[Hub]/) : Traits : Impedance of whole body : ← →

chr1:149,672,809-152,126,467

Best TWAS P=3.74e-30 · Best GWAS P=4.43e-41 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Artery Tibial	RP11-196G18.22	0.25	0.05	lasso	5	0.07	1.8e-06	9.7	11.4	3.7e-30	0.78	0.01	0.98	TRUE
7	GTEx	Artery Tibial	HIST2H2AA3	0.22	0.02	enet	20	0.12	1.8e-09	12.4	10.5	1.3e-25	0.70	0.00	1.00	TRUE
25	GTEx	Thyroid	ANP32E	0.08	0.00	enet	15	0.01	8.6e-02	-7.1	9.3	1.2e-20	0.37	0.04	0.11	TRUE
5	GTEx	Artery Aorta	RPRD2	0.08	-0.01	enet	19	0.00	4.2e-01	-5.2	8.9	4.5e-19	0.30	0.08	0.26	TRUE
38	The Cancer Genome Atlas	Brain Lower Grade Glioma	SV2A	0.04	0.00	blup	9	0.03	5.5e-04	-8.3	-8.4	4.0e-17	-0.21	0.00	0.33	TRUE
37	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SV2A	0.05	0.02	blup	9	0.03	2.5e-04	-7.7	7.1	1.2e-12	0.48	0.03	0.07	TRUE
36	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMB4	0.03	0.00	blup	37	0.02	7.0e-03	-4.9	6.7	2.5e-11	0.13	0.01	0.76	TRUE
16	GTEx	Muscle Skeletal	CTSS	0.04	0.01	enet	13	0.03	1.4e-03	-5.6	-5.7	1.1e-08	-0.01	0.50	0.04	TRUE
26	GTEx	Thyroid	ARNT	0.08	0.10	lasso	10	0.10	7.8e-08	4.6	-5.6	2.8e-08	-0.05	0.88	0.12	TRUE
1	CommonMind	Brain Pre-frontal Cortex	CTSS	0.04	0.01	bslmm	313	0.02	5.5e-04	3.7	-5.4	5.3e-08	0.13	0.43	0.12	TRUE
12	GTEx	Breast Mammary Tissue (Male)	RP11-54A4.2	0.07	0.01	enet	2	0.03	7.4e-02	5.3	5.4	5.6e-08	0.08	0.04	0.16	TRUE
3	GTEx	Adipose Subcutaneous	TARS2	0.06	0.02	enet	8	0.03	2.2e-03	-4.2	5.2	2.2e-07	-0.04	0.58	0.03	TRUE
13	GTEx	Esophagus Muscularis	BOLA1	0.07	0.00	lasso	4	0.00	2.5e-01	-7.7	9.6	5.5e-22	0.43	0.03	0.13	FALSE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	SF3B4	0.03	0.02	blup	10	0.01	1.4e-02	-8.1	-9.4	7.5e-21	-0.32	0.04	0.16	FALSE
9	GTEx	Artery Tibial	RP11-196G18.24	0.31	0.08	enet	26	0.10	6.1e-08	12.4	9.2	2.7e-20	0.72	0.00	0.99	FALSE
2	GTEx	Adipose Subcutaneous	MTMR11	0.08	0.04	lasso	4	0.05	3.5e-05	-8.1	-8.6	1.3e-17	-0.37	0.78	0.03	FALSE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	MTMR11	0.02	0.02	lasso	3	0.02	3.7e-03	-8.1	-8.2	2.4e-16	-0.30	0.03	0.03	FALSE
15	GTEx	Lung	MTMR11	0.08	0.04	lasso	8	0.03	3.0e-03	-8.1	-7.9	2.4e-15	-0.29	0.19	0.11	FALSE
30	METSIM	Adipose	TMOD4	0.02	0.00	blup	312	0.01	3.2e-02	-6.8	7.2	7.0e-13	0.11	0.03	0.65	FALSE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	ENSA	0.02	0.01	enet	3	0.01	2.5e-02	-5.2	7.1	1.0e-12	0.08	0.00	0.78	FALSE
14	GTEx	Heart Left Ventricle	MTMR11	0.11	0.05	lasso	3	0.05	9.3e-04	-7.7	-6.6	3.1e-11	-0.39	0.20	0.13	FALSE
31	YFS	Blood	MCL1	0.07	0.03	bslmm	278	0.03	4.4e-10	5.0	-6.5	8.3e-11	-0.10	0.86	0.14	FALSE
23	GTEx	Thyroid	MTMR11	0.09	0.05	enet	9	0.06	1.5e-05	-7.7	-6.5	9.4e-11	-0.40	0.26	0.42	FALSE
28	METSIM	Adipose	RP11-196G18.24	0.27	0.01	blup	116	0.13	3.6e-19	1.9	6.4	1.3e-10	0.31	0.04	0.94	FALSE
32	YFS	Blood	SCNM1	0.09	0.04	enet	62	0.08	1.3e-24	-4.6	6.4	1.7e-10	0.05	1.00	0.00	FALSE
40	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MRPS21	0.04	0.03	blup	15	0.04	4.0e-05	3.0	-6.3	2.6e-10	0.02	0.08	0.18	FALSE
46	The Cancer Genome Atlas	Thyroid Carcinoma	SELENBP1	0.06	0.02	enet	7	0.05	2.3e-05	-4.9	-6.2	4.0e-10	-0.13	0.01	0.98	FALSE
20	GTEx	Spleen	RP11-54A4.2	0.29	0.10	lasso	9	0.04	3.8e-02	-5.8	6.2	7.7e-10	0.04	0.26	0.20	FALSE
11	GTEx	Brain Hippocampus	ARNT	0.14	0.09	enet	14	0.08	5.3e-03	-3.9	-5.9	3.2e-09	0.00	0.09	0.18	FALSE
27	METSIM	Adipose	POGZ	0.06	0.05	lasso	12	0.03	9.3e-06	-4.9	-5.7	1.0e-08	-0.05	0.98	0.01	FALSE
24	GTEx	Thyroid	PRUNE	0.11	0.00	enet	21	0.03	3.1e-03	-1.6	-5.7	1.1e-08	-0.07	0.42	0.02	FALSE
45	The Cancer Genome Atlas	Skin Cutaneous Melanoma	FCGR1A	0.10	0.03	lasso	4	0.04	3.9e-02	-7.7	5.7	1.1e-08	0.38	0.01	0.06	FALSE
29	METSIM	Adipose	SCNM1	0.06	0.06	lasso	10	0.05	3.6e-08	5.3	5.6	1.9e-08	0.14	0.90	0.09	FALSE
4	GTEx	Adrenal Gland	CTSS	0.12	0.13	lasso	9	0.08	7.0e-04	-5.8	-5.6	2.5e-08	0.00	0.46	0.40	FALSE
21	GTEx	Stomach	CTSS	0.05	0.02	enet	16	0.00	2.8e-01	-4.1	-5.6	2.8e-08	-0.01	0.06	0.78	FALSE
17	GTEx	Skin Sun Exposed Lower leg	MTMR11	0.03	0.01	lasso	5	0.00	1.2e-01	-7.7	-5.5	4.5e-08	-0.39	0.05	0.05	FALSE
39	The Cancer Genome Atlas	Lung Adenocarcinoma	ADAMTSL4	0.02	0.00	blup	33	0.02	4.7e-03	1.6	-5.4	5.4e-08	0.04	0.02	0.37	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1orf54	0.06	0.03	lasso	1	0.03	1.3e-04	-5.4	5.4	6.6e-08	-0.10	0.04	0.22	FALSE
22	GTEx	Testis	CTSK	0.07	0.01	enet	19	0.01	1.2e-01	-4.0	-5.3	8.6e-08	-0.03	0.18	0.54	FALSE
41	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARNT	0.06	0.02	lasso	3	0.02	1.4e-03	5.0	-5.3	1.3e-07	-0.05	0.01	0.89	FALSE
19	GTEx	Skin Sun Exposed Lower leg	SV2A	0.07	0.00	enet	15	0.02	6.0e-03	-1.4	-5.3	1.4e-07	-0.16	0.07	0.12	FALSE
34	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1orf54	0.04	0.04	lasso	2	0.03	2.0e-04	-5.4	5.3	1.4e-07	-0.10	0.12	0.58	FALSE
10	GTEx	Brain Cerebellar Hemisphere	RP11-316M1.12	0.31	0.37	lasso	4	0.39	4.5e-11	-4.1	5.3	1.5e-07	0.01	0.98	0.02	FALSE
18	GTEx	Skin Sun Exposed Lower leg	GABPB2	0.12	0.01	enet	16	0.04	1.8e-04	6.2	-5.2	1.7e-07	-0.03	0.14	0.10	FALSE
6	GTEx	Artery Tibial	ARNT	0.09	0.07	lasso	3	0.06	1.5e-05	5.0	-5.2	2.4e-07	-0.07	0.47	0.33	FALSE
33	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C1orf54	0.06	0.02	blup	17	0.03	2.5e-03	-5.4	5.1	2.7e-07	-0.10	0.02	0.19	FALSE