TWAS hub - SUGP2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellum	0.1510	0.0790	0.0099	-0.009	NA	0.004	NA	-0.010	7.9e-01	NA	2.3e-01	NA	8.3e-01
2	ROSMAP	Brain Pre-frontal Cortex	0.0491	0.0193	0.0011	0.041	0.022	0.041	0.027	0.039	4.8e-06	0.00062	5.3e-06	2e-04	7.7e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Breast Cancer	13.1	31.6	62.9	-7.9	-0.5
Maternal smoking around birth	10.0	14.4	24.3	2.1	4.9
Bipolar Disorder or Schizophrenia	8.9	21.7	43.3	6.6	0.2
Schizophrenia (2014)	8.5	18.8	37.0	6.1	0.8
Mother’s age at death	8.5	10.6	11.3	-3.4	-3.1
Sensitivity / hurt feelings	7.1	12.2	24.2	4.9	0.5
Bipolar Disorder (2018)	6.2	9.8	19.6	4.4	-0.1
Schizophrenia (2018)	5.7	11.9	23.7	4.9	0.4
Blood Platelet Count	5.4	62.1	118.8	10.9	2.3
Breast cancer (self-reported)	5.3	6.3	8.1	2.8	2.1
Risk taking	5.1	7.4	11.3	3.4	1.9
Rheumatoid Arthritis	5.0	6.9	12.7	3.6	1.0
Worry (Nagel 2018)	4.8	10.2	19.0	4.4	1.2
Impedance of leg (left)	4.8	23.5	45.2	6.7	-1.3
Impedance of leg (right)	4.7	22.9	44.7	6.7	-1.0
Myopia	4.7	6.9	13.8	3.7	-0.1
Hearing difficulty/problems: Yes	4.5	6.8	12.6	-3.5	1.1
Comparative body size at age 10	4.5	12.4	23.2	-4.8	1.3
Neuroticism (Nagel 2018)	4.4	10.4	20.8	4.6	0.3
Mouth/teeth dental problems: Bleeding gums	4.4	5.6	10.2	-3.2	1.1
Prostate Cancer	4.3	6.1	12.0	3.5	0.3
Suffer from ‘nerves’	4.3	6.8	11.2	3.3	1.6
Impedance of whole body	4.1	20.9	41.3	6.4	-0.7
Medication: Co-codamol	4.0	4.6	5.3	2.0	2.3
Illnesses of siblings: Diabetes	4.0	5.0	6.7	1.8	-2.6
High cholesterol (Self-reported)	3.9	7.0	13.5	-3.7	0.7
Unable to work because of sickness or disability	3.6	4.6	4.8	2.2	2.1
Vitamin and mineral supplements	3.5	4.8	9.0	-3.0	-0.7
Glaucoma (self-reported)	3.5	4.1	6.5	-2.6	-1.3
Age at first live birth	3.5	6.3	10.1	-3.2	-1.6
Townsend deprivation index at recruitment	3.4	4.8	8.0	-2.8	1.2
Medication: Levothyroxine sodium	3.4	5.8	6.0	2.4	2.4
Nervous feelings	3.2	5.9	11.8	3.4	-0.1
Medication: Cholesterol lowering	3.1	4.8	8.5	-2.9	1.0
Had major operations	3.1	3.7	7.0	-2.6	0.6
Stomach or abdominal pain in last month	3.0	3.8	7.5	2.7	0.3
Hair/balding pattern: Pattern 3	3.0	4.4	6.5	-2.5	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.9	3.4	6.8	-2.6	-0.2
Supplements: Vitamin C	2.9	3.5	5.7	2.4	1.1
Taking other prescription medications	2.8	4.3	7.4	2.7	1.1
Angina (self-reported)	2.8	3.7	4.2	-1.8	2.0
Forced expiratory volume in 1-second (FEV1), predicted	2.8	5.8	9.4	3.1	-1.4
Angina	2.7	3.5	3.6	-1.8	1.9
Medication: Simvastatin	2.7	4.0	8.0	-2.8	0.1
Mouth/teeth dental problems: Mouth ulcers	2.7	4.3	7.0	2.6	-1.3
Alzheimer’s Disease (in father)	2.6	2.9	3.2	1.6	1.8
Financial situation satisfaction	2.6	3.2	6.1	-2.5	0.6
Depressed Affect (Nagel 2018)	2.5	5.2	9.7	3.1	0.9
Eye problems/disorders: Glaucoma	2.5	3.0	4.2	-2.0	-1.3
Pain type(s) experienced in last month: Hip pain	2.5	3.1	5.2	1.0	-2.3
Pain all over the body in last month	2.4	2.5	5.0	0.3	2.2
Exposure to tobacco smoke at home	2.4	2.7	2.9	1.7	1.6
Heart disease (siblings)	2.4	2.9	4.4	-1.2	2.1
Ovarian Cancer	2.3	3.0	3.8	-1.5	2.0
Body Mass Index (BMI) (2010)	2.3	3.1	5.1	-2.3	1.1
Impedance of arm (right)	2.3	10.6	20.0	4.5	-1.1
Pulse wave reflection index	2.3	2.8	5.3	-2.3	0.6
Serious illness, injury or assault to yourself	2.2	2.6	3.9	2.0	1.2
Impedance of arm (left)	2.2	10.4	20.6	4.5	-0.4
Neck or shoulder pain in last month	2.1	3.0	5.3	2.3	0.9
Blood Eosinophil Count	2.0	15.7	31.2	5.6	0.4
Neuroticism	2.0	4.8	9.4	3.1	-0.5
Qualifications: CSEs or equivalent	2.0	2.7	5.2	0.4	2.3
Ever unenthusiastic/disinterested for a whole week	2.0	2.4	4.7	0.3	2.2
Father’s age at death	2.0	2.7	3.8	-1.2	-2.0
Current tobacco smoking	1.9	3.0	3.2	1.8	1.7
Age at last live birth	1.9	2.8	5.0	-2.2	-0.8
Ulcerative Colitis (UC)	1.8	3.3	5.6	2.4	1.0
Hair/balding pattern: Pattern 2	1.8	2.3	4.4	2.1	-0.5
Alcohol intake versus 10 years previously	1.8	2.7	4.2	2.0	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.8	3.4	1.4	1.9
Overall health rating	1.8	3.8	4.4	2.1	1.8
Medication: Aspirin	1.8	2.3	4.6	-2.2	0.1
Smoking status: Current	1.8	2.8	3.2	1.8	1.5
Cardiovascular Disease	1.7	5.5	7.0	-2.0	2.6
Neuroticism score	1.7	3.6	7.2	2.7	0.2
Ever had bowel cancer screening	1.7	2.0	2.8	1.1	1.7
Hearing aid user	1.7	1.9	3.4	0.6	1.8
Respiratory disease	1.6	3.5	6.1	0.9	2.5
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	2.8	0.8	1.7
Worrier / anxious feelings	1.6	3.0	5.0	2.2	1.0
Medication: Paracetamol	1.6	2.6	4.1	2.0	1.1
Tinnitus: Yes, now most or all of the time	1.6	1.9	3.2	0.8	1.8
Medication: Atorvastatin	1.6	2.0	2.9	-1.7	1.1
Medication: Ramipril	1.5	2.0	3.8	1.9	0.3
Number of live births	1.5	2.1	3.8	0.7	1.9
Hypothyroidism/myxoedema (self-reported)	1.5	2.9	4.4	2.1	1.2
Migraine (self-reported)	1.5	1.8	3.6	-0.2	1.9
Chest pain or discomfort	1.5	2.1	2.4	1.4	1.6
Illnesses of father: None of the above (group 1)	1.5	1.8	3.1	0.7	-1.8
Miserableness	1.5	2.7	4.2	2.1	1.0
Average weekly beer plus cider intake	1.5	2.2	2.7	1.3	1.6
Fractured/broken bones in last 5 years	1.5	1.9	3.1	-0.8	-1.8
Reaction Time	1.4	2.7	4.3	1.0	-2.1
Mean Putamen Volume	1.4	1.6	3.1	1.7	0.4
Ever had hysterectomy (womb removed)	1.4	1.6	1.7	1.2	1.3
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.2	2.9	1.7	1.2
Medication: Aspirin	1.4	1.8	3.6	-1.9	0.1
Irritability	1.4	2.4	4.6	2.2	-0.4
Vascular/heart problems diagnosed by doctor	1.4	3.7	6.6	0.9	-2.6
BMI	1.3	7.3	14.1	-3.8	0.7
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	3.3	0.3	1.8
Fed-up feelings	1.3	2.3	4.6	2.1	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	2.2	1.1	1.5
Multivitamins +/- minerals	1.3	1.7	2.2	1.5	1.1
Diverticular disease/diverticulitis (self-reported)	1.3	1.5	1.6	1.2	1.3
Peak expiratory flow (PEF)	1.3	3.0	4.3	-1.2	-2.1
Headache pain in last month	1.3	2.3	2.5	1.6	1.4
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	2.9	1.7	-1.1
Illnesses of father: Heart disease	1.3	1.9	3.2	-1.8	0.7
Loneliness, isolation	1.3	1.8	1.9	1.4	1.3
Ulcerative Colitis	1.2	1.8	2.5	1.6	1.1
Blood Red Count	1.2	11.9	23.8	-4.9	-0.3
Waist Hip Ratio (WHR)	1.2	5.3	10.5	-0.1	3.2
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.4	0.5	1.6
Sitting height	1.2	8.5	16.7	4.1	-0.6
Body mass index (BMI)	1.2	5.0	9.8	-3.1	0.4
Pulse rate	1.2	2.1	2.9	1.7	1.1
Average weekly red wine intake	1.2	1.8	3.4	1.9	-0.5
Commuting to job workplace: Walk	1.2	1.3	1.8	-1.4	-0.9
Average weekly champagne plus white wine intake	1.2	1.6	2.4	-1.6	0.9
Irritable Bowel Disease (IBD)	1.1	2.5	4.7	2.2	0.6
Lupus	1.1	1.7	2.5	1.6	1.0
Hypothyroidism (self reported)	1.1	2.5	3.0	1.7	1.4
Waist circumference	1.1	4.0	6.1	-2.5	1.4
Asthma	1.1	2.2	3.4	1.0	1.9
Tense / ‘highly strung’	1.1	1.8	3.6	1.9	-0.2
Medication: Amlodipine	1.1	1.6	1.8	-1.4	1.1
Worry too long after embarrassment	1.1	1.9	3.6	0.5	-1.9
Asthma (self-reported)	1.1	2.2	3.5	0.9	1.9
Triglycerides	1.0	1.6	2.4	-0.9	1.5
Height	1.0	18.9	34.8	5.9	-1.7
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	1.5	-1.2	-0.8
Diabetes (father)	1.0	1.3	2.3	-0.5	-1.5
Relative age voice broke	1.0	1.5	1.8	1.1	1.4
High blood pressure	1.0	2.8	5.0	-0.8	2.2
Financial difficulties in last 2 years	1.0	1.4	2.6	0.4	1.6
Medication: Ventolin 100micrograms inhaler	1.0	1.2	1.7	0.9	1.3
High blood pressure (siblings)	1.0	1.5	2.8	0.4	1.7
Medication for pain relief, constipation, heartburn	1.0	1.7	3.2	-0.5	-1.8
Mean time to correctly identify matches	1.0	1.9	3.4	0.6	-1.9
Hypertension (Self-reported)	1.0	2.8	5.4	-0.5	2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	2.0	-1.4	0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	2.1	1.5	0.3
Medication: Lisinopril	1.0	1.3	2.6	-0.4	1.6
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	1.5	-1.0	1.2
HbA1C	0.9	1.0	1.3	-1.2	-0.7
Type 2 Diabetes (T2D) (2012)	0.9	1.0	1.2	1.1	0.9
Average weekly fortified wine intake	0.9	1.1	1.1	-1.1	1.0
Heart attack	0.9	1.2	2.3	1.5	0.3
Falls in the last year	0.9	1.2	2.0	1.4	-0.6
Medication: Seretide 50 evohaler	0.9	1.0	1.2	0.9	1.1
Pulse rate, automated reading	0.9	3.0	4.5	2.1	1.2
Depression (Nagel 2018)	0.8	1.2	1.5	1.2	0.9
Lung FEV1/FVC ratio	0.8	4.3	8.2	-0.6	-2.9
Chronotype (morning person)	0.8	1.8	2.1	-1.2	-1.5
Age when periods started (menarche)	0.8	1.9	3.5	1.9	0.6
Had other major operations	0.8	1.0	1.4	1.2	0.7
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	1.3	1.1	-1.1
Exposure to tobacco smoke outside home	0.8	1.1	2.0	0.4	1.4
Medication: Blood pressure	0.8	1.4	2.8	-0.1	1.7
Medication: Ibuprofen	0.8	1.0	1.6	1.2	0.6
Family relationship satisfaction	0.8	1.0	2.0	1.4	-0.1
Leg fat-free mass (right)	0.8	4.2	7.9	-2.8	0.7
Eye problems/disorders: Cataract	0.8	1.0	1.0	1.0	-1.0
Medication: Gliclazide	0.8	0.9	1.4	0.6	1.2
Leg predicted mass (right)	0.8	4.3	8.0	-2.8	0.7
Wears glasses or contact lenses	0.8	0.9	1.7	1.3	-0.1
Number of operations (self-reported)	0.8	1.2	2.1	-0.5	1.5
Diastolic blood pressure, automated reading	0.8	2.3	4.6	-0.3	2.1
Smoking Status	0.7	1.7	2.1	1.1	1.5
Leg fat-free mass (left)	0.7	3.7	6.7	-2.6	0.9
Hayfever, allergic rhinitis or eczema	0.7	1.4	2.8	0.3	-1.7
Medication: Atenolol	0.7	0.9	1.2	-0.8	1.1
Leg predicted mass (left)	0.7	3.7	6.7	-2.6	0.8
Illnesses of siblings	0.7	1.0	1.7	-0.5	-1.3
Depression (self-reported)	0.7	0.9	1.5	0.5	1.2
Medication: Lansoprazole	0.7	0.8	1.1	0.7	1.1
Breastfed as a baby	0.7	0.9	1.3	0.7	-1.1
Number of full brothers	0.7	0.9	1.0	0.9	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.5	1.2	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.7	1.3	-0.1
Eye problems/disorders: None of the above	0.7	0.8	1.6	-0.0	1.2
Medication: Omeprazole	0.7	0.8	1.0	-0.8	1.0
Knee pain experienced in last month	0.7	1.1	2.2	0.3	-1.5
Smoking status: Previous	0.7	1.0	2.0	-0.3	1.4
Osteoarthritis (self-reported)	0.7	0.9	1.7	1.3	-0.1
Medication: Paracetamol	0.7	1.1	2.0	1.4	0.5
Average weekly spirits intake	0.6	0.7	1.3	0.4	-1.1
Frequency of depressed mood in last 2 weeks	0.6	0.8	1.4	0.4	-1.2
Past tobacco smoking	0.6	1.1	2.2	-0.1	-1.5
Fluid intelligence score	0.6	1.3	2.6	-1.6	-0.2
Qualifications: A levels/AS levels or equivalent	0.6	1.3	1.4	-1.0	-1.2
Standing height	0.6	6.3	12.5	3.5	-0.4
Pulse wave peak to peak time	0.6	0.7	0.9	0.9	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	1.0	0.8	-1.0
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.1	-0.7	-1.0
Whole body fat-free mass	0.6	3.1	5.8	-2.4	0.7
Long-standing illness, disability or infirmity	0.6	0.9	1.6	-0.5	1.3
Diabetes diagnosed by doctor	0.6	0.9	1.5	-0.6	-1.2
Back pain experienced in last month	0.6	0.9	1.9	-1.4	0.1
Whole body water mass	0.6	3.2	6.1	-2.5	0.6
Commuting to job workplace: Cycle	0.6	0.8	1.4	-0.3	1.2
Pain experienced in last month	0.6	1.0	1.1	-1.0	-1.0
Alcohol usually taken with meals	0.5	0.9	1.7	0.1	-1.3
Hip circumference	0.5	2.1	3.9	-2.0	-0.6
Hair/balding pattern: Pattern 4	0.5	1.2	1.5	-1.0	1.2
Wheeze or whistling in the chest in last year	0.5	0.8	1.1	0.7	1.1
Guilty feelings	0.5	0.8	1.2	-1.1	-0.7
Ever taken oral contraceptive pill	0.5	0.5	1.0	-1.0	0.1
Medication: Blood pressure	0.5	0.9	1.8	-0.1	1.3
Alcohol drinker status: Never	0.5	0.6	1.1	0.2	1.0
Basal cell carcinoma (self-reported)	0.5	0.7	0.7	0.8	0.8
Heart attack/myocardial infarction (self-reported)	0.5	0.7	1.4	1.2	0.1
Verbal and Numeric Reasoning (VNR)	0.4	0.8	1.3	-1.1	-0.6
Neuroticism (2016)	0.4	0.6	1.0	1.0	-0.5
Primary Biliary Cirrhosis	0.4	0.6	0.9	0.6	-1.0
Blood White Count	0.4	3.1	4.3	2.1	1.4
Systolic Blood Pressure	0.4	2.2	3.0	1.1	1.7
Supplements: Zinc	0.4	0.5	0.8	-0.4	-0.9
Diabetes (mother)	0.4	0.5	0.9	0.9	0.4
Severe depression (siblings)	0.4	0.5	0.9	1.0	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	1.4	0.6	1.2
Supplements: Glucosamine	0.4	0.6	0.9	0.5	-0.9
Trunk fat-free mass	0.4	2.2	4.2	-2.1	0.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	2.1	0.9	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	0.8	-0.2	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.8	0.9	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	1.4	1.0	-1.2
Trunk predicted mass	0.4	2.3	4.3	-2.1	0.5
Ever highly irritable/argumentative for 2 days	0.4	0.5	0.5	0.7	0.7
Chronic bronchitis/emphysema (mother)	0.4	0.4	0.5	0.5	0.7
Arm fat-free mass (right)	0.4	2.0	3.1	-1.8	0.9
Health satisfaction	0.4	0.5	0.9	-0.1	1.0
Arm fat mass (left)	0.4	1.5	2.8	-1.7	0.4
Basal metabolic rate	0.4	2.4	4.5	-2.1	0.6
Age started oral contraceptive pill	0.4	0.5	0.9	0.9	-0.2
Ever depressed for a whole week	0.4	0.5	0.6	0.5	0.8
Cholesterol lowering medication	0.4	0.5	0.8	-0.9	0.5
Alzheimer’s Disease (including proxy)	0.3	0.4	0.8	0.2	0.9
Crohns Disease (2017)	0.3	0.7	1.4	1.2	-0.2
Age at First Birth	0.3	0.5	0.8	-0.3	-0.9
Crohns Disease (2012)	0.3	0.5	0.5	0.7	0.7
Allergy or Eczema	0.3	0.9	1.2	1.1	-0.7
Hand grip strength (left)	0.3	0.8	1.4	-1.2	-0.5
Pack years adult smoking proportion	0.3	0.5	0.7	0.8	0.5
Chronic bronchitis/emphysema (father)	0.3	0.4	0.6	-0.8	-0.5
High blood pressure (mother)	0.3	0.4	0.8	0.9	0.1
Number of incorrect matches in round	0.3	0.4	0.6	-0.8	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	0.9	0.9	-0.3
Hearing difficulty/problems with background noise	0.3	0.5	1.0	-1.0	0.3
Had menopause	0.3	0.3	0.6	-0.8	-0.3
Forced vital capacity (FVC)	0.3	1.3	1.9	1.4	-0.8
Allergy	0.3	0.7	1.0	-1.0	0.7
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.7	0.8	0.2
Noisy workplace	0.3	0.3	0.6	-0.1	0.8
Lung cancer (father)	0.3	0.4	0.7	0.9	-0.2
Pulse wave Arterial Stiffness index	0.3	0.3	0.6	-0.4	0.8
Arm fat mass (right)	0.3	1.4	2.5	-1.6	0.6
Blood clot in the leg (DVT)	0.3	0.4	0.8	0.9	-0.1
Forced vital capacity (FVC), Best measure	0.3	1.2	2.3	1.5	-0.2
Number of children fathered	0.3	0.4	0.6	0.3	0.8
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.5	0.7	-0.3
Emphysema/chronic bronchitis	0.3	0.4	0.7	0.8	0.3
Arm predicted mass (right)	0.3	1.6	2.4	-1.5	0.9
Leg pain on walking	0.3	0.4	0.8	0.2	-0.9
Arm fat percentage (left)	0.3	1.1	2.0	-1.4	0.4
Mood swings	0.3	0.6	1.2	1.1	-0.1
Friendships satisfaction	0.3	0.3	0.7	0.1	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	0.5	0.5	-0.7
Mineral and other dietary supplements	0.3	0.4	0.9	-0.1	-0.9
Osteoporosis (self-reported)	0.3	0.3	0.7	0.0	0.8
Arm fat-free mass (left)	0.3	1.5	2.4	-1.6	0.7
Arm predicted mass (left)	0.3	1.4	2.6	-1.6	0.5
LDL Cholesterol	0.2	0.3	0.6	0.2	0.8
Hair Pigment	0.2	4.3	8.6	-2.9	0.1
Tanning	0.2	2.3	3.1	1.2	1.8
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.4	-0.0	-0.6
Hand grip strength (right)	0.2	0.5	0.6	-0.8	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.3	0.7	0.1	0.8
Qualifications: None of the above	0.2	0.5	0.6	0.6	0.8
Diabetes (self-reported)	0.2	0.4	0.7	-0.3	-0.8
Weight	0.2	1.0	2.1	-1.4	0.1
Arm fat percentage (right)	0.2	1.0	2.0	-1.4	0.1
Time employed in main current job	0.2	0.3	0.5	0.7	-0.0
Length of working week for main job	0.2	0.2	0.5	0.7	0.1
Loud music exposure frequency	0.2	0.2	0.4	0.3	-0.6
Qualifications: College or University degree	0.2	0.6	0.8	-0.9	-0.6
Medication: Allopurinol	0.2	0.3	0.6	0.1	0.8
Alcohol intake frequency.	0.2	0.5	1.0	1.0	-0.2
Comparative height size at age 10	0.2	1.0	1.2	1.1	-0.9
Number of full sisters	0.2	0.3	0.5	0.2	0.7
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.3	-0.6	0.1
Qualifications: nursing, teaching	0.2	0.3	0.6	-0.8	0.1
Medication for cholesterol	0.2	0.3	0.6	-0.3	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	0.6	-0.7	-0.7
Number of self-reported non-cancer illnesses	0.2	0.3	0.7	-0.1	0.8
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.5	0.7	0.1
Medication: Bendroflumethiazide	0.2	0.2	0.3	0.5	0.4
Ever smoked	0.2	0.3	0.6	-0.1	0.8
Supplements: Calcium	0.2	0.3	0.5	0.7	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.5	0.7	-0.2
Pack years of smoking	0.2	0.3	0.5	0.7	0.1
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.6	-0.8	-0.1
Schizophrenia vs Biploar Disorder	0.1	0.2	0.2	0.5	-0.4
Alzheimer’s Disease (in mother)	0.1	0.2	0.2	-0.3	-0.5
Coronary Artery Disease (CAD)	0.1	0.2	0.2	-0.4	0.4
HDL Cholesterol	0.1	0.1	0.2	-0.4	-0.3
Heel T-Score	0.1	0.5	0.7	-0.5	0.8
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.2	-0.1	-0.5
Lung FVC	0.1	0.3	0.4	0.4	0.7
Number of treatments/medications taken	0.1	0.3	0.4	0.6	0.3
Systolic blood pressure, automated reading	0.1	0.3	0.5	0.7	-0.2
Medication for hormone replacement therapy	0.1	0.1	0.1	0.2	-0.3
Medication: Metformin	0.1	0.2	0.4	-0.6	-0.0
Happiness	0.1	0.1	0.2	-0.3	-0.4
Mouth/teeth dental problems: Dentures	0.1	0.2	0.3	0.3	0.6
Prospective memory result	0.1	0.1	0.1	0.3	-0.3
Birth weight of first child	0.1	0.2	0.4	0.1	-0.6
Birth weight	0.1	0.3	0.4	-0.4	-0.6
Heart disease (mother)	0.1	0.1	0.1	0.3	0.3
Whole body fat mass	0.1	0.3	0.6	-0.8	0.1
Leg fat mass (right)	0.1	0.4	0.8	-0.9	-0.1
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.1	-0.4
Commuting to job workplace: Public transport	0.1	0.1	0.2	-0.1	0.4
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.2	0.1	-0.4
Leg fat mass (left)	0.1	0.4	0.8	-0.9	-0.1
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.0	0.0	0.0	0.2	-0.2
Relative age of first facial hair	0.0	0.0	0.0	0.1	-0.1
Trunk fat percentage	0.0	0.1	0.3	0.5	-0.1
Trunk fat mass	0.0	0.0	0.0	-0.0	-0.0
Mouth/teeth dental problems	0.0	0.0	0.0	0.2	0.0
Illnesses of mother	0.0	0.0	0.1	-0.2	-0.3
Gout (self-reported)	0.0	0.0	0.1	-0.2	-0.1
Body fat percentage	0.0	0.0	0.0	0.0	-0.2
Leg fat percentage (right)	0.0	0.1	0.1	-0.2	-0.4
Shortness of breath walking on level ground	0.0	0.0	0.0	-0.1	-0.1
Illnesses of father: High blood pressure	0.0	0.1	0.1	-0.3	-0.1
Leg fat percentage (left)	0.0	0.2	0.3	-0.3	-0.5
Alcohol drinker status: Previous	0.0	0.0	0.0	-0.1	-0.1

Hub : Genes

SUGP2

Models

Trait associations