSE
8 GTEx Artery Tibial CTD-3032J10.3 0.14 0.01 lasso 5 0.01 6.4e-02 7.54 -7.3 2.4e-13 0.00 0.00 0.94 TRUE
9 GTEx Breast Mammary Tissue KIAA1683 0.17 0.10 lasso 5 0.07 1.2e-04 -8.68 9.0 2.3e-19 0.60 0.08 0.91 FALSE
10 GTEx Breast Mammary Tissue (Female) KIAA1683 0.18 0.03 lasso 2 0.03 5.2e-02 -7.33 7.3 2.0e-13 0.42 0.04 0.25 FALSE
11 GTEx Cells Transformed fibroblasts KIAA1683 0.14 0.16 lasso 2 0.15 1.2e-11 -7.27 8.9 8.2e-19 0.61 0.87 0.13 FALSE
12 GTEx Cells Transformed fibroblasts HAUS8 0.12 0.05 enet 19 0.05 1.0e-04 4.96 -6.3 2.4e-10 -0.04 0.43 0.44 FALSE
13 GTEx Cells Transformed fibroblasts AC005253.2 0.15 0.01 enet 23 0.03 1.3e-03 -1.44 5.3 1.1e-07 0.18 0.21 0.14 TRUE
14 GTEx Colon Sigmoid KIAA1683 0.15 0.09 lasso 6 0.09 5.1e-04 -8.68 9.8 9.4e-23 0.67 0.03 0.91 FALSE
15 GTEx Colon Transverse SSBP4 0.18 0.01 enet 21 0.00 3.6e-01 6.70 -7.6 4.2e-14 -0.38 0.06 0.23 FALSE
16 GTEx Colon Transverse KIAA1683 0.15 0.02 lasso 3 0.02 3.3e-02 -8.68 12.1 1.2e-33 0.87 0.00 0.98 FALSE
17 GTEx Esophagus Muscularis MYO9B 0.13 0.02 lasso 5 0.05 9.5e-04 2.49 -6.1 9.1e-10 -0.02 0.05 0.93 FALSE
18 GTEx Esophagus Muscularis KIAA1683 0.10 0.04 lasso 3 0.06 1.1e-04 -7.27 11.1 9.2e-29 0.80 0.01 0.99 FALSE
19 GTEx Heart Atrial Appendage KIAA1683 0.15 0.03 lasso 5 0.10 2.4e-05 13.09 9.1 7.5e-20 0.67 0.01 0.97 FALSE
20 GTEx Heart Left Ventricle KIAA1683 0.20 0.03 lasso 7 0.15 2.9e-08 -8.68 9.0 1.6e-19 0.67 0.01 0.99 FALSE
21 GTEx Muscle Skeletal PDE4C 0.11 0.05 lasso 6 0.06 7.7e-07 -7.40 -9.1 7.7e-20 -0.54 0.98 0.02 FALSE
22 GTEx Muscle Skeletal HAUS8 0.15 0.10 lasso 4 0.08 1.6e-08 5.00 -5.6 2.2e-08 -0.01 1.00 0.00 FALSE
23 GTEx Muscle Skeletal AC068499.10 0.10 0.07 lasso 4 0.07 2.5e-07 -8.65 -9.0 1.7e-19 -0.55 0.92 0.07 FALSE
24 GTEx Nerve Tibial KIAA1683 0.25 0.22 lasso 9 0.28 5.2e-20 13.04 12.4 3.8e-35 0.87 0.00 1.00 FALSE
25 GTEx Ovary PGPEP1 0.42 0.18 enet 31 0.14 3.5e-04 2.25 -7.2 4.4e-13 -0.29 0.09 0.10 TRUE
26 GTEx Pancreas AC007192.6 0.19 0.00 enet 28 0.01 1.3e-01 8.37 -8.1 5.0e-16 -0.48 0.06 0.24 FALSE
27 GTEx Pituitary KIAA1683 0.43 0.25 lasso 3 0.17 3.9e-05 10.98 10.7 8.9e-27 0.80 0.01 0.93 FALSE
28 GTEx Prostate KIAA1683 0.20 0.27 lasso 1 0.23 1.8e-06 -7.27 7.3 3.7e-13 0.48 0.29 0.10 FALSE
29 GTEx Skin Not Sun Exposed Suprapubic KIAA1683 0.16 0.05 enet 12 0.06 3.5e-04 -7.27 8.7 2.4e-18 0.64 0.22 0.74 FALSE
30 GTEx Skin Sun Exposed Lower leg KIAA1683 0.09 0.04 enet 9 0.06 1.0e-05 -7.27 6.6 4.0e-11 0.49 0.39 0.52 FALSE
31 GTEx Spleen KIAA1683 0.26 0.17 lasso 6 0.13 3.9e-04 -7.27 8.2 3.4e-16 0.52 0.28 0.18 FALSE
32 GTEx Thyroid KIAA1683 0.11 0.07 enet 14 0.12 2.1e-09 10.98 11.8 2.8e-32 0.75 0.02 0.97 FALSE
33 GTEx Vagina LRRC25 0.63 0.02 enet 2 0.04 5.3e-02 13.04 -13.1 4.2e-39 -1.00 0.01 0.72 FALSE
34 METSIM Adipose IFI30 0.03 0.01 blup 420 0.02 2.6e-04 -7.50 8.3 7.1e-17 0.38 0.35 0.22 FALSE
35 METSIM Adipose IL12RB1 0.05 0.05 lasso 3 0.04 2.8e-07 6.51 -6.1 1.4e-09 -0.29 0.98 0.01 FALSE
36 METSIM Adipose KIAA1683 0.21 0.24 enet 21 0.27 2.1e-40 -7.28 9.6 7.7e-22 0.62 1.00 0.00 FALSE
37 NTR Blood IFI30 0.03 0.02 lasso 6 0.02 8.8e-08 8.53 8.4 4.4e-17 0.47 0.98 0.00 FALSE
38 ROSMAP Brain Pre-frontal Cortex PDE4C 0.18 0.12 enet 17 0.19 3.3e-24 -8.15 -9.7 2.0e-22 -0.57 1.00 0.00 TRUE
39 ROSMAP Brain Pre-frontal Cortex KIAA1683 0.23 0.14 bslmm 409 0.24 1.4e-30 -7.27 11.0 3.7e-28 0.83 0.00 1.00 TRUE
40 ROSMAP Brain Pre-frontal Cortex JUND 0.17 0.17 lasso 5 0.20 2.7e-25 13.04 12.9 6.7e-38 0.92 0.00 1.00 FALSE
41 ROSMAP Brain Pre-frontal Cortex HAUS8 0.05 0.05 enet 7 0.05 7.1e-07 4.93 -5.1 3.1e-07 0.00 0.41 0.58 FALSE
42 YFS Blood IFI30 0.08 0.04 bslmm 405 0.08 1.1e-23 -3.51 7.2 7.3e-13 0.42 1.00 0.00 FALSE
43 YFS Blood KIAA1683 0.51 0.40 enet 65 0.46 9.9e-171 13.09 11.8 4.4e-32 0.91 0.00 1.00 FALSE
44 YFS Blood MAST3 0.06 0.04 lasso 5 0.04 4.2e-12 8.37 -7.9 2.6e-15 -0.40 1.00 0.00 FALSE
45 The Cancer Genome Atlas Bladder Urothelial Carcinoma IL12RB1 0.07 0.02 lasso 3 0.01 6.4e-02 6.51 -6.3 2.5e-10 -0.32 0.13 0.16 TRUE
46 The Cancer Genome Atlas Bladder Urothelial Carcinoma KIAA1683 0.05 0.04 enet 6 0.05 4.9e-05 -7.27 10.4 3.2e-25 0.73 0.05 0.88 FALSE
47 The Cancer Genome Atlas Breast Invasive Carcinoma HAUS8 0.05 0.06 enet 12 0.06 2.9e-12 5.00 -5.5 4.0e-08 -0.01 1.00 0.00 FALSE
48 The Cancer Genome Atlas Breast Invasive Carcinoma KIAA1683 0.04 0.02 blup 65 0.03 2.6e-07 -7.35 8.2 1.8e-16 0.62 0.71 0.26 FALSE
49 The Cancer Genome Atlas Colon Adenocarcinoma HAUS8 0.12 0.06 lasso 5 0.06 1.8e-04 4.96 -5.4 5.5e-08 -0.05 0.22 0.62 FALSE
50 The Cancer Genome Atlas Colon Adenocarcinoma ISYNA1 0.08 0.09 lasso 4 0.09 7.0e-06 -5.28 -5.3 1.4e-07 0.04 0.00 0.99 FALSE
51 The Cancer Genome Atlas Glioblastoma Multiforme JUND 0.17 0.00 blup 57 0.03 5.4e-02 13.04 13.4 6.8e-41 0.71 0.00 0.70 TRUE
52 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HAUS8 0.08 0.07 blup 55 0.07 6.7e-08 4.96 -5.6 2.0e-08 -0.01 0.99 0.01 FALSE
53 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma KIAA1683 0.05 0.03 lasso 4 0.04 9.1e-06 -8.29 10.1 3.4e-24 0.68 0.16 0.84 FALSE
54 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ELL 0.06 0.01 blup 48 0.03 4.8e-04 -5.28 -5.9 3.1e-09 0.05 0.01 0.95 TRUE
55 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IL12RB1 0.10 0.08 blup 58 0.09 6.9e-10 6.70 -6.3 3.0e-10 -0.29 1.00 0.00 FALSE
56 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma JUND 0.05 0.04 lasso 1 0.04 4.3e-05 13.04 13.0 6.8e-39 1.00 0.00 0.99 FALSE
57 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma KIAA1683 0.09 0.07 lasso 8 0.12 2.1e-13 -7.35 10.8 3.7e-27 0.75 0.24 0.76 FALSE
58 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MAST3 0.04 0.02 blup 65 0.01 7.3e-02 8.37 -6.0 1.7e-09 -0.32 0.01 0.52 FALSE
59 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma JUND 0.11 0.03 blup 58 0.04 1.4e-03 -0.77 9.7 2.6e-22 0.57 0.03 0.43 TRUE
60 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma KIAA1683 0.13 0.02 blup 65 0.05 1.0e-03 11.10 10.8 3.4e-27 0.79 0.00 0.98 FALSE
61 The Cancer Genome Atlas Brain Lower Grade Glioma IL12RB1 0.05 0.03 lasso 3 0.03 1.3e-04 6.51 -6.0 1.9e-09 -0.29 0.27 0.34 FALSE
62 The Cancer Genome Atlas Brain Lower Grade Glioma JUND 0.04 0.03 lasso 2 0.02 7.9e-04 13.04 13.1 4.6e-39 0.99 0.00 0.99 FALSE
63 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA1683 0.16 0.11 lasso 6 0.11 2.9e-12 -7.27 10.1 4.6e-24 0.70 0.88 0.12 FALSE
64 The Cancer Genome Atlas Lung Adenocarcinoma ARRDC2 0.04 0.01 enet 7 0.03 5.3e-04 2.48 5.2 1.6e-07 0.15 0.02 0.05 FALSE
65 The Cancer Genome Atlas Lung Adenocarcinoma IL12RB1 0.10 0.08 enet 13 0.07 3.9e-08 6.70 -7.3 3.7e-13 -0.29 0.99 0.01 FALSE
66 The Cancer Genome Atlas Lung Adenocarcinoma KIAA1683 0.04 0.04 lasso 4 0.05 2.5e-06 -8.29 8.7 4.8e-18 0.59 0.72 0.22 FALSE
67 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IL12RB1 0.07 0.04 blup 58 0.06 4.9e-07 4.18 -6.9 5.8e-12 -0.26 0.88 0.10 FALSE
68 The Cancer Genome Atlas Lung Squamous Cell Carcinoma KIAA1683 0.09 0.05 lasso 4 0.06 1.3e-07 13.04 11.8 2.3e-32 0.86 0.00 1.00 FALSE
69 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma KIAA1683 0.09 0.06 blup 64 0.07 2.2e-05 -7.27 8.2 3.4e-16 0.53 0.83 0.09 TRUE
70 The Cancer Genome Atlas Pancreatic Adenocarcinoma HAUS8 0.20 0.13 lasso 2 0.11 2.4e-05 5.00 -5.2 2.1e-07 -0.01 0.31 0.41 FALSE
71 The Cancer Genome Atlas Pancreatic Adenocarcinoma KIAA1683 0.08 -0.01 blup 64 0.02 3.4e-02 13.04 7.8 7.3e-15 0.66 0.01 0.77 TRUE
72 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma HAUS8 0.21 0.11 enet 9 0.10 6.2e-05 -6.72 -6.8 1.5e-11 0.02 0.08 0.57 FALSE
73 The Cancer Genome Atlas Prostate Adenocarcinoma KIAA1683 0.06 0.02 blup 65 0.04 3.2e-05 -8.68 8.9 4.7e-19 0.69 0.09 0.87 FALSE
74 The Cancer Genome Atlas Prostate Adenocarcinoma MYO9B 0.14 0.07 blup 103 0.10 5.0e-11 7.54 -5.7 9.6e-09 -0.05 0.00 1.00 FALSE
75 The Cancer Genome Atlas Soft Tissue Sarcoma KIAA1683 0.07 0.00 blup 64 0.01 4.5e-02 -8.84 10.8 2.2e-27 0.59 0.01 0.68 FALSE
76 The Cancer Genome Atlas Stomach Adenocarcinoma HAUS8 0.06 0.04 blup 55 0.04 1.0e-03 4.92 -6.4 1.6e-10 0.01 0.04 0.41 FALSE
77 The Cancer Genome Atlas Testicular Germ Cell Tumors KIAA1683 0.17 0.06 blup 65 0.06 3.0e-03 -6.60 9.4 3.8e-21 0.68 0.01 0.93 FALSE
78 The Cancer Genome Atlas Thyroid Carcinoma HAUS8 0.04 0.06 lasso 2 0.05 2.2e-05 5.00 -5.5 3.8e-08 -0.01 0.10 0.87 FALSE
79 The Cancer Genome Atlas Thyroid Carcinoma IL12RB1 0.08 0.04 lasso 3 0.05 8.9e-06 3.53 -5.8 5.6e-09 -0.25 0.28 0.55 FALSE
80 The Cancer Genome Atlas Thyroid Carcinoma KIAA1683 0.15 0.09 lasso 6 0.16 5.4e-15 11.10 10.8 3.5e-27 0.75 0.64 0.36 FALSE