[Hub]/) : Traits : Sitting height :

chr16:66,514,962-71,093,625

Best TWAS P=8.46e-24 · Best GWAS P=7.07e-37 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CDH3 0.07 0.04 blup 326 0.04 1.7e-05 1.11 5.1 3.0e-07 0.01 0.38 0.33 TRUE
2 CommonMind Brain Pre-frontal Cortex COG4 0.19 0.23 enet 28 0.27 4.3e-33 -4.90 5.6 2.1e-08 -0.25 0.93 0.07 FALSE
3 CommonMind Brain Pre-frontal Cortex COG8 0.09 0.13 lasso 5 0.14 6.9e-17 -6.99 -6.9 4.5e-12 0.09 1.00 0.00 TRUE
4 CommonMind Brain Pre-frontal Cortex NIP7 0.04 0.04 lasso 3 0.05 8.2e-07 -6.99 5.7 1.5e-08 -0.06 0.48 0.02 FALSE
5 CommonMind Brain Pre-frontal Cortex NOB1 0.04 0.05 enet 12 0.04 7.2e-06 -4.32 5.9 3.7e-09 -0.43 0.97 0.00 FALSE
6 CommonMind Brain Pre-frontal Cortex PDF 0.05 0.06 lasso 2 0.05 1.4e-06 -6.99 7.0 1.8e-12 -0.09 0.99 0.00 FALSE
7 CommonMind Brain Pre-frontal Cortex TPPP3 0.04 0.03 blup 222 0.03 2.0e-04 -5.37 7.7 1.6e-14 -0.01 0.14 0.66 TRUE
8 CommonMind Brain Pre-frontal Cortex VPS4A 0.07 0.12 enet 8 0.13 2.3e-15 -6.31 -6.9 7.0e-12 0.08 1.00 0.00 FALSE
9 GTEx Adipose Subcutaneous NFAT5 0.09 0.02 enet 19 0.05 8.2e-05 1.14 -6.6 3.8e-11 0.38 0.17 0.20 TRUE
10 GTEx Adipose Visceral Omentum NIP7 0.06 0.04 lasso 2 0.03 1.3e-02 -6.88 6.9 5.3e-12 -0.09 0.28 0.04 FALSE
11 GTEx Adipose Visceral Omentum TERF2 0.09 0.03 lasso 4 0.04 3.7e-03 -7.17 6.7 1.8e-11 -0.06 0.33 0.03 FALSE
12 GTEx Artery Aorta COG8 0.08 0.00 lasso 4 0.01 9.9e-02 -5.25 7.3 2.9e-13 -0.11 0.46 0.02 FALSE
13 GTEx Artery Aorta PDF 0.07 0.09 enet 11 0.09 9.4e-06 -6.99 7.6 3.7e-14 -0.07 0.94 0.00 FALSE
14 GTEx Artery Tibial PDF 0.09 0.08 lasso 4 0.09 2.0e-07 -6.99 6.9 5.3e-12 -0.10 1.00 0.00 FALSE
15 GTEx Brain Cerebellar Hemisphere KIAA0895L 0.36 0.14 lasso 9 0.14 2.5e-04 -4.96 -5.1 3.0e-07 -0.01 0.28 0.27 FALSE
16 GTEx Brain Cerebellum KIAA0895L 0.47 0.06 enet 39 0.13 1.5e-04 -4.87 -7.1 1.1e-12 -0.04 0.15 0.62 FALSE
17 GTEx Brain Cerebellum RP11-296I10.3 0.20 0.03 enet 12 0.14 8.8e-05 -0.66 5.5 3.1e-08 -0.36 0.04 0.26 FALSE
18 GTEx Brain Cortex LRRC29 0.53 0.02 enet 20 0.12 3.2e-04 -6.38 -5.3 1.2e-07 -0.03 0.03 0.67 FALSE
19 GTEx Breast Mammary Tissue SNTB2 0.14 0.07 lasso 5 0.07 2.3e-04 -6.59 6.9 5.5e-12 -0.12 0.80 0.01 FALSE
20 GTEx Breast Mammary Tissue PDF 0.08 0.05 lasso 3 0.03 7.3e-03 -6.42 6.8 1.0e-11 -0.13 0.26 0.04 TRUE
21 GTEx Breast Mammary Tissue (Male) SNTB2 0.18 0.08 lasso 3 0.05 2.8e-02 -5.34 6.2 7.4e-10 -0.05 0.12 0.05 FALSE
22 GTEx Breast Mammary Tissue (Male) PDF 0.11 0.03 lasso 5 0.04 4.9e-02 -6.88 7.0 3.7e-12 -0.09 0.04 0.09 FALSE
23 GTEx Breast Mammary Tissue (Female) PDF 0.07 -0.01 lasso 2 0.00 3.0e-01 3.35 6.6 4.5e-11 -0.31 0.03 0.16 FALSE
24 GTEx Cells Transformed fibroblasts COG4 0.23 0.18 lasso 5 0.20 1.3e-14 -4.79 5.7 1.6e-08 -0.24 0.94 0.05 FALSE
25 GTEx Cells Transformed fibroblasts NIP7 0.06 0.06 lasso 2 0.06 5.3e-05 -6.31 6.5 6.3e-11 -0.08 0.76 0.01 FALSE
26 GTEx Cells Transformed fibroblasts PDF 0.05 0.06 lasso 1 0.05 2.5e-04 -6.99 7.0 2.7e-12 -0.09 0.57 0.02 FALSE
27 GTEx Colon Transverse TMED6 0.22 0.23 lasso 2 0.21 1.9e-10 5.79 -6.0 2.1e-09 0.14 1.00 0.00 FALSE
28 GTEx Colon Transverse PDF 0.20 0.05 enet 27 0.16 5.0e-08 -6.59 5.3 1.5e-07 -0.08 0.70 0.02 FALSE
29 GTEx Esophagus Mucosa COG4 0.14 0.06 lasso 4 0.08 7.8e-06 -4.90 5.1 2.7e-07 -0.22 0.83 0.07 FALSE
30 GTEx Esophagus Mucosa TERF2 0.05 0.05 lasso 3 0.05 5.3e-04 -6.92 6.9 4.4e-12 -0.12 0.32 0.03 FALSE
31 GTEx Esophagus Mucosa SNTB2 0.09 0.06 lasso 2 0.04 1.0e-03 -5.34 5.4 6.6e-08 -0.04 0.54 0.03 FALSE
32 GTEx Esophagus Mucosa PDF 0.05 0.01 lasso 3 0.01 1.3e-01 -6.62 6.8 1.1e-11 -0.10 0.32 0.03 FALSE
33 GTEx Esophagus Muscularis TMED6 0.08 0.04 enet 5 0.06 1.2e-04 -7.71 -8.0 1.4e-15 0.11 0.33 0.03 TRUE
34 GTEx Esophagus Muscularis COG8 0.06 0.05 lasso 3 0.04 2.1e-03 -6.88 6.9 4.8e-12 -0.08 0.46 0.02 FALSE
35 GTEx Esophagus Muscularis PDF 0.08 0.08 lasso 3 0.05 4.0e-04 -7.71 7.7 1.9e-14 -0.09 0.81 0.01 FALSE
36 GTEx Liver TMED6 0.37 0.22 lasso 7 0.24 1.9e-07 4.38 -6.8 7.3e-12 0.15 0.61 0.03 FALSE
37 GTEx Lung SNTB2 0.08 0.05 enet 12 0.04 2.8e-04 -6.42 7.8 4.1e-15 -0.25 0.60 0.15 TRUE
38 GTEx Lung PDF 0.04 0.02 enet 17 0.04 7.9e-04 -6.88 5.9 3.1e-09 -0.08 0.19 0.03 FALSE
39 GTEx Muscle Skeletal TANGO6 0.05 0.01 lasso 4 0.00 2.6e-01 -7.02 -7.7 1.6e-14 0.09 0.32 0.04 FALSE
40 GTEx Nerve Tibial PDF 0.07 0.03 lasso 2 0.02 2.2e-02 -6.38 6.4 1.7e-10 -0.13 0.30 0.11 FALSE
41 GTEx Ovary EXOSC6 0.32 -0.01 enet 34 0.09 2.7e-03 4.07 5.1 2.9e-07 -0.50 0.06 0.25 FALSE
42 GTEx Pancreas TMED6 0.73 0.64 lasso 11 0.63 1.9e-33 5.79 -5.8 4.9e-09 0.14 1.00 0.00 FALSE
43 GTEx Pancreas TPPP3 0.24 0.01 lasso 4 0.00 2.0e-01 -6.44 -6.5 9.2e-11 -0.03 0.01 0.83 FALSE
44 GTEx Skin Not Sun Exposed Suprapubic PDF 0.09 0.02 lasso 3 0.01 1.2e-01 -6.49 7.2 7.3e-13 -0.15 0.19 0.28 FALSE
45 GTEx Skin Sun Exposed Lower leg CYB5B 0.12 0.00 enet 18 0.02 5.4e-03 -0.18 -6.5 6.8e-11 0.48 0.32 0.40 FALSE
46 GTEx Skin Sun Exposed Lower leg SNTB2 0.10 0.09 lasso 6 0.07 9.7e-07 -6.42 6.2 4.8e-10 -0.06 0.99 0.00 FALSE
47 GTEx Skin Sun Exposed Lower leg PDF 0.05 0.05 enet 5 0.05 4.2e-05 -6.59 6.8 1.3e-11 -0.12 0.62 0.01 FALSE
48 GTEx Spleen TMED6 0.17 0.00 lasso 7 0.07 8.7e-03 -6.92 -5.4 8.2e-08 0.06 0.09 0.05 FALSE
49 GTEx Stomach TMED6 0.54 0.42 lasso 5 0.41 4.7e-21 5.79 -5.9 3.3e-09 0.16 1.00 0.00 FALSE
50 GTEx Testis TMED6 0.19 0.08 lasso 4 0.05 4.2e-03 4.55 -5.3 1.2e-07 0.16 0.32 0.04 FALSE
51 GTEx Testis WWP2 0.30 0.10 lasso 5 0.16 9.2e-08 -5.94 -9.1 8.6e-20 0.68 0.51 0.25 TRUE
52 GTEx Thyroid NIP7 0.11 0.12 lasso 4 0.13 2.9e-10 -6.88 7.2 7.0e-13 -0.10 1.00 0.00 FALSE
53 GTEx Thyroid TERF2 0.12 0.12 lasso 5 0.14 1.6e-10 -6.89 7.1 1.6e-12 -0.10 1.00 0.00 FALSE
54 GTEx Thyroid GFOD2 0.18 0.01 enet 16 0.02 1.1e-02 -0.72 -5.2 1.5e-07 -0.02 0.03 0.63 FALSE
55 GTEx Thyroid NOB1 0.03 0.01 enet 6 0.02 7.7e-03 -6.97 7.4 1.6e-13 -0.76 0.26 0.18 FALSE
56 GTEx Thyroid SNTB2 0.12 0.15 lasso 6 0.16 1.8e-12 -7.65 7.5 7.5e-14 -0.09 1.00 0.00 FALSE
57 GTEx Thyroid CTD-2033A16.3 0.03 0.02 enet 7 0.02 6.7e-03 -6.63 7.6 3.0e-14 -0.72 0.21 0.27 FALSE
58 METSIM Adipose NOB1 0.03 0.03 lasso 2 0.03 2.8e-05 -3.86 5.2 1.8e-07 -0.57 0.28 0.67 FALSE
59 YFS Blood SNTB2 0.10 0.09 blup 354 0.11 6.9e-34 -5.76 -5.3 1.4e-07 0.10 1.00 0.00 FALSE
60 YFS Blood TERF2 0.02 0.02 lasso 7 0.02 1.5e-07 -6.38 6.5 7.4e-11 -0.12 1.00 0.00 FALSE
61 The Cancer Genome Atlas Bladder Urothelial Carcinoma PDF 0.03 0.02 blup 37 0.03 1.5e-03 -6.59 6.5 6.0e-11 -0.08 0.03 0.88 FALSE
62 The Cancer Genome Atlas Bladder Urothelial Carcinoma TMED6 0.07 0.01 enet 4 0.04 3.7e-04 -6.49 -6.2 4.8e-10 0.08 0.02 0.89 FALSE
63 The Cancer Genome Atlas Breast Invasive Carcinoma KCTD19 0.02 0.02 blup 29 0.03 3.5e-06 -5.93 -6.1 8.3e-10 0.01 0.08 0.91 FALSE
64 The Cancer Genome Atlas Breast Invasive Carcinoma LRRC36 0.04 0.04 enet 8 0.05 5.8e-10 -5.93 -6.0 2.6e-09 0.03 0.10 0.90 FALSE
65 The Cancer Genome Atlas Breast Invasive Carcinoma NFAT5 0.02 0.01 enet 5 0.01 6.6e-04 -4.38 -9.2 2.1e-20 0.76 0.04 0.07 TRUE
66 The Cancer Genome Atlas Breast Invasive Carcinoma NIP7 0.01 0.01 lasso 3 0.01 2.2e-03 -7.17 7.0 3.0e-12 -0.09 0.01 0.96 FALSE
67 The Cancer Genome Atlas Breast Invasive Carcinoma NQO1 0.02 0.01 blup 39 0.01 4.3e-03 -7.04 -10.1 8.5e-24 0.73 0.04 0.51 TRUE
68 The Cancer Genome Atlas Breast Invasive Carcinoma PDF 0.05 0.03 enet 10 0.04 2.4e-08 -6.91 5.5 4.0e-08 -0.06 0.01 0.99 FALSE
69 The Cancer Genome Atlas Breast Invasive Carcinoma SLC9A5 0.01 0.00 blup 30 0.01 1.1e-02 -5.16 -5.1 2.8e-07 -0.05 0.02 0.45 FALSE
70 The Cancer Genome Atlas Breast Invasive Carcinoma SNTB2 0.02 0.02 lasso 3 0.01 1.0e-03 -6.44 6.0 1.6e-09 -0.06 0.11 0.78 FALSE
71 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PDXDC2 0.20 0.02 blup 26 0.07 1.8e-04 4.07 6.0 2.0e-09 -0.35 0.06 0.34 FALSE
72 The Cancer Genome Atlas Colon Adenocarcinoma NQO1 0.06 0.04 lasso 3 0.01 5.3e-02 -7.04 -7.0 3.7e-12 0.53 0.03 0.32 FALSE
73 The Cancer Genome Atlas Colon Adenocarcinoma PDF 0.07 0.09 blup 36 0.09 9.9e-06 -6.99 7.0 1.8e-12 -0.11 0.03 0.97 FALSE
74 The Cancer Genome Atlas Colon Adenocarcinoma TERF2 0.05 0.03 blup 46 0.02 1.9e-02 -6.42 5.4 6.9e-08 -0.09 0.02 0.68 FALSE
75 The Cancer Genome Atlas Colon Adenocarcinoma TMED6 0.37 0.29 lasso 4 0.28 3.1e-16 5.79 -6.2 7.2e-10 0.15 0.95 0.05 FALSE
76 The Cancer Genome Atlas Esophageal Carcinoma PDF 0.12 0.00 blup 37 0.05 1.2e-02 -6.88 6.6 4.2e-11 -0.10 0.01 0.78 FALSE
77 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PDF 0.06 0.06 enet 13 0.06 1.6e-07 -6.91 7.3 2.8e-13 -0.15 0.02 0.98 FALSE
78 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NIP7 0.02 0.02 lasso 2 0.01 2.4e-02 -6.59 6.9 6.4e-12 -0.12 0.02 0.74 FALSE
79 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDF 0.04 0.05 blup 37 0.06 3.6e-07 -6.59 7.3 2.8e-13 -0.12 0.02 0.98 FALSE
80 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TMED6 0.47 0.31 lasso 3 0.37 3.6e-43 5.79 -6.0 2.3e-09 0.15 0.95 0.05 FALSE
81 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma NIP7 0.06 0.05 enet 6 0.04 3.4e-03 -6.33 6.6 4.1e-11 -0.12 0.04 0.42 FALSE
82 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma TMED6 0.31 0.19 lasso 4 0.20 1.5e-11 5.79 -5.8 5.3e-09 0.15 0.95 0.05 FALSE
83 The Cancer Genome Atlas Brain Lower Grade Glioma NIP7 0.05 0.05 blup 39 0.04 9.2e-06 -7.17 5.2 1.9e-07 -0.03 0.00 0.99 FALSE
84 The Cancer Genome Atlas Brain Lower Grade Glioma PDF 0.07 0.07 blup 37 0.08 2.8e-09 -7.17 6.5 7.3e-11 -0.09 0.00 1.00 FALSE
85 The Cancer Genome Atlas Brain Lower Grade Glioma TERF2 0.02 0.03 lasso 4 0.03 6.6e-04 -6.92 7.0 1.9e-12 -0.12 0.02 0.92 FALSE
86 The Cancer Genome Atlas Liver Hepatocellular Carcinoma TMED6 0.21 0.06 enet 11 0.14 2.5e-07 4.38 -6.3 3.3e-10 0.16 0.07 0.83 FALSE
87 The Cancer Genome Atlas Lung Adenocarcinoma COG4 0.03 0.00 blup 30 0.01 9.7e-03 -4.82 5.2 1.7e-07 -0.19 0.02 0.73 FALSE
88 The Cancer Genome Atlas Lung Adenocarcinoma PDF 0.03 0.02 enet 6 0.03 7.5e-05 -6.99 7.2 4.1e-13 -0.11 0.01 0.99 FALSE
89 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PDF 0.06 0.07 lasso 5 0.07 3.5e-08 -6.88 7.0 2.3e-12 -0.10 0.01 0.99 FALSE
90 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PDF 0.03 0.01 blup 37 0.02 2.1e-02 -6.31 6.8 9.8e-12 -0.09 0.02 0.66 FALSE
91 The Cancer Genome Atlas Pancreatic Adenocarcinoma PDF 0.10 0.13 blup 37 0.12 1.1e-05 -6.88 6.6 5.1e-11 -0.07 0.01 0.98 FALSE
92 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma COG4 0.11 0.04 lasso 3 0.06 2.3e-03 -4.79 5.5 3.4e-08 -0.23 0.02 0.92 FALSE
93 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PDF 0.14 0.09 lasso 2 0.08 6.4e-04 -6.99 6.9 5.5e-12 -0.09 0.01 0.94 FALSE
94 The Cancer Genome Atlas Prostate Adenocarcinoma FHOD1 0.08 0.08 lasso 10 0.09 2.4e-09 -5.16 -5.1 2.8e-07 -0.02 0.85 0.15 TRUE
95 The Cancer Genome Atlas Prostate Adenocarcinoma NIP7 0.03 0.03 lasso 2 0.03 8.9e-04 -6.99 6.9 4.7e-12 -0.11 0.02 0.92 FALSE
96 The Cancer Genome Atlas Prostate Adenocarcinoma NQO1 0.10 0.00 enet 21 0.02 6.8e-03 7.24 -5.2 2.5e-07 0.19 0.01 0.16 FALSE
97 The Cancer Genome Atlas Prostate Adenocarcinoma PDF 0.09 0.18 enet 11 0.20 2.3e-20 -6.88 7.1 1.2e-12 -0.11 0.02 0.98 FALSE
98 The Cancer Genome Atlas Prostate Adenocarcinoma TERF2 0.04 0.04 blup 47 0.03 2.6e-04 -6.41 7.0 2.3e-12 -0.10 0.06 0.92 FALSE
99 The Cancer Genome Atlas Rectum Adenocarcinoma PDF 0.14 0.07 blup 37 0.07 1.2e-02 -6.36 6.8 7.4e-12 -0.08 0.02 0.68 FALSE
100 The Cancer Genome Atlas Rectum Adenocarcinoma TMED6 0.55 0.07 enet 20 0.13 6.4e-04 5.79 -6.0 1.6e-09 0.12 0.01 0.44 FALSE
101 The Cancer Genome Atlas Soft Tissue Sarcoma PDF 0.13 0.09 blup 37 0.09 3.6e-06 -6.91 5.7 1.1e-08 -0.07 0.01 0.99 FALSE
102 The Cancer Genome Atlas Skin Cutaneous Melanoma COG4 0.26 -0.01 blup 30 0.02 1.1e-01 -3.26 6.9 6.9e-12 -0.27 0.01 0.48 FALSE
103 The Cancer Genome Atlas Stomach Adenocarcinoma PDF 0.04 0.04 blup 37 0.03 2.6e-03 -6.91 7.4 1.3e-13 -0.13 0.02 0.95 FALSE
104 The Cancer Genome Atlas Stomach Adenocarcinoma TMED6 0.18 0.14 enet 11 0.15 3.2e-11 5.79 -5.9 3.9e-09 0.13 0.66 0.34 FALSE
105 The Cancer Genome Atlas Thyroid Carcinoma C16orf48 0.04 0.02 blup 17 0.04 8.5e-05 -1.91 5.2 2.3e-07 -0.08 0.00 0.06 FALSE
106 The Cancer Genome Atlas Thyroid Carcinoma COG4 0.30 0.11 enet 15 0.12 3.1e-11 -4.90 5.7 1.1e-08 -0.20 0.02 0.98 FALSE
107 The Cancer Genome Atlas Thyroid Carcinoma NIP7 0.11 0.18 lasso 4 0.18 5.7e-17 -6.91 6.7 2.6e-11 -0.09 0.01 0.99 FALSE
108 The Cancer Genome Atlas Thyroid Carcinoma PDF 0.05 0.04 blup 36 0.04 9.8e-05 -7.03 7.0 1.9e-12 -0.12 0.01 0.98 FALSE
109 The Cancer Genome Atlas Thyroid Carcinoma SNTB2 0.05 0.01 blup 41 0.04 6.9e-05 0.95 5.5 3.8e-08 -0.05 0.06 0.71 FALSE
110 The Cancer Genome Atlas Thyroid Carcinoma TERF2 0.04 0.05 lasso 1 0.04 9.2e-05 -6.38 6.4 1.8e-10 -0.13 0.11 0.85 FALSE