Hub : Genes

CLPTM1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.114 0.031 5.8e-05 0.087 0.046 0.084 0.08 0.081 9.3e-11 2.6e-06 2e-10 5.6e-10 4.2e-10
2 GTEx Testis 0.373 0.065 5.7e-07 0.360 NA 0.343 NA 0.360 7.6e-17 NA 6e-16 NA 7.6e-17

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 5.3 8.4 8.7 -2.9 3.0
Bipolar Disorder or Schizophrenia 4.3 10.5 12.0 -3.5 3.0
Depressed Affect (Nagel 2018) 1.6 3.4 4.1 -2.0 1.6
Depression (Nagel 2018) 1.9 2.9 3.3 -1.6 1.8
Intelligence (Savage-Jansen 2018) 0.6 1.8 2.2 1.1 -1.5
Neuroticism (Nagel 2018) 1.4 3.4 3.6 -1.9 1.8
Schizophrenia (2018) 1.6 3.4 4.6 -2.1 1.5
Schizophrenia vs Biploar Disorder 0.0 0.0 0.1 0.3 0.0
Worry (Nagel 2018) 1.7 3.6 4.5 -2.1 1.7
Alzheimer’s Disease (in mother) 15.5 18.2 31.4 -5.6 2.2
Alzheimer’s Disease (in father) 2.3 2.5 4.8 -2.2 0.5
Alzheimer’s Disease (including proxy) 33.6 48.7 85.6 -9.2 3.5
Crohns Disease (2017) 0.0 0.0 0.0 -0.2 0.2
Irritable Bowel Disease (IBD) 0.5 1.3 1.6 1.3 -1.0
Ulcerative Colitis (UC) 1.6 2.9 3.8 2.0 -1.4
Major Depression (MDD) 0.8 1.0 1.3 -1.1 0.8
Reaction Time 0.1 0.1 0.3 -0.5 -0.2
Verbal and Numeric Reasoning (VNR) 1.3 3.1 3.5 1.7 -1.9
Breast Cancer 0.7 1.7 2.3 1.0 -1.5
Ovarian Cancer 0.3 0.5 0.8 -0.9 0.3
Prostate Cancer 0.4 0.5 0.5 -0.7 0.7
Age at First Birth 1.7 2.5 3.5 -1.9 1.2
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.1 0.1 0.2 -0.3 0.4
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.3 0.5 0.9 -1.0 0.0
Mean Putamen Volume 0.6 0.7 1.3 1.1 -0.2
Fasting Glucose 0.1 0.1 0.2 0.4 -0.2
HbA1C 0.3 0.4 0.5 0.5 -0.7
HDL Cholesterol 9.9 16.5 17.4 -4.2 3.9
LDL Cholesterol 0.2 0.3 0.6 -0.8 0.2
Lupus 0.7 1.0 1.8 -1.3 0.5
Neuroticism (2016) 0.8 1.2 1.4 -1.0 1.2
Primary Biliary Cirrhosis 1.9 2.7 3.9 -2.0 1.2
Rheumatoid Arthritis 0.8 1.2 1.9 0.6 -1.4
Schizophrenia (2014) 1.9 4.2 5.2 -2.3 1.8
Triglycerides 5.1 8.4 11.8 -3.4 2.2
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.1 0.2 0.4
Ulcerative Colitis 0.6 0.9 1.0 1.0 -0.9
Blood Eosinophil Count 2.2 16.6 21.5 4.6 -3.4
Blood Platelet Count 0.7 8.4 13.0 -3.6 2.0
Blood Red Count 0.5 4.7 6.7 2.6 -1.7
Blood White Count 1.7 12.7 14.2 -3.4 3.8
Heel T-Score 0.1 0.7 1.3 -0.1 1.2
BMI 1.5 8.4 9.8 3.1 -2.7
Height 1.4 26.7 32.0 5.7 -4.6
Waist Hip Ratio (WHR) 0.7 3.2 3.6 -1.7 1.9
Systolic Blood Pressure 1.1 5.5 8.9 -3.0 1.4
Smoking Status 0.3 0.7 1.1 -0.4 1.1
Allergy or Eczema 1.1 2.9 4.5 2.1 -1.1
Cardiovascular Disease 1.6 5.2 6.8 -2.6 1.9
Hypothyroidism (self reported) 2.4 5.4 6.0 2.5 -2.2
Respiratory disease 1.3 3.0 4.0 2.0 -1.4
Type 2 Diabetes (T2D) (2018) 0.1 0.2 0.3 -0.5 0.3
Lung FEV1/FVC ratio 0.2 1.0 1.9 -0.3 1.4
Lung FVC 0.2 0.9 1.1 -0.8 1.1
Neuroticism 2.3 5.6 6.4 -2.5 2.2
Chronotype (morning person) 0.3 0.7 0.9 -0.6 1.0
Hair Pigment 0.0 0.7 0.9 -0.7 1.0
Tanning 0.1 1.6 2.1 1.0 -1.4
Hand grip strength (left) 0.5 1.2 2.0 1.4 -0.6
Number of treatments/medications taken 0.0 0.0 0.1 -0.2 0.1
Average weekly spirits intake 0.6 0.7 1.4 1.2 -0.3
Sensitivity / hurt feelings 0.9 1.6 1.7 -1.2 1.3
Frequency of depressed mood in last 2 weeks 2.8 3.9 4.2 -1.9 2.0
Hearing difficulty/problems: Yes 0.2 0.3 0.5 0.7 -0.4
Relative age of first facial hair 1.8 3.7 5.2 2.3 -1.5
Other serious medical condition/disability diagnosed by doctor 0.0 0.0 0.0 -0.1 0.1
Ever used hormone-replacement therapy (HRT) 2.3 2.9 3.6 -1.5 1.9
Ever had hysterectomy (womb removed) 0.3 0.3 0.6 -0.8 0.2
Systolic blood pressure, automated reading 0.1 0.3 0.3 -0.6 0.6
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 0.1 -0.3 0.3
Angina 0.3 0.3 0.7 0.8 0.2
Medication for hormone replacement therapy 0.2 0.2 0.5 -0.1 0.7
Vitamin and mineral supplements 0.6 0.8 1.0 0.8 -1.0
Supplements: Zinc 0.0 0.0 0.0 -0.0 0.0
Medication: Co-codamol 0.1 0.1 0.1 0.3 -0.2
Medication: Metformin 0.8 1.1 1.4 0.9 -1.2
Diabetes (father) 0.2 0.2 0.4 0.1 0.7
Diabetes (mother) 0.3 0.4 0.6 0.8 -0.4
Severe depression (siblings) 1.0 1.1 1.7 -0.7 1.3
Pack years adult smoking proportion 0.6 1.0 1.1 -1.0 1.0
Impedance of leg (right) 0.9 4.4 4.8 -2.2 2.0
Leg fat-free mass (left) 3.1 16.7 18.6 4.3 -3.8
Trunk fat percentage 0.7 2.9 4.1 2.0 -1.3
Hand grip strength (right) 0.6 1.6 1.9 1.4 -1.1
Townsend deprivation index at recruitment 0.3 0.4 0.5 0.7 -0.5
Current tobacco smoking 0.4 0.7 1.2 -1.1 0.4
Average weekly fortified wine intake 4.2 4.9 7.7 2.8 -1.4
Maternal smoking around birth 0.1 0.1 0.2 -0.1 0.4
Fed-up feelings 2.9 5.3 7.2 -2.7 1.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 1.2 -1.1 1.0
Relative age voice broke 1.5 2.2 4.1 2.0 -0.6
Taking other prescription medications 0.4 0.5 1.0 1.0 -0.3
Age when periods started (menarche) 1.6 3.8 5.8 2.4 -1.4
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 0.8 -0.9 0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.4 1.4 1.2 -1.1
Tinnitus: Yes, but not now, but have in the past 1.6 1.7 2.2 -1.5 1.1
Qualifications: CSEs or equivalent 0.5 0.6 1.2 -1.1 0.3
Serious illness, injury or assault to yourself 4.0 4.8 4.9 -2.2 2.2
High blood pressure 0.1 0.2 0.3 -0.6 0.3
Hayfever, allergic rhinitis or eczema 0.3 0.6 1.1 1.1 -0.2
Multivitamins +/- minerals 2.1 2.6 3.1 -1.8 1.4
Stomach or abdominal pain in last month 0.6 0.8 0.8 0.9 -0.9
Supplements: Glucosamine 1.0 1.3 1.5 -1.2 1.1
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 1.1 -0.5 1.1
Medication: Atenolol 0.1 0.1 0.2 0.3 -0.4
Medication: Levothyroxine sodium 0.3 0.5 0.5 0.7 -0.7
Sitting height 1.2 8.5 9.1 3.0 -2.8
Chronic bronchitis/emphysema (father) 0.3 0.4 0.5 0.4 -0.7
High blood pressure (mother) 0.1 0.1 0.1 -0.3 0.3
Body mass index (BMI) 1.2 5.2 6.8 2.6 -1.9
Impedance of leg (left) 0.8 3.7 4.5 -2.1 1.7
Leg predicted mass (left) 3.2 17.0 19.0 4.4 -3.9
Trunk fat mass 1.7 7.2 8.9 3.0 -2.4
Waist circumference 1.3 4.6 6.7 2.6 -1.6
Number of incorrect matches in round 0.3 0.4 0.4 -0.6 0.7
Past tobacco smoking 0.3 0.6 1.2 -1.1 -0.0
Alcohol usually taken with meals 0.3 0.5 0.9 0.4 -0.9
Nervous feelings 0.2 0.3 0.5 -0.7 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.2 1.2 -1.1 1.1
Hearing difficulty/problems with background noise 0.4 0.7 1.3 0.4 -1.1
Hair/balding pattern: Pattern 2 0.2 0.3 0.5 0.3 -0.7
Had menopause 0.0 0.0 0.1 0.2 -0.1
Had other major operations 0.1 0.2 0.3 0.6 0.1
Forced vital capacity (FVC) 0.1 0.2 0.4 0.7 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.0 0.1 0.2 0.2 -0.4
Ever unenthusiastic/disinterested for a whole week 1.8 2.1 2.4 -1.4 1.6
Qualifications: None of the above 0.5 1.0 1.4 -1.2 0.8
Financial difficulties in last 2 years 0.5 0.7 0.8 0.9 -0.8
Mouth/teeth dental problems 0.2 0.4 0.6 -0.8 0.3
Heart attack 0.1 0.1 0.2 0.2 0.4
Allergy 0.1 0.3 0.5 -0.7 -0.1
Pain all over the body in last month 0.4 0.4 0.9 0.0 -0.9
Diabetes (self-reported) 0.1 0.2 0.3 0.4 -0.5
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 0.9 1.0 0.4
Medication: Ramipril 0.8 1.1 1.1 -1.1 1.0
Medication: Simvastatin 1.0 1.5 2.2 0.8 -1.5
Fluid intelligence score 1.7 3.5 4.6 1.6 -2.1
Illnesses of siblings 1.5 2.2 3.1 -1.1 1.8
Neuroticism score 2.1 4.3 6.3 -2.5 1.5
Weight 3.3 16.3 19.4 4.4 -3.6
Impedance of arm (right) 0.8 3.6 3.8 -1.8 2.0
Arm fat percentage (right) 0.7 2.9 4.2 2.1 -1.3
Trunk fat-free mass 3.7 21.1 22.4 4.7 -4.5
Hip circumference 3.1 13.3 15.8 4.0 -3.3
Time employed in main current job 0.0 0.0 0.0 -0.0 0.1
Alcohol intake versus 10 years previously 3.7 5.6 6.0 -2.4 2.3
Father’s age at death 0.8 1.1 1.1 1.0 -1.0
Worrier / anxious feelings 4.3 8.0 9.6 -3.1 2.5
Frequency of tiredness / lethargy in last 2 weeks 2.6 4.2 5.3 -1.7 2.3
Falls in the last year 0.3 0.5 0.6 -0.6 0.8
Hair/balding pattern: Pattern 3 0.3 0.4 0.7 -0.9 0.1
Number of live births 0.6 0.8 1.0 1.0 -0.8
Forced expiratory volume in 1-second (FEV1) 0.1 0.4 0.7 0.8 -0.4
Pulse rate 0.1 0.2 0.3 0.4 0.5
Happiness 1.1 1.3 2.2 -0.6 1.5
Noisy workplace 0.7 0.8 1.1 0.8 -1.0
Qualifications: A levels/AS levels or equivalent 0.3 0.6 0.9 0.5 -0.9
Serious illness, injury or assault of a close relative in last 2 years 1.3 1.5 2.0 0.9 -1.4
Mouth/teeth dental problems: Dentures 0.9 1.4 2.5 -0.7 1.6
Asthma 0.4 0.7 1.1 1.1 -0.6
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.2 -0.1 -0.4
Medication: Cholesterol lowering 0.1 0.1 0.1 -0.4 -0.2
Depression (self-reported) 0.7 0.9 0.9 0.9 -1.0
Medication: Lansoprazole 0.1 0.2 0.3 -0.2 0.5
Prospective memory result 4.6 5.7 7.0 -2.6 2.1
Lung cancer (father) 0.3 0.3 0.5 -0.2 0.7
Illnesses of mother 1.5 1.9 2.8 1.7 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.0 0.1 0.1 0.2 0.3
Pulse wave Arterial Stiffness index 2.5 2.9 3.6 -1.5 1.9
Impedance of arm (left) 0.9 4.0 4.1 -2.0 1.9
Arm fat mass (right) 1.8 7.2 9.4 3.1 -2.2
Trunk predicted mass 3.7 20.9 22.2 4.7 -4.4
Standing height 1.7 17.1 17.9 4.2 -4.0
Length of working week for main job 0.3 0.3 0.6 0.0 0.7
Exposure to tobacco smoke at home 4.1 4.6 5.3 -2.3 2.0
Breastfed as a baby 0.0 0.0 0.0 0.0 -0.2
Tense / ‘highly strung’ 1.7 2.9 5.0 -2.2 0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.6 1.6 -1.2 1.2
Hair/balding pattern: Pattern 4 0.3 0.7 1.0 1.0 -0.6
Birth weight of first child 0.6 1.2 1.6 0.9 -1.3
Peak expiratory flow (PEF) 0.3 0.7 0.8 0.7 -0.9
Pulse wave reflection index 1.2 1.5 1.8 -1.4 1.1
Ever highly irritable/argumentative for 2 days 3.3 4.0 4.2 -1.9 2.1
Loud music exposure frequency 3.2 3.5 4.6 -2.1 1.6
Qualifications: O levels/GCSEs or equivalent 0.1 0.1 0.1 0.4 -0.1
Mouth/teeth dental problems: Bleeding gums 1.0 1.3 2.2 1.5 -0.7
Blood clot in the leg (DVT) 0.2 0.2 0.4 -0.2 0.6
Medication: Paracetamol 0.1 0.2 0.3 -0.5 0.3
Headache pain in last month 0.0 0.0 0.0 0.0 -0.0
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 0.5 0.7 -0.4
Glaucoma (self-reported) 2.7 3.1 3.7 1.9 -1.6
Gout (self-reported) 0.2 0.2 0.3 0.4 0.5
Hypothyroidism/myxoedema (self-reported) 1.7 3.3 3.4 1.8 -1.8
Medication: Amlodipine 0.6 0.8 1.2 -0.7 1.1
Medication: Ventolin 100micrograms inhaler 0.1 0.2 0.2 0.5 -0.4
Birth weight 0.6 1.2 1.7 1.3 -0.9
Chronic bronchitis/emphysema (mother) 0.3 0.3 0.5 0.7 -0.4
High blood pressure (siblings) 6.0 8.7 9.8 2.7 -3.1
Forced vital capacity (FVC), Best measure 0.0 0.1 0.1 0.4 0.1
Body fat percentage 0.6 2.5 3.6 1.9 -1.2
Leg fat percentage (right) 0.5 2.0 3.2 1.8 -0.9
Arm fat-free mass (right) 2.7 14.0 14.4 3.8 -3.7
Exposure to tobacco smoke outside home 0.2 0.3 0.4 0.5 -0.6
Comparative body size at age 10 0.1 0.2 0.3 0.5 -0.4
Number of full brothers 0.8 1.0 1.8 0.3 -1.4
Worry too long after embarrassment 0.0 0.0 0.0 -0.2 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 0.9 -0.9 0.2
Wheeze or whistling in the chest in last year 1.3 2.3 2.8 1.7 -1.4
Number of children fathered 2.2 2.5 3.5 1.2 -1.9
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.0 1.3 -1.1 0.9
Age at first live birth 0.2 0.3 0.7 -0.8 0.2
Pulse wave peak to peak time 3.3 3.8 4.4 1.8 -2.1
Health satisfaction 6.3 8.2 9.2 -2.7 3.0
Shortness of breath walking on level ground 1.8 2.1 2.9 -1.2 1.7
Qualifications: College or University degree 0.1 0.2 0.3 0.5 -0.3
Eye problems/disorders: None of the above 0.5 0.5 1.0 -0.3 1.0
Mouth/teeth dental problems: Loose teeth 0.4 0.4 0.8 0.9 -0.3
Emphysema/chronic bronchitis 0.5 0.6 0.9 0.9 -0.5
Medication for pain relief, constipation, heartburn 0.0 0.1 0.1 0.3 -0.2
Neck or shoulder pain in last month 0.7 1.0 1.6 -0.5 1.3
Medication: Blood pressure 1.0 1.7 2.3 -1.5 1.1
Angina (self-reported) 0.4 0.5 1.0 1.0 0.1
Migraine (self-reported) 0.2 0.2 0.4 -0.6 0.2
Medication: Ibuprofen 0.2 0.2 0.3 0.3 -0.6
Medication: Allopurinol 0.3 0.4 0.7 0.9 0.2
Medication: Omeprazole 1.9 2.2 2.3 1.5 -1.5
Medication: Seretide 50 evohaler 0.4 0.5 0.5 0.7 -0.7
Mean time to correctly identify matches 0.0 0.0 0.0 -0.1 -0.0
Heart disease (mother) 1.3 1.5 2.4 1.6 -0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.1 0.3 -0.3
Whole body fat mass 1.5 6.1 7.7 2.8 -2.1
Leg fat mass (right) 1.5 5.7 7.6 2.8 -2.0
Arm predicted mass (right) 2.5 13.0 13.2 3.6 -3.6
Pulse rate, automated reading 0.1 0.5 0.6 -0.8 0.5
Alcohol intake frequency. 1.2 2.8 3.1 -1.8 1.6
Comparative height size at age 10 1.4 8.0 9.0 3.0 -2.6
Number of full sisters 0.5 0.6 0.6 0.7 -0.8
Suffer from ‘nerves’ 0.1 0.2 0.4 -0.6 -0.1
Overall health rating 0.8 1.6 2.1 -1.1 1.5
Chest pain or discomfort 0.3 0.5 0.9 1.0 -0.1
Had major operations 0.5 0.6 1.0 -1.0 0.4
Age at last live birth 0.3 0.5 0.8 -0.9 0.5
Family relationship satisfaction 0.2 0.2 0.4 0.6 -0.1
Leg pain on walking 0.1 0.1 0.2 -0.0 0.4
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.2 0.2 -0.3 0.5
Commuting to job workplace: Car/motor vehicle 2.2 2.5 2.7 1.6 -1.5
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 1.3 -0.6 1.2
Medication: Aspirin 0.6 0.7 0.9 -0.8 0.9
Supplements: Vitamin C 0.1 0.2 0.2 0.4 0.4
Knee pain experienced in last month 0.1 0.1 0.2 -0.1 0.5
Hypertension (Self-reported) 0.1 0.3 0.6 -0.7 0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.2 -0.4 0.2
Illnesses of father: Heart disease 1.5 2.1 2.4 1.4 -1.6
Illnesses of siblings: Diabetes 0.2 0.2 0.4 -0.4 -0.6
Smoking status: Previous 0.3 0.4 0.8 0.9 0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.7 1.6 1.8 1.1 -1.4
Whole body fat-free mass 3.6 20.4 21.7 4.7 -4.4
Leg fat-free mass (right) 3.2 17.3 18.7 4.3 -4.0
Arm fat percentage (left) 0.6 2.6 3.6 1.9 -1.2
Average weekly red wine intake 0.8 1.2 1.6 1.3 -0.9
Handedness (chirality/laterality): Left-handed 2.6 3.1 3.7 -1.9 1.6
Mood swings 2.2 3.9 5.6 -2.4 1.5
Loneliness, isolation 0.0 0.0 0.0 0.0 -0.2
Long-standing illness, disability or infirmity 0.0 0.1 0.1 0.3 0.0
Ever had bowel cancer screening 1.6 1.8 2.0 1.4 -1.3
Diabetes diagnosed by doctor 0.2 0.4 0.5 0.7 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.7 0.8 0.8 -0.9
Friendships satisfaction 2.2 2.8 4.5 -1.0 2.1
Qualifications: nursing, teaching 0.1 0.1 0.2 -0.4 0.3
Commuting to job workplace: Walk 0.3 0.3 0.6 0.8 -0.2
Eye problems/disorders: Cataract 0.2 0.3 0.3 0.5 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.8 1.2 2.4 0.1 -1.6
Medication for cholesterol 0.1 0.1 0.2 0.4 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 0.9 -0.5 0.9
Back pain experienced in last month 0.1 0.1 0.1 -0.3 0.4
Mineral and other dietary supplements 1.5 2.0 2.6 1.6 -1.2
Breast cancer (self-reported) 0.8 0.9 1.1 -0.9 1.1
Asthma (self-reported) 0.5 1.0 1.4 1.2 -0.7
Osteoporosis (self-reported) 0.0 0.0 0.0 0.2 0.1
Osteoarthritis (self-reported) 0.8 1.0 1.5 -0.8 1.2
Medication: Aspirin 0.4 0.5 0.7 -0.6 0.9
Medication: Gliclazide 2.2 2.4 3.0 1.7 -1.4
Illnesses of father: None of the above (group 1) 1.3 1.6 2.8 -0.7 1.7
Smoking status: Current 0.5 0.8 1.3 -1.1 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.0 0.1 0.1 -0.1 0.4
Whole body water mass 3.4 19.2 20.4 4.5 -4.2
Leg predicted mass (right) 3.2 16.9 18.5 4.3 -3.9
Arm fat mass (left) 1.5 6.1 7.8 2.8 -2.1
Number of self-reported non-cancer illnesses 0.0 0.0 0.0 0.1 -0.1
Average weekly champagne plus white wine intake 0.1 0.1 0.2 -0.5 -0.2
Miserableness 4.6 8.0 9.9 -3.1 2.5
Guilty feelings 0.4 0.6 0.9 -1.0 0.4
Wears glasses or contact lenses 4.5 5.2 5.2 -2.3 2.3
Ever taken oral contraceptive pill 0.5 0.5 0.6 0.7 -0.7
Hearing aid user 0.2 0.2 0.4 0.2 0.6
Mother’s age at death 1.2 1.5 1.6 1.2 -1.3
Financial situation satisfaction 1.9 2.3 2.6 -1.4 1.6
Tinnitus: Yes, now most or all of the time 3.9 4.5 5.1 2.0 -2.3
Commuting to job workplace: Public transport 0.1 0.2 0.3 0.0 -0.6
Eye problems/disorders: Glaucoma 1.0 1.2 1.2 1.1 -1.1
Medication: Blood pressure 0.3 0.6 1.1 0.2 -1.0
Pain type(s) experienced in last month: Hip pain 0.7 0.9 1.5 0.6 -1.2
Supplements: Fish oil (including cod liver oil) 4.2 5.5 7.7 -2.8 1.8
High cholesterol (Self-reported) 1.8 3.1 4.5 -2.1 1.3
Medication: Bendroflumethiazide 0.1 0.2 0.3 -0.3 -0.5
Medication: Paracetamol 0.2 0.3 0.4 -0.7 0.3
Medication: Lisinopril 0.3 0.4 0.7 0.4 -0.8
Medication: Atorvastatin 0.9 1.1 1.4 -0.9 1.2
Illnesses of father: High blood pressure 4.6 5.7 8.0 1.8 -2.8
Alcohol drinker status: Never 0.4 0.5 0.9 -1.0 -0.3
Ever smoked 0.1 0.2 0.2 0.4 0.5
Basal metabolic rate 3.6 20.1 21.9 4.7 -4.3
Leg fat percentage (left) 0.8 2.8 4.0 2.0 -1.2
Arm fat-free mass (left) 3.1 16.0 17.2 4.2 -3.8
Number of operations (self-reported) 0.3 0.4 0.5 0.7 -0.5
Average weekly beer plus cider intake 0.7 1.0 1.3 -1.1 0.8
Irritability 0.9 1.5 1.6 -1.3 1.2
Risk taking 0.5 0.8 1.1 0.7 -1.0
Ever had prostate specific antigen (PSA) test 1.3 1.5 2.0 -1.0 1.4
Fractured/broken bones in last 5 years 0.7 0.9 1.3 -1.1 0.7
Age started oral contraceptive pill 0.2 0.3 0.4 -0.7 0.3
Diastolic blood pressure, automated reading 0.0 0.1 0.1 -0.2 0.4
Ever depressed for a whole week 1.1 1.4 1.7 -1.1 1.3
Unable to work because of sickness or disability 0.2 0.2 0.2 -0.5 0.4
Commuting to job workplace: Cycle 0.1 0.1 0.2 -0.5 0.1
Myopia 0.6 0.9 1.2 -0.7 1.1
Vascular/heart problems diagnosed by doctor 0.0 0.0 0.0 -0.1 0.0
Cholesterol lowering medication 0.0 0.0 0.1 -0.0 -0.3
Medication: Omeprazole (e.g. Zanprol) 2.6 3.2 4.1 2.0 -1.5
Pain experienced in last month 0.0 0.0 0.0 -0.1 -0.2
Supplements: Calcium 0.0 0.1 0.1 -0.3 0.2
Basal cell carcinoma (self-reported) 1.5 1.7 2.1 -1.5 1.2
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.1 0.3 0.3
Deep venous thrombosis (DVT) (self-reported) 0.1 0.2 0.3 -0.1 0.6
Heart disease (siblings) 2.8 3.5 3.5 1.9 -1.9
Alcohol drinker status: Previous 1.4 1.6 1.7 -1.3 1.2
Pack years of smoking 0.6 0.9 1.0 -0.9 1.0
Impedance of whole body 1.0 5.1 5.8 -2.4 2.1
Leg fat mass (left) 1.7 6.5 8.4 2.9 -2.2
Arm predicted mass (left) 3.5 17.6 19.1 4.4 -4.0