[Hub]/) : Traits : Impedance of whole body :

chr1:149,672,809-152,126,467

Best TWAS P=3.74e-30 · Best GWAS P=4.43e-41 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CTSS 0.04 0.01 bslmm 313 0.02 5.5e-04 3.7 -5.4 5.3e-08 0.13 0.43 0.12 TRUE
2 GTEx Adipose Subcutaneous MTMR11 0.08 0.04 lasso 4 0.05 3.5e-05 -8.1 -8.6 1.3e-17 -0.37 0.78 0.03 FALSE
3 GTEx Adipose Subcutaneous TARS2 0.06 0.02 enet 8 0.03 2.2e-03 -4.2 5.2 2.2e-07 -0.04 0.58 0.03 TRUE
4 GTEx Adrenal Gland CTSS 0.12 0.13 lasso 9 0.08 7.0e-04 -5.8 -5.6 2.5e-08 0.00 0.46 0.40 FALSE
5 GTEx Artery Aorta RPRD2 0.08 -0.01 enet 19 0.00 4.2e-01 -5.2 8.9 4.5e-19 0.30 0.08 0.26 TRUE
6 GTEx Artery Tibial ARNT 0.09 0.07 lasso 3 0.06 1.5e-05 5.0 -5.2 2.4e-07 -0.07 0.47 0.33 FALSE
7 GTEx Artery Tibial HIST2H2AA3 0.22 0.02 enet 20 0.12 1.8e-09 12.4 10.5 1.3e-25 0.70 0.00 1.00 TRUE
8 GTEx Artery Tibial RP11-196G18.22 0.25 0.05 lasso 5 0.07 1.8e-06 9.7 11.4 3.7e-30 0.78 0.01 0.98 TRUE
9 GTEx Artery Tibial RP11-196G18.24 0.31 0.08 enet 26 0.10 6.1e-08 12.4 9.2 2.7e-20 0.72 0.00 0.99 FALSE
10 GTEx Brain Cerebellar Hemisphere RP11-316M1.12 0.31 0.37 lasso 4 0.39 4.5e-11 -4.1 5.3 1.5e-07 0.01 0.98 0.02 FALSE
11 GTEx Brain Hippocampus ARNT 0.14 0.09 enet 14 0.08 5.3e-03 -3.9 -5.9 3.2e-09 0.00 0.09 0.18 FALSE
12 GTEx Breast Mammary Tissue (Male) RP11-54A4.2 0.07 0.01 enet 2 0.03 7.4e-02 5.3 5.4 5.6e-08 0.08 0.04 0.16 TRUE
13 GTEx Esophagus Muscularis BOLA1 0.07 0.00 lasso 4 0.00 2.5e-01 -7.7 9.6 5.5e-22 0.43 0.03 0.13 FALSE
14 GTEx Heart Left Ventricle MTMR11 0.11 0.05 lasso 3 0.05 9.3e-04 -7.7 -6.6 3.1e-11 -0.39 0.20 0.13 FALSE
15 GTEx Lung MTMR11 0.08 0.04 lasso 8 0.03 3.0e-03 -8.1 -7.9 2.4e-15 -0.29 0.19 0.11 FALSE
16 GTEx Muscle Skeletal CTSS 0.04 0.01 enet 13 0.03 1.4e-03 -5.6 -5.7 1.1e-08 -0.01 0.50 0.04 TRUE
17 GTEx Skin Sun Exposed Lower leg MTMR11 0.03 0.01 lasso 5 0.00 1.2e-01 -7.7 -5.5 4.5e-08 -0.39 0.05 0.05 FALSE
18 GTEx Skin Sun Exposed Lower leg GABPB2 0.12 0.01 enet 16 0.04 1.8e-04 6.2 -5.2 1.7e-07 -0.03 0.14 0.10 FALSE
19 GTEx Skin Sun Exposed Lower leg SV2A 0.07 0.00 enet 15 0.02 6.0e-03 -1.4 -5.3 1.4e-07 -0.16 0.07 0.12 FALSE
20 GTEx Spleen RP11-54A4.2 0.29 0.10 lasso 9 0.04 3.8e-02 -5.8 6.2 7.7e-10 0.04 0.26 0.20 FALSE
21 GTEx Stomach CTSS 0.05 0.02 enet 16 0.00 2.8e-01 -4.1 -5.6 2.8e-08 -0.01 0.06 0.78 FALSE
22 GTEx Testis CTSK 0.07 0.01 enet 19 0.01 1.2e-01 -4.0 -5.3 8.6e-08 -0.03 0.18 0.54 FALSE
23 GTEx Thyroid MTMR11 0.09 0.05 enet 9 0.06 1.5e-05 -7.7 -6.5 9.4e-11 -0.40 0.26 0.42 FALSE
24 GTEx Thyroid PRUNE 0.11 0.00 enet 21 0.03 3.1e-03 -1.6 -5.7 1.1e-08 -0.07 0.42 0.02 FALSE
25 GTEx Thyroid ANP32E 0.08 0.00 enet 15 0.01 8.6e-02 -7.1 9.3 1.2e-20 0.37 0.04 0.11 TRUE
26 GTEx Thyroid ARNT 0.08 0.10 lasso 10 0.10 7.8e-08 4.6 -5.6 2.8e-08 -0.05 0.88 0.12 TRUE
27 METSIM Adipose POGZ 0.06 0.05 lasso 12 0.03 9.3e-06 -4.9 -5.7 1.0e-08 -0.05 0.98 0.01 FALSE
28 METSIM Adipose RP11-196G18.24 0.27 0.01 blup 116 0.13 3.6e-19 1.9 6.4 1.3e-10 0.31 0.04 0.94 FALSE
29 METSIM Adipose SCNM1 0.06 0.06 lasso 10 0.05 3.6e-08 5.3 5.6 1.9e-08 0.14 0.90 0.09 FALSE
30 METSIM Adipose TMOD4 0.02 0.00 blup 312 0.01 3.2e-02 -6.8 7.2 7.0e-13 0.11 0.03 0.65 FALSE
31 YFS Blood MCL1 0.07 0.03 bslmm 278 0.03 4.4e-10 5.0 -6.5 8.3e-11 -0.10 0.86 0.14 FALSE
32 YFS Blood SCNM1 0.09 0.04 enet 62 0.08 1.3e-24 -4.6 6.4 1.7e-10 0.05 1.00 0.00 FALSE
33 The Cancer Genome Atlas Bladder Urothelial Carcinoma C1orf54 0.06 0.02 blup 17 0.03 2.5e-03 -5.4 5.1 2.7e-07 -0.10 0.02 0.19 FALSE
34 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C1orf54 0.04 0.04 lasso 2 0.03 2.0e-04 -5.4 5.3 1.4e-07 -0.10 0.12 0.58 FALSE
35 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C1orf54 0.06 0.03 lasso 1 0.03 1.3e-04 -5.4 5.4 6.6e-08 -0.10 0.04 0.22 FALSE
36 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PSMB4 0.03 0.00 blup 37 0.02 7.0e-03 -4.9 6.7 2.5e-11 0.13 0.01 0.76 TRUE
37 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SV2A 0.05 0.02 blup 9 0.03 2.5e-04 -7.7 7.1 1.2e-12 0.48 0.03 0.07 TRUE
38 The Cancer Genome Atlas Brain Lower Grade Glioma SV2A 0.04 0.00 blup 9 0.03 5.5e-04 -8.3 -8.4 4.0e-17 -0.21 0.00 0.33 TRUE
39 The Cancer Genome Atlas Lung Adenocarcinoma ADAMTSL4 0.02 0.00 blup 33 0.02 4.7e-03 1.6 -5.4 5.4e-08 0.04 0.02 0.37 FALSE
40 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MRPS21 0.04 0.03 blup 15 0.04 4.0e-05 3.0 -6.3 2.6e-10 0.02 0.08 0.18 FALSE
41 The Cancer Genome Atlas Prostate Adenocarcinoma ARNT 0.06 0.02 lasso 3 0.02 1.4e-03 5.0 -5.3 1.3e-07 -0.05 0.01 0.89 FALSE
42 The Cancer Genome Atlas Prostate Adenocarcinoma ENSA 0.02 0.01 enet 3 0.01 2.5e-02 -5.2 7.1 1.0e-12 0.08 0.00 0.78 FALSE
43 The Cancer Genome Atlas Prostate Adenocarcinoma MTMR11 0.02 0.02 lasso 3 0.02 3.7e-03 -8.1 -8.2 2.4e-16 -0.30 0.03 0.03 FALSE
44 The Cancer Genome Atlas Prostate Adenocarcinoma SF3B4 0.03 0.02 blup 10 0.01 1.4e-02 -8.1 -9.4 7.5e-21 -0.32 0.04 0.16 FALSE
45 The Cancer Genome Atlas Skin Cutaneous Melanoma FCGR1A 0.10 0.03 lasso 4 0.04 3.9e-02 -7.7 5.7 1.1e-08 0.38 0.01 0.06 FALSE
46 The Cancer Genome Atlas Thyroid Carcinoma SELENBP1 0.06 0.02 enet 7 0.05 2.3e-05 -4.9 -6.2 4.0e-10 -0.13 0.01 0.98 FALSE