Hub : Genes

ZSCAN29

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2160	0.0550	0.0e+00	0.282	0.259	0.263	0.269	0.272	1.8e-34	2.0e-31	7.2e-32	1.2e-32	4.7e-33
2	GTEx	Adipose Subcutaneous	0.2740	0.0730	1.3e-09	0.109	NA	0.137	NA	0.134	3.5e-09	NA	2.6e-11	NA	4.8e-11
3	GTEx	Adipose Visceral Omentum	0.0720	0.0370	7.5e-04	0.044	NA	0.040	NA	0.045	2.5e-03	NA	3.8e-03	NA	2.3e-03
4	GTEx	Brain Caudate basal ganglia	0.2570	0.1030	9.8e-05	0.147	NA	0.145	NA	0.140	5.2e-05	NA	5.8e-05	NA	7.9e-05
5	GTEx	Brain Frontal Cortex BA9	0.1837	0.0928	1.6e-03	-0.002	NA	0.140	NA	0.030	3.6e-01	NA	1.5e-04	NA	5.4e-02
6	GTEx	Brain Nucleus accumbens basal ganglia	0.1480	0.0840	7.4e-03	0.040	NA	0.070	NA	0.039	3.1e-02	NA	6.1e-03	NA	3.3e-02
7	GTEx	Breast Mammary Tissue	0.1140	0.0430	2.7e-06	0.157	NA	0.102	NA	0.121	1.8e-08	NA	6.5e-06	NA	9.3e-07
8	GTEx	Breast Mammary Tissue (Male)	0.0864	0.0697	1.1e-01	0.044	NA	-0.012	NA	0.011	3.5e-02	NA	7.7e-01	NA	1.7e-01
9	GTEx	Cells Transformed fibroblasts	0.1110	0.0500	1.3e-04	0.074	NA	0.039	NA	0.059	3.2e-06	NA	6.2e-04	NA	3.2e-05
10	GTEx	Colon Sigmoid	0.1320	0.0780	1.5e-03	0.055	NA	0.049	NA	0.062	5.1e-03	NA	8.0e-03	NA	3.2e-03
11	GTEx	Colon Transverse	0.0630	0.0390	9.6e-03	0.041	NA	0.029	NA	0.039	5.0e-03	NA	1.5e-02	NA	6.1e-03
12	GTEx	Esophagus Muscularis	0.1440	0.0580	1.5e-07	0.113	NA	0.134	NA	0.126	2.2e-07	NA	1.7e-08	NA	4.6e-08
13	GTEx	Heart Atrial Appendage	0.1390	0.0690	7.0e-04	0.086	NA	0.079	NA	0.071	1.1e-04	NA	2.0e-04	NA	4.3e-04
14	GTEx	Heart Left Ventricle	0.1108	0.0648	8.5e-03	0.063	NA	0.038	NA	0.048	3.0e-04	NA	4.1e-03	NA	1.5e-03
15	GTEx	Lung	0.0644	0.0391	1.5e-03	0.053	NA	0.038	NA	0.039	6.9e-05	NA	6.9e-04	NA	5.3e-04
16	GTEx	Muscle Skeletal	0.1099	0.0430	5.0e-09	0.107	NA	0.091	NA	0.104	1.3e-10	NA	3.3e-09	NA	2.3e-10
17	GTEx	Nerve Tibial	0.3241	0.0718	2.0e-11	0.177	NA	0.146	NA	0.171	1.5e-12	NA	1.6e-10	NA	3.5e-12
18	GTEx	Pancreas	0.1140	0.0690	5.5e-03	0.043	NA	0.009	NA	0.030	6.4e-03	NA	1.3e-01	NA	1.9e-02
19	GTEx	Prostate	0.1630	0.0710	9.3e-04	0.165	NA	0.048	NA	0.125	6.3e-05	NA	2.4e-02	NA	4.9e-04
20	GTEx	Skin Not Sun Exposed Suprapubic	0.0900	0.0580	1.1e-03	0.061	NA	0.048	NA	0.060	3.0e-04	NA	1.2e-03	NA	3.2e-04
21	GTEx	Skin Sun Exposed Lower leg	0.0560	0.0310	2.5e-04	0.035	NA	0.042	NA	0.034	6.4e-04	NA	2.1e-04	NA	7.3e-04
22	GTEx	Spleen	0.2340	0.1100	1.9e-03	0.181	NA	0.059	NA	0.135	2.2e-05	NA	1.3e-02	NA	2.5e-04
23	GTEx	Testis	0.4650	0.0950	7.2e-10	0.169	NA	0.211	NA	0.202	5.7e-08	NA	9.6e-10	NA	2.3e-09
24	GTEx	Thyroid	0.1730	0.0580	2.5e-13	0.155	NA	0.197	NA	0.190	6.4e-12	NA	5.2e-15	NA	1.6e-14
25	METSIM	Adipose	0.0356	0.0165	6.9e-06	0.030	0.036	0.031	0.034	0.039	1.9e-05	3.1e-06	1.5e-05	5.7e-06	1.6e-06
26	NTR	Blood	0.0305	0.0138	1.5e-08	0.032	0.019	0.021	0.019	0.027	1.1e-10	5.3e-07	2.3e-07	7.6e-07	2.5e-09
27	TCGA	Kidney Renal Clear Cell Carcinoma	0.0553	0.0373	1.3e-04	0.051	0.045	0.046	NA	0.050	1.9e-06	7.8e-06	6.1e-06	NA	2.6e-06
28	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0630	0.0520	8.4e-03	0.016	0.026	0.021	NA	0.020	4.0e-02	1.3e-02	2.3e-02	NA	2.5e-02
29	TCGA	Testicular Germ Cell Tumors	0.1010	0.0710	8.6e-03	0.078	0.053	0.051	NA	0.067	1.0e-03	5.8e-03	6.8e-03	NA	2.2e-03
30	TCGA	Thyroid Carcinoma	0.0550	0.0410	5.3e-04	0.052	0.035	0.044	NA	0.046	8.1e-06	2.2e-04	3.5e-05	NA	2.5e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30
Bipolar Disorder (2018)	0.1	0.2	2.5	-0.7	-0.9	0.4	-0.1	-0.7	-0.0	0.2	0.0	1.6	0.6	0.3	0.2	0.0	0.0	-0.0	0.4	-0.3	0.0	0.2	0.2	0.3	0.3	0.0	0.2	0.4	-0.0	-0.1	0.1	-0.1	0.6
Bipolar Disorder or Schizophrenia	2.6	6.4	10.7	-3.3	2.0	3.0	-2.5	-2.8	-2.7	2.5	2.0	3.0	3.1	2.7	2.7	2.1	2.1	2.3	2.9	2.0	0.0	2.2	2.6	2.8	2.7	1.9	2.7	2.9	2.0	2.2	2.5	2.0	3.3
Depressed Affect (Nagel 2018)	3.1	6.5	9.1	-2.2	2.9	2.4	-2.8	-1.5	-2.5	3.0	2.9	2.7	1.7	2.7	2.7	1.9	2.9	2.8	2.6	2.8	3.0	2.9	2.5	2.3	1.9	2.4	2.6	2.7	2.8	2.8	2.6	2.8	1.2
Depression (Nagel 2018)	4.1	6.1	8.7	-2.7	2.5	2.5	-2.5	-1.3	-1.8	2.9	2.7	2.9	2.3	2.8	2.8	1.5	2.7	2.6	2.7	2.4	2.8	2.7	2.2	2.3	2.2	2.1	2.7	2.8	2.4	2.5	2.6	2.4	1.8
Intelligence (Savage-Jansen 2018)	2.1	6.4	11.7	3.0	-2.2	-2.8	1.4	2.6	3.4	-2.2	-2.1	-2.7	-2.6	-2.4	-2.7	-3.1	-2.2	-2.5	-2.5	-2.1	-2.0	-2.1	-2.8	-2.9	-3.0	-2.7	-2.8	-2.7	-2.1	-2.2	-2.4	-2.1	-2.4
Neuroticism (Nagel 2018)	3.8	8.9	14.1	-1.7	3.6	2.3	-3.5	-1.9	-2.5	3.6	3.6	3.4	1.9	3.1	3.1	2.3	3.4	3.4	2.7	3.8	3.7	3.6	2.6	2.3	2.1	2.4	2.7	2.6	3.5	3.6	3.2	3.6	1.5
Schizophrenia (2018)	4.5	9.4	13.7	-3.7	3.3	3.6	-3.3	-3.2	-3.6	3.0	2.6	2.5	3.5	3.2	3.4	2.7	2.6	3.0	3.4	2.9	0.0	2.6	3.2	3.3	3.2	2.1	3.4	3.5	2.6	2.9	3.1	2.6	3.7
Schizophrenia vs Biploar Disorder	0.4	0.6	1.7	-0.6	1.2	0.6	-0.6	-0.8	-1.3	0.7	0.7	-0.2	0.7	0.8	0.8	0.9	0.9	0.8	0.8	0.9	0.0	0.6	1.2	0.6	0.6	0.5	0.7	0.3	0.7	0.7	0.7	0.7	0.9
Worry (Nagel 2018)	4.1	8.7	15.4	-1.5	3.7	2.1	-3.4	-1.4	-2.3	3.5	3.6	3.4	1.9	3.0	3.1	2.1	3.5	3.5	2.5	3.9	3.7	3.7	2.4	2.1	1.8	1.8	2.6	2.2	3.7	3.7	3.2	3.8	1.6
Alzheimer’s Disease (in mother)	1.7	2.0	5.2	-1.2	1.1	1.3	-1.4	-2.3	-2.0	1.2	1.3	1.4	1.7	1.2	1.4	1.4	1.0	1.4	1.2	1.4	1.2	1.3	1.2	1.5	1.4	1.1	1.6	1.5	1.3	1.4	1.3	1.4	1.7
Alzheimer’s Disease (in father)	0.3	0.3	2.5	0.1	-0.7	-0.1	1.6	0.3	0.7	-0.5	-0.6	-1.0	-0.5	-0.1	-0.4	0.6	-0.8	-0.5	0.1	-0.4	-0.7	-0.8	0.3	0.2	0.5	-0.5	-0.3	-0.6	-0.6	-0.3	-0.2	-0.4	-0.5
Alzheimer’s Disease (including proxy)	1.3	2.0	4.6	-1.4	1.1	1.3	-0.4	-2.2	-1.6	1.2	1.1	0.8	1.5	1.4	1.5	2.1	0.7	1.3	1.5	1.3	1.0	0.9	1.7	1.9	2.0	1.1	1.5	1.3	1.2	1.4	1.4	1.3	1.4
Crohns Disease (2017)	0.4	1.0	4.0	1.4	-0.5	-1.4	-0.1	0.3	0.5	-0.7	-0.5	-0.4	-1.7	-1.0	-1.0	-0.5	-0.3	-0.6	-1.1	-0.5	-0.4	-0.5	-1.0	-1.7	-0.7	-1.5	-1.0	-1.6	-0.5	-0.6	-0.9	-0.6	-2.0
Irritable Bowel Disease (IBD)	0.3	0.6	2.7	0.3	0.5	-0.3	-1.5	-0.7	-1.6	0.6	0.8	1.2	-0.5	0.3	0.4	1.6	1.0	0.8	0.2	0.6	0.7	0.9	0.7	-0.2	0.7	-0.3	0.2	-0.2	0.8	0.6	0.3	0.7	-0.9
Ulcerative Colitis (UC)	1.3	2.4	7.2	-0.9	1.2	0.8	-2.3	-1.6	-2.7	1.4	1.7	2.1	0.8	1.2	1.4	2.7	1.7	1.7	1.2	1.4	1.4	1.8	1.8	1.2	1.7	0.7	1.1	1.1	1.5	1.4	1.3	1.4	0.6
Major Depression (MDD)	2.6	3.1	6.3	-2.1	1.8	2.2	-2.1	-1.6	-1.5	1.7	1.4	2.3	1.9	1.9	1.9	1.3	1.0	1.6	2.2	1.4	1.3	1.4	1.6	2.4	2.3	0.5	2.1	2.5	1.3	1.4	1.6	1.3	1.9
Reaction Time	2.7	5.1	9.4	2.1	-1.6	-2.2	2.2	1.9	1.8	-2.4	-2.4	-3.1	-2.7	-2.4	-2.4	-1.8	-2.1	-2.3	-2.0	-2.2	-2.3	-2.5	-1.8	-2.5	-2.1	-1.3	-2.4	-2.1	-2.5	-2.5	-2.4	-2.5	-2.6
Verbal and Numeric Reasoning (VNR)	0.4	1.1	3.7	1.6	-0.4	-1.3	0.2	1.6	1.9	-0.7	-0.6	-0.9	-1.2	-0.9	-1.2	-1.4	-0.4	-0.9	-1.1	-0.4	-0.6	-0.6	-1.4	-1.2	-1.5	-0.8	-1.3	-1.0	-0.6	-0.6	-0.8	-0.6	-1.0
Breast Cancer	4.5	10.8	15.9	3.6	-3.2	-3.6	3.9	2.7	3.8	-3.4	-3.0	-3.6	-2.9	-3.3	-3.5	-3.3	-3.2	-3.3	-3.4	-2.9	-3.2	-3.1	-3.4	-3.4	-3.5	-2.1	-3.5	-4.0	-2.9	-3.1	-3.3	-3.0	-2.4
Ovarian Cancer	6.7	8.9	12.0	3.1	-3.4	-3.4	2.4	2.7	3.5	-2.8	-2.6	-2.1	-3.4	-3.1	-3.2	-2.8	-2.6	-3.0	-3.2	-3.0	-2.6	-2.6	-3.0	-3.2	-3.2	-2.2	-3.4	-3.4	-2.7	-2.8	-3.2	-2.7	-3.3
Prostate Cancer	0.7	0.9	2.7	-1.3	1.1	1.5	-0.8	-1.0	-0.9	0.7	0.4	0.5	1.2	0.8	0.7	1.4	0.4	0.8	1.0	0.6	0.5	0.4	1.0	1.6	1.6	0.9	1.0	0.8	0.4	0.5	0.9	0.4	1.2
Age at First Birth	5.8	8.4	17.8	3.6	-3.1	-3.4	2.8	3.5	3.3	-2.2	-1.7	-1.7	-3.2	-2.9	-2.9	-3.5	-1.7	-2.7	-3.7	-2.2	-1.7	-1.7	-3.2	-4.0	-4.2	-2.7	-3.3	-3.7	-1.8	-2.0	-2.5	-1.8	-3.1
Bipolar Disorder (2011)	0.2	0.2	2.7	-0.5	-0.6	0.4	0.6	0.7	0.2	0.3	0.1	1.6	0.3	0.2	0.2	0.4	0.0	-0.0	0.3	-0.2	0.0	0.3	0.1	0.5	0.5	0.9	0.1	0.3	-0.0	0.0	0.1	-0.1	0.2
Body Mass Index (BMI) (2010)	1.1	1.6	6.2	-2.1	-0.1	1.5	0.6	-1.9	-0.7	-0.0	-0.6	0.6	1.4	0.7	0.5	1.8	-0.9	0.1	1.6	-0.6	-0.7	-0.6	1.5	2.1	2.5	2.0	1.1	1.9	-0.7	-0.5	0.3	-0.7	1.5
Coronary Artery Disease (CAD)	1.2	1.5	2.8	-0.9	0.6	1.4	-1.1	-0.3	-1.2	1.5	1.4	1.6	1.0	1.4	1.3	1.6	1.3	1.4	1.3	1.0	0.0	1.7	1.4	1.1	0.8	1.6	1.2	0.8	1.5	1.3	1.1	1.4	0.7
Crohns Disease (2012)	2.2	3.6	7.1	2.5	-1.6	-2.3	2.0	2.3	2.4	-1.6	-1.4	-1.1	-2.5	-1.9	-2.0	-1.9	-1.4	-1.7	-2.1	-1.4	0.0	-1.4	-2.0	-2.4	-1.9	-0.8	-2.1	-2.3	-1.4	-1.5	-1.9	-1.4	-2.7
Mean Putamen Volume	0.4	0.4	1.3	1.1	-0.7	-1.0	0.3	1.0	1.0	-0.5	-0.4	-0.0	-0.6	-0.6	-0.8	-0.5	-0.4	-0.4	-0.9	-0.4	0.0	-0.3	-0.9	-0.5	-0.8	-0.8	-0.8	-0.8	-0.3	-0.3	-0.5	-0.3	-0.6
Fasting Glucose	0.5	0.6	2.3	0.2	-1.5	-0.5	1.0	-0.0	0.4	-0.6	-1.1	-0.2	-0.6	-0.6	-0.8	0.3	-0.7	-1.0	-0.1	-1.4	-0.9	-1.2	0.2	-0.4	0.3	0.5	-0.6	0.2	-1.3	-1.2	-0.9	-1.2	-0.7
HbA1C	4.8	5.3	9.4	-2.3	2.2	2.1	-0.3	-0.3	-1.1	2.4	2.6	2.5	2.5	2.7	2.4	2.4	2.4	2.6	2.4	2.3	2.1	2.1	2.5	2.4	2.4	3.1	2.3	2.5	2.4	2.4	2.5	2.3	2.4
HDL Cholesterol	0.9	1.5	4.3	-1.6	1.4	1.3	-0.8	-2.1	-1.5	0.7	0.7	0.1	1.5	1.1	1.0	1.7	0.6	0.8	1.5	0.9	0.0	0.5	1.6	2.0	1.9	0.2	1.3	1.5	0.5	0.7	1.1	0.6	2.0
LDL Cholesterol	0.9	1.4	2.5	-1.5	1.2	1.6	-0.8	-1.2	-0.9	1.4	1.0	0.7	1.3	1.5	1.2	0.6	1.0	1.1	1.3	1.3	0.0	0.9	1.5	0.9	0.8	1.1	1.4	1.0	1.1	1.4	1.5	1.2	1.2
Lupus	5.4	8.2	15.0	3.7	-2.4	-3.7	2.0	2.4	3.5	-2.5	-1.8	-2.0	-3.8	-3.2	-2.8	-3.1	-1.9	-2.5	-3.5	-2.0	-1.9	-2.0	-3.9	-3.4	-3.0	-3.2	-3.2	-3.2	-1.9	-2.2	-2.9	-1.9	-3.9
Neuroticism (2016)	1.4	2.1	4.1	-0.3	1.7	0.6	-1.9	-1.4	-1.3	1.6	1.8	1.9	0.4	1.3	1.4	1.2	1.6	1.7	1.0	2.0	1.6	1.9	1.2	1.1	1.0	0.9	0.9	0.9	1.9	1.9	1.4	2.0	0.4
Primary Biliary Cirrhosis	1.2	1.6	3.5	0.5	-0.8	-0.9	1.6	0.1	1.4	-1.5	-1.8	-1.9	-1.4	-1.1	-1.2	-0.1	-1.8	-1.4	-0.4	-1.4	-1.7	-1.9	-0.7	-0.4	0.5	-0.5	-1.0	-0.7	-1.8	-1.7	-1.3	-1.7	-1.4
Rheumatoid Arthritis	0.2	0.3	1.0	-0.4	0.4	0.3	-0.9	-1.0	-0.9	0.7	0.8	0.3	0.3	0.5	0.7	0.1	0.7	0.5	0.4	0.7	0.0	0.7	0.3	-0.3	0.0	-0.6	0.4	0.4	0.6	0.6	0.5	0.7	0.4
Schizophrenia (2014)	5.2	11.5	17.6	-4.2	3.6	4.0	-3.9	-3.6	-4.1	3.5	3.0	2.7	3.9	3.7	3.7	2.6	3.2	3.2	3.9	3.1	0.0	2.9	3.9	3.6	3.0	1.8	3.7	3.7	2.9	3.1	3.5	2.9	4.1
Triglycerides	2.1	3.5	11.0	2.8	-1.3	-2.5	0.2	2.8	2.3	-0.6	-0.2	-0.1	-2.5	-1.5	-1.4	-3.0	-0.1	-0.8	-2.4	-0.4	0.0	-0.2	-2.5	-3.3	-3.1	-1.9	-1.8	-2.3	-0.0	-0.2	-1.1	-0.0	-3.1
Type 2 Diabetes (T2D) (2012)	0.2	0.2	2.2	-0.2	0.4	-0.2	-0.1	-0.9	0.4	0.3	-0.0	-0.1	0.5	0.1	0.2	0.2	-0.1	0.2	0.4	0.2	0.0	-0.0	-0.1	0.5	0.6	1.5	0.3	0.3	0.2	-0.1	0.2	0.2	0.7
Ulcerative Colitis	0.6	0.9	6.0	-0.5	0.7	0.2	-0.8	-0.5	-1.5	0.5	0.8	1.7	0.1	0.5	0.7	2.5	0.6	0.9	0.9	0.6	0.0	0.9	1.2	1.4	1.8	1.0	0.4	0.7	0.6	0.6	0.6	0.6	0.1
Blood Eosinophil Count	4.2	32.7	56.7	4.1	-5.8	-4.8	6.4	2.0	5.6	-6.7	-7.1	-5.7	-5.0	-6.1	-6.3	-3.7	-7.5	-6.5	-4.8	-6.7	-6.9	-7.0	-4.9	-3.9	-2.9	-4.0	-5.4	-4.7	-7.0	-7.0	-6.5	-7.1	-4.6
Blood Platelet Count	0.7	8.4	41.0	5.2	0.5	-4.1	-0.7	6.4	3.4	0.1	1.3	-0.1	-3.5	-1.4	-1.5	-3.9	1.8	0.2	-3.0	1.1	1.5	1.0	-3.4	-4.6	-5.1	-2.7	-2.6	-2.4	1.6	1.1	-1.0	1.5	-4.3
Blood Red Count	0.8	7.7	39.4	-4.1	1.5	3.7	-3.1	-6.3	-3.1	1.4	0.6	1.8	4.2	2.1	2.1	3.1	0.7	1.7	3.1	0.9	0.8	0.6	2.7	3.3	4.4	-0.3	3.1	3.3	0.6	0.8	2.0	0.6	4.5
Blood White Count	0.3	2.2	4.2	-0.9	2.0	0.9	-1.5	-1.7	-1.6	1.5	1.7	0.2	0.9	1.5	1.4	1.6	1.5	2.1	1.5	1.9	1.8	1.6	1.6	1.0	1.0	1.3	1.4	1.0	1.8	1.8	1.4	1.8	0.6
Heel T-Score	0.6	4.4	9.2	2.5	-2.7	-2.5	1.9	2.1	3.0	-1.6	-1.3	-0.6	-2.3	-2.0	-2.2	-2.5	-1.2	-1.9	-2.3	-1.7	-1.4	-1.3	-2.5	-3.0	-2.9	-2.0	-2.3	-2.4	-1.3	-1.4	-1.9	-1.2	-2.4
BMI	1.2	6.8	22.5	-3.8	1.9	3.4	-2.4	-4.7	-2.7	2.1	1.6	1.4	3.2	2.8	2.7	2.4	1.6	2.3	3.1	1.8	1.7	1.5	2.7	2.6	3.3	1.2	3.3	3.4	1.7	1.8	2.5	1.7	3.1
Height	0.1	2.1	7.3	1.6	-2.7	-1.9	0.5	-0.8	0.5	-1.2	-1.2	0.3	-1.0	-1.4	-1.5	-1.3	-0.8	-1.9	-1.2	-1.8	-1.6	-1.1	-0.9	-1.4	-1.6	-2.5	-1.8	-1.2	-1.4	-1.5	-1.4	-1.4	-0.3
Waist Hip Ratio (WHR)	0.1	0.5	1.1	0.1	0.5	0.1	-1.0	-0.8	-0.3	0.8	1.0	0.9	0.2	0.5	0.7	-0.8	0.7	0.7	0.1	0.8	1.1	0.9	-0.2	-0.5	-0.6	0.2	0.5	0.2	1.0	0.9	0.5	1.0	-0.0
Systolic Blood Pressure	1.1	5.4	9.6	3.1	-2.5	-2.8	2.0	1.6	2.4	-2.2	-1.7	-1.7	-3.1	-2.4	-2.6	-2.3	-1.9	-2.3	-2.6	-2.0	-1.9	-1.7	-2.5	-2.2	-2.9	-1.3	-2.8	-2.9	-1.8	-1.9	-2.4	-1.8	-3.1
Smoking Status	0.3	0.8	1.5	-1.2	0.6	1.2	-0.7	-0.8	-1.2	0.9	0.9	0.4	1.0	0.9	1.1	0.4	1.2	1.0	0.8	0.9	1.0	0.9	0.8	0.1	0.5	0.4	1.1	0.6	1.0	1.0	1.0	1.0	0.9
Allergy or Eczema	0.2	0.5	2.5	-1.0	0.9	0.7	-0.8	-1.6	-1.0	0.4	0.3	0.3	0.4	0.5	0.6	1.3	0.3	0.5	0.5	0.5	0.4	0.3	0.7	1.2	1.5	-0.2	0.6	0.4	0.3	0.3	0.5	0.3	0.5
Cardiovascular Disease	0.3	0.9	4.2	1.0	0.6	-0.7	-0.6	0.6	0.1	0.2	0.5	-1.3	-1.1	0.1	-0.1	-1.8	0.5	0.3	-0.7	0.8	0.7	0.2	-0.6	-2.1	-2.0	-1.4	-0.2	-0.4	0.7	0.7	0.1	0.7	-1.5
Hypothyroidism (self reported)	1.1	2.5	4.1	-1.0	1.9	1.3	-1.3	-0.1	-0.9	1.8	1.9	1.8	1.3	1.6	1.8	1.2	2.0	1.9	1.3	2.0	2.0	1.9	0.9	1.4	1.3	0.8	1.6	1.7	2.0	2.0	1.8	2.0	1.0
Respiratory disease	0.1	0.2	0.7	0.4	-0.2	-0.5	-0.4	-0.3	-0.2	0.1	0.2	0.8	-0.6	-0.3	-0.0	-0.5	0.4	0.1	-0.7	0.2	0.3	0.3	-0.6	-0.8	-0.6	-0.1	-0.2	-0.1	0.4	0.2	-0.1	0.4	-0.7
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.5	-1.0	-0.2	0.6	0.5	-1.2	-0.6	-0.1	-0.3	-0.3	0.3	0.2	0.3	-0.5	-0.5	-0.2	0.4	-0.2	-0.4	-0.4	0.4	-0.1	-0.1	0.4	0.3	0.2	-0.2	-0.2	0.1	-0.3	0.5
Lung FEV1/FVC ratio	0.1	0.3	4.2	0.2	-0.5	0.1	-0.1	2.0	0.5	0.1	0.1	1.2	0.1	0.1	-0.1	-0.7	0.1	-0.0	-0.2	-0.1	0.0	0.3	-0.2	-0.2	-0.4	-0.9	-0.1	0.1	0.2	0.2	0.1	0.2	-0.0
Lung FVC	1.3	6.8	16.6	1.8	-2.6	-2.0	3.7	4.1	3.1	-2.8	-2.9	-3.0	-2.0	-2.6	-2.9	-2.1	-2.5	-2.9	-2.4	-2.9	-2.8	-2.8	-2.3	-2.0	-2.1	-0.8	-2.4	-2.3	-2.8	-2.7	-2.6	-2.7	-1.9
Neuroticism	2.3	5.5	9.7	-1.0	2.9	1.4	-2.7	-1.4	-1.9	3.0	3.1	3.1	1.2	2.3	2.4	1.2	2.9	2.7	1.9	3.1	3.1	3.1	1.7	1.5	1.0	1.8	2.0	1.9	3.0	3.0	2.4	3.0	1.0
Chronotype (morning person)	0.3	0.6	1.8	0.9	0.3	-0.9	-0.9	0.9	-0.0	0.9	1.3	1.0	-0.6	0.3	0.2	-0.5	1.0	0.6	-0.1	0.9	1.1	1.2	-0.0	-0.5	-1.3	-0.5	-0.3	-0.2	1.2	1.0	0.4	1.1	-0.8
Hair Pigment	0.3	8.4	17.1	-2.8	2.2	3.1	-2.2	0.2	-2.6	3.4	3.2	4.1	3.0	3.2	3.2	1.9	3.2	3.0	3.0	2.9	3.2	3.3	2.7	2.2	1.8	2.4	3.0	2.9	3.2	3.3	3.2	3.3	2.6
Tanning	0.1	1.6	3.0	-1.1	1.4	1.2	-0.4	0.3	-0.4	1.3	1.4	0.1	1.7	1.3	1.3	1.3	1.4	1.4	1.5	1.3	1.5	1.3	0.7	1.6	1.5	0.6	1.6	1.4	1.3	1.3	1.5	1.3	1.6
Hand grip strength (left)	0.3	0.7	2.3	-0.8	-0.3	0.5	-0.3	-1.5	-0.8	-0.7	-1.0	-0.7	0.9	-0.2	-0.4	1.0	-1.1	-0.5	0.4	-0.9	-1.0	-0.9	0.8	1.3	0.9	0.0	0.1	0.0	-1.0	-0.9	-0.4	-1.0	1.2
Number of treatments/medications taken	0.9	1.7	5.1	1.3	-0.7	-1.1	0.9	1.0	1.4	-0.8	-0.7	-1.3	-1.8	-1.0	-0.9	-2.2	-0.8	-0.9	-1.6	-0.5	-0.5	-0.8	-1.6	-2.2	-1.9	-2.0	-1.1	-1.8	-0.6	-0.6	-0.9	-0.6	-1.9
Average weekly spirits intake	0.1	0.1	0.7	-0.4	-0.3	0.2	-0.3	-0.3	-0.4	-0.1	-0.2	-0.8	0.6	0.2	0.1	0.1	-0.2	-0.0	0.3	-0.1	-0.2	-0.3	0.5	-0.3	-0.0	-0.6	0.2	0.2	-0.1	-0.1	0.1	-0.1	0.6
Sensitivity / hurt feelings	1.6	2.7	6.9	-1.4	2.6	1.4	-2.1	-1.3	-1.4	1.9	1.7	1.5	1.2	1.7	1.7	0.9	1.7	1.8	1.7	2.0	1.8	1.7	1.4	1.4	1.3	1.4	1.6	1.7	1.7	1.7	1.7	1.7	1.3
Frequency of depressed mood in last 2 weeks	4.3	6.0	8.2	-2.6	2.7	2.4	-2.7	-1.4	-2.5	2.9	2.7	2.6	2.0	2.7	2.8	1.6	2.6	2.6	2.6	2.5	2.8	2.7	2.3	2.2	2.1	1.9	2.6	2.9	2.5	2.5	2.6	2.4	1.6
Hearing difficulty/problems: Yes	2.2	3.4	6.2	-2.5	1.8	2.4	-1.6	-1.1	-1.6	1.8	1.6	0.8	2.4	2.0	2.0	1.3	1.6	1.9	2.2	1.6	1.8	1.6	1.8	1.8	1.7	1.4	2.1	2.1	1.6	1.6	2.0	1.4	2.3
Relative age of first facial hair	0.4	0.9	2.5	-0.0	1.0	0.3	-1.2	1.0	-0.9	1.2	1.4	1.6	0.2	0.7	0.7	0.4	1.2	1.1	0.1	1.2	1.5	1.4	0.6	0.1	-0.1	0.5	0.5	-0.1	1.4	1.2	0.8	1.4	-0.2
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.9	-0.7	1.4	0.7	-1.7	-0.7	-0.8	1.2	1.0	1.1	0.4	1.1	1.0	0.8	1.2	1.1	1.0	1.3	1.2	0.9	0.9	0.8	0.8	-0.5	0.9	1.0	1.2	1.2	1.1	1.2	0.2
Ever used hormone-replacement therapy (HRT)	0.4	0.6	1.3	-0.5	1.0	0.8	-0.7	-0.4	-0.5	1.0	1.0	0.3	0.9	0.8	0.9	0.0	1.0	0.9	0.6	0.9	1.2	0.8	0.3	0.3	0.2	0.2	0.9	0.6	0.9	0.8	0.9	0.9	0.7
Ever had hysterectomy (womb removed)	0.5	0.6	2.7	-0.5	0.7	0.8	-0.7	-0.2	-0.1	0.9	0.8	1.7	0.6	0.8	0.8	-0.3	0.7	0.6	0.6	0.7	0.8	0.9	0.2	0.6	0.3	1.1	0.9	1.2	0.7	0.7	0.7	0.7	0.5
Systolic blood pressure, automated reading	0.3	1.0	2.4	1.5	-1.6	-1.3	0.9	0.5	1.3	-0.8	-0.4	0.1	-1.4	-1.0	-1.0	-0.7	-0.6	-0.7	-1.2	-0.8	-0.5	-0.4	-1.3	-0.8	-1.1	-0.7	-1.3	-1.2	-0.5	-0.6	-0.9	-0.5	-1.5
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	4.5	1.2	-1.7	-1.6	0.9	-1.0	0.5	-1.5	-1.3	-0.9	-1.7	-1.6	-1.3	-0.8	-1.7	-1.5	-1.6	-1.4	-1.5	-1.2	-1.3	-1.0	-1.0	-1.4	-1.6	-2.1	-1.4	-1.5	-1.7	-1.4	-1.5
Angina	0.2	0.3	1.4	0.5	1.0	-0.2	-0.1	0.7	0.4	0.3	0.4	-0.3	-0.4	0.1	0.0	-1.2	0.7	0.2	-0.3	0.7	0.5	0.3	-0.4	-0.9	-1.1	0.1	-0.1	-0.1	0.5	0.5	0.2	0.5	-0.3
Medication for hormone replacement therapy	0.6	0.7	1.9	0.9	-0.9	-0.8	1.1	1.3	0.7	-0.7	-0.4	-0.3	-0.7	-0.9	-0.8	-1.3	-0.4	-0.8	-1.3	-0.7	-0.6	-0.5	-1.1	-1.2	-1.4	0.2	-0.7	-0.6	-0.4	-0.5	-0.7	-0.4	-0.8
Vitamin and mineral supplements	4.3	5.8	12.6	-2.7	2.4	2.6	-2.1	-3.5	-2.6	2.1	1.7	0.9	3.2	2.5	2.4	2.5	1.4	2.1	2.7	1.9	1.8	1.6	2.8	3.0	2.6	2.6	2.8	2.9	1.7	1.8	2.3	1.7	3.3
Supplements: Zinc	0.8	0.8	2.4	1.5	0.2	-1.2	-1.0	1.3	0.8	-0.2	-0.0	-0.1	-1.2	-0.7	-0.7	-1.2	-0.0	-0.1	-1.1	0.3	0.1	0.0	-1.1	-1.2	-1.5	-1.5	-0.9	-1.5	0.3	0.2	-0.4	0.3	-1.4
Medication: Co-codamol	0.1	0.1	0.5	-0.6	0.2	0.7	-0.3	-0.3	-0.4	0.1	-0.2	0.4	0.2	0.3	0.3	-0.4	0.0	-0.0	0.2	-0.0	-0.0	-0.1	0.3	0.1	0.1	-0.5	0.5	0.7	0.0	0.0	0.4	0.0	0.1
Medication: Metformin	1.0	1.4	3.4	0.4	-1.4	-0.7	1.7	-0.6	0.5	-1.3	-1.5	-1.3	-1.3	-0.9	-0.9	-0.7	-1.8	-1.4	-0.5	-1.5	-1.6	-1.4	-0.5	-0.7	-0.4	-0.7	-0.9	-0.8	-1.5	-1.4	-1.2	-1.6	-1.2
Diabetes (father)	1.1	1.4	4.4	-2.1	0.4	2.0	0.3	-1.4	-1.4	0.8	0.5	0.5	1.5	1.3	1.2	0.8	0.3	0.9	1.3	0.6	0.6	0.5	1.5	0.8	1.2	1.8	1.7	1.6	0.7	0.7	1.1	0.6	1.4
Diabetes (mother)	0.1	0.1	0.6	-0.3	0.6	0.1	-0.8	0.1	-0.8	0.1	0.2	-0.5	0.3	0.1	0.2	-0.2	0.3	0.3	-0.1	0.3	0.3	0.1	-0.0	-0.4	-0.1	-0.1	0.2	0.1	0.3	0.2	0.2	0.2	0.3
Severe depression (siblings)	0.6	0.7	2.4	-0.4	0.8	0.5	-0.7	0.1	-0.8	0.9	0.8	1.3	0.9	0.7	0.9	-0.5	1.0	0.7	0.2	1.0	0.9	0.9	0.3	0.4	-0.2	1.5	0.7	0.4	1.0	1.0	0.8	1.0	1.2
Pack years adult smoking proportion	1.5	2.3	5.2	-1.5	1.7	1.5	-1.3	-1.8	-2.3	1.4	1.3	1.5	1.5	1.4	1.7	1.6	1.1	1.4	1.5	1.4	1.4	1.4	1.7	1.8	1.4	1.8	1.5	1.6	1.2	1.2	1.3	1.2	1.6
Impedance of leg (right)	0.4	2.0	7.0	2.6	-0.1	-2.2	0.2	2.5	1.3	-0.7	-0.2	-0.4	-1.8	-1.4	-1.4	-1.4	0.1	-0.6	-2.1	-0.1	-0.1	-0.2	-1.6	-2.0	-2.3	-0.2	-1.8	-2.0	-0.1	-0.3	-1.1	-0.2	-1.9
Leg fat-free mass (left)	0.3	1.5	8.0	-2.2	-0.4	1.7	-0.9	-2.8	-1.3	0.6	0.2	1.0	1.7	1.2	1.0	0.9	0.2	0.3	1.7	-0.2	-0.0	0.3	1.4	1.7	1.6	-0.3	1.4	1.9	0.0	0.1	0.8	-0.0	1.9
Trunk fat percentage	0.2	0.8	6.3	-1.4	0.3	1.3	-1.0	-2.5	-1.4	0.5	0.2	0.4	0.9	0.8	0.7	0.1	0.3	0.4	0.7	0.2	0.2	0.2	1.0	0.4	0.5	-1.0	1.0	1.4	0.3	0.3	0.7	0.3	1.1
Hand grip strength (right)	0.2	0.5	2.5	-0.8	-0.0	0.5	-0.3	-1.6	-0.5	-0.6	-0.9	-1.4	0.8	-0.1	-0.4	0.6	-0.8	-0.5	0.6	-0.7	-0.8	-0.9	0.8	0.6	0.5	-0.4	0.1	0.1	-0.9	-0.8	-0.2	-0.9	1.1
Townsend deprivation index at recruitment	2.4	3.4	6.9	-2.0	1.9	1.9	-1.9	-2.6	-2.4	1.9	1.8	0.9	1.8	2.1	2.2	1.1	1.7	2.0	1.9	2.0	1.8	1.6	1.9	1.1	1.3	0.3	2.2	1.7	2.0	1.9	2.1	1.9	1.7
Current tobacco smoking	0.8	1.3	4.6	-1.4	1.1	1.3	-1.4	-2.1	-2.0	0.7	0.5	0.3	1.4	0.9	1.1	1.5	0.6	1.0	1.0	0.8	0.7	0.5	1.3	1.0	1.4	1.0	1.3	0.8	0.7	0.7	0.9	0.6	1.4
Average weekly fortified wine intake	1.6	1.9	4.6	2.1	-1.2	-2.0	0.8	1.7	1.4	-1.2	-1.0	-0.6	-1.7	-1.5	-1.4	-1.3	-0.7	-1.2	-1.8	-0.9	-1.0	-1.0	-1.7	-1.7	-1.5	-1.5	-1.7	-1.1	-0.9	-1.0	-1.3	-0.9	-1.5
Maternal smoking around birth	9.1	13.2	18.3	-3.1	4.3	3.4	-3.1	-2.6	-3.9	3.8	4.0	2.3	3.5	3.8	4.1	3.0	4.0	4.1	3.5	4.2	4.0	3.9	3.4	3.1	2.6	3.5	3.9	3.3	4.1	4.1	4.0	4.1	3.2
Fed-up feelings	3.3	6.1	9.4	-2.0	3.0	2.2	-2.9	-1.5	-2.8	2.9	2.9	2.1	1.4	2.6	2.7	1.7	3.0	2.9	2.2	2.8	3.1	2.8	2.3	1.8	1.4	2.2	2.4	2.6	2.9	2.8	2.5	2.9	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	2.2	-1.4	1.3	1.1	-1.3	-0.9	-1.0	1.4	1.1	0.8	1.1	1.4	1.4	0.8	1.0	1.2	1.5	1.1	1.3	1.1	1.1	1.3	1.3	1.5	1.2	1.5	1.0	1.0	1.1	0.9	1.1
Relative age voice broke	0.8	1.2	2.9	-0.3	1.3	0.6	-1.0	0.3	-1.2	1.3	1.6	0.9	0.8	0.9	1.1	0.4	1.6	1.5	0.5	1.6	1.7	1.6	0.6	-0.1	-0.0	0.4	0.9	0.7	1.7	1.5	1.2	1.6	0.6
Taking other prescription medications	0.2	0.3	1.7	0.6	-0.2	-0.6	0.2	0.0	0.1	-0.4	-0.3	-0.5	-1.1	-0.4	-0.4	0.1	-0.3	-0.2	-0.6	-0.2	-0.3	-0.4	-0.1	-0.8	-0.3	-0.7	-0.6	-0.8	-0.3	-0.3	-0.4	-0.3	-1.3
Age when periods started (menarche)	1.8	4.3	7.9	2.8	-1.3	-2.8	1.3	2.1	2.7	-2.0	-1.9	-2.0	-2.2	-2.2	-2.4	-1.9	-1.5	-1.9	-2.3	-1.5	-1.7	-2.0	-2.5	-2.4	-1.9	-2.3	-2.5	-1.8	-1.7	-1.7	-2.0	-1.7	-2.1
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	2.3	0.9	-1.4	-1.0	1.1	0.5	1.5	-1.1	-1.1	-0.3	-1.0	-1.2	-1.1	-0.7	-1.2	-1.2	-1.1	-1.2	-1.1	-1.0	-1.4	-0.6	-0.4	-0.5	-1.1	-1.1	-1.2	-1.2	-1.3	-1.2	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.7	0.8	-0.5	-0.7	0.0	1.3	1.1	-0.3	-0.2	-0.1	-0.7	-0.6	-0.6	-1.0	-0.2	-0.4	-0.6	-0.4	-0.1	-0.2	-1.1	-1.1	-1.0	-0.8	-0.5	-0.4	-0.2	-0.2	-0.5	-0.1	-1.0
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.6	-0.2	-0.1	0.1	-0.2	-0.1	0.4	-0.1	-0.4	0.1	0.2	-0.0	-0.4	-0.8	-0.2	-0.3	0.1	-0.3	-0.3	-0.4	-0.0	-0.4	-0.5	0.3	0.1	0.4	-0.3	-0.3	-0.0	-0.3	0.2
Qualifications: CSEs or equivalent	0.8	1.0	3.7	-1.1	1.0	1.1	-0.8	-1.9	-1.5	0.5	0.3	-0.7	0.8	1.0	0.9	1.7	0.3	0.9	1.2	0.9	0.3	0.4	1.7	1.0	1.1	0.4	0.9	1.2	0.6	0.7	0.9	0.6	1.0
Serious illness, injury or assault to yourself	2.0	2.4	4.8	-1.6	1.9	1.7	-1.2	-0.9	-1.5	1.6	1.4	1.9	1.2	1.8	1.7	1.4	1.3	1.7	1.6	1.6	1.4	1.4	1.6	1.7	1.7	1.4	1.7	2.2	1.5	1.6	1.7	1.5	1.0
High blood pressure	0.5	1.5	7.0	1.6	0.5	-1.1	-0.5	1.7	0.4	0.1	0.7	-0.9	-1.4	-0.4	-0.1	-2.3	0.8	0.2	-1.2	0.8	0.8	0.4	-1.4	-2.4	-2.6	-2.1	-0.5	-1.0	0.9	0.8	-0.0	0.9	-1.8
Hayfever, allergic rhinitis or eczema	0.1	0.2	1.2	-0.9	0.1	0.7	-0.2	-1.1	-0.7	0.1	-0.1	0.8	0.2	0.2	0.2	0.6	-0.3	0.1	0.2	-0.1	-0.2	-0.1	0.5	1.0	1.1	-0.1	0.3	0.2	-0.1	-0.1	0.1	-0.1	0.3
Multivitamins +/- minerals	2.4	3.1	7.2	2.1	-1.6	-2.0	1.1	2.5	1.7	-1.4	-1.1	-0.4	-2.5	-1.8	-1.6	-1.9	-0.8	-1.3	-2.2	-1.2	-1.1	-0.9	-2.2	-2.5	-2.0	-2.0	-2.0	-2.3	-1.0	-1.1	-1.6	-1.0	-2.7
Stomach or abdominal pain in last month	0.3	0.4	3.6	-0.8	0.5	0.6	-0.9	-1.0	-1.9	0.2	0.2	0.4	0.6	0.3	0.6	0.9	-0.0	0.4	0.3	0.2	0.2	0.4	0.9	0.8	0.7	0.5	0.5	0.5	0.1	0.1	0.3	0.1	0.8
Supplements: Glucosamine	1.3	1.7	3.9	1.3	-1.4	-1.2	1.4	1.4	1.5	-1.3	-1.3	-0.9	-1.2	-1.4	-1.5	-0.9	-1.3	-1.2	-1.4	-1.3	-1.2	-1.3	-1.4	-1.5	-1.0	-1.3	-1.4	-2.0	-1.2	-1.3	-1.4	-1.2	-1.3
Diverticular disease/diverticulitis (self-reported)	8.0	9.4	13.2	-3.3	3.2	3.5	-2.7	-1.6	-2.6	3.4	3.0	2.8	3.6	3.5	3.3	2.1	2.9	3.1	3.1	3.0	3.2	3.1	3.0	3.2	2.4	2.7	3.5	3.2	3.0	3.1	3.4	3.0	3.6
Medication: Atenolol	0.9	1.2	2.3	1.2	-0.6	-1.0	0.8	1.1	0.8	-1.0	-1.1	-1.5	-1.4	-0.9	-1.2	-1.4	-1.0	-1.1	-1.2	-0.8	-1.0	-1.2	-0.7	-1.4	-1.5	-0.7	-1.0	-1.3	-0.9	-0.9	-1.0	-0.8	-1.4
Medication: Levothyroxine sodium	0.1	0.2	0.6	0.2	0.7	-0.1	-0.5	0.8	0.6	0.3	0.4	0.2	-0.1	0.2	0.2	-0.2	0.5	0.4	-0.1	0.5	0.5	0.4	-0.4	0.2	-0.1	-0.4	0.2	0.2	0.5	0.5	0.3	0.5	-0.3
Sitting height	0.3	1.9	4.5	0.9	-2.1	-1.2	0.9	-1.6	-0.1	-1.6	-1.9	-0.6	-0.9	-1.2	-1.4	0.2	-1.8	-1.8	-0.5	-2.0	-2.1	-1.7	-0.1	-0.1	0.1	-0.8	-1.3	-0.7	-2.0	-2.0	-1.6	-2.0	-0.5
Chronic bronchitis/emphysema (father)	0.7	0.8	1.8	-0.8	1.4	1.1	-0.8	-0.8	-0.3	0.9	0.7	1.3	1.0	0.9	1.0	0.3	0.5	1.0	1.0	1.0	0.9	0.7	0.2	1.0	1.1	0.8	1.2	1.3	0.9	0.9	0.9	0.8	0.9
High blood pressure (mother)	0.2	0.2	0.9	-0.1	0.1	0.1	0.5	1.0	0.3	-0.3	-0.5	-0.6	-0.2	0.0	-0.4	0.6	-0.4	-0.2	0.3	-0.6	-0.5	-0.6	0.4	0.5	0.6	0.9	-0.1	0.0	-0.5	-0.5	-0.2	-0.6	-0.5
Body mass index (BMI)	0.8	3.2	14.2	-3.0	1.1	2.6	-1.5	-3.8	-2.1	1.2	0.7	0.7	2.3	1.8	1.8	1.3	0.6	1.2	2.2	0.8	0.7	0.7	2.0	1.9	2.1	0.4	2.3	2.5	0.8	0.9	1.6	0.8	2.5
Impedance of leg (left)	0.4	2.0	7.0	2.6	0.1	-2.1	0.2	2.4	1.4	-0.7	-0.3	-0.8	-1.8	-1.3	-1.4	-1.7	-0.0	-0.6	-2.0	0.1	-0.1	-0.4	-1.6	-2.3	-2.3	-0.8	-1.8	-1.9	-0.1	-0.2	-1.0	-0.1	-1.9
Leg predicted mass (left)	0.3	1.5	8.2	-2.2	-0.3	1.7	-0.8	-2.9	-1.3	0.6	0.1	0.8	1.7	1.1	1.0	0.9	0.1	0.3	1.7	-0.3	-0.1	0.2	1.4	1.7	1.6	-0.2	1.4	1.9	-0.0	0.0	0.7	-0.1	1.9
Trunk fat mass	0.3	1.5	9.1	-1.9	0.4	1.7	-1.3	-3.0	-1.7	0.8	0.4	0.6	1.5	1.2	1.1	0.5	0.5	0.6	1.3	0.4	0.3	0.4	1.4	1.0	1.1	-0.7	1.4	1.9	0.4	0.5	1.0	0.4	1.7
Waist circumference	1.1	4.1	11.9	-3.0	1.6	2.7	-2.1	-3.4	-2.3	1.8	1.4	1.6	2.4	2.2	2.2	1.2	1.4	1.8	2.4	1.4	1.4	1.4	2.0	1.8	2.1	0.4	2.5	2.7	1.5	1.5	2.0	1.5	2.3
Number of incorrect matches in round	0.3	0.5	2.1	-1.4	-0.4	1.0	1.1	0.2	-0.1	0.1	-0.3	0.6	0.6	0.4	0.3	1.0	-0.4	-0.1	0.8	-0.5	-0.4	-0.3	0.9	1.2	1.5	1.4	0.5	0.7	-0.5	-0.3	0.1	-0.4	0.6
Past tobacco smoking	0.5	0.9	2.2	1.1	-1.2	-1.1	1.2	0.7	0.7	-1.2	-1.1	-0.1	-0.9	-1.2	-1.1	0.2	-1.5	-1.0	-1.1	-1.0	-1.3	-1.0	-0.8	0.2	0.0	0.2	-1.2	-0.9	-1.0	-1.1	-1.2	-1.0	-0.7
Alcohol usually taken with meals	1.3	2.1	4.2	1.1	-1.2	-1.2	0.4	0.4	0.4	-1.8	-2.0	-1.3	-1.5	-1.6	-1.6	-0.2	-1.9	-1.7	-1.2	-1.9	-1.9	-1.8	-0.9	-0.5	-0.2	-1.5	-1.4	-1.2	-2.0	-2.0	-1.7	-2.0	-1.5
Nervous feelings	1.6	2.9	6.6	-0.3	1.9	0.8	-2.3	-1.1	-1.3	2.1	2.2	2.6	0.6	1.7	1.7	1.3	2.0	2.1	1.3	2.3	2.2	2.2	1.1	0.9	1.1	0.6	1.3	1.5	2.3	2.2	1.7	2.2	0.3
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.8	2.9	-1.5	1.4	1.4	-1.3	-1.5	-1.6	1.3	1.2	1.2	1.1	1.4	1.4	1.6	1.1	1.4	1.6	1.2	1.3	1.3	1.7	1.4	1.5	1.0	1.4	1.4	1.1	1.2	1.3	1.1	0.8
Hearing difficulty/problems with background noise	0.9	1.4	3.3	-1.8	1.1	1.8	-0.4	-1.3	-1.0	0.8	0.6	-0.1	1.8	1.2	1.3	1.3	0.6	1.1	1.6	0.8	0.8	0.5	1.3	1.6	1.6	1.4	1.6	1.1	0.7	0.8	1.2	0.7	1.6
Hair/balding pattern: Pattern 2	0.2	0.2	0.9	0.3	0.0	-0.3	-0.4	-0.7	-0.2	-0.6	-0.7	-0.9	-0.3	-0.3	-0.4	0.4	-0.5	-0.4	-0.1	-0.6	-0.6	-0.7	0.2	0.4	0.2	-0.4	-0.3	-0.4	-0.7	-0.6	-0.4	-0.7	-0.3
Had menopause	0.9	1.2	3.4	-1.2	0.9	1.3	-0.8	-0.7	-0.9	1.2	1.2	1.8	0.9	1.1	1.2	1.0	1.0	1.0	0.9	0.9	1.1	1.2	0.9	1.6	1.2	1.3	1.1	0.9	0.9	0.9	1.0	0.9	0.8
Had other major operations	0.3	0.4	2.7	0.7	-0.0	-0.6	-0.1	1.6	0.9	-0.1	-0.1	0.1	-0.6	-0.4	-0.4	-1.4	0.1	-0.5	-0.5	-0.2	-0.0	-0.1	-0.9	-0.8	-0.9	-1.3	-0.4	-0.0	-0.3	-0.3	-0.2	-0.3	-0.6
Forced vital capacity (FVC)	0.6	2.4	5.9	1.5	-1.5	-1.7	1.8	2.4	2.2	-1.6	-1.5	-1.6	-1.1	-1.6	-1.8	-1.5	-1.1	-1.7	-1.3	-1.6	-1.5	-1.5	-1.6	-1.2	-1.6	-1.1	-1.7	-1.4	-1.5	-1.4	-1.5	-1.4	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	3.2	1.1	-1.4	-1.2	1.2	1.0	1.8	-1.2	-1.2	-0.6	-1.1	-1.3	-1.3	-1.5	-0.9	-1.2	-1.3	-1.2	-1.1	-1.1	-1.6	-1.6	-1.4	-0.7	-1.2	-0.7	-1.0	-1.0	-1.2	-1.0	-1.1
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	2.6	-1.1	1.5	1.3	-1.5	-1.6	-1.1	1.1	1.0	-0.1	1.0	1.3	1.5	1.0	1.1	1.2	1.4	1.4	1.1	1.0	0.8	0.6	1.5	-0.1	1.6	1.5	1.1	1.2	1.3	1.2	0.8
Qualifications: None of the above	3.2	6.8	11.9	-3.2	2.7	3.0	-1.7	-2.9	-3.3	2.3	2.0	1.6	2.3	2.7	2.7	3.3	1.8	2.5	3.1	2.2	2.0	2.0	3.1	3.3	3.4	3.3	3.0	2.7	1.9	2.1	2.5	1.9	2.1
Financial difficulties in last 2 years	1.4	1.8	6.3	-2.1	1.6	1.8	-1.4	-2.4	-2.5	0.7	0.3	-0.3	1.4	1.3	1.2	1.5	0.5	0.9	1.4	0.7	0.4	0.2	2.3	1.3	1.6	0.7	1.6	1.5	0.5	0.6	1.2	0.5	1.5
Mouth/teeth dental problems	2.7	4.2	6.2	2.4	-2.5	-2.5	1.7	1.5	1.6	-2.1	-2.0	-1.4	-2.4	-2.3	-2.3	-1.2	-1.6	-2.3	-2.1	-2.3	-2.0	-1.9	-1.9	-1.8	-1.4	-1.5	-2.2	-2.0	-2.2	-2.2	-2.3	-2.1	-2.5
Heart attack	0.1	0.1	0.4	0.0	-0.0	-0.3	-0.0	-0.4	0.2	-0.3	-0.2	-0.5	0.1	-0.3	-0.3	0.7	-0.3	-0.0	-0.2	-0.3	-0.2	-0.4	-0.2	0.6	0.4	-0.1	-0.3	-0.5	-0.3	-0.3	-0.3	-0.3	0.0
Allergy	0.2	0.5	1.7	1.1	-0.3	-0.9	0.7	1.2	0.6	-0.7	-0.4	-1.3	-0.8	-0.7	-0.6	-0.3	-0.2	-0.5	-0.5	-0.5	-0.4	-0.5	-0.5	-0.9	-0.8	0.0	-0.8	-0.6	-0.5	-0.5	-0.7	-0.5	-0.9
Pain all over the body in last month	1.3	1.4	2.9	-1.5	1.1	1.4	-0.6	-0.0	-0.3	1.5	1.3	1.7	1.4	1.4	1.4	-0.1	1.1	1.2	1.0	1.2	1.4	1.3	0.7	1.0	0.4	1.5	1.4	1.2	1.3	1.2	1.3	1.2	1.4
Diabetes (self-reported)	0.1	0.2	1.5	-0.5	-0.2	0.3	0.8	-0.9	0.3	-0.3	-0.4	-1.2	-0.2	0.1	0.1	-1.1	-0.6	-0.3	0.2	-0.2	-0.4	-0.5	-0.1	-0.4	-0.5	-0.4	0.1	-0.1	-0.3	-0.2	-0.0	-0.3	-0.0
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.6	0.4	-0.3	-0.6	0.3	-0.6	0.9	-0.8	-0.9	-1.3	-0.8	-0.6	-0.8	-0.4	-0.7	-0.7	-0.5	-0.6	-0.8	-1.0	-0.5	-0.8	-0.1	-0.9	-0.8	-1.0	-0.9	-0.9	-0.6	-0.9	-0.6
Medication: Ramipril	0.5	0.6	3.6	1.3	0.4	-0.9	-0.9	1.9	0.4	0.0	0.3	-0.4	-0.5	-0.4	-0.2	-1.1	0.7	0.0	-0.7	0.2	0.4	0.3	-1.2	-1.1	-1.2	-1.4	-0.5	-0.3	0.3	0.3	-0.2	0.4	-0.6
Medication: Simvastatin	0.2	0.3	2.6	0.4	0.1	-0.2	-0.8	0.1	-0.2	0.3	0.3	0.2	-0.7	-0.1	0.2	-1.6	0.2	-0.1	-0.5	0.2	0.5	0.4	-0.5	-1.1	-1.4	-0.3	-0.1	-0.5	0.3	0.2	-0.1	0.3	-1.0
Fluid intelligence score	0.9	1.8	4.1	1.1	-1.0	-1.2	1.1	0.1	1.8	-1.5	-1.9	-2.0	-1.1	-1.2	-1.6	-1.2	-1.6	-1.6	-0.9	-1.4	-1.7	-1.9	-0.8	-1.2	-0.9	-0.3	-1.4	-0.8	-1.7	-1.6	-1.3	-1.7	-0.7
Illnesses of siblings	2.9	4.0	6.1	2.4	-2.5	-2.3	1.3	2.0	2.2	-2.0	-1.7	-1.0	-2.1	-2.1	-2.1	-2.0	-1.8	-2.0	-2.4	-2.0	-1.8	-1.6	-2.3	-2.2	-2.2	-1.7	-2.2	-2.0	-1.7	-1.8	-2.0	-1.7	-2.4
Neuroticism score	3.5	7.4	12.2	-1.6	3.3	1.9	-3.1	-1.5	-2.4	3.3	3.5	3.3	1.5	2.7	2.9	1.7	3.3	3.1	2.2	3.4	3.5	3.5	2.0	2.1	1.6	2.3	2.4	2.4	3.3	3.3	2.7	3.4	1.1
Weight	0.4	2.1	11.8	-2.4	0.3	2.0	-1.2	-3.4	-1.8	0.8	0.4	0.8	2.0	1.4	1.3	1.0	0.5	0.7	1.9	0.3	0.3	0.4	1.6	1.6	1.8	-0.2	1.7	2.1	0.3	0.4	1.1	0.3	2.2
Impedance of arm (right)	1.2	5.4	15.1	3.9	-2.0	-3.5	1.1	3.2	2.0	-1.8	-1.1	-0.4	-3.2	-2.5	-2.5	-2.1	-1.1	-1.8	-3.2	-1.4	-1.3	-1.1	-2.6	-2.6	-3.1	-2.2	-3.1	-2.6	-1.1	-1.4	-2.3	-1.2	-3.2
Arm fat percentage (right)	0.2	0.8	7.4	-1.5	-0.1	1.2	-0.9	-2.7	-1.3	0.3	-0.0	0.5	0.9	0.6	0.6	0.4	-0.1	0.3	0.8	-0.1	-0.1	-0.0	0.9	0.7	0.9	-0.8	0.9	1.4	0.0	0.1	0.4	0.0	1.0
Trunk fat-free mass	0.3	1.5	8.0	-2.1	-0.3	1.6	-0.8	-2.8	-0.9	0.5	0.0	0.6	2.0	1.1	0.9	1.1	0.1	0.3	1.8	-0.4	-0.1	0.1	1.3	1.8	1.9	0.1	1.4	1.5	-0.2	-0.1	0.7	-0.2	2.1
Hip circumference	0.4	1.7	10.6	-2.2	0.6	1.9	-1.3	-3.3	-2.0	0.5	0.1	0.6	1.3	1.1	1.0	1.3	0.2	0.6	1.5	0.2	-0.0	0.1	1.4	1.7	2.0	-0.3	1.5	2.0	0.1	0.2	0.8	0.1	1.4
Time employed in main current job	0.8	0.9	1.7	-0.4	1.2	0.6	-0.5	1.0	-0.8	1.1	1.2	1.0	0.4	0.9	1.0	0.8	1.3	1.0	0.8	1.1	1.2	1.3	0.8	1.2	0.6	0.2	0.7	1.3	1.1	1.1	0.9	1.1	0.2
Alcohol intake versus 10 years previously	2.3	3.4	4.9	-1.8	1.9	1.8	-2.2	-1.5	-2.0	1.9	1.8	1.9	2.0	1.9	1.9	1.3	1.8	1.9	1.9	1.8	1.8	1.8	1.9	1.9	1.4	1.0	1.9	2.1	1.8	1.9	1.9	1.8	2.1
Father’s age at death	1.1	1.4	4.5	1.7	-1.4	-1.7	0.9	2.1	1.7	-1.0	-0.7	-1.4	-0.9	-1.1	-1.4	-0.3	-0.3	-1.0	-0.9	-1.1	-0.7	-0.8	-1.0	-1.4	-1.2	-0.8	-1.5	-1.6	-0.9	-1.1	-1.1	-1.0	-0.9
Worrier / anxious feelings	1.3	2.5	4.0	-0.9	1.9	1.2	-1.9	-1.4	-1.6	1.8	1.9	1.9	0.9	1.6	1.6	1.5	1.7	1.8	1.4	2.0	1.9	1.9	1.5	1.4	1.0	0.9	1.4	1.5	1.9	1.9	1.6	1.9	0.7
Frequency of tiredness / lethargy in last 2 weeks	2.6	4.2	7.2	-2.7	2.6	2.4	-1.6	-1.1	-2.3	2.1	1.8	1.2	2.1	2.2	2.3	1.9	1.9	2.2	2.3	1.9	1.9	1.7	2.2	2.3	2.3	1.8	2.3	2.3	1.8	1.8	2.1	1.7	2.1
Falls in the last year	2.5	3.4	5.0	-2.0	2.1	2.0	-1.5	-1.0	-1.9	2.0	1.8	1.7	1.8	2.0	2.0	1.4	1.8	2.0	1.9	2.0	2.0	1.8	1.9	1.7	1.3	2.2	1.9	2.0	1.9	1.9	2.1	1.8	1.7
Hair/balding pattern: Pattern 3	2.6	3.9	7.2	-2.2	1.8	1.9	-1.6	-2.4	-2.2	1.9	1.8	2.0	2.0	1.9	2.0	2.5	1.3	2.1	1.9	1.9	1.8	1.8	2.0	2.7	2.3	1.4	2.0	2.1	1.8	1.9	1.9	1.9	1.9
Number of live births	0.3	0.4	1.6	0.2	-1.1	-0.3	1.3	0.8	0.5	-0.5	-0.6	0.2	-0.6	-0.5	-0.4	-0.7	-0.6	-0.7	-0.5	-0.7	-0.6	-0.4	-0.8	-0.9	-0.4	0.0	-0.4	-0.5	-0.6	-0.7	-0.6	-0.7	-0.6
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	7.1	1.8	-2.0	-2.0	1.9	2.7	2.5	-1.9	-1.9	-1.6	-1.4	-1.8	-2.1	-2.0	-1.5	-2.1	-1.6	-2.0	-1.9	-1.9	-1.9	-1.6	-1.8	-1.9	-2.0	-1.5	-1.9	-1.8	-1.8	-1.8	-1.2
Pulse rate	0.2	0.3	3.4	-0.1	-0.2	0.0	0.7	0.3	0.8	-0.5	-0.6	-1.8	0.1	-0.2	-0.4	-0.2	-0.6	-0.4	-0.1	-0.4	-0.4	-0.8	-0.0	-0.5	-0.2	-1.2	-0.3	-0.6	-0.6	-0.5	-0.2	-0.6	0.2
Happiness	1.1	1.3	3.4	-0.8	1.3	0.9	-1.5	-0.2	-1.0	1.4	1.4	1.9	0.7	1.0	1.4	0.8	1.4	1.3	0.9	1.3	1.5	1.5	0.5	1.0	1.2	0.1	1.2	1.0	1.3	1.3	1.1	1.3	0.5
Noisy workplace	0.2	0.3	1.4	0.0	0.4	0.0	-0.1	0.2	-0.1	0.5	0.4	1.2	0.1	0.5	0.4	0.8	0.1	0.6	0.4	0.4	0.5	0.4	0.3	1.1	0.9	0.1	0.4	0.6	0.5	0.5	0.3	0.5	-0.2
Qualifications: A levels/AS levels or equivalent	2.1	4.7	6.8	2.2	-2.3	-2.2	2.0	2.2	2.2	-2.4	-2.4	-2.0	-1.7	-2.3	-2.4	-1.7	-2.3	-2.3	-2.2	-2.3	-2.3	-2.2	-2.2	-1.7	-1.7	-2.6	-2.2	-2.4	-2.2	-2.3	-2.2	-2.2	-1.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.7	-0.4	-0.7	0.3	-0.6	-0.9	-0.7	-0.1	-0.2	0.8	0.3	-0.1	-0.0	-0.4	-0.6	-0.4	-0.3	-0.4	-0.3	-0.1	0.1	0.4	-0.4	0.0	0.1	0.1	-0.2	-0.2	-0.1	-0.2	0.4
Mouth/teeth dental problems: Dentures	0.3	0.5	3.0	-0.2	0.3	0.4	-1.0	-0.1	-0.6	0.7	0.9	1.7	0.1	0.6	0.7	0.6	0.6	0.8	0.4	0.7	0.7	1.0	0.3	0.5	0.6	0.2	0.4	0.8	0.8	0.8	0.6	0.8	-0.2
Asthma	0.1	0.2	2.3	0.2	-0.3	-0.4	-0.3	-0.0	0.1	0.5	0.5	1.5	-0.2	0.0	0.1	-0.9	0.6	0.1	-0.5	0.3	0.5	0.5	-0.6	-0.5	-0.6	0.1	0.1	0.0	0.6	0.5	0.2	0.6	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.7	-0.7	0.0	0.7	0.7	-0.7	0.1	0.1	-0.1	-0.4	0.7	0.6	0.1	0.3	0.0	0.1	0.7	-0.0	-0.0	-0.2	0.9	0.4	0.5	0.8	0.6	0.3	0.0	0.1	0.4	0.0	0.7
Medication: Cholesterol lowering	0.9	1.4	5.9	1.0	-0.7	-1.0	0.0	0.0	0.8	-0.9	-0.9	-1.8	-1.3	-0.9	-0.9	-2.4	-0.8	-1.0	-1.2	-0.8	-0.7	-0.9	-1.2	-2.1	-2.3	-1.0	-0.9	-1.4	-0.7	-0.8	-0.9	-0.8	-1.4
Depression (self-reported)	2.0	2.3	7.0	-0.8	1.7	1.1	-2.7	-1.4	-1.5	1.8	1.9	1.8	1.2	1.4	1.6	0.6	1.9	1.7	1.1	1.9	2.0	1.9	0.9	0.6	0.6	-0.3	1.3	1.0	1.9	1.9	1.6	1.9	1.0
Medication: Lansoprazole	0.1	0.1	1.4	0.1	-0.5	-0.3	-0.4	-0.8	0.3	-0.0	-0.0	1.2	-0.3	-0.1	-0.0	-0.3	-0.4	-0.0	-0.5	0.0	-0.1	-0.0	-0.4	-0.1	-0.0	0.2	-0.1	-0.0	0.1	0.1	-0.2	0.1	-0.5
Prospective memory result	0.2	0.2	2.0	-0.1	0.5	0.3	-0.0	1.4	-0.1	0.3	0.3	-0.7	0.2	0.3	0.2	-0.7	0.4	0.1	0.0	0.3	0.4	0.2	0.2	-0.3	-0.7	-0.8	0.2	0.2	0.3	0.3	0.4	0.3	0.2
Lung cancer (father)	13.1	15.3	24.9	-5.0	3.7	4.9	-2.2	-3.2	-2.9	4.0	3.6	3.2	4.7	4.3	4.2	2.9	3.8	3.9	4.7	3.6	3.6	3.5	3.8	3.8	3.8	4.2	4.5	4.3	3.5	3.6	4.3	3.4	4.7
Illnesses of mother	0.1	0.2	1.0	0.1	-1.0	-0.2	0.7	-0.5	0.5	-0.4	-0.3	0.1	-0.3	-0.3	-0.2	-0.2	-0.4	-0.3	-0.3	-0.4	-0.4	-0.3	-0.3	-0.5	-0.2	-0.4	-0.3	-0.6	-0.3	-0.3	-0.3	-0.3	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.7	11.9	2.1	-2.8	-2.3	2.7	3.4	3.1	-2.4	-2.4	-1.7	-1.9	-2.4	-2.6	-2.5	-2.1	-2.7	-2.3	-2.6	-2.4	-2.3	-2.5	-2.1	-2.3	-1.4	-2.4	-1.9	-2.4	-2.3	-2.4	-2.3	-1.7
Pulse wave Arterial Stiffness index	0.6	0.8	4.0	0.8	-0.8	-0.8	-0.3	0.2	0.3	-0.8	-0.7	-1.0	-0.9	-0.8	-0.8	-0.9	-0.6	-0.8	-0.9	-0.8	-0.7	-0.8	-0.7	-1.1	-1.2	-2.0	-0.9	-0.9	-0.7	-0.8	-0.7	-0.8	-1.0
Impedance of arm (left)	1.1	4.9	12.7	3.6	-1.8	-3.2	1.4	3.0	2.0	-1.8	-1.2	-0.7	-3.1	-2.3	-2.4	-2.0	-1.1	-1.8	-3.0	-1.4	-1.4	-1.2	-2.3	-2.4	-2.9	-1.9	-2.9	-2.5	-1.2	-1.4	-2.1	-1.2	-3.0
Arm fat mass (right)	0.4	1.6	10.8	-2.2	0.3	1.8	-1.2	-3.3	-1.6	0.6	0.1	0.6	1.5	1.1	1.0	0.7	0.2	0.5	1.4	0.1	0.1	0.2	1.4	1.3	1.5	-0.4	1.5	1.9	0.1	0.2	0.9	0.1	1.7
Trunk predicted mass	0.3	1.6	8.3	-2.2	-0.3	1.7	-0.8	-2.9	-0.9	0.5	0.0	0.5	2.0	1.1	0.9	1.2	0.1	0.3	1.8	-0.4	-0.1	0.1	1.4	1.8	2.0	0.2	1.4	1.5	-0.2	-0.1	0.7	-0.3	2.2
Standing height	0.1	1.0	3.4	1.2	-1.8	-1.3	0.8	0.3	0.9	-0.9	-0.9	0.1	-0.8	-1.0	-1.2	-0.8	-0.6	-1.3	-0.7	-1.4	-1.2	-0.8	-0.8	-0.5	-0.8	-1.3	-1.2	-0.7	-1.1	-1.2	-1.1	-1.2	-0.5
Length of working week for main job	0.2	0.2	1.4	-0.1	-0.3	0.0	0.0	0.6	0.6	-0.3	-0.4	0.4	-0.0	-0.3	-0.4	-1.2	-0.6	-0.5	-0.5	-0.3	-0.4	-0.2	-0.4	-0.1	-0.9	0.3	-0.2	-0.3	-0.4	-0.3	-0.3	-0.3	0.1
Exposure to tobacco smoke at home	0.9	1.0	4.5	1.3	-0.5	-0.9	-0.4	0.7	0.2	-0.3	0.1	-0.3	-1.3	-0.9	-0.4	-1.9	0.4	-0.5	-1.4	-0.1	0.1	0.2	-1.5	-1.9	-2.1	-1.6	-0.7	-1.2	0.1	-0.0	-0.5	0.1	-1.5
Breastfed as a baby	2.6	3.2	6.4	2.2	-1.6	-2.0	1.0	1.1	1.7	-1.6	-1.5	-1.6	-1.9	-1.8	-1.8	-2.4	-1.4	-1.9	-2.0	-1.4	-1.4	-1.4	-2.1	-2.5	-2.4	-2.4	-1.9	-2.1	-1.4	-1.6	-1.7	-1.4	-1.7
Tense / ‘highly strung’	10.3	17.1	24.4	-3.0	4.9	3.4	-4.3	-1.4	-3.7	4.9	4.8	4.6	3.1	4.5	4.5	3.4	4.8	4.7	4.1	4.9	4.9	4.9	3.7	3.5	3.2	2.9	4.0	3.9	4.8	4.8	4.5	4.8	2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.5	-0.5	1.1	0.7	-1.6	-1.4	-1.0	1.0	0.9	1.0	0.3	0.7	0.8	0.6	1.1	0.9	0.7	1.1	0.9	0.9	0.6	0.4	0.6	0.0	0.6	0.7	0.8	0.9	0.8	0.9	0.3
Hair/balding pattern: Pattern 4	0.4	0.9	2.9	0.3	-0.9	-0.4	1.3	1.7	0.9	-0.9	-1.0	-1.3	-0.3	-0.8	-0.9	-1.0	-1.0	-1.1	-0.5	-1.0	-1.0	-1.1	-0.8	-1.0	-0.6	-0.9	-0.7	-0.5	-1.1	-1.0	-0.8	-1.0	-0.0
Birth weight of first child	1.6	3.0	6.2	-2.5	1.0	2.2	-0.8	-2.1	-1.1	1.7	1.4	1.3	2.3	2.0	1.9	1.3	1.3	1.5	2.4	1.3	1.4	1.4	1.8	2.2	1.9	1.4	2.0	1.8	1.2	1.3	1.8	1.2	2.4
Peak expiratory flow (PEF)	3.3	7.6	14.1	1.7	-3.0	-2.2	3.8	1.7	3.0	-3.2	-3.5	-3.3	-1.4	-2.6	-3.1	-1.9	-3.5	-3.3	-1.9	-3.3	-3.5	-3.5	-2.0	-1.6	-1.5	-1.8	-2.5	-2.3	-3.5	-3.3	-2.8	-3.4	-0.7
Pulse wave reflection index	0.2	0.2	2.3	0.2	0.4	-0.2	-1.5	-0.7	-1.0	0.3	0.4	0.1	-0.1	0.1	0.2	-0.1	0.5	0.2	-0.1	0.3	0.3	0.3	0.2	-0.2	-0.6	-0.7	-0.1	0.1	0.3	0.3	0.2	0.3	-0.2
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.5	-0.3	1.2	0.5	0.3	-0.5	-0.2	0.1	-0.1	-0.8	0.3	0.3	0.3	0.6	-0.1	0.3	0.3	0.6	0.2	-0.2	0.3	0.5	0.9	0.4	0.5	0.1	0.1	0.2	0.3	0.2	0.3
Loud music exposure frequency	9.0	9.8	14.5	-3.1	3.8	3.2	-3.3	-3.1	-2.8	3.2	2.6	2.5	3.4	3.5	3.3	2.8	2.6	3.2	3.6	3.2	2.8	2.5	3.2	3.6	3.5	2.3	3.5	3.4	2.9	3.0	3.4	2.8	3.5
Qualifications: O levels/GCSEs or equivalent	2.4	3.9	6.4	2.5	-2.0	-2.5	1.6	1.4	2.1	-2.0	-1.7	-1.4	-2.0	-2.3	-2.3	-1.4	-1.8	-1.9	-2.2	-1.7	-1.8	-1.7	-2.3	-2.1	-1.8	-2.0	-2.3	-2.5	-1.6	-1.7	-2.1	-1.6	-1.8
Mouth/teeth dental problems: Bleeding gums	3.1	4.0	9.4	-2.6	2.3	2.6	-1.7	-2.8	-1.8	1.8	1.4	0.6	2.7	2.3	2.1	1.0	1.1	1.8	2.0	1.9	1.5	1.4	2.2	2.1	1.3	2.1	2.3	1.9	1.7	1.8	2.1	1.6	3.1
Blood clot in the leg (DVT)	2.9	3.8	6.3	-2.3	2.2	2.3	-2.1	-1.9	-1.6	1.9	1.6	1.1	2.3	2.1	2.1	1.4	1.8	1.9	2.1	2.2	1.8	1.6	1.7	1.3	1.8	0.2	2.3	2.2	1.9	2.0	2.3	2.0	2.5
Medication: Paracetamol	0.9	1.5	4.2	1.4	-0.7	-1.4	0.6	1.6	1.2	-1.1	-1.1	-1.1	-1.8	-1.2	-1.2	-1.4	-0.8	-1.1	-1.3	-1.0	-0.9	-1.2	-1.5	-1.6	-1.1	-1.3	-1.2	-1.0	-1.0	-1.0	-1.2	-1.0	-2.1
Headache pain in last month	0.5	0.9	2.2	-0.4	0.9	0.7	-1.0	1.0	-0.4	1.3	1.4	0.8	0.4	0.9	0.9	-0.5	1.3	0.9	0.4	1.3	1.5	1.4	0.2	-0.3	-0.5	0.8	0.9	0.4	1.3	1.4	1.0	1.4	0.1
Medication for cholesterol, blood pressure or diabetes	2.2	3.6	10.4	-2.0	1.3	1.9	-0.4	-0.9	-1.6	1.6	1.4	2.2	2.2	1.7	1.7	3.2	1.3	1.7	2.1	1.3	1.2	1.5	2.2	3.2	3.2	2.1	1.8	2.3	1.2	1.3	1.6	1.2	2.3
Glaucoma (self-reported)	0.7	0.9	2.7	0.7	-0.3	-0.9	1.4	0.1	1.6	-1.0	-1.2	-1.0	-1.0	-0.8	-0.7	0.0	-1.6	-0.8	-0.4	-0.8	-1.1	-1.1	-1.1	0.2	0.6	-0.0	-0.8	-0.7	-1.1	-1.1	-1.0	-1.1	-0.8
Gout (self-reported)	0.2	0.2	2.3	0.1	-0.4	-0.1	-0.9	-0.5	-0.2	-0.1	-0.0	0.1	0.1	-0.2	-0.1	-1.0	0.0	-0.4	-0.3	-0.2	-0.1	0.1	-0.5	-0.6	-0.7	-1.5	-0.2	0.1	-0.2	-0.2	-0.1	-0.2	0.3
Hypothyroidism/myxoedema (self-reported)	1.2	2.4	4.1	-1.5	2.0	1.5	-1.1	-0.5	-0.9	1.6	1.5	1.2	1.6	1.7	1.7	1.5	1.5	1.8	1.7	1.6	1.6	1.4	1.3	1.9	1.7	1.3	1.7	1.7	1.6	1.5	1.6	1.5	1.4
Medication: Amlodipine	0.7	1.0	2.2	0.0	1.4	0.3	-1.4	0.5	-1.4	1.0	1.4	0.7	0.1	0.7	1.1	0.8	1.5	1.3	0.5	1.4	1.4	1.5	0.6	0.3	0.1	-0.1	0.8	0.1	1.4	1.4	0.9	1.5	-0.4
Medication: Ventolin 100micrograms inhaler	1.0	1.3	3.6	1.8	-1.3	-1.9	0.3	0.9	0.9	-0.7	-0.5	0.8	-1.3	-1.3	-1.1	-1.4	-0.6	-1.1	-1.6	-0.7	-0.6	-0.3	-1.7	-1.4	-1.2	-0.9	-1.4	-1.1	-0.7	-0.8	-1.2	-0.6	-1.1
Birth weight	0.1	0.3	1.8	0.3	-1.4	-0.5	0.5	0.1	0.3	-0.4	-0.3	0.2	-0.4	-0.5	-0.4	-0.8	-0.5	-0.8	-0.7	-0.8	-0.5	-0.3	-0.5	-0.6	-0.8	-0.6	-0.5	-0.0	-0.5	-0.5	-0.5	-0.5	-0.5
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.7	-0.2	0.4	0.1	-0.5	-0.8	-0.3	-0.1	-0.1	-0.5	0.1	-0.0	0.0	-0.2	-0.1	0.1	-0.3	0.1	-0.0	-0.2	0.0	-0.0	-0.3	-0.1	-0.0	-0.5	0.1	-0.0	-0.0	-0.0	0.2
High blood pressure (siblings)	0.7	1.0	2.1	-1.1	1.4	1.1	-0.6	0.1	-1.0	1.0	0.9	0.2	0.9	1.1	1.0	0.7	1.1	1.0	1.2	1.2	1.0	0.9	1.3	0.8	0.7	1.4	1.1	0.8	0.9	1.0	1.1	1.0	0.9
Forced vital capacity (FVC), Best measure	1.1	4.1	10.3	1.8	-2.3	-2.0	2.3	3.2	2.7	-2.1	-1.9	-1.7	-1.5	-2.1	-2.3	-2.0	-1.6	-2.2	-1.9	-2.2	-2.0	-1.9	-2.1	-1.6	-2.1	-0.7	-2.0	-1.6	-2.0	-1.9	-2.0	-1.9	-1.4
Body fat percentage	0.2	0.9	7.0	-1.5	0.4	1.4	-1.2	-2.6	-1.5	0.6	0.3	0.4	1.1	0.9	0.8	0.2	0.4	0.5	0.9	0.4	0.3	0.3	1.1	0.5	0.6	-0.8	1.1	1.4	0.4	0.5	0.8	0.4	1.2
Leg fat percentage (right)	0.6	2.2	7.9	-2.1	1.2	2.0	-1.9	-2.8	-2.0	1.3	1.1	0.7	1.6	1.5	1.5	0.8	1.1	1.3	1.5	1.2	1.1	1.0	1.7	0.8	1.0	0.2	1.7	1.9	1.1	1.2	1.4	1.1	1.7
Arm fat-free mass (right)	0.4	1.8	8.5	-2.4	0.2	2.0	-0.8	-2.9	-1.0	0.6	0.1	0.3	2.2	1.3	1.1	0.9	0.2	0.4	2.0	-0.1	0.1	0.1	1.5	1.7	1.9	0.2	1.7	1.8	-0.0	0.1	1.0	-0.0	2.4
Exposure to tobacco smoke outside home	6.5	8.7	17.0	-3.3	3.2	3.1	-3.6	-4.1	-3.0	2.8	2.4	1.7	3.5	3.0	2.9	3.0	2.4	2.8	3.0	2.7	2.6	2.4	3.1	3.4	3.1	2.1	3.2	2.9	2.4	2.6	3.0	2.5	3.4
Comparative body size at age 10	1.3	3.5	7.5	1.1	-2.5	-1.2	2.7	0.9	1.9	-2.1	-2.3	-2.1	-1.1	-1.7	-2.1	-0.8	-2.1	-2.2	-1.2	-2.6	-2.4	-2.4	-1.1	-1.1	-0.6	-0.6	-1.6	-1.4	-2.5	-2.5	-2.0	-2.6	-0.9
Number of full brothers	3.3	4.2	7.5	-2.0	2.5	2.1	-2.2	-1.9	-2.4	2.0	1.7	1.9	2.0	2.2	2.2	1.6	1.5	2.1	2.3	2.0	1.7	1.7	2.0	2.3	2.1	1.5	2.2	2.7	1.8	1.9	2.1	1.8	2.0
Worry too long after embarrassment	0.4	0.6	1.8	0.1	1.3	0.0	-1.1	-0.3	-0.7	1.0	1.1	1.1	-0.3	0.4	0.7	1.0	0.9	0.9	0.4	1.2	1.1	1.2	0.2	0.9	0.7	0.1	0.3	0.4	1.0	1.0	0.6	1.0	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.8	-0.1	0.2	0.1	0.1	0.2	0.9	0.4	0.3	0.5	-0.0	0.3	0.2	-0.7	0.3	0.2	-0.1	0.4	0.4	0.3	-0.3	-0.3	-0.4	-0.5	0.1	-0.0	0.4	0.4	0.4	0.4	-0.1
Wheeze or whistling in the chest in last year	1.5	2.6	7.8	-1.5	1.2	1.4	-1.9	-2.1	-1.9	1.8	1.8	2.8	1.2	1.6	1.7	0.5	1.8	1.6	1.2	1.6	1.7	1.8	1.4	0.9	0.8	0.8	1.6	1.8	1.8	1.7	1.6	1.8	1.1
Number of children fathered	1.7	1.9	3.6	-1.5	1.2	1.6	-0.3	-1.7	-1.2	1.3	1.3	0.3	1.6	1.5	1.5	0.8	1.7	1.3	1.3	1.6	1.2	1.3	1.3	0.5	0.5	1.7	1.5	1.5	1.6	1.6	1.6	1.6	1.9
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.6	2.6	0.6	-1.4	-0.8	1.5	0.6	1.0	-1.4	-1.6	-1.4	-0.9	-1.2	-1.2	-1.4	-1.5	-1.5	-1.2	-1.6	-1.5	-1.6	-0.9	-0.9	-1.2	0.2	-1.1	-1.1	-1.5	-1.5	-1.3	-1.6	-0.7
Age at first live birth	1.7	3.0	7.2	2.3	-2.2	-2.3	1.0	2.7	2.1	-1.3	-0.8	-0.3	-1.9	-1.7	-1.8	-1.8	-1.2	-1.4	-2.3	-1.2	-0.9	-0.8	-2.0	-1.8	-2.4	-1.9	-2.1	-2.0	-0.9	-0.9	-1.7	-0.9	-2.2
Pulse wave peak to peak time	0.4	0.5	3.1	-0.6	0.6	0.5	0.4	-0.1	-0.1	0.7	0.6	1.1	0.7	0.6	0.6	0.6	0.5	0.6	0.7	0.7	0.6	0.7	0.4	0.9	1.0	1.8	0.6	0.8	0.6	0.6	0.6	0.6	0.8
Health satisfaction	1.5	2.0	3.4	-1.3	1.8	1.4	-1.6	-0.6	-1.3	1.7	1.7	1.9	0.9	1.4	1.7	0.9	1.6	1.7	1.2	1.6	1.8	1.6	0.9	0.9	1.3	0.8	1.5	1.5	1.6	1.5	1.4	1.5	0.6
Shortness of breath walking on level ground	0.6	0.7	2.7	-1.6	0.7	1.4	0.0	-1.4	-0.8	0.6	0.2	0.9	0.5	1.0	0.8	0.3	0.1	0.5	1.0	0.4	0.2	0.2	1.1	0.8	1.2	0.5	1.2	1.2	0.3	0.4	0.8	0.3	0.4
Qualifications: College or University degree	1.5	4.6	6.2	2.2	-2.5	-2.2	1.4	1.3	2.4	-2.3	-2.2	-1.5	-1.8	-2.4	-2.4	-1.9	-2.1	-2.4	-2.5	-2.3	-2.2	-2.1	-2.3	-1.9	-1.7	-2.2	-2.4	-2.2	-2.3	-2.2	-2.3	-2.2	-1.5
Eye problems/disorders: None of the above	3.1	3.6	5.6	-1.5	1.8	1.7	-2.0	-0.3	-2.1	2.1	2.3	1.7	1.9	2.1	2.0	1.4	2.2	2.1	1.6	2.1	2.2	2.2	2.1	1.5	0.6	1.4	1.7	1.5	2.4	2.4	2.2	2.4	1.8
Mouth/teeth dental problems: Loose teeth	1.3	1.5	2.8	-1.6	1.5	1.7	-0.1	0.1	-1.1	1.2	1.0	0.5	1.6	1.4	1.3	0.8	1.2	1.3	1.4	1.2	1.2	1.0	1.2	1.0	1.2	1.6	1.6	1.2	1.1	1.2	1.5	1.1	1.5
Emphysema/chronic bronchitis	0.1	0.1	2.6	-0.1	-0.4	-0.0	0.1	-1.6	-0.2	-0.3	-0.1	-0.2	0.0	-0.3	-0.0	0.2	-0.4	-0.1	-0.3	-0.3	-0.1	-0.1	-0.3	0.0	0.4	-0.2	0.1	-0.2	-0.3	-0.3	-0.3	-0.2	-0.1
Medication for pain relief, constipation, heartburn	0.6	1.1	5.4	-0.2	0.6	0.3	-1.3	-0.3	-1.1	1.2	1.5	2.3	0.8	0.7	1.0	0.7	1.2	1.1	0.5	1.1	1.2	1.7	0.4	0.9	0.2	1.2	0.5	0.7	1.4	1.2	0.8	1.3	0.8
Neck or shoulder pain in last month	5.0	7.2	10.4	-3.2	2.9	3.2	-2.3	-2.5	-2.5	2.5	2.3	1.4	2.8	3.0	2.9	2.9	2.4	2.9	3.0	2.7	2.4	2.2	3.0	2.7	3.0	1.9	3.1	2.6	2.5	2.5	3.0	2.5	2.7
Medication: Blood pressure	0.1	0.3	1.2	0.2	0.5	0.1	-0.6	-0.0	-0.4	0.3	0.5	-0.5	-0.4	0.1	0.3	-0.9	0.6	0.3	-0.1	0.6	0.6	0.4	-0.3	-1.1	-1.0	-0.4	0.2	-0.3	0.6	0.6	0.3	0.6	-0.6
Angina (self-reported)	0.2	0.2	0.9	0.5	0.8	-0.2	0.2	0.7	0.5	0.2	0.2	-0.4	-0.5	0.0	-0.0	-0.9	0.6	0.1	-0.3	0.5	0.3	0.2	-0.3	-0.8	-0.9	0.3	-0.1	-0.2	0.4	0.3	0.1	0.3	-0.4
Migraine (self-reported)	0.7	0.9	2.8	0.1	1.0	0.3	-1.7	-0.2	-1.0	1.1	1.3	1.4	0.0	0.8	1.0	0.1	1.3	1.0	0.2	1.2	1.3	1.4	0.5	0.1	-0.0	0.0	0.5	0.4	1.3	1.3	0.9	1.3	-0.2
Medication: Ibuprofen	0.7	0.8	2.2	-1.2	0.6	1.4	-0.1	-1.2	-0.5	0.8	0.5	-0.1	1.1	1.3	0.8	0.9	0.6	0.7	1.4	0.6	0.5	0.4	1.5	0.7	1.2	1.2	1.2	1.0	0.5	0.6	1.0	0.5	1.1
Medication: Allopurinol	0.1	0.2	1.5	-0.6	-0.4	0.6	-0.1	-0.7	-0.2	0.1	-0.0	0.1	0.8	0.2	0.1	-0.6	-0.1	-0.2	0.0	-0.2	-0.1	0.0	0.1	-0.1	-0.5	-0.2	0.2	0.3	-0.1	-0.1	0.2	-0.1	1.2
Medication: Omeprazole	0.4	0.4	2.1	-1.0	0.2	0.7	1.1	-1.2	-0.2	-0.3	-0.6	-1.3	0.3	0.2	0.1	1.1	-0.5	0.0	0.7	-0.3	-0.5	-0.8	0.6	0.4	1.4	0.2	0.4	0.1	-0.6	-0.4	0.0	-0.6	0.4
Medication: Seretide 50 evohaler	4.0	4.6	6.2	1.8	-1.8	-2.1	2.4	1.2	2.1	-2.3	-2.3	-2.1	-2.5	-2.2	-2.1	-2.3	-2.5	-2.3	-2.3	-2.1	-2.2	-2.3	-2.3	-2.1	-1.9	-1.1	-2.0	-1.9	-2.1	-2.2	-2.3	-2.1	-2.4
Mean time to correctly identify matches	2.3	4.5	8.0	2.1	-1.5	-2.1	2.2	2.8	2.2	-1.9	-1.8	-2.7	-2.7	-2.1	-2.2	-1.8	-1.4	-2.0	-2.0	-1.9	-1.7	-1.9	-1.8	-2.6	-2.3	-1.8	-2.3	-2.1	-1.9	-2.0	-2.0	-1.9	-2.8
Heart disease (mother)	2.6	3.2	4.7	-1.7	1.9	1.8	-1.1	-0.6	-2.0	1.9	1.8	1.4	2.0	2.0	1.9	1.4	1.7	1.8	2.0	1.7	1.8	1.8	2.0	2.0	1.4	2.0	1.9	1.8	1.7	1.7	1.9	1.7	2.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	2.1	0.1	-0.2	-0.3	0.7	-1.4	-0.3	-0.4	-0.4	-0.6	-0.1	-0.2	-0.3	0.7	-0.5	-0.3	0.3	-0.3	-0.5	-0.6	0.5	0.2	0.6	0.3	-0.3	-0.3	-0.5	-0.5	-0.3	-0.5	0.2
Whole body fat mass	0.4	1.5	8.7	-2.0	0.6	1.7	-1.5	-2.9	-1.7	0.9	0.5	0.6	1.5	1.2	1.1	0.5	0.6	0.7	1.4	0.5	0.4	0.5	1.4	1.0	1.1	-0.6	1.4	1.9	0.5	0.6	1.1	0.5	1.7
Leg fat mass (right)	0.8	3.2	11.5	-2.6	1.3	2.4	-2.1	-3.4	-2.3	1.5	1.1	1.0	2.2	1.9	1.8	1.0	1.1	1.4	2.0	1.1	1.1	1.1	2.0	1.5	1.6	0.3	2.1	2.4	1.1	1.2	1.7	1.1	2.3
Arm predicted mass (right)	0.4	2.2	9.0	-2.6	0.2	2.2	-0.9	-3.0	-1.2	0.8	0.3	0.5	2.3	1.5	1.3	1.1	0.4	0.6	2.1	0.0	0.2	0.3	1.6	1.8	2.0	0.3	1.9	2.0	0.1	0.3	1.2	0.1	2.5
Pulse rate, automated reading	1.1	3.7	7.1	2.0	-1.4	-2.1	1.3	1.6	1.8	-2.0	-1.9	-1.9	-2.0	-2.0	-2.1	-2.1	-1.9	-1.9	-2.0	-1.6	-1.9	-2.0	-1.8	-2.0	-2.2	-2.7	-2.2	-2.1	-1.7	-1.8	-1.9	-1.7	-1.7
Alcohol intake frequency.	5.0	11.7	17.8	-4.0	3.1	3.9	-2.9	-2.6	-3.5	3.6	3.1	3.7	3.3	3.8	3.7	3.3	2.7	3.4	3.9	3.1	3.1	3.1	3.8	3.9	3.6	2.9	3.8	4.2	3.0	3.2	3.6	3.1	3.0
Comparative height size at age 10	0.0	0.2	1.6	-0.3	-1.3	0.2	-0.1	-0.9	-0.4	-0.2	-0.2	0.8	0.4	-0.1	-0.0	-0.1	-0.3	-0.5	0.1	-0.8	-0.4	0.0	-0.1	0.6	0.1	-0.2	-0.1	0.4	-0.5	-0.5	-0.2	-0.5	0.6
Number of full sisters	4.1	5.0	6.5	2.3	-1.9	-2.3	1.7	1.7	2.4	-2.4	-2.4	-2.2	-2.2	-2.3	-2.5	-2.3	-1.9	-2.5	-2.2	-2.3	-2.3	-2.4	-2.2	-2.5	-2.3	-1.8	-2.3	-2.3	-2.3	-2.4	-2.3	-2.3	-1.9
Suffer from ‘nerves’	7.3	11.4	20.1	-2.5	3.6	2.7	-4.3	-2.6	-3.3	3.8	3.8	4.5	2.5	3.3	3.6	3.1	3.7	3.7	3.1	3.8	3.8	4.0	2.8	3.0	3.0	2.3	3.2	3.3	3.6	3.7	3.4	3.6	2.2
Overall health rating	4.1	8.9	12.4	-3.4	3.0	3.5	-2.3	-2.3	-3.1	3.1	2.8	3.2	3.0	3.2	3.3	2.4	2.8	3.2	2.9	2.9	2.9	2.7	3.0	3.0	2.7	2.5	3.4	3.4	2.9	3.0	3.2	2.9	2.7
Chest pain or discomfort	2.8	4.0	7.2	-2.0	2.7	1.9	-1.3	-0.7	-1.5	2.3	2.2	1.9	1.7	2.1	2.2	1.4	2.5	2.4	2.0	2.3	2.3	2.1	1.6	1.6	1.6	2.0	2.1	2.0	2.2	2.2	2.2	2.2	1.5
Had major operations	0.3	0.4	1.7	0.4	-0.3	-0.4	1.0	0.4	0.8	-0.6	-0.6	0.1	-1.1	-0.5	-0.5	-0.0	-0.8	-0.4	-0.3	-0.5	-0.7	-0.5	-0.8	-0.0	0.4	0.7	-0.4	-0.1	-0.5	-0.5	-0.6	-0.5	-1.3
Age at last live birth	1.8	2.6	5.1	1.9	-2.2	-2.0	0.9	2.2	1.9	-1.2	-0.9	-0.2	-1.8	-1.6	-1.6	-1.9	-1.4	-1.5	-2.0	-1.3	-1.0	-0.8	-1.8	-1.7	-2.3	-1.7	-2.0	-1.9	-1.0	-1.0	-1.6	-1.0	-2.0
Family relationship satisfaction	2.2	2.7	6.9	-1.5	1.4	1.5	-1.9	-1.4	-1.5	1.8	1.6	2.6	1.8	1.5	1.8	1.7	1.4	1.8	1.7	1.6	1.8	1.7	1.1	1.7	2.2	0.6	1.7	1.5	1.5	1.5	1.5	1.5	1.7
Leg pain on walking	0.1	0.2	1.0	-0.3	-0.1	0.4	0.4	0.9	-0.3	0.4	0.5	1.0	-0.1	0.3	0.4	-0.5	0.5	0.2	-0.0	0.2	0.4	0.4	-0.0	-0.2	-0.3	0.7	0.4	0.5	0.4	0.4	0.3	0.4	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.7	0.7	-0.4	-0.5	-0.1	0.5	0.8	-0.2	0.0	0.1	-0.7	-0.3	-0.2	-1.1	-0.2	-0.2	-0.8	0.0	-0.1	0.1	-0.7	-1.0	-1.1	-1.3	-0.5	-0.5	0.2	0.1	-0.3	0.2	-0.7
Commuting to job workplace: Car/motor vehicle	1.7	1.9	5.8	-0.5	1.4	0.9	-2.4	-1.4	-1.9	1.4	1.5	1.8	1.5	0.9	1.3	1.0	1.4	1.5	0.6	1.6	1.6	1.7	0.7	1.1	0.8	0.8	1.2	1.0	1.6	1.6	1.2	1.7	1.6
Illness, injury, bereavement, stress in last 2 years	1.2	1.4	3.9	1.7	-1.2	-1.5	1.3	1.7	2.0	-1.0	-0.8	-0.6	-1.2	-1.3	-1.3	-0.8	-0.8	-1.0	-1.4	-0.9	-0.7	-0.7	-1.8	-1.1	-0.8	-0.3	-1.2	-1.7	-0.9	-0.9	-1.3	-0.9	-1.4
Medication: Aspirin	0.9	1.2	3.7	0.9	-0.4	-0.8	0.8	0.4	0.8	-1.2	-1.3	-1.9	-1.2	-0.9	-1.1	-1.0	-1.1	-1.1	-0.9	-1.0	-1.1	-1.4	-0.7	-1.0	-0.9	-1.6	-0.9	-1.0	-1.2	-1.2	-1.0	-1.2	-1.1
Supplements: Vitamin C	0.1	0.2	0.6	0.0	0.3	0.1	0.0	0.8	0.5	0.5	0.6	0.1	0.3	0.4	0.3	-0.6	0.5	0.3	0.3	0.6	0.5	0.5	0.0	-0.2	-0.3	0.3	0.1	0.2	0.5	0.6	0.5	0.5	0.4
Knee pain experienced in last month	0.5	0.7	2.4	-1.0	0.8	0.9	-0.9	-1.0	-1.5	0.9	0.8	0.8	0.7	0.8	0.9	0.5	0.7	0.8	0.7	0.8	0.9	0.8	1.0	0.6	0.6	0.8	1.0	0.7	0.8	0.8	0.9	0.9	0.6
Hypertension (Self-reported)	0.5	1.4	6.1	1.4	0.5	-1.0	-0.2	1.8	0.4	0.2	0.8	-0.8	-1.4	-0.2	0.0	-2.1	0.8	0.3	-1.0	0.9	0.9	0.5	-1.3	-2.4	-2.5	-2.0	-0.4	-0.9	1.0	0.8	0.1	1.0	-1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	3.6	0.2	-1.0	-0.3	1.5	-0.3	0.6	-1.1	-1.2	-1.9	-0.8	-0.7	-0.8	-0.5	-1.2	-1.0	-0.6	-1.1	-1.1	-1.4	-0.3	-0.7	-0.2	-0.2	-0.6	-0.8	-1.3	-1.1	-0.9	-1.2	-0.8
Illnesses of father: Heart disease	0.3	0.4	2.8	1.1	0.7	-0.7	-0.5	1.7	-0.6	-0.0	-0.0	0.3	-0.8	-0.4	-0.1	-1.2	-0.0	-0.1	-0.8	0.2	0.1	0.1	-0.6	-0.2	-1.0	0.0	-0.3	-0.2	0.2	0.0	-0.3	0.2	-0.7
Illnesses of siblings: Diabetes	1.9	2.3	11.1	-2.3	1.2	2.0	-0.3	-3.3	-2.0	0.8	0.3	-0.3	1.9	1.5	1.4	1.5	0.5	1.0	2.0	0.7	0.4	0.3	2.0	1.6	2.0	0.5	1.7	2.0	0.4	0.5	1.2	0.4	2.4
Smoking status: Previous	0.2	0.3	0.8	-0.6	0.5	0.6	-0.5	0.0	-0.0	0.6	0.5	-0.4	0.3	0.7	0.5	-0.6	0.9	0.4	0.5	0.5	0.7	0.4	0.2	-0.5	-0.3	-0.8	0.6	0.5	0.5	0.6	0.6	0.5	0.2
Forced expiratory volume in 1-second (FEV1), predicted	1.4	2.9	6.4	2.2	-1.7	-2.2	1.5	1.4	1.8	-1.6	-1.3	-1.8	-1.6	-1.7	-1.8	-2.2	-1.1	-1.7	-2.0	-1.4	-1.4	-1.4	-2.0	-2.3	-2.5	-1.6	-1.8	-1.6	-1.1	-1.2	-1.6	-1.1	-1.4
Whole body fat-free mass	0.3	1.5	8.3	-2.2	-0.4	1.6	-0.7	-2.9	-1.0	0.4	-0.0	0.6	1.9	1.1	0.9	1.0	0.0	0.2	1.7	-0.4	-0.2	0.0	1.3	1.7	1.8	-0.2	1.4	1.6	-0.2	-0.1	0.7	-0.2	2.1
Leg fat-free mass (right)	0.3	1.5	7.3	-2.1	-0.3	1.7	-0.7	-2.7	-1.1	0.6	0.1	0.8	1.7	1.2	1.0	0.7	0.1	0.3	1.7	-0.2	-0.1	0.2	1.3	1.6	1.6	-0.5	1.4	1.9	-0.0	0.1	0.8	-0.0	1.9
Arm fat percentage (left)	0.2	0.9	8.6	-1.7	0.0	1.4	-0.8	-2.9	-1.3	0.3	-0.1	0.3	1.1	0.8	0.7	0.4	-0.2	0.3	0.9	-0.0	-0.2	-0.1	1.1	0.9	1.0	-0.6	1.1	1.5	-0.0	0.1	0.6	-0.0	1.2
Average weekly red wine intake	3.3	4.8	7.8	2.2	-2.4	-2.1	2.0	1.9	1.9	-2.2	-2.3	-1.8	-2.1	-2.3	-2.2	-2.6	-1.9	-2.5	-2.3	-2.3	-2.2	-2.1	-2.3	-2.8	-2.3	-0.8	-2.1	-2.4	-2.3	-2.2	-2.2	-2.2	-1.9
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.2	0.8	0.2	-0.6	-1.0	1.1	0.3	0.3	0.6	1.1	-0.6	-0.3	-0.1	-0.7	0.5	0.2	-0.6	0.3	0.6	0.6	-0.9	-0.4	-0.8	-0.7	-0.4	-0.1	0.5	0.3	-0.1	0.4	-0.8
Mood swings	1.3	2.4	4.7	-1.4	2.0	1.2	-2.2	-1.0	-1.5	2.0	2.0	1.1	1.0	1.6	1.8	-0.1	2.1	1.7	1.2	1.9	2.1	1.9	1.0	0.5	0.1	1.0	1.6	1.4	1.9	1.9	1.6	1.9	0.8
Loneliness, isolation	6.1	8.4	14.4	-2.1	2.6	2.4	-3.6	-1.4	-2.9	3.3	3.5	3.8	2.6	2.8	3.1	2.3	3.1	3.3	2.6	3.3	3.4	3.6	2.3	2.5	2.0	1.6	2.7	2.6	3.4	3.3	2.9	3.4	2.2
Long-standing illness, disability or infirmity	1.1	1.6	3.0	-1.3	1.4	1.2	-1.7	-1.2	-1.6	1.4	1.2	1.7	0.6	1.4	1.5	0.9	1.1	1.4	1.3	1.2	1.3	1.2	1.1	1.2	1.4	-0.2	1.4	1.6	1.2	1.2	1.3	1.1	0.3
Ever had bowel cancer screening	0.4	0.5	2.2	0.8	-0.5	-0.8	0.0	0.4	0.4	-0.3	-0.3	-0.3	-1.0	-0.5	-0.5	-0.7	-0.2	-0.4	-0.7	-0.2	-0.2	-0.3	-0.6	-1.4	-1.0	-1.5	-0.8	-0.8	-0.3	-0.3	-0.5	-0.3	-1.1
Diabetes diagnosed by doctor	0.5	0.8	3.6	0.1	-0.7	-0.3	1.4	-0.6	0.7	-1.0	-1.2	-1.9	-0.7	-0.5	-0.6	-1.5	-1.4	-1.0	-0.4	-0.8	-1.2	-1.3	-0.5	-0.8	-1.0	-0.7	-0.5	-0.6	-1.0	-0.8	-0.7	-0.9	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.9	0.6	-0.0	-0.7	-0.2	-0.1	1.0	-0.9	-0.9	-1.4	-0.6	-0.7	-0.7	-0.5	-0.9	-0.7	-0.5	-0.6	-0.8	-0.9	-1.0	-0.2	-0.2	-0.3	-0.6	-0.3	-0.7	-0.8	-0.7	-0.7	-0.6
Friendships satisfaction	1.5	1.9	5.8	-1.1	1.3	1.2	-2.1	-0.8	-1.1	1.6	1.4	2.4	1.3	1.2	1.5	0.9	1.4	1.4	1.1	1.4	1.6	1.7	0.6	1.3	1.6	0.6	1.3	1.0	1.3	1.3	1.3	1.3	1.3
Qualifications: nursing, teaching	0.5	0.8	1.6	0.3	-0.9	-0.5	0.9	0.5	1.1	-1.0	-1.1	-0.6	-0.5	-1.0	-1.0	-0.3	-1.2	-1.1	-0.8	-1.2	-1.1	-1.0	-0.9	-0.3	-0.1	-0.9	-0.8	-0.9	-1.2	-1.1	-1.0	-1.2	-0.5
Commuting to job workplace: Walk	1.5	1.6	2.8	1.1	-1.7	-1.2	1.6	1.3	1.4	-1.1	-1.1	-0.7	-1.5	-1.2	-1.4	-1.3	-1.0	-1.3	-1.1	-1.5	-1.2	-1.1	-1.2	-1.5	-1.2	-0.4	-1.3	-1.0	-1.3	-1.3	-1.3	-1.3	-1.6
Eye problems/disorders: Cataract	1.5	1.7	3.0	0.9	-1.5	-1.0	1.4	0.7	1.4	-1.5	-1.6	-1.1	-1.2	-1.4	-1.5	-0.5	-1.5	-1.5	-1.1	-1.7	-1.6	-1.6	-1.3	-0.7	-0.3	-0.8	-1.2	-0.7	-1.7	-1.7	-1.5	-1.7	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.8	-0.7	0.7	0.8	-0.2	-0.3	-0.3	0.7	0.7	-0.0	0.9	0.8	0.7	0.6	0.5	0.8	0.7	0.9	0.7	0.6	0.6	0.7	0.4	-0.1	0.7	0.5	0.8	0.8	0.7	0.8	0.9
Medication for cholesterol	0.3	0.5	2.2	-0.8	-0.6	0.4	0.5	-0.8	0.1	-0.4	-0.8	0.1	0.6	-0.0	-0.2	1.3	-0.8	-0.3	0.6	-0.7	-0.8	-0.6	0.6	1.0	1.5	0.3	-0.1	0.4	-0.8	-0.8	-0.3	-0.9	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.6	-0.6	0.8	0.6	0.2	1.6	0.6	0.8	0.8	0.3	0.8	0.9	0.6	0.4	1.0	0.8	0.8	0.7	0.8	0.7	0.4	0.5	0.5	1.6	0.6	1.0	0.8	0.7	0.8	0.7	0.8
Back pain experienced in last month	3.0	4.4	6.0	-1.6	2.4	1.9	-2.4	-1.2	-2.1	2.3	2.3	1.3	1.9	2.3	2.2	1.5	2.3	2.4	2.1	2.4	2.3	2.2	2.0	1.5	1.4	1.6	2.3	2.4	2.4	2.4	2.4	2.4	1.8
Mineral and other dietary supplements	1.3	1.7	6.2	-1.8	1.1	1.3	-0.7	-2.5	-1.8	0.9	0.7	-0.3	1.1	1.4	1.3	1.5	0.7	0.8	1.8	0.7	0.6	0.7	2.0	1.4	1.4	2.4	1.4	1.6	0.5	0.7	1.1	0.5	1.2
Breast cancer (self-reported)	0.7	0.8	4.6	-0.9	0.3	1.1	-0.2	0.3	-0.6	0.9	0.8	1.8	0.7	0.9	0.8	0.6	0.8	0.8	0.9	0.5	0.7	1.0	1.0	0.7	0.8	2.2	0.9	1.0	0.7	0.7	0.8	0.7	0.5
Asthma (self-reported)	0.1	0.2	2.2	-0.0	-0.3	-0.1	-0.1	-0.1	-0.0	0.5	0.5	1.5	-0.1	0.1	0.2	-0.6	0.5	0.1	-0.4	0.3	0.5	0.5	-0.5	-0.3	-0.4	0.3	0.2	0.1	0.5	0.5	0.2	0.5	-0.2
Osteoporosis (self-reported)	1.5	1.8	3.8	-1.7	1.4	1.6	-0.8	-0.6	-1.4	1.3	1.0	1.4	1.5	1.5	1.3	1.4	1.1	1.2	1.6	1.0	0.9	1.0	1.5	1.9	1.5	1.5	1.3	1.9	1.0	1.0	1.3	0.9	1.8
Osteoarthritis (self-reported)	1.2	1.6	4.3	0.7	-1.7	-0.9	1.3	0.1	1.0	-1.3	-1.4	-0.3	-1.7	-1.2	-1.3	0.6	-1.8	-1.3	-0.7	-1.8	-1.5	-1.4	-0.5	0.1	0.5	0.1	-1.2	-1.1	-1.7	-1.6	-1.6	-1.7	-2.1
Medication: Aspirin	1.1	1.4	4.9	1.1	-0.4	-0.9	1.0	0.5	0.9	-1.4	-1.5	-2.2	-1.3	-1.0	-1.3	-0.8	-1.3	-1.2	-0.9	-1.1	-1.3	-1.6	-0.7	-1.0	-0.9	-1.6	-1.0	-1.2	-1.3	-1.3	-1.1	-1.3	-1.3
Medication: Gliclazide	1.9	2.2	8.9	0.6	-1.6	-0.8	3.0	0.9	1.1	-1.7	-1.9	-2.3	-1.2	-1.3	-1.4	-1.0	-1.7	-1.7	-0.7	-1.8	-1.9	-2.0	-0.6	-1.2	-1.0	-0.1	-1.2	-1.1	-1.8	-1.8	-1.4	-1.8	-0.9
Illnesses of father: None of the above (group 1)	0.2	0.2	2.6	-0.1	-0.2	-0.3	-0.7	-1.4	-0.1	0.0	0.4	-0.6	0.1	-0.2	0.1	0.5	0.4	0.1	-0.1	0.3	0.2	0.3	-0.1	-0.3	-0.1	-1.6	-0.4	-0.7	0.1	0.1	0.1	0.2	0.4
Smoking status: Current	0.3	0.5	2.5	-1.0	0.8	0.9	-1.1	-1.4	-1.6	0.4	0.3	0.2	0.9	0.5	0.8	0.8	0.4	0.7	0.5	0.6	0.4	0.4	0.9	0.5	0.7	0.6	0.8	0.3	0.5	0.5	0.6	0.4	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	10.4	1.3	-1.8	-1.3	1.3	3.2	1.8	-1.4	-1.2	-0.3	-1.4	-1.6	-1.5	-1.7	-0.8	-1.5	-1.8	-1.7	-1.2	-1.1	-1.8	-1.4	-1.6	-1.1	-1.4	-1.0	-1.2	-1.2	-1.5	-1.2	-1.8
Whole body water mass	0.3	1.5	8.2	-2.2	-0.4	1.6	-0.7	-2.9	-0.9	0.4	-0.0	0.5	1.9	1.1	0.9	1.0	-0.0	0.2	1.7	-0.4	-0.2	0.0	1.3	1.7	1.9	-0.2	1.4	1.6	-0.2	-0.1	0.7	-0.3	2.1
Leg predicted mass (right)	0.3	1.5	7.5	-2.2	-0.2	1.7	-0.7	-2.7	-1.2	0.6	0.2	0.8	1.8	1.2	1.1	0.8	0.1	0.3	1.7	-0.2	-0.1	0.2	1.3	1.7	1.6	-0.4	1.5	1.9	0.0	0.1	0.9	0.0	2.0
Arm fat mass (left)	0.4	1.7	11.5	-2.4	0.2	2.0	-1.1	-3.4	-1.5	0.6	0.1	0.6	1.7	1.2	1.1	0.7	0.1	0.5	1.5	0.1	0.0	0.1	1.5	1.5	1.6	-0.2	1.5	2.0	0.1	0.2	0.9	0.1	1.9
Number of self-reported non-cancer illnesses	0.3	0.6	2.0	-0.0	0.9	-0.0	-1.1	-1.2	-0.6	0.7	0.9	0.1	-0.6	0.4	0.6	0.1	0.8	1.0	-0.1	1.2	1.1	0.7	-0.1	-0.6	-0.0	-1.4	0.2	-0.6	1.0	1.0	0.6	1.0	-0.9
Average weekly champagne plus white wine intake	0.9	1.3	2.4	0.7	-1.5	-1.0	1.4	-0.5	0.5	-1.3	-1.4	-1.2	-0.9	-1.1	-1.3	-0.3	-1.4	-1.3	-0.8	-1.5	-1.5	-1.5	-0.5	-0.6	-0.3	-0.7	-1.1	-0.9	-1.5	-1.5	-1.3	-1.5	-0.7
Miserableness	1.0	1.8	3.8	-1.1	1.6	1.1	-1.4	-1.1	-1.9	1.6	1.4	1.4	0.6	1.5	1.5	0.9	1.3	1.3	1.3	1.3	1.5	1.4	1.6	1.3	0.9	1.9	1.3	1.5	1.3	1.3	1.2	1.3	0.3
Guilty feelings	0.4	0.6	2.5	-0.0	0.7	-0.1	-1.0	-1.6	-0.7	0.8	1.1	1.1	-0.2	0.4	0.8	0.7	0.8	0.8	0.1	1.1	1.0	1.2	0.1	0.1	0.6	0.1	0.4	0.2	1.0	0.9	0.5	1.0	-0.3
Wears glasses or contact lenses	1.4	1.6	5.6	1.1	-1.4	-1.0	2.0	2.4	1.4	-1.3	-1.3	-1.0	-1.1	-1.2	-1.3	-0.5	-1.5	-1.3	-0.9	-1.5	-1.3	-1.2	-1.0	-0.2	-0.8	0.5	-1.3	-0.9	-1.4	-1.4	-1.4	-1.4	-1.1
Ever taken oral contraceptive pill	0.6	0.7	1.2	0.5	-0.9	-0.9	1.0	0.4	0.9	-0.8	-0.9	-0.9	-0.7	-0.8	-0.7	-1.1	-0.9	-0.9	-0.8	-1.0	-0.8	-0.9	-1.0	-0.9	-0.6	0.0	-0.6	-0.9	-0.9	-1.0	-0.9	-1.0	-0.8
Hearing aid user	2.2	2.5	6.4	-2.0	1.1	1.7	-0.6	-1.3	-1.3	1.5	1.2	1.3	1.6	1.9	1.5	2.5	1.0	1.6	2.1	1.2	1.2	1.1	2.3	2.1	2.5	1.8	1.5	1.4	1.1	1.2	1.6	1.0	1.6
Mother’s age at death	0.3	0.4	1.5	0.6	-0.2	-0.6	0.8	1.2	0.4	-0.7	-0.7	-1.0	-0.6	-0.7	-0.6	0.4	-0.7	-0.6	-0.3	-0.6	-0.6	-0.7	-0.2	-0.1	0.3	-0.6	-0.6	-0.5	-0.8	-0.7	-0.6	-0.7	-0.7
Financial situation satisfaction	0.9	1.1	2.2	-0.8	1.2	0.9	-1.3	-0.8	-0.7	1.1	1.2	1.3	0.8	0.9	1.2	1.1	1.0	1.3	0.8	1.2	1.3	1.3	0.4	1.4	1.5	0.6	1.1	0.8	1.1	1.1	1.0	1.1	0.6
Tinnitus: Yes, now most or all of the time	0.9	1.1	5.4	-1.3	0.4	1.2	0.1	-1.7	-1.1	0.3	0.3	0.3	1.2	0.6	0.7	2.3	0.3	0.7	1.1	0.3	0.3	0.3	1.2	1.8	2.3	1.3	0.9	0.9	0.1	0.3	0.6	0.2	1.2
Commuting to job workplace: Public transport	0.7	0.8	1.7	0.5	-1.3	-0.7	1.1	0.3	1.1	-0.9	-1.0	-0.7	-0.8	-0.8	-1.0	-0.6	-1.1	-1.0	-0.6	-1.1	-1.1	-1.1	-0.6	-0.9	-0.4	-0.6	-0.8	-1.2	-1.1	-1.0	-0.9	-1.1	-0.8
Eye problems/disorders: Glaucoma	0.5	0.6	2.5	0.2	-0.3	-0.3	1.6	0.1	1.5	-0.7	-0.9	-0.8	-0.5	-0.4	-0.4	0.2	-1.5	-0.6	0.0	-0.6	-0.8	-0.9	-0.6	0.6	0.9	0.5	-0.4	-0.3	-0.9	-0.9	-0.7	-0.9	-0.4
Medication: Blood pressure	0.8	1.5	4.9	1.8	-0.3	-1.4	0.1	1.9	0.5	-0.8	-0.3	-1.4	-1.7	-1.0	-0.9	-1.7	-0.3	-0.7	-1.6	-0.3	-0.3	-0.5	-1.4	-1.8	-2.2	-1.9	-1.0	-1.5	-0.2	-0.3	-0.8	-0.2	-2.0
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.5	-0.4	-0.5	0.1	0.7	-0.5	-0.7	-0.4	-0.5	-0.1	-0.4	-0.2	-0.2	0.1	-0.6	-0.5	-0.1	-0.5	-0.6	-0.5	0.3	0.1	0.0	0.1	-0.1	0.1	-0.5	-0.4	-0.3	-0.5	-0.3
Supplements: Fish oil (including cod liver oil)	2.4	3.1	6.7	2.2	-1.7	-1.8	1.4	2.6	1.9	-1.6	-1.3	-0.5	-1.4	-2.0	-1.8	-2.0	-1.2	-1.5	-2.5	-1.4	-1.3	-1.2	-2.4	-1.8	-2.0	-2.4	-2.0	-2.3	-1.2	-1.4	-1.7	-1.2	-1.1
High cholesterol (Self-reported)	0.4	0.7	1.8	-0.5	1.1	0.6	-0.5	0.2	0.1	1.0	1.1	-0.1	0.2	0.9	0.8	-1.1	1.1	0.9	0.5	1.2	1.3	0.9	0.2	-0.9	-0.7	0.7	0.8	0.4	1.1	1.1	0.9	1.1	-0.1
Medication: Bendroflumethiazide	1.4	2.2	4.5	1.9	-1.0	-1.8	0.5	0.3	0.4	-1.5	-1.1	-2.0	-1.9	-1.6	-1.5	-1.4	-1.0	-1.3	-1.8	-1.1	-1.1	-1.3	-1.3	-1.9	-2.1	-1.8	-1.7	-1.9	-1.1	-1.1	-1.5	-1.1	-1.9
Medication: Paracetamol	0.3	0.4	1.5	0.7	-0.1	-0.8	0.1	0.6	0.9	-0.6	-0.7	-0.8	-1.1	-0.6	-0.7	-0.7	-0.6	-0.6	-0.7	-0.4	-0.5	-0.7	-0.9	-0.6	-0.3	-0.7	-0.6	-0.3	-0.5	-0.4	-0.6	-0.5	-1.2
Medication: Lisinopril	4.1	5.3	11.2	1.7	-1.5	-1.8	2.8	1.8	3.4	-2.6	-2.9	-2.9	-2.1	-2.1	-2.4	-2.1	-3.1	-2.4	-1.6	-2.2	-2.7	-3.0	-2.1	-1.6	-1.4	-1.2	-2.0	-2.2	-2.5	-2.4	-2.2	-2.5	-2.0
Medication: Atorvastatin	1.0	1.2	2.3	-0.6	1.4	0.8	-0.0	-0.1	-0.2	1.3	1.4	0.4	0.7	1.5	1.3	0.5	1.3	1.3	1.3	1.5	1.3	1.2	0.9	0.6	0.5	1.3	1.2	0.6	1.5	1.5	1.4	1.4	0.6
Illnesses of father: High blood pressure	0.3	0.3	1.1	0.8	-0.3	-0.6	0.2	0.7	0.0	-0.5	-0.5	-1.0	-0.6	-0.6	-0.6	-0.8	0.1	-0.5	-0.9	-0.4	-0.3	-0.6	-0.5	-1.1	-0.8	0.4	-0.3	-0.3	-0.4	-0.3	-0.5	-0.3	-0.8
Alcohol drinker status: Never	2.8	3.4	9.1	-2.6	1.5	2.3	-0.7	-1.7	-1.9	1.3	0.6	1.1	2.2	1.9	1.6	2.6	0.7	1.2	2.6	0.8	0.7	0.7	2.7	2.9	3.0	2.4	2.0	2.1	0.5	0.8	1.6	0.6	2.5
Ever smoked	0.8	1.4	3.3	-1.1	1.4	1.1	-1.6	-1.2	-1.3	1.4	1.5	0.6	1.0	1.3	1.3	0.6	1.8	1.4	1.2	1.3	1.6	1.3	1.1	0.2	0.4	-0.0	1.2	1.0	1.3	1.3	1.4	1.3	0.8
Basal metabolic rate	0.3	1.8	9.9	-2.4	-0.1	1.8	-1.0	-3.1	-1.3	0.6	0.1	0.8	2.0	1.2	1.1	1.0	0.2	0.4	1.8	-0.2	-0.0	0.2	1.4	1.8	1.9	-0.1	1.5	1.9	-0.0	0.1	0.9	-0.1	2.2
Leg fat percentage (left)	0.6	2.1	9.4	-2.2	1.3	2.1	-1.8	-3.1	-1.9	1.2	0.8	0.4	1.6	1.5	1.4	0.7	0.8	1.2	1.6	1.1	0.9	0.7	1.6	0.8	1.1	-0.2	1.8	1.9	1.0	1.1	1.4	1.0	1.7
Arm fat-free mass (left)	0.3	1.3	8.8	-2.1	-0.2	1.6	-0.6	-3.0	-0.8	0.2	-0.3	0.1	1.8	0.9	0.7	0.8	-0.2	0.0	1.6	-0.5	-0.3	-0.3	1.2	1.4	1.7	-0.1	1.3	1.4	-0.5	-0.3	0.5	-0.5	2.0
Number of operations (self-reported)	0.2	0.4	1.5	0.4	-0.4	-0.3	1.0	1.0	0.7	-0.6	-0.6	0.1	-1.0	-0.5	-0.7	0.4	-0.7	-0.5	-0.2	-0.6	-0.7	-0.6	-0.2	0.1	0.5	0.3	-0.5	-0.1	-0.7	-0.6	-0.6	-0.7	-1.2
Average weekly beer plus cider intake	0.3	0.4	1.6	0.2	-1.0	-0.4	1.0	0.3	1.0	-0.5	-0.4	-0.9	0.1	-0.5	-0.7	-1.1	-0.4	-0.7	-0.6	-0.5	-0.4	-0.6	-0.5	-0.9	-1.2	-0.8	-0.6	-0.6	-0.4	-0.4	-0.4	-0.4	0.4
Irritability	1.5	2.6	4.9	-0.5	1.9	0.8	-1.7	-0.6	-1.6	1.9	2.2	2.1	1.1	1.4	1.6	1.1	2.0	1.9	1.1	2.0	2.1	2.2	1.2	1.2	0.5	1.7	1.3	0.7	2.1	2.0	1.5	2.2	0.9
Risk taking	0.4	0.5	3.5	-0.6	0.4	0.7	-1.8	-0.8	-0.8	0.4	0.2	1.0	1.5	0.5	0.5	-0.4	0.0	0.1	0.5	0.2	0.2	0.3	0.4	1.0	-0.0	-0.4	0.6	0.4	0.2	0.3	0.5	0.3	1.9
Ever had prostate specific antigen (PSA) test	1.1	1.2	2.7	1.2	-1.4	-1.2	1.7	1.0	0.8	-1.1	-1.0	-0.9	-1.4	-1.2	-1.3	-0.1	-1.1	-1.0	-1.2	-1.0	-1.0	-1.0	-0.9	-1.2	-0.7	-0.4	-1.3	-1.4	-1.0	-1.1	-1.2	-1.0	-1.2
Fractured/broken bones in last 5 years	1.0	1.3	3.7	-1.2	1.0	1.5	-0.4	0.3	-0.7	1.2	1.0	0.9	1.3	1.4	1.2	0.8	1.1	1.2	1.2	0.9	1.1	1.0	1.1	1.1	0.8	1.9	1.3	1.4	1.1	1.1	1.3	1.0	1.2
Age started oral contraceptive pill	0.4	0.5	2.2	1.4	-0.6	-1.0	-0.0	0.8	-0.1	-0.2	0.2	0.4	-1.0	-0.6	-0.4	-0.3	0.4	-0.1	-1.0	0.1	0.2	0.2	-0.8	-1.3	-0.9	-1.5	-0.7	-0.9	0.2	0.2	-0.4	0.3	-1.2
Diastolic blood pressure, automated reading	3.3	10.4	14.5	3.7	-3.8	-3.7	2.2	1.9	3.6	-3.2	-2.7	-2.3	-3.3	-3.5	-3.6	-3.0	-2.8	-3.2	-3.7	-3.1	-2.8	-2.8	-3.7	-3.1	-3.5	-3.5	-3.8	-3.6	-2.8	-3.0	-3.4	-2.8	-3.2
Ever depressed for a whole week	1.3	1.6	3.3	-1.3	1.8	1.2	-1.0	-1.4	-0.4	1.3	1.2	-0.1	1.2	1.4	1.5	0.8	1.3	1.3	1.4	1.6	1.4	1.1	0.5	0.8	1.6	0.2	1.8	1.7	1.2	1.3	1.5	1.3	1.0
Unable to work because of sickness or disability	3.2	4.1	6.1	-2.0	2.2	1.9	-2.2	-1.7	-1.8	2.1	1.9	2.4	1.9	2.1	2.2	1.5	1.9	2.2	1.9	2.2	2.0	1.9	1.6	1.8	1.9	1.8	2.0	2.5	2.1	2.2	2.1	2.1	1.9
Commuting to job workplace: Cycle	0.1	0.1	1.2	0.5	0.1	-0.5	0.5	1.1	0.8	-0.0	0.1	-0.4	-0.1	-0.0	-0.3	0.3	0.3	0.1	-0.2	0.3	0.2	0.1	-0.3	-0.3	-0.0	-0.3	-0.3	-0.9	0.2	0.1	0.0	0.2	0.0
Myopia	0.6	0.8	2.0	1.0	-0.6	-1.1	0.7	1.2	0.9	-0.7	-0.7	-0.4	-1.0	-0.9	-0.9	-1.1	-0.6	-0.8	-1.0	-0.8	-0.7	-0.7	-0.9	-0.7	-1.3	-1.4	-1.2	-0.8	-0.7	-0.8	-0.9	-0.7	-0.7
Vascular/heart problems diagnosed by doctor	0.7	1.9	8.3	-1.9	-0.1	1.5	0.2	-1.3	-0.7	0.3	-0.2	1.3	1.7	0.8	0.6	2.5	-0.3	0.3	1.6	-0.4	-0.3	0.1	1.7	2.6	2.9	2.6	1.0	1.6	-0.4	-0.3	0.5	-0.5	2.0
Cholesterol lowering medication	0.7	1.0	2.7	-0.3	1.0	0.6	-0.7	-0.1	-0.3	1.4	1.6	1.2	0.5	1.0	1.1	-0.4	1.3	1.1	0.5	1.4	1.6	1.5	0.4	0.1	-0.3	0.5	0.9	0.4	1.4	1.4	1.0	1.4	0.2
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.8	-0.5	-0.6	0.2	1.4	-0.9	0.3	-0.6	-0.8	-1.3	-0.1	-0.2	-0.3	0.3	-0.8	-0.4	0.1	-0.7	-0.7	-1.0	0.1	-0.2	0.6	-0.5	-0.2	-0.4	-0.8	-0.7	-0.4	-0.8	0.0
Pain experienced in last month	2.4	4.0	5.7	2.0	-1.9	-2.1	2.3	0.7	2.3	-2.3	-2.3	-2.0	-1.9	-2.2	-2.3	-0.8	-2.3	-2.1	-1.8	-2.1	-2.4	-2.3	-1.8	-1.2	-0.9	-1.5	-2.2	-2.1	-2.3	-2.2	-2.3	-2.3	-1.6
Supplements: Calcium	3.0	3.3	6.3	-1.4	2.3	1.4	-2.5	-1.2	-1.3	2.1	2.2	1.9	1.4	1.8	1.9	1.4	2.4	2.2	1.5	2.1	2.3	2.1	1.1	1.4	1.5	1.5	1.8	1.6	2.1	2.0	1.9	2.1	0.9
Basal cell carcinoma (self-reported)	0.6	0.8	1.8	1.2	-1.0	-1.1	0.5	0.4	0.5	-0.8	-0.6	-0.4	-1.2	-0.8	-0.8	-1.2	-0.5	-0.9	-1.1	-0.5	-0.7	-0.6	-0.9	-1.1	-1.4	-1.3	-1.0	-1.1	-0.5	-0.5	-0.7	-0.4	-0.9
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.7	-0.3	0.4	0.0	-0.5	-0.6	-0.1	0.0	0.1	-0.2	0.3	0.0	0.0	0.8	0.1	0.3	0.1	0.1	0.2	-0.0	0.1	0.8	0.6	-0.0	0.1	-0.2	0.1	0.0	0.1	0.1	0.3
Deep venous thrombosis (DVT) (self-reported)	3.1	3.9	6.7	-2.4	2.4	2.3	-1.8	-1.9	-1.6	1.9	1.7	1.0	2.4	2.2	2.1	1.5	1.8	2.0	2.2	2.3	1.8	1.6	1.7	1.4	1.9	0.4	2.4	2.3	1.9	2.0	2.3	2.0	2.6
Heart disease (siblings)	0.2	0.3	1.9	-0.5	0.5	0.4	-0.5	-1.4	-0.8	0.3	0.1	0.1	0.4	0.4	0.3	1.0	0.1	0.4	0.5	0.2	0.1	0.0	0.9	0.5	1.0	0.1	0.4	0.7	0.0	0.1	0.2	0.0	0.5
Alcohol drinker status: Previous	4.3	4.9	8.2	-1.8	1.9	1.8	-2.1	-1.4	-2.0	2.7	2.9	2.5	1.4	2.3	2.6	0.8	2.9	2.4	1.9	2.7	2.8	2.8	1.5	0.9	0.8	0.8	2.1	2.8	2.8	2.9	2.6	2.9	1.2
Pack years of smoking	1.9	2.8	5.7	-1.7	1.8	1.8	-1.2	-1.6	-2.4	1.7	1.5	1.7	1.7	1.6	1.9	1.6	1.2	1.6	1.7	1.6	1.6	1.6	1.9	2.0	1.6	2.1	1.7	1.7	1.4	1.4	1.5	1.4	1.8
Impedance of whole body	0.7	3.7	11.8	3.4	-0.9	-2.8	0.9	3.1	1.7	-1.2	-0.7	-0.7	-2.7	-1.9	-2.0	-1.9	-0.5	-1.2	-2.7	-0.6	-0.7	-0.7	-2.1	-2.6	-3.0	-1.3	-2.5	-2.4	-0.6	-0.7	-1.6	-0.6	-2.7
Leg fat mass (left)	0.7	2.9	12.8	-2.6	1.2	2.4	-1.9	-3.6	-2.1	1.3	0.8	0.7	2.1	1.8	1.7	0.9	0.9	1.2	2.0	1.0	0.9	0.8	1.9	1.4	1.6	-0.1	2.1	2.4	0.9	1.0	1.6	0.9	2.3
Arm predicted mass (left)	0.3	1.4	8.0	-2.2	-0.2	1.7	-0.7	-2.8	-1.0	0.3	-0.2	0.2	1.8	0.9	0.8	0.8	-0.1	0.1	1.6	-0.4	-0.3	-0.2	1.2	1.5	1.8	-0.2	1.3	1.4	-0.4	-0.3	0.6	-0.4	2.0