[Hub]/) : Traits : Impedance of whole body :

chr19:16,462,417-20,451,172

Best TWAS P=6.87e-18 · Best GWAS P=2.57e-16 conditioned to 0.0638

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GATAD2A 0.13 0.30 lasso 7 0.29 2.4e-35 5.6 -6.2 7.1e-10 -0.71 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex HAPLN4 0.07 0.10 lasso 6 0.10 5.3e-12 8.2 8.1 4.1e-16 0.99 0.01 0.99 FALSE
3 CommonMind Brain Pre-frontal Cortex KIAA1683 0.09 0.06 enet 14 0.10 6.6e-12 -5.6 6.5 7.4e-11 0.01 0.02 0.98 FALSE
4 GTEx Adipose Subcutaneous KIAA1683 0.14 0.09 enet 6 0.16 2.5e-13 -6.3 7.4 1.5e-13 0.00 0.02 0.98 FALSE
5 GTEx Adipose Subcutaneous HAUS8 0.11 0.09 lasso 3 0.08 5.4e-07 7.2 -7.1 1.4e-12 -0.04 0.12 0.87 FALSE
6 GTEx Adipose Visceral Omentum HAUS8 0.15 0.12 lasso 2 0.12 7.0e-07 7.1 -6.2 5.7e-10 -0.05 0.10 0.89 FALSE
7 GTEx Adrenal Gland KIAA1683 0.26 0.05 enet 21 0.19 1.7e-07 -4.4 6.2 4.6e-10 0.03 0.05 0.91 FALSE
8 GTEx Artery Aorta HAUS8 0.18 0.12 lasso 2 0.09 7.3e-06 7.1 -7.1 9.0e-13 -0.04 0.11 0.88 FALSE
9 GTEx Artery Tibial MAU2 0.07 0.05 lasso 4 0.05 1.3e-04 5.5 5.3 1.3e-07 0.57 0.45 0.23 FALSE
10 GTEx Artery Tibial KIAA1683 0.16 0.08 enet 11 0.15 8.2e-12 -6.3 6.2 7.2e-10 0.02 0.43 0.57 FALSE
11 GTEx Artery Tibial HAUS8 0.16 0.02 lasso 7 0.02 4.7e-03 7.1 -7.5 5.4e-14 -0.04 0.14 0.82 FALSE
12 GTEx Artery Tibial CTD-3032J10.3 0.14 0.01 lasso 5 0.01 6.4e-02 7.6 -7.8 8.8e-15 0.01 0.01 0.88 FALSE
13 GTEx Brain Cerebellar Hemisphere HAUS8 0.44 0.15 lasso 7 0.11 8.1e-04 7.2 -6.8 1.1e-11 -0.03 0.14 0.52 FALSE
14 GTEx Brain Cerebellum SUGP2 0.15 -0.01 enet 27 0.00 2.3e-01 6.1 6.4 1.3e-10 0.63 0.05 0.43 FALSE
15 GTEx Brain Cerebellum PBX4 0.20 0.09 lasso 6 0.13 9.9e-05 5.9 5.5 3.5e-08 0.65 0.22 0.24 FALSE
16 GTEx Breast Mammary Tissue KIAA1683 0.17 0.10 lasso 5 0.07 1.2e-04 -4.5 5.6 1.8e-08 0.03 0.10 0.89 FALSE
17 GTEx Cells Transformed fibroblasts LPAR2 0.04 0.05 lasso 2 0.04 5.5e-04 6.2 -6.4 1.9e-10 -0.70 0.13 0.50 FALSE
18 GTEx Cells Transformed fibroblasts KIAA1683 0.14 0.16 lasso 2 0.15 1.2e-11 -6.3 7.0 3.7e-12 0.01 0.38 0.62 FALSE
19 GTEx Cells Transformed fibroblasts HAUS8 0.12 0.05 enet 19 0.05 1.0e-04 7.1 -5.8 5.4e-09 -0.01 0.16 0.78 FALSE
20 GTEx Colon Sigmoid KIAA1683 0.15 0.09 lasso 6 0.09 5.1e-04 -4.5 6.5 9.0e-11 0.03 0.03 0.90 FALSE
21 GTEx Colon Transverse KIAA1683 0.15 0.02 lasso 3 0.02 3.3e-02 -4.5 6.5 1.2e-10 0.02 0.01 0.98 FALSE
22 GTEx Colon Transverse YJEFN3 0.09 0.09 lasso 3 0.07 4.3e-04 7.5 -7.8 4.7e-15 -0.89 0.04 0.90 FALSE
23 GTEx Esophagus Mucosa LPAR2 0.08 0.03 lasso 2 0.01 1.1e-01 5.1 -5.2 2.2e-07 -0.67 0.09 0.74 FALSE
24 GTEx Esophagus Mucosa AC068499.10 0.16 0.07 lasso 5 0.08 6.7e-06 -5.6 -6.4 1.9e-10 0.02 0.66 0.08 FALSE
25 GTEx Esophagus Muscularis MYO9B 0.13 0.02 lasso 5 0.05 9.5e-04 5.3 -7.8 7.3e-15 -0.03 0.03 0.96 TRUE
26 GTEx Esophagus Muscularis KIAA1683 0.10 0.04 lasso 3 0.06 1.1e-04 -6.3 7.5 5.1e-14 0.01 0.01 0.99 FALSE
27 GTEx Esophagus Muscularis HAUS8 0.20 0.11 lasso 4 0.09 5.1e-06 7.2 -6.5 8.0e-11 -0.04 0.16 0.80 FALSE
28 GTEx Heart Atrial Appendage KIAA1683 0.15 0.03 lasso 5 0.10 2.4e-05 7.1 6.4 1.7e-10 0.04 0.01 0.96 FALSE
29 GTEx Heart Left Ventricle KIAA1683 0.20 0.03 lasso 7 0.15 2.9e-08 -4.5 5.7 1.5e-08 0.03 0.01 0.98 FALSE
30 GTEx Lung LPAR2 0.07 0.09 lasso 3 0.05 9.9e-05 6.2 -5.8 5.0e-09 -0.71 0.60 0.33 FALSE
31 GTEx Muscle Skeletal SUGP1 0.11 0.06 lasso 7 0.07 9.5e-08 8.2 -7.8 7.1e-15 -0.95 0.01 0.99 FALSE
32 GTEx Muscle Skeletal HAUS8 0.15 0.10 lasso 4 0.08 1.6e-08 7.2 -7.4 1.5e-13 -0.03 0.16 0.84 FALSE
33 GTEx Nerve Tibial LPAR2 0.14 0.05 lasso 5 0.06 2.3e-05 6.2 -5.2 2.4e-07 -0.67 0.68 0.07 FALSE
34 GTEx Nerve Tibial MYO9B 0.29 0.16 enet 30 0.20 6.7e-14 6.2 5.3 1.0e-07 0.03 0.99 0.01 FALSE
35 GTEx Nerve Tibial KIAA1683 0.25 0.22 lasso 9 0.28 5.2e-20 7.1 7.3 2.1e-13 0.01 0.00 1.00 FALSE
36 GTEx Pituitary OCEL1 0.53 0.07 lasso 10 0.24 1.2e-06 -3.0 5.6 1.7e-08 -0.01 0.15 0.05 TRUE
37 GTEx Pituitary KIAA1683 0.43 0.25 lasso 3 0.17 3.9e-05 7.0 7.0 2.5e-12 0.02 0.00 0.97 FALSE
38 GTEx Prostate KIAA1683 0.20 0.27 lasso 1 0.23 1.8e-06 -6.3 6.3 2.8e-10 0.01 0.21 0.33 FALSE
39 GTEx Skin Not Sun Exposed Suprapubic KIAA1683 0.16 0.05 enet 12 0.06 3.5e-04 -6.3 6.0 1.6e-09 0.03 0.05 0.94 FALSE
40 GTEx Skin Sun Exposed Lower leg KIAA1683 0.09 0.04 enet 9 0.06 1.0e-05 -6.3 5.3 9.0e-08 0.03 0.39 0.53 FALSE
41 GTEx Spleen LPAR2 0.27 0.06 lasso 6 0.04 2.7e-02 3.3 -5.5 2.9e-08 -0.72 0.04 0.69 FALSE
42 GTEx Spleen ATP13A1 0.16 0.01 lasso 5 0.02 9.7e-02 5.4 5.4 7.0e-08 0.62 0.05 0.45 FALSE
43 GTEx Spleen KIAA1683 0.26 0.17 lasso 6 0.13 3.9e-04 -6.3 6.3 2.5e-10 0.01 0.19 0.45 FALSE
44 GTEx Stomach PLVAP 0.27 0.01 lasso 5 0.00 5.0e-01 7.4 6.2 5.3e-10 0.03 0.03 0.50 FALSE
45 GTEx Thyroid YJEFN3 0.05 0.02 lasso 3 0.02 1.2e-02 7.9 -7.4 1.4e-13 -0.85 0.05 0.79 FALSE
46 GTEx Vagina LRRC25 0.63 0.02 enet 2 0.04 5.3e-02 7.1 -7.1 1.2e-12 0.01 0.02 0.64 FALSE
47 GTEx Vagina CTD-2521M24.6 0.48 0.01 lasso 6 0.02 9.0e-02 2.8 -5.7 1.6e-08 -0.05 0.04 0.17 FALSE
48 GTEx Whole Blood TMEM161A 0.06 0.00 enet 2 0.00 1.4e-01 5.5 -5.5 4.7e-08 -0.63 0.16 0.23 FALSE
49 GTEx Whole Blood LPAR2 0.10 0.07 lasso 5 0.07 8.0e-07 6.2 -6.1 1.3e-09 -0.80 0.21 0.79 FALSE
50 GTEx Whole Blood OCEL1 0.13 0.02 lasso 4 0.08 1.2e-07 4.7 5.4 5.5e-08 0.01 0.97 0.00 FALSE
51 METSIM Adipose CILP2 0.04 0.03 lasso 5 0.07 2.7e-11 5.8 5.4 7.6e-08 0.60 0.18 0.81 FALSE
52 METSIM Adipose KIAA1683 0.21 0.24 enet 21 0.27 2.1e-40 -4.3 6.1 1.1e-09 0.04 0.84 0.16 FALSE
53 NTR Blood LPAR2 0.04 0.03 lasso 3 0.03 3.6e-11 6.2 -6.4 1.4e-10 -0.64 0.98 0.02 FALSE
54 NTR Blood PGPEP1 0.02 0.01 lasso 3 0.01 8.5e-05 -4.0 -5.2 2.1e-07 0.03 0.31 0.04 TRUE
55 ROSMAP Brain Pre-frontal Cortex MYO9B 0.11 0.01 lasso 8 0.07 5.4e-09 7.3 -5.6 2.0e-08 0.02 0.02 0.98 FALSE
56 ROSMAP Brain Pre-frontal Cortex KIAA1683 0.23 0.14 bslmm 409 0.24 1.4e-30 -6.3 7.3 2.6e-13 0.01 0.01 0.99 FALSE
57 ROSMAP Brain Pre-frontal Cortex JUND 0.17 0.17 lasso 5 0.20 2.7e-25 7.1 7.1 1.5e-12 0.01 0.00 1.00 FALSE
58 ROSMAP Brain Pre-frontal Cortex HAUS8 0.05 0.05 enet 7 0.05 7.1e-07 7.2 -7.2 8.3e-13 -0.03 0.14 0.86 FALSE
59 ROSMAP Brain Pre-frontal Cortex TSSK6 0.04 0.00 blup 346 0.01 1.1e-02 7.5 5.7 1.5e-08 0.77 0.04 0.90 FALSE
60 ROSMAP Brain Pre-frontal Cortex HAPLN4 0.05 0.03 enet 15 0.03 1.7e-04 6.1 8.6 6.9e-18 0.83 0.01 0.99 TRUE
61 YFS Blood GATAD2A 0.09 0.14 blup 365 0.14 7.5e-44 5.4 5.6 2.7e-08 0.59 1.00 0.00 FALSE
62 YFS Blood GMIP 0.10 0.06 enet 37 0.08 9.6e-24 -3.7 5.5 3.2e-08 0.48 1.00 0.00 FALSE
63 YFS Blood HAUS8 0.03 0.02 lasso 6 0.02 3.3e-07 6.4 -6.1 8.8e-10 -0.05 0.26 0.74 FALSE
64 YFS Blood KIAA1683 0.51 0.40 enet 65 0.46 9.9e-171 7.1 8.0 1.7e-15 0.00 0.00 1.00 TRUE
65 YFS Blood LPAR2 0.14 0.15 lasso 5 0.16 3.6e-48 6.1 -5.8 8.9e-09 -0.65 1.00 0.00 FALSE
66 The Cancer Genome Atlas Bladder Urothelial Carcinoma KIAA1683 0.05 0.04 enet 6 0.05 4.9e-05 -6.3 7.5 7.6e-14 0.02 0.01 0.97 FALSE
67 The Cancer Genome Atlas Bladder Urothelial Carcinoma YJEFN3 0.04 0.05 lasso 7 0.04 1.6e-04 7.8 -8.0 1.8e-15 -0.93 0.01 0.98 FALSE
68 The Cancer Genome Atlas Breast Invasive Carcinoma CILP2 0.02 0.02 blup 30 0.02 1.6e-04 7.8 7.5 6.3e-14 0.93 0.01 0.96 FALSE
69 The Cancer Genome Atlas Breast Invasive Carcinoma HAPLN4 0.04 0.07 lasso 4 0.06 1.3e-12 8.2 8.1 6.2e-16 0.98 0.01 0.99 FALSE
70 The Cancer Genome Atlas Breast Invasive Carcinoma HAUS8 0.05 0.06 enet 12 0.06 2.9e-12 7.2 -7.3 2.9e-13 -0.02 0.16 0.84 FALSE
71 The Cancer Genome Atlas Breast Invasive Carcinoma KIAA1683 0.04 0.02 blup 65 0.03 2.6e-07 -6.3 6.5 6.6e-11 0.02 0.05 0.95 FALSE
72 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma HAUS8 0.10 0.07 blup 55 0.07 3.2e-04 7.2 -6.9 4.5e-12 -0.05 0.06 0.88 FALSE
73 The Cancer Genome Atlas Colon Adenocarcinoma GATAD2A 0.04 0.03 blup 61 0.05 1.3e-03 5.3 7.1 1.0e-12 0.83 0.05 0.74 FALSE
74 The Cancer Genome Atlas Colon Adenocarcinoma HAPLN4 0.10 0.08 blup 38 0.11 8.5e-07 5.7 7.5 6.9e-14 0.89 0.03 0.96 FALSE
75 The Cancer Genome Atlas Colon Adenocarcinoma HAUS8 0.12 0.06 lasso 5 0.06 1.8e-04 7.1 -7.0 2.0e-12 0.00 0.10 0.83 FALSE
76 The Cancer Genome Atlas Colon Adenocarcinoma TSSK6 0.07 0.02 blup 32 0.04 2.9e-03 7.5 6.9 5.1e-12 0.85 0.01 0.83 FALSE
77 The Cancer Genome Atlas Glioblastoma Multiforme JUND 0.17 0.00 blup 57 0.03 5.4e-02 7.1 5.8 5.2e-09 0.05 0.01 0.63 FALSE
78 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GATAD2A 0.02 0.02 lasso 1 0.02 2.1e-03 5.6 5.6 2.7e-08 0.63 0.08 0.09 FALSE
79 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HAPLN4 0.07 0.05 lasso 7 0.07 2.9e-08 8.1 7.8 5.6e-15 0.93 0.01 0.99 FALSE
80 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HAUS8 0.08 0.07 blup 55 0.07 6.7e-08 7.1 -7.3 3.7e-13 -0.07 0.18 0.82 FALSE
81 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma KIAA1683 0.05 0.03 lasso 4 0.04 9.1e-06 -5.6 6.9 4.3e-12 0.04 0.03 0.97 FALSE
82 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GMIP 0.03 0.02 lasso 4 0.02 3.2e-03 6.2 6.4 1.9e-10 0.67 0.00 0.94 FALSE
83 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HAUS8 0.09 0.14 lasso 4 0.12 5.9e-14 7.2 -6.9 5.5e-12 -0.04 0.17 0.83 FALSE
84 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma JUND 0.05 0.04 lasso 1 0.04 4.3e-05 7.1 7.1 1.3e-12 -0.01 0.00 0.99 FALSE
85 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma KIAA1683 0.09 0.07 lasso 8 0.12 2.1e-13 -6.3 6.5 6.3e-11 0.01 0.08 0.92 FALSE
86 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma KIAA1683 0.13 0.02 blup 65 0.05 1.0e-03 7.0 7.2 8.5e-13 0.02 0.00 0.99 FALSE
87 The Cancer Genome Atlas Brain Lower Grade Glioma JUND 0.04 0.03 lasso 2 0.02 7.9e-04 7.1 7.2 6.2e-13 -0.01 0.00 0.99 FALSE
88 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA0892 0.03 0.01 lasso 7 0.02 6.3e-03 5.7 -5.6 2.4e-08 -0.64 0.07 0.09 FALSE
89 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA1683 0.16 0.11 lasso 6 0.11 2.9e-12 -6.3 7.5 6.6e-14 0.01 0.27 0.73 FALSE
90 The Cancer Genome Atlas Brain Lower Grade Glioma TSSK6 0.02 0.02 blup 33 0.02 1.8e-03 5.4 6.7 1.9e-11 0.80 0.03 0.55 FALSE
91 The Cancer Genome Atlas Lung Adenocarcinoma HAUS8 0.04 0.04 lasso 2 0.03 1.6e-04 7.1 -6.9 6.6e-12 -0.05 0.16 0.73 FALSE
92 The Cancer Genome Atlas Lung Adenocarcinoma KIAA1683 0.04 0.04 lasso 4 0.05 2.5e-06 -5.6 6.4 1.3e-10 0.03 0.46 0.50 FALSE
93 The Cancer Genome Atlas Lung Adenocarcinoma YJEFN3 0.03 0.03 blup 32 0.02 3.0e-03 7.5 -7.4 1.6e-13 -0.89 0.01 0.92 FALSE
94 The Cancer Genome Atlas Lung Squamous Cell Carcinoma HAUS8 0.06 0.04 enet 4 0.05 3.9e-06 5.3 -6.6 3.3e-11 -0.04 0.26 0.72 FALSE
95 The Cancer Genome Atlas Lung Squamous Cell Carcinoma KIAA1683 0.09 0.05 lasso 4 0.06 1.3e-07 7.1 7.8 5.0e-15 0.00 0.00 1.00 FALSE
96 The Cancer Genome Atlas Pancreatic Adenocarcinoma HAUS8 0.20 0.13 lasso 2 0.11 2.4e-05 7.2 -7.5 9.2e-14 -0.05 0.14 0.73 FALSE
97 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma HAUS8 0.21 0.11 enet 9 0.10 6.2e-05 -5.3 -5.2 2.4e-07 0.01 0.05 0.73 FALSE
98 The Cancer Genome Atlas Prostate Adenocarcinoma HAUS8 0.13 0.10 blup 55 0.11 7.8e-12 7.1 -6.8 8.0e-12 -0.04 0.18 0.82 FALSE
99 The Cancer Genome Atlas Prostate Adenocarcinoma KIAA1683 0.06 0.02 blup 65 0.04 3.2e-05 -4.5 5.7 1.1e-08 0.01 0.06 0.91 FALSE
100 The Cancer Genome Atlas Prostate Adenocarcinoma MYO9B 0.14 0.07 blup 103 0.10 5.0e-11 7.6 -5.4 8.0e-08 0.04 0.01 0.99 FALSE
101 The Cancer Genome Atlas Prostate Adenocarcinoma OCEL1 0.16 0.05 blup 53 0.10 1.6e-10 4.6 5.6 2.1e-08 0.03 0.00 0.97 FALSE
102 The Cancer Genome Atlas Prostate Adenocarcinoma YJEFN3 0.04 0.05 lasso 2 0.05 4.3e-06 7.8 -7.8 6.4e-15 -0.95 0.01 0.99 FALSE
103 The Cancer Genome Atlas Soft Tissue Sarcoma HAPLN4 0.11 0.01 blup 38 0.02 2.7e-02 8.1 7.3 3.1e-13 0.92 0.01 0.87 FALSE
104 The Cancer Genome Atlas Soft Tissue Sarcoma KIAA1683 0.07 0.00 blup 64 0.01 4.5e-02 -4.1 6.5 7.4e-11 0.07 0.01 0.74 FALSE
105 The Cancer Genome Atlas Stomach Adenocarcinoma HAPLN4 0.08 0.03 blup 37 0.04 7.2e-04 8.1 7.0 2.3e-12 0.87 0.01 0.98 FALSE
106 The Cancer Genome Atlas Stomach Adenocarcinoma HAUS8 0.06 0.04 blup 55 0.04 1.0e-03 7.2 -7.2 4.2e-13 -0.05 0.04 0.49 FALSE
107 The Cancer Genome Atlas Testicular Germ Cell Tumors KIAA1683 0.17 0.06 blup 65 0.06 3.0e-03 -4.6 7.0 1.7e-12 0.03 0.01 0.88 FALSE
108 The Cancer Genome Atlas Thyroid Carcinoma HAPLN4 0.08 0.06 blup 37 0.09 1.8e-09 5.6 7.7 1.9e-14 0.88 0.02 0.98 FALSE
109 The Cancer Genome Atlas Thyroid Carcinoma HAUS8 0.04 0.06 lasso 2 0.05 2.2e-05 7.2 -7.6 3.8e-14 -0.03 0.04 0.95 FALSE
110 The Cancer Genome Atlas Thyroid Carcinoma KIAA0892 0.04 0.04 blup 43 0.02 4.1e-03 5.7 -5.4 8.4e-08 -0.62 0.42 0.24 FALSE
111 The Cancer Genome Atlas Thyroid Carcinoma KIAA1683 0.15 0.09 lasso 6 0.16 5.4e-15 7.0 7.5 8.0e-14 0.02 0.00 1.00 FALSE
112 The Cancer Genome Atlas Thyroid Carcinoma YJEFN3 0.08 0.06 blup 33 0.08 7.1e-08 7.8 -7.3 2.4e-13 -0.90 0.01 0.99 FALSE