Hub : Genes

FCGR1A

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 YFS Blood 0.117 0.0365 0.0000 0.109 0.100 0.104 0.105 0.108 1.3e-33 6.9e-31 4.8e-32 1.5e-32 2.4e-33
2 TCGA Skin Cutaneous Melanoma 0.100 0.0590 0.0045 0.035 0.024 0.005 NA 0.036 4.2e-02 7.7e-02 2.3e-01 NA 3.9e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 1.5 2.4 2.5 -1.5 1.6
Bipolar Disorder or Schizophrenia 1.9 4.6 5.3 -2.0 2.3
Depressed Affect (Nagel 2018) 0.7 1.6 2.8 -1.7 0.6
Depression (Nagel 2018) 1.4 2.1 3.3 -1.8 1.0
Intelligence (Savage-Jansen 2018) 0.3 1.0 1.8 1.4 -0.4
Neuroticism (Nagel 2018) 4.3 10.0 10.3 -3.1 3.2
Schizophrenia (2018) 1.1 2.3 2.8 -1.3 1.7
Schizophrenia vs Biploar Disorder 0.9 1.2 2.3 0.4 -1.5
Worry (Nagel 2018) 4.3 9.1 13.2 -2.2 3.6
Alzheimer’s Disease (in mother) 0.0 0.0 0.1 -0.2 0.2
Alzheimer’s Disease (in father) 1.9 2.0 3.2 1.8 -0.9
Alzheimer’s Disease (including proxy) 1.0 1.5 2.1 0.9 -1.4
Crohns Disease (2017) 0.1 0.3 0.6 0.0 0.8
Irritable Bowel Disease (IBD) 0.3 0.7 1.4 0.0 1.2
Ulcerative Colitis (UC) 0.4 0.7 1.3 -0.2 1.1
Major Depression (MDD) 0.4 0.5 1.0 -0.2 -1.0
Reaction Time 2.1 4.0 4.2 -2.0 2.0
Verbal and Numeric Reasoning (VNR) 1.2 2.8 4.8 2.2 -0.9
Breast Cancer 1.5 3.7 7.0 0.6 -2.6
Ovarian Cancer 0.1 0.2 0.2 -0.4 0.5
Prostate Cancer 0.5 0.7 0.9 0.7 -0.9
Age at First Birth 0.3 0.5 0.6 0.6 -0.8
Bipolar Disorder (2011) 0.2 0.2 0.4 0.0 0.6
Body Mass Index (BMI) (2010) 1.4 2.0 3.4 0.7 -1.8
Coronary Artery Disease (CAD) 1.6 2.0 2.0 -1.4 1.4
Crohns Disease (2012) 0.2 0.4 0.8 -0.0 0.9
Mean Putamen Volume 2.7 3.1 3.5 -1.9 1.6
Fasting Glucose 1.4 1.6 2.1 -1.4 1.1
HbA1C 1.1 1.2 2.4 -1.5 -0.3
HDL Cholesterol 0.8 1.4 1.8 1.0 -1.4
LDL Cholesterol 0.5 0.8 1.5 0.2 -1.2
Lupus 2.9 4.4 6.5 -2.5 1.5
Neuroticism (2016) 7.0 10.1 11.4 -3.0 3.4
Primary Biliary Cirrhosis 1.4 2.0 2.1 -1.4 1.4
Rheumatoid Arthritis 0.1 0.2 0.2 0.5 -0.4
Schizophrenia (2014) 2.2 4.8 5.6 -2.4 2.0
Triglycerides 0.1 0.2 0.2 -0.5 0.3
Type 2 Diabetes (T2D) (2012) 6.1 7.1 8.0 -2.8 2.5
Ulcerative Colitis 2.1 3.0 3.9 -1.4 2.0
Blood Eosinophil Count 0.0 0.1 0.3 -0.5 0.1
Blood Platelet Count 0.1 1.0 2.1 -1.4 -0.1
Blood Red Count 0.4 3.4 4.3 1.6 -2.1
Blood White Count 1.3 9.5 10.7 3.3 -2.9
Heel T-Score 5.6 44.2 49.3 -6.2 7.0
BMI 0.2 1.2 2.3 -1.5 -0.4
Height 2.3 44.5 86.1 -1.7 9.3
Waist Hip Ratio (WHR) 0.9 3.8 5.1 -2.3 1.6
Systolic Blood Pressure 0.4 2.0 2.8 -1.7 1.1
Smoking Status 1.1 2.7 3.4 -1.8 1.4
Allergy or Eczema 0.2 0.4 0.5 -0.6 0.7
Cardiovascular Disease 0.7 2.3 4.4 -2.1 0.4
Hypothyroidism (self reported) 3.3 7.6 10.7 -2.1 3.3
Respiratory disease 0.4 1.0 1.4 1.2 -0.7
Type 2 Diabetes (T2D) (2018) 2.0 3.7 3.8 -2.0 1.9
Lung FEV1/FVC ratio 1.5 7.8 15.3 0.5 -3.9
Lung FVC 0.6 3.0 5.3 -2.3 0.9
Neuroticism 3.2 7.8 9.0 -2.6 3.0
Chronotype (morning person) 1.1 2.6 5.2 0.0 2.3
Hair Pigment 0.6 15.9 25.0 2.6 -5.0
Tanning 0.1 1.1 1.2 1.0 -1.1
Hand grip strength (left) 0.4 1.1 1.8 -0.7 1.3
Number of treatments/medications taken 0.1 0.2 0.4 -0.6 0.0
Average weekly spirits intake 0.6 0.8 0.8 0.9 -0.9
Sensitivity / hurt feelings 3.1 5.3 8.0 -1.6 2.8
Frequency of depressed mood in last 2 weeks 0.3 0.4 0.7 -0.8 0.4
Hearing difficulty/problems: Yes 0.0 0.1 0.1 0.2 0.3
Relative age of first facial hair 0.7 1.5 2.9 -0.2 1.7
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.2 0.2 -0.5
Ever used hormone-replacement therapy (HRT) 2.9 3.6 4.9 2.2 -1.6
Ever had hysterectomy (womb removed) 1.2 1.3 1.6 1.0 -1.3
Systolic blood pressure, automated reading 0.2 0.6 0.7 -0.8 0.7
Eye problems/disorders: Diabetes related eye disease 0.0 0.0 0.0 0.1 -0.1
Angina 2.1 2.8 4.4 -1.1 2.1
Medication for hormone replacement therapy 0.4 0.4 0.8 0.1 -0.9
Vitamin and mineral supplements 0.2 0.3 0.5 -0.3 -0.7
Supplements: Zinc 0.6 0.7 1.1 1.0 0.5
Medication: Co-codamol 0.1 0.2 0.2 -0.4 -0.4
Medication: Metformin 1.1 1.6 1.8 -1.2 1.3
Diabetes (father) 0.7 0.9 1.0 -1.0 0.8
Diabetes (mother) 1.7 2.2 4.1 -2.0 0.6
Severe depression (siblings) 0.3 0.3 0.4 -0.4 -0.7
Pack years adult smoking proportion 3.0 4.5 6.2 1.7 -2.5
Impedance of leg (right) 0.4 2.0 4.0 0.1 2.0
Leg fat-free mass (left) 1.8 9.6 13.8 -2.4 3.7
Trunk fat percentage 3.8 15.1 21.6 -2.9 4.6
Hand grip strength (right) 0.2 0.6 1.3 -0.1 1.1
Townsend deprivation index at recruitment 0.3 0.4 0.7 0.3 -0.9
Current tobacco smoking 0.2 0.4 0.4 -0.6 0.6
Average weekly fortified wine intake 1.1 1.3 2.0 0.8 -1.4
Maternal smoking around birth 0.4 0.6 0.8 0.9 0.6
Fed-up feelings 0.4 0.7 1.4 -1.2 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 0.7 -0.0 -0.8
Relative age voice broke 0.5 0.7 1.2 -1.1 0.5
Taking other prescription medications 0.2 0.4 0.6 0.4 0.8
Age when periods started (menarche) 0.5 1.2 1.4 1.2 -1.0
Bilateral oophorectomy (both ovaries removed) 1.1 1.3 2.1 0.7 -1.5
Heel bone mineral density (BMD) T-score, automated (left) 2.3 5.2 5.2 -2.3 2.3
Tinnitus: Yes, but not now, but have in the past 0.6 0.6 1.2 -0.1 1.1
Qualifications: CSEs or equivalent 1.9 2.5 3.5 -1.9 1.3
Serious illness, injury or assault to yourself 0.0 0.0 0.0 0.2 -0.1
High blood pressure 1.3 3.6 7.0 -2.6 -0.4
Hayfever, allergic rhinitis or eczema 1.4 3.0 3.7 -1.9 1.5
Multivitamins +/- minerals 0.7 0.9 1.7 -0.3 1.3
Stomach or abdominal pain in last month 1.6 2.0 3.3 -1.8 0.8
Supplements: Glucosamine 1.2 1.6 2.2 1.0 -1.5
Diverticular disease/diverticulitis (self-reported) 1.7 2.0 3.8 1.9 -0.5
Medication: Atenolol 0.3 0.4 0.9 0.9 0.0
Medication: Levothyroxine sodium 0.6 1.1 2.2 0.2 1.5
Sitting height 0.9 6.4 12.6 -0.5 3.5
Chronic bronchitis/emphysema (father) 1.2 1.4 2.4 1.6 -0.6
High blood pressure (mother) 1.0 1.3 2.5 -1.6 -0.5
Body mass index (BMI) 0.1 0.5 0.6 -0.6 -0.8
Impedance of leg (left) 0.2 1.1 1.8 0.7 1.4
Leg predicted mass (left) 1.6 8.5 12.3 -2.2 3.5
Trunk fat mass 3.2 13.6 20.0 -2.7 4.5
Waist circumference 0.3 1.1 1.2 -1.1 1.0
Number of incorrect matches in round 0.6 1.0 1.7 -1.3 0.6
Past tobacco smoking 0.7 1.3 1.8 0.9 -1.3
Alcohol usually taken with meals 0.2 0.3 0.6 -0.2 0.8
Nervous feelings 2.1 3.8 5.4 -1.5 2.3
Frequency of tenseness / restlessness in last 2 weeks 2.1 3.3 4.0 -2.0 1.6
Hearing difficulty/problems with background noise 0.0 0.0 0.0 -0.1 0.2
Hair/balding pattern: Pattern 2 0.0 0.0 0.1 -0.2 0.1
Had menopause 1.2 1.4 2.9 1.7 -0.2
Had other major operations 1.8 2.2 3.1 1.1 -1.8
Forced vital capacity (FVC) 4.9 18.9 23.5 -3.8 4.8
Heel bone mineral density (BMD) T-score, automated (right) 1.5 3.4 3.5 -1.8 1.9
Ever unenthusiastic/disinterested for a whole week 0.7 0.8 1.6 -0.1 -1.3
Qualifications: None of the above 3.1 6.6 10.8 1.6 -3.3
Financial difficulties in last 2 years 1.1 1.4 2.8 0.3 -1.7
Mouth/teeth dental problems 0.3 0.4 0.8 -0.2 -0.9
Heart attack 0.1 0.1 0.2 -0.4 0.3
Allergy 0.9 2.1 2.2 1.4 -1.5
Pain all over the body in last month 2.0 2.1 3.9 0.6 -2.0
Diabetes (self-reported) 0.2 0.4 0.5 -0.7 0.5
Hayfever/allergic rhinitis (self-reported) 1.7 2.2 2.8 -1.7 1.3
Medication: Ramipril 1.3 1.6 2.7 0.7 -1.6
Medication: Simvastatin 0.1 0.1 0.1 -0.3 -0.4
Fluid intelligence score 0.1 0.3 0.3 0.5 0.6
Illnesses of siblings 2.7 3.8 4.8 2.2 -1.6
Neuroticism score 0.8 1.6 2.0 -1.1 1.4
Weight 1.2 6.0 8.9 -1.8 3.0
Impedance of arm (right) 9.2 42.8 74.0 -3.4 8.6
Arm fat percentage (right) 2.2 8.6 11.3 -2.4 3.4
Trunk fat-free mass 0.1 0.4 0.8 0.1 0.9
Hip circumference 0.3 1.4 2.3 -0.7 1.5
Time employed in main current job 0.9 1.1 1.4 0.9 -1.2
Alcohol intake versus 10 years previously 0.1 0.2 0.2 -0.4 -0.4
Father’s age at death 0.0 0.1 0.1 -0.3 -0.2
Worrier / anxious feelings 0.6 1.1 2.0 -0.4 1.4
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 0.9 0.4 -1.0
Falls in the last year 0.9 1.2 2.2 -1.5 0.5
Hair/balding pattern: Pattern 3 3.8 5.7 9.7 1.3 -3.1
Number of live births 1.1 1.6 2.6 -0.7 1.6
Forced expiratory volume in 1-second (FEV1) 2.6 8.8 9.0 -3.0 2.9
Pulse rate 0.4 0.7 1.3 -1.2 0.2
Happiness 2.3 2.8 3.9 -2.0 1.3
Noisy workplace 0.7 0.9 1.7 -1.3 0.3
Qualifications: A levels/AS levels or equivalent 0.3 0.7 1.0 1.0 -0.5
Serious illness, injury or assault of a close relative in last 2 years 2.7 3.1 3.2 1.8 -1.7
Mouth/teeth dental problems: Dentures 0.4 0.7 1.4 1.2 -0.2
Asthma 0.1 0.2 0.3 0.6 0.0
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 1.1 0.7 -1.0
Medication: Cholesterol lowering 0.7 1.1 1.7 -1.3 0.6
Depression (self-reported) 0.1 0.1 0.1 0.3 -0.2
Medication: Lansoprazole 0.1 0.1 0.2 0.3 0.4
Prospective memory result 0.4 0.5 0.9 -1.0 0.3
Lung cancer (father) 0.9 1.0 1.7 0.6 -1.3
Illnesses of mother 1.0 1.3 2.3 1.5 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 1.6 5.1 5.5 -2.2 2.3
Pulse wave Arterial Stiffness index 0.1 0.1 0.2 0.3 -0.4
Impedance of arm (left) 8.2 38.0 66.1 -3.1 8.1
Arm fat mass (right) 1.9 7.9 9.7 -2.5 3.1
Trunk predicted mass 0.1 0.5 0.9 0.1 1.0
Standing height 4.1 40.2 72.4 -2.8 8.5
Length of working week for main job 1.3 1.4 2.2 0.8 -1.5
Exposure to tobacco smoke at home 0.6 0.7 1.2 -0.5 -1.1
Breastfed as a baby 0.4 0.5 1.0 1.0 -0.1
Tense / ‘highly strung’ 4.5 7.5 7.5 -2.7 2.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 0.7 -0.9 -0.3
Hair/balding pattern: Pattern 4 0.0 0.1 0.2 -0.1 -0.5
Birth weight of first child 0.9 1.7 2.6 -0.8 1.6
Peak expiratory flow (PEF) 0.8 1.9 3.2 -1.8 0.8
Pulse wave reflection index 1.4 1.8 2.2 1.5 -1.1
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.1 -0.1 -1.1
Loud music exposure frequency 1.1 1.2 1.5 0.9 -1.2
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 1.5 0.3 1.2
Mouth/teeth dental problems: Bleeding gums 0.9 1.2 1.5 -1.2 1.0
Blood clot in the leg (DVT) 0.4 0.5 0.9 -1.0 0.2
Medication: Paracetamol 0.2 0.4 0.8 0.0 -0.9
Headache pain in last month 0.1 0.2 0.3 -0.5 0.5
Medication for cholesterol, blood pressure or diabetes 1.2 1.9 3.4 1.9 -0.6
Glaucoma (self-reported) 3.3 3.9 4.3 2.1 -1.9
Gout (self-reported) 2.2 3.1 4.2 -2.0 1.4
Hypothyroidism/myxoedema (self-reported) 3.6 7.0 11.0 -1.7 3.3
Medication: Amlodipine 0.3 0.5 0.9 -0.2 -1.0
Medication: Ventolin 100micrograms inhaler 2.0 2.6 3.2 -1.4 1.8
Birth weight 0.9 1.9 3.7 1.9 0.1
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.1 0.4 -0.2
High blood pressure (siblings) 1.4 2.1 2.3 -1.5 1.3
Forced vital capacity (FVC), Best measure 3.0 10.9 15.1 -2.6 3.9
Body fat percentage 2.0 7.8 10.7 -2.2 3.3
Leg fat percentage (right) 0.0 0.1 0.1 -0.3 -0.2
Arm fat-free mass (right) 0.0 0.1 0.1 0.3 -0.1
Exposure to tobacco smoke outside home 0.1 0.1 0.1 0.4 -0.2
Comparative body size at age 10 0.1 0.2 0.2 0.5 -0.2
Number of full brothers 0.1 0.1 0.1 0.4 0.2
Worry too long after embarrassment 0.6 1.0 1.7 -0.5 1.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 0.6 -0.0 -0.8
Wheeze or whistling in the chest in last year 0.3 0.5 1.1 -1.0 -0.2
Number of children fathered 1.3 1.4 2.2 -0.8 -1.5
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 1.2 -1.1 0.3
Age at first live birth 0.9 1.7 2.2 -1.5 1.1
Pulse wave peak to peak time 0.3 0.4 0.7 -0.4 0.8
Health satisfaction 1.5 1.9 1.9 -1.4 1.4
Shortness of breath walking on level ground 0.0 0.0 0.1 -0.3 0.1
Qualifications: College or University degree 1.0 3.3 5.2 -1.2 2.3
Eye problems/disorders: None of the above 0.4 0.5 0.9 -0.9 -0.3
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.4 -0.2 -0.6
Emphysema/chronic bronchitis 0.0 0.0 0.1 0.1 0.3
Medication for pain relief, constipation, heartburn 0.1 0.1 0.3 -0.1 0.5
Neck or shoulder pain in last month 0.5 0.7 0.8 -0.8 0.9
Medication: Blood pressure 1.0 1.7 3.4 -1.8 -0.0
Angina (self-reported) 2.4 3.1 4.5 -1.3 2.1
Migraine (self-reported) 0.2 0.2 0.4 0.6 0.1
Medication: Ibuprofen 0.5 0.5 0.9 0.4 -1.0
Medication: Allopurinol 0.3 0.4 0.8 -0.9 -0.1
Medication: Omeprazole 2.0 2.4 3.6 1.1 -1.9
Medication: Seretide 50 evohaler 2.9 3.3 4.9 2.2 -1.3
Mean time to correctly identify matches 0.6 1.1 1.3 -1.1 0.9
Heart disease (mother) 0.7 0.8 0.9 -0.9 0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.3 1.5 2.9 0.2 -1.7
Whole body fat mass 2.0 8.3 11.5 -2.2 3.4
Leg fat mass (right) 0.4 1.5 1.6 -1.2 1.2
Arm predicted mass (right) 0.0 0.1 0.2 0.4 -0.2
Pulse rate, automated reading 0.4 1.2 1.3 -1.0 1.1
Alcohol intake frequency. 0.2 0.4 0.7 -0.1 -0.8
Comparative height size at age 10 6.8 37.5 61.5 -3.7 7.8
Number of full sisters 0.0 0.1 0.1 0.3 0.2
Suffer from ‘nerves’ 2.2 3.5 5.7 -1.1 2.4
Overall health rating 0.8 1.8 2.7 -1.6 1.0
Chest pain or discomfort 1.0 1.4 2.0 -1.4 0.9
Had major operations 1.0 1.2 2.2 0.4 -1.5
Age at last live birth 0.3 0.5 0.9 -0.9 0.3
Family relationship satisfaction 0.5 0.6 1.1 -1.0 0.4
Leg pain on walking 0.7 0.9 1.5 -0.5 -1.2
Qualifications: NVQ or HND or HNC or equivalent 0.0 0.1 0.1 -0.3 0.2
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.4 0.1 -0.6
Illness, injury, bereavement, stress in last 2 years 0.7 0.9 0.9 -0.9 1.0
Medication: Aspirin 0.2 0.3 0.4 0.6 0.5
Supplements: Vitamin C 0.3 0.3 0.6 -0.0 0.8
Knee pain experienced in last month 0.3 0.5 0.7 0.5 -0.8
Hypertension (Self-reported) 1.0 2.9 5.3 -2.3 -0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 1.5 1.2 -0.6
Illnesses of father: Heart disease 0.2 0.3 0.6 -0.0 0.8
Illnesses of siblings: Diabetes 0.9 1.1 1.3 -0.9 1.2
Smoking status: Previous 0.7 1.1 1.6 -0.8 1.2
Forced expiratory volume in 1-second (FEV1), predicted 3.1 6.5 12.0 -0.9 3.5
Whole body fat-free mass 0.3 1.8 3.1 -0.7 1.8
Leg fat-free mass (right) 1.4 7.6 11.2 -2.0 3.4
Arm fat percentage (left) 2.0 8.0 10.4 -2.4 3.2
Average weekly red wine intake 3.4 5.0 6.4 -1.9 2.5
Handedness (chirality/laterality): Left-handed 1.1 1.3 2.2 -0.6 1.5
Mood swings 0.2 0.3 0.5 -0.3 -0.7
Loneliness, isolation 0.5 0.6 0.9 -0.9 0.6
Long-standing illness, disability or infirmity 0.1 0.2 0.4 0.0 0.6
Ever had bowel cancer screening 0.1 0.1 0.2 -0.3 -0.5
Diabetes diagnosed by doctor 0.4 0.7 0.9 -1.0 0.7
Ever had stillbirth, spontaneous miscarriage or termination 0.0 0.0 0.1 0.3 0.1
Friendships satisfaction 0.7 0.8 1.1 -1.0 0.8
Qualifications: nursing, teaching 0.5 0.7 1.4 0.2 1.2
Commuting to job workplace: Walk 0.4 0.5 0.8 0.3 0.9
Eye problems/disorders: Cataract 2.3 2.7 4.9 -0.7 2.2
Mouth/teeth dental problems: Mouth ulcers 0.7 1.2 1.5 -0.9 1.2
Medication for cholesterol 1.5 2.3 4.0 -0.7 2.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.1 2.5 4.6 -2.2 0.5
Back pain experienced in last month 0.1 0.1 0.2 -0.2 -0.5
Mineral and other dietary supplements 0.6 0.8 1.5 -1.2 0.4
Breast cancer (self-reported) 0.4 0.4 0.5 0.7 -0.6
Asthma (self-reported) 0.1 0.2 0.3 0.6 -0.3
Osteoporosis (self-reported) 2.7 3.4 3.6 -1.8 1.9
Osteoarthritis (self-reported) 8.1 10.4 11.2 3.3 -3.1
Medication: Aspirin 0.2 0.2 0.4 0.1 0.6
Medication: Gliclazide 0.3 0.3 0.4 -0.6 0.5
Illnesses of father: None of the above (group 1) 0.2 0.3 0.6 -0.1 -0.8
Smoking status: Current 0.7 1.1 1.4 -1.2 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 0.5 -0.6 -0.7
Whole body water mass 0.3 1.7 3.0 -0.7 1.7
Leg predicted mass (right) 1.4 7.5 11.1 -2.0 3.3
Arm fat mass (left) 1.5 6.3 7.9 -2.2 2.8
Number of self-reported non-cancer illnesses 0.1 0.1 0.2 0.1 -0.4
Average weekly champagne plus white wine intake 1.3 1.9 3.1 -0.8 1.8
Miserableness 0.0 0.0 0.0 -0.2 0.1
Guilty feelings 1.7 2.6 3.5 -1.3 1.9
Wears glasses or contact lenses 0.3 0.3 0.5 -0.4 -0.7
Ever taken oral contraceptive pill 1.3 1.4 2.6 -1.6 0.5
Hearing aid user 0.2 0.2 0.4 0.1 0.6
Mother’s age at death 0.2 0.2 0.5 -0.7 0.1
Financial situation satisfaction 0.8 1.0 1.2 -1.1 0.9
Tinnitus: Yes, now most or all of the time 1.6 1.9 3.5 -1.9 0.6
Commuting to job workplace: Public transport 0.2 0.2 0.4 -0.6 -0.2
Eye problems/disorders: Glaucoma 4.2 5.0 5.0 2.2 -2.2
Medication: Blood pressure 0.7 1.3 2.7 0.2 -1.6
Pain type(s) experienced in last month: Hip pain 0.4 0.5 0.9 0.5 -0.9
Supplements: Fish oil (including cod liver oil) 0.8 1.1 1.9 1.4 -0.5
High cholesterol (Self-reported) 0.2 0.4 0.5 0.7 -0.5
Medication: Bendroflumethiazide 1.8 2.7 5.3 0.3 -2.3
Medication: Paracetamol 1.1 1.7 2.9 0.7 -1.7
Medication: Lisinopril 2.6 3.4 6.5 -2.5 0.5
Medication: Atorvastatin 0.1 0.1 0.1 0.1 -0.4
Illnesses of father: High blood pressure 4.7 5.8 8.7 -3.0 1.7
Alcohol drinker status: Never 1.2 1.5 2.1 0.9 -1.5
Ever smoked 0.8 1.3 2.1 -0.8 1.5
Basal metabolic rate 0.5 3.0 4.9 -1.1 2.2
Leg fat percentage (left) 0.1 0.2 0.4 -0.1 -0.6
Arm fat-free mass (left) 0.0 0.1 0.2 -0.0 0.4
Number of operations (self-reported) 3.6 5.4 8.2 1.6 -2.9
Average weekly beer plus cider intake 0.4 0.5 1.0 -1.0 0.2
Irritability 0.5 0.8 1.6 -1.2 0.2
Risk taking 1.1 1.6 2.9 -0.5 1.7
Ever had prostate specific antigen (PSA) test 0.5 0.6 1.1 0.4 -1.0
Fractured/broken bones in last 5 years 0.2 0.2 0.4 0.3 0.6
Age started oral contraceptive pill 0.3 0.4 0.7 0.3 0.9
Diastolic blood pressure, automated reading 0.1 0.2 0.3 -0.5 0.4
Ever depressed for a whole week 0.2 0.3 0.5 -0.7 0.0
Unable to work because of sickness or disability 0.5 0.6 1.0 -1.0 -0.5
Commuting to job workplace: Cycle 1.3 1.6 1.7 1.3 -1.2
Myopia 0.7 1.1 2.1 -1.4 -0.1
Vascular/heart problems diagnosed by doctor 0.9 2.4 4.7 2.2 0.3
Cholesterol lowering medication 0.8 1.2 1.4 1.2 -1.0
Medication: Omeprazole (e.g. Zanprol) 2.6 3.2 3.5 1.7 -1.9
Pain experienced in last month 1.1 1.9 3.2 -0.8 1.8
Supplements: Calcium 1.7 1.9 3.6 1.9 0.5
Basal cell carcinoma (self-reported) 0.3 0.3 0.5 0.3 0.7
Heart attack/myocardial infarction (self-reported) 0.2 0.3 0.3 -0.5 0.5
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 1.2 -1.1 0.2
Heart disease (siblings) 0.4 0.5 0.9 0.9 -0.2
Alcohol drinker status: Previous 0.3 0.3 0.6 -0.8 0.0
Pack years of smoking 3.4 5.1 6.8 1.8 -2.6
Impedance of whole body 3.6 18.1 32.6 -1.9 5.7
Leg fat mass (left) 0.3 1.3 1.3 -1.1 1.1
Arm predicted mass (left) 0.0 0.1 0.1 -0.1 0.3